TY  - JOUR
AU  - Živanović, Dušica
AU  - Šipetić, Sandra
AU  - Stamenković-Radak, Marina
AU  - Milašin, Jelena
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1527
AB  - Introduction Type 2 diabetes mellitus is a common multifactorial genetic syndrome, which is determined by several genes and environmental factors. The aim of the present study was to investigate the presence of risk factors for developing diabetes type 2 among diabetic individuals and to compare the presence of risk factors among diabetic individuals with and without positive family history for type 2 diabetes. Material and methods This study was conducted in Cuprija during the period from February to June 2002. The case group included 137 individuals having diagnosis type 2 diabetes. The control group included 129 subjects having the following diagnoses: hypertension, angina pectoris, chronic obstructive lung disease, gastric ulcer or duodenal ulcer. All participants were interviewed at the Medical Center Cuprija using structural questionnaire. The data were collected regarding demographic characteristics, exposure to various chemical and physical agents, stress, smoking, obesity, physical inactivity and family history of diabetes. In the statistical analysis chi square test was used. Results The diabetic individuals were statistically significantly older (40 and more years old) (p=0,000), and they came from rural areas more frequently (p=0,006) than the individuals without diabetes. Significantly more diabetics had lower educational level (p=0,000) and they were agriculture workers and housewives significantly more frequently (p=0,000) than nondiabetic individuals. Furthermore, obesity (p=0,000) and physical inactivity (p=0,003) were significantly more frequent among the diabetic individuals than the nondiabetics. The diabetic individuals had significanly (p=0,000) more numbers of relatives with diabetes mellitus type 2 than the nondiabetics. The diabetic individuals with positive family history of diabetes were significantly older (p=0,021) and more frequently from urban areas (p=0,018) than the diabetic individuals without the positive family history of diabetes. Also they were significantly less exposed to physical agents (p=0,004). Discussion In our study, like in many others, age, place of residence, education, occupation, obesity, physical inactivity, positive family history of diabetes type 2 and exposure to physical agents were identified as potential risk factors for diabetes type 2. Conclusion Different risk factors are probably responsible for developing type 2 diabetes among individuals with and without positive family history of type 2 diabetes.
AB  - Dijabetes tipa 2 jeste bolest koja nastaje kao rezultat interakcije genetičkih faktora i faktora sredine. Cilj ove studije bio je da se ispitaju faktori rizika koji utiču na nastajanje dijabetesa tipa 2 u populaciji Pomoravskog okruga, kao i da se analizira da li postoji razlika u faktorima rizika obolelih od dijabetesa bez pozitivne porodične anamneze i onih sa njom. U studiju je bilo uključeno 266 osoba iz Pomoravskog okruga, od kojih je 137 njih bilo sa dijabetesom melitusom tipa 2 i 129 sa nekim drugim oboljenjem (hipertenzija, angina pektoris, hronična opstruktivna bolest pluća, čir želuca ili čir dvanaestopalačnog creva). Osobe sa dijabetesom, u poređenju sa osobama bez dijabetesa, znatno su češće bile: starijeg uzrasta (40 i više godina starosti) (p=0,000), iz ruralne sredine (p=0,006), nižeg stepena obrazovanja (p=0,000), poljoprivrednici i domaćice (p=0,000), gojazne (p=0,000) i fizički neaktivne osobe (p=0,003) , a imale su i veći broj srodnika sa dijabetesom melitusom tipa 2 (p=0,000). Oboleli od dijabetesa sa pozitivnom porodičnom anamnezom za ovo oboljenje znatno su češće bile, starijeg uzrasta (p=0,021) i iz urbane sredine (p=0,018) od onih bez pozitivne porodične anamneze za dijabetes. Međutim, oboleli od dijabetesa bez pozitivne porodične anamneze za dijabetes znatno su češće (p=0,004) bili izloženi fizičkim agensima od onih koji su imali pozitivnu porodičnu anamnezu za ovo oboljenje.
PB  - Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad
T2  - Medicinski pregled
T1  - Potential risk factors for developing diabetes mellitus type 2
T1  - Potencijalni faktori rizika za nastajanje dijabetesa melitusa tipa 2
VL  - 63
IS  - 3-4
SP  - 231
EP  - 236
DO  - 10.2298/MPNS1004231Z
ER  - 

