TY  - JOUR
AU  - Stojanović, Marina
AU  - Kalezić, Nevena
AU  - Miličić, Biljana
AU  - Tosković, Anka R.
AU  - Stevanović, Ksenija
AU  - Antonijević, Vesna
AU  - Lakićević, Mirko
AU  - Bagi, Bojan
AU  - Živaljević, Vladan
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2328
AB  - Introduction/Objective Intraoperative variations in blood pressure and/or cardiac dysrhythmias (IOVBP/CD) represent one of the most common causes of morbidity and mortality in surgical patients. The aim of the study was to determine the incidence and risk factors for IOVBP/CD in thyroid surgery patients with comorbidities. Methods The study included 1,252 euthyroid patients with ASA 2 and ASA 3 status (American Society of Anesthesiologists - physical status classification) who underwent thyroid surgery. The following risk factors were examined: sex, age, body mass index (BMI), ASA status, admission diagnoses, type of operation, duration of surgery, time under general anesthesia, difficult intubation of trachea, and coexisting diseases - hypertension, cardiomyopathy, cardiac arrhythmias, angina pectoris, diabetes mellitus, kidney disease. The following intraoperative events were recorded: hypertension, severe hypertension, hypotension, and cardiac arrhythmias. We used Pearson χ2 square test, univariate, and multivariate logistic regression for statistical analysis. Results The majority of patients were female (86.3%). In 903 (72.1%) patients IOVBP/CD were detected. The most common problem was intraoperative hypertension (61.4%). Eight risk factors for IOVBP/CD were registered by univariate analysis: advanced age, ASA 3 status, BMI > 25 kg/m2, duration of surgery, time under general anesthesia, hypertension, and cardiomyopathy as a coexisting disease. The multivariate regression model identified three independent predictors for IOVBP/CD: age, hypertension, and cardiomyopathy. Conclusion IOVBP/CD are common in thyroid surgery. The most common is intraoperative hypertension. Older age, hypertension, and cardiomyopathy as a coexisting disease are independent risk factors for IOVBP/CD.
AB  - Uvod/Cilj Intraoperativne varijacije krvnog pritiska i/ ili srčane disritmije (IVKP/SD) jedan su od najčešćih uzročnika morbiditeta i mortaliteta hirurških bolesnika. Cilj studije je bio da ispita učestalost i faktore rizika za pojavu IVKP/SD u tireoidnoj hirurgiji kod bolesnika sa komorbiditetima. Metode Ispitivanje je obuhvatilo 1252 eutireoidna bolesnika ASA 2 i ASA 3 statusa podvrgnutih tireoidnoj hirurgiji. Ispitivan je uticaj sledećih faktora rizika: pol, starost, indeks telesne mase (ITM), ASA status, prijemna dijagnoza, tip operacije, trajanje operacije, trajanje anestezije, otežana intubacija traheje, kao i komorbiditeti: hipertenzija, kardiomiopatija, srčane aritmije, angina pektoris, dijabetes melitus, bolesti bubrega. Registrovani su intraoperativno: hipertenzija, hipertenzivna kriza, hipotenzija i srčane aritmije. Korišćen je Pirsonov χ2-test, univarijantna i multivarijantna regresiona analiza za statističku obradu podataka. Rezultati Većinu bolesnika su činile žene (86,3%). IVKP/ SD su registrovani kod 903 (72,1%) bolesnika. Najčešći poremećaj je bila intraoperativna hipertenzija - 61,4%. Univarijantnom analizom je registrovano sedam faktora rizika za pojavu IVKP/SD: godine života, ASA 3 status, ITM > 25 kg/m2, trajanje hirurgije, trajanje anestezije, hipertenzija i kardiomiopatija kao komorbiditet. Multivarijantnom regresionom analizom izdvojila su se tri nezavisna prediktora pojave IVKP/SD: godine starosti, hipertenzija i kardiomiopatija. Zaključak IVKP/SD su česte u tireoidnoj hirurgiji. Najčešća je intraoperativna hipertenzija. Starije životno doba, hipertenzija i kardiomiopatija kao koegzistirajuće bolesti su nezavisni faktori rizika za pojavu IVKP/SD.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery
T1  - Faktori rizika za pojavu intraoperativnih varijacija vrednosti krvnog pritiska i srčanih disritmija tokom tireoidne hirurgije
VL  - 146
IS  - 3-4
SP  - 163
EP  - 168
DO  - 10.2298/SARH170522156S
ER  - 

