Tabaković, Saša Z.

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  • Tabaković, Saša Z. (4)
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Prevalence, characteristics and severity of hypomineralization of the first permanent molars and incisors in children from the northern part of Kosovo and Metohija

Martinović, Brankica; Ivanović, Mirjana; Cvetković, Andrijana; Todić, Jelena; Milojković, Zoraida; Pavlović, Jasna; Tabaković, Saša Z.; Stošović-Kalezić, Ivana

(Srpsko lekarsko društvo, Beograd, 2017)

TY  - JOUR
AU  - Martinović, Brankica
AU  - Ivanović, Mirjana
AU  - Cvetković, Andrijana
AU  - Todić, Jelena
AU  - Milojković, Zoraida
AU  - Pavlović, Jasna
AU  - Tabaković, Saša Z.
AU  - Stošović-Kalezić, Ivana
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2263
AB  - Introduction/Objective: Molar-incisor hypomnineralization (MIH) is relatively common developmental anomaly characterized by hypomineralized enamel defects in the first permanent molars and incisors. The aim of this study was to determine the prevalence of hypomineralization of the first permanent molars and incisors in children aged eight and 10 years who live in the northern part of Kosovo and Metohija. Methods: The study included 712 respondents, 289 of whom aged eight (40.6%) and 423 of whom aged 10 years (59.4%). Criteria according to Weerheijm were used for diagnosis of hypomineralization and the severity of changes was determined. Results: The frequency of hypomineralized changes in the first permanent molars and incisors of the examined children in this area was 12.2%. It was lower in children aged eight years (10.7%) compared to those aged 10 (13.2%). Demarcated enamel opacity was more common in younger children, whereas both atypical restoration and tooth extraction due to hypomineralization were more common in older children. Mild form is more common in children aged eight years, whereas both severe form and severe form with extracted teeth are more common in children aged 10 years. The results indicate that the first permanent molars were most commonly affected by MIH changes. Conclusion: The percentage of the respondents with MIH changes in the northern part of Kosovo and Metohija, which is 12.2%, is not negligible and points to the necessity of early diagnosis in order to prevent and reduce the complications of the condition by timely prevention and treatment.
AB  - Uvod/Cilj: Hipomineralizacija kutnjaka i sekutića (HKS) relativno je česta razvojna anomalija koja se karakteriše pojavom hipomineralizovanih defekata gleđi na prvim stalnim kutnjacima i sekutićima. Cilj ovog rada bio je da se ispita učestalost hipomineralizacije na prvim stalnim kutnjacima i sekutićima kod dece uzrasta osam i deset godina na području severnog dela Kosova i Metohije. Metode: U istraživanju je bilo uključeno 712 ispitanika – 289 uzrasta osam godina (40,6%) i 423 (59,4%) uzrasta deset godina. Za dijagnozu oboljenja primenjeni su kriterijumi po Weerhejim-u i određen je stepen izraženosti promena. Rezultati: Učestalost hipomineralizovanih promena na prvim stalnim kutnjacima i sekutićima kod ispitivane dece na ovom području iznosio je 12,2%. Kod dece od osam godina učestalost ovih promena je manja (10,7%) u odnosu na ispitanike od deset godina (13,2%). Ograničena zamućenost gleđi bila je učestalija kod dece mlađeg uzrasta, dok je kod dece starijeg uzrasta učestalija atipična restauracija i ekstrakcija zuba kao posledica hipomineralizacije. Blaga forma je učestalija kod dece od osam godina, dok je kod dece od deset godina učestalija teška forma, kao i teška forma koja uključuje i ekstrahirane zube. Rezultati pokazuju da su prvi stalni kutnjaci najčešće zahvaćeni hipomineralizovanim promena. Zaključak: Procenat od 12,2% ispitanika sa promenama HKS na području severnog dela Kosova i Metohije nije zanemarljiv. Ovakvo stanje ukazuje na neophodnost rane dijagnostike da bi se blagovremenom prevencijom i terapijom sprečile i ublažile komplikacije ovog oboljenja.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Prevalence, characteristics and severity of hypomineralization of the first permanent molars and incisors in children from the northern part of Kosovo and Metohija
T1  - Učestalost, karakteristike i stepen izraženosti hipomineralizacije na prvim stalnim kutnjacima i sekutićima kod dece koja žive na području severnog dela Kosova i Metohije
VL  - 145
IS  - 7-8
SP  - 364
EP  - 369
DO  - 10.2298/SARH160614056M
ER  - 
@article{
author = "Martinović, Brankica and Ivanović, Mirjana and Cvetković, Andrijana and Todić, Jelena and Milojković, Zoraida and Pavlović, Jasna and Tabaković, Saša Z. and Stošović-Kalezić, Ivana",
year = "2017",
