TY  - JOUR
AU  - Velicković, Jelena
AU  - Palibrk, Ivan
AU  - Miličić, Biljana
AU  - Velicković, Dejan
AU  - Jovanović, Bojan
AU  - Rakić, Goran
AU  - Petrović, Milorad
AU  - Bumbaširević, Vesna
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2461
AB  - Lactate levels are widely used as an indicator of outcome in critically ill patients. We investigated the prognostic value of postoperative lactate levels for postoperative complications (POCs), mortality and length of hospital stay after elective major abdominal surgery. A total of 195 patients were prospectively evaluated. Lactate levels were assessed on admission to the intensive care unit (ICU) [L-0], at 4 hours (L-4), 12 hours (L-12), and 24 hours (L-24) after the operation. Demographic and perioperative clinical data were collected. Patients were monitored for complications until discharge or death. Receiver operating characteristic (ROC) curves were used to determine the predictive value of lactate levels for postoperative outcomes. The best cut-off lactate values were calculated to differentiate between patients with and without complications, and outcomes in patients with lactate levels above and below the cut-off thresholds were compared. Univariate and multivariate analyses were used to identify variables associated with POCs and mortality. Seventy-six patients developed 184 complications (18 deaths), while 119 had no complications. Serum lactate levels were higher in patients with complications at all time points compared to those without complications (p  lt  0.001). L-12 had the highest predictive value for complications (AUROC(12) = 0.787; 95% CI: 0.719-0.854; p  lt  0.001) and mortality (AUROC(12) = 0.872; 95% CI: 0.794-0.950;p  lt  0.00l). The best L-12 cut-off value for complications and mortality was 1.35 mmol/l and 1.85 mmol/l, respectively. Multivariate analysis revealed that L-1(2) >= 1.35 mml/l was an independent predictor of postoperative morbidity (OR 2.58; 95% CI 1.27-5.24,p = 0.001) . L-24 was predictive of POCs after major abdominal surgery. L-12 had the best power to discriminate between patients with and without POCs and was associated with a longer hospital stay.
PB  - Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa
T2  - Bosnian Journal of Basic Medical Sciences
T1  - The association of early postoperative lactate levels with morbidity after elective major abdominal surgery
VL  - 19
IS  - 1
SP  - 72
EP  - 80
DO  - 10.17305/bjbms.2018.3186
ER  - 

@article{
author = "Velicković, Jelena and Palibrk, Ivan and Miličić, Biljana and Velicković, Dejan and Jovanović, Bojan and Rakić, Goran and Petrović, Milorad and Bumbaširević, Vesna",
year = "2019",
abstract = "Lactate levels are widely used as an indicator of outcome in critically ill patients. We investigated the prognostic value of postoperative lactate levels for postoperative complications (POCs), mortality and length of hospital stay after elective major abdominal surgery. A total of 195 patients were prospectively evaluated. Lactate levels were assessed on admission to the intensive care unit (ICU) [L-0], at 4 hours (L-4), 12 hours (L-12), and 24 hours (L-24) after the operation. Demographic and perioperative clinical data were collected. Patients were monitored for complications until discharge or death. Receiver operating characteristic (ROC) curves were used to determine the predictive value of lactate levels for postoperative outcomes. The best cut-off lactate values were calculated to differentiate between patients with and without complications, and outcomes in patients with lactate levels above and below the cut-off thresholds were compared. Univariate and multivariate analyses were used to identify variables associated with POCs and mortality. Seventy-six patients developed 184 complications (18 deaths), while 119 had no complications. Serum lactate levels were higher in patients with complications at all time points compared to those without complications (p  lt  0.001). L-12 had the highest predictive value for complications (AUROC(12) = 0.787; 95% CI: 0.719-0.854; p  lt  0.001) and mortality (AUROC(12) = 0.872; 95% CI: 0.794-0.950;p  lt  0.00l). The best L-12 cut-off value for complications and mortality was 1.35 mmol/l and 1.85 mmol/l, respectively. Multivariate analysis revealed that L-1(2) >= 1.35 mml/l was an independent predictor of postoperative morbidity (OR 2.58; 95% CI 1.27-5.24,p = 0.001) . L-24 was predictive of POCs after major abdominal surgery. L-12 had the best power to discriminate between patients with and without POCs and was associated with a longer hospital stay.",
publisher = "Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa",
journal = "Bosnian Journal of Basic Medical Sciences",
title = "The association of early postoperative lactate levels with morbidity after elective major abdominal surgery",
volume = "19",
number = "1",
pages = "72-80",
doi = "10.17305/bjbms.2018.3186"
}

