TY  - JOUR
AU  - Dožić, Marko
AU  - Stojanović-Rundić, Suzana
AU  - Plešinac-Karapandžić, Vesna
AU  - Milošević, Nikola
AU  - Jovanović, Svetlana
AU  - Anđelski-Radičević, Biljana
AU  - Dožić, Ivan
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2177
AB  - Colorectal cancer is the most frequent gastrointestinal tumor, very often situated in the rectum. Serbia is for long period of time in group of European countries with average incidence and high mortality of rectal cancer. Aim: To investigate if histopathological type and grade of cancer and time before local recurrence depend on patients' sex, considering that rectal cancer is more often present in male than in female. Material and methods: A retrospective study (2004‒2013.) included 49 patients from Institute for oncology and radiology in Belgrade, with locally recurrent rectal cancer (29 male and 20 female). All the patients with primary rectal cancer had surgical treatment; postoperative adjuvant chemotherapy was applied in 25 patients. Results: Mean age of our patients is 68 years (min 32, max 84 years). Recurrent rectal cancer is most frequent in group 70‒79 years, both in men and women. Adenocarcinoma is histopathological type of rectal cancer in 96% of patients. The most frequent HP grade is moderately differentiated tumor, grade II (p lt 0,0001). Local recurrences appear within two years after surgery (p=0,0109). Conclusion: We didn't establish correlation between histopathological type and grade of rectal cancer and period of local recurrence related to patients' sex. Given the prevalence of both sexes, screening of patients, adequate diagnosis and timely treatment are most important.
AB  - Karcinomi debelog creva su najčešći tumori digestivnog trakta sa veoma čestom lokalizacijom u rektumu. Naša zemlja se već duži niz godina nalazi u grupi evropskih zemalja sa srednje visokim stopama obolevanja i visokim stopama smrtnosti od ovog karcinoma. Cilj: Utvrditi da li histopatološki tip i gradus karcinoma i vreme do pojave recidiva zavise od pola pacijenta, s obzirom na to da je karcinom rektuma češće prisutan kod muškaraca nego kod žena. Materijal i metode: U retrospektivnu studiju koja obuhvata period od 2004. do 2013. godine uključeno je 49 pacijenata Instituta za onkologiju i radiologiju u Beogradu sa recidivima karcinoma rektuma (29 muškaraca i 20 žena). Svi bolesnici sa primarnim karcinomom rektuma bili su operisani, a postoperativno je sprovedena adjuvantna hemioterapija kod 25 pacijenata. Rezultati: Prosečna starost naših ispitanika bila je 68 godina (najmlađi pacijent imao je 32 godine, a najstariji 84). Najveća učestalost recidiva karcinoma rektuma je u starosnoj grupi 70‒79 godina kod oba pola. Kod 96% pacijenata histopatološki tip tumora je adenokarcinom. Najčešći histopatološki gradus tumora u ispitanoj grupi je srednje diferentovani tumor, gradus II (p lt 0,0001). Recidivi su se uglavnom javljali u prve dve godine nakon operacije (p=0,0109). Zaključak: Nije utvrđena statistički značajna razlika između histopatološkog tipa i gradusa karcinoma rektuma i vremena od operacije do pojave recidiva u odnosu na pol pacijenata. S obzirom na rasprostranjenost bolesti kod oba pola zaključujemo da je radi pravovremenog lečenja najvažniji skrining pacijenata i adekvatna dijagnostika.
PB  - Komora zdravstvenih ustanova Srbije, Beograd
T2  - Zdravstvena zaštita
T1  - Recurrent rectal cancer related to patients sex
T1  - Pojava recidiva karcinoma rektuma u odnosu na pol ispitanika
VL  - 45
IS  - 3
SP  - 13
EP  - 19
DO  - 10.5937/ZZ1603013D
ER  - 

