Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans
Само за регистроване кориснике
2003
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Objective: A combination of platelet-rich plasma (PRP), bovine porous bone mineral (BPBM) and guided tissue regeneration (GTR) has been shown to be effective as regenerative treatment for intrabony periodontal defects. The purpose of this study was to evaluate the effectiveness of PRP, BPBM and GTR used in combination as regenerative treatment for grade II molar furcation defects in humans. Material and methods: Using a split-mouth design, a total of 52 grade II mandibular molar furcation defects were treated either with PRP/BPBM/GTR (experimental group, n =26) or with an open flap debridement (control group, n =26). The primary outcomes evaluated in this study included changes in pocket depth, attachment level and re-entry bone levels (horizontal and vertical) between baseline and 6 months postoperatively. Results: The results showed that the experimental group presented with significantly greater pocket reduction (4.07+/-0.33 mm for experimental and 2.49+/-0.38 mm for control sites),... gain in clinical attachment (3.29 +/- 0.42 mm for experimental and 1.68+/-0.31 mm for control sites), vertical defect fill (2.56+/- 0.36 mm for experimental and -0.19+/-0.02 for control sites) and horizontal defect fill (2.28+/-0.33 mm for experimental and 0.08+/-0.02 mm for control sites) than the control group. Conclusions: It was concluded that the PRP/BPBM/GTR combined technique is an effective modality of regenerative treatment for mandibular grade II furcation defects. Further studies are necessary to elucidate the role played by each component of the combined therapy in achieving these results.
Кључне речи:
periodontal / regeneration / furcations / platelet-rich plasma / guided tissue regeneration / graftИзвор:
Journal of Clinical Periodontology, 2003, 30, 8, 746-751Издавач:
- Wiley, Hoboken
DOI: 10.1034/j.1600-051X.2003.00368.x
ISSN: 0303-6979
PubMed: 12887344
WoS: 000184336300010
Scopus: 2-s2.0-0142093236
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Leković, Vojislav AU - Camargo, PM AU - Weinlaender, Michael AU - Vasilić, N AU - Aleksić, Zoran AU - Kenney, Barrie PY - 2003 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1187 AB - Objective: A combination of platelet-rich plasma (PRP), bovine porous bone mineral (BPBM) and guided tissue regeneration (GTR) has been shown to be effective as regenerative treatment for intrabony periodontal defects. The purpose of this study was to evaluate the effectiveness of PRP, BPBM and GTR used in combination as regenerative treatment for grade II molar furcation defects in humans. Material and methods: Using a split-mouth design, a total of 52 grade II mandibular molar furcation defects were treated either with PRP/BPBM/GTR (experimental group, n =26) or with an open flap debridement (control group, n =26). The primary outcomes evaluated in this study included changes in pocket depth, attachment level and re-entry bone levels (horizontal and vertical) between baseline and 6 months postoperatively. Results: The results showed that the experimental group presented with significantly greater pocket reduction (4.07+/-0.33 mm for experimental and 2.49+/-0.38 mm for control sites), gain in clinical attachment (3.29 +/- 0.42 mm for experimental and 1.68+/-0.31 mm for control sites), vertical defect fill (2.56+/- 0.36 mm for experimental and -0.19+/-0.02 for control sites) and horizontal defect fill (2.28+/-0.33 mm for experimental and 0.08+/-0.02 mm for control sites) than the control group. Conclusions: It was concluded that the PRP/BPBM/GTR combined technique is an effective modality of regenerative treatment for mandibular grade II furcation defects. Further studies are necessary to elucidate the role played by each component of the combined therapy in achieving these results. PB - Wiley, Hoboken T2 - Journal of Clinical Periodontology T1 - Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans VL - 30 IS - 8 SP - 746 EP - 751 DO - 10.1034/j.1600-051X.2003.00368.x ER -
@article{ author = "Leković, Vojislav and Camargo, PM and Weinlaender, Michael and Vasilić, N and Aleksić, Zoran and Kenney, Barrie", year = "2003", abstract = "Objective: A combination of platelet-rich plasma (PRP), bovine porous bone mineral (BPBM) and guided tissue regeneration (GTR) has been shown to be effective as regenerative treatment for intrabony periodontal defects. The purpose of this study was to evaluate the effectiveness of PRP, BPBM and GTR used in combination as regenerative treatment for grade II molar furcation defects in humans. Material and methods: Using a split-mouth design, a total of 52 grade II mandibular molar furcation defects were treated either with PRP/BPBM/GTR (experimental group, n =26) or with an open flap debridement (control group, n =26). The primary outcomes evaluated in this study included changes in pocket depth, attachment level and re-entry bone levels (horizontal and vertical) between baseline and 6 months postoperatively. Results: The results showed that the experimental group presented with significantly greater pocket reduction (4.07+/-0.33 mm for experimental and 2.49+/-0.38 mm for control sites), gain in clinical attachment (3.29 +/- 0.42 mm for experimental and 1.68+/-0.31 mm for control sites), vertical defect fill (2.56+/- 0.36 mm for experimental and -0.19+/-0.02 for control sites) and horizontal defect fill (2.28+/-0.33 mm for experimental and 0.08+/-0.02 mm for control sites) than the control group. Conclusions: It was concluded that the PRP/BPBM/GTR combined technique is an effective modality of regenerative treatment for mandibular grade II furcation defects. Further studies are necessary to elucidate the role played by each component of the combined therapy in achieving these results.", publisher = "Wiley, Hoboken", journal = "Journal of Clinical Periodontology", title = "Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans", volume = "30", number = "8", pages = "746-751", doi = "10.1034/j.1600-051X.2003.00368.x" }
Leković, V., Camargo, P., Weinlaender, M., Vasilić, N., Aleksić, Z.,& Kenney, B.. (2003). Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans. in Journal of Clinical Periodontology Wiley, Hoboken., 30(8), 746-751. https://doi.org/10.1034/j.1600-051X.2003.00368.x
Leković V, Camargo P, Weinlaender M, Vasilić N, Aleksić Z, Kenney B. Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans. in Journal of Clinical Periodontology. 2003;30(8):746-751. doi:10.1034/j.1600-051X.2003.00368.x .
Leković, Vojislav, Camargo, PM, Weinlaender, Michael, Vasilić, N, Aleksić, Zoran, Kenney, Barrie, "Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans" in Journal of Clinical Periodontology, 30, no. 8 (2003):746-751, https://doi.org/10.1034/j.1600-051X.2003.00368.x . .