TY  - JOUR
AU  - Marković, Dejan
AU  - Karadžić, Ivana
AU  - Jokanović, Vukoman
AU  - Vuković, Ana
AU  - Vučić, Vesna
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2083
AB  - Millions of patients worldwide need surgery to repair or replace tissue that has been damaged through trauma or disease. To solve the problem of lost tissue, a major emphasis of tissue engineering (TE) is on tissue regeneration. Stem cells and highly porous biomaterials used as cell carriers (scaffolds) have an essential role in the production of new tissue by TE. The cellular component is important for the generation and establishment of the extracellular matrix, while a scaffold is necessary to determine the shape of the newly formed tissue and facilitate migration of cells into the desired location, as well as their growth and differentiation. This review describes the types, characteristics and classification of stem cells. Furthermore, it includes functional features of cell carriers - biocompatibility, biodegradability and mechanical properties of biomaterials used in developing state-of-the-an scaffolds for TE applications, as well as suitability for different tissues. Moreover, it explains the importance of nanotechnology and defines the challenges and the purpose of future research in this rapidly advancing field.
PB  - Savez hemijskih inženjera, Beograd
T2  - Chemical Industry & Chemical Engineering Quarterly / CICEQ
T1  - Biological aspects of application of nanomaterials in tissue engineering
VL  - 22
IS  - 2
SP  - 145
EP  - 153
DO  - 10.2298/CICEQ141231028M
ER  - 

@article{
author = "Marković, Dejan and Karadžić, Ivana and Jokanović, Vukoman and Vuković, Ana and Vučić, Vesna",
year = "2016",
abstract = "Millions of patients worldwide need surgery to repair or replace tissue that has been damaged through trauma or disease. To solve the problem of lost tissue, a major emphasis of tissue engineering (TE) is on tissue regeneration. Stem cells and highly porous biomaterials used as cell carriers (scaffolds) have an essential role in the production of new tissue by TE. The cellular component is important for the generation and establishment of the extracellular matrix, while a scaffold is necessary to determine the shape of the newly formed tissue and facilitate migration of cells into the desired location, as well as their growth and differentiation. This review describes the types, characteristics and classification of stem cells. Furthermore, it includes functional features of cell carriers - biocompatibility, biodegradability and mechanical properties of biomaterials used in developing state-of-the-an scaffolds for TE applications, as well as suitability for different tissues. Moreover, it explains the importance of nanotechnology and defines the challenges and the purpose of future research in this rapidly advancing field.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Chemical Industry & Chemical Engineering Quarterly / CICEQ",
title = "Biological aspects of application of nanomaterials in tissue engineering",
volume = "22",
number = "2",
pages = "145-153",
doi = "10.2298/CICEQ141231028M"
}

Marković, D., Karadžić, I., Jokanović, V., Vuković, A.,& Vučić, V.. (2016). Biological aspects of application of nanomaterials in tissue engineering. in Chemical Industry & Chemical Engineering Quarterly / CICEQ
Savez hemijskih inženjera, Beograd., 22(2), 145-153.
https://doi.org/10.2298/CICEQ141231028M

Marković D, Karadžić I, Jokanović V, Vuković A, Vučić V. Biological aspects of application of nanomaterials in tissue engineering. in Chemical Industry & Chemical Engineering Quarterly / CICEQ. 2016;22(2):145-153.
doi:10.2298/CICEQ141231028M .

Marković, Dejan, Karadžić, Ivana, Jokanović, Vukoman, Vuković, Ana, Vučić, Vesna, "Biological aspects of application of nanomaterials in tissue engineering" in Chemical Industry & Chemical Engineering Quarterly / CICEQ, 22, no. 2 (2016):145-153,
https://doi.org/10.2298/CICEQ141231028M . .