Velicković, J., Palibrk, I., Miličić, B., Velicković, D., Jovanović, B., Rakić, G., Petrović, M.,& Bumbaširević, V.. (2019). The association of early postoperative lactate levels with morbidity after elective major abdominal surgery. in Bosnian Journal of Basic Medical Sciences
Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa., 19(1), 72-80.
https://doi.org/10.17305/bjbms.2018.3186

Velicković J, Palibrk I, Miličić B, Velicković D, Jovanović B, Rakić G, Petrović M, Bumbaširević V. The association of early postoperative lactate levels with morbidity after elective major abdominal surgery. in Bosnian Journal of Basic Medical Sciences. 2019;19(1):72-80.
doi:10.17305/bjbms.2018.3186 .

Velicković, Jelena, Palibrk, Ivan, Miličić, Biljana, Velicković, Dejan, Jovanović, Bojan, Rakić, Goran, Petrović, Milorad, Bumbaširević, Vesna, "The association of early postoperative lactate levels with morbidity after elective major abdominal surgery" in Bosnian Journal of Basic Medical Sciences, 19, no. 1 (2019):72-80,
https://doi.org/10.17305/bjbms.2018.3186 . .

TY  - JOUR
AU  - Tripković, Slađana
AU  - Pavlović, Aleksandar
AU  - Bumbaširević, Vesna
AU  - Sekulić, Ana
AU  - Miličić, Biljana
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1959
AB  - Introduction In relation to pre-hospital treatment of patients with cardiac arrest (CA) in the field where resuscitation is often started by nonprofessionals, resuscitation in hospital is most commonly performed by well-trained personnel. Objective The aim was to define the factors associated with an improved outcome among patients suffering from the in hospital CA (INCA). Methods The prospective study included a total of 100 patients in the Emergency Center over two-year period. The patterns by the Utstein-Style guidelines recorded the following: age, sex, reason for hospital admission, comorbidity, cause and origin of CA, continuous monitoring, time of arrival of the medical emergency team and time of delivery of the first defibrillation shock (DC). Results Most patients (61%) had cardiac etiology. Return of spontaneous circulation (ROSC) was achieved in 58% of patients. ROSC was more frequently achieved in younger patients (57.69 +/- 11.37), (p lt 0.05), non-surgical patients (76.1%), (p lt 0.01) and in patients who were in continuous monitoring (66.7%) (p lt 0.05).The outcome of CPR was significantly better in patients who received advanced life support (ALS) (76.6%) (p lt 0.01).Time until the delivery of the first DC shock was significantly shorter in patients who achieved ROSC (1.67 +/- 1.13 min), (p lt 0.01). A total of 5% of IHCA patients survived to hospital discharge. Conclusion In our study, the outcome of CPR was better in patients who were younger and with non-surgical diseases, which are prognostic factors that we cannot control. Factors associated with better outcome of IHCA patients were: continuous monitoring, shorter time until the delivery of the first DC and ALS. This means that better education of medical staff, better organization and up-to-dated technical equipment are needed.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Outcome among Patients Suffering from In-Hospital Cardiac Arrest
VL  - 142
IS  - 3-4
SP  - 170
EP  - 177
DO  - 10.2298/SARH1404170T
ER  - 

