Jakovljević, Nikola

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Fluoride release from conventional, resin-modified and hybrid glass ionomer cements

Ležaja-Zebić, Maja; Jakovljević, Nikola; Miletić, Vesna

(Srpsko lekarsko društvo - Stomatološka sekcija, Beograd, 2018)

TY  - JOUR
AU  - Ležaja-Zebić, Maja
AU  - Jakovljević, Nikola
AU  - Miletić, Vesna
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2361
AB  - Introduction the aim of the study was to quantify and compare fluoride release from four different glass ionomer cement products (GICs). Materials and Methods Standardized disk-shaped samples (5x2mm; n=5/group) of GIC restorative materials: conventional (Fuji IX, GC Corp., Japan), resin-modified (Fuji II LC, GC) and hybrid glass ionomer cement (Equia Forte, GC) and a conventional GIC liner/base material (Alfagal, Galenika, Serbia) were tested for fluoride release up to 21 days post-setting. Each sample was immersed in 5 mL of fresh deionized water during each time interval. Universal microhybrid composite (Filtek Z250, 3M EPSE, USA) and adhesive (Adper Single Bond, 3M ESPE) were used as negative controls. Fluoride release was measured using an F-selective electrode (Cole-Parmer, USA) and an ion meter (Oakton 700, Cole-Parmer, USA). Data were statistically analyzed using one-way ANOVA, regression and correlation analysis at 0.05. Results the highest total fluoride release was measured from Alfagal (386±61 ppm/g), and significantly less from Equia (188±29 ppm/g), Fuji IX (143±11 ppm/g) and Fuji II LC (104±14 ppm/g) (p  lt  0.05). All GICs showed the highest fluoride release during the first 24 hours post-setting. After 3 days, fluoride release slowed down reaching a plateau for all materials. Regression and Pearson correlation analysis showed significant inverse relationship between fluoride release and sample mass and density (p lt 0.001). Conclusion of the three GICs indicated for use as restorative materials, Equia Forte released the highest fluoride concentration. Fluoride release was material and density dependent, with higher release occurring from lower density GICs.
AB  - Uvod Cilj ovog istraživanja je bio da se kvantifikuje i uporedi otpuštanje fluorida iz četiri glasjonomer cementa (GJC). Materijal i metode Napravljeni su standardizovani diskovi (5 × 2 mm; n = 5/grupa) od sledećih GJC: konvencionalnih (Fuji IX, GC Corp., Japan), smolom modifikovani (Fuji II LC, GC), hibridni GJC (Equia Forte, GC) i konvencionalni GJC lajner/baza (Alfagal, Galenika, Srbija). Ispitivano je otpuštanje fluorida tokom 21 dana tako što je svaki uzorak potapan u 5 ml sveže destilovane vode posle svakog mernog intervala. Univerzalni mikrohibridni kompozit (Filtek Z250, 3M EPSE, USA) i adheziv (Adper Single Bond, 3M ESPE) korišćeni su kao negativne kontrole. Otpuštanje fluorida je očitavano pomoću fluor-selektivne elektrode (Cole-Parmer, USA) i jon-metra (Oakton 700, Cole-Parmer, USA). Rezultati su statistički obrađeni ANOVA testom, regresionim i korelacionim analizama sa α = 0,05. Rezultati Ukupno otpuštanje fluorida je bilo najveće iz Alfagala (386 ± 61 ppm/g), značajno manje iz Equia Forte (188 ± 29 ppm/g), Fuji IX (143 ± 11 ppm/g), a najmanje iz Fuji II LC (104 ± 14 ppm/g) (p  lt  0,05). Svi GJC pokazali su najveće otpuštanje fluorida u toku prva 24 h po vezivanju. Posle tri dana otpuštanje fluorida je postajalo sporije dostižući plato za sva četiri materijala. Regresiona i Pirsonova korelaciona analiza pokazale su značajan obrnut odnos između otpuštanja fluorida i mase i gustine uzoraka (p  lt  0,001). Zaključak Od GJC indikovanih za ispune, Equia Forte je otpustila najveću koncentraciju fluorida. Otpuštanje fluorida zavisi od materijala i njegove gustine, pri čemu GJC manje gustine otpuštaju više fluorida.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Fluoride release from conventional, resin-modified and hybrid glass ionomer cements
T1  - Otpuštanje fluorida iz konvencionalnih, smolom modifikovanih i hibridnih glas-jonomer cemenata
VL  - 65
IS  - 4
SP  - 187
EP  - 194
UR  - https://hdl.handle.net/21.15107/rcub_smile_2361
ER  - 
@article{
author = "Ležaja-Zebić, Maja and Jakovljević, Nikola and Miletić, Vesna",
year = "2018",
