Ćalasan, Dejan

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  • Ćalasan, Dejan (9)
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Arterial supply of the trigeminal ganglion, a micromorphological study

Cetković, M.; Stimec, Bojan V.; Mucić, Dinka; Dožić, Aleksandra; Ćetković, Dejan; Reci, V; Cerkezi, S.; Ćalasan, Dejan; Milisavljević, M.; Bexheti, S.

(Via Medica, Gdansk, 2020)

TY  - JOUR
AU  - Cetković, M.
AU  - Stimec, Bojan V.
AU  - Mucić, Dinka
AU  - Dožić, Aleksandra
AU  - Ćetković, Dejan
AU  - Reci, V
AU  - Cerkezi, S.
AU  - Ćalasan, Dejan
AU  - Milisavljević, M.
AU  - Bexheti, S.
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2498
AB  - Background: In this study, we explored the specific microanatomical properties of the trigeminal ganglion (TG) blood supply and its close neurovascular relationships with the surrounding vessels. Possible clinical implications have been discussed. Materials and methods: The internal carotid and maxillary arteries of 25 adult and 4 foetal heads were injected with a 10% mixture of India ink and gelatin, and their TGs subsequently underwent microdissection, observation and morphometry under a stereoscopic microscope. Results: The number of trigeminal arteries varied between 3 and 5 (mean 3.34), originating from 2 or 3 of the following sources: the inferolateral trunk (ILT) (100%), the meningohypophyseal trunk (MHT) (100%), and from the middle meningeal artery (MMA) (92%). In total, the mean diameter of the trigeminal branches was 0.222 mm. The trigeminal branch of the ILT supplied medial and middle parts of the TG, the branch of the MHT supplied the medial part of the TG, and the branch of the MMA supplied the lateral part of the TG. Additional arteries for the TG emerged from the dural vascular plexus and the vascular network of the plexal segment of the trigeminal nerve. Uniform and specific intraganglionic dense capillary network was observed for each sensory trigeminal neuron. Conclusions: The reported features of the TG vasculature could be implied in a safer setting for surgical approach to the skull base, in relation to the surrounding structures. The morphometric data on TG vasculature provide anatomical basis for better understanding the complex TG blood supply from the internal and external carotid arteries.
PB  - Via Medica, Gdansk
T2  - Folia Morphologica
T1  - Arterial supply of the trigeminal ganglion, a micromorphological study
VL  - 79
IS  - 1
SP  - 58
EP  - 64
DO  - 10.5603/FM.a2019.0062
ER  - 
@article{
author = "Cetković, M. and Stimec, Bojan V. and Mucić, Dinka and Dožić, Aleksandra and Ćetković, Dejan and Reci, V and Cerkezi, S. and Ćalasan, Dejan and Milisavljević, M. and Bexheti, S.",
year = "2020",
abstract = "Background: In this study, we explored the specific microanatomical properties of the trigeminal ganglion (TG) blood supply and its close neurovascular relationships with the surrounding vessels. Possible clinical implications have been discussed. Materials and methods: The internal carotid and maxillary arteries of 25 adult and 4 foetal heads were injected with a 10% mixture of India ink and gelatin, and their TGs subsequently underwent microdissection, observation and morphometry under a stereoscopic microscope. Results: The number of trigeminal arteries varied between 3 and 5 (mean 3.34), originating from 2 or 3 of the following sources: the inferolateral trunk (ILT) (100%), the meningohypophyseal trunk (MHT) (100%), and from the middle meningeal artery (MMA) (92%). In total, the mean diameter of the trigeminal branches was 0.222 mm. The trigeminal branch of the ILT supplied medial and middle parts of the TG, the branch of the MHT supplied the medial part of the TG, and the branch of the MMA supplied the lateral part of the TG. Additional arteries for the TG emerged from the dural vascular plexus and the vascular network of the plexal segment of the trigeminal nerve. Uniform and specific intraganglionic dense capillary network was observed for each sensory trigeminal neuron. Conclusions: The reported features of the TG vasculature could be implied in a safer setting for surgical approach to the skull base, in relation to the surrounding structures. The morphometric data on TG vasculature provide anatomical basis for better understanding the complex TG blood supply from the internal and external carotid arteries.",
publisher = "Via Medica, Gdansk",
journal = "Folia Morphologica",
title = "Arterial supply of the trigeminal ganglion, a micromorphological study",
volume = "79",
number = "1",
pages = "58-64",
doi = "10.5603/FM.a2019.0062"
}
Cetković, M., Stimec, B. V., Mucić, D., Dožić, A., Ćetković, D., Reci, V., Cerkezi, S., Ćalasan, D., Milisavljević, M.,& Bexheti, S.. (2020). Arterial supply of the trigeminal ganglion, a micromorphological study. in Folia Morphologica
Via Medica, Gdansk., 79(1), 58-64.
https://doi.org/10.5603/FM.a2019.0062
Cetković M, Stimec BV, Mucić D, Dožić A, Ćetković D, Reci V, Cerkezi S, Ćalasan D, Milisavljević M, Bexheti S. Arterial supply of the trigeminal ganglion, a micromorphological study. in Folia Morphologica. 2020;79(1):58-64.
doi:10.5603/FM.a2019.0062 .
Cetković, M., Stimec, Bojan V., Mucić, Dinka, Dožić, Aleksandra, Ćetković, Dejan, Reci, V, Cerkezi, S., Ćalasan, Dejan, Milisavljević, M., Bexheti, S., "Arterial supply of the trigeminal ganglion, a micromorphological study" in Folia Morphologica, 79, no. 1 (2020):58-64,
https://doi.org/10.5603/FM.a2019.0062 . .
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Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study

Ćetković, Dejan; Milić, Marija; Biočanin, Vladimir; Brajić, Ivana; Ćalasan, Dejan; Radović, Katarina; Živković, Rade; Brković, Božidar

(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2019)