@article{
author = "Živanović, Dušica and Šipetić, Sandra and Stamenković-Radak, Marina and Milašin, Jelena",
year = "2010",
abstract = "Introduction Type 2 diabetes mellitus is a common multifactorial genetic syndrome, which is determined by several genes and environmental factors. The aim of the present study was to investigate the presence of risk factors for developing diabetes type 2 among diabetic individuals and to compare the presence of risk factors among diabetic individuals with and without positive family history for type 2 diabetes. Material and methods This study was conducted in Cuprija during the period from February to June 2002. The case group included 137 individuals having diagnosis type 2 diabetes. The control group included 129 subjects having the following diagnoses: hypertension, angina pectoris, chronic obstructive lung disease, gastric ulcer or duodenal ulcer. All participants were interviewed at the Medical Center Cuprija using structural questionnaire. The data were collected regarding demographic characteristics, exposure to various chemical and physical agents, stress, smoking, obesity, physical inactivity and family history of diabetes. In the statistical analysis chi square test was used. Results The diabetic individuals were statistically significantly older (40 and more years old) (p=0,000), and they came from rural areas more frequently (p=0,006) than the individuals without diabetes. Significantly more diabetics had lower educational level (p=0,000) and they were agriculture workers and housewives significantly more frequently (p=0,000) than nondiabetic individuals. Furthermore, obesity (p=0,000) and physical inactivity (p=0,003) were significantly more frequent among the diabetic individuals than the nondiabetics. The diabetic individuals had significanly (p=0,000) more numbers of relatives with diabetes mellitus type 2 than the nondiabetics. The diabetic individuals with positive family history of diabetes were significantly older (p=0,021) and more frequently from urban areas (p=0,018) than the diabetic individuals without the positive family history of diabetes. Also they were significantly less exposed to physical agents (p=0,004). Discussion In our study, like in many others, age, place of residence, education, occupation, obesity, physical inactivity, positive family history of diabetes type 2 and exposure to physical agents were identified as potential risk factors for diabetes type 2. Conclusion Different risk factors are probably responsible for developing type 2 diabetes among individuals with and without positive family history of type 2 diabetes., Dijabetes tipa 2 jeste bolest koja nastaje kao rezultat interakcije genetičkih faktora i faktora sredine. Cilj ove studije bio je da se ispitaju faktori rizika koji utiču na nastajanje dijabetesa tipa 2 u populaciji Pomoravskog okruga, kao i da se analizira da li postoji razlika u faktorima rizika obolelih od dijabetesa bez pozitivne porodične anamneze i onih sa njom. U studiju je bilo uključeno 266 osoba iz Pomoravskog okruga, od kojih je 137 njih bilo sa dijabetesom melitusom tipa 2 i 129 sa nekim drugim oboljenjem (hipertenzija, angina pektoris, hronična opstruktivna bolest pluća, čir želuca ili čir dvanaestopalačnog creva). Osobe sa dijabetesom, u poređenju sa osobama bez dijabetesa, znatno su češće bile: starijeg uzrasta (40 i više godina starosti) (p=0,000), iz ruralne sredine (p=0,006), nižeg stepena obrazovanja (p=0,000), poljoprivrednici i domaćice (p=0,000), gojazne (p=0,000) i fizički neaktivne osobe (p=0,003) , a imale su i veći broj srodnika sa dijabetesom melitusom tipa 2 (p=0,000). Oboleli od dijabetesa sa pozitivnom porodičnom anamnezom za ovo oboljenje znatno su češće bile, starijeg uzrasta (p=0,021) i iz urbane sredine (p=0,018) od onih bez pozitivne porodične anamneze za dijabetes. Međutim, oboleli od dijabetesa bez pozitivne porodične anamneze za dijabetes znatno su češće (p=0,004) bili izloženi fizičkim agensima od onih koji su imali pozitivnu porodičnu anamnezu za ovo oboljenje.",
publisher = "Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad",
journal = "Medicinski pregled",
title = "Potential risk factors for developing diabetes mellitus type 2, Potencijalni faktori rizika za nastajanje dijabetesa melitusa tipa 2",
volume = "63",
number = "3-4",
pages = "231-236",
doi = "10.2298/MPNS1004231Z"
}

Živanović, D., Šipetić, S., Stamenković-Radak, M.,& Milašin, J.. (2010). Potential risk factors for developing diabetes mellitus type 2. in Medicinski pregled
Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad., 63(3-4), 231-236.
https://doi.org/10.2298/MPNS1004231Z

Živanović D, Šipetić S, Stamenković-Radak M, Milašin J. Potential risk factors for developing diabetes mellitus type 2. in Medicinski pregled. 2010;63(3-4):231-236.
doi:10.2298/MPNS1004231Z .

Živanović, Dušica, Šipetić, Sandra, Stamenković-Radak, Marina, Milašin, Jelena, "Potential risk factors for developing diabetes mellitus type 2" in Medicinski pregled, 63, no. 3-4 (2010):231-236,
https://doi.org/10.2298/MPNS1004231Z . .

