TY  - JOUR
AU  - Sabeti, Mohammad
AU  - Golchert, Kory J.
AU  - Shirgill, Neveed
AU  - Jakovljević, Aleksandar
AU  - Andrić, Miroslav
AU  - Milašin, Jelena
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2583
AB  - There is a need for updating the current treatment modalities for periapical lesions of endodontic origin to reflect the contributions and potential morbidity from herpesvirus infection. Herpesviruses, particularly human cytomegalovirus and Epstein-Barr virus, play an important role in the symptomatic periapical lesion. Indeed, periapical lesions may remain stable and silent until they become symptomatic, possibly triggered by the activation of latent herpesviruses within the lesion itself. Given the potential for grave systemic conditions associated with herpesvirus infection, early detection and treatment decisions for periapical lesions by the dentist may positively affect a patient’s overall health; especially for the immunocompromised patient.
PB  - Iris Publishers
T2  - Online Journal of Dentistry & Oral Health
T1  - Endodontic Periapical Disease: A Virus-Based Perspective
VL  - 2
IS  - 2
SP  - 1
EP  - 5
DO  - 10.33552/OJDOH.2019.02.000534
ER  - 

@article{
author = "Sabeti, Mohammad and Golchert, Kory J. and Shirgill, Neveed and Jakovljević, Aleksandar and Andrić, Miroslav and Milašin, Jelena",
year = "2019",
abstract = "There is a need for updating the current treatment modalities for periapical lesions of endodontic origin to reflect the contributions and potential morbidity from herpesvirus infection. Herpesviruses, particularly human cytomegalovirus and Epstein-Barr virus, play an important role in the symptomatic periapical lesion. Indeed, periapical lesions may remain stable and silent until they become symptomatic, possibly triggered by the activation of latent herpesviruses within the lesion itself. Given the potential for grave systemic conditions associated with herpesvirus infection, early detection and treatment decisions for periapical lesions by the dentist may positively affect a patient’s overall health; especially for the immunocompromised patient.",
publisher = "Iris Publishers",
journal = "Online Journal of Dentistry & Oral Health",
title = "Endodontic Periapical Disease: A Virus-Based Perspective",
volume = "2",
number = "2",
pages = "1-5",
doi = "10.33552/OJDOH.2019.02.000534"
}

Sabeti, M., Golchert, K. J., Shirgill, N., Jakovljević, A., Andrić, M.,& Milašin, J.. (2019). Endodontic Periapical Disease: A Virus-Based Perspective. in Online Journal of Dentistry & Oral Health
Iris Publishers., 2(2), 1-5.
https://doi.org/10.33552/OJDOH.2019.02.000534

Sabeti M, Golchert KJ, Shirgill N, Jakovljević A, Andrić M, Milašin J. Endodontic Periapical Disease: A Virus-Based Perspective. in Online Journal of Dentistry & Oral Health. 2019;2(2):1-5.
doi:10.33552/OJDOH.2019.02.000534 .

Sabeti, Mohammad, Golchert, Kory J., Shirgill, Neveed, Jakovljević, Aleksandar, Andrić, Miroslav, Milašin, Jelena, "Endodontic Periapical Disease: A Virus-Based Perspective" in Online Journal of Dentistry & Oral Health, 2, no. 2 (2019):1-5,
https://doi.org/10.33552/OJDOH.2019.02.000534 . .

TY  - JOUR
AU  - Jakovljević, Aleksandar
AU  - Andrić, Miroslav
AU  - Knežević, Aleksandra
AU  - Miletić, Maja
AU  - Beljić-Ivanović, Katarina
AU  - Milašin, Jelena
AU  - Sabeti, Mohammad
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2595
AB  - Purpose of Review
This review describes the most recent findings on herpesviral infections and offers current concepts of herpesviral role in the pathogenesis of periapical periodontitis.

Recent Findings
Thirty articles reported data on herpesviral infection in periapical periodontitis. Epstein-Barr virus and human cytomegalovirus are the most frequently detected herpesviruses in periapical samples. The main hypothesis postulates a bidirectional herpesviral-bacterial relationship in the etiopathogenesis of periapical periodontitis. A high heterogeneity of herpesviruses incidence was registered within the studies, in part, due to various methodological approaches used in laboratory testing, different inclusion criteria, study design, seroprevalence of herpesviruses, and sociodemographic characteristics of investigated populations.

Summary
Herpesviruses have been shown to potentially impair local host defense in periapical tissue. Although it has been demonstrated that endodontic pathogenic bacteria are able to reactivate herpesviruses, further, in vitro studies should provide more data on herpesviruses as a factor in the pathogenesis of the periapical pathoses. It is, therefore, necessary to investigate potential benefits of antiviral therapy in well-designed controlled longitudinal studies.
PB  - Springer
T2  - Current Oral Health Reports
T1  - Herpesviral Infection in Periapical Periodontitis
VL  - 5
IS  - 4
SP  - 255
EP  - 263
DO  - 10.1007/s40496-018-0198-7
ER  - 

@article{
author = "Jakovljević, Aleksandar and Andrić, Miroslav and Knežević, Aleksandra and Miletić, Maja and Beljić-Ivanović, Katarina and Milašin, Jelena and Sabeti, Mohammad",
year = "2018",
abstract = "Purpose of Review
This review describes the most recent findings on herpesviral infections and offers current concepts of herpesviral role in the pathogenesis of periapical periodontitis.

Recent Findings
Thirty articles reported data on herpesviral infection in periapical periodontitis. Epstein-Barr virus and human cytomegalovirus are the most frequently detected herpesviruses in periapical samples. The main hypothesis postulates a bidirectional herpesviral-bacterial relationship in the etiopathogenesis of periapical periodontitis. A high heterogeneity of herpesviruses incidence was registered within the studies, in part, due to various methodological approaches used in laboratory testing, different inclusion criteria, study design, seroprevalence of herpesviruses, and sociodemographic characteristics of investigated populations.

Summary
Herpesviruses have been shown to potentially impair local host defense in periapical tissue. Although it has been demonstrated that endodontic pathogenic bacteria are able to reactivate herpesviruses, further, in vitro studies should provide more data on herpesviruses as a factor in the pathogenesis of the periapical pathoses. It is, therefore, necessary to investigate potential benefits of antiviral therapy in well-designed controlled longitudinal studies.",
publisher = "Springer",
journal = "Current Oral Health Reports",
title = "Herpesviral Infection in Periapical Periodontitis",
volume = "5",
number = "4",
pages = "255-263",
doi = "10.1007/s40496-018-0198-7"
}

Jakovljević, A., Andrić, M., Knežević, A., Miletić, M., Beljić-Ivanović, K., Milašin, J.,& Sabeti, M.. (2018). Herpesviral Infection in Periapical Periodontitis. in Current Oral Health Reports
Springer., 5(4), 255-263.
https://doi.org/10.1007/s40496-018-0198-7

Jakovljević A, Andrić M, Knežević A, Miletić M, Beljić-Ivanović K, Milašin J, Sabeti M. Herpesviral Infection in Periapical Periodontitis. in Current Oral Health Reports. 2018;5(4):255-263.
doi:10.1007/s40496-018-0198-7 .

Jakovljević, Aleksandar, Andrić, Miroslav, Knežević, Aleksandra, Miletić, Maja, Beljić-Ivanović, Katarina, Milašin, Jelena, Sabeti, Mohammad, "Herpesviral Infection in Periapical Periodontitis" in Current Oral Health Reports, 5, no. 4 (2018):255-263,
https://doi.org/10.1007/s40496-018-0198-7 . .