TY  - JOUR
AU  - Popovska, Lidija
AU  - Dimova, Cena
AU  - Evrosimoska, Biljana
AU  - Stojanovska, Vera
AU  - Muratovska, Ilijana
AU  - Ćetenović, Bojana
AU  - Marković, Dejan
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2253
AB  - Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion. The aim of this study was to determine the quantity of interleukin-1β in the tissues of periapical lesions and to analyze its relationships with: lesion size, previous treatments and pathohistological finding of involved teeth. Methods. Periapical tissues were obtained from patients undergoing periapical surgery. Out of all 80 cases included in the study, 24 had no previous endodontic treatment (open lesions), 37 were with endodontic failure (closed lesion) and in 15 cases root canal retreatment was performed few months before the surgery. By excluding four samples, the total of 76 samples, consisted of periapical lesions and the apical part of the tooth root, was collected. Each periapical tissue sample was divided into two equal parts. The one half of each lesion was used for quantification of interleukin-1β in tissue homogenates by the enzyme-linked immunosorbent assay (ELISA) method. The other part of each lesion was used for histopathological evaluation. Results. For each of the tissue homogenates, the quantity of interleukin-1β was measured, and it ranged from 0.6 pg/mg up to 74 pg/mg. There was no significant difference between the symptomatology and amount of interleukin-1β. Statistical data analysis showed a moderate correlation between lesion size and interleukin-1β measured values. The highest levels of interleukin-1β corresponded with chronic lesions in the stages of acute exacerbation and granulomas in early developing stages. Persistant granulomas, scar tissues, non-inflamed cysts and teeth with recently finished endodontic treatments showed a significantly lower level of interleukin-1β. Conclusion. The study results suggest that the differences in quantity of interleukin-1β correlate to lesion progression and phases of development.
AB  - Uvod/Cilj. Periapikalni periodontitis najčešće je prouzrokovan bakterijskom infekcijom unetom putem kanala zubnog korena i periapikalnom destrukcijom kosti koje predstavlja glavno obeležje ovih lezija. Cilj ovog istraživanja bio je da se odredi količina interleukina-1β u uzorcima periapikalnih lezija i da se analizira njihova povezanost sa: veličinom lezija, postojanjem prethodnih endodontskih tretmana i patohistološkim nalazima. Metode. Ispitivani su uzorci periapikalnih lezija sakupljeni tokom periapikalnih operativnih intervencija. Od svih 80 bolesnika uključenih u studiju, 24 su pripadali bolesnicima koji nisu podvrgnuti endodontskom tretmanu pre apikotomije (otvorene lezije), 37 su tretirani kao endodontski neuspeh (zatvorene lezije), a kod 15 bolesnika endodontski retreatman je sproveden nekoliko meseci pre oralno-hirurške intervencije; četiri uzorka su isključena iz studije. Svaki uzorak koji se sastojao od periapikalne lezije i vrha korena zuba podeljen je na dva jednaka dela. Prva polovina svakog uzorka korišćena je za kvantifikaciju interleukina-1β u tkivnom homogenatu metodom enzyme-linked immunosorbent assay (ELISA). Druga polovina uzorka korišćena je za histopatološku analizu. Rezultati. U svakom tkivnom homogenatu izmerena je količina interleukina-1β, čije vrednosti su se kretale od 0,6 do 74 pg/mg. Naši rezultati nisu potvrdili značajnu razliku između simptomatomatičnih i asimptomatičnih slučajeva; dokazano je prisustvo umerene korelacije između veličine lezija i vrednosti interleukina-1β. Najviše vrednosti interleukina-1β potvrđene su u fazama akutnog pogoršanja hroničnih lezija i kod granuloma u ranim razvojnim fazama. Kod starih granuloma, ožiljačnih tkiva, zuba sa nedavno završenim endodontskim retretmanom i neinflamiranih cista, vrednosti interleukina-1β bile su značajno niže. Zaključak. Rezultati istraživanja pokazuju da su razlike u količini interleukina-1β u korelaciji sa progresijom lezija i fazama njihovog razvoja.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Relationship between IL-1β production and endodontic status of human periapical lesions
T1  - Povezanost stvaranja IL-1β i karakteristika humanih periapikalnih lezija
VL  - 74
IS  - 12
SP  - 1134
EP  - 1139
DO  - 10.2298/VSP151228309P
ER  - 

