TY  - JOUR
AU  - Janković, Saša
AU  - Aleksić, Zoran
AU  - Dimitrijević, Božidar
AU  - Camargo, Paulo
AU  - Kenney, Barrie
AU  - Leković, Vojislav
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1844
AB  - Risk factors such as smoking, genetic factors, and tissue biotype play an important role in the etiology, predictability, and long-term stability of gingival recession treatment. This study was designed to evaluate the influence of interleukin 1 (IL-1) polymorphism and smoking on the stability of gingival recession treatment after 1 and 3 years. All patients (n = 55) were treated for type I and II recession defects using a connective tissue graft. Clinical evaluations were performed, which included assessment of vertical recession depth, gingival inflammation, and clinical attachment level. A fingerstick blood sample was collected using specially provided DNA filter paper and mailed for processing in a laboratory using polymerase chain reaction-based methodology. The results indicated that 19 subjects were genotype positive (34.5%). Treatment of the localized recessions was effective and provided a similar amount of coverage in genotype-positive and genotype-negative subjects within smoking and nonsmoking groups after 1 year. In a 3-year period, nonsmoking patients with positive IL-1 genotype lost approximately 20% of the root coverage gained at 1 year and were almost four times more inferior compared with genotype-negative patients. Patients who smoked and had a positive IL-1 genotype lost approximately 35% of the gained root coverage. IL-1 polymorphism and smoking habit did not affect gingival recession treatment at 1 year but had a great impact on long-term stability.
PB  - Quintessence Publishing Co Inc, Hanover Park
T2  - International Journal of Periodontics & Restorative Dentistry
T1  - Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment
VL  - 33
IS  - 1
SP  - E16
EP  - E23
DO  - 10.11607/prd.0823
ER  - 

@article{
author = "Janković, Saša and Aleksić, Zoran and Dimitrijević, Božidar and Camargo, Paulo and Kenney, Barrie and Leković, Vojislav",
year = "2013",
abstract = "Risk factors such as smoking, genetic factors, and tissue biotype play an important role in the etiology, predictability, and long-term stability of gingival recession treatment. This study was designed to evaluate the influence of interleukin 1 (IL-1) polymorphism and smoking on the stability of gingival recession treatment after 1 and 3 years. All patients (n = 55) were treated for type I and II recession defects using a connective tissue graft. Clinical evaluations were performed, which included assessment of vertical recession depth, gingival inflammation, and clinical attachment level. A fingerstick blood sample was collected using specially provided DNA filter paper and mailed for processing in a laboratory using polymerase chain reaction-based methodology. The results indicated that 19 subjects were genotype positive (34.5%). Treatment of the localized recessions was effective and provided a similar amount of coverage in genotype-positive and genotype-negative subjects within smoking and nonsmoking groups after 1 year. In a 3-year period, nonsmoking patients with positive IL-1 genotype lost approximately 20% of the root coverage gained at 1 year and were almost four times more inferior compared with genotype-negative patients. Patients who smoked and had a positive IL-1 genotype lost approximately 35% of the gained root coverage. IL-1 polymorphism and smoking habit did not affect gingival recession treatment at 1 year but had a great impact on long-term stability.",
publisher = "Quintessence Publishing Co Inc, Hanover Park",
journal = "International Journal of Periodontics & Restorative Dentistry",
title = "Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment",
volume = "33",
number = "1",
pages = "E16-E23",
doi = "10.11607/prd.0823"
}

Janković, S., Aleksić, Z., Dimitrijević, B., Camargo, P., Kenney, B.,& Leković, V.. (2013). Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment. in International Journal of Periodontics & Restorative Dentistry
Quintessence Publishing Co Inc, Hanover Park., 33(1), E16-E23.
https://doi.org/10.11607/prd.0823

Janković S, Aleksić Z, Dimitrijević B, Camargo P, Kenney B, Leković V. Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment. in International Journal of Periodontics & Restorative Dentistry. 2013;33(1):E16-E23.
doi:10.11607/prd.0823 .

Janković, Saša, Aleksić, Zoran, Dimitrijević, Božidar, Camargo, Paulo, Kenney, Barrie, Leković, Vojislav, "Impact of Interleukin 1 Gene Polymorphism and Smoking on Long-Term Stability Following Gingival Recession Treatment" in International Journal of Periodontics & Restorative Dentistry, 33, no. 1 (2013):E16-E23,
https://doi.org/10.11607/prd.0823 . .