TY  - JOUR
AU  - Ćetković, Dejan
AU  - Milić, Marija
AU  - Biočanin, Vladimir
AU  - Brajić, Ivana
AU  - Ćalasan, Dejan
AU  - Radović, Katarina
AU  - Živković, Rade
AU  - Brković, Božidar
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2448
AB  - Bacground/Aim. The efficient dental anesthesia, which is related to the clinically adequate depth, duration and the width of anesthetic field, is an important prerequisite for successful dental treatment. The aim of this study was to investigate and compare the pulpal anesthesia and cardiovascular parameters after the anterior middle superior alveolar (AMSA) nerve block with 4% articaine with epinephrine administered by conventional cartridge-syringe and computer-controlled local anesthetic delivery system (CCLADS). Methods. This controlled double-blind cross-over randomized clinical study included 38 healthy volunteers. Efficacy of pulpal anesthesia after the AMSA nerve block was evaluated by measuring a success rate, onset and duration of pulpal anesthesia, using an electrical pulp tester. The parameters of cardiovascular function (systolic and diastolic blood pressure, heart rate) were monitored noninvasively. Results. Successful pulpal anesthesia of all tested teeth was obtained in 57.9% participants with CCLADS and in 44.7% participants with conventional syringe. The onset time was not significantly different between two investigated groups. The pulpal anesthesia duration was not significantly different neither within nor between investigated groups. The systolic and diastolic blood pressures were significantly decreased in both investigated groups, in comparison with the baseline values. Heart rate significantly decreased within CCLADS from 10th to 30th minute when compared to baseline. Conclusion. The efficacy of pulpal anesthesia and safety of cardiovascular profile of 0.6 mL of articaine with epinephrine (1:100.000) delivered with CCLADS were improved in comparison to the conventional syringe delivery. Significant changes of cardiovascular function were not observed.
AB  - Uvod/Cilj. Efikasna zubna anestezija u pogledu klinički adekvatne dubine, trajanja i širine anestetičkog polja je važan preduslov za uspešno zubno lečenje. Cilj rada bio je ispitivanje i upoređivanje parametra anestezije zubne pulpe i kardiovaskularnih parametra posle gornje prednje i srednje alveolarne (AMSA) sprovodne anestezije postignute 4% artikainom sa epinefrinom, primenom standardne karpulbrizgalice i kompjuterski kontrolisanog sistema za primenu anestetičkog rastvora (CCLADS). Metode. U ovom randomizovanom, prospektivnom, kontrolisanom, dvostruko slepom ukrštenom kliničkom istraživanju učestvovalo je 38 ispitanika. Kvalitet anestezije zubne pulpe posle AMSA anestezije praćen je na osnovu uspešnosti, latentnog perioda i trajanja anestezije zubne pulpe, primenom električnog pulp-testera. Parametri kardiovaskularne funkcije (sistolni i dijastolni krvni pritisak, srčana frekvencija) praćeni su neinvazivno, primenom aparata za monitoring. Rezultati. Uspešna anestezija zubne pulpe svih ispitivanih zuba bila je prisutna kod 57,9% ispitanika posle kod CCLADS i kod 44,7% ispitanika posle primene standardne karpul-brizgalice. Latentni period i trajanje anestezije zubne pulpe nisu se značajno razlikovali između ispitivanih grupa. Sistolni i dijastolni pritisak bili su značajno sniženi u praćenim vremenskim intervalima u odnosu na početne vrednosti. Srčana frekvencija je bila značajno snižena kod CCLADS grupe od 10 do 30 minuta u odnosu na početne vrednosti. Zaključak. Kontrolisanom kompjuterizovanom primenom (CCLADS) 0,6 mL 4% artikaina sa epinefrinom (1:100,000) za AMSA sprovodnu anesteziju, postignut je bolji kvalitet anestezije zubne pulpe u odnosu na primenu artikaina sa epinefrinom standardnom karpul brizgalicom. Nisu uočene bitne promene funkcija kardiovaskularnog sistema.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study
T1  - Efikasnost i sigurnost 4% artikaina sa epinefrinom za gornji prednji i srednji alveolarni nervni blok primenom kompjuterski kontrolisanog sistema i standardnog pristupa za primenu anestetičkog rastvora - prospektivna, randomizovana, kontrolisana, dvosturko slepa, ukrštena klinička studija
VL  - 76
IS  - 10
SP  - 1045
EP  - 1053
DO  - 10.2298/VSP170511013C
ER  - 
@article{
author = "Ćetković, Dejan and Milić, Marija and Biočanin, Vladimir and Brajić, Ivana and Ćalasan, Dejan and Radović, Katarina and Živković, Rade and Brković, Božidar",
year = "2019",
abstract = "Bacground/Aim. The efficient dental anesthesia, which is related to the clinically adequate depth, duration and the width of anesthetic field, is an important prerequisite for successful dental treatment. The aim of this study was to investigate and compare the pulpal anesthesia and cardiovascular parameters after the anterior middle superior alveolar (AMSA) nerve block with 4% articaine with epinephrine administered by conventional cartridge-syringe and computer-controlled local anesthetic delivery system (CCLADS). Methods. This controlled double-blind cross-over randomized clinical study included 38 healthy volunteers. Efficacy of pulpal anesthesia after the AMSA nerve block was evaluated by measuring a success rate, onset and duration of pulpal anesthesia, using an electrical pulp tester. The parameters of cardiovascular function (systolic and diastolic blood pressure, heart rate) were monitored noninvasively. Results. Successful pulpal anesthesia of all tested teeth was obtained in 57.9% participants with CCLADS and in 44.7% participants with conventional syringe. The onset time was not significantly different between two investigated groups. The pulpal anesthesia duration was not significantly different neither within nor between investigated groups. The systolic and diastolic blood pressures were significantly decreased in both investigated groups, in comparison with the baseline values. Heart rate significantly decreased within CCLADS from 10th to 30th minute when compared to baseline. Conclusion. The efficacy of pulpal anesthesia and safety of cardiovascular profile of 0.6 mL of articaine with epinephrine (1:100.000) delivered with CCLADS were improved in comparison to the conventional syringe delivery. Significant changes of cardiovascular function were not observed., Uvod/Cilj. Efikasna zubna anestezija u pogledu klinički adekvatne dubine, trajanja i širine anestetičkog polja je važan preduslov za uspešno zubno lečenje. Cilj rada bio je ispitivanje i upoređivanje parametra anestezije zubne pulpe i kardiovaskularnih parametra posle gornje prednje i srednje alveolarne (AMSA) sprovodne anestezije postignute 4% artikainom sa epinefrinom, primenom standardne karpulbrizgalice i kompjuterski kontrolisanog sistema za primenu anestetičkog rastvora (CCLADS). Metode. U ovom randomizovanom, prospektivnom, kontrolisanom, dvostruko slepom ukrštenom kliničkom istraživanju učestvovalo je 38 ispitanika. Kvalitet anestezije zubne pulpe posle AMSA anestezije praćen je na osnovu uspešnosti, latentnog perioda i trajanja anestezije zubne pulpe, primenom električnog pulp-testera. Parametri kardiovaskularne funkcije (sistolni i dijastolni krvni pritisak, srčana frekvencija) praćeni su neinvazivno, primenom aparata za monitoring. Rezultati. Uspešna anestezija zubne pulpe svih ispitivanih zuba bila je prisutna kod 57,9% ispitanika posle kod CCLADS i kod 44,7% ispitanika posle primene standardne karpul-brizgalice. Latentni period i trajanje anestezije zubne pulpe nisu se značajno razlikovali između ispitivanih grupa. Sistolni i dijastolni pritisak bili su značajno sniženi u praćenim vremenskim intervalima u odnosu na početne vrednosti. Srčana frekvencija je bila značajno snižena kod CCLADS grupe od 10 do 30 minuta u odnosu na početne vrednosti. Zaključak. Kontrolisanom kompjuterizovanom primenom (CCLADS) 0,6 mL 4% artikaina sa epinefrinom (1:100,000) za AMSA sprovodnu anesteziju, postignut je bolji kvalitet anestezije zubne pulpe u odnosu na primenu artikaina sa epinefrinom standardnom karpul brizgalicom. Nisu uočene bitne promene funkcija kardiovaskularnog sistema.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study, Efikasnost i sigurnost 4% artikaina sa epinefrinom za gornji prednji i srednji alveolarni nervni blok primenom kompjuterski kontrolisanog sistema i standardnog pristupa za primenu anestetičkog rastvora - prospektivna, randomizovana, kontrolisana, dvosturko slepa, ukrštena klinička studija",
volume = "76",
number = "10",
pages = "1045-1053",
doi = "10.2298/VSP170511013C"
}
Ćetković, D., Milić, M., Biočanin, V., Brajić, I., Ćalasan, D., Radović, K., Živković, R.,& Brković, B.. (2019). Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(10), 1045-1053.
https://doi.org/10.2298/VSP170511013C
Ćetković D, Milić M, Biočanin V, Brajić I, Ćalasan D, Radović K, Živković R, Brković B. Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study. in Vojnosanitetski pregled. 2019;76(10):1045-1053.
doi:10.2298/VSP170511013C .
Ćetković, Dejan, Milić, Marija, Biočanin, Vladimir, Brajić, Ivana, Ćalasan, Dejan, Radović, Katarina, Živković, Rade, Brković, Božidar, "Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study" in Vojnosanitetski pregled, 76, no. 10 (2019):1045-1053,
https://doi.org/10.2298/VSP170511013C . .
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Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study

Brković, Božidar; Andrić, Miroslav; Ćalasan, Dejan; Milić, Marija; Stepić, Jelena; Vučetić, Milan; Brajković, Denis; Todorović, Ljubomir