abstract = "Introduction/Objective: Molar-incisor hypomnineralization (MIH) is relatively common developmental anomaly characterized by hypomineralized enamel defects in the first permanent molars and incisors. The aim of this study was to determine the prevalence of hypomineralization of the first permanent molars and incisors in children aged eight and 10 years who live in the northern part of Kosovo and Metohija. Methods: The study included 712 respondents, 289 of whom aged eight (40.6%) and 423 of whom aged 10 years (59.4%). Criteria according to Weerheijm were used for diagnosis of hypomineralization and the severity of changes was determined. Results: The frequency of hypomineralized changes in the first permanent molars and incisors of the examined children in this area was 12.2%. It was lower in children aged eight years (10.7%) compared to those aged 10 (13.2%). Demarcated enamel opacity was more common in younger children, whereas both atypical restoration and tooth extraction due to hypomineralization were more common in older children. Mild form is more common in children aged eight years, whereas both severe form and severe form with extracted teeth are more common in children aged 10 years. The results indicate that the first permanent molars were most commonly affected by MIH changes. Conclusion: The percentage of the respondents with MIH changes in the northern part of Kosovo and Metohija, which is 12.2%, is not negligible and points to the necessity of early diagnosis in order to prevent and reduce the complications of the condition by timely prevention and treatment., Uvod/Cilj: Hipomineralizacija kutnjaka i sekutića (HKS) relativno je česta razvojna anomalija koja se karakteriše pojavom hipomineralizovanih defekata gleđi na prvim stalnim kutnjacima i sekutićima. Cilj ovog rada bio je da se ispita učestalost hipomineralizacije na prvim stalnim kutnjacima i sekutićima kod dece uzrasta osam i deset godina na području severnog dela Kosova i Metohije. Metode: U istraživanju je bilo uključeno 712 ispitanika – 289 uzrasta osam godina (40,6%) i 423 (59,4%) uzrasta deset godina. Za dijagnozu oboljenja primenjeni su kriterijumi po Weerhejim-u i određen je stepen izraženosti promena. Rezultati: Učestalost hipomineralizovanih promena na prvim stalnim kutnjacima i sekutićima kod ispitivane dece na ovom području iznosio je 12,2%. Kod dece od osam godina učestalost ovih promena je manja (10,7%) u odnosu na ispitanike od deset godina (13,2%). Ograničena zamućenost gleđi bila je učestalija kod dece mlađeg uzrasta, dok je kod dece starijeg uzrasta učestalija atipična restauracija i ekstrakcija zuba kao posledica hipomineralizacije. Blaga forma je učestalija kod dece od osam godina, dok je kod dece od deset godina učestalija teška forma, kao i teška forma koja uključuje i ekstrahirane zube. Rezultati pokazuju da su prvi stalni kutnjaci najčešće zahvaćeni hipomineralizovanim promena. Zaključak: Procenat od 12,2% ispitanika sa promenama HKS na području severnog dela Kosova i Metohije nije zanemarljiv. Ovakvo stanje ukazuje na neophodnost rane dijagnostike da bi se blagovremenom prevencijom i terapijom sprečile i ublažile komplikacije ovog oboljenja.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Prevalence, characteristics and severity of hypomineralization of the first permanent molars and incisors in children from the northern part of Kosovo and Metohija, Učestalost, karakteristike i stepen izraženosti hipomineralizacije na prvim stalnim kutnjacima i sekutićima kod dece koja žive na području severnog dela Kosova i Metohije",
volume = "145",
number = "7-8",
pages = "364-369",
doi = "10.2298/SARH160614056M"
}
Martinović, B., Ivanović, M., Cvetković, A., Todić, J., Milojković, Z., Pavlović, J., Tabaković, S. Z.,& Stošović-Kalezić, I.. (2017). Prevalence, characteristics and severity of hypomineralization of the first permanent molars and incisors in children from the northern part of Kosovo and Metohija. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 145(7-8), 364-369.
https://doi.org/10.2298/SARH160614056M
Martinović B, Ivanović M, Cvetković A, Todić J, Milojković Z, Pavlović J, Tabaković SZ, Stošović-Kalezić I. Prevalence, characteristics and severity of hypomineralization of the first permanent molars and incisors in children from the northern part of Kosovo and Metohija. in Srpski arhiv za celokupno lekarstvo. 2017;145(7-8):364-369.
doi:10.2298/SARH160614056M .
Martinović, Brankica, Ivanović, Mirjana, Cvetković, Andrijana, Todić, Jelena, Milojković, Zoraida, Pavlović, Jasna, Tabaković, Saša Z., Stošović-Kalezić, Ivana, "Prevalence, characteristics and severity of hypomineralization of the first permanent molars and incisors in children from the northern part of Kosovo and Metohija" in Srpski arhiv za celokupno lekarstvo, 145, no. 7-8 (2017):364-369,
https://doi.org/10.2298/SARH160614056M . .
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Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor

Tabaković, Saša Z.; Konstantinović, Vitomir; Radosavljević, Radivoje; Movrin, Dejan; Hadžistević, Miodrag; Hatab, Nur

(Lippincott Williams & Wilkins, Philadelphia, 2015)

TY  - JOUR
AU  - Tabaković, Saša Z.
AU  - Konstantinović, Vitomir
AU  - Radosavljević, Radivoje
AU  - Movrin, Dejan
AU  - Hadžistević, Miodrag
AU  - Hatab, Nur
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2005
AB  - Introduction: Traumatology of the maxillofacial region represents a wide range of different types of facial skeletal injuries and encompasses numerous treatment methods. Application of computer-aided design (CAD) in combination with rapid prototyping (RP) technologies and three-dimensional computed tomography techniques facilitates surgical therapy planning for efficient treatment. Objective: The purpose of this study is to determine the efficiency of individually designed implants of poly-DL-lactide (PDLLA) in the reconstruction of blowout fractures of the orbital floor. Methods: In the course of a surgical treatment, individually designed implants manufactured by CAD/RP technologies were used. Preoperative analysis and postoperative monitoring were conducted to evaluate the successfulness of orbital floor reconstruction using customized PDLLA implants, based on: presence of diplopia, paresthesia of infraorbital nerve, and presence of enophthalmos. Results: In 6 of the 10 patients, diplopia completely disappeared immediately after surgical procedure. Diplopia gradually disappeared after 1 month in 3 patients, whereas in 1, it remained even after 6 months. In 7 patients, paresthesia disappeared within a month after surgery and in 3 patients within 2 months. Postoperative average Orbital volume (OV) of the injured side (13.333 +/- 3.177) was significantly reduced in comparison with preoperative OV (15.847 +/- 3.361) after reconstruction of the orbital floor with customized PDLLA implant (P  lt  0.001). Thus, average OV of corrected orbit was not different compared with the OV of the uninjured orbit (P = 0.981). Conclusions: Reconstruction of blowout fractures of the orbital floor by an individually designed PDLLA implant combined with virtual preoperative modeling allows easier preoperative preparation and yields satisfactory functional and esthetic outcomes.
PB  - Lippincott Williams & Wilkins, Philadelphia
T2  - Journal of Craniofacial Surgery
T1  - Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor
VL  - 26
IS  - 5
SP  - 1558
EP  - 1563
DO  - 10.1097/SCS.0000000000001883
ER  - 
@article{
author = "Tabaković, Saša Z. and Konstantinović, Vitomir and Radosavljević, Radivoje and Movrin, Dejan and Hadžistević, Miodrag and Hatab, Nur",
year = "2015",