abstract = "Introduction the aim of the study was to quantify and compare fluoride release from four different glass ionomer cement products (GICs). Materials and Methods Standardized disk-shaped samples (5x2mm; n=5/group) of GIC restorative materials: conventional (Fuji IX, GC Corp., Japan), resin-modified (Fuji II LC, GC) and hybrid glass ionomer cement (Equia Forte, GC) and a conventional GIC liner/base material (Alfagal, Galenika, Serbia) were tested for fluoride release up to 21 days post-setting. Each sample was immersed in 5 mL of fresh deionized water during each time interval. Universal microhybrid composite (Filtek Z250, 3M EPSE, USA) and adhesive (Adper Single Bond, 3M ESPE) were used as negative controls. Fluoride release was measured using an F-selective electrode (Cole-Parmer, USA) and an ion meter (Oakton 700, Cole-Parmer, USA). Data were statistically analyzed using one-way ANOVA, regression and correlation analysis at 0.05. Results the highest total fluoride release was measured from Alfagal (386±61 ppm/g), and significantly less from Equia (188±29 ppm/g), Fuji IX (143±11 ppm/g) and Fuji II LC (104±14 ppm/g) (p  lt  0.05). All GICs showed the highest fluoride release during the first 24 hours post-setting. After 3 days, fluoride release slowed down reaching a plateau for all materials. Regression and Pearson correlation analysis showed significant inverse relationship between fluoride release and sample mass and density (p lt 0.001). Conclusion of the three GICs indicated for use as restorative materials, Equia Forte released the highest fluoride concentration. Fluoride release was material and density dependent, with higher release occurring from lower density GICs., Uvod Cilj ovog istraživanja je bio da se kvantifikuje i uporedi otpuštanje fluorida iz četiri glasjonomer cementa (GJC). Materijal i metode Napravljeni su standardizovani diskovi (5 × 2 mm; n = 5/grupa) od sledećih GJC: konvencionalnih (Fuji IX, GC Corp., Japan), smolom modifikovani (Fuji II LC, GC), hibridni GJC (Equia Forte, GC) i konvencionalni GJC lajner/baza (Alfagal, Galenika, Srbija). Ispitivano je otpuštanje fluorida tokom 21 dana tako što je svaki uzorak potapan u 5 ml sveže destilovane vode posle svakog mernog intervala. Univerzalni mikrohibridni kompozit (Filtek Z250, 3M EPSE, USA) i adheziv (Adper Single Bond, 3M ESPE) korišćeni su kao negativne kontrole. Otpuštanje fluorida je očitavano pomoću fluor-selektivne elektrode (Cole-Parmer, USA) i jon-metra (Oakton 700, Cole-Parmer, USA). Rezultati su statistički obrađeni ANOVA testom, regresionim i korelacionim analizama sa α = 0,05. Rezultati Ukupno otpuštanje fluorida je bilo najveće iz Alfagala (386 ± 61 ppm/g), značajno manje iz Equia Forte (188 ± 29 ppm/g), Fuji IX (143 ± 11 ppm/g), a najmanje iz Fuji II LC (104 ± 14 ppm/g) (p  lt  0,05). Svi GJC pokazali su najveće otpuštanje fluorida u toku prva 24 h po vezivanju. Posle tri dana otpuštanje fluorida je postajalo sporije dostižući plato za sva četiri materijala. Regresiona i Pirsonova korelaciona analiza pokazale su značajan obrnut odnos između otpuštanja fluorida i mase i gustine uzoraka (p  lt  0,001). Zaključak Od GJC indikovanih za ispune, Equia Forte je otpustila najveću koncentraciju fluorida. Otpuštanje fluorida zavisi od materijala i njegove gustine, pri čemu GJC manje gustine otpuštaju više fluorida.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Fluoride release from conventional, resin-modified and hybrid glass ionomer cements, Otpuštanje fluorida iz konvencionalnih, smolom modifikovanih i hibridnih glas-jonomer cemenata",
volume = "65",
number = "4",
pages = "187-194",
url = "https://hdl.handle.net/21.15107/rcub_smile_2361"
}
Ležaja-Zebić, M., Jakovljević, N.,& Miletić, V.. (2018). Fluoride release from conventional, resin-modified and hybrid glass ionomer cements. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 65(4), 187-194.
https://hdl.handle.net/21.15107/rcub_smile_2361
Ležaja-Zebić M, Jakovljević N, Miletić V. Fluoride release from conventional, resin-modified and hybrid glass ionomer cements. in Stomatološki glasnik Srbije. 2018;65(4):187-194.
https://hdl.handle.net/21.15107/rcub_smile_2361 .
Ležaja-Zebić, Maja, Jakovljević, Nikola, Miletić, Vesna, "Fluoride release from conventional, resin-modified and hybrid glass ionomer cements" in Stomatološki glasnik Srbije, 65, no. 4 (2018):187-194,
https://hdl.handle.net/21.15107/rcub_smile_2361 .