@article{
author = "Stojanović, Marina and Kalezić, Nevena and Miličić, Biljana and Tosković, Anka R. and Stevanović, Ksenija and Antonijević, Vesna and Lakićević, Mirko and Bagi, Bojan and Živaljević, Vladan",
year = "2018",
abstract = "Introduction/Objective Intraoperative variations in blood pressure and/or cardiac dysrhythmias (IOVBP/CD) represent one of the most common causes of morbidity and mortality in surgical patients. The aim of the study was to determine the incidence and risk factors for IOVBP/CD in thyroid surgery patients with comorbidities. Methods The study included 1,252 euthyroid patients with ASA 2 and ASA 3 status (American Society of Anesthesiologists - physical status classification) who underwent thyroid surgery. The following risk factors were examined: sex, age, body mass index (BMI), ASA status, admission diagnoses, type of operation, duration of surgery, time under general anesthesia, difficult intubation of trachea, and coexisting diseases - hypertension, cardiomyopathy, cardiac arrhythmias, angina pectoris, diabetes mellitus, kidney disease. The following intraoperative events were recorded: hypertension, severe hypertension, hypotension, and cardiac arrhythmias. We used Pearson χ2 square test, univariate, and multivariate logistic regression for statistical analysis. Results The majority of patients were female (86.3%). In 903 (72.1%) patients IOVBP/CD were detected. The most common problem was intraoperative hypertension (61.4%). Eight risk factors for IOVBP/CD were registered by univariate analysis: advanced age, ASA 3 status, BMI > 25 kg/m2, duration of surgery, time under general anesthesia, hypertension, and cardiomyopathy as a coexisting disease. The multivariate regression model identified three independent predictors for IOVBP/CD: age, hypertension, and cardiomyopathy. Conclusion IOVBP/CD are common in thyroid surgery. The most common is intraoperative hypertension. Older age, hypertension, and cardiomyopathy as a coexisting disease are independent risk factors for IOVBP/CD., Uvod/Cilj Intraoperativne varijacije krvnog pritiska i/ ili srčane disritmije (IVKP/SD) jedan su od najčešćih uzročnika morbiditeta i mortaliteta hirurških bolesnika. Cilj studije je bio da ispita učestalost i faktore rizika za pojavu IVKP/SD u tireoidnoj hirurgiji kod bolesnika sa komorbiditetima. Metode Ispitivanje je obuhvatilo 1252 eutireoidna bolesnika ASA 2 i ASA 3 statusa podvrgnutih tireoidnoj hirurgiji. Ispitivan je uticaj sledećih faktora rizika: pol, starost, indeks telesne mase (ITM), ASA status, prijemna dijagnoza, tip operacije, trajanje operacije, trajanje anestezije, otežana intubacija traheje, kao i komorbiditeti: hipertenzija, kardiomiopatija, srčane aritmije, angina pektoris, dijabetes melitus, bolesti bubrega. Registrovani su intraoperativno: hipertenzija, hipertenzivna kriza, hipotenzija i srčane aritmije. Korišćen je Pirsonov χ2-test, univarijantna i multivarijantna regresiona analiza za statističku obradu podataka. Rezultati Većinu bolesnika su činile žene (86,3%). IVKP/ SD su registrovani kod 903 (72,1%) bolesnika. Najčešći poremećaj je bila intraoperativna hipertenzija - 61,4%. Univarijantnom analizom je registrovano sedam faktora rizika za pojavu IVKP/SD: godine života, ASA 3 status, ITM > 25 kg/m2, trajanje hirurgije, trajanje anestezije, hipertenzija i kardiomiopatija kao komorbiditet. Multivarijantnom regresionom analizom izdvojila su se tri nezavisna prediktora pojave IVKP/SD: godine starosti, hipertenzija i kardiomiopatija. Zaključak IVKP/SD su česte u tireoidnoj hirurgiji. Najčešća je intraoperativna hipertenzija. Starije životno doba, hipertenzija i kardiomiopatija kao koegzistirajuće bolesti su nezavisni faktori rizika za pojavu IVKP/SD.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery, Faktori rizika za pojavu intraoperativnih varijacija vrednosti krvnog pritiska i srčanih disritmija tokom tireoidne hirurgije",
volume = "146",
number = "3-4",
pages = "163-168",
doi = "10.2298/SARH170522156S"
}

Stojanović, M., Kalezić, N., Miličić, B., Tosković, A. R., Stevanović, K., Antonijević, V., Lakićević, M., Bagi, B.,& Živaljević, V.. (2018). Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 146(3-4), 163-168.
https://doi.org/10.2298/SARH170522156S

Stojanović M, Kalezić N, Miličić B, Tosković AR, Stevanović K, Antonijević V, Lakićević M, Bagi B, Živaljević V. Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery. in Srpski arhiv za celokupno lekarstvo. 2018;146(3-4):163-168.
doi:10.2298/SARH170522156S .