abstract = "Introduction: Traumatology of the maxillofacial region represents a wide range of different types of facial skeletal injuries and encompasses numerous treatment methods. Application of computer-aided design (CAD) in combination with rapid prototyping (RP) technologies and three-dimensional computed tomography techniques facilitates surgical therapy planning for efficient treatment. Objective: The purpose of this study is to determine the efficiency of individually designed implants of poly-DL-lactide (PDLLA) in the reconstruction of blowout fractures of the orbital floor. Methods: In the course of a surgical treatment, individually designed implants manufactured by CAD/RP technologies were used. Preoperative analysis and postoperative monitoring were conducted to evaluate the successfulness of orbital floor reconstruction using customized PDLLA implants, based on: presence of diplopia, paresthesia of infraorbital nerve, and presence of enophthalmos. Results: In 6 of the 10 patients, diplopia completely disappeared immediately after surgical procedure. Diplopia gradually disappeared after 1 month in 3 patients, whereas in 1, it remained even after 6 months. In 7 patients, paresthesia disappeared within a month after surgery and in 3 patients within 2 months. Postoperative average Orbital volume (OV) of the injured side (13.333 +/- 3.177) was significantly reduced in comparison with preoperative OV (15.847 +/- 3.361) after reconstruction of the orbital floor with customized PDLLA implant (P  lt  0.001). Thus, average OV of corrected orbit was not different compared with the OV of the uninjured orbit (P = 0.981). Conclusions: Reconstruction of blowout fractures of the orbital floor by an individually designed PDLLA implant combined with virtual preoperative modeling allows easier preoperative preparation and yields satisfactory functional and esthetic outcomes.",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "Journal of Craniofacial Surgery",
title = "Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor",
volume = "26",
number = "5",
pages = "1558-1563",
doi = "10.1097/SCS.0000000000001883"
}
Tabaković, S. Z., Konstantinović, V., Radosavljević, R., Movrin, D., Hadžistević, M.,& Hatab, N.. (2015). Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor. in Journal of Craniofacial Surgery
Lippincott Williams & Wilkins, Philadelphia., 26(5), 1558-1563.
https://doi.org/10.1097/SCS.0000000000001883
Tabaković SZ, Konstantinović V, Radosavljević R, Movrin D, Hadžistević M, Hatab N. Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor. in Journal of Craniofacial Surgery. 2015;26(5):1558-1563.
doi:10.1097/SCS.0000000000001883 .
Tabaković, Saša Z., Konstantinović, Vitomir, Radosavljević, Radivoje, Movrin, Dejan, Hadžistević, Miodrag, Hatab, Nur, "Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor" in Journal of Craniofacial Surgery, 26, no. 5 (2015):1558-1563,
https://doi.org/10.1097/SCS.0000000000001883 . .
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21
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Reconstruction of the orbital floor with individually designed resorptive materials polydioxanone lactide (pdlla) and symphyseal bone graft mandible

