TY  - JOUR
AU  - Krunic, Jelena
AU  - Mladenović, Irena
AU  - Radović, Ivana
AU  - Stojanović, Nikola
PY  - 2021
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2574
AB  - Background
Menstrual cycle may contribute to experimental pain measures in healthy women and women with chronic pain.

Objectives
The present study aimed to investigate variation in pulp sensitivity across the menstrual cycle in healthy women and women with temporomandibular disorders (TMD) and to explore the effect of TMD pain and psychosocial variables on the pulp response.

Methods
This longitudinal study involved 47 regularly menstruating women aged 20‐45, 24 healthy and 23 with diagnosed painful TMD. The electric and cold stimuli were performed by electric pulp tester and refrigerant spray, respectively, on mandibular lateral incisors, in five menstrual phases (menstrual, follicular, periovulatory, luteal and premenstrual). Research Diagnostic Criteria for TMD were used to assess TMD, chronic pain, depression and somatisation. Regression analysis was performed to investigate the effect of the predictor variables on the pulp sensitivity.

Results
Significant phase‐related differences were observed for pain intensity to cold stimuli. Higher pain sensitivity was reported in menstrual in comparison with luteal phase (P = .019) among healthy women, and in menstrual in comparison with follicular (P = .033), periovulatory (P = .003) and luteal (P = .007) phases in TMD women. No significant differences were recorded for electric stimuli. Regression analysis identified depression as the determinant of cold and electric response in menstrual phase, regardless of age and presence of TMD.

Conclusion
Menstrual phase in healthy and TMD women with regular menstrual cycle is characterised with higher pulp sensitivity to cold stimuli. Depressive symptoms independently influence pulp response in this phase.
PB  - Wiley
T2  - Journal of Oral Rehabilitationa
T1  - Changes in pulp sensitivity across the menstrual cycle in healthy women and women with temporomandibular disorders
VL  - 48
IS  - 2
SP  - 124
EP  - 131
DO  - 10.1111/joor.13116
ER  - 

@article{
author = "Krunic, Jelena and Mladenović, Irena and Radović, Ivana and Stojanović, Nikola",
year = "2021",
abstract = "Background
Menstrual cycle may contribute to experimental pain measures in healthy women and women with chronic pain.

Objectives
The present study aimed to investigate variation in pulp sensitivity across the menstrual cycle in healthy women and women with temporomandibular disorders (TMD) and to explore the effect of TMD pain and psychosocial variables on the pulp response.

Methods
This longitudinal study involved 47 regularly menstruating women aged 20‐45, 24 healthy and 23 with diagnosed painful TMD. The electric and cold stimuli were performed by electric pulp tester and refrigerant spray, respectively, on mandibular lateral incisors, in five menstrual phases (menstrual, follicular, periovulatory, luteal and premenstrual). Research Diagnostic Criteria for TMD were used to assess TMD, chronic pain, depression and somatisation. Regression analysis was performed to investigate the effect of the predictor variables on the pulp sensitivity.

Results
Significant phase‐related differences were observed for pain intensity to cold stimuli. Higher pain sensitivity was reported in menstrual in comparison with luteal phase (P = .019) among healthy women, and in menstrual in comparison with follicular (P = .033), periovulatory (P = .003) and luteal (P = .007) phases in TMD women. No significant differences were recorded for electric stimuli. Regression analysis identified depression as the determinant of cold and electric response in menstrual phase, regardless of age and presence of TMD.