Stojanović, Marina, Kalezić, Nevena, Miličić, Biljana, Tosković, Anka R., Stevanović, Ksenija, Antonijević, Vesna, Lakićević, Mirko, Bagi, Bojan, Živaljević, Vladan, "Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery" in Srpski arhiv za celokupno lekarstvo, 146, no. 3-4 (2018):163-168,
https://doi.org/10.2298/SARH170522156S . .

TY  - JOUR
AU  - Sabljak, Vera
AU  - Živaljević, Vladan
AU  - Miličić, Biljana
AU  - Paunović, Ivan
AU  - Tosković, Anka R.
AU  - Stevanović, Ksenija
AU  - Taušanović, Katarina
AU  - Marković, Dejan Z.
AU  - Stojanović, Marina
AU  - Lakićević, Mirko
AU  - Jovanović, Milan D.
AU  - Diklić, Aleksandar
AU  - Kalezić, Nevena
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2220
AB  - Objective: To investigate the incidence and identify risk factors for the occurrence of intraoperative hypertension (IOH) during surgery for primary hyperparathyroidism (pHPT). Subjects and Methods: The study included 269 patients surgically treated between January 2008 and January 2012 for pHPT. IOH was defined as an increase in systolic blood pressure >= 20% compared to baseline values which lasted for 15min. The investigated influence were demographic characteristics, surgical risk score related to physical status (based on the American Society of Anesthesiologists [ASA] classification), comorbidities, type and duration of surgery, and duration of anesthesia on IOH occurrence. The investigated factors were obtained from the patients' medical history, anesthesia charts, and the daily practice database. Logistic regression analysis was done to determine the predictors of IOH. Results: Of the 269 patients, 153 (56.9%) had IOH. Based on the univariate analysis, age, body mass index, ASA status, duration of anesthesia, and preoperative hypertension were risk factors for the occurrence of IOH. Multivariate analysis showed that independent predictors of IOH were a history of hypertension (OR = 2.080, 95% CI: 1.102-3.925, p = 0.024) and age (OR = 0.569, 95% CI: 0.360-0.901, p = 0.016). Conclusion: In this study, a high percentage (56%) of the patients developed IOH during surgery for pHPT, which indicates that special attention should be paid to these patients, especially to the high-risk groups: older patients and those with a history of hypertension. Further, this study showed that advanced age and hypertension as a coexisting disease prior to parathyroid surgery were independent risk factors for the occurrence of IOH.
PB  - Karger, Basel
T2  - Medical Principles & Practice
T1  - Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism
VL  - 26
IS  - 4
SP  - 381
EP  - 386
DO  - 10.1159/000475597
ER  - 

@article{
author = "Sabljak, Vera and Živaljević, Vladan and Miličić, Biljana and Paunović, Ivan and Tosković, Anka R. and Stevanović, Ksenija and Taušanović, Katarina and Marković, Dejan Z. and Stojanović, Marina and Lakićević, Mirko and Jovanović, Milan D. and Diklić, Aleksandar and Kalezić, Nevena",
year = "2017",
abstract = "Objective: To investigate the incidence and identify risk factors for the occurrence of intraoperative hypertension (IOH) during surgery for primary hyperparathyroidism (pHPT). Subjects and Methods: The study included 269 patients surgically treated between January 2008 and January 2012 for pHPT. IOH was defined as an increase in systolic blood pressure >= 20% compared to baseline values which lasted for 15min. The investigated influence were demographic characteristics, surgical risk score related to physical status (based on the American Society of Anesthesiologists [ASA] classification), comorbidities, type and duration of surgery, and duration of anesthesia on IOH occurrence. The investigated factors were obtained from the patients' medical history, anesthesia charts, and the daily practice database. Logistic regression analysis was done to determine the predictors of IOH. Results: Of the 269 patients, 153 (56.9%) had IOH. Based on the univariate analysis, age, body mass index, ASA status, duration of anesthesia, and preoperative hypertension were risk factors for the occurrence of IOH. Multivariate analysis showed that independent predictors of IOH were a history of hypertension (OR = 2.080, 95% CI: 1.102-3.925, p = 0.024) and age (OR = 0.569, 95% CI: 0.360-0.901, p = 0.016). Conclusion: In this study, a high percentage (56%) of the patients developed IOH during surgery for pHPT, which indicates that special attention should be paid to these patients, especially to the high-risk groups: older patients and those with a history of hypertension. Further, this study showed that advanced age and hypertension as a coexisting disease prior to parathyroid surgery were independent risk factors for the occurrence of IOH.",
publisher = "Karger, Basel",
journal = "Medical Principles & Practice",
title = "Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism",
volume = "26",
number = "4",
pages = "381-386",
doi = "10.1159/000475597"
}

Sabljak, V., Živaljević, V., Miličić, B., Paunović, I., Tosković, A. R., Stevanović, K., Taušanović, K., Marković, D. Z., Stojanović, M., Lakićević, M., Jovanović, M. D., Diklić, A.,& Kalezić, N.. (2017). Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism. in Medical Principles & Practice
Karger, Basel., 26(4), 381-386.
https://doi.org/10.1159/000475597

Sabljak V, Živaljević V, Miličić B, Paunović I, Tosković AR, Stevanović K, Taušanović K, Marković DZ, Stojanović M, Lakićević M, Jovanović MD, Diklić A, Kalezić N. Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism. in Medical Principles & Practice. 2017;26(4):381-386.
doi:10.1159/000475597 .