Tabaković, Saša Z.

(Univerzitet u Beogradu, Stomatološki fakultet, 2015)

TY  - THES
AU  - Tabaković, Saša Z.
PY  - 2015
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=2792
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:10963/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=47660815
UR  - http://nardus.mpn.gov.rs/123456789/5180
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/979
AB  - An isolated fracture of the orbital floor is a rare trauma of the craniofacial region. This type of fracture demands a specific clinical care due to the defect presence, unlike other facial fractures. Fracture may lead to deformity of the face, and may affect the function of the nervous system and sight. Medical misdiagnosis and inadequate treatment can have serious consequences that must be prevented. However, despite the surgical treatment, fracture of the orbital floor is still connected with the risk of the emergence of post-operative complications such as diplopia and enophthalmos. The treatment is rather complex, and rehabilitation of the patients is quite a demanding one and mostly depends on the type of material that is used in the treatment. Defect of the orbital floor requires reconstruction in order to establish anatomical function of the injured skeleton. Reconstruction requires implantation of autologous tissue or biocompatible implant that replaces the missing tissue, usually bone. For osseous defects in maxillofacial region autotransplants can be used. However, the problem is that the bony autotransplants are limited in size and there is also a possiblity of complications in the donor region. Besides the bony autotransplants, the use of resorptive and non resorptive synthetic biomaterials has become more frequent , which is in the form of implants used to replace and repair living tissue or organs for both health and aesthetic reasons. The possibility of implant modelling according to defect shape and size, elimination of the second operating field (donor regions) and satisfying functional and aesthetic results make these materials even more suitable for orbital floor reconstruction. Importance of virtual modelling and rapid prototyping over the last few years has been pointed out. Rapid prototyping (RP – rapid prototyping) is one of the technologies that have been growing fast at the moment...
AB  - Izolovani prelom poda orbite spada u retke povrede kraniofacijalne regije. Zbog prisustva defekta, ova vrsta preloma zaslužuje specifičnu kliničku pažnju za razliku od ostalih preloma skeleta lica. Prelom može dovesti do deformiteta lica, a može uticati na funkciju vida i nervnog sistema. Propusti u dijagnostikovanju preloma ili u tretmanu, mogu da dovedu do ozbiljnih posledica koje se moraju sprečiti. Međutim, i pored hirurškog tertmana, prelom poda orbite povezan je sa rizikom od nastajanja postoperativnih komplikacija kao što su diplopija i enoftalmus. Lečenje je dosta kompleksno, a rehabilitacija pacijenata je prilično zahtevna i u mnogome zavisi od vrste materijala koji se primenjuje u lečenju. Defekt poda orbite zahteva rekonstrukciju kako bi se uspostavila anatomaska funkcija povređenog dela skeleta. Rekonstrukcija zahteva implantaciju autolognog tkiva ili biokompatibilnog implantata kojim se zamenjuje nedostajuće tkivo, najčešće kost. Za koštane defekte u maksilofacijalnoj regiji mogu se primeniti koštani autotransplantati. Međutim, problem je što su koštani autotransplantati limitirani veličinom, a pored toga moguće su i komplikacije u donorskoj regiji. Pored koštanih transplantata sve je češća primena neresorptivnih i resorptivnih veštačkih biomaterijala koji se u vidu implantata koriste za zamenu i reparaciju živog tkiva ili organa kako iz zdravstvenih tako i iz estetskih razloga. Mogućnost modelovanja implantata shodno obliku i veličini defekta, eliminacija drugog operativnog polja (donorske regije) i zadovoljavajući funkcionalni i estetski rezultati, ove materijale čine još pogodnijim za rekonstrukciju poda orbite. U poslednijih nekoliko godina ukazano je na značaj virtuelnog modeliranja i brze izrade prototipova. Brza izrada prototipova (engl. rapid prototyping – RP) jedna je od tehnologija koje trenutno najbrže napreduje. Pokazalo se da su kranijalna i maksilofacijalna regija vrlo pogodne za primenu ove vrste tehnologije...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Reconstruction of the orbital floor with individually designed resorptive materials polydioxanone lactide (pdlla) and symphyseal bone graft mandible
T1  - Rekonstrukcija poda orbite individualno oblikovanim resorptivnim materijalom polidioksan laktidom (PDLLA) i simfiznim graftom mandibule
UR  - https://hdl.handle.net/21.15107/rcub_nardus_5180
ER  - 
@phdthesis{
author = "Tabaković, Saša Z.",
year = "2015",