Refractive indices of unfilled resin mixtures and cured composites related to color and translucency of conventional and low-shrinkage composites

Miletić, Vesna; Jakovljević, Nikola; Manojlović, Dragica; Marjanović, Jovana; Rosić, Aleksandra A.; Dramićanin, Miroslav D.

(Wiley-Blackwell, Hoboken, 2017)

TY  - JOUR
AU  - Miletić, Vesna
AU  - Jakovljević, Nikola
AU  - Manojlović, Dragica
AU  - Marjanović, Jovana
AU  - Rosić, Aleksandra A.
AU  - Dramićanin, Miroslav D.
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2199
AB  - This study correlated the refractive indices (RIs) of unfilled resin mixtures and resin-based composites (RBCs) with color and translucency of conventional and low-shrinkage RBCs. Unfilled resin mixtures based on different ratios of conventional monomers Bisphenol A-glycidyl-methacrylate (BisGMA)/triethyleneglycol-dimethacrylate (TEGDMA) and urethane-dimethacrylate (UDMA)/TEGDMA and a low-shrinkage monomer FIT-852 (FIT, Esstech Inc.)/TEGDMA were used to prepare model RBCs, containing 30 wt % of the organic matrix and 70 wt % of silanated barium-glass fillers (n=1.553, Esstech Inc.). The RIs of resins were measured on an ABBE refractometer, those of cured RBCs using the Becke-line method in immersion oils. Color and translucency were determined using an AvaSpec-2048 (Avantes BV) spectrometer. The RIs of unfilled resin mixtures decreased with increasing amounts of TEGDMA. Cured RBCs had higher RIs than their respective resin mixtures. BisGMA-based composites were more translucent with significantly lower L* values than FIT- and UDMA-based RBCs. The RIs of unfilled resins positively correlated with cured RBCs (p=0.001), as did the RIs with translucency (p=0.001) and color (p=0.008). Resin mixtures and corresponding RBCs based on UDMA and its modified low-shrinkage version, FIT, showed similar optical properties. The RIs of unfilled resins appeared to be good predictors of the RIs of cured RBCs.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Biomedical Materials Research Part B: Applied Biomaterials
T1  - Refractive indices of unfilled resin mixtures and cured composites related to color and translucency of conventional and low-shrinkage composites
VL  - 105
IS  - 1
SP  - 7
EP  - 13
DO  - 10.1002/jbm.b.33523
ER  - 
@article{
author = "Miletić, Vesna and Jakovljević, Nikola and Manojlović, Dragica and Marjanović, Jovana and Rosić, Aleksandra A. and Dramićanin, Miroslav D.",
year = "2017",
abstract = "This study correlated the refractive indices (RIs) of unfilled resin mixtures and resin-based composites (RBCs) with color and translucency of conventional and low-shrinkage RBCs. Unfilled resin mixtures based on different ratios of conventional monomers Bisphenol A-glycidyl-methacrylate (BisGMA)/triethyleneglycol-dimethacrylate (TEGDMA) and urethane-dimethacrylate (UDMA)/TEGDMA and a low-shrinkage monomer FIT-852 (FIT, Esstech Inc.)/TEGDMA were used to prepare model RBCs, containing 30 wt % of the organic matrix and 70 wt % of silanated barium-glass fillers (n=1.553, Esstech Inc.). The RIs of resins were measured on an ABBE refractometer, those of cured RBCs using the Becke-line method in immersion oils. Color and translucency were determined using an AvaSpec-2048 (Avantes BV) spectrometer. The RIs of unfilled resin mixtures decreased with increasing amounts of TEGDMA. Cured RBCs had higher RIs than their respective resin mixtures. BisGMA-based composites were more translucent with significantly lower L* values than FIT- and UDMA-based RBCs. The RIs of unfilled resins positively correlated with cured RBCs (p=0.001), as did the RIs with translucency (p=0.001) and color (p=0.008). Resin mixtures and corresponding RBCs based on UDMA and its modified low-shrinkage version, FIT, showed similar optical properties. The RIs of unfilled resins appeared to be good predictors of the RIs of cured RBCs.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Biomedical Materials Research Part B: Applied Biomaterials",
title = "Refractive indices of unfilled resin mixtures and cured composites related to color and translucency of conventional and low-shrinkage composites",
volume = "105",
number = "1",
pages = "7-13",
doi = "10.1002/jbm.b.33523"
}
Miletić, V., Jakovljević, N., Manojlović, D., Marjanović, J., Rosić, A. A.,& Dramićanin, M. D.. (2017). Refractive indices of unfilled resin mixtures and cured composites related to color and translucency of conventional and low-shrinkage composites. in Journal of Biomedical Materials Research Part B: Applied Biomaterials
Wiley-Blackwell, Hoboken., 105(1), 7-13.
https://doi.org/10.1002/jbm.b.33523
Miletić V, Jakovljević N, Manojlović D, Marjanović J, Rosić AA, Dramićanin MD. Refractive indices of unfilled resin mixtures and cured composites related to color and translucency of conventional and low-shrinkage composites. in Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2017;105(1):7-13.
doi:10.1002/jbm.b.33523 .
Miletić, Vesna, Jakovljević, Nikola, Manojlović, Dragica, Marjanović, Jovana, Rosić, Aleksandra A., Dramićanin, Miroslav D., "Refractive indices of unfilled resin mixtures and cured composites related to color and translucency of conventional and low-shrinkage composites" in Journal of Biomedical Materials Research Part B: Applied Biomaterials, 105, no. 1 (2017):7-13,
https://doi.org/10.1002/jbm.b.33523 . .
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Kvantifikacija otpuštanja fluorida iz konvencionalnih, smolom modifikovanih i hibridnih glas-jonomer cemenata