Sabljak, Vera, Živaljević, Vladan, Miličić, Biljana, Paunović, Ivan, Tosković, Anka R., Stevanović, Ksenija, Taušanović, Katarina, Marković, Dejan Z., Stojanović, Marina, Lakićević, Mirko, Jovanović, Milan D., Diklić, Aleksandar, Kalezić, Nevena, "Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism" in Medical Principles & Practice, 26, no. 4 (2017):381-386,
https://doi.org/10.1159/000475597 . .

TY  - JOUR
AU  - Živaljević, Vladan
AU  - Taušanović, Katarina
AU  - Šipetić, Sandra
AU  - Paunović, Ivan
AU  - Diklić, Aleksandar
AU  - Kovačević, Bojan
AU  - Stojanović, Dragoš
AU  - Zivić, Rastko
AU  - Stanojević, Boban
AU  - Kalezić, Nevena
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1853
AB  - Thyroid carcinomas in children and adolescents are rare tumors and the most common among them is papillary thyroid cancer (PTC). Its etiology is still under research and has not been clearly defined thus far, especially in young individuals. The aim of this case-control study was to determine potential risk factors for the development of PTC in children and adolescents. This type of study has not been carried out previously in this age group. A case-control study was carried out during a 15-year period, between 1995 and 2009. The case group included 75 patients with PTC younger than 20 years of age, with the youngest patient being 6.5 years old; 45 patients were female and 30 were male. The control group included the same number of participants, and the cases were individually matched by sex, age, and place of residence. Conditional univariate and multivariate logistic regression methods were applied in data analysis. According to univariate logistic regression analysis, PTC in children and adolescents was significantly related to the following factors: family history of thyroid cancer, family history of residence in an endemic-goiter area, family history of benign thyroid disease, and family history of nonthyroid malignant tumors. According to the multivariate logistic regression method, PTC in children and adolescents was independently related to a family history of thyroid cancer (odds ratio=4.5, 95% confidence interval=1.2-19.8) and a family history of nonthyroid malignant tumors (odds ratio=3.8, 95% confidence interval=1.4-8.7). In conclusion, all of the factors associated with the development of PTC in children and adolescents were related to their family history.
PB  - Lippincott Williams & Wilkins, Philadelphia
T2  - European Journal of Cancer Prevention
T1  - A case-control study of papillary thyroid cancer in children and adolescents
VL  - 22
IS  - 6
SP  - 561
EP  - 565
DO  - 10.1097/CEJ.0b013e3283603494
ER  - 

@article{
author = "Živaljević, Vladan and Taušanović, Katarina and Šipetić, Sandra and Paunović, Ivan and Diklić, Aleksandar and Kovačević, Bojan and Stojanović, Dragoš and Zivić, Rastko and Stanojević, Boban and Kalezić, Nevena",
year = "2013",
abstract = "Thyroid carcinomas in children and adolescents are rare tumors and the most common among them is papillary thyroid cancer (PTC). Its etiology is still under research and has not been clearly defined thus far, especially in young individuals. The aim of this case-control study was to determine potential risk factors for the development of PTC in children and adolescents. This type of study has not been carried out previously in this age group. A case-control study was carried out during a 15-year period, between 1995 and 2009. The case group included 75 patients with PTC younger than 20 years of age, with the youngest patient being 6.5 years old; 45 patients were female and 30 were male. The control group included the same number of participants, and the cases were individually matched by sex, age, and place of residence. Conditional univariate and multivariate logistic regression methods were applied in data analysis. According to univariate logistic regression analysis, PTC in children and adolescents was significantly related to the following factors: family history of thyroid cancer, family history of residence in an endemic-goiter area, family history of benign thyroid disease, and family history of nonthyroid malignant tumors. According to the multivariate logistic regression method, PTC in children and adolescents was independently related to a family history of thyroid cancer (odds ratio=4.5, 95% confidence interval=1.2-19.8) and a family history of nonthyroid malignant tumors (odds ratio=3.8, 95% confidence interval=1.4-8.7). In conclusion, all of the factors associated with the development of PTC in children and adolescents were related to their family history.",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "European Journal of Cancer Prevention",
title = "A case-control study of papillary thyroid cancer in children and adolescents",
volume = "22",
number = "6",
pages = "561-565",
doi = "10.1097/CEJ.0b013e3283603494"
}