TY  - JOUR
AU  - Karadžić, Ivana
AU  - Vučić, Vesna
AU  - Jokanović, Vukoman
AU  - Debeljak-Martačić, Jasmina
AU  - Marković, Dejan
AU  - Petrović, Snježana
AU  - Glibetić, Marija
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2063
AB  - The aim of this study was to examine the differential capacity of isolated dental pulp stem cells (SHED) cultured onto four different scaffold materials. The differential potential of isolated SHED was examined on the following scaffolds: porous hydroxyapatite (pHAP) alone or combined with three polymers [polylactic-co-glycolic acid (PLGA), alginate, and ethylene vinylacetate / ethylene vinylversatate (EVA/EVV)]. SHED were isolated by outgrowth method and characterized by the flow cytometry. Viability of cells grown with scaffolds was assessed by MTT and LDH assays. No significant cytotoxic effect of any of the tested materials was shown. Staining with alizarin red and estimated alkaline phosphatase activity to identify differentiation, demonstrated osteoblastic phenotype of SHED and newly deposited and mineralized extra cellular matrix (ECM) in presence of all tested scaffolds. The developed ECM seen at scanning electronic micrographs additionally confirmed the osteogenic differentiation and biocompatibility between cells and materials. In summary, all studied biomaterials are suitable carriers for proliferation and osteoblastic differentiation of dental pulp mesenchymal stem cells in vitro.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Biomedical Materials Research Part A
T1  - Effects of novel hydroxyapatite-based 3D biomaterials on proliferation and osteoblastic differentiation of mesenchymal stem cells
VL  - 103
IS  - 1
SP  - 350
EP  - 357
DO  - 10.1002/jbm.a.35180
ER  - 

@article{
author = "Karadžić, Ivana and Vučić, Vesna and Jokanović, Vukoman and Debeljak-Martačić, Jasmina and Marković, Dejan and Petrović, Snježana and Glibetić, Marija",
year = "2015",
abstract = "The aim of this study was to examine the differential capacity of isolated dental pulp stem cells (SHED) cultured onto four different scaffold materials. The differential potential of isolated SHED was examined on the following scaffolds: porous hydroxyapatite (pHAP) alone or combined with three polymers [polylactic-co-glycolic acid (PLGA), alginate, and ethylene vinylacetate / ethylene vinylversatate (EVA/EVV)]. SHED were isolated by outgrowth method and characterized by the flow cytometry. Viability of cells grown with scaffolds was assessed by MTT and LDH assays. No significant cytotoxic effect of any of the tested materials was shown. Staining with alizarin red and estimated alkaline phosphatase activity to identify differentiation, demonstrated osteoblastic phenotype of SHED and newly deposited and mineralized extra cellular matrix (ECM) in presence of all tested scaffolds. The developed ECM seen at scanning electronic micrographs additionally confirmed the osteogenic differentiation and biocompatibility between cells and materials. In summary, all studied biomaterials are suitable carriers for proliferation and osteoblastic differentiation of dental pulp mesenchymal stem cells in vitro.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Biomedical Materials Research Part A",
title = "Effects of novel hydroxyapatite-based 3D biomaterials on proliferation and osteoblastic differentiation of mesenchymal stem cells",
volume = "103",
number = "1",
pages = "350-357",
doi = "10.1002/jbm.a.35180"
}

Karadžić, I., Vučić, V., Jokanović, V., Debeljak-Martačić, J., Marković, D., Petrović, S.,& Glibetić, M.. (2015). Effects of novel hydroxyapatite-based 3D biomaterials on proliferation and osteoblastic differentiation of mesenchymal stem cells. in Journal of Biomedical Materials Research Part A
Wiley-Blackwell, Hoboken., 103(1), 350-357.
https://doi.org/10.1002/jbm.a.35180

Karadžić I, Vučić V, Jokanović V, Debeljak-Martačić J, Marković D, Petrović S, Glibetić M. Effects of novel hydroxyapatite-based 3D biomaterials on proliferation and osteoblastic differentiation of mesenchymal stem cells. in Journal of Biomedical Materials Research Part A. 2015;103(1):350-357.
doi:10.1002/jbm.a.35180 .

Karadžić, Ivana, Vučić, Vesna, Jokanović, Vukoman, Debeljak-Martačić, Jasmina, Marković, Dejan, Petrović, Snježana, Glibetić, Marija, "Effects of novel hydroxyapatite-based 3D biomaterials on proliferation and osteoblastic differentiation of mesenchymal stem cells" in Journal of Biomedical Materials Research Part A, 103, no. 1 (2015):350-357,
https://doi.org/10.1002/jbm.a.35180 . .