Conclusion
Menstrual phase in healthy and TMD women with regular menstrual cycle is characterised with higher pulp sensitivity to cold stimuli. Depressive symptoms independently influence pulp response in this phase.",
publisher = "Wiley",
journal = "Journal of Oral Rehabilitationa",
title = "Changes in pulp sensitivity across the menstrual cycle in healthy women and women with temporomandibular disorders",
volume = "48",
number = "2",
pages = "124-131",
doi = "10.1111/joor.13116"
}

Krunic, J., Mladenović, I., Radović, I.,& Stojanović, N.. (2021). Changes in pulp sensitivity across the menstrual cycle in healthy women and women with temporomandibular disorders. in Journal of Oral Rehabilitationa
Wiley., 48(2), 124-131.
https://doi.org/10.1111/joor.13116

Krunic J, Mladenović I, Radović I, Stojanović N. Changes in pulp sensitivity across the menstrual cycle in healthy women and women with temporomandibular disorders. in Journal of Oral Rehabilitationa. 2021;48(2):124-131.
doi:10.1111/joor.13116 .

Krunic, Jelena, Mladenović, Irena, Radović, Ivana, Stojanović, Nikola, "Changes in pulp sensitivity across the menstrual cycle in healthy women and women with temporomandibular disorders" in Journal of Oral Rehabilitationa, 48, no. 2 (2021):124-131,
https://doi.org/10.1111/joor.13116 . .

TY  - JOUR
AU  - Popovac, Aleksandra
AU  - Mladenović, Irena
AU  - Krunić, Jelena
AU  - Trifković, Branka
AU  - Todorović, Ana
AU  - Milašin, Jelena
AU  - Despotović, Nebojša
AU  - Stančić, Ivica
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2517
AB  - Compromised dentition has been suggested to pose a significant risk factor for dementia. It was mainly investigated through insufficient tooth number, disregarding contact between opposing teeth (dental occlusion). The epsilon 4 allele of apolipoprotein (APOE4) is the primary genetic marker for the late onset of Alzheimer's disease (AD). However, APOE4 and dental occlusion have not yet been investigated as possible associated risk factors for AD. The study was aimed to examine the impact of dental status and different APOE gene variants on AD occurrence. Secondly, sociodemographic variables were investigated as factors potentially associated with AD. The case-control study included two groups: 116 patients with AD (according to the NINDS-ADRDA criteria) and 63 controls (Mini-Mental State Examination scores >= 24). The analysis of APOE gene polymorphism was conducted through PCR reaction. Dental examination included recording of number of teeth, presence of fixed or removable dentures, and number of functional tooth units (FTU). Regression analysis was used to investigate the joint effect of the clinical and genetic variables on AD. Results showed that patients with AD were more often carriers of epsilon 3/epsilon 4 genotype and epsilon 4 allele, had lower number of teeth and FTU, and were less likely to be married, live in home, and had less chronic diseases, compared to the controls. Regression analysis showed that presence of APOE4 allele and the number of total FTU remained associated with AD, even when adjusted for age, sex, and level of education. In conclusion, deficient dental occlusion and presence of APOE4 may independently increase risk for AD.
PB  - Ios Press, Amsterdam
T2  - Journal of Alzheimers Disease
T1  - Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease
VL  - 74
IS  - 3
SP  - 797
EP  - 802
DO  - 10.3233/JAD-191283
ER  - 

@article{
author = "Popovac, Aleksandra and Mladenović, Irena and Krunić, Jelena and Trifković, Branka and Todorović, Ana and Milašin, Jelena and Despotović, Nebojša and Stančić, Ivica",
year = "2020",
abstract = "Compromised dentition has been suggested to pose a significant risk factor for dementia. It was mainly investigated through insufficient tooth number, disregarding contact between opposing teeth (dental occlusion). The epsilon 4 allele of apolipoprotein (APOE4) is the primary genetic marker for the late onset of Alzheimer's disease (AD). However, APOE4 and dental occlusion have not yet been investigated as possible associated risk factors for AD. The study was aimed to examine the impact of dental status and different APOE gene variants on AD occurrence. Secondly, sociodemographic variables were investigated as factors potentially associated with AD. The case-control study included two groups: 116 patients with AD (according to the NINDS-ADRDA criteria) and 63 controls (Mini-Mental State Examination scores >= 24). The analysis of APOE gene polymorphism was conducted through PCR reaction. Dental examination included recording of number of teeth, presence of fixed or removable dentures, and number of functional tooth units (FTU). Regression analysis was used to investigate the joint effect of the clinical and genetic variables on AD. Results showed that patients with AD were more often carriers of epsilon 3/epsilon 4 genotype and epsilon 4 allele, had lower number of teeth and FTU, and were less likely to be married, live in home, and had less chronic diseases, compared to the controls. Regression analysis showed that presence of APOE4 allele and the number of total FTU remained associated with AD, even when adjusted for age, sex, and level of education. In conclusion, deficient dental occlusion and presence of APOE4 may independently increase risk for AD.",
publisher = "Ios Press, Amsterdam",
journal = "Journal of Alzheimers Disease",
title = "Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease",
volume = "74",
number = "3",
pages = "797-802",
doi = "10.3233/JAD-191283"
}