Živaljević, V., Taušanović, K., Šipetić, S., Paunović, I., Diklić, A., Kovačević, B., Stojanović, D., Zivić, R., Stanojević, B.,& Kalezić, N.. (2013). A case-control study of papillary thyroid cancer in children and adolescents. in European Journal of Cancer Prevention
Lippincott Williams & Wilkins, Philadelphia., 22(6), 561-565.
https://doi.org/10.1097/CEJ.0b013e3283603494

Živaljević V, Taušanović K, Šipetić S, Paunović I, Diklić A, Kovačević B, Stojanović D, Zivić R, Stanojević B, Kalezić N. A case-control study of papillary thyroid cancer in children and adolescents. in European Journal of Cancer Prevention. 2013;22(6):561-565.
doi:10.1097/CEJ.0b013e3283603494 .

Živaljević, Vladan, Taušanović, Katarina, Šipetić, Sandra, Paunović, Ivan, Diklić, Aleksandar, Kovačević, Bojan, Stojanović, Dragoš, Zivić, Rastko, Stanojević, Boban, Kalezić, Nevena, "A case-control study of papillary thyroid cancer in children and adolescents" in European Journal of Cancer Prevention, 22, no. 6 (2013):561-565,
https://doi.org/10.1097/CEJ.0b013e3283603494 . .

TY  - JOUR
AU  - Kalezić, Nevena
AU  - Stojanović, Marina
AU  - Miličić, Biljana
AU  - Antonijević, Vesna
AU  - Sabljak, Vera
AU  - Marković, Dejan
AU  - Živaljević, Vladan
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1851
AB  - We studied the influence of demographic characteristics, comorbidity, and type and duration of surgery and anesthesia on the occurrence of intraoperative hypertension (IOHTA). Logistic regression analyses were used in order to determine the predictors of occurrence of IOHTA. More than 60% of our patients had IOHTA. Multivariate analysis showed that independent predictors for IOHTA were older age, BMI > 25 kg/m(2), and hypertension as a coexisting disease. Hypertension is common during thyroid surgery, and a significant number of patients remained hypertensive during the postoperative period.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Clinical & Experimental Hypertension
T1  - The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery
VL  - 35
IS  - 7
SP  - 523
EP  - 527
DO  - 10.3109/10641963.2012.758735
ER  - 

@article{
author = "Kalezić, Nevena and Stojanović, Marina and Miličić, Biljana and Antonijević, Vesna and Sabljak, Vera and Marković, Dejan and Živaljević, Vladan",
year = "2013",
abstract = "We studied the influence of demographic characteristics, comorbidity, and type and duration of surgery and anesthesia on the occurrence of intraoperative hypertension (IOHTA). Logistic regression analyses were used in order to determine the predictors of occurrence of IOHTA. More than 60% of our patients had IOHTA. Multivariate analysis showed that independent predictors for IOHTA were older age, BMI > 25 kg/m(2), and hypertension as a coexisting disease. Hypertension is common during thyroid surgery, and a significant number of patients remained hypertensive during the postoperative period.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Clinical & Experimental Hypertension",
title = "The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery",
volume = "35",
number = "7",
pages = "523-527",
doi = "10.3109/10641963.2012.758735"
}

Kalezić, N., Stojanović, M., Miličić, B., Antonijević, V., Sabljak, V., Marković, D.,& Živaljević, V.. (2013). The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery. in Clinical & Experimental Hypertension
Taylor & Francis Inc, Philadelphia., 35(7), 523-527.
https://doi.org/10.3109/10641963.2012.758735

Kalezić N, Stojanović M, Miličić B, Antonijević V, Sabljak V, Marković D, Živaljević V. The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery. in Clinical & Experimental Hypertension. 2013;35(7):523-527.
doi:10.3109/10641963.2012.758735 .

Kalezić, Nevena, Stojanović, Marina, Miličić, Biljana, Antonijević, Vesna, Sabljak, Vera, Marković, Dejan, Živaljević, Vladan, "The Incidence of Intraoperative Hypertension and Risk Factors for its Development during Thyroid Surgery" in Clinical & Experimental Hypertension, 35, no. 7 (2013):523-527,
https://doi.org/10.3109/10641963.2012.758735 . .