TY  - JOUR
AU  - Živanović, Dušica
AU  - Šipetić, Sandra
AU  - Stamenković-Radak, Marina
AU  - Milašin, Jelena
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1414
AB  - Background/Aim. Graves-Basedow disease is a common multifactorial genetic syndrome, which is determined by several genes and environmental factors. The aim of the present study was to investigate the presence of risk factors for developing Graves-Basedow disease between the groups of individuals with and without Graves-Basedow disease, and to compare the presence of risk factors between the affected individuals with or without positive family history for Graves- Basedow disease. Methods. This cross-sectional study was conducted in Ćuprija (central Serbia) during a period from December 2001 to April 2002. The case group comprised 132 individuals diagnosed with Graves-Basedow disease. The control group comprised 130 subjects without any of endocrine diseases. All participants were interviewed at the Medical Center Ćuprija using structural questionnaire. Data were collected on basic demographic characteristics, exposure to various chemical and physical agents, stress, smoking and family history of Graves-Basedow disease. In statistical analysis chi-square test was used. Results. The individuals with Graves-Basedow disease were statistically significantly older (above 50) (p = 0.020), exposed to stress (p = 0.024) and to physical agents (p = 0.031), and had significantly (p = 0.000) more relatives with Graves-Basedow disease than those without the disease. Among the affected individuals with positive family history of Graves-Basedow disease the number of women was significantly higher (p = 0.000), than the affected individuals without positive family history of Graves- Basedow disease. Conclusion. In our study, as in many other, gender, age, positive family history of Graves-Basedow disease and exposure to physical agents were identified as potential risk factors for the increased incidence of Graves- Basedow disease. Different risk factors are probably responsible for developing Graves-Basedow disease among the affected individuals with or without positive family history of Graves-Basedow disease. .
AB  - Uvod/Cilj. Grejvs-Bazedovljeva bolest nastaje kao rezultat interakcije između genetičkih faktora i faktora sredine. Cilj ovog rada bio je da se ispita prisustvo faktora rizika koji mogu da utiču na nastajanje Grejvs-Bazedovljeve bolesti kod populacije Pomoravskog okruga, kao i da se ispita da li postoji razlika u prisutnim faktorima rizika između obolelih od Grejvs- Bazedovljeve bolesti sa i bez pozitivne porodične anamneze ovog oboljenja. Metode. U studiju je bilo uključeno 350 osoba Pomoravskog okruga, od kojih je 132 bilo sa Grejvs- Bazedovljevom bolešću i 130 zdravih osoba, za koje je utvrđeno da nemaju endokrinološko oboljenje. U cilju procene izloženosti potencijalnim faktorima rizika od nastajanja Grejvs-Bazedovljeve bolesti koristili smo upitnik koji je sadržao pitanja koja su se odnosila na demografske karakteristike, pušenje, stres, izloženost hemijskim i fizičkim agensima na poslu i prisustvo pozitivne porodične anamneze Grejvs- Bazedovljeve bolesti za period pre dijagnostikovanja oboljenja. Rezultati. Osobe sa Grejvs-Bazedovljevom bolešću, u poređenju sa osobama bez Grejvs-Bazedovljeve bolesti, značajno češće bile su: starijeg uzrasta (50 i više godina) (p = 0,020), izložene stresu (p = 0,024) i fizičkim agensima na poslu (p = 0,031), sa pozitivnom porodičnom anamnezom Grejvs-Bazedovljeve bolesti i sa većim brojem prvo- i drugostepenih srodnika sa istim oboljenjem (p = 0,000). Oboleli od Grejvs-Bazedovljeve bolesti sa pozitivnom porodičnom anamnezom, nisu se statistički značajno razlikovali po izloženosti potencijalnim faktorima rizika u odnosu na obolele osobe bez pozitivne porodične anamneze Grejvs-Bazedovljeve bolesti, sem što su značajno češće u ovoj grupi bile žene (p = 0,000). Zaključak. Pol, uzrast, pozitivna porodična anamneza Grejvs-Bazedovljeve bolesti i izloženost fizičkim agensima identifikovani su kao potencijalni faktori rizika od Grejvs- Bazedovljeve bolesti. Različiti faktori rizika verovatno su odgovorni za nastanak Grejvs-Bazedovljeve bolesti kod obolelih osoba sa i bez pozitivne porodične istorije ovog oboljenja. .
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Graves-Basedow disease and potential risk factors
T1  - Grejvs-Bazedovljeva bolest i potencijalni faktori rizika
VL  - 65
IS  - 8
SP  - 633
EP  - 638
DO  - 10.2298/VSP0808633Z
ER  - 