Popovac, A., Mladenović, I., Krunić, J., Trifković, B., Todorović, A., Milašin, J., Despotović, N.,& Stančić, I.. (2020). Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease. in Journal of Alzheimers Disease
Ios Press, Amsterdam., 74(3), 797-802.
https://doi.org/10.3233/JAD-191283

Popovac A, Mladenović I, Krunić J, Trifković B, Todorović A, Milašin J, Despotović N, Stančić I. Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease. in Journal of Alzheimers Disease. 2020;74(3):797-802.
doi:10.3233/JAD-191283 .

Popovac, Aleksandra, Mladenović, Irena, Krunić, Jelena, Trifković, Branka, Todorović, Ana, Milašin, Jelena, Despotović, Nebojša, Stančić, Ivica, "Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease" in Journal of Alzheimers Disease, 74, no. 3 (2020):797-802,
https://doi.org/10.3233/JAD-191283 . .

TY  - JOUR
AU  - Stojanović, Nikola
AU  - Krunić, Jelena
AU  - Mladenović, Irena
AU  - Stojanović, Zorica
AU  - Apostolska, Sonja
AU  - Živković, Slavoljub
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2354
AB  - Introduction/Objective The aim of this study was to determine clinical and radiographic periapical healing of teeth with apical periodontitis treated with different formulations of calcium hydroxide (CH) - paste (CH-paste) and gutta-percha points (CH-GP) - as well as those of chlorhexidine (CHX) - gel (CHXgel) and gutta-percha points (CHX-GP) -12 months after therapy. Methods Eighty patients with chronic apical periodontitis were randomly allocated to four treatment groups according to the intracanal medicament used: CH-paste, CH-GP, CHX-gel, and CHX-GP group. Seventy-eight patients were analyzed clinically and radiographically 12 months postoperatively. The periapical index (PAI) was used for the radiographic evaluation of treatment. Results Overall outcome was classified according to radiographic evaluation only, since clinical success was observed in all the patients. In all the groups, significant reduction in PAI scores was observed (p  lt  0.001). The proportions of healed teeth (PAI ≤ 2) were 73.7%, 60%, 68.4%, and 65% in CH-paste, CH-GP, CHX-gel and CHX-GP group, respectively, with no significant differences between the groups. Conclusion The results suggest that there are no differences between investigated CH- and CHX-delivery systems regarding treatment outcome of teeth with apical periodontitis.
AB  - Uvod/Cilj Cilj ovog istraživanja je bio da se ispita klinički i radiografski ishod lečenja zuba sa apeksnim periodontitisom 12 meseci posle završene terapije i primene različitih oblika kalcijum-hidroksida (KH): pasta (KH-pasta) i gutaperka poeni (KH-GP) i hlorheksidina (HH): gel (HH-gel) i gutaperka poeni (HH-GP). Metode Randomizovano je 80 ispitanika sa hroničnim periapeksnim lezijama u četiri grupe na osnovu vrste korišćenog interseansnog medikamenta: KH-pasta, KH-GP, HH-gel i HH-GP. Dvanaest meseci posle završenog lečenja pregledano je 78 ispitanika i urađeni su retroalveolarni snimci. Za procenu radiografskog uspeha lečenja korišćen je periapikalni indeks (PI). Rezultati Ishod lečenja je klasifikovan na osnovu radiološkog nalaza jer je kod svih ispitanika zabeležen klinički uspeh lečenja. U svim ispitivanim grupama je zabeleženo značajno smanjenje vrednosti PI (p  lt  0,001). Izlečenje (PI ≤ 2) uočeno je kod 73,3% zuba u grupi KH-pasta, 60% u KH-GP grupi, 68,4% u grupi HH-gel i kod 65% zuba u grupi HH-GP, pri čemu razlike između grupa nisu bile statistički značajne. Zaključak Rezultati ovog istraživanja pokazuju da ne postoji razlika u ishodu lečenja zuba sa apeksnim periodontitisom posle primene ispitivanih oblika KH i HH.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis
T1  - Uticaj različitih oblika kalcijum-hidroksida i hlorheksidina kao interseansnih medikamenata na ishod endodontskog lečenja zuba sa hroničnim periapeksnim lezijama
VL  - 146
IS  - 3-4
SP  - 143
EP  - 148
DO  - 10.2298/SARH170221139S
ER  - 