TY  - JOUR
AU  - Leković, Vojislav
AU  - Milinković, Iva
AU  - Aleksić, Zoran
AU  - Janković, Saša
AU  - Stanković, P.
AU  - Kenney, Barrie
AU  - Camargo, Paulo
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1762
AB  - Lekovic V, Milinkovic I, Aleksic Z, Jankovic S, Stankovic P, Kenney EB, Camargo PM. Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects. J Periodont Res 2012; 47: 409417. (c) 2011 John Wiley & Sons A/S Background and Objective: Bovine porous bone mineral (BPBM) is a xenograft that has been successfully utilized in periodontal regeneration. Platelet-rich fibrin (PRF) is a leukocyte and platelet preparation that concentrates various polypeptide growth factors and therefore has the potential to be used as regenerative treatment for periodontal defects. The purpose of this study was to examine the suitability of autologous PRF as regenerative treatment for periodontal intrabony defects in humans and to examine the ability of BPBM to augment the regenerative effects exerted by PRF. Material and Methods: Using a split-mouth design, 17 paired intrabony defects were randomly treated either with PRF or with PRFBPBM combination. Re-entry surgeries were performed at 6 mo. Primary study outcomes were changes in pocket depth, attachment level and defect fill. Results: Preoperative pocket depths, attachment levels and transoperative bone measurements were similar for the PRF and PRFBPBM groups. Postsurgical measurements revealed a significantly greater reduction in pocket depth in the PRFBPBM group (4.47 +/- 0.78 mm on buccal and 4.29 +/- 0.82 mm on lingual sites) when compared with the PRF group (3.35 +/- 0.68 mm on buccal and 3.24 +/- 0.73 mm on lingual sites). The PRFBPBM group presented with significantly greater attachment gain (3.82 +/- 0.78 mm on buccal and 3.71 +/- 0.75 mm on lingual sites) than the PRF group (2.24 +/- 0.73 mm on buccal and 2.12 +/- 0.68 mm on lingual sites). Defect fill was also greater in the PRFBPBM group (4.06 +/- 0.87 mm on buccal and 3.94 +/- 0.73 mm on lingual sites) than in the PRF group (2.21 +/- 0.68 mm on buccal and 2.06 +/- 0.64 mm on lingual sites). Conclusion: The results of this study indicate that PRF can improve clinical parameters associated with human intrabony periodontal defects, and BPBM has the ability to augment the effects of PRF in reducing pocket depth, improving clinical attachment levels and promoting defect fill.
PB  - Wiley, Hoboken
T2  - Journal of Periodontal Research
T1  - Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects
VL  - 47
IS  - 4
SP  - 409
EP  - 417
DO  - 10.1111/j.1600-0765.2011.01446.x
ER  - 