@article{
author = "Popovska, Lidija and Dimova, Cena and Evrosimoska, Biljana and Stojanovska, Vera and Muratovska, Ilijana and Ćetenović, Bojana and Marković, Dejan",
year = "2017",
abstract = "Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion. The aim of this study was to determine the quantity of interleukin-1β in the tissues of periapical lesions and to analyze its relationships with: lesion size, previous treatments and pathohistological finding of involved teeth. Methods. Periapical tissues were obtained from patients undergoing periapical surgery. Out of all 80 cases included in the study, 24 had no previous endodontic treatment (open lesions), 37 were with endodontic failure (closed lesion) and in 15 cases root canal retreatment was performed few months before the surgery. By excluding four samples, the total of 76 samples, consisted of periapical lesions and the apical part of the tooth root, was collected. Each periapical tissue sample was divided into two equal parts. The one half of each lesion was used for quantification of interleukin-1β in tissue homogenates by the enzyme-linked immunosorbent assay (ELISA) method. The other part of each lesion was used for histopathological evaluation. Results. For each of the tissue homogenates, the quantity of interleukin-1β was measured, and it ranged from 0.6 pg/mg up to 74 pg/mg. There was no significant difference between the symptomatology and amount of interleukin-1β. Statistical data analysis showed a moderate correlation between lesion size and interleukin-1β measured values. The highest levels of interleukin-1β corresponded with chronic lesions in the stages of acute exacerbation and granulomas in early developing stages. Persistant granulomas, scar tissues, non-inflamed cysts and teeth with recently finished endodontic treatments showed a significantly lower level of interleukin-1β. Conclusion. The study results suggest that the differences in quantity of interleukin-1β correlate to lesion progression and phases of development., Uvod/Cilj. Periapikalni periodontitis najčešće je prouzrokovan bakterijskom infekcijom unetom putem kanala zubnog korena i periapikalnom destrukcijom kosti koje predstavlja glavno obeležje ovih lezija. Cilj ovog istraživanja bio je da se odredi količina interleukina-1β u uzorcima periapikalnih lezija i da se analizira njihova povezanost sa: veličinom lezija, postojanjem prethodnih endodontskih tretmana i patohistološkim nalazima. Metode. Ispitivani su uzorci periapikalnih lezija sakupljeni tokom periapikalnih operativnih intervencija. Od svih 80 bolesnika uključenih u studiju, 24 su pripadali bolesnicima koji nisu podvrgnuti endodontskom tretmanu pre apikotomije (otvorene lezije), 37 su tretirani kao endodontski neuspeh (zatvorene lezije), a kod 15 bolesnika endodontski retreatman je sproveden nekoliko meseci pre oralno-hirurške intervencije; četiri uzorka su isključena iz studije. Svaki uzorak koji se sastojao od periapikalne lezije i vrha korena zuba podeljen je na dva jednaka dela. Prva polovina svakog uzorka korišćena je za kvantifikaciju interleukina-1β u tkivnom homogenatu metodom enzyme-linked immunosorbent assay (ELISA). Druga polovina uzorka korišćena je za histopatološku analizu. Rezultati. U svakom tkivnom homogenatu izmerena je količina interleukina-1β, čije vrednosti su se kretale od 0,6 do 74 pg/mg. Naši rezultati nisu potvrdili značajnu razliku između simptomatomatičnih i asimptomatičnih slučajeva; dokazano je prisustvo umerene korelacije između veličine lezija i vrednosti interleukina-1β. Najviše vrednosti interleukina-1β potvrđene su u fazama akutnog pogoršanja hroničnih lezija i kod granuloma u ranim razvojnim fazama. Kod starih granuloma, ožiljačnih tkiva, zuba sa nedavno završenim endodontskim retretmanom i neinflamiranih cista, vrednosti interleukina-1β bile su značajno niže. Zaključak. Rezultati istraživanja pokazuju da su razlike u količini interleukina-1β u korelaciji sa progresijom lezija i fazama njihovog razvoja.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Relationship between IL-1β production and endodontic status of human periapical lesions, Povezanost stvaranja IL-1β i karakteristika humanih periapikalnih lezija",
volume = "74",
number = "12",
pages = "1134-1139",
doi = "10.2298/VSP151228309P"
}