@article{
author = "Stojanović, Nikola and Krunić, Jelena and Mladenović, Irena and Stojanović, Zorica and Apostolska, Sonja and Živković, Slavoljub",
year = "2018",
abstract = "Introduction/Objective The aim of this study was to determine clinical and radiographic periapical healing of teeth with apical periodontitis treated with different formulations of calcium hydroxide (CH) - paste (CH-paste) and gutta-percha points (CH-GP) - as well as those of chlorhexidine (CHX) - gel (CHXgel) and gutta-percha points (CHX-GP) -12 months after therapy. Methods Eighty patients with chronic apical periodontitis were randomly allocated to four treatment groups according to the intracanal medicament used: CH-paste, CH-GP, CHX-gel, and CHX-GP group. Seventy-eight patients were analyzed clinically and radiographically 12 months postoperatively. The periapical index (PAI) was used for the radiographic evaluation of treatment. Results Overall outcome was classified according to radiographic evaluation only, since clinical success was observed in all the patients. In all the groups, significant reduction in PAI scores was observed (p  lt  0.001). The proportions of healed teeth (PAI ≤ 2) were 73.7%, 60%, 68.4%, and 65% in CH-paste, CH-GP, CHX-gel and CHX-GP group, respectively, with no significant differences between the groups. Conclusion The results suggest that there are no differences between investigated CH- and CHX-delivery systems regarding treatment outcome of teeth with apical periodontitis., Uvod/Cilj Cilj ovog istraživanja je bio da se ispita klinički i radiografski ishod lečenja zuba sa apeksnim periodontitisom 12 meseci posle završene terapije i primene različitih oblika kalcijum-hidroksida (KH): pasta (KH-pasta) i gutaperka poeni (KH-GP) i hlorheksidina (HH): gel (HH-gel) i gutaperka poeni (HH-GP). Metode Randomizovano je 80 ispitanika sa hroničnim periapeksnim lezijama u četiri grupe na osnovu vrste korišćenog interseansnog medikamenta: KH-pasta, KH-GP, HH-gel i HH-GP. Dvanaest meseci posle završenog lečenja pregledano je 78 ispitanika i urađeni su retroalveolarni snimci. Za procenu radiografskog uspeha lečenja korišćen je periapikalni indeks (PI). Rezultati Ishod lečenja je klasifikovan na osnovu radiološkog nalaza jer je kod svih ispitanika zabeležen klinički uspeh lečenja. U svim ispitivanim grupama je zabeleženo značajno smanjenje vrednosti PI (p  lt  0,001). Izlečenje (PI ≤ 2) uočeno je kod 73,3% zuba u grupi KH-pasta, 60% u KH-GP grupi, 68,4% u grupi HH-gel i kod 65% zuba u grupi HH-GP, pri čemu razlike između grupa nisu bile statistički značajne. Zaključak Rezultati ovog istraživanja pokazuju da ne postoji razlika u ishodu lečenja zuba sa apeksnim periodontitisom posle primene ispitivanih oblika KH i HH.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis, Uticaj različitih oblika kalcijum-hidroksida i hlorheksidina kao interseansnih medikamenata na ishod endodontskog lečenja zuba sa hroničnim periapeksnim lezijama",
volume = "146",
number = "3-4",
pages = "143-148",
doi = "10.2298/SARH170221139S"
}

