Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines
Нема приказа
Аутори
Janović, AleksaMilovanović, Petar
Hahn, Michael
Rakočević, Zoran
Amling, Michael
Busse, Bjoern
Dimitrijević, Milovan
Đurić, Marija
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Background/AimLe Fort lines have traditionally been considered as zones of weakness in the mid-facial skeleton although the structural basis of increased bone fragility at these sites has not yet been investigated. Considering recent findings of occlusal loading-related regional heterogeneity in the mid-facial bone micro-architecture, the aim of this study was to explore whether such heterogeneity in cortical and cancellous bone micro-architecture may contribute to increased fragility at Le Fort fracture sites. Materials and MethodsTwenty-five cortical and thirteen cancellous bone specimens were harvested from a dry skull and analyzed by micro-CT. Specimens were classified into Le Fort or Non-Le Fort groups based on their location in the mid-facial skeleton. ResultsCortical bone along Le Fort lines showed tendencies toward lower thickness (1.50.63 vs 1.75 +/- 0.79; P=.39) and greater porosity (11.48 +/- 5.67 vs 10.28 +/- 5.28; P=.59). A significant difference was detected in the trabec...ular degree of anisotropy which was higher in cancellous bone from Le Fort fracture sites (2.14 +/- 0.69 vs 1.58 +/- 0.34; P=.02). ConclusionsRegional heterogeneity in cortical bone micro-architecture could not fully explain increased fragility of the mid-facial skeleton at the Le Fort lines. However, regional differences in trabecular bone anisotropy may contribute to increased bone fragility.
Кључне речи:
bone / fracture / Le Fort / micro-architecture / mid-facial skeletonИзвор:
Dental Traumatology, 2017, 33, 4, 300-306Издавач:
- Wiley, Hoboken
Финансирање / пројекти:
- Функционални, функционализовани и усавршени нано материјали (RS-45005)
- South-East-Europe Cooperation of University Medical Center Hamburg-Eppendorf
DOI: 10.1111/edt.12333
ISSN: 1600-4469
PubMed: 28258969
WoS: 000405118400010
Scopus: 2-s2.0-85018844318
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Janović, Aleksa AU - Milovanović, Petar AU - Hahn, Michael AU - Rakočević, Zoran AU - Amling, Michael AU - Busse, Bjoern AU - Dimitrijević, Milovan AU - Đurić, Marija PY - 2017 UR - https://smile.stomf.bg.ac.rs/handle/123456789/2183 AB - Background/AimLe Fort lines have traditionally been considered as zones of weakness in the mid-facial skeleton although the structural basis of increased bone fragility at these sites has not yet been investigated. Considering recent findings of occlusal loading-related regional heterogeneity in the mid-facial bone micro-architecture, the aim of this study was to explore whether such heterogeneity in cortical and cancellous bone micro-architecture may contribute to increased fragility at Le Fort fracture sites. Materials and MethodsTwenty-five cortical and thirteen cancellous bone specimens were harvested from a dry skull and analyzed by micro-CT. Specimens were classified into Le Fort or Non-Le Fort groups based on their location in the mid-facial skeleton. ResultsCortical bone along Le Fort lines showed tendencies toward lower thickness (1.50.63 vs 1.75 +/- 0.79; P=.39) and greater porosity (11.48 +/- 5.67 vs 10.28 +/- 5.28; P=.59). A significant difference was detected in the trabecular degree of anisotropy which was higher in cancellous bone from Le Fort fracture sites (2.14 +/- 0.69 vs 1.58 +/- 0.34; P=.02). ConclusionsRegional heterogeneity in cortical bone micro-architecture could not fully explain increased fragility of the mid-facial skeleton at the Le Fort lines. However, regional differences in trabecular bone anisotropy may contribute to increased bone fragility. PB - Wiley, Hoboken T2 - Dental Traumatology T1 - Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines VL - 33 IS - 4 SP - 300 EP - 306 DO - 10.1111/edt.12333 ER -
@article{ author = "Janović, Aleksa and Milovanović, Petar and Hahn, Michael and Rakočević, Zoran and Amling, Michael and Busse, Bjoern and Dimitrijević, Milovan and Đurić, Marija", year = "2017", abstract = "Background/AimLe Fort lines have traditionally been considered as zones of weakness in the mid-facial skeleton although the structural basis of increased bone fragility at these sites has not yet been investigated. Considering recent findings of occlusal loading-related regional heterogeneity in the mid-facial bone micro-architecture, the aim of this study was to explore whether such heterogeneity in cortical and cancellous bone micro-architecture may contribute to increased fragility at Le Fort fracture sites. Materials and MethodsTwenty-five cortical and thirteen cancellous bone specimens were harvested from a dry skull and analyzed by micro-CT. Specimens were classified into Le Fort or Non-Le Fort groups based on their location in the mid-facial skeleton. ResultsCortical bone along Le Fort lines showed tendencies toward lower thickness (1.50.63 vs 1.75 +/- 0.79; P=.39) and greater porosity (11.48 +/- 5.67 vs 10.28 +/- 5.28; P=.59). A significant difference was detected in the trabecular degree of anisotropy which was higher in cancellous bone from Le Fort fracture sites (2.14 +/- 0.69 vs 1.58 +/- 0.34; P=.02). ConclusionsRegional heterogeneity in cortical bone micro-architecture could not fully explain increased fragility of the mid-facial skeleton at the Le Fort lines. However, regional differences in trabecular bone anisotropy may contribute to increased bone fragility.", publisher = "Wiley, Hoboken", journal = "Dental Traumatology", title = "Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines", volume = "33", number = "4", pages = "300-306", doi = "10.1111/edt.12333" }
Janović, A., Milovanović, P., Hahn, M., Rakočević, Z., Amling, M., Busse, B., Dimitrijević, M.,& Đurić, M.. (2017). Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines. in Dental Traumatology Wiley, Hoboken., 33(4), 300-306. https://doi.org/10.1111/edt.12333
Janović A, Milovanović P, Hahn M, Rakočević Z, Amling M, Busse B, Dimitrijević M, Đurić M. Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines. in Dental Traumatology. 2017;33(4):300-306. doi:10.1111/edt.12333 .
Janović, Aleksa, Milovanović, Petar, Hahn, Michael, Rakočević, Zoran, Amling, Michael, Busse, Bjoern, Dimitrijević, Milovan, Đurić, Marija, "Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines" in Dental Traumatology, 33, no. 4 (2017):300-306, https://doi.org/10.1111/edt.12333 . .