@article{
author = "Leković, Vojislav and Milinković, Iva and Aleksić, Zoran and Janković, Saša and Stanković, P. and Kenney, Barrie and Camargo, Paulo",
year = "2012",
abstract = "Lekovic V, Milinkovic I, Aleksic Z, Jankovic S, Stankovic P, Kenney EB, Camargo PM. Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects. J Periodont Res 2012; 47: 409417. (c) 2011 John Wiley & Sons A/S Background and Objective: Bovine porous bone mineral (BPBM) is a xenograft that has been successfully utilized in periodontal regeneration. Platelet-rich fibrin (PRF) is a leukocyte and platelet preparation that concentrates various polypeptide growth factors and therefore has the potential to be used as regenerative treatment for periodontal defects. The purpose of this study was to examine the suitability of autologous PRF as regenerative treatment for periodontal intrabony defects in humans and to examine the ability of BPBM to augment the regenerative effects exerted by PRF. Material and Methods: Using a split-mouth design, 17 paired intrabony defects were randomly treated either with PRF or with PRFBPBM combination. Re-entry surgeries were performed at 6 mo. Primary study outcomes were changes in pocket depth, attachment level and defect fill. Results: Preoperative pocket depths, attachment levels and transoperative bone measurements were similar for the PRF and PRFBPBM groups. Postsurgical measurements revealed a significantly greater reduction in pocket depth in the PRFBPBM group (4.47 +/- 0.78 mm on buccal and 4.29 +/- 0.82 mm on lingual sites) when compared with the PRF group (3.35 +/- 0.68 mm on buccal and 3.24 +/- 0.73 mm on lingual sites). The PRFBPBM group presented with significantly greater attachment gain (3.82 +/- 0.78 mm on buccal and 3.71 +/- 0.75 mm on lingual sites) than the PRF group (2.24 +/- 0.73 mm on buccal and 2.12 +/- 0.68 mm on lingual sites). Defect fill was also greater in the PRFBPBM group (4.06 +/- 0.87 mm on buccal and 3.94 +/- 0.73 mm on lingual sites) than in the PRF group (2.21 +/- 0.68 mm on buccal and 2.06 +/- 0.64 mm on lingual sites). Conclusion: The results of this study indicate that PRF can improve clinical parameters associated with human intrabony periodontal defects, and BPBM has the ability to augment the effects of PRF in reducing pocket depth, improving clinical attachment levels and promoting defect fill.",
publisher = "Wiley, Hoboken",
journal = "Journal of Periodontal Research",
title = "Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects",
volume = "47",
number = "4",
pages = "409-417",
doi = "10.1111/j.1600-0765.2011.01446.x"
}

Leković, V., Milinković, I., Aleksić, Z., Janković, S., Stanković, P., Kenney, B.,& Camargo, P.. (2012). Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects. in Journal of Periodontal Research
Wiley, Hoboken., 47(4), 409-417.
https://doi.org/10.1111/j.1600-0765.2011.01446.x

Leković V, Milinković I, Aleksić Z, Janković S, Stanković P, Kenney B, Camargo P. Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects. in Journal of Periodontal Research. 2012;47(4):409-417.
doi:10.1111/j.1600-0765.2011.01446.x .

Leković, Vojislav, Milinković, Iva, Aleksić, Zoran, Janković, Saša, Stanković, P., Kenney, Barrie, Camargo, Paulo, "Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects" in Journal of Periodontal Research, 47, no. 4 (2012):409-417,
https://doi.org/10.1111/j.1600-0765.2011.01446.x . .

TY  - JOUR
AU  - Janković, Saša
AU  - Aleksić, Zoran
AU  - Klokkevold, Perry
AU  - Leković, Vojislav
AU  - Dimitrijević, Božidar
AU  - Kenney, Barrie
AU  - Camargo, Paulo
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1690
AB  - This 6-month randomized controlled clinical study primarily aimed to compare the results achieved by the use of a platelet-rich fibrin (PRF) membrane or connective tissue graft (CTG) in the treatment of gingival recession and to evaluate the clinical impact of PRF on early wound healing and subjective patient discomfort. Use of a PRF membrane in gingival recession treatment provided acceptable clinical results, followed by enhanced wound healing and decreased subjective patient discomfort compared to CTG-treated gingival recessions. No difference could be found between PRF and CTG procedures in gingival recession therapy, except for a greater gain in keratinized tissue width obtained in the CTG group and enhanced wound healing associated with the PRF group. (Int J Periodontics Restorative Dent 2012;32:e41-e50.)
T2  - International Journal of Periodontics & Restorative Dentistry
T1  - Use of Platelet-Rich Fibrin Membrane Following Treatment of Gingival Recession: A Randomized Clinical Trial
VL  - 32
IS  - 2
SP  - e41
EP  - e50
UR  - https://hdl.handle.net/21.15107/rcub_smile_1690
ER  - 

@article{
author = "Janković, Saša and Aleksić, Zoran and Klokkevold, Perry and Leković, Vojislav and Dimitrijević, Božidar and Kenney, Barrie and Camargo, Paulo",
year = "2012",
abstract = "This 6-month randomized controlled clinical study primarily aimed to compare the results achieved by the use of a platelet-rich fibrin (PRF) membrane or connective tissue graft (CTG) in the treatment of gingival recession and to evaluate the clinical impact of PRF on early wound healing and subjective patient discomfort. Use of a PRF membrane in gingival recession treatment provided acceptable clinical results, followed by enhanced wound healing and decreased subjective patient discomfort compared to CTG-treated gingival recessions. No difference could be found between PRF and CTG procedures in gingival recession therapy, except for a greater gain in keratinized tissue width obtained in the CTG group and enhanced wound healing associated with the PRF group. (Int J Periodontics Restorative Dent 2012;32:e41-e50.)",
journal = "International Journal of Periodontics & Restorative Dentistry",
title = "Use of Platelet-Rich Fibrin Membrane Following Treatment of Gingival Recession: A Randomized Clinical Trial",
volume = "32",
number = "2",
pages = "e41-e50",
url = "https://hdl.handle.net/21.15107/rcub_smile_1690"
}