Popovska, L., Dimova, C., Evrosimoska, B., Stojanovska, V., Muratovska, I., Ćetenović, B.,& Marković, D.. (2017). Relationship between IL-1β production and endodontic status of human periapical lesions. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 74(12), 1134-1139.
https://doi.org/10.2298/VSP151228309P

Popovska L, Dimova C, Evrosimoska B, Stojanovska V, Muratovska I, Ćetenović B, Marković D. Relationship between IL-1β production and endodontic status of human periapical lesions. in Vojnosanitetski pregled. 2017;74(12):1134-1139.
doi:10.2298/VSP151228309P .

Popovska, Lidija, Dimova, Cena, Evrosimoska, Biljana, Stojanovska, Vera, Muratovska, Ilijana, Ćetenović, Bojana, Marković, Dejan, "Relationship between IL-1β production and endodontic status of human periapical lesions" in Vojnosanitetski pregled, 74, no. 12 (2017):1134-1139,
https://doi.org/10.2298/VSP151228309P . .

TY  - JOUR
AU  - Stojanovska, Vera
AU  - Ivanoff, Chris S.
AU  - Muratovska, Ilijana
AU  - Popovska, Lidija
AU  - Garcia-Godoy, Franklin
AU  - Hottel, Timothy L.
AU  - Marković, Dejan
AU  - Morrow, Brian R.
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2238
AB  - Background/Aim. The longevity of a dental restoration may be predicted to some degree by its adhesive ability, and this, in turn, can be measured by bond strength testing between restorative materials and tooth structure. The aim of this study was to test an innovative joggle lap shearing jig that integrates the tooth and the entire biomechanical unit into testing, to compare the shear bond strengths of Class I occlusal composite restorations in deep cavity preparations lined with Dycal, Dycal LC, conventional glass ionomer or resin-modified glass ionomer. The mode of failure (adhesive, cohesive, mixed) after debonding was determined by stereomicroscopy. Methods. A total of 150 standardized occlusal cavities were prepared and divided into five groups. The group I cavities (n = 30) were coated with adhesive (ExciTE®F) and filled directly with composite (TetricEvoCeram). The group II and III cavities were lined with Dycal (n = 30) or Dycal LC (n = 30) before placing composite. The groups IV and V specimens were based with Fuji IX (n = 30) or Fuji II LC (n = 30). Shear bond strengths were determined with a universal testing machine and fractured bonding sites were analyzed under stereomicroscope. The mean bond strengths were analyzed using one-way ANOVA test (p  lt  0.05) and the means between the groups were analyzed with Student's t-test. Results. The shear bond strength (MPa) of composite restorations in cavities without base (23.91 ± 4.54) was higher than cavities lined with Fuji II LC (17.45 ± 2.74), Fuji IX (8.76 ± 2.57), Dycal LC (13.07 ± 1.84) or Dycal (6.12 ± 1.28). The results using the jogged lap shearing jig were consistent with the literature. Conclusion. The shear bond strength of occlusal composite restorations in deep cavities without liners was greater than cavities lined with Fuji II LC > Fuji IX > Dycal LC > Dycal.
AB  - Uvod/Cilj. Trajnost zubnih nadoknada može se donekle predvideti vstom adhezivne sposobnosti materijala i može se meriti testiranjem snage adhezije restorativnih materijala i zubnih struktura. Cilj ove studije bio je da se da se testira preklapanje spoja koji povezuje zub i biomehaničku jedinicu i da se uporedi jačina veze okluzalnih kompozitnih ispuna postavljenih u duboke kavitete preko podloge od Dycal, Dycal LC, konvencionalnog ili smolom-modifikovanog glas-jonomer cementa. Metode. Ukupno 150 standardizovanih okluzalnih kaviteta bilo je podeljeno u pet grupa (n = 30): I - kaviteti premazani adhezivom (ExciTE®F) i direktno ispunjeni kompozitom (TetricEvoCeram); II i III - kaviteti sa podlogom od Dycal ili Dycal LC pre postavljanja kompozitnog materijala; IV i V - uzorci sa bazom od Fuji IX ili Fuji II LC (n = 30). Jačina vezivne snage određena je pomoću univerzalne mašine, a način neuspeha (adhezivna, kohezivna, mešovita fraktura) određen je stereomikroskopom. Srednje vrednosti su analizirane pomoću ANOVA testa (p  lt  0,05), a značajnost razlika između grupa analizirana je Student-ovim t-testom. Rezultati. Jačina vezivne snage (MPa) kompozitnih ispuna u kavitetima bez podloge (23,91 ± 4,54) bila je veća u poređenju sa ispunima postavljenim preko Fuji II LC (17,45 ± 2,74), Fuji IX (8,76 ± 2,57), Dycal LC (13,07 ± 1,84) ili Dycal (6.12 ± 1.28). Zaključak. Smicanje ili pomaknuće okluzalnih kompozitnih ispuna u dubokim kavitetima bez lajnera je veće nego u kavitetima postavljenim preko Fuji II LC > Fuji IX > Dycal LC > Dycal.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Joggle lap shear testing of deep occlusal composite restorations lined with Dycal, Dycal LC, conventional or resin-modified glass ionomer
T1  - Testiranje spojnog smicanja dubokih okluzalnih kompozitnih restauracija postavljenih preko podloge od Dycal, Dycal LC, konvencionalnog ili smolom modifikovanog glas-jonomer cementa
VL  - 74
IS  - 5
SP  - 410
EP  - 419
DO  - 10.2298/VSP150816226S
ER  - 