abstract = "An isolated fracture of the orbital floor is a rare trauma of the craniofacial region. This type of fracture demands a specific clinical care due to the defect presence, unlike other facial fractures. Fracture may lead to deformity of the face, and may affect the function of the nervous system and sight. Medical misdiagnosis and inadequate treatment can have serious consequences that must be prevented. However, despite the surgical treatment, fracture of the orbital floor is still connected with the risk of the emergence of post-operative complications such as diplopia and enophthalmos. The treatment is rather complex, and rehabilitation of the patients is quite a demanding one and mostly depends on the type of material that is used in the treatment. Defect of the orbital floor requires reconstruction in order to establish anatomical function of the injured skeleton. Reconstruction requires implantation of autologous tissue or biocompatible implant that replaces the missing tissue, usually bone. For osseous defects in maxillofacial region autotransplants can be used. However, the problem is that the bony autotransplants are limited in size and there is also a possiblity of complications in the donor region. Besides the bony autotransplants, the use of resorptive and non resorptive synthetic biomaterials has become more frequent , which is in the form of implants used to replace and repair living tissue or organs for both health and aesthetic reasons. The possibility of implant modelling according to defect shape and size, elimination of the second operating field (donor regions) and satisfying functional and aesthetic results make these materials even more suitable for orbital floor reconstruction. Importance of virtual modelling and rapid prototyping over the last few years has been pointed out. Rapid prototyping (RP – rapid prototyping) is one of the technologies that have been growing fast at the moment..., Izolovani prelom poda orbite spada u retke povrede kraniofacijalne regije. Zbog prisustva defekta, ova vrsta preloma zaslužuje specifičnu kliničku pažnju za razliku od ostalih preloma skeleta lica. Prelom može dovesti do deformiteta lica, a može uticati na funkciju vida i nervnog sistema. Propusti u dijagnostikovanju preloma ili u tretmanu, mogu da dovedu do ozbiljnih posledica koje se moraju sprečiti. Međutim, i pored hirurškog tertmana, prelom poda orbite povezan je sa rizikom od nastajanja postoperativnih komplikacija kao što su diplopija i enoftalmus. Lečenje je dosta kompleksno, a rehabilitacija pacijenata je prilično zahtevna i u mnogome zavisi od vrste materijala koji se primenjuje u lečenju. Defekt poda orbite zahteva rekonstrukciju kako bi se uspostavila anatomaska funkcija povređenog dela skeleta. Rekonstrukcija zahteva implantaciju autolognog tkiva ili biokompatibilnog implantata kojim se zamenjuje nedostajuće tkivo, najčešće kost. Za koštane defekte u maksilofacijalnoj regiji mogu se primeniti koštani autotransplantati. Međutim, problem je što su koštani autotransplantati limitirani veličinom, a pored toga moguće su i komplikacije u donorskoj regiji. Pored koštanih transplantata sve je češća primena neresorptivnih i resorptivnih veštačkih biomaterijala koji se u vidu implantata koriste za zamenu i reparaciju živog tkiva ili organa kako iz zdravstvenih tako i iz estetskih razloga. Mogućnost modelovanja implantata shodno obliku i veličini defekta, eliminacija drugog operativnog polja (donorske regije) i zadovoljavajući funkcionalni i estetski rezultati, ove materijale čine još pogodnijim za rekonstrukciju poda orbite. U poslednijih nekoliko godina ukazano je na značaj virtuelnog modeliranja i brze izrade prototipova. Brza izrada prototipova (engl. rapid prototyping – RP) jedna je od tehnologija koje trenutno najbrže napreduje. Pokazalo se da su kranijalna i maksilofacijalna regija vrlo pogodne za primenu ove vrste tehnologije...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Reconstruction of the orbital floor with individually designed resorptive materials polydioxanone lactide (pdlla) and symphyseal bone graft mandible, Rekonstrukcija poda orbite individualno oblikovanim resorptivnim materijalom polidioksan laktidom (PDLLA) i simfiznim graftom mandibule",
url = "https://hdl.handle.net/21.15107/rcub_nardus_5180"
}
Tabaković, S. Z.. (2015). Reconstruction of the orbital floor with individually designed resorptive materials polydioxanone lactide (pdlla) and symphyseal bone graft mandible. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_5180
Tabaković SZ. Reconstruction of the orbital floor with individually designed resorptive materials polydioxanone lactide (pdlla) and symphyseal bone graft mandible. 2015;.
https://hdl.handle.net/21.15107/rcub_nardus_5180 .
Tabaković, Saša Z., "Reconstruction of the orbital floor with individually designed resorptive materials polydioxanone lactide (pdlla) and symphyseal bone graft mandible" (2015),
https://hdl.handle.net/21.15107/rcub_nardus_5180 .