Janković, S., Aleksić, Z., Klokkevold, P., Leković, V., Dimitrijević, B., Kenney, B.,& Camargo, P.. (2012). Use of Platelet-Rich Fibrin Membrane Following Treatment of Gingival Recession: A Randomized Clinical Trial. in International Journal of Periodontics & Restorative Dentistry, 32(2), e41-e50.
https://hdl.handle.net/21.15107/rcub_smile_1690

Janković S, Aleksić Z, Klokkevold P, Leković V, Dimitrijević B, Kenney B, Camargo P. Use of Platelet-Rich Fibrin Membrane Following Treatment of Gingival Recession: A Randomized Clinical Trial. in International Journal of Periodontics & Restorative Dentistry. 2012;32(2):e41-e50.
https://hdl.handle.net/21.15107/rcub_smile_1690 .

Janković, Saša, Aleksić, Zoran, Klokkevold, Perry, Leković, Vojislav, Dimitrijević, Božidar, Kenney, Barrie, Camargo, Paulo, "Use of Platelet-Rich Fibrin Membrane Following Treatment of Gingival Recession: A Randomized Clinical Trial" in International Journal of Periodontics & Restorative Dentistry, 32, no. 2 (2012):e41-e50,
https://hdl.handle.net/21.15107/rcub_smile_1690 .

TY  - JOUR
AU  - Janković, Saša
AU  - Aleksić, Zoran
AU  - Dimitrijević, B.
AU  - Leković, Vojislav
AU  - Milinković, Iva
AU  - Kenney, Barrie
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1615
AB  - Background: The purpose of this study was to estimate the prevalence of different genotypes of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites, and to evaluate the correlation between herpesvirus presence and clinical parameters. Methods: A total of 80 dental implants ( mean time of loading, 4.16 +/- 1.8 years) were evaluated during the course of the study (30 peri-implantitis, 25 mucositis and 25 healthy peri-implant sites). The following clinical parameters were assessed: visible plaque index, bleeding on probing, suppuration and probing depth. A polymerase chain reaction (PCR) assay was used to identify the presence of different HCMV and EBV genotypes in peri-implant tissue plaque samples. Results: HCMV-2 was detected in 53.3% and EBV-1 in 46.6% of the 30 peri-implantitis sites evaluated. By contrast, HCMV-2 was not detected in healthy periodontal sites and EBV-1 was detected in one healthy site. A statistically significant correlation was found between the presence of HCMV-2 and EBV-1 genotypes and clinical parameters of peri-implantitis. Conclusions: The results from the present study confirmed the high prevalence of HCMV-2 and EBV-1 in the peri-implant tissue plaque of peri-implantitis sites and suggests a possible active pathogenic role of the viruses in peri-implantitis.
PB  - Wiley, Hoboken
T2  - Australian Dental Journal
T1  - Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status
VL  - 56
IS  - 4
SP  - 382
EP  - 388
DO  - 10.1111/j.1834-7819.2011.01360.x
ER  - 

