The therapeutic use of botulinum toxin in cervical and maxillofacial conditions: an evidence-based review
Само за регистроване кориснике
2007
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Introduction. The role of botulinum toxin as a therapeutic agent for several conditions is expanding. We sought to determine if botulinum toxin is safe and effective in treating patients with cervical dystonia and maxillofacial conditions. Our purpose was to establish a safety and efficacy profile to determine whether or not this treatment may be used prophylactically in patients undergoing dental implant therapy. Methods. We performed a systematic search of the literature to identify randomized clinical trials evaluating patients treated with botulinum toxin as an adjunct to dental implant therapy, maxillofacial conditions including temporomandibular disorders (TMD), and cervical dystonia. Results. Four randomized controlled trials (RCTs) met our search criteria in the area of cervical dystonia and chronic facial pain. No RCTs were identified evaluating dental implant therapy. Patients with cervical dystonia exhibited significant improvements in baseline functional, pain, and global a...ssessments compared to placebo. Adverse events were mild and transient with numbers needed to harm (NNH) ranging from 12 to 17. Patients with chronic facial pain improved significantly from baseline in terms of pain compared to placebo. Rates of adverse events were less than 1%. Conclusion. Botulinum toxin appears relatively safe and effective in treating cervical dystonia and chronic facial pain associated with masticatory hyperactivity. No literature exists evaluating its use in dental implantology. Randomized clinical trials are warranted to determine its safety and efficacy in dental implantology and other maxillofacial conditions such as bruxism.
Извор:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology, 2007, 104, 2, E1-E11Издавач:
- Mosby-Elsevier, New York
DOI: 10.1016/j.tripleo.2007.02.004
ISSN: 1079-2104
PubMed: 17560141
WoS: 000248604900021
Scopus: 2-s2.0-34447302328
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Ihde, Stefan AU - Konstantinović, Vitomir PY - 2007 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1327 AB - Introduction. The role of botulinum toxin as a therapeutic agent for several conditions is expanding. We sought to determine if botulinum toxin is safe and effective in treating patients with cervical dystonia and maxillofacial conditions. Our purpose was to establish a safety and efficacy profile to determine whether or not this treatment may be used prophylactically in patients undergoing dental implant therapy. Methods. We performed a systematic search of the literature to identify randomized clinical trials evaluating patients treated with botulinum toxin as an adjunct to dental implant therapy, maxillofacial conditions including temporomandibular disorders (TMD), and cervical dystonia. Results. Four randomized controlled trials (RCTs) met our search criteria in the area of cervical dystonia and chronic facial pain. No RCTs were identified evaluating dental implant therapy. Patients with cervical dystonia exhibited significant improvements in baseline functional, pain, and global assessments compared to placebo. Adverse events were mild and transient with numbers needed to harm (NNH) ranging from 12 to 17. Patients with chronic facial pain improved significantly from baseline in terms of pain compared to placebo. Rates of adverse events were less than 1%. Conclusion. Botulinum toxin appears relatively safe and effective in treating cervical dystonia and chronic facial pain associated with masticatory hyperactivity. No literature exists evaluating its use in dental implantology. Randomized clinical trials are warranted to determine its safety and efficacy in dental implantology and other maxillofacial conditions such as bruxism. PB - Mosby-Elsevier, New York T2 - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology T1 - The therapeutic use of botulinum toxin in cervical and maxillofacial conditions: an evidence-based review VL - 104 IS - 2 SP - E1 EP - E11 DO - 10.1016/j.tripleo.2007.02.004 ER -
@article{ author = "Ihde, Stefan and Konstantinović, Vitomir", year = "2007", abstract = "Introduction. The role of botulinum toxin as a therapeutic agent for several conditions is expanding. We sought to determine if botulinum toxin is safe and effective in treating patients with cervical dystonia and maxillofacial conditions. Our purpose was to establish a safety and efficacy profile to determine whether or not this treatment may be used prophylactically in patients undergoing dental implant therapy. Methods. We performed a systematic search of the literature to identify randomized clinical trials evaluating patients treated with botulinum toxin as an adjunct to dental implant therapy, maxillofacial conditions including temporomandibular disorders (TMD), and cervical dystonia. Results. Four randomized controlled trials (RCTs) met our search criteria in the area of cervical dystonia and chronic facial pain. No RCTs were identified evaluating dental implant therapy. Patients with cervical dystonia exhibited significant improvements in baseline functional, pain, and global assessments compared to placebo. Adverse events were mild and transient with numbers needed to harm (NNH) ranging from 12 to 17. Patients with chronic facial pain improved significantly from baseline in terms of pain compared to placebo. Rates of adverse events were less than 1%. Conclusion. Botulinum toxin appears relatively safe and effective in treating cervical dystonia and chronic facial pain associated with masticatory hyperactivity. No literature exists evaluating its use in dental implantology. Randomized clinical trials are warranted to determine its safety and efficacy in dental implantology and other maxillofacial conditions such as bruxism.", publisher = "Mosby-Elsevier, New York", journal = "Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology", title = "The therapeutic use of botulinum toxin in cervical and maxillofacial conditions: an evidence-based review", volume = "104", number = "2", pages = "E1-E11", doi = "10.1016/j.tripleo.2007.02.004" }
Ihde, S.,& Konstantinović, V.. (2007). The therapeutic use of botulinum toxin in cervical and maxillofacial conditions: an evidence-based review. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology Mosby-Elsevier, New York., 104(2), E1-E11. https://doi.org/10.1016/j.tripleo.2007.02.004
Ihde S, Konstantinović V. The therapeutic use of botulinum toxin in cervical and maxillofacial conditions: an evidence-based review. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology. 2007;104(2):E1-E11. doi:10.1016/j.tripleo.2007.02.004 .
Ihde, Stefan, Konstantinović, Vitomir, "The therapeutic use of botulinum toxin in cervical and maxillofacial conditions: an evidence-based review" in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology, 104, no. 2 (2007):E1-E11, https://doi.org/10.1016/j.tripleo.2007.02.004 . .