(Springer Heidelberg, Heidelberg, 2017)

TY  - JOUR
AU  - Brković, Božidar
AU  - Andrić, Miroslav
AU  - Ćalasan, Dejan
AU  - Milić, Marija
AU  - Stepić, Jelena
AU  - Vučetić, Milan
AU  - Brajković, Denis
AU  - Todorović, Ljubomir
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2241
AB  - The purpose of this study was to investigate postoperative analgesic effect of ropivacaine administered as main or supplemental injection for the inferior alveolar nerve block (IANB) in patients undergoing lower third molar surgery. The double-blind randomized study comprised 72 healthy patients. All patients received two blocks, the IANB for surgical procedure + IANB after surgery for postoperative pain control, and were divided into three groups: (1) 2 % lidocaine/epinephrine + 1 % ropivacaine, (2) 2 % lidocaine/epinephrine + saline, and (3) 1 % ropivacaine + saline. The occurrence of postoperative pain, pain intensity and analgesic requirements were recorded. Data were statistically analyzed using chi-square, Fisher, and Kruskal-Wallis tests and analysis of variance (ANOVA) with Bonferroni and Tukey correction. Ropivacaine was more successful than lidocaine/epinephrine in obtaining duration of postoperative analgesia, reduction of pain, and analgesic requirements whether ropivacaine was used for surgical block or administered as a supplemental injection after surgery. Ropivacaine (1 %, 2 ml) resulted in effective postoperative analgesia after lower third molar surgery. Since pain control related to third molar surgery requires the effective surgical anesthesia and postoperative analgesia, the use of 1 % ropivacaine could be clinically relevant in a selection of appropriate pain control regimen for both surgical procedure and early postsurgical treatment.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study
VL  - 21
IS  - 3
SP  - 779
EP  - 785
DO  - 10.1007/s00784-016-1831-2
ER  - 
@article{
author = "Brković, Božidar and Andrić, Miroslav and Ćalasan, Dejan and Milić, Marija and Stepić, Jelena and Vučetić, Milan and Brajković, Denis and Todorović, Ljubomir",
year = "2017",
abstract = "The purpose of this study was to investigate postoperative analgesic effect of ropivacaine administered as main or supplemental injection for the inferior alveolar nerve block (IANB) in patients undergoing lower third molar surgery. The double-blind randomized study comprised 72 healthy patients. All patients received two blocks, the IANB for surgical procedure + IANB after surgery for postoperative pain control, and were divided into three groups: (1) 2 % lidocaine/epinephrine + 1 % ropivacaine, (2) 2 % lidocaine/epinephrine + saline, and (3) 1 % ropivacaine + saline. The occurrence of postoperative pain, pain intensity and analgesic requirements were recorded. Data were statistically analyzed using chi-square, Fisher, and Kruskal-Wallis tests and analysis of variance (ANOVA) with Bonferroni and Tukey correction. Ropivacaine was more successful than lidocaine/epinephrine in obtaining duration of postoperative analgesia, reduction of pain, and analgesic requirements whether ropivacaine was used for surgical block or administered as a supplemental injection after surgery. Ropivacaine (1 %, 2 ml) resulted in effective postoperative analgesia after lower third molar surgery. Since pain control related to third molar surgery requires the effective surgical anesthesia and postoperative analgesia, the use of 1 % ropivacaine could be clinically relevant in a selection of appropriate pain control regimen for both surgical procedure and early postsurgical treatment.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study",
volume = "21",
number = "3",
pages = "779-785",
doi = "10.1007/s00784-016-1831-2"
}
Brković, B., Andrić, M., Ćalasan, D., Milić, M., Stepić, J., Vučetić, M., Brajković, D.,& Todorović, L.. (2017). Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 21(3), 779-785.
https://doi.org/10.1007/s00784-016-1831-2
Brković B, Andrić M, Ćalasan D, Milić M, Stepić J, Vučetić M, Brajković D, Todorović L. Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study. in Clinical Oral Investigations. 2017;21(3):779-785.
doi:10.1007/s00784-016-1831-2 .
Brković, Božidar, Andrić, Miroslav, Ćalasan, Dejan, Milić, Marija, Stepić, Jelena, Vučetić, Milan, Brajković, Denis, Todorović, Ljubomir, "Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study" in Clinical Oral Investigations, 21, no. 3 (2017):779-785,
https://doi.org/10.1007/s00784-016-1831-2 . .
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21

Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report

Biočanin, Vladimir; Milić, Marija; Vučetić, Milan; Baćević, Miljana; Vasović, Dina; Živadinović, Milka; Ćetković, Dejan; Ćalasan, Dejan; Brković, Božidar

(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2016)