@article{
author = "Tripković, Slađana and Pavlović, Aleksandar and Bumbaširević, Vesna and Sekulić, Ana and Miličić, Biljana",
year = "2014",
abstract = "Introduction In relation to pre-hospital treatment of patients with cardiac arrest (CA) in the field where resuscitation is often started by nonprofessionals, resuscitation in hospital is most commonly performed by well-trained personnel. Objective The aim was to define the factors associated with an improved outcome among patients suffering from the in hospital CA (INCA). Methods The prospective study included a total of 100 patients in the Emergency Center over two-year period. The patterns by the Utstein-Style guidelines recorded the following: age, sex, reason for hospital admission, comorbidity, cause and origin of CA, continuous monitoring, time of arrival of the medical emergency team and time of delivery of the first defibrillation shock (DC). Results Most patients (61%) had cardiac etiology. Return of spontaneous circulation (ROSC) was achieved in 58% of patients. ROSC was more frequently achieved in younger patients (57.69 +/- 11.37), (p lt 0.05), non-surgical patients (76.1%), (p lt 0.01) and in patients who were in continuous monitoring (66.7%) (p lt 0.05).The outcome of CPR was significantly better in patients who received advanced life support (ALS) (76.6%) (p lt 0.01).Time until the delivery of the first DC shock was significantly shorter in patients who achieved ROSC (1.67 +/- 1.13 min), (p lt 0.01). A total of 5% of IHCA patients survived to hospital discharge. Conclusion In our study, the outcome of CPR was better in patients who were younger and with non-surgical diseases, which are prognostic factors that we cannot control. Factors associated with better outcome of IHCA patients were: continuous monitoring, shorter time until the delivery of the first DC and ALS. This means that better education of medical staff, better organization and up-to-dated technical equipment are needed.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Outcome among Patients Suffering from In-Hospital Cardiac Arrest",
volume = "142",
number = "3-4",
pages = "170-177",
doi = "10.2298/SARH1404170T"
}

Tripković, S., Pavlović, A., Bumbaširević, V., Sekulić, A.,& Miličić, B.. (2014). Outcome among Patients Suffering from In-Hospital Cardiac Arrest. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 142(3-4), 170-177.
https://doi.org/10.2298/SARH1404170T

Tripković S, Pavlović A, Bumbaširević V, Sekulić A, Miličić B. Outcome among Patients Suffering from In-Hospital Cardiac Arrest. in Srpski arhiv za celokupno lekarstvo. 2014;142(3-4):170-177.
doi:10.2298/SARH1404170T .

Tripković, Slađana, Pavlović, Aleksandar, Bumbaširević, Vesna, Sekulić, Ana, Miličić, Biljana, "Outcome among Patients Suffering from In-Hospital Cardiac Arrest" in Srpski arhiv za celokupno lekarstvo, 142, no. 3-4 (2014):170-177,
https://doi.org/10.2298/SARH1404170T . .

TY  - JOUR
AU  - Palibrk, Ivan
AU  - Miličić, Biljana
AU  - Stojiljković, Ljuba
AU  - Manojlović, Nebojša
AU  - Dugalić, Vladimir
AU  - Bumbaširević, Vesna
AU  - Kalezić, Nevena
AU  - Žuvela, Marinko
AU  - Milicević, Miroslav
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1736
AB  - Background/Aims: Liver resection is the gold standard in managing patients with metastatic or primary liver cancer. The aim of our study was to compare the traditional clamp-crushing technique to the radiofrequency-assisted liver resection technique in terms of postoperative liver function. Methodology: Liver function was evaluated preoperatively and on postoperative days 3 and 7. Liver synthetic function parameters (serum albumin level, prothrombin time and international normalized ratio), markers of hepatic injury and necrosis (serum alanine aminotransferase, aspartate aminotransferase and total bilirubin level) and microsomal activity (quantitative lidocaine test) were compared. Results: Forty three patients completed the study (14 had clamp-crushing and 29 had radiofrequency assisted liver resection). The groups did not differ in demographic characteristics, pre-operative liver function, operative time and perioperative transfusion rate. In postoperative period, there were similar changes in monitored parameters in both groups except albumin levels, that were higher in radiofrequency-assisted liver resection group (p=0.047). Conclusions: Both, traditional clamp-crushing technique and radiofrequency assisted liver resection technique, result in similar postoperative changes of most monitored liver function parameters.
PB  - H G E Update Medical Publishing S A, Athens
T2  - Hepato-Gastroenterology
T1  - Clamp-Crushing vs. Radiofrequency-Assisted Liver Resection: Changes in Liver Function Tests
VL  - 59
IS  - 115
SP  - 800
EP  - 804
DO  - 10.5754/hge11539
ER  - 

