Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study
Samo za registrovane korisnike
2017
Autori
Brković, BožidarAndrić, Miroslav
Ćalasan, Dejan
Milić, Marija
Stepić, Jelena
Vučetić, Milan
Brajković, Denis
Todorović, Ljubomir
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The purpose of this study was to investigate postoperative analgesic effect of ropivacaine administered as main or supplemental injection for the inferior alveolar nerve block (IANB) in patients undergoing lower third molar surgery. The double-blind randomized study comprised 72 healthy patients. All patients received two blocks, the IANB for surgical procedure + IANB after surgery for postoperative pain control, and were divided into three groups: (1) 2 % lidocaine/epinephrine + 1 % ropivacaine, (2) 2 % lidocaine/epinephrine + saline, and (3) 1 % ropivacaine + saline. The occurrence of postoperative pain, pain intensity and analgesic requirements were recorded. Data were statistically analyzed using chi-square, Fisher, and Kruskal-Wallis tests and analysis of variance (ANOVA) with Bonferroni and Tukey correction. Ropivacaine was more successful than lidocaine/epinephrine in obtaining duration of postoperative analgesia, reduction of pain, and analgesic requirements whether ropivacaine... was used for surgical block or administered as a supplemental injection after surgery. Ropivacaine (1 %, 2 ml) resulted in effective postoperative analgesia after lower third molar surgery. Since pain control related to third molar surgery requires the effective surgical anesthesia and postoperative analgesia, the use of 1 % ropivacaine could be clinically relevant in a selection of appropriate pain control regimen for both surgical procedure and early postsurgical treatment.
Ključne reči:
Ropivacaine / Inferior alveolar nerve block / Impacted lower third molar surgery / Postoperative analgesiaIzvor:
Clinical Oral Investigations, 2017, 21, 3, 779-785Izdavač:
- Springer Heidelberg, Heidelberg
Finansiranje / projekti:
DOI: 10.1007/s00784-016-1831-2
ISSN: 1432-6981
PubMed: 27114091
WoS: 000398710700007
Scopus: 2-s2.0-84964440123
Kolekcije
Institucija/grupa
Stomatološki fakultetTY - JOUR AU - Brković, Božidar AU - Andrić, Miroslav AU - Ćalasan, Dejan AU - Milić, Marija AU - Stepić, Jelena AU - Vučetić, Milan AU - Brajković, Denis AU - Todorović, Ljubomir PY - 2017 UR - https://smile.stomf.bg.ac.rs/handle/123456789/2241 AB - The purpose of this study was to investigate postoperative analgesic effect of ropivacaine administered as main or supplemental injection for the inferior alveolar nerve block (IANB) in patients undergoing lower third molar surgery. The double-blind randomized study comprised 72 healthy patients. All patients received two blocks, the IANB for surgical procedure + IANB after surgery for postoperative pain control, and were divided into three groups: (1) 2 % lidocaine/epinephrine + 1 % ropivacaine, (2) 2 % lidocaine/epinephrine + saline, and (3) 1 % ropivacaine + saline. The occurrence of postoperative pain, pain intensity and analgesic requirements were recorded. Data were statistically analyzed using chi-square, Fisher, and Kruskal-Wallis tests and analysis of variance (ANOVA) with Bonferroni and Tukey correction. Ropivacaine was more successful than lidocaine/epinephrine in obtaining duration of postoperative analgesia, reduction of pain, and analgesic requirements whether ropivacaine was used for surgical block or administered as a supplemental injection after surgery. Ropivacaine (1 %, 2 ml) resulted in effective postoperative analgesia after lower third molar surgery. Since pain control related to third molar surgery requires the effective surgical anesthesia and postoperative analgesia, the use of 1 % ropivacaine could be clinically relevant in a selection of appropriate pain control regimen for both surgical procedure and early postsurgical treatment. PB - Springer Heidelberg, Heidelberg T2 - Clinical Oral Investigations T1 - Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study VL - 21 IS - 3 SP - 779 EP - 785 DO - 10.1007/s00784-016-1831-2 ER -
@article{ author = "Brković, Božidar and Andrić, Miroslav and Ćalasan, Dejan and Milić, Marija and Stepić, Jelena and Vučetić, Milan and Brajković, Denis and Todorović, Ljubomir", year = "2017", abstract = "The purpose of this study was to investigate postoperative analgesic effect of ropivacaine administered as main or supplemental injection for the inferior alveolar nerve block (IANB) in patients undergoing lower third molar surgery. The double-blind randomized study comprised 72 healthy patients. All patients received two blocks, the IANB for surgical procedure + IANB after surgery for postoperative pain control, and were divided into three groups: (1) 2 % lidocaine/epinephrine + 1 % ropivacaine, (2) 2 % lidocaine/epinephrine + saline, and (3) 1 % ropivacaine + saline. The occurrence of postoperative pain, pain intensity and analgesic requirements were recorded. Data were statistically analyzed using chi-square, Fisher, and Kruskal-Wallis tests and analysis of variance (ANOVA) with Bonferroni and Tukey correction. Ropivacaine was more successful than lidocaine/epinephrine in obtaining duration of postoperative analgesia, reduction of pain, and analgesic requirements whether ropivacaine was used for surgical block or administered as a supplemental injection after surgery. Ropivacaine (1 %, 2 ml) resulted in effective postoperative analgesia after lower third molar surgery. Since pain control related to third molar surgery requires the effective surgical anesthesia and postoperative analgesia, the use of 1 % ropivacaine could be clinically relevant in a selection of appropriate pain control regimen for both surgical procedure and early postsurgical treatment.", publisher = "Springer Heidelberg, Heidelberg", journal = "Clinical Oral Investigations", title = "Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study", volume = "21", number = "3", pages = "779-785", doi = "10.1007/s00784-016-1831-2" }
Brković, B., Andrić, M., Ćalasan, D., Milić, M., Stepić, J., Vučetić, M., Brajković, D.,& Todorović, L.. (2017). Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study. in Clinical Oral Investigations Springer Heidelberg, Heidelberg., 21(3), 779-785. https://doi.org/10.1007/s00784-016-1831-2
Brković B, Andrić M, Ćalasan D, Milić M, Stepić J, Vučetić M, Brajković D, Todorović L. Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study. in Clinical Oral Investigations. 2017;21(3):779-785. doi:10.1007/s00784-016-1831-2 .
Brković, Božidar, Andrić, Miroslav, Ćalasan, Dejan, Milić, Marija, Stepić, Jelena, Vučetić, Milan, Brajković, Denis, Todorović, Ljubomir, "Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study" in Clinical Oral Investigations, 21, no. 3 (2017):779-785, https://doi.org/10.1007/s00784-016-1831-2 . .