TY  - JOUR
AU  - Biočanin, Vladimir
AU  - Milić, Marija
AU  - Vučetić, Milan
AU  - Baćević, Miljana
AU  - Vasović, Dina
AU  - Živadinović, Milka
AU  - Ćetković, Dejan
AU  - Ćalasan, Dejan
AU  - Brković, Božidar
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2073
AB  - Introduction. The material used for root-end filling has to be biocompatible with adjacent periapical tissue and to stimulate its regenerative processes. Tricalcium silicate cement (TSC), as a new dental material, shows good sealing properties with dentin, high compression strengths and better marginal adaptation than commonly used root-end filling materials. Although optimal postoperative healing of periapical tissues is mainly influenced by characteristics of end-root material used, it could sometimes be affected by the influence of systemic diseases, such as diabetes mellitus (DM). Case report. We presented apical healing of the upper central incisor, retrofilled with TSC, in a diabetic patient (type 2 DM) with peripheral neuropathy. Standard root-end resection of upper central incisor was accompanied by retropreparation using ultrasonic retrotips to the depth of 3 mm and retrofilling with TSC. Postoperatively, the surgical wound healed uneventfully. However, the patient reported undefined dull pain in the operated area that could possibly be attributed to undiagnosed intraoral diabetic peripheral neuropathy, what was evaluated clinically. Conclusion. Although TSC presents a suitable material for apical root-end filling in the treatment of chronic periradicular lesions a possible presence of systemic diseases, like type 2 DM, has to be considered in the treatment outcome estimation.
AB  - Uvod. Materijal koji se koristi za retrogradnu opturaciju kanala korena trebalo bi da bude biokompatibilan sa okolnim periapeksnim tkivom i da stimuliše procese njegove regeneracije. Trikalcijum silikatni cement (TSC), kao novi dentalni materijal, pokazuje dobro zaptivanje, visoku kompresivnu snagu i bolju ivičnu adaptaciju u odnosu na standardno korišćene materijale za retroopturaciju. Iako postoperativno zarastanje periapikalnog tkiva najviše zavisi od karakteristika materijala za retroopturaciju, ponekad na uspeh zarastanja može uticati i prisustvo neke sistemske bolesti kao što je dijabetes melitus (DM). Prikaz bolesnika. Prikazali smo apikalno zarastanje u predelu gornjeg centralnog sekutića, nakon retroopturacije sa TSC, kod bolesnika sa DM tipa 2 i prisutnom perifernom neuropatijom. Standardna resekcija korena gornjeg centralnog sekutića bila je urađena retropreparacijom ultrazvučnim nastavcima do dubine od 3 mm i retrogradnom opturacijom sa TSC. Zarastanje postoperativne regije bilo je u fiziološkim granicama. Bolesnik se, međutim, žalio na nedefinisan, tup bol u predelu operisane regije koji je verovatno bio povezan sa nedijagnostikovanom intraoralnom dijabetičnom perifernom neuropatijom, što je potvrđeno kliničkim nalazom. Zaključak. Iako TSC predstavlja pogodan materijal za retrogradnu opturaciju kanala korena zuba u lečenju hroničnih periradikularnih lezija, u proceni ishoda lečenja treba imati u vidu i moguće prisustvo perifernih manfestacija sistemskih bolesti kao što je DM tipa 2.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report
T1  - Punjenje kanala korena cementom na bazi trikalcijum-silikata kod bolesnika sa dijabetesom melitusom
VL  - 73
IS  - 12
SP  - 1173
EP  - 1177
DO  - 10.2298/VSP150606137B
ER  - 
@article{
author = "Biočanin, Vladimir and Milić, Marija and Vučetić, Milan and Baćević, Miljana and Vasović, Dina and Živadinović, Milka and Ćetković, Dejan and Ćalasan, Dejan and Brković, Božidar",
year = "2016",
abstract = "Introduction. The material used for root-end filling has to be biocompatible with adjacent periapical tissue and to stimulate its regenerative processes. Tricalcium silicate cement (TSC), as a new dental material, shows good sealing properties with dentin, high compression strengths and better marginal adaptation than commonly used root-end filling materials. Although optimal postoperative healing of periapical tissues is mainly influenced by characteristics of end-root material used, it could sometimes be affected by the influence of systemic diseases, such as diabetes mellitus (DM). Case report. We presented apical healing of the upper central incisor, retrofilled with TSC, in a diabetic patient (type 2 DM) with peripheral neuropathy. Standard root-end resection of upper central incisor was accompanied by retropreparation using ultrasonic retrotips to the depth of 3 mm and retrofilling with TSC. Postoperatively, the surgical wound healed uneventfully. However, the patient reported undefined dull pain in the operated area that could possibly be attributed to undiagnosed intraoral diabetic peripheral neuropathy, what was evaluated clinically. Conclusion. Although TSC presents a suitable material for apical root-end filling in the treatment of chronic periradicular lesions a possible presence of systemic diseases, like type 2 DM, has to be considered in the treatment outcome estimation., Uvod. Materijal koji se koristi za retrogradnu opturaciju kanala korena trebalo bi da bude biokompatibilan sa okolnim periapeksnim tkivom i da stimuliše procese njegove regeneracije. Trikalcijum silikatni cement (TSC), kao novi dentalni materijal, pokazuje dobro zaptivanje, visoku kompresivnu snagu i bolju ivičnu adaptaciju u odnosu na standardno korišćene materijale za retroopturaciju. Iako postoperativno zarastanje periapikalnog tkiva najviše zavisi od karakteristika materijala za retroopturaciju, ponekad na uspeh zarastanja može uticati i prisustvo neke sistemske bolesti kao što je dijabetes melitus (DM). Prikaz bolesnika. Prikazali smo apikalno zarastanje u predelu gornjeg centralnog sekutića, nakon retroopturacije sa TSC, kod bolesnika sa DM tipa 2 i prisutnom perifernom neuropatijom. Standardna resekcija korena gornjeg centralnog sekutića bila je urađena retropreparacijom ultrazvučnim nastavcima do dubine od 3 mm i retrogradnom opturacijom sa TSC. Zarastanje postoperativne regije bilo je u fiziološkim granicama. Bolesnik se, međutim, žalio na nedefinisan, tup bol u predelu operisane regije koji je verovatno bio povezan sa nedijagnostikovanom intraoralnom dijabetičnom perifernom neuropatijom, što je potvrđeno kliničkim nalazom. Zaključak. Iako TSC predstavlja pogodan materijal za retrogradnu opturaciju kanala korena zuba u lečenju hroničnih periradikularnih lezija, u proceni ishoda lečenja treba imati u vidu i moguće prisustvo perifernih manfestacija sistemskih bolesti kao što je DM tipa 2.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report, Punjenje kanala korena cementom na bazi trikalcijum-silikata kod bolesnika sa dijabetesom melitusom",
volume = "73",
number = "12",
pages = "1173-1177",
doi = "10.2298/VSP150606137B"
}
Biočanin, V., Milić, M., Vučetić, M., Baćević, M., Vasović, D., Živadinović, M., Ćetković, D., Ćalasan, D.,& Brković, B.. (2016). Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 73(12), 1173-1177.
https://doi.org/10.2298/VSP150606137B
Biočanin V, Milić M, Vučetić M, Baćević M, Vasović D, Živadinović M, Ćetković D, Ćalasan D, Brković B. Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report. in Vojnosanitetski pregled. 2016;73(12):1173-1177.
doi:10.2298/VSP150606137B .
Biočanin, Vladimir, Milić, Marija, Vučetić, Milan, Baćević, Miljana, Vasović, Dina, Živadinović, Milka, Ćetković, Dejan, Ćalasan, Dejan, Brković, Božidar, "Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report" in Vojnosanitetski pregled, 73, no. 12 (2016):1173-1177,
https://doi.org/10.2298/VSP150606137B . .

Histomorphometric evaluation of bone regeneration using autogenous bone and beta-tricalcium phosphate in diabetic rabbits

Živadinović, Milka; Andrić, Miroslav; Milošević, Verica; Manojlović-Stojanoski, Milica; Prokić, Branislav; Prokić, Bogomir; Dimić, Aleksandar; Ćalasan, Dejan; Brković, Božidar

(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2016)