@article{
author = "Janković, Saša and Aleksić, Zoran and Dimitrijević, B. and Leković, Vojislav and Milinković, Iva and Kenney, Barrie",
year = "2011",
abstract = "Background: The purpose of this study was to estimate the prevalence of different genotypes of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites, and to evaluate the correlation between herpesvirus presence and clinical parameters. Methods: A total of 80 dental implants ( mean time of loading, 4.16 +/- 1.8 years) were evaluated during the course of the study (30 peri-implantitis, 25 mucositis and 25 healthy peri-implant sites). The following clinical parameters were assessed: visible plaque index, bleeding on probing, suppuration and probing depth. A polymerase chain reaction (PCR) assay was used to identify the presence of different HCMV and EBV genotypes in peri-implant tissue plaque samples. Results: HCMV-2 was detected in 53.3% and EBV-1 in 46.6% of the 30 peri-implantitis sites evaluated. By contrast, HCMV-2 was not detected in healthy periodontal sites and EBV-1 was detected in one healthy site. A statistically significant correlation was found between the presence of HCMV-2 and EBV-1 genotypes and clinical parameters of peri-implantitis. Conclusions: The results from the present study confirmed the high prevalence of HCMV-2 and EBV-1 in the peri-implant tissue plaque of peri-implantitis sites and suggests a possible active pathogenic role of the viruses in peri-implantitis.",
publisher = "Wiley, Hoboken",
journal = "Australian Dental Journal",
title = "Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status",
volume = "56",
number = "4",
pages = "382-388",
doi = "10.1111/j.1834-7819.2011.01360.x"
}

Janković, S., Aleksić, Z., Dimitrijević, B., Leković, V., Milinković, I.,& Kenney, B.. (2011). Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status. in Australian Dental Journal
Wiley, Hoboken., 56(4), 382-388.
https://doi.org/10.1111/j.1834-7819.2011.01360.x

Janković S, Aleksić Z, Dimitrijević B, Leković V, Milinković I, Kenney B. Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status. in Australian Dental Journal. 2011;56(4):382-388.
doi:10.1111/j.1834-7819.2011.01360.x .

Janković, Saša, Aleksić, Zoran, Dimitrijević, B., Leković, Vojislav, Milinković, Iva, Kenney, Barrie, "Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status" in Australian Dental Journal, 56, no. 4 (2011):382-388,
https://doi.org/10.1111/j.1834-7819.2011.01360.x . .

TY  - JOUR
AU  - Janković, Saša
AU  - Aleksić, Zoran
AU  - Dimitrijević, B.
AU  - Leković, Vojislav
AU  - Camargo, Paulo
AU  - Kenney, Barrie
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1623
AB  - This study evaluated the prevalence of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites and the correlation between herpesvirus and clinical parameters. Fifty-six dental implants (mean time of loading, 4.27 +/- 1.6 years) were evaluated (20 peri-implantitis, 18 mucositis, 18 healthy pen-implant sites.) The clinical parameters assessed were: visible plaque index (PI), bleeding on probing (BOP), suppuration (SUP), probing depth (PD). A polymerase chain reaction assay identified HCMV and EBV in subgingival plaque samples. The percent of sites with plaque and BOP was significantly higher around mucositis and peri-implantitis compared with healthy implants (p  lt  0.05). The mean PD around the implants was significantly higher in peri-implantitis, followed by mucositis and healthy implants (p  lt  0.05). HCMV was detected in 13 (65%) and EBV in 9 (45%) of the 20 peri-implantitis sites. HCMV was found in 1 of the 18 (6%) healthy periodontal sites and EBV in 2 (11 %). A statistically significant correlation was found between presence of HCMV and EBV subgingivally and clinical parameters of peri-implantitis and healthy sites. These results confirm the high prevalence of HCMV and EBV in subgingival plaque of peri-implantitis sites and suggest the viruses have a possible active pathogenic role in peri-implantitis.
PB  - Churchill Livingstone, Edinburgh
T2  - International Journal of Oral & Maxillofacial Surgery
T1  - Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study
VL  - 40
IS  - 3
SP  - 271
EP  - 276
DO  - 10.1016/j.ijom.2010.11.004
ER  - 