TY  - JOUR
AU  - Marković, Dejan
AU  - Ristić-Medić, Danijela
AU  - Vučić, Vesna
AU  - Mitrović, Goran
AU  - Nikolić-Ivošević, Jelena
AU  - Perić, Tamara
AU  - Karadžić, Ivana
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2015
AB  - BackgroundChildhood obesity, dental caries, and periodontal disease are major public health problems due to their adverse impact on the growth and development of children. AimTo examine the association between nutritional status, oral health, and lifestyle habits among schoolchildren in Serbia. DesignThis cross-sectional study assessed 422 children and adolescents aged 6-18years with the following dental indexes analyzed: DMF/dmf (decayed, missed, and filled teeth), plaque index (PI), and gingival index (GI). Depending on their nutritional status, the subjects were categorized, as being normal weight,' at risk of overweight,' and overweight.' Logistic regression was applied to study the association between the dental indexes and independent variables: gender, age, toothbrushing, nutritional status, and lifestyle factors. ResultsBeing overweight positively correlated with GI, but negatively correlated with the DMF/dmf index among the participants. Multivariate analysis showed a strong association between the weight category and toothbrushing with GI and PI. Overweight children (6-11years) were less likely to have caries, whereas in older children/adolescents (12-18years), caries was associated with the intake of sugar-sweetened juices. ConclusionsBeing overweight was found to be significantly associated with a higher probability of developing gingivitis and negatively associated with caries prevalence in Serbian children and adolescents.
PB  - Wiley, Hoboken
T2  - International Journal of Paediatric Dentistry
T1  - Association between being overweight and oral health in Serbian schoolchildren
VL  - 25
IS  - 6
SP  - 409
EP  - 417
DO  - 10.1111/ipd.12147
ER  - 

@article{
author = "Marković, Dejan and Ristić-Medić, Danijela and Vučić, Vesna and Mitrović, Goran and Nikolić-Ivošević, Jelena and Perić, Tamara and Karadžić, Ivana",
year = "2015",
abstract = "BackgroundChildhood obesity, dental caries, and periodontal disease are major public health problems due to their adverse impact on the growth and development of children. AimTo examine the association between nutritional status, oral health, and lifestyle habits among schoolchildren in Serbia. DesignThis cross-sectional study assessed 422 children and adolescents aged 6-18years with the following dental indexes analyzed: DMF/dmf (decayed, missed, and filled teeth), plaque index (PI), and gingival index (GI). Depending on their nutritional status, the subjects were categorized, as being normal weight,' at risk of overweight,' and overweight.' Logistic regression was applied to study the association between the dental indexes and independent variables: gender, age, toothbrushing, nutritional status, and lifestyle factors. ResultsBeing overweight positively correlated with GI, but negatively correlated with the DMF/dmf index among the participants. Multivariate analysis showed a strong association between the weight category and toothbrushing with GI and PI. Overweight children (6-11years) were less likely to have caries, whereas in older children/adolescents (12-18years), caries was associated with the intake of sugar-sweetened juices. ConclusionsBeing overweight was found to be significantly associated with a higher probability of developing gingivitis and negatively associated with caries prevalence in Serbian children and adolescents.",
publisher = "Wiley, Hoboken",
journal = "International Journal of Paediatric Dentistry",
title = "Association between being overweight and oral health in Serbian schoolchildren",
volume = "25",
number = "6",
pages = "409-417",
doi = "10.1111/ipd.12147"
}

Marković, D., Ristić-Medić, D., Vučić, V., Mitrović, G., Nikolić-Ivošević, J., Perić, T.,& Karadžić, I.. (2015). Association between being overweight and oral health in Serbian schoolchildren. in International Journal of Paediatric Dentistry
Wiley, Hoboken., 25(6), 409-417.
https://doi.org/10.1111/ipd.12147

Marković D, Ristić-Medić D, Vučić V, Mitrović G, Nikolić-Ivošević J, Perić T, Karadžić I. Association between being overweight and oral health in Serbian schoolchildren. in International Journal of Paediatric Dentistry. 2015;25(6):409-417.
doi:10.1111/ipd.12147 .

Marković, Dejan, Ristić-Medić, Danijela, Vučić, Vesna, Mitrović, Goran, Nikolić-Ivošević, Jelena, Perić, Tamara, Karadžić, Ivana, "Association between being overweight and oral health in Serbian schoolchildren" in International Journal of Paediatric Dentistry, 25, no. 6 (2015):409-417,
https://doi.org/10.1111/ipd.12147 . .