TY  - JOUR
AU  - Živadinović, Milka
AU  - Andrić, Miroslav
AU  - Milošević, Verica
AU  - Manojlović-Stojanoski, Milica
AU  - Prokić, Branislav
AU  - Prokić, Bogomir
AU  - Dimić, Aleksandar
AU  - Ćalasan, Dejan
AU  - Brković, Božidar
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2082
AB  - Background/Aim. The mechanism of impaired bone healing in diabetes mellitus includes different tissue and cellular level activities due to micro- and macrovascular changes. As a chronic metabolic disease with vascular complications, diabetes affects a process of bone regeneration as well. The therapeutic approach in bone regeneration is based on the use of osteoinductive autogenous grafts as well as osteoconductive synthetic material, like a β-tricalcium phosphate. The aim of the study was to determine the quality and quantity of new bone formation after the use of autogenous bone and β-tricalcium phosphate in the model of calvarial critical-sized defect in rabbits with induced diabetes mellitus type I. Methods. The study included eight 4-month-old Chincilla rabbits with alloxan-induced diabetes mellitus type I. In all animals, there were surgically created two calvarial bilateral defects (diameter 12 mm), which were grafted with autogenous bone and β-tricalcium phosphate (n = 4) or served as unfilled controls (n = 4). After 4 weeks of healing, animals were sacrificed and calvarial bone blocks were taken for histologic and histomorphometric analysis. Beside descriptive histologic evaluation, the percentage of new bone formation, connective tissue and residual graft were calculated. All parameters were statistically evaluated by Friedman Test and post hock Wilcoxon Singed Ranks Test with a significance of p  lt  0.05. Results. Histology revealed active new bone formation peripherally with centrally located connective tissue, newly formed woven bone and well incorporated residual grafts in all treated defects. Control samples showed no bone bridging of defects. There was a significantly more new bone in autogeonous graft (53%) compared with β-tricalcium phosphate (30%), (p  lt  0.030) and control (7%), (p  lt  0.000) groups. A significant difference was also recorded between β-tricalcium phosphate and control groups (p  lt  0.008). Conclusion. In the present study on the rabbit grafting model with induced diabetes mellitus type I, the effective bone regeneration of critical bone defects was obtained using autogenous bone graft.
AB  - Uvod/Cilj. Mehanizam otežanog zarastanja tkiva kod dijabetesa melitusa zasnovan je na različitim promenama funkcije na tkivnom i ćelijskom nivou, usled prisutnih mikro- i makrovaskularnih promena. Kao hronično metaboličko oboljenje sa vaskularnim komplikacijama, dijabetes melitus zahvata i proces koštane regeneracije. Terapijski postupci u okviru regeneracije kosti obuhvataju primenu autotransplantata sa oseoinduktivnim delovanjem i sintetskih osteokonduktivnih materijala, kao što je i β-trikalcijum fosfat. Cilj ovog rada bio je da se ispita kvantitet i kvalitet novoformiranog koštanog tkiva posle korišćenja autotransplantata kosti i β-trikalcijum fosfata, na modelu kritičnog defekta kalvarije kunića sa eksperimentalno izazvanim dijabetesom melitusom tipa I. Metode. U ovo istraživanje bilo je uključeno 8 kunića (soj Činičila), starosti 4 meseca, kod kojih je dijabetes melitus tipa I bio izazvan aloksanom. Kod svih životinja hirurški je urađen defekt kritičneveličine na kosti kalvarije (prečnika 12 mm), koji je popunjen autotransplantatom kosti i β-trikalcijum fosfatom (n = 4) ili je ostavljen da spontano zarasta kao kontrolni defekt (n = 4). Posle 4 nedelje, sve životinje su bile žrtvovane i koštani uzorci uzeti za histološku i histomorfometrijsku analizu. Pored deskriptivne histološke analize, urađena je i kvantitativna analiza novoformirane kosti, vezivnog tkiva i materijala za koštanu regeneraciju. Statistička analiza vršena je primenom Friedmanovog testa i post hock Vilkoksonovog neparametrijskog testa sa stepenom značajnosti od p  lt  0,05. Rezultati. Histološka analiza uzoraka kosti pokazala je prisustvo novoformirane kosti na periferiji defekta, dok je u centralom delu bilo prisutno vezivno tkivo, nezrelo koštano tkivo i dobro sjedinjeni neresorbovani materijal za regeneraciju kosti. Kontrolni uzorci nisu pokazali koštano zarastanje defekata. Značajno više novoformirane kosti bilo je prisutno u defektima regenerisanim autotransplantatom (53%) u poređenju sa kontrolnim defektima (7%), (p  lt  0,000) i defektima popunjenim β-trikalcijum fosfatom (30%), (p  lt  0,030). Takođe, značajna razlika uočena je i između grupe sa β-trikalcijum fosfatom i kontrolnim koštanim defektom (p  lt  0,008). Zaključak. Primena autotransplantata kosti značajno povećava uspešnost regeneracije kritičnih defekata kosti kalvarije kunića sa dijabetesom melitusom tipa I.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Histomorphometric evaluation of bone regeneration using autogenous bone and beta-tricalcium phosphate in diabetic rabbits
T1  - Histomorfometrijska analiza regeneracije kosti kod kunića sa dijabetesom melitusom posle primene autotransplantata kosti i beta-trikalcijum fosfata
VL  - 73
IS  - 12
SP  - 1132
EP  - 1138
DO  - 10.2298/VSP151125013Z
ER  - 
@article{
author = "Živadinović, Milka and Andrić, Miroslav and Milošević, Verica and Manojlović-Stojanoski, Milica and Prokić, Branislav and Prokić, Bogomir and Dimić, Aleksandar and Ćalasan, Dejan and Brković, Božidar",
year = "2016",
abstract = "Background/Aim. The mechanism of impaired bone healing in diabetes mellitus includes different tissue and cellular level activities due to micro- and macrovascular changes. As a chronic metabolic disease with vascular complications, diabetes affects a process of bone regeneration as well. The therapeutic approach in bone regeneration is based on the use of osteoinductive autogenous grafts as well as osteoconductive synthetic material, like a β-tricalcium phosphate. The aim of the study was to determine the quality and quantity of new bone formation after the use of autogenous bone and β-tricalcium phosphate in the model of calvarial critical-sized defect in rabbits with induced diabetes mellitus type I. Methods. The study included eight 4-month-old Chincilla rabbits with alloxan-induced diabetes mellitus type I. In all animals, there were surgically created two calvarial bilateral defects (diameter 12 mm), which were grafted with autogenous bone and β-tricalcium phosphate (n = 4) or served as unfilled controls (n = 4). After 4 weeks of healing, animals were sacrificed and calvarial bone blocks were taken for histologic and histomorphometric analysis. Beside descriptive histologic evaluation, the percentage of new bone formation, connective tissue and residual graft were calculated. All parameters were statistically evaluated by Friedman Test and post hock Wilcoxon Singed Ranks Test with a significance of p  lt  0.05. Results. Histology revealed active new bone formation peripherally with centrally located connective tissue, newly formed woven bone and well incorporated residual grafts in all treated defects. Control samples showed no bone bridging of defects. There was a significantly more new bone in autogeonous graft (53%) compared with β-tricalcium phosphate (30%), (p  lt  0.030) and control (7%), (p  lt  0.000) groups. A significant difference was also recorded between β-tricalcium phosphate and control groups (p  lt  0.008). Conclusion. In the present study on the rabbit grafting model with induced diabetes mellitus type I, the effective bone regeneration of critical bone defects was obtained using autogenous bone graft., Uvod/Cilj. Mehanizam otežanog zarastanja tkiva kod dijabetesa melitusa zasnovan je na različitim promenama funkcije na tkivnom i ćelijskom nivou, usled prisutnih mikro- i makrovaskularnih promena. Kao hronično metaboličko oboljenje sa vaskularnim komplikacijama, dijabetes melitus zahvata i proces koštane regeneracije. Terapijski postupci u okviru regeneracije kosti obuhvataju primenu autotransplantata sa oseoinduktivnim delovanjem i sintetskih osteokonduktivnih materijala, kao što je i β-trikalcijum fosfat. Cilj ovog rada bio je da se ispita kvantitet i kvalitet novoformiranog koštanog tkiva posle korišćenja autotransplantata kosti i β-trikalcijum fosfata, na modelu kritičnog defekta kalvarije kunića sa eksperimentalno izazvanim dijabetesom melitusom tipa I. Metode. U ovo istraživanje bilo je uključeno 8 kunića (soj Činičila), starosti 4 meseca, kod kojih je dijabetes melitus tipa I bio izazvan aloksanom. Kod svih životinja hirurški je urađen defekt kritičneveličine na kosti kalvarije (prečnika 12 mm), koji je popunjen autotransplantatom kosti i β-trikalcijum fosfatom (n = 4) ili je ostavljen da spontano zarasta kao kontrolni defekt (n = 4). Posle 4 nedelje, sve životinje su bile žrtvovane i koštani uzorci uzeti za histološku i histomorfometrijsku analizu. Pored deskriptivne histološke analize, urađena je i kvantitativna analiza novoformirane kosti, vezivnog tkiva i materijala za koštanu regeneraciju. Statistička analiza vršena je primenom Friedmanovog testa i post hock Vilkoksonovog neparametrijskog testa sa stepenom značajnosti od p  lt  0,05. Rezultati. Histološka analiza uzoraka kosti pokazala je prisustvo novoformirane kosti na periferiji defekta, dok je u centralom delu bilo prisutno vezivno tkivo, nezrelo koštano tkivo i dobro sjedinjeni neresorbovani materijal za regeneraciju kosti. Kontrolni uzorci nisu pokazali koštano zarastanje defekata. Značajno više novoformirane kosti bilo je prisutno u defektima regenerisanim autotransplantatom (53%) u poređenju sa kontrolnim defektima (7%), (p  lt  0,000) i defektima popunjenim β-trikalcijum fosfatom (30%), (p  lt  0,030). Takođe, značajna razlika uočena je i između grupe sa β-trikalcijum fosfatom i kontrolnim koštanim defektom (p  lt  0,008). Zaključak. Primena autotransplantata kosti značajno povećava uspešnost regeneracije kritičnih defekata kosti kalvarije kunića sa dijabetesom melitusom tipa I.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Histomorphometric evaluation of bone regeneration using autogenous bone and beta-tricalcium phosphate in diabetic rabbits, Histomorfometrijska analiza regeneracije kosti kod kunića sa dijabetesom melitusom posle primene autotransplantata kosti i beta-trikalcijum fosfata",
volume = "73",
number = "12",
pages = "1132-1138",
doi = "10.2298/VSP151125013Z"
}
Živadinović, M., Andrić, M., Milošević, V., Manojlović-Stojanoski, M., Prokić, B., Prokić, B., Dimić, A., Ćalasan, D.,& Brković, B.. (2016). Histomorphometric evaluation of bone regeneration using autogenous bone and beta-tricalcium phosphate in diabetic rabbits. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 73(12), 1132-1138.
https://doi.org/10.2298/VSP151125013Z
Živadinović M, Andrić M, Milošević V, Manojlović-Stojanoski M, Prokić B, Prokić B, Dimić A, Ćalasan D, Brković B. Histomorphometric evaluation of bone regeneration using autogenous bone and beta-tricalcium phosphate in diabetic rabbits. in Vojnosanitetski pregled. 2016;73(12):1132-1138.
doi:10.2298/VSP151125013Z .
Živadinović, Milka, Andrić, Miroslav, Milošević, Verica, Manojlović-Stojanoski, Milica, Prokić, Branislav, Prokić, Bogomir, Dimić, Aleksandar, Ćalasan, Dejan, Brković, Božidar, "Histomorphometric evaluation of bone regeneration using autogenous bone and beta-tricalcium phosphate in diabetic rabbits" in Vojnosanitetski pregled, 73, no. 12 (2016):1132-1138,
https://doi.org/10.2298/VSP151125013Z . .
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4
6