@article{
author = "Janković, Saša and Aleksić, Zoran and Dimitrijević, B. and Leković, Vojislav and Camargo, Paulo and Kenney, Barrie",
year = "2011",
abstract = "This study evaluated the prevalence of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites and the correlation between herpesvirus and clinical parameters. Fifty-six dental implants (mean time of loading, 4.27 +/- 1.6 years) were evaluated (20 peri-implantitis, 18 mucositis, 18 healthy pen-implant sites.) The clinical parameters assessed were: visible plaque index (PI), bleeding on probing (BOP), suppuration (SUP), probing depth (PD). A polymerase chain reaction assay identified HCMV and EBV in subgingival plaque samples. The percent of sites with plaque and BOP was significantly higher around mucositis and peri-implantitis compared with healthy implants (p  lt  0.05). The mean PD around the implants was significantly higher in peri-implantitis, followed by mucositis and healthy implants (p  lt  0.05). HCMV was detected in 13 (65%) and EBV in 9 (45%) of the 20 peri-implantitis sites. HCMV was found in 1 of the 18 (6%) healthy periodontal sites and EBV in 2 (11 %). A statistically significant correlation was found between presence of HCMV and EBV subgingivally and clinical parameters of peri-implantitis and healthy sites. These results confirm the high prevalence of HCMV and EBV in subgingival plaque of peri-implantitis sites and suggest the viruses have a possible active pathogenic role in peri-implantitis.",
publisher = "Churchill Livingstone, Edinburgh",
journal = "International Journal of Oral & Maxillofacial Surgery",
title = "Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study",
volume = "40",
number = "3",
pages = "271-276",
doi = "10.1016/j.ijom.2010.11.004"
}

Janković, S., Aleksić, Z., Dimitrijević, B., Leković, V., Camargo, P.,& Kenney, B.. (2011). Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study. in International Journal of Oral & Maxillofacial Surgery
Churchill Livingstone, Edinburgh., 40(3), 271-276.
https://doi.org/10.1016/j.ijom.2010.11.004

Janković S, Aleksić Z, Dimitrijević B, Leković V, Camargo P, Kenney B. Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study. in International Journal of Oral & Maxillofacial Surgery. 2011;40(3):271-276.
doi:10.1016/j.ijom.2010.11.004 .

Janković, Saša, Aleksić, Zoran, Dimitrijević, B., Leković, Vojislav, Camargo, Paulo, Kenney, Barrie, "Prevalence of human cytomegalovirus and Epstein-Barr virus in subgingival plaque at peri-implantitis, mucositis and healthy sites. A pilot study" in International Journal of Oral & Maxillofacial Surgery, 40, no. 3 (2011):271-276,
https://doi.org/10.1016/j.ijom.2010.11.004 . .

TY  - JOUR
AU  - Pucar, Ana
AU  - Milašin, Jelena
AU  - Leković, Vojislav
AU  - Vukadinović, Miroslav
AU  - Ristić, Miljko
AU  - Putnik, Svetozar
AU  - Kenney, Barrie
PY  - 2007
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1349
AB  - Chronic infections, such as periodontitis, have been associated with an increase for atherosclerosis and coronary artery disease. The aim of this study was to investigate biopsy samples of coronary and internal mammary arteries for the presence of putative pathogenic bacteria (Porphyromanas gingivalis, Actinobacillus actinomycetemcomitans, Prevotella intermedia, and Tannerella forsythensis), Chlamydia pneumoniae, and human cytomegalovirus (CMV). Methods: Patients with a diagnosis of coronary artery disease were included in the study. fifteen coronary arteries with atherosclerosis and 15 internal mammary arteries without clinically assessable atherosclerotic degeneration were investigated. Both groups of specimens were obtained during coronary artery bypass grafting surgery. In all cases, the coronary and mammary artery specimens were taken from the same patient. The detection of periodontal pathogens, C. pneumoniae, and CMV was done by polymerase chain reaction analysis. Results: Bacterial DNA was found in nine of 15 (60%) coronary artery biopsy samples: P. gingivalis in eight (53.33%), A. actinomycetemcomitans in four (26.67%), P. intermedia in five (33.33%), and T. forsythensis in two (13.33%) samples; CMV was detected in 10 (66.67%) samples, and c. pneumoniae was detected in five (33.33%) samples. Some of the samples contained more than one type of bacteria. Periodontal pathogens were not detected in internal mammary artery biopsies, whereas CMV was present in seven (46.67%) samples and C. pneumoniae was present in six (40%) samples. Conclusion: The absence of putative pathogenic bacteria in internal mammary arteries, which are known to be affected rarely by atherosclerotic changes, and their presence in a high percentage of atherosclerotic coronary arteries support the concept that periodontal organisms are associated with the development and progression of atherosclerosis.
PB  - Wiley, Hoboken
T2  - Journal of Periodontology
T1  - Correlation between atherosclerosis and periodontal putative pathogenic bacterial infections in coronary and internal mammary arteries
VL  - 78
IS  - 4
SP  - 677
EP  - 682
DO  - 10.1902/jop.2007.060062
ER  - 

