Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Background
The mortality of oral squamous cell cancer (OSCC) in Serbia increased in the last decade. Recent studies on the Serbian population focused mainly on the epidemiological aspect of OSCC. This study aimed to investigate the demographic and imaging features of OSCC in the Serbian population at the time of diagnosis.
Methods
We retrospectively analyzed computed tomography (CT) images of 276 patients with OSCC diagnosed between 2017 and 2022. Age, gender, tumor site, tumor volume (CT-TV, in cm3), depth of invasion (CT-DOI, in mm), and bone invasion (CT-BI, in %) were evaluated. TNM status and tumor stage were also analyzed. All parameters were analyzed with appropriate statistical tests.
Results
The mean age was 62.32 ± 11.39 and 63.25 ± 11.71 for males and females, respectively. Male to female ratio was 1.63:1. The tongue (36.2%), mouth floor (21.0%), and alveolar ridge (19.9%) were the most frequent sites of OSCC. There was a significant gender-related difference in OSC...C distribution between oral cavity subsites (Z=-4.225; p < 0.001). Mean values of CT-TV in males (13.8 ± 21.5) and females (5.4 ± 6.8) were significantly different (t = 4.620; p < 0.001). CT-DOI also differed significantly (t = 4.621; p < 0.001) between males (14.4 ± 7.4) and females (10.7 ± 4.4). CT-BI was detected in 30.1%, the most common in the alveolar ridge OSCC. T2 tumor status (31.4%) and stage IVA (28.3%) were the most dominant at the time of diagnosis. Metastatic lymph nodes were detected in 41.1%.
Conclusion
Our findings revealed significant gender-related differences in OSCC imaging features. The predominance of moderate and advanced tumor stages indicates a long time interval to the OSCC diagnosis.
Кључне речи:
Squamous cell Cancer / Oral cavity / Demography / X-Ray computed Tomograph / Retrospective studiesИзвор:
BMC Oral Health, 29-01-2024, 24, 141Издавач:
- Springer
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Janović, Aleksa AU - Bracanović, Đurđa AU - Antić, Svetlana AU - Marković-Vasiljković, Biljana PY - 2024-01-29 UR - https://smile.stomf.bg.ac.rs/handle/123456789/3297 AB - Background The mortality of oral squamous cell cancer (OSCC) in Serbia increased in the last decade. Recent studies on the Serbian population focused mainly on the epidemiological aspect of OSCC. This study aimed to investigate the demographic and imaging features of OSCC in the Serbian population at the time of diagnosis. Methods We retrospectively analyzed computed tomography (CT) images of 276 patients with OSCC diagnosed between 2017 and 2022. Age, gender, tumor site, tumor volume (CT-TV, in cm3), depth of invasion (CT-DOI, in mm), and bone invasion (CT-BI, in %) were evaluated. TNM status and tumor stage were also analyzed. All parameters were analyzed with appropriate statistical tests. Results The mean age was 62.32 ± 11.39 and 63.25 ± 11.71 for males and females, respectively. Male to female ratio was 1.63:1. The tongue (36.2%), mouth floor (21.0%), and alveolar ridge (19.9%) were the most frequent sites of OSCC. There was a significant gender-related difference in OSCC distribution between oral cavity subsites (Z=-4.225; p < 0.001). Mean values of CT-TV in males (13.8 ± 21.5) and females (5.4 ± 6.8) were significantly different (t = 4.620; p < 0.001). CT-DOI also differed significantly (t = 4.621; p < 0.001) between males (14.4 ± 7.4) and females (10.7 ± 4.4). CT-BI was detected in 30.1%, the most common in the alveolar ridge OSCC. T2 tumor status (31.4%) and stage IVA (28.3%) were the most dominant at the time of diagnosis. Metastatic lymph nodes were detected in 41.1%. Conclusion Our findings revealed significant gender-related differences in OSCC imaging features. The predominance of moderate and advanced tumor stages indicates a long time interval to the OSCC diagnosis. PB - Springer T2 - BMC Oral Health T1 - Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study VL - 24 IS - 141 DO - https://doi.org/10.1186/s12903-024-03869-8 ER -
@article{ author = "Janović, Aleksa and Bracanović, Đurđa and Antić, Svetlana and Marković-Vasiljković, Biljana", year = "2024-01-29", abstract = "Background The mortality of oral squamous cell cancer (OSCC) in Serbia increased in the last decade. Recent studies on the Serbian population focused mainly on the epidemiological aspect of OSCC. This study aimed to investigate the demographic and imaging features of OSCC in the Serbian population at the time of diagnosis. Methods We retrospectively analyzed computed tomography (CT) images of 276 patients with OSCC diagnosed between 2017 and 2022. Age, gender, tumor site, tumor volume (CT-TV, in cm3), depth of invasion (CT-DOI, in mm), and bone invasion (CT-BI, in %) were evaluated. TNM status and tumor stage were also analyzed. All parameters were analyzed with appropriate statistical tests. Results The mean age was 62.32 ± 11.39 and 63.25 ± 11.71 for males and females, respectively. Male to female ratio was 1.63:1. The tongue (36.2%), mouth floor (21.0%), and alveolar ridge (19.9%) were the most frequent sites of OSCC. There was a significant gender-related difference in OSCC distribution between oral cavity subsites (Z=-4.225; p < 0.001). Mean values of CT-TV in males (13.8 ± 21.5) and females (5.4 ± 6.8) were significantly different (t = 4.620; p < 0.001). CT-DOI also differed significantly (t = 4.621; p < 0.001) between males (14.4 ± 7.4) and females (10.7 ± 4.4). CT-BI was detected in 30.1%, the most common in the alveolar ridge OSCC. T2 tumor status (31.4%) and stage IVA (28.3%) were the most dominant at the time of diagnosis. Metastatic lymph nodes were detected in 41.1%. Conclusion Our findings revealed significant gender-related differences in OSCC imaging features. The predominance of moderate and advanced tumor stages indicates a long time interval to the OSCC diagnosis.", publisher = "Springer", journal = "BMC Oral Health", title = "Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study", volume = "24", number = "141", doi = "https://doi.org/10.1186/s12903-024-03869-8" }
Janović, A., Bracanović, Đ., Antić, S.,& Marković-Vasiljković, B.. (2024-01-29). Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study. in BMC Oral Health Springer., 24(141). https://doi.org/https://doi.org/10.1186/s12903-024-03869-8
Janović A, Bracanović Đ, Antić S, Marković-Vasiljković B. Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study. in BMC Oral Health. 2024;24(141). doi:https://doi.org/10.1186/s12903-024-03869-8 .
Janović, Aleksa, Bracanović, Đurđa, Antić, Svetlana, Marković-Vasiljković, Biljana, "Demographic and imaging features of oral squamous cell cancer in Serbia: a retrospective cross-sectional study" in BMC Oral Health, 24, no. 141 (2024-01-29), https://doi.org/https://doi.org/10.1186/s12903-024-03869-8 . .