Приказ основних података о документу
Salivary interleukin-8 levels in children suffering from Type 1 diabetes mellitus
dc.creator | Daković, Dragana | |
dc.creator | Čolić, Miodrag | |
dc.creator | Čakić, Saša | |
dc.creator | Mileusnić, Ivan | |
dc.creator | Hajduković, Zoran | |
dc.creator | Stamatović, Novak | |
dc.date.accessioned | 2020-07-02T12:47:59Z | |
dc.date.available | 2020-07-02T12:47:59Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 1053-4628 | |
dc.identifier.uri | https://smile.stomf.bg.ac.rs/handle/123456789/1852 | |
dc.description.abstract | Objective: The aim of this study was to investigate the differences between the salivary levels of IL-8 in patients with Type I diabetes mellitus (DM) with (DM+P) or without (DM-P) concomitant periodontitis and healthy subjects. The correlations between the levels of these cytokines and clinical periodontal parameters were also established Methods: Twenty children and adolescents with Type I DM (10 diagnosed with periodontitis, 10 presenting no signs of periodontitis) and a control group consisting of 20 healthy children and adolescents aged 7-18 years were recruited for this study. Results: The Salivary IL-8 level was statistically significantly (p lt 0.005) elevated in subjects with Type 1 DM (474.47 +/- 716.76) compared to non-diabetic control group (101.99 +/- 68.32). There was no difference (p>0.05) in the salivary IL-8 level when subjects with Type I DM with concomitant periodontitis were compared to diabetics without periodontitis. When the salivary IL-8 level in subjects with Type I DM was correlated with the clinical parameters, no statistical significance was found Conclusion: An elevated salivary IL-8 level in subjects with Type 1 DM without concomitant periodontitis plays a major role in the development of diabetic micro and macroangiopathy and pathogenesis of atherosclerosis. Consequently, this may offer a basis for the assessment of risk, prophylaxis and treatment of diabetic complications. | en |
dc.publisher | Journal Pedodontics Inc, Birmingham | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175075/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41008/RS// | |
dc.rights | restrictedAccess | |
dc.source | Journal of Clinical Pediatric Dentistry | |
dc.subject | Type 1 diabetes mellitus | en |
dc.subject | periodontitis | en |
dc.subject | children | en |
dc.subject | cytokines | en |
dc.subject | interleukin-8 | en |
dc.title | Salivary interleukin-8 levels in children suffering from Type 1 diabetes mellitus | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Чакић, Саша; Чолић, Миодраг; Стаматовић, Новак; Хајдуковић, Зоран; Даковић, Драгана; Милеуснић, Иван; | |
dc.citation.volume | 37 | |
dc.citation.issue | 4 | |
dc.citation.spage | 377 | |
dc.citation.epage | 380 | |
dc.citation.other | 37(4): 377-380 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000335092800008 | |
dc.identifier.doi | 10.17796/jcpd.37.4.l135531h4542gj66 | |
dc.identifier.pmid | 24046985 | |
dc.identifier.scopus | 2-s2.0-84885932613 | |
dc.type.version | publishedVersion |