@article{
author = "Dožić, Marko and Stojanović-Rundić, Suzana and Plešinac-Karapandžić, Vesna and Milošević, Nikola and Jovanović, Svetlana and Anđelski-Radičević, Biljana and Dožić, Ivan",
year = "2016",
abstract = "Colorectal cancer is the most frequent gastrointestinal tumor, very often situated in the rectum. Serbia is for long period of time in group of European countries with average incidence and high mortality of rectal cancer. Aim: To investigate if histopathological type and grade of cancer and time before local recurrence depend on patients' sex, considering that rectal cancer is more often present in male than in female. Material and methods: A retrospective study (2004‒2013.) included 49 patients from Institute for oncology and radiology in Belgrade, with locally recurrent rectal cancer (29 male and 20 female). All the patients with primary rectal cancer had surgical treatment; postoperative adjuvant chemotherapy was applied in 25 patients. Results: Mean age of our patients is 68 years (min 32, max 84 years). Recurrent rectal cancer is most frequent in group 70‒79 years, both in men and women. Adenocarcinoma is histopathological type of rectal cancer in 96% of patients. The most frequent HP grade is moderately differentiated tumor, grade II (p lt 0,0001). Local recurrences appear within two years after surgery (p=0,0109). Conclusion: We didn't establish correlation between histopathological type and grade of rectal cancer and period of local recurrence related to patients' sex. Given the prevalence of both sexes, screening of patients, adequate diagnosis and timely treatment are most important., Karcinomi debelog creva su najčešći tumori digestivnog trakta sa veoma čestom lokalizacijom u rektumu. Naša zemlja se već duži niz godina nalazi u grupi evropskih zemalja sa srednje visokim stopama obolevanja i visokim stopama smrtnosti od ovog karcinoma. Cilj: Utvrditi da li histopatološki tip i gradus karcinoma i vreme do pojave recidiva zavise od pola pacijenta, s obzirom na to da je karcinom rektuma češće prisutan kod muškaraca nego kod žena. Materijal i metode: U retrospektivnu studiju koja obuhvata period od 2004. do 2013. godine uključeno je 49 pacijenata Instituta za onkologiju i radiologiju u Beogradu sa recidivima karcinoma rektuma (29 muškaraca i 20 žena). Svi bolesnici sa primarnim karcinomom rektuma bili su operisani, a postoperativno je sprovedena adjuvantna hemioterapija kod 25 pacijenata. Rezultati: Prosečna starost naših ispitanika bila je 68 godina (najmlađi pacijent imao je 32 godine, a najstariji 84). Najveća učestalost recidiva karcinoma rektuma je u starosnoj grupi 70‒79 godina kod oba pola. Kod 96% pacijenata histopatološki tip tumora je adenokarcinom. Najčešći histopatološki gradus tumora u ispitanoj grupi je srednje diferentovani tumor, gradus II (p lt 0,0001). Recidivi su se uglavnom javljali u prve dve godine nakon operacije (p=0,0109). Zaključak: Nije utvrđena statistički značajna razlika između histopatološkog tipa i gradusa karcinoma rektuma i vremena od operacije do pojave recidiva u odnosu na pol pacijenata. S obzirom na rasprostranjenost bolesti kod oba pola zaključujemo da je radi pravovremenog lečenja najvažniji skrining pacijenata i adekvatna dijagnostika.",
publisher = "Komora zdravstvenih ustanova Srbije, Beograd",
journal = "Zdravstvena zaštita",
title = "Recurrent rectal cancer related to patients sex, Pojava recidiva karcinoma rektuma u odnosu na pol ispitanika",
volume = "45",
number = "3",
pages = "13-19",
doi = "10.5937/ZZ1603013D"
}

Dožić, M., Stojanović-Rundić, S., Plešinac-Karapandžić, V., Milošević, N., Jovanović, S., Anđelski-Radičević, B.,& Dožić, I.. (2016). Recurrent rectal cancer related to patients sex. in Zdravstvena zaštita
Komora zdravstvenih ustanova Srbije, Beograd., 45(3), 13-19.
https://doi.org/10.5937/ZZ1603013D

Dožić M, Stojanović-Rundić S, Plešinac-Karapandžić V, Milošević N, Jovanović S, Anđelski-Radičević B, Dožić I. Recurrent rectal cancer related to patients sex. in Zdravstvena zaštita. 2016;45(3):13-19.
doi:10.5937/ZZ1603013D .

Dožić, Marko, Stojanović-Rundić, Suzana, Plešinac-Karapandžić, Vesna, Milošević, Nikola, Jovanović, Svetlana, Anđelski-Radičević, Biljana, Dožić, Ivan, "Recurrent rectal cancer related to patients sex" in Zdravstvena zaštita, 45, no. 3 (2016):13-19,
https://doi.org/10.5937/ZZ1603013D . .