Stojanović, N., Krunić, J., Mladenović, I., Stojanović, Z., Apostolska, S.,& Živković, S.. (2018). Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 146(3-4), 143-148.
https://doi.org/10.2298/SARH170221139S

Stojanović N, Krunić J, Mladenović I, Stojanović Z, Apostolska S, Živković S. Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis. in Srpski arhiv za celokupno lekarstvo. 2018;146(3-4):143-148.
doi:10.2298/SARH170221139S .

Stojanović, Nikola, Krunić, Jelena, Mladenović, Irena, Stojanović, Zorica, Apostolska, Sonja, Živković, Slavoljub, "Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis" in Srpski arhiv za celokupno lekarstvo, 146, no. 3-4 (2018):143-148,
https://doi.org/10.2298/SARH170221139S . .

TY  - JOUR
AU  - Mladenović, Irena
AU  - Supić, Gordana
AU  - Kozomara, Ružica
AU  - Dodić, Slobodan
AU  - Ivković, Nedeljka
AU  - Milićević, Bojana
AU  - Simić, Ivana
AU  - Magić, Zvonko
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2124
AB  - Aims: To evaluate the association between catechol-O-methyltransferase (COMT) gene polymorphisms and temporomandibular disorders (TMD), TMD pain, psychosocial impairment related to TMD, and postoperative pain. Methods: A total of 90 patients with a diagnosis of painful TMD and 92 matched controls were investigated for the presence of TMD, TMD pain, and psychosocial variables by the Research Diagnostic Criteria for TMD. In a prospective cohort study of 40 subjects who underwent extraction of at least one fully impacted mandibular third molar, subjects had 6 months post-surgery follow-up of postoperative pain. DNA extracted from peripheral blood was genotyped for three COMT polymorphisms (rs4680, rs6269, and rs165774) by real-time TaqMan method. The association between COMT polymorphisms and clinical variables was determined by calculating odds ratios (OR) and their 95% confidence intervals (CO. Results: Homozygous AA genotype and heterozygous variant A allele carriers (genotype AG/AA) for rs165774 polymorphism were associated with increased risk of TMD compared to wild type (wt) GG genotype (OR = 9.448, P =.006; OR = 2.088, P =.017, respectively). In addition, AA genotype was associated with increased risk of arthralgia (OR = 4.448, P =.011), myofascial pain (OR = 3.543, P =.035), and chronic TMD pain (OR = 6.173, P =.006), compared to wt genotype. AA genotype for rs6269 polymorphism was related to less postoperative chronic TMD pain (P =.025) and lower postoperative acute pain at the extraction site (P =.030). No associations with depression and somatization were observed. Conclusion: AA genotype of rs165774 could be a significant risk factor for the development of TMD and TMD pain, while AA genotype of rs6269 presents less postoperative chronic TMD pain and acute pain at a dental extraction site.
PB  - Quintessence Publishing Co Inc, Hanover Park
T2  - Journal of Oral & Facial Pain & Headache
T1  - Genetic Polymorphisms of Catechol-O-Methyltransferase: Association with Temporomandibular Disorders and Postoperative Pain
VL  - 30
IS  - 4
SP  - 302
EP  - 310
DO  - 10.11607/ofph.1688
ER  - 

