The Effect of Topical Doxycycline on Corneal Neovascularization
Abstract
Purpose: To examine the effect of topical doxycycline on human corneal neovascularization (CONV). Materials and methods: Six eyes of six patients with CONV received topical 1% doxycycline four times per day for three weeks and monitored for a total of one year. Ophthalmic evaluations included visual acuity, tonometry, slit-lamp examination, conjunctival swabs, quantification of CONV and photography. Results: CONV either disappeared or was attenuated, shortened and less dense in five of six patients. There were no adverse effects. Conclusion: Topical doxycycline was effective in reducing CONV and healing of the ocular surface.
Keywords:
Cornea / doxycycline / neovascularizationSource:
Current Eye Research, 2014, 39, 2, 142-148Publisher:
- Taylor & Francis Inc, Philadelphia
DOI: 10.3109/02713683.2013.833246
ISSN: 0271-3683
PubMed: 23964705
WoS: 000330070500004
Scopus: 2-s2.0-84893004728
Collections
Institution/Community
Stomatološki fakultetTY - JOUR AU - Jovanović, Vesna AU - Nikolić, Ljubisa PY - 2014 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1943 AB - Purpose: To examine the effect of topical doxycycline on human corneal neovascularization (CONV). Materials and methods: Six eyes of six patients with CONV received topical 1% doxycycline four times per day for three weeks and monitored for a total of one year. Ophthalmic evaluations included visual acuity, tonometry, slit-lamp examination, conjunctival swabs, quantification of CONV and photography. Results: CONV either disappeared or was attenuated, shortened and less dense in five of six patients. There were no adverse effects. Conclusion: Topical doxycycline was effective in reducing CONV and healing of the ocular surface. PB - Taylor & Francis Inc, Philadelphia T2 - Current Eye Research T1 - The Effect of Topical Doxycycline on Corneal Neovascularization VL - 39 IS - 2 SP - 142 EP - 148 DO - 10.3109/02713683.2013.833246 ER -
@article{ author = "Jovanović, Vesna and Nikolić, Ljubisa", year = "2014", abstract = "Purpose: To examine the effect of topical doxycycline on human corneal neovascularization (CONV). Materials and methods: Six eyes of six patients with CONV received topical 1% doxycycline four times per day for three weeks and monitored for a total of one year. Ophthalmic evaluations included visual acuity, tonometry, slit-lamp examination, conjunctival swabs, quantification of CONV and photography. Results: CONV either disappeared or was attenuated, shortened and less dense in five of six patients. There were no adverse effects. Conclusion: Topical doxycycline was effective in reducing CONV and healing of the ocular surface.", publisher = "Taylor & Francis Inc, Philadelphia", journal = "Current Eye Research", title = "The Effect of Topical Doxycycline on Corneal Neovascularization", volume = "39", number = "2", pages = "142-148", doi = "10.3109/02713683.2013.833246" }
Jovanović, V.,& Nikolić, L.. (2014). The Effect of Topical Doxycycline on Corneal Neovascularization. in Current Eye Research Taylor & Francis Inc, Philadelphia., 39(2), 142-148. https://doi.org/10.3109/02713683.2013.833246
Jovanović V, Nikolić L. The Effect of Topical Doxycycline on Corneal Neovascularization. in Current Eye Research. 2014;39(2):142-148. doi:10.3109/02713683.2013.833246 .
Jovanović, Vesna, Nikolić, Ljubisa, "The Effect of Topical Doxycycline on Corneal Neovascularization" in Current Eye Research, 39, no. 2 (2014):142-148, https://doi.org/10.3109/02713683.2013.833246 . .