@article{
author = "Palibrk, Ivan and Miličić, Biljana and Stojiljković, Ljuba and Manojlović, Nebojša and Dugalić, Vladimir and Bumbaširević, Vesna and Kalezić, Nevena and Žuvela, Marinko and Milicević, Miroslav",
year = "2012",
abstract = "Background/Aims: Liver resection is the gold standard in managing patients with metastatic or primary liver cancer. The aim of our study was to compare the traditional clamp-crushing technique to the radiofrequency-assisted liver resection technique in terms of postoperative liver function. Methodology: Liver function was evaluated preoperatively and on postoperative days 3 and 7. Liver synthetic function parameters (serum albumin level, prothrombin time and international normalized ratio), markers of hepatic injury and necrosis (serum alanine aminotransferase, aspartate aminotransferase and total bilirubin level) and microsomal activity (quantitative lidocaine test) were compared. Results: Forty three patients completed the study (14 had clamp-crushing and 29 had radiofrequency assisted liver resection). The groups did not differ in demographic characteristics, pre-operative liver function, operative time and perioperative transfusion rate. In postoperative period, there were similar changes in monitored parameters in both groups except albumin levels, that were higher in radiofrequency-assisted liver resection group (p=0.047). Conclusions: Both, traditional clamp-crushing technique and radiofrequency assisted liver resection technique, result in similar postoperative changes of most monitored liver function parameters.",
publisher = "H G E Update Medical Publishing S A, Athens",
journal = "Hepato-Gastroenterology",
title = "Clamp-Crushing vs. Radiofrequency-Assisted Liver Resection: Changes in Liver Function Tests",
volume = "59",
number = "115",
pages = "800-804",
doi = "10.5754/hge11539"
}

Palibrk, I., Miličić, B., Stojiljković, L., Manojlović, N., Dugalić, V., Bumbaširević, V., Kalezić, N., Žuvela, M.,& Milicević, M.. (2012). Clamp-Crushing vs. Radiofrequency-Assisted Liver Resection: Changes in Liver Function Tests. in Hepato-Gastroenterology
H G E Update Medical Publishing S A, Athens., 59(115), 800-804.
https://doi.org/10.5754/hge11539

Palibrk I, Miličić B, Stojiljković L, Manojlović N, Dugalić V, Bumbaširević V, Kalezić N, Žuvela M, Milicević M. Clamp-Crushing vs. Radiofrequency-Assisted Liver Resection: Changes in Liver Function Tests. in Hepato-Gastroenterology. 2012;59(115):800-804.
doi:10.5754/hge11539 .

Palibrk, Ivan, Miličić, Biljana, Stojiljković, Ljuba, Manojlović, Nebojša, Dugalić, Vladimir, Bumbaširević, Vesna, Kalezić, Nevena, Žuvela, Marinko, Milicević, Miroslav, "Clamp-Crushing vs. Radiofrequency-Assisted Liver Resection: Changes in Liver Function Tests" in Hepato-Gastroenterology, 59, no. 115 (2012):800-804,
https://doi.org/10.5754/hge11539 . .