Jakovljević, Nikola

(Univerzitet u Beogradu, Stomatološki fakultet, 2017)

TY  - THES
AU  - Jakovljević, Nikola
PY  - 2017
UR  - https://plus.sr.cobiss.net/opac7/bib/1024300430
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/763
AB  - Uvod: Usavršavanje GJC obuhvata različite modifikacije u strukturi koje ne bi trebalo
da utiču na otpuštanje fluorida iz GJC.
Cilj rada: Kvantifikovati otpuštanje fluorida iz konvencionalnih, smolom modifikovanih
i hibridnih GJC.
Materijal i metode: Korišćeni su konvencionalni GJC Alfagal (Galenika) i Fuji IX
(GC), smolom-modifikovani Fuji II LC (GC) i hibridni Equia Forte (GC). Kontrole su
bile kompozit Filtek Z250 (3M) i adheziv Adper Single Bond (3M). Od svakog GJC i
kompozita napravljeno je po pet, a od adheziva jedan cilindričan uzorak, prečnika 5 i
visine 2 mm. Nakon inkubacije na suvom 24h (37°C) uzorci su potopljeni u po 5 mL
destilovane vode. Koncentracija fluorida je merena jon-metrom (Oakton Ion 700) sa
fluor-selektivnom elektrodom (Cole-Parmer) nakon 1, 6, 24 h, 3, 7, 14, 21 dana. Pre
merenja elektroda je kalibrisana standardima (0,1, 1 i 10 ppmF). Rezultati su statistički
obrađeni ANOVA testom sa α=0,05.
Rezultati: Maksimum otpuštanja fluorida je varirao između 7-14. dana (Alfagal), 24
sata i 3. dana (Fuji IX), 6-24. sata (Equia Forte), 14-21. dana (Fuji II LC). Postojala je
statistički značajna razlika između svih grupa GJC (p<0,05). Najveće ukupno otpuštanje
fluorida je pokazao Alfagal (36,44 ppmF), zatim Equia Forte (20,56 ppmF) i Fuji IX
(16,1 ppmF), a najmanje Fuji II LC (12,12 ppmF). Ukupno otpuštenje fluorida iz
kompozita i adheziva je zanemarljivo (0,01 i 0,02 ppmF, respektivno). 
Zaključak: Ispitivani GJC su pokazali trend kontinuranog otpuštanja fluorida, ali u
različitim koncentracijama u zavisnosti od vrste tečne komponente. Dodatak smole
negativno utiče na otpuštanje fluorida.
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Kvantifikacija otpuštanja fluorida iz konvencionalnih, smolom modifikovanih i hibridnih glas-jonomer cemenata
UR  - https://hdl.handle.net/21.15107/rcub_smile_763
ER  - 
@misc{
author = "Jakovljević, Nikola",
year = "2017",
abstract = "Uvod: Usavršavanje GJC obuhvata različite modifikacije u strukturi koje ne bi trebalo
da utiču na otpuštanje fluorida iz GJC.
