High incidence of H‐ras oncogene mutations in squamous cell carcinoma of lip vermilion
Само за регистроване кориснике
1994
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Nine specimens of well‐differentiated squamous cell carcinoma of the lip vermilion have been analyzed for the pressence of H‐ras oncogene mutations, using the technique of hybridization with synthetic oligonucleotide probes on in vitro amplified tumour DNA. Five specimens harbored mutations: four in codon 12 and one in codon 13. This high incidence (55%) of mutated H‐ras genes suggests that their activation may play an important role in lip tumour development and may be connected to the exposure to chemical and/or physical carcinogens.
Кључне речи:
H‐ras / lip cancer / oncogene mutationsИзвор:
Journal of Oral Pathology & Medicine, 1994, 23, 7, 298-301
DOI: 10.1111/j.1600-0714.1994.tb00065.x
ISSN: 0904-2512
PubMed: 7965884
Scopus: 2-s2.0-0028485095
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Milašin, Jelena AU - Pujić, N. AU - Dedović, Nasta AU - Nikolić, Ž. AU - Petrović, V. AU - Dimitrijević, B. PY - 1994 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1061 AB - Nine specimens of well‐differentiated squamous cell carcinoma of the lip vermilion have been analyzed for the pressence of H‐ras oncogene mutations, using the technique of hybridization with synthetic oligonucleotide probes on in vitro amplified tumour DNA. Five specimens harbored mutations: four in codon 12 and one in codon 13. This high incidence (55%) of mutated H‐ras genes suggests that their activation may play an important role in lip tumour development and may be connected to the exposure to chemical and/or physical carcinogens. T2 - Journal of Oral Pathology & Medicine T1 - High incidence of H‐ras oncogene mutations in squamous cell carcinoma of lip vermilion VL - 23 IS - 7 SP - 298 EP - 301 DO - 10.1111/j.1600-0714.1994.tb00065.x ER -
@article{ author = "Milašin, Jelena and Pujić, N. and Dedović, Nasta and Nikolić, Ž. and Petrović, V. and Dimitrijević, B.", year = "1994", abstract = "Nine specimens of well‐differentiated squamous cell carcinoma of the lip vermilion have been analyzed for the pressence of H‐ras oncogene mutations, using the technique of hybridization with synthetic oligonucleotide probes on in vitro amplified tumour DNA. Five specimens harbored mutations: four in codon 12 and one in codon 13. This high incidence (55%) of mutated H‐ras genes suggests that their activation may play an important role in lip tumour development and may be connected to the exposure to chemical and/or physical carcinogens.", journal = "Journal of Oral Pathology & Medicine", title = "High incidence of H‐ras oncogene mutations in squamous cell carcinoma of lip vermilion", volume = "23", number = "7", pages = "298-301", doi = "10.1111/j.1600-0714.1994.tb00065.x" }
Milašin, J., Pujić, N., Dedović, N., Nikolić, Ž., Petrović, V.,& Dimitrijević, B.. (1994). High incidence of H‐ras oncogene mutations in squamous cell carcinoma of lip vermilion. in Journal of Oral Pathology & Medicine, 23(7), 298-301. https://doi.org/10.1111/j.1600-0714.1994.tb00065.x
Milašin J, Pujić N, Dedović N, Nikolić Ž, Petrović V, Dimitrijević B. High incidence of H‐ras oncogene mutations in squamous cell carcinoma of lip vermilion. in Journal of Oral Pathology & Medicine. 1994;23(7):298-301. doi:10.1111/j.1600-0714.1994.tb00065.x .
Milašin, Jelena, Pujić, N., Dedović, Nasta, Nikolić, Ž., Petrović, V., Dimitrijević, B., "High incidence of H‐ras oncogene mutations in squamous cell carcinoma of lip vermilion" in Journal of Oral Pathology & Medicine, 23, no. 7 (1994):298-301, https://doi.org/10.1111/j.1600-0714.1994.tb00065.x . .