@article{
author = "Mladenović, Irena and Supić, Gordana and Kozomara, Ružica and Dodić, Slobodan and Ivković, Nedeljka and Milićević, Bojana and Simić, Ivana and Magić, Zvonko",
year = "2016",
abstract = "Aims: To evaluate the association between catechol-O-methyltransferase (COMT) gene polymorphisms and temporomandibular disorders (TMD), TMD pain, psychosocial impairment related to TMD, and postoperative pain. Methods: A total of 90 patients with a diagnosis of painful TMD and 92 matched controls were investigated for the presence of TMD, TMD pain, and psychosocial variables by the Research Diagnostic Criteria for TMD. In a prospective cohort study of 40 subjects who underwent extraction of at least one fully impacted mandibular third molar, subjects had 6 months post-surgery follow-up of postoperative pain. DNA extracted from peripheral blood was genotyped for three COMT polymorphisms (rs4680, rs6269, and rs165774) by real-time TaqMan method. The association between COMT polymorphisms and clinical variables was determined by calculating odds ratios (OR) and their 95% confidence intervals (CO. Results: Homozygous AA genotype and heterozygous variant A allele carriers (genotype AG/AA) for rs165774 polymorphism were associated with increased risk of TMD compared to wild type (wt) GG genotype (OR = 9.448, P =.006; OR = 2.088, P =.017, respectively). In addition, AA genotype was associated with increased risk of arthralgia (OR = 4.448, P =.011), myofascial pain (OR = 3.543, P =.035), and chronic TMD pain (OR = 6.173, P =.006), compared to wt genotype. AA genotype for rs6269 polymorphism was related to less postoperative chronic TMD pain (P =.025) and lower postoperative acute pain at the extraction site (P =.030). No associations with depression and somatization were observed. Conclusion: AA genotype of rs165774 could be a significant risk factor for the development of TMD and TMD pain, while AA genotype of rs6269 presents less postoperative chronic TMD pain and acute pain at a dental extraction site.",
publisher = "Quintessence Publishing Co Inc, Hanover Park",
journal = "Journal of Oral & Facial Pain & Headache",
title = "Genetic Polymorphisms of Catechol-O-Methyltransferase: Association with Temporomandibular Disorders and Postoperative Pain",
volume = "30",
number = "4",
pages = "302-310",
doi = "10.11607/ofph.1688"
}

Mladenović, I., Supić, G., Kozomara, R., Dodić, S., Ivković, N., Milićević, B., Simić, I.,& Magić, Z.. (2016). Genetic Polymorphisms of Catechol-O-Methyltransferase: Association with Temporomandibular Disorders and Postoperative Pain. in Journal of Oral & Facial Pain & Headache
Quintessence Publishing Co Inc, Hanover Park., 30(4), 302-310.
https://doi.org/10.11607/ofph.1688

Mladenović I, Supić G, Kozomara R, Dodić S, Ivković N, Milićević B, Simić I, Magić Z. Genetic Polymorphisms of Catechol-O-Methyltransferase: Association with Temporomandibular Disorders and Postoperative Pain. in Journal of Oral & Facial Pain & Headache. 2016;30(4):302-310.
doi:10.11607/ofph.1688 .

Mladenović, Irena, Supić, Gordana, Kozomara, Ružica, Dodić, Slobodan, Ivković, Nedeljka, Milićević, Bojana, Simić, Ivana, Magić, Zvonko, "Genetic Polymorphisms of Catechol-O-Methyltransferase: Association with Temporomandibular Disorders and Postoperative Pain" in Journal of Oral & Facial Pain & Headache, 30, no. 4 (2016):302-310,
https://doi.org/10.11607/ofph.1688 . .