Cilj rada: Kvantifikovati otpuštanje fluorida iz konvencionalnih, smolom modifikovanih
i hibridnih GJC.
Materijal i metode: Korišćeni su konvencionalni GJC Alfagal (Galenika) i Fuji IX
(GC), smolom-modifikovani Fuji II LC (GC) i hibridni Equia Forte (GC). Kontrole su
bile kompozit Filtek Z250 (3M) i adheziv Adper Single Bond (3M). Od svakog GJC i
kompozita napravljeno je po pet, a od adheziva jedan cilindričan uzorak, prečnika 5 i
visine 2 mm. Nakon inkubacije na suvom 24h (37°C) uzorci su potopljeni u po 5 mL
destilovane vode. Koncentracija fluorida je merena jon-metrom (Oakton Ion 700) sa
fluor-selektivnom elektrodom (Cole-Parmer) nakon 1, 6, 24 h, 3, 7, 14, 21 dana. Pre
merenja elektroda je kalibrisana standardima (0,1, 1 i 10 ppmF). Rezultati su statistički
obrađeni ANOVA testom sa α=0,05.
Rezultati: Maksimum otpuštanja fluorida je varirao između 7-14. dana (Alfagal), 24
sata i 3. dana (Fuji IX), 6-24. sata (Equia Forte), 14-21. dana (Fuji II LC). Postojala je
statistički značajna razlika između svih grupa GJC (p<0,05). Najveće ukupno otpuštanje
fluorida je pokazao Alfagal (36,44 ppmF), zatim Equia Forte (20,56 ppmF) i Fuji IX
(16,1 ppmF), a najmanje Fuji II LC (12,12 ppmF). Ukupno otpuštenje fluorida iz
kompozita i adheziva je zanemarljivo (0,01 i 0,02 ppmF, respektivno). 
Zaključak: Ispitivani GJC su pokazali trend kontinuranog otpuštanja fluorida, ali u
različitim koncentracijama u zavisnosti od vrste tečne komponente. Dodatak smole
negativno utiče na otpuštanje fluorida.",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Kvantifikacija otpuštanja fluorida iz konvencionalnih, smolom modifikovanih i hibridnih glas-jonomer cemenata",
url = "https://hdl.handle.net/21.15107/rcub_smile_763"
}
Jakovljević, N.. (2017). Kvantifikacija otpuštanja fluorida iz konvencionalnih, smolom modifikovanih i hibridnih glas-jonomer cemenata. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_763
Jakovljević N. Kvantifikacija otpuštanja fluorida iz konvencionalnih, smolom modifikovanih i hibridnih glas-jonomer cemenata. 2017;.
https://hdl.handle.net/21.15107/rcub_smile_763 .
Jakovljević, Nikola, "Kvantifikacija otpuštanja fluorida iz konvencionalnih, smolom modifikovanih i hibridnih glas-jonomer cemenata" (2017),
https://hdl.handle.net/21.15107/rcub_smile_763 .