Maxillary infiltration anaesthesia by ropivacaine for upper third molar surgery
Samo za registrovane korisnike
2010
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The main purpose of this Study was to assess the clinical efficacy and haemodynamic effects of ropivacaine for infiltration anaesthesia in patients undergoing surgical removal of upper third molars. The safety profile of ropivacaine was also Studied by investigating the maximal venous plasma concentration of ropivacaine and the reactivity to ropivacaine of isolated human infraorbital arteries. Ropivacaine in concentrations of 0.5, 0.75 and 1% achieved dose-dependent parameters of maxillary infiltration aneasthesia, clinically relevant in concentrations 0.75 and 1%. Postoperative needs for analgesics were observed in 67-100% of patients. Haemodynamic parameters were stable during surgery with significant changes occuring 10 min after surgery. After maxillary infiltration of 2.0 ml 1% ropivacaine, the maximum venous plasma concentration Cmax) was 82 +/- 15 mg/l. On isolated human infraorbital artery, ropivacaine (10(-4) M) induced endothelium-independent contraction. This study suggests ...that 0.75 and 1% ropivacaine offers adequate and safe intraoperative analgesia but not Successful postoperative pain control for the surgical removal Of upper third molars.
Ključne reči:
ropivacaine / maxillary infiltration anaesthesia / cardiovascular parameters / ropivacaine-induced vasoconstriction / C-max and t(max)Izvor:
International Journal of Oral & Maxillofacial Surgery, 2010, 39, 1, 36-41Izdavač:
- Churchill Livingstone, Edinburgh
DOI: 10.1016/j.ijom.2009.11.009
ISSN: 0901-5027
PubMed: 20005673
WoS: 000274842400007
Scopus: 2-s2.0-74249083189
Kolekcije
Institucija/grupa
Stomatološki fakultetTY - JOUR AU - Brković, Božidar AU - Zlatković, M. AU - Jovanović, D. AU - Stojić, Dragica PY - 2010 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1530 AB - The main purpose of this Study was to assess the clinical efficacy and haemodynamic effects of ropivacaine for infiltration anaesthesia in patients undergoing surgical removal of upper third molars. The safety profile of ropivacaine was also Studied by investigating the maximal venous plasma concentration of ropivacaine and the reactivity to ropivacaine of isolated human infraorbital arteries. Ropivacaine in concentrations of 0.5, 0.75 and 1% achieved dose-dependent parameters of maxillary infiltration aneasthesia, clinically relevant in concentrations 0.75 and 1%. Postoperative needs for analgesics were observed in 67-100% of patients. Haemodynamic parameters were stable during surgery with significant changes occuring 10 min after surgery. After maxillary infiltration of 2.0 ml 1% ropivacaine, the maximum venous plasma concentration Cmax) was 82 +/- 15 mg/l. On isolated human infraorbital artery, ropivacaine (10(-4) M) induced endothelium-independent contraction. This study suggests that 0.75 and 1% ropivacaine offers adequate and safe intraoperative analgesia but not Successful postoperative pain control for the surgical removal Of upper third molars. PB - Churchill Livingstone, Edinburgh T2 - International Journal of Oral & Maxillofacial Surgery T1 - Maxillary infiltration anaesthesia by ropivacaine for upper third molar surgery VL - 39 IS - 1 SP - 36 EP - 41 DO - 10.1016/j.ijom.2009.11.009 ER -
@article{ author = "Brković, Božidar and Zlatković, M. and Jovanović, D. and Stojić, Dragica", year = "2010", abstract = "The main purpose of this Study was to assess the clinical efficacy and haemodynamic effects of ropivacaine for infiltration anaesthesia in patients undergoing surgical removal of upper third molars. The safety profile of ropivacaine was also Studied by investigating the maximal venous plasma concentration of ropivacaine and the reactivity to ropivacaine of isolated human infraorbital arteries. Ropivacaine in concentrations of 0.5, 0.75 and 1% achieved dose-dependent parameters of maxillary infiltration aneasthesia, clinically relevant in concentrations 0.75 and 1%. Postoperative needs for analgesics were observed in 67-100% of patients. Haemodynamic parameters were stable during surgery with significant changes occuring 10 min after surgery. After maxillary infiltration of 2.0 ml 1% ropivacaine, the maximum venous plasma concentration Cmax) was 82 +/- 15 mg/l. On isolated human infraorbital artery, ropivacaine (10(-4) M) induced endothelium-independent contraction. This study suggests that 0.75 and 1% ropivacaine offers adequate and safe intraoperative analgesia but not Successful postoperative pain control for the surgical removal Of upper third molars.", publisher = "Churchill Livingstone, Edinburgh", journal = "International Journal of Oral & Maxillofacial Surgery", title = "Maxillary infiltration anaesthesia by ropivacaine for upper third molar surgery", volume = "39", number = "1", pages = "36-41", doi = "10.1016/j.ijom.2009.11.009" }
Brković, B., Zlatković, M., Jovanović, D.,& Stojić, D.. (2010). Maxillary infiltration anaesthesia by ropivacaine for upper third molar surgery. in International Journal of Oral & Maxillofacial Surgery Churchill Livingstone, Edinburgh., 39(1), 36-41. https://doi.org/10.1016/j.ijom.2009.11.009
Brković B, Zlatković M, Jovanović D, Stojić D. Maxillary infiltration anaesthesia by ropivacaine for upper third molar surgery. in International Journal of Oral & Maxillofacial Surgery. 2010;39(1):36-41. doi:10.1016/j.ijom.2009.11.009 .
Brković, Božidar, Zlatković, M., Jovanović, D., Stojić, Dragica, "Maxillary infiltration anaesthesia by ropivacaine for upper third molar surgery" in International Journal of Oral & Maxillofacial Surgery, 39, no. 1 (2010):36-41, https://doi.org/10.1016/j.ijom.2009.11.009 . .