TY  - JOUR
AU  - Dožić, Branko
AU  - Cvetković, Dubravka
AU  - Dožić, Marko
AU  - Bumbaširević, Ljiljana
PY  - 2003
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1182
AB  - A 51-year-old female patient was admitted to the Neurological clinic because of motor seizures with myoclonus of the right hand and right side of the face. The results of initial brain CT scan, chest X rays, EEG ultrasonography of the great blood vessels and laboratory tests made in another hospital were unremarkable. Because of repeated partial seizures transient aphasic disturbances, urinary sphincter disturbances and periodic low-grade fever the patient was transferred to our hospital four months after the disease onset. Laboratory tests and NMR suggested a nonspecific disseminated viral encephalitis. After administration of Endoxan she was ambulatory for several weeks and then became increasingly exhausted confused, febrile, dyspneic, tachypneic and developed a shock status with hepatorenal insufficiency. She died after 7 months of disease duration. Postmortem examination revealed intravascular collections of large atypical lymphoid cells of B cell line. Blood vessels changed in this way were common in the brain and rare in other organs including skin, lungs, heart, liver spleen and digestive system. They were not found in the lymph nodes and bone marrow. A biopsy was not done because of absence of symptomatic and swollen tissues. However, correlation of clinical feature and postmortem findings shows that absence of clinical manifestations in an organ does not mean lack of microscopic pathological changes and biopsy should be done regardless of absence of clinical signs. This case shows that intravascular lymphoma may mimic vasculitis or disseminated nonspecific viral encephalitis.
PB  - Institut za onkologiju, Sremska Kamenica
T2  - Archive of Oncology
T1  - Intravascular large cell lymphoma: Clinicopathological and immunohistochemical description of a case
VL  - 11
IS  - 1
SP  - 21
EP  - 24
DO  - 10.2298/AOO0301021D
ER  - 

@article{
author = "Dožić, Branko and Cvetković, Dubravka and Dožić, Marko and Bumbaširević, Ljiljana",
year = "2003",
abstract = "A 51-year-old female patient was admitted to the Neurological clinic because of motor seizures with myoclonus of the right hand and right side of the face. The results of initial brain CT scan, chest X rays, EEG ultrasonography of the great blood vessels and laboratory tests made in another hospital were unremarkable. Because of repeated partial seizures transient aphasic disturbances, urinary sphincter disturbances and periodic low-grade fever the patient was transferred to our hospital four months after the disease onset. Laboratory tests and NMR suggested a nonspecific disseminated viral encephalitis. After administration of Endoxan she was ambulatory for several weeks and then became increasingly exhausted confused, febrile, dyspneic, tachypneic and developed a shock status with hepatorenal insufficiency. She died after 7 months of disease duration. Postmortem examination revealed intravascular collections of large atypical lymphoid cells of B cell line. Blood vessels changed in this way were common in the brain and rare in other organs including skin, lungs, heart, liver spleen and digestive system. They were not found in the lymph nodes and bone marrow. A biopsy was not done because of absence of symptomatic and swollen tissues. However, correlation of clinical feature and postmortem findings shows that absence of clinical manifestations in an organ does not mean lack of microscopic pathological changes and biopsy should be done regardless of absence of clinical signs. This case shows that intravascular lymphoma may mimic vasculitis or disseminated nonspecific viral encephalitis.",
publisher = "Institut za onkologiju, Sremska Kamenica",
journal = "Archive of Oncology",
title = "Intravascular large cell lymphoma: Clinicopathological and immunohistochemical description of a case",
volume = "11",
number = "1",
pages = "21-24",
doi = "10.2298/AOO0301021D"
}

Dožić, B., Cvetković, D., Dožić, M.,& Bumbaširević, L.. (2003). Intravascular large cell lymphoma: Clinicopathological and immunohistochemical description of a case. in Archive of Oncology
Institut za onkologiju, Sremska Kamenica., 11(1), 21-24.
https://doi.org/10.2298/AOO0301021D

Dožić B, Cvetković D, Dožić M, Bumbaširević L. Intravascular large cell lymphoma: Clinicopathological and immunohistochemical description of a case. in Archive of Oncology. 2003;11(1):21-24.
doi:10.2298/AOO0301021D .

Dožić, Branko, Cvetković, Dubravka, Dožić, Marko, Bumbaširević, Ljiljana, "Intravascular large cell lymphoma: Clinicopathological and immunohistochemical description of a case" in Archive of Oncology, 11, no. 1 (2003):21-24,
https://doi.org/10.2298/AOO0301021D . .