TY  - JOUR
AU  - Kovačević, Bojan
AU  - Ignjatović, Mile
AU  - Živaljević, Vladan
AU  - Ćuk, Vladimir
AU  - Scepanović, Milena
AU  - Petrović, Zaklina
AU  - Paunović, Ivan
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1710
AB  - The National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI (TM)) 2003 and Kidney Disease: Improving Global Outcomes (KDIGO) 2009 have established guidelines for the treatement of secondary hyperparathyroidism. This study evaluated the impact of parathyroidectomy to achieve recommended values for parathyroid hormone, calcium, phosphorus and CaxPO(4) product in dialysis patients with severe secondary hyperparathyroidism that is resistant to medical treatment. This study included 43 consecutive patients who underwent parathyroidectomy for a severe form of secondary hyperparathyroidism (SHPT) that is unresponsive to medical treatment. The serum iPTH, calcium and phosphorus levels were measured prior to surgery, every morning after surgery for 5 days and on the first, sixth and eighth postoperative months. Following parathyroidectomy, a significant decline in iPTH values was observed in all patients; however, after the 8-month study period, only one of these patients achieved a serum iPTH concentration within the K/DOQI recommended target range. Unlike iPTH, targeting for calcium, phosphorus and CaxPO(4) at the last follow-up were 55.8%, 60.5% and 93%, respectively. These values indicated a significant improvement in comparison to preoperative percentages. In regards to the KDIGO recommended guidelines, the iPTH levels did not significantly change at the end of our study compared to preoperative values; however, calcium levels significantly declined and phosphorus levels significantly improved compared to preoperative values. Although the majority of patients fail to reach recommended iPTH values, parathyroidectomy remains a valuable tool to attain these NKF-K/DOQI recommendations for serum calcium, phosphorus and CaxPO(4) in dialysis patients with secondary hyperparathyroidism resistant to medical therapy. Parathyroidectomy was shown to be an inadequate intervention for achieving KDIGO recommendations.
PB  - Springer, New York
T2  - Langenbecks Archives of Surgery
T1  - Parathyroidectomy for the attainment of NKF-K/DOQI (TM) and KDIGO recommended values for bone and mineral metabolism in dialysis patients with uncontrollable secondary hyperparathyroidism
VL  - 397
IS  - 3
SP  - 413
EP  - 420
DO  - 10.1007/s00423-011-0901-9
ER  - 

@article{
author = "Kovačević, Bojan and Ignjatović, Mile and Živaljević, Vladan and Ćuk, Vladimir and Scepanović, Milena and Petrović, Zaklina and Paunović, Ivan",
year = "2012",
abstract = "The National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI (TM)) 2003 and Kidney Disease: Improving Global Outcomes (KDIGO) 2009 have established guidelines for the treatement of secondary hyperparathyroidism. This study evaluated the impact of parathyroidectomy to achieve recommended values for parathyroid hormone, calcium, phosphorus and CaxPO(4) product in dialysis patients with severe secondary hyperparathyroidism that is resistant to medical treatment. This study included 43 consecutive patients who underwent parathyroidectomy for a severe form of secondary hyperparathyroidism (SHPT) that is unresponsive to medical treatment. The serum iPTH, calcium and phosphorus levels were measured prior to surgery, every morning after surgery for 5 days and on the first, sixth and eighth postoperative months. Following parathyroidectomy, a significant decline in iPTH values was observed in all patients; however, after the 8-month study period, only one of these patients achieved a serum iPTH concentration within the K/DOQI recommended target range. Unlike iPTH, targeting for calcium, phosphorus and CaxPO(4) at the last follow-up were 55.8%, 60.5% and 93%, respectively. These values indicated a significant improvement in comparison to preoperative percentages. In regards to the KDIGO recommended guidelines, the iPTH levels did not significantly change at the end of our study compared to preoperative values; however, calcium levels significantly declined and phosphorus levels significantly improved compared to preoperative values. Although the majority of patients fail to reach recommended iPTH values, parathyroidectomy remains a valuable tool to attain these NKF-K/DOQI recommendations for serum calcium, phosphorus and CaxPO(4) in dialysis patients with secondary hyperparathyroidism resistant to medical therapy. Parathyroidectomy was shown to be an inadequate intervention for achieving KDIGO recommendations.",
publisher = "Springer, New York",
journal = "Langenbecks Archives of Surgery",
title = "Parathyroidectomy for the attainment of NKF-K/DOQI (TM) and KDIGO recommended values for bone and mineral metabolism in dialysis patients with uncontrollable secondary hyperparathyroidism",
volume = "397",
number = "3",
pages = "413-420",
doi = "10.1007/s00423-011-0901-9"
}

Kovačević, B., Ignjatović, M., Živaljević, V., Ćuk, V., Scepanović, M., Petrović, Z.,& Paunović, I.. (2012). Parathyroidectomy for the attainment of NKF-K/DOQI (TM) and KDIGO recommended values for bone and mineral metabolism in dialysis patients with uncontrollable secondary hyperparathyroidism. in Langenbecks Archives of Surgery
Springer, New York., 397(3), 413-420.
https://doi.org/10.1007/s00423-011-0901-9

Kovačević B, Ignjatović M, Živaljević V, Ćuk V, Scepanović M, Petrović Z, Paunović I. Parathyroidectomy for the attainment of NKF-K/DOQI (TM) and KDIGO recommended values for bone and mineral metabolism in dialysis patients with uncontrollable secondary hyperparathyroidism. in Langenbecks Archives of Surgery. 2012;397(3):413-420.
doi:10.1007/s00423-011-0901-9 .