@article{
author = "Živanović, Dušica and Šipetić, Sandra and Stamenković-Radak, Marina and Milašin, Jelena",
year = "2008",
abstract = "Background/Aim. Graves-Basedow disease is a common multifactorial genetic syndrome, which is determined by several genes and environmental factors. The aim of the present study was to investigate the presence of risk factors for developing Graves-Basedow disease between the groups of individuals with and without Graves-Basedow disease, and to compare the presence of risk factors between the affected individuals with or without positive family history for Graves- Basedow disease. Methods. This cross-sectional study was conducted in Ćuprija (central Serbia) during a period from December 2001 to April 2002. The case group comprised 132 individuals diagnosed with Graves-Basedow disease. The control group comprised 130 subjects without any of endocrine diseases. All participants were interviewed at the Medical Center Ćuprija using structural questionnaire. Data were collected on basic demographic characteristics, exposure to various chemical and physical agents, stress, smoking and family history of Graves-Basedow disease. In statistical analysis chi-square test was used. Results. The individuals with Graves-Basedow disease were statistically significantly older (above 50) (p = 0.020), exposed to stress (p = 0.024) and to physical agents (p = 0.031), and had significantly (p = 0.000) more relatives with Graves-Basedow disease than those without the disease. Among the affected individuals with positive family history of Graves-Basedow disease the number of women was significantly higher (p = 0.000), than the affected individuals without positive family history of Graves- Basedow disease. Conclusion. In our study, as in many other, gender, age, positive family history of Graves-Basedow disease and exposure to physical agents were identified as potential risk factors for the increased incidence of Graves- Basedow disease. Different risk factors are probably responsible for developing Graves-Basedow disease among the affected individuals with or without positive family history of Graves-Basedow disease. ., Uvod/Cilj. Grejvs-Bazedovljeva bolest nastaje kao rezultat interakcije između genetičkih faktora i faktora sredine. Cilj ovog rada bio je da se ispita prisustvo faktora rizika koji mogu da utiču na nastajanje Grejvs-Bazedovljeve bolesti kod populacije Pomoravskog okruga, kao i da se ispita da li postoji razlika u prisutnim faktorima rizika između obolelih od Grejvs- Bazedovljeve bolesti sa i bez pozitivne porodične anamneze ovog oboljenja. Metode. U studiju je bilo uključeno 350 osoba Pomoravskog okruga, od kojih je 132 bilo sa Grejvs- Bazedovljevom bolešću i 130 zdravih osoba, za koje je utvrđeno da nemaju endokrinološko oboljenje. U cilju procene izloženosti potencijalnim faktorima rizika od nastajanja Grejvs-Bazedovljeve bolesti koristili smo upitnik koji je sadržao pitanja koja su se odnosila na demografske karakteristike, pušenje, stres, izloženost hemijskim i fizičkim agensima na poslu i prisustvo pozitivne porodične anamneze Grejvs- Bazedovljeve bolesti za period pre dijagnostikovanja oboljenja. Rezultati. Osobe sa Grejvs-Bazedovljevom bolešću, u poređenju sa osobama bez Grejvs-Bazedovljeve bolesti, značajno češće bile su: starijeg uzrasta (50 i više godina) (p = 0,020), izložene stresu (p = 0,024) i fizičkim agensima na poslu (p = 0,031), sa pozitivnom porodičnom anamnezom Grejvs-Bazedovljeve bolesti i sa većim brojem prvo- i drugostepenih srodnika sa istim oboljenjem (p = 0,000). Oboleli od Grejvs-Bazedovljeve bolesti sa pozitivnom porodičnom anamnezom, nisu se statistički značajno razlikovali po izloženosti potencijalnim faktorima rizika u odnosu na obolele osobe bez pozitivne porodične anamneze Grejvs-Bazedovljeve bolesti, sem što su značajno češće u ovoj grupi bile žene (p = 0,000). Zaključak. Pol, uzrast, pozitivna porodična anamneza Grejvs-Bazedovljeve bolesti i izloženost fizičkim agensima identifikovani su kao potencijalni faktori rizika od Grejvs- Bazedovljeve bolesti. Različiti faktori rizika verovatno su odgovorni za nastanak Grejvs-Bazedovljeve bolesti kod obolelih osoba sa i bez pozitivne porodične istorije ovog oboljenja. .",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Graves-Basedow disease and potential risk factors, Grejvs-Bazedovljeva bolest i potencijalni faktori rizika",
volume = "65",
number = "8",
pages = "633-638",
doi = "10.2298/VSP0808633Z"
}

Živanović, D., Šipetić, S., Stamenković-Radak, M.,& Milašin, J.. (2008). Graves-Basedow disease and potential risk factors. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 65(8), 633-638.
https://doi.org/10.2298/VSP0808633Z

Živanović D, Šipetić S, Stamenković-Radak M, Milašin J. Graves-Basedow disease and potential risk factors. in Vojnosanitetski pregled. 2008;65(8):633-638.
doi:10.2298/VSP0808633Z .

Živanović, Dušica, Šipetić, Sandra, Stamenković-Radak, Marina, Milašin, Jelena, "Graves-Basedow disease and potential risk factors" in Vojnosanitetski pregled, 65, no. 8 (2008):633-638,
https://doi.org/10.2298/VSP0808633Z . .