Приказ основних података о документу
Mast cells in periapical lesions: potential role in their pathogenesis
dc.creator | Dražić, Radojica | |
dc.creator | Sopta, Jelena | |
dc.creator | Minić, Arsa J. | |
dc.date.accessioned | 2020-07-02T12:26:11Z | |
dc.date.available | 2020-07-02T12:26:11Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 0904-2512 | |
dc.identifier.uri | https://smile.stomf.bg.ac.rs/handle/123456789/1521 | |
dc.description.abstract | Objective: The aim of this study was to qualitatively and semi-quantitatively analyze mast cells in periapical lesions. Materials and methods: Biopsy specimens of 96 periapical lesions were stained with hematoxylin-eosin, histochemical Giemsa and immunohistochemical CD 117 (C kit) antibody. Mast cell count below 100 mast cells on 1000 fields of high power magnification was noted as 'negative', 101-400 as 'mild', 401-800 cells as 'moderate', and over 800 cells as 'severe'. Results: Mast cells are found in 68 (70.8%) lesions. The presence of mast cells was greater in cysts than in granulomas (P lt 0.0028). There was no difference in semi-quantitative expression of CD 117 in granulomas and cysts (P > 0.05). Mast cells were placed in both: inflammatory infiltrate and in fibroblastic areas of periapical lesions, and their presence was most frequently mild to moderate. Conclusions: The findings of present study could suggest a role of mast cells in regulation of cellular immune mechanisms in periapical lesions, balancing between alterative and reparatory processes in inflamed periapical tissue. | en |
dc.publisher | Wiley-Blackwell Publishing, Inc, Malden | |
dc.rights | restrictedAccess | |
dc.source | Journal of Oral Pathology & Medicine | |
dc.subject | CD 117 | en |
dc.subject | mast cells | en |
dc.subject | periapical lesions | en |
dc.title | Mast cells in periapical lesions: potential role in their pathogenesis | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Сопта, Јелена; Минић, Aрса Ј.; Дражић, Радојица; | |
dc.citation.volume | 39 | |
dc.citation.issue | 3 | |
dc.citation.spage | 257 | |
dc.citation.epage | 262 | |
dc.citation.other | 39(3): 257-262 | |
dc.citation.rank | M21 | |
dc.identifier.wos | 000274668700010 | |
dc.identifier.doi | 10.1111/j.1600-0714.2009.00870.x | |
dc.identifier.pmid | 20359310 | |
dc.identifier.scopus | 2-s2.0-77249172276 | |
dc.type.version | publishedVersion |