@article{
author = "Stojanovska, Vera and Ivanoff, Chris S. and Muratovska, Ilijana and Popovska, Lidija and Garcia-Godoy, Franklin and Hottel, Timothy L. and Marković, Dejan and Morrow, Brian R.",
year = "2017",
abstract = "Background/Aim. The longevity of a dental restoration may be predicted to some degree by its adhesive ability, and this, in turn, can be measured by bond strength testing between restorative materials and tooth structure. The aim of this study was to test an innovative joggle lap shearing jig that integrates the tooth and the entire biomechanical unit into testing, to compare the shear bond strengths of Class I occlusal composite restorations in deep cavity preparations lined with Dycal, Dycal LC, conventional glass ionomer or resin-modified glass ionomer. The mode of failure (adhesive, cohesive, mixed) after debonding was determined by stereomicroscopy. Methods. A total of 150 standardized occlusal cavities were prepared and divided into five groups. The group I cavities (n = 30) were coated with adhesive (ExciTE®F) and filled directly with composite (TetricEvoCeram). The group II and III cavities were lined with Dycal (n = 30) or Dycal LC (n = 30) before placing composite. The groups IV and V specimens were based with Fuji IX (n = 30) or Fuji II LC (n = 30). Shear bond strengths were determined with a universal testing machine and fractured bonding sites were analyzed under stereomicroscope. The mean bond strengths were analyzed using one-way ANOVA test (p  lt  0.05) and the means between the groups were analyzed with Student's t-test. Results. The shear bond strength (MPa) of composite restorations in cavities without base (23.91 ± 4.54) was higher than cavities lined with Fuji II LC (17.45 ± 2.74), Fuji IX (8.76 ± 2.57), Dycal LC (13.07 ± 1.84) or Dycal (6.12 ± 1.28). The results using the jogged lap shearing jig were consistent with the literature. Conclusion. The shear bond strength of occlusal composite restorations in deep cavities without liners was greater than cavities lined with Fuji II LC > Fuji IX > Dycal LC > Dycal., Uvod/Cilj. Trajnost zubnih nadoknada može se donekle predvideti vstom adhezivne sposobnosti materijala i može se meriti testiranjem snage adhezije restorativnih materijala i zubnih struktura. Cilj ove studije bio je da se da se testira preklapanje spoja koji povezuje zub i biomehaničku jedinicu i da se uporedi jačina veze okluzalnih kompozitnih ispuna postavljenih u duboke kavitete preko podloge od Dycal, Dycal LC, konvencionalnog ili smolom-modifikovanog glas-jonomer cementa. Metode. Ukupno 150 standardizovanih okluzalnih kaviteta bilo je podeljeno u pet grupa (n = 30): I - kaviteti premazani adhezivom (ExciTE®F) i direktno ispunjeni kompozitom (TetricEvoCeram); II i III - kaviteti sa podlogom od Dycal ili Dycal LC pre postavljanja kompozitnog materijala; IV i V - uzorci sa bazom od Fuji IX ili Fuji II LC (n = 30). Jačina vezivne snage određena je pomoću univerzalne mašine, a način neuspeha (adhezivna, kohezivna, mešovita fraktura) određen je stereomikroskopom. Srednje vrednosti su analizirane pomoću ANOVA testa (p  lt  0,05), a značajnost razlika između grupa analizirana je Student-ovim t-testom. Rezultati. Jačina vezivne snage (MPa) kompozitnih ispuna u kavitetima bez podloge (23,91 ± 4,54) bila je veća u poređenju sa ispunima postavljenim preko Fuji II LC (17,45 ± 2,74), Fuji IX (8,76 ± 2,57), Dycal LC (13,07 ± 1,84) ili Dycal (6.12 ± 1.28). Zaključak. Smicanje ili pomaknuće okluzalnih kompozitnih ispuna u dubokim kavitetima bez lajnera je veće nego u kavitetima postavljenim preko Fuji II LC > Fuji IX > Dycal LC > Dycal.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Joggle lap shear testing of deep occlusal composite restorations lined with Dycal, Dycal LC, conventional or resin-modified glass ionomer, Testiranje spojnog smicanja dubokih okluzalnih kompozitnih restauracija postavljenih preko podloge od Dycal, Dycal LC, konvencionalnog ili smolom modifikovanog glas-jonomer cementa",
volume = "74",
number = "5",
pages = "410-419",
doi = "10.2298/VSP150816226S"
}