@article{
author = "Pucar, Ana and Milašin, Jelena and Leković, Vojislav and Vukadinović, Miroslav and Ristić, Miljko and Putnik, Svetozar and Kenney, Barrie",
year = "2007",
abstract = "Chronic infections, such as periodontitis, have been associated with an increase for atherosclerosis and coronary artery disease. The aim of this study was to investigate biopsy samples of coronary and internal mammary arteries for the presence of putative pathogenic bacteria (Porphyromanas gingivalis, Actinobacillus actinomycetemcomitans, Prevotella intermedia, and Tannerella forsythensis), Chlamydia pneumoniae, and human cytomegalovirus (CMV). Methods: Patients with a diagnosis of coronary artery disease were included in the study. fifteen coronary arteries with atherosclerosis and 15 internal mammary arteries without clinically assessable atherosclerotic degeneration were investigated. Both groups of specimens were obtained during coronary artery bypass grafting surgery. In all cases, the coronary and mammary artery specimens were taken from the same patient. The detection of periodontal pathogens, C. pneumoniae, and CMV was done by polymerase chain reaction analysis. Results: Bacterial DNA was found in nine of 15 (60%) coronary artery biopsy samples: P. gingivalis in eight (53.33%), A. actinomycetemcomitans in four (26.67%), P. intermedia in five (33.33%), and T. forsythensis in two (13.33%) samples; CMV was detected in 10 (66.67%) samples, and c. pneumoniae was detected in five (33.33%) samples. Some of the samples contained more than one type of bacteria. Periodontal pathogens were not detected in internal mammary artery biopsies, whereas CMV was present in seven (46.67%) samples and C. pneumoniae was present in six (40%) samples. Conclusion: The absence of putative pathogenic bacteria in internal mammary arteries, which are known to be affected rarely by atherosclerotic changes, and their presence in a high percentage of atherosclerotic coronary arteries support the concept that periodontal organisms are associated with the development and progression of atherosclerosis.",
publisher = "Wiley, Hoboken",
journal = "Journal of Periodontology",
title = "Correlation between atherosclerosis and periodontal putative pathogenic bacterial infections in coronary and internal mammary arteries",
volume = "78",
number = "4",
pages = "677-682",
doi = "10.1902/jop.2007.060062"
}

Pucar, A., Milašin, J., Leković, V., Vukadinović, M., Ristić, M., Putnik, S.,& Kenney, B.. (2007). Correlation between atherosclerosis and periodontal putative pathogenic bacterial infections in coronary and internal mammary arteries. in Journal of Periodontology
Wiley, Hoboken., 78(4), 677-682.
https://doi.org/10.1902/jop.2007.060062

Pucar A, Milašin J, Leković V, Vukadinović M, Ristić M, Putnik S, Kenney B. Correlation between atherosclerosis and periodontal putative pathogenic bacterial infections in coronary and internal mammary arteries. in Journal of Periodontology. 2007;78(4):677-682.
doi:10.1902/jop.2007.060062 .

Pucar, Ana, Milašin, Jelena, Leković, Vojislav, Vukadinović, Miroslav, Ristić, Miljko, Putnik, Svetozar, Kenney, Barrie, "Correlation between atherosclerosis and periodontal putative pathogenic bacterial infections in coronary and internal mammary arteries" in Journal of Periodontology, 78, no. 4 (2007):677-682,
https://doi.org/10.1902/jop.2007.060062 . .