TY  - JOUR
AU  - Mladenović, Irena
AU  - Dodić, Slobodan
AU  - Stošić, Srboljub
AU  - Petrović, Dragan
AU  - Čutović, Tatjana
AU  - Kozomara, Ružica
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1989
PB  - Churchill Livingstone, Edinburgh
T2  - Journal of Cranio-Maxillofacial Surgery
T1  - TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects (vol 42, pg 1604, 2014)
VL  - 43
IS  - 3
SP  - 301
EP  - 301
DO  - 10.1016/j.jcms.2014.12.010
ER  - 

@article{
author = "Mladenović, Irena and Dodić, Slobodan and Stošić, Srboljub and Petrović, Dragan and Čutović, Tatjana and Kozomara, Ružica",
year = "2015",
publisher = "Churchill Livingstone, Edinburgh",
journal = "Journal of Cranio-Maxillofacial Surgery",
title = "TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects (vol 42, pg 1604, 2014)",
volume = "43",
number = "3",
pages = "301-301",
doi = "10.1016/j.jcms.2014.12.010"
}

Mladenović, I., Dodić, S., Stošić, S., Petrović, D., Čutović, T.,& Kozomara, R.. (2015). TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects (vol 42, pg 1604, 2014). in Journal of Cranio-Maxillofacial Surgery
Churchill Livingstone, Edinburgh., 43(3), 301-301.
https://doi.org/10.1016/j.jcms.2014.12.010

Mladenović I, Dodić S, Stošić S, Petrović D, Čutović T, Kozomara R. TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects (vol 42, pg 1604, 2014). in Journal of Cranio-Maxillofacial Surgery. 2015;43(3):301-301.
doi:10.1016/j.jcms.2014.12.010 .

Mladenović, Irena, Dodić, Slobodan, Stošić, Srboljub, Petrović, Dragan, Čutović, Tatjana, Kozomara, Ružica, "TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects (vol 42, pg 1604, 2014)" in Journal of Cranio-Maxillofacial Surgery, 43, no. 3 (2015):301-301,
https://doi.org/10.1016/j.jcms.2014.12.010 . .