Kovačević, Bojan, Ignjatović, Mile, Živaljević, Vladan, Ćuk, Vladimir, Scepanović, Milena, Petrović, Zaklina, Paunović, Ivan, "Parathyroidectomy for the attainment of NKF-K/DOQI (TM) and KDIGO recommended values for bone and mineral metabolism in dialysis patients with uncontrollable secondary hyperparathyroidism" in Langenbecks Archives of Surgery, 397, no. 3 (2012):413-420,
https://doi.org/10.1007/s00423-011-0901-9 . .

TY  - JOUR
AU  - Kovačević, Bojan
AU  - Ignjatović, M.
AU  - Ćuk, Vladimir
AU  - Živaljević, Vladan
AU  - Paunović, Ivan
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1662
AB  - Background : Hypocalcemia is the most common postoperative complication after total thyroidectomy. The aim of this prospective study was to determine biochemical parameters in the early postoperative period that could identify patients with significantly increased risk of symptomatic hypocalcemia development. Methods : The study included 100 individuals undergoing total thyroidectomy from January to May 2009. In all patients PTH, calcium, inorganic phosphate, magnesium, and albumin levels were measured immediately preoperatively, 30 minutes postoperatively and every morning for the following five days. Results : Clinically significant hypocalcemia was observed in 19% of all cases. Fall of the iPTH values by more than 88% from preoperative values, 30 min after completion of the surgery, showed 100% sensitivity and 100% specificity for the occurrence of symptomatic hypocalcemia. Conclusions : According to our results immediate postoperative measurement of the iPTH may be considered as a useful method to predict with high certainty which patients will need calcium supplementation, and to separate them from patients who can be safely and early discharged.
PB  - Acta Medical Belgica, Brussels
T2  - Acta Chirurgica Belgica
T1  - Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy
VL  - 111
IS  - 5
SP  - 303
EP  - 307
DO  - 10.1080/00015458.2011.11680758
ER  - 

@article{
author = "Kovačević, Bojan and Ignjatović, M. and Ćuk, Vladimir and Živaljević, Vladan and Paunović, Ivan",
year = "2011",
abstract = "Background : Hypocalcemia is the most common postoperative complication after total thyroidectomy. The aim of this prospective study was to determine biochemical parameters in the early postoperative period that could identify patients with significantly increased risk of symptomatic hypocalcemia development. Methods : The study included 100 individuals undergoing total thyroidectomy from January to May 2009. In all patients PTH, calcium, inorganic phosphate, magnesium, and albumin levels were measured immediately preoperatively, 30 minutes postoperatively and every morning for the following five days. Results : Clinically significant hypocalcemia was observed in 19% of all cases. Fall of the iPTH values by more than 88% from preoperative values, 30 min after completion of the surgery, showed 100% sensitivity and 100% specificity for the occurrence of symptomatic hypocalcemia. Conclusions : According to our results immediate postoperative measurement of the iPTH may be considered as a useful method to predict with high certainty which patients will need calcium supplementation, and to separate them from patients who can be safely and early discharged.",
publisher = "Acta Medical Belgica, Brussels",
journal = "Acta Chirurgica Belgica",
title = "Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy",
volume = "111",
number = "5",
pages = "303-307",
doi = "10.1080/00015458.2011.11680758"
}

Kovačević, B., Ignjatović, M., Ćuk, V., Živaljević, V.,& Paunović, I.. (2011). Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy. in Acta Chirurgica Belgica
Acta Medical Belgica, Brussels., 111(5), 303-307.
https://doi.org/10.1080/00015458.2011.11680758

Kovačević B, Ignjatović M, Ćuk V, Živaljević V, Paunović I. Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy. in Acta Chirurgica Belgica. 2011;111(5):303-307.
doi:10.1080/00015458.2011.11680758 .

Kovačević, Bojan, Ignjatović, M., Ćuk, Vladimir, Živaljević, Vladan, Paunović, Ivan, "Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy" in Acta Chirurgica Belgica, 111, no. 5 (2011):303-307,
https://doi.org/10.1080/00015458.2011.11680758 . .