Effect of surgical technique and implant micro and macro design on stability of implants placed in posterior maxilla

Ćalasan, Dejan

(Univerzitet u Beogradu, Stomatološki fakultet, 2014)

TY  - THES
AU  - Ćalasan, Dejan
PY  - 2014
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=2811
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:11004/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=47616271
UR  - http://nardus.mpn.gov.rs/123456789/5206
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/978
AB  - Sufficient primary implant stability is very important factor that affects long-term implant success and depends on diameter and length of the implant, shape of implant body, features of implant threads (macro design), surgical technique used as well as on the quality and quantity of the available jaw bone. Primary stability is hard to achieve in posterior maxilla due to low density of bone in this region. Since the quality and quantity of the jaw bone are factors that are already present, the effect of surgical techniques, implant's macro and micro designs on improvement of implant stability in low-density bone were assessed in this doctoral dissertation. The aim was to investigate and compare implant stability between self-tapping and non self-tapping implants inserted in low-density bone following lateral bone condensing or standard surgical techniques. Also, to investigate and compare implant stability between implants with hydrophobic and hydrophilic surfaces inserted into the low-density bone. Experimental and clinical study were performed. In the „in vitro“ study, pig ribs with uniform thickness of corticalis of 2 mm were used to simulate jaw bone type D3 or D4 according to Carl and Misch classification. With regards to surgical technique (lateral bone condensing or standard surgical technique) and implant macro design (self-tapping and non self-tapping), bone samples were randomly divided into 4 test groups to allow investigation of all possible combinations of the tested factors. Implant stability was measured in thermostat controlled water bath using Resonance Frequency Analysis (RFA) as a method of measurement. A total of 46 patients (26 females and 20 males) with a mean age of 39.3 years were included in the clinical study and they received a total of 144 implants in the following way: 48 self-tapping implants (24 following lateral bone condensation and 24 following standard surgical technique), 48 non self-tapping implants (24 following lateral bone condensation and 24 following standard surgical technique), 24 implants with hydrophilic surface and 24 implants with hydrophobic surface following standard surgical technique...
AB  - Odgovarajuća primarna stabilnost implantata je osovni faktor koji utiče na dugotrajan uspeh endoosealnih implantata, što zavisi od dijametra i dužine implantata, oblika tela implantata, karakteristika navoja implantata (makro dizajn), primenjene hirurške tehnike, kao i od kvaliteta i količine raspoložive kosti. Primarnu stabilnost implantata je teško postići u bočnim segmentima gornje vilice zbog male gustine kosti u ovoj regiji. Kako su kvalitet i količina kosti faktori koji su već prisutni, u ovoj doktorskoj disertaciji ispitivan je uticaj različitih hirurških tehnika, makro i mikro dizajna implantata na poboljšanje stabilnosti implantata u kosti male gustine. Cilj doktorske disertacije je bio ispitati i uporediti vrednosti implantne stabilnosti između implantata sa samourezujućim i neurezujućim navojima ugrađenih nakon preparacije ležišta metodom lateralne kondenzacije i standardnom tehnikom u kost male gustine. Takođe, ispitati i uporediti vrednosti implantne stabilnosti između implantata sa hidrofobnom i implantata sa hidrofilnom površinom ugrađenih u kost male gustine. Preduzeta su eksperimentalna i klinička istraživanja. U sprovedenoj „in vitro“ studiji korišćena su svinjska rebra uniforme debljine koritkalnog sloja od 2 mm radi simulacije klase D3 i D4 po Carl-u i Misch-u humane vilične kosti. Prema hirurškoj tehnici za peparaciju ležišta implantata (lateralna kondenzacija kosti i standardna tehnika) i makro dizajnu implantata (samourezujući i neurezujući), uzorci kosti su metodom slučajnog izbora bili podeljeni u 4 grupe čime je bilo omogućeno ispitivanje svih kombinacija testiranih faktora. Merenje implantatne stabilnosti vršeno je u termostatom kontrolisanom vodenom kupatilu metodom analize rezonantne frekvencije (engl. Resonance Frequency Analysis RFA). U kliničku studiju je bilo uključeno ukupno 46 pacijenata (26 ženskog i 20 muškog pola) prosečne starosti 39.3 godina i kod njih je ugrađeno ukupno 144 implantata i to: 48 samourezujućih implantata (24 u ležišta preparirana lateralnom kondenzacijom kosti i 24 u ležišta preparirana standardnom tehnikom), 48 neurezujućih implantata (24 u ležišta preparirana lateralnom kondenzacijom kosti i 24 u ležišta preparirana standardnom tehnikom), 24 implantata hidrofilne i 24 implantata hidrofobne površine u ležišta preparirana standardnom tehnikom...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Effect of surgical technique and implant micro and macro design on stability of implants placed in posterior maxilla
T1  - Uticaj hirurške tehnike ugradnje i mikro i makro dizajna implantata na njihovu stabilnost u bočnom segmentu gornje vilice
UR  - https://hdl.handle.net/21.15107/rcub_nardus_5206
ER  - 
@phdthesis{
author = "Ćalasan, Dejan",
year = "2014",
abstract = "Sufficient primary implant stability is very important factor that affects long-term implant success and depends on diameter and length of the implant, shape of implant body, features of implant threads (macro design), surgical technique used as well as on the quality and quantity of the available jaw bone. Primary stability is hard to achieve in posterior maxilla due to low density of bone in this region. Since the quality and quantity of the jaw bone are factors that are already present, the effect of surgical techniques, implant's macro and micro designs on improvement of implant stability in low-density bone were assessed in this doctoral dissertation. The aim was to investigate and compare implant stability between self-tapping and non self-tapping implants inserted in low-density bone following lateral bone condensing or standard surgical techniques. Also, to investigate and compare implant stability between implants with hydrophobic and hydrophilic surfaces inserted into the low-density bone. Experimental and clinical study were performed. In the „in vitro“ study, pig ribs with uniform thickness of corticalis of 2 mm were used to simulate jaw bone type D3 or D4 according to Carl and Misch classification. With regards to surgical technique (lateral bone condensing or standard surgical technique) and implant macro design (self-tapping and non self-tapping), bone samples were randomly divided into 4 test groups to allow investigation of all possible combinations of the tested factors. Implant stability was measured in thermostat controlled water bath using Resonance Frequency Analysis (RFA) as a method of measurement. A total of 46 patients (26 females and 20 males) with a mean age of 39.3 years were included in the clinical study and they received a total of 144 implants in the following way: 48 self-tapping implants (24 following lateral bone condensation and 24 following standard surgical technique), 48 non self-tapping implants (24 following lateral bone condensation and 24 following standard surgical technique), 24 implants with hydrophilic surface and 24 implants with hydrophobic surface following standard surgical technique..., Odgovarajuća primarna stabilnost implantata je osovni faktor koji utiče na dugotrajan uspeh endoosealnih implantata, što zavisi od dijametra i dužine implantata, oblika tela implantata, karakteristika navoja implantata (makro dizajn), primenjene hirurške tehnike, kao i od kvaliteta i količine raspoložive kosti. Primarnu stabilnost implantata je teško postići u bočnim segmentima gornje vilice zbog male gustine kosti u ovoj regiji. Kako su kvalitet i količina kosti faktori koji su već prisutni, u ovoj doktorskoj disertaciji ispitivan je uticaj različitih hirurških tehnika, makro i mikro dizajna implantata na poboljšanje stabilnosti implantata u kosti male gustine. Cilj doktorske disertacije je bio ispitati i uporediti vrednosti implantne stabilnosti između implantata sa samourezujućim i neurezujućim navojima ugrađenih nakon preparacije ležišta metodom lateralne kondenzacije i standardnom tehnikom u kost male gustine. Takođe, ispitati i uporediti vrednosti implantne stabilnosti između implantata sa hidrofobnom i implantata sa hidrofilnom površinom ugrađenih u kost male gustine. Preduzeta su eksperimentalna i klinička istraživanja. U sprovedenoj „in vitro“ studiji korišćena su svinjska rebra uniforme debljine koritkalnog sloja od 2 mm radi simulacije klase D3 i D4 po Carl-u i Misch-u humane vilične kosti. Prema hirurškoj tehnici za peparaciju ležišta implantata (lateralna kondenzacija kosti i standardna tehnika) i makro dizajnu implantata (samourezujući i neurezujući), uzorci kosti su metodom slučajnog izbora bili podeljeni u 4 grupe čime je bilo omogućeno ispitivanje svih kombinacija testiranih faktora. Merenje implantatne stabilnosti vršeno je u termostatom kontrolisanom vodenom kupatilu metodom analize rezonantne frekvencije (engl. Resonance Frequency Analysis RFA). U kliničku studiju je bilo uključeno ukupno 46 pacijenata (26 ženskog i 20 muškog pola) prosečne starosti 39.3 godina i kod njih je ugrađeno ukupno 144 implantata i to: 48 samourezujućih implantata (24 u ležišta preparirana lateralnom kondenzacijom kosti i 24 u ležišta preparirana standardnom tehnikom), 48 neurezujućih implantata (24 u ležišta preparirana lateralnom kondenzacijom kosti i 24 u ležišta preparirana standardnom tehnikom), 24 implantata hidrofilne i 24 implantata hidrofobne površine u ležišta preparirana standardnom tehnikom...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Effect of surgical technique and implant micro and macro design on stability of implants placed in posterior maxilla, Uticaj hirurške tehnike ugradnje i mikro i makro dizajna implantata na njihovu stabilnost u bočnom segmentu gornje vilice",
url = "https://hdl.handle.net/21.15107/rcub_nardus_5206"
}
Ćalasan, D.. (2014). Effect of surgical technique and implant micro and macro design on stability of implants placed in posterior maxilla. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_5206
Ćalasan D. Effect of surgical technique and implant micro and macro design on stability of implants placed in posterior maxilla. 2014;.
https://hdl.handle.net/21.15107/rcub_nardus_5206 .
Ćalasan, Dejan, "Effect of surgical technique and implant micro and macro design on stability of implants placed in posterior maxilla" (2014),
https://hdl.handle.net/21.15107/rcub_nardus_5206 .

Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study

Marković, Aleksa; Luis Calvo-Guirado, Jose; Lazić, Zoran; Gomez-Moreno, Gerardo; Ćalasan, Dejan; Guardia, Javier; Čolić, Snježana; Aguilar-Salvatierra, Antonio; Gačić, Bojan; Delgado-Ruiz, Rafael; Janjić, Bojan; Mišić, Tijana

(Wiley, Hoboken, 2013)

TY  - JOUR
AU  - Marković, Aleksa
AU  - Luis Calvo-Guirado, Jose
AU  - Lazić, Zoran
AU  - Gomez-Moreno, Gerardo
AU  - Ćalasan, Dejan
AU  - Guardia, Javier
AU  - Čolić, Snježana
AU  - Aguilar-Salvatierra, Antonio
AU  - Gačić, Bojan
AU  - Delgado-Ruiz, Rafael
AU  - Janjić, Bojan
AU  - Mišić, Tijana
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1816
AB  - Purpose: The aim of this study was to investigate the relationship between surgical techniques and implant macro-design (self-tapping/non-self-tapping) for the optimization of implant stability in the low-density bone present in the posterior maxilla using resonance frequency analysis (RFA). Materials and Methods: A total of 102 implants were studied. Fifty-six self-tapping BlueSkyBredent (R) (Bredent GmbH &, Senden, Germany) and 56 non-self-tapping Standard Plus Straumann (R) (Institut Straumann AG (R), Waldenburg, Switzerland) were placed in the posterior segment of the maxilla. Implants of both types were placed in sites prepared with either lateral bone-condensing or with bone-drilling techniques. Implant stability measurements were performed using RFA immediately after implant placement and weekly during a 12-week follow-up period. Results: Both types of implants placed after bone condensing achieved significantly higher stability immediately after surgery, as well as during the entire 12-week observation period compared with those placed following bone drilling. After bone condensation, there were no significant differences in primary stability or in implant stability after the first week between both implant types. From 2 to 12 postoperative weeks, significantly higher stability was shown by self-tapping implants. After bone drilling, self-tapping implants achieved significantly higher stability than non-self-tapping implants during the entire follow-up period. Conclusions: The outcomes of the present study indicate that bone drilling is not an effective technique for improving implant stability and, following this technique, the use of self-tapping implants is highly recommended. Implant stability optimization in the soft bone can be achieved by lateral bone-condensing technique, regardless of implant macro-design.
PB  - Wiley, Hoboken
T2  - Clinical Implant Dentistry & Related Research
T1  - Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study
VL  - 15
IS  - 3
SP  - 341
EP  - 349
DO  - 10.1111/j.1708-8208.2011.00415.x
ER  - 
@article{
author = "Marković, Aleksa and Luis Calvo-Guirado, Jose and Lazić, Zoran and Gomez-Moreno, Gerardo and Ćalasan, Dejan and Guardia, Javier and Čolić, Snježana and Aguilar-Salvatierra, Antonio and Gačić, Bojan and Delgado-Ruiz, Rafael and Janjić, Bojan and Mišić, Tijana",
year = "2013",
abstract = "Purpose: The aim of this study was to investigate the relationship between surgical techniques and implant macro-design (self-tapping/non-self-tapping) for the optimization of implant stability in the low-density bone present in the posterior maxilla using resonance frequency analysis (RFA). Materials and Methods: A total of 102 implants were studied. Fifty-six self-tapping BlueSkyBredent (R) (Bredent GmbH &, Senden, Germany) and 56 non-self-tapping Standard Plus Straumann (R) (Institut Straumann AG (R), Waldenburg, Switzerland) were placed in the posterior segment of the maxilla. Implants of both types were placed in sites prepared with either lateral bone-condensing or with bone-drilling techniques. Implant stability measurements were performed using RFA immediately after implant placement and weekly during a 12-week follow-up period. Results: Both types of implants placed after bone condensing achieved significantly higher stability immediately after surgery, as well as during the entire 12-week observation period compared with those placed following bone drilling. After bone condensation, there were no significant differences in primary stability or in implant stability after the first week between both implant types. From 2 to 12 postoperative weeks, significantly higher stability was shown by self-tapping implants. After bone drilling, self-tapping implants achieved significantly higher stability than non-self-tapping implants during the entire follow-up period. Conclusions: The outcomes of the present study indicate that bone drilling is not an effective technique for improving implant stability and, following this technique, the use of self-tapping implants is highly recommended. Implant stability optimization in the soft bone can be achieved by lateral bone-condensing technique, regardless of implant macro-design.",
publisher = "Wiley, Hoboken",
journal = "Clinical Implant Dentistry & Related Research",
title = "Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study",
volume = "15",
number = "3",
pages = "341-349",
doi = "10.1111/j.1708-8208.2011.00415.x"
}
Marković, A., Luis Calvo-Guirado, J., Lazić, Z., Gomez-Moreno, G., Ćalasan, D., Guardia, J., Čolić, S., Aguilar-Salvatierra, A., Gačić, B., Delgado-Ruiz, R., Janjić, B.,& Mišić, T.. (2013). Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study. in Clinical Implant Dentistry & Related Research
Wiley, Hoboken., 15(3), 341-349.
https://doi.org/10.1111/j.1708-8208.2011.00415.x
Marković A, Luis Calvo-Guirado J, Lazić Z, Gomez-Moreno G, Ćalasan D, Guardia J, Čolić S, Aguilar-Salvatierra A, Gačić B, Delgado-Ruiz R, Janjić B, Mišić T. Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study. in Clinical Implant Dentistry & Related Research. 2013;15(3):341-349.
doi:10.1111/j.1708-8208.2011.00415.x .
Marković, Aleksa, Luis Calvo-Guirado, Jose, Lazić, Zoran, Gomez-Moreno, Gerardo, Ćalasan, Dejan, Guardia, Javier, Čolić, Snježana, Aguilar-Salvatierra, Antonio, Gačić, Bojan, Delgado-Ruiz, Rafael, Janjić, Bojan, Mišić, Tijana, "Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study" in Clinical Implant Dentistry & Related Research, 15, no. 3 (2013):341-349,
https://doi.org/10.1111/j.1708-8208.2011.00415.x . .
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44
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Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study