Stojanovska, V., Ivanoff, C. S., Muratovska, I., Popovska, L., Garcia-Godoy, F., Hottel, T. L., Marković, D.,& Morrow, B. R.. (2017). Joggle lap shear testing of deep occlusal composite restorations lined with Dycal, Dycal LC, conventional or resin-modified glass ionomer. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 74(5), 410-419.
https://doi.org/10.2298/VSP150816226S

Stojanovska V, Ivanoff CS, Muratovska I, Popovska L, Garcia-Godoy F, Hottel TL, Marković D, Morrow BR. Joggle lap shear testing of deep occlusal composite restorations lined with Dycal, Dycal LC, conventional or resin-modified glass ionomer. in Vojnosanitetski pregled. 2017;74(5):410-419.
doi:10.2298/VSP150816226S .

Stojanovska, Vera, Ivanoff, Chris S., Muratovska, Ilijana, Popovska, Lidija, Garcia-Godoy, Franklin, Hottel, Timothy L., Marković, Dejan, Morrow, Brian R., "Joggle lap shear testing of deep occlusal composite restorations lined with Dycal, Dycal LC, conventional or resin-modified glass ionomer" in Vojnosanitetski pregled, 74, no. 5 (2017):410-419,
https://doi.org/10.2298/VSP150816226S . .