Incidence and clinical relevance of t(11;19) translocation in salivary gland mucoepidermoid carcinoma

Ilic-Dimitrijević, Ivana; Loening, Thomas; Falk, Marcus; Konstantinović, Vitomir; Vukadinović, Miroslav; Tepavčević, Zvezdana; Tabaković, Saša Z.; Pejčić, Nataša; Miličić, Biljana; Milašin, Jelena

(Društvo genetičara Srbije, Beograd, 2014)

TY  - JOUR
AU  - Ilic-Dimitrijević, Ivana
AU  - Loening, Thomas
AU  - Falk, Marcus
AU  - Konstantinović, Vitomir
AU  - Vukadinović, Miroslav
AU  - Tepavčević, Zvezdana
AU  - Tabaković, Saša Z.
AU  - Pejčić, Nataša
AU  - Miličić, Biljana
AU  - Milašin, Jelena
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1926
AB  - Mucoepidermoid carcinoma (MEC) harbors a recurring t(11;19) translocation with an associated novel fusion oncogene-MECT1-MAML2. The CRTC1-MAML2oncogene disrupts normal cell-cycle and differentiation, contributing to tumor development. The objectives of this study were to establish the incidence of CRTC1-MAML2 fusion in Serbian patients and estimate its relevance as a genetic marker of MEC behavior. In this retrospective study, 20 cases of MEC of salivary glands were tested for the presence of CRTC1-MAML2 fusion using reverse transcriptase-polymerase chain reaction. Clinicopathological parameters and survival data were examined in relation to fusion status. The CRTC1-MAML2 fusion was detected in 40% of MECs and its presence was associated exclusively with low-intermediate grade tumor histology (P = 0.02) and favorable clinical outcome, with 100 % overall survival rate (P=0.046). The study has shown that the presence of the CRTC1-MAML2 fusion can serve as an additional diagnostic and prognostic marker for mucoepidermoid carcinomas.
PB  - Društvo genetičara Srbije, Beograd
T2  - Genetika - Belgrade
T1  - Incidence and clinical relevance of t(11;19) translocation in salivary gland mucoepidermoid carcinoma
VL  - 46
IS  - 2
SP  - 601
EP  - 610
DO  - 10.2298/GENSR1402601D
ER  - 
@article{
author = "Ilic-Dimitrijević, Ivana and Loening, Thomas and Falk, Marcus and Konstantinović, Vitomir and Vukadinović, Miroslav and Tepavčević, Zvezdana and Tabaković, Saša Z. and Pejčić, Nataša and Miličić, Biljana and Milašin, Jelena",
year = "2014",
abstract = "Mucoepidermoid carcinoma (MEC) harbors a recurring t(11;19) translocation with an associated novel fusion oncogene-MECT1-MAML2. The CRTC1-MAML2oncogene disrupts normal cell-cycle and differentiation, contributing to tumor development. The objectives of this study were to establish the incidence of CRTC1-MAML2 fusion in Serbian patients and estimate its relevance as a genetic marker of MEC behavior. In this retrospective study, 20 cases of MEC of salivary glands were tested for the presence of CRTC1-MAML2 fusion using reverse transcriptase-polymerase chain reaction. Clinicopathological parameters and survival data were examined in relation to fusion status. The CRTC1-MAML2 fusion was detected in 40% of MECs and its presence was associated exclusively with low-intermediate grade tumor histology (P = 0.02) and favorable clinical outcome, with 100 % overall survival rate (P=0.046). The study has shown that the presence of the CRTC1-MAML2 fusion can serve as an additional diagnostic and prognostic marker for mucoepidermoid carcinomas.",
publisher = "Društvo genetičara Srbije, Beograd",
journal = "Genetika - Belgrade",
title = "Incidence and clinical relevance of t(11;19) translocation in salivary gland mucoepidermoid carcinoma",
volume = "46",
number = "2",
pages = "601-610",
doi = "10.2298/GENSR1402601D"
}
Ilic-Dimitrijević, I., Loening, T., Falk, M., Konstantinović, V., Vukadinović, M., Tepavčević, Z., Tabaković, S. Z., Pejčić, N., Miličić, B.,& Milašin, J.. (2014). Incidence and clinical relevance of t(11;19) translocation in salivary gland mucoepidermoid carcinoma. in Genetika - Belgrade
Društvo genetičara Srbije, Beograd., 46(2), 601-610.
https://doi.org/10.2298/GENSR1402601D
Ilic-Dimitrijević I, Loening T, Falk M, Konstantinović V, Vukadinović M, Tepavčević Z, Tabaković SZ, Pejčić N, Miličić B, Milašin J. Incidence and clinical relevance of t(11;19) translocation in salivary gland mucoepidermoid carcinoma. in Genetika - Belgrade. 2014;46(2):601-610.
doi:10.2298/GENSR1402601D .
Ilic-Dimitrijević, Ivana, Loening, Thomas, Falk, Marcus, Konstantinović, Vitomir, Vukadinović, Miroslav, Tepavčević, Zvezdana, Tabaković, Saša Z., Pejčić, Nataša, Miličić, Biljana, Milašin, Jelena, "Incidence and clinical relevance of t(11;19) translocation in salivary gland mucoepidermoid carcinoma" in Genetika - Belgrade, 46, no. 2 (2014):601-610,
https://doi.org/10.2298/GENSR1402601D . .
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