TY  - JOUR
AU  - Bukvić, B.
AU  - Šipetić, Sandra
AU  - Kalezić, Nevena
AU  - Diklić, Aleksandar
AU  - Paunović, Ivan
AU  - Kovačević, Bojan
AU  - Knežević, Aleksandra
AU  - Živaljević, Vladan
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1631
AB  - Purpose: Thyroid cancer patients have favorable prognosis. The aim of this study was to analyze changing trends in mortality of thyroid cancer in Belgrade, during the period between 1987 and 2006 Methods: Mortality data were obtained from the Belgrade Office of Statistics. Mortality rates per 100,000 inhabitants were standardized according to the Segi's world population. Regression analysis was used to estimate the thyroid cancer mortality trend for the period 1987-2006. Results: The average percent of deaths due to thyroid cancer among all deaths was almost 2-fold higher in females (0.11%) than in males (0.6%), as well as among deaths due to all malignancies (females 0.54% and males 0.27%). During this 20-year period, the average standardized mortality rate was 1.5 times higher in females (0.74 per 100.000) than in males (0.51 per 100.000). In the observed period, the mortality rates for thyroid cancer were increased (+0.40%) in women and decreased (-0.42%) in men. In particular, in the 60-69 years age group in males, a significant trend for mortality decrease of 3.5%/year was detected. Conclusion: Belgrade is classified in the regions with low risk of dying due to thyroid malignancies. The increasing trend of thyroid cancer mortality in females during the examined period calls for improvement of methods for early detection of disease and differential diagnosis of thyroid nodules, so that surgical treatment of thyroid cancer could be performed at a stage when it is not life threatening.
PB  - Balkan Union of Oncology (B.U.ON.)
T2  - Journal of BUON
T1  - Changing trends in mortality of thyroid cancer in Belgrade population
VL  - 16
IS  - 2
SP  - 337
EP  - 340
UR  - https://hdl.handle.net/21.15107/rcub_smile_1631
ER  - 

@article{
author = "Bukvić, B. and Šipetić, Sandra and Kalezić, Nevena and Diklić, Aleksandar and Paunović, Ivan and Kovačević, Bojan and Knežević, Aleksandra and Živaljević, Vladan",
year = "2011",
abstract = "Purpose: Thyroid cancer patients have favorable prognosis. The aim of this study was to analyze changing trends in mortality of thyroid cancer in Belgrade, during the period between 1987 and 2006 Methods: Mortality data were obtained from the Belgrade Office of Statistics. Mortality rates per 100,000 inhabitants were standardized according to the Segi's world population. Regression analysis was used to estimate the thyroid cancer mortality trend for the period 1987-2006. Results: The average percent of deaths due to thyroid cancer among all deaths was almost 2-fold higher in females (0.11%) than in males (0.6%), as well as among deaths due to all malignancies (females 0.54% and males 0.27%). During this 20-year period, the average standardized mortality rate was 1.5 times higher in females (0.74 per 100.000) than in males (0.51 per 100.000). In the observed period, the mortality rates for thyroid cancer were increased (+0.40%) in women and decreased (-0.42%) in men. In particular, in the 60-69 years age group in males, a significant trend for mortality decrease of 3.5%/year was detected. Conclusion: Belgrade is classified in the regions with low risk of dying due to thyroid malignancies. The increasing trend of thyroid cancer mortality in females during the examined period calls for improvement of methods for early detection of disease and differential diagnosis of thyroid nodules, so that surgical treatment of thyroid cancer could be performed at a stage when it is not life threatening.",
publisher = "Balkan Union of Oncology (B.U.ON.)",
journal = "Journal of BUON",
title = "Changing trends in mortality of thyroid cancer in Belgrade population",
volume = "16",
number = "2",
pages = "337-340",
url = "https://hdl.handle.net/21.15107/rcub_smile_1631"
}

Bukvić, B., Šipetić, S., Kalezić, N., Diklić, A., Paunović, I., Kovačević, B., Knežević, A.,& Živaljević, V.. (2011). Changing trends in mortality of thyroid cancer in Belgrade population. in Journal of BUON
Balkan Union of Oncology (B.U.ON.)., 16(2), 337-340.
https://hdl.handle.net/21.15107/rcub_smile_1631

Bukvić B, Šipetić S, Kalezić N, Diklić A, Paunović I, Kovačević B, Knežević A, Živaljević V. Changing trends in mortality of thyroid cancer in Belgrade population. in Journal of BUON. 2011;16(2):337-340.
https://hdl.handle.net/21.15107/rcub_smile_1631 .

Bukvić, B., Šipetić, Sandra, Kalezić, Nevena, Diklić, Aleksandar, Paunović, Ivan, Kovačević, Bojan, Knežević, Aleksandra, Živaljević, Vladan, "Changing trends in mortality of thyroid cancer in Belgrade population" in Journal of BUON, 16, no. 2 (2011):337-340,
https://hdl.handle.net/21.15107/rcub_smile_1631 .