Marković, Aleksa; Ćalasan, Dejan; Čolić, Snježana; Stojčev-Stajčić, Ljiljana; Janjić, Bojan; Mišić, Tijana

(Mosby-Elsevier, New York, 2011)

TY  - JOUR
AU  - Marković, Aleksa
AU  - Ćalasan, Dejan
AU  - Čolić, Snježana
AU  - Stojčev-Stajčić, Ljiljana
AU  - Janjić, Bojan
AU  - Mišić, Tijana
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1612
AB  - Objective. The aim of this clinical trial was to compare primary and secondary stability of implants placed by bone condensing versus the standard drilling technique in the posterior edentulous maxilla. Study design. Forty-eight SLA Straumann implants 4.1 x 10 mm (Institut Straumann AG, Waldenburg, Switzerland) were placed into edentulous maxillary posterior region in the same positions bilaterally, using the bone condensation technique for one and the standard technique for the other side. Implant stability measurements were performed immediately after implant placement, as well as every week for the next 6 weeks by use of resonance frequency analysis (RFA). Data were analyzed using Mann-Whitney U and Wilcoxon tests. Results. After bone condensing, significantly higher implant stability was recorded immediately after surgery as well as during the whole observation period of 6 weeks compared with bone-drilling technique (Mann-Whitney U test, P  lt  .000). Conclusions. The bone-condensing technique can be recommended as an alternate surgical approach for implant site preparation in reduced bone density to achieve greater implant stability in the posterior maxilla. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 557-563)
PB  - Mosby-Elsevier, New York
T2  - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
T1  - Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study
VL  - 112
IS  - 5
SP  - 557
EP  - 563
DO  - 10.1016/j.tripleo.2010.11.010
ER  - 
@article{
author = "Marković, Aleksa and Ćalasan, Dejan and Čolić, Snježana and Stojčev-Stajčić, Ljiljana and Janjić, Bojan and Mišić, Tijana",
year = "2011",
abstract = "Objective. The aim of this clinical trial was to compare primary and secondary stability of implants placed by bone condensing versus the standard drilling technique in the posterior edentulous maxilla. Study design. Forty-eight SLA Straumann implants 4.1 x 10 mm (Institut Straumann AG, Waldenburg, Switzerland) were placed into edentulous maxillary posterior region in the same positions bilaterally, using the bone condensation technique for one and the standard technique for the other side. Implant stability measurements were performed immediately after implant placement, as well as every week for the next 6 weeks by use of resonance frequency analysis (RFA). Data were analyzed using Mann-Whitney U and Wilcoxon tests. Results. After bone condensing, significantly higher implant stability was recorded immediately after surgery as well as during the whole observation period of 6 weeks compared with bone-drilling technique (Mann-Whitney U test, P  lt  .000). Conclusions. The bone-condensing technique can be recommended as an alternate surgical approach for implant site preparation in reduced bone density to achieve greater implant stability in the posterior maxilla. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 557-563)",
publisher = "Mosby-Elsevier, New York",
journal = "Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology",
title = "Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study",
volume = "112",
number = "5",
pages = "557-563",
doi = "10.1016/j.tripleo.2010.11.010"
}
Marković, A., Ćalasan, D., Čolić, S., Stojčev-Stajčić, L., Janjić, B.,& Mišić, T.. (2011). Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
Mosby-Elsevier, New York., 112(5), 557-563.
https://doi.org/10.1016/j.tripleo.2010.11.010
Marković A, Ćalasan D, Čolić S, Stojčev-Stajčić L, Janjić B, Mišić T. Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology. 2011;112(5):557-563.
doi:10.1016/j.tripleo.2010.11.010 .
Marković, Aleksa, Ćalasan, Dejan, Čolić, Snježana, Stojčev-Stajčić, Ljiljana, Janjić, Bojan, Mišić, Tijana, "Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study" in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology, 112, no. 5 (2011):557-563,
https://doi.org/10.1016/j.tripleo.2010.11.010 . .
3
38
31
38

Radiološka procena gustine kosti nakon ugradnje endoosealnih implantata

Ćalasan, Dejan

(Univerzitet u Beogradu, Stomatološki fakultet, 2007)

TY  - THES
AU  - Ćalasan, Dejan
PY  - 2007
UR  - https://plus.sr.cobiss.net/opac7/bib/1024056974
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/435
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Radiološka procena gustine kosti nakon ugradnje endoosealnih implantata
UR  - https://hdl.handle.net/21.15107/rcub_smile_435
ER  - 
@mastersthesis{
author = "Ćalasan, Dejan",
year = "2007",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Radiološka procena gustine kosti nakon ugradnje endoosealnih implantata",
url = "https://hdl.handle.net/21.15107/rcub_smile_435"
}
Ćalasan, D.. (2007). Radiološka procena gustine kosti nakon ugradnje endoosealnih implantata. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_435
Ćalasan D. Radiološka procena gustine kosti nakon ugradnje endoosealnih implantata. 2007;.
https://hdl.handle.net/21.15107/rcub_smile_435 .
Ćalasan, Dejan, "Radiološka procena gustine kosti nakon ugradnje endoosealnih implantata" (2007),
https://hdl.handle.net/21.15107/rcub_smile_435 .