TY  - JOUR
AU  - Leković, Vojislav
AU  - Camargo, PM
AU  - Weinlaender, Michael
AU  - Vasilić, N
AU  - Aleksić, Zoran
AU  - Kenney, Barrie
PY  - 2003
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1187
AB  - Objective: A combination of platelet-rich plasma (PRP), bovine porous bone mineral (BPBM) and guided tissue regeneration (GTR) has been shown to be effective as regenerative treatment for intrabony periodontal defects. The purpose of this study was to evaluate the effectiveness of PRP, BPBM and GTR used in combination as regenerative treatment for grade II molar furcation defects in humans. Material and methods: Using a split-mouth design, a total of 52 grade II mandibular molar furcation defects were treated either with PRP/BPBM/GTR (experimental group, n =26) or with an open flap debridement (control group, n =26). The primary outcomes evaluated in this study included changes in pocket depth, attachment level and re-entry bone levels (horizontal and vertical) between baseline and 6 months postoperatively. Results: The results showed that the experimental group presented with significantly greater pocket reduction (4.07+/-0.33 mm for experimental and 2.49+/-0.38 mm for control sites), gain in clinical attachment (3.29 +/- 0.42 mm for experimental and 1.68+/-0.31 mm for control sites), vertical defect fill (2.56+/- 0.36 mm for experimental and -0.19+/-0.02 for control sites) and horizontal defect fill (2.28+/-0.33 mm for experimental and 0.08+/-0.02 mm for control sites) than the control group. Conclusions: It was concluded that the PRP/BPBM/GTR combined technique is an effective modality of regenerative treatment for mandibular grade II furcation defects. Further studies are necessary to elucidate the role played by each component of the combined therapy in achieving these results.
PB  - Wiley, Hoboken
T2  - Journal of Clinical Periodontology
T1  - Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans
VL  - 30
IS  - 8
SP  - 746
EP  - 751
DO  - 10.1034/j.1600-051X.2003.00368.x
ER  - 

@article{
author = "Leković, Vojislav and Camargo, PM and Weinlaender, Michael and Vasilić, N and Aleksić, Zoran and Kenney, Barrie",
year = "2003",
abstract = "Objective: A combination of platelet-rich plasma (PRP), bovine porous bone mineral (BPBM) and guided tissue regeneration (GTR) has been shown to be effective as regenerative treatment for intrabony periodontal defects. The purpose of this study was to evaluate the effectiveness of PRP, BPBM and GTR used in combination as regenerative treatment for grade II molar furcation defects in humans. Material and methods: Using a split-mouth design, a total of 52 grade II mandibular molar furcation defects were treated either with PRP/BPBM/GTR (experimental group, n =26) or with an open flap debridement (control group, n =26). The primary outcomes evaluated in this study included changes in pocket depth, attachment level and re-entry bone levels (horizontal and vertical) between baseline and 6 months postoperatively. Results: The results showed that the experimental group presented with significantly greater pocket reduction (4.07+/-0.33 mm for experimental and 2.49+/-0.38 mm for control sites), gain in clinical attachment (3.29 +/- 0.42 mm for experimental and 1.68+/-0.31 mm for control sites), vertical defect fill (2.56+/- 0.36 mm for experimental and -0.19+/-0.02 for control sites) and horizontal defect fill (2.28+/-0.33 mm for experimental and 0.08+/-0.02 mm for control sites) than the control group. Conclusions: It was concluded that the PRP/BPBM/GTR combined technique is an effective modality of regenerative treatment for mandibular grade II furcation defects. Further studies are necessary to elucidate the role played by each component of the combined therapy in achieving these results.",
publisher = "Wiley, Hoboken",
journal = "Journal of Clinical Periodontology",
title = "Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans",
volume = "30",
number = "8",
pages = "746-751",
doi = "10.1034/j.1600-051X.2003.00368.x"
}

Leković, V., Camargo, P., Weinlaender, M., Vasilić, N., Aleksić, Z.,& Kenney, B.. (2003). Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans. in Journal of Clinical Periodontology
Wiley, Hoboken., 30(8), 746-751.
https://doi.org/10.1034/j.1600-051X.2003.00368.x

Leković V, Camargo P, Weinlaender M, Vasilić N, Aleksić Z, Kenney B. Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans. in Journal of Clinical Periodontology. 2003;30(8):746-751.
doi:10.1034/j.1600-051X.2003.00368.x .

Leković, Vojislav, Camargo, PM, Weinlaender, Michael, Vasilić, N, Aleksić, Zoran, Kenney, Barrie, "Effectiveness of a combination of platelet-rich plasma, bovine porous bone mineral and guided tissue regeneration in the treatment of mandibular grade II molar furcations in humans" in Journal of Clinical Periodontology, 30, no. 8 (2003):746-751,
https://doi.org/10.1034/j.1600-051X.2003.00368.x . .