TY  - JOUR
AU  - Čutović, Tatjana
AU  - Jović, Nebojša
AU  - Stojanović, Ljiljana
AU  - Radojičić, Julija
AU  - Mladenović, Irena
AU  - Matijević, Stevo
AU  - Kozomara, Ružica
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1940
AB  - Bacground/Aim. The literature suggests different views on the correlation between the cranial base morphology and size and saggital intermaxillary relationships. The aim of this study was to investigate the cranial base morphology, including the frontal facial part in patients with mandibular prognathism, to clarify a certain ambiguities, in opposing viewspoints in the literature. Methods. Cephalometric radiographies of 60 patients were analyzed at the Dental Clinic of the Military Medical Academy, Belgrade, Serbia. All the patients were male, aged 18-35 years, with no previous orthodontic treatment. On the basis of dental and sceletal relations of jaws and teeth, the patients were divided into two groups: the group P (patients with mandibular prognathism) and the group E (the control group or eugnathic patients). A total of 15 cephalometric parametres related to the cranial base, frontal part of the face and sagittal intermaxillary relationships were measured and analyzed. Results. The results show that cranial base dimensions and the angle do not play a significant role in the development of mandibular prognathism. Interrelationship analysis indicated a statistically significant negative correlation between the cranial base angle (NSAr) and the angles of maxillary (SNA) and mandibular (SNB) prognathism, as well as a positive correlation between the angle of inclination of the ramus to the cranial base (GoArNS) and the angle of sagittal intermaxillary relationships (ANB). Sella turcica dimensions, its width and depth, as well as the nasal bone length were significantly increased in the patients with mandibular prognathism, while the other analyzed frontal part dimensions of the face were not changed by the malocclusion in comparison with the eugnathic patients. Conclusion. This study shows that the impact of the cranial base and the frontal part of the face on the development of profile in patients with mandibular prognathism is much smaller, but certainly more complex, so that morphogenetic tests of the maxillomandibular complex should be included in further assessment of this impact.
AB  - Uvod/Cilj. U literaturi postoje različiti stavovi o povezanosti morfologije i veličine kranijalne baze i sagitalnih međuviličnih odnosa. Cilj ovog rada bio je da se ispita morfologija kranijalne baze, uključujući i prednji deo lica, kod ispitanika sa mandibularnim prognatizmom da bi se razjasnile nedoumice donekle suprotnih stavova u literaturi. Metode. Analizirani su rendgenkefalometrijski snimci ukupno 60 bolesnika Klinike za stomatologiju VMA. Svi bolesnici bili su muškog pola, starosti od 18 do 35 godina koji ranije nisu bili ortodontski lečeni. Bolesnici su prema dentoskeletnim odnosima vilica i zuba bili svrstani u dve grupe: grupu P (bolesnici sa mandibularnim prognatizmom) i grupu E (kontrolna grupa ili grupa eugnatih bolesnika). Izmereno je i analizirano 15 kefalometrijskih parametara koji su se odnosili na kranijalnu bazu, frontalni deo lica kao i sagitalne međuvilične odnose. Rezultati. Dobijeni rezultati ukazuju da ni dimenzije kranijalne baze, ni njen ugao ne igraju značajnu ulogu u nastanku mandibularnog prognatizma. Analizom međuzavisnosti ustanovljeno je da postoji statistički značajna negativna korelacija između ugla kranijalne baze (NSAr) i uglova maksilarnog (SNA) i mandibularnog (SNB) prognatizma, kao i pozitivna korelacija između ugla nagiba ramusa prema kranijalnoj bazi (GoArNS) i ugla sagitalnih međuviličnih odnosa (ANB). Dimenzije sedlaste jamice (sella turcica), njena širina i dubina, kao i dužina nosne kosti statistički su značajno povećane kod bolesnika sa mandibularnim prognatizmom, dok ostale analizirane dimenzije prednjeg dela lica nisu bile izmenjene kod ove malokluzije u odnosu na eugnate bolesnike. Zaključak. Pokazalo se da je uticaj kranijalne baze i prednjeg dela lica na ispoljavanje profila kod bolesnika sa mandibularnim prognatizmom mnogo manji ali svakako složeniji, pa bi u dalja istraživanja trebalo uključiti morfogenetska ispitivanja maksilomandibularnog kompleksa kod ocenjivanja ovog uticaja.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - A cephalometric analysis of the cranial base and frontal part of the face in patients with mandibular prognathism
T1  - Kefalometrijska analiza kranijalne baze i prednjeg dela lica kod osoba sa mandibularnim prognatizmom
VL  - 71
IS  - 6
SP  - 534
EP  - 541
DO  - 10.2298/VSP121212011C
ER  - 

@article{
author = "Čutović, Tatjana and Jović, Nebojša and Stojanović, Ljiljana and Radojičić, Julija and Mladenović, Irena and Matijević, Stevo and Kozomara, Ružica",
year = "2014",
abstract = "Bacground/Aim. The literature suggests different views on the correlation between the cranial base morphology and size and saggital intermaxillary relationships. The aim of this study was to investigate the cranial base morphology, including the frontal facial part in patients with mandibular prognathism, to clarify a certain ambiguities, in opposing viewspoints in the literature. Methods. Cephalometric radiographies of 60 patients were analyzed at the Dental Clinic of the Military Medical Academy, Belgrade, Serbia. All the patients were male, aged 18-35 years, with no previous orthodontic treatment. On the basis of dental and sceletal relations of jaws and teeth, the patients were divided into two groups: the group P (patients with mandibular prognathism) and the group E (the control group or eugnathic patients). A total of 15 cephalometric parametres related to the cranial base, frontal part of the face and sagittal intermaxillary relationships were measured and analyzed. Results. The results show that cranial base dimensions and the angle do not play a significant role in the development of mandibular prognathism. Interrelationship analysis indicated a statistically significant negative correlation between the cranial base angle (NSAr) and the angles of maxillary (SNA) and mandibular (SNB) prognathism, as well as a positive correlation between the angle of inclination of the ramus to the cranial base (GoArNS) and the angle of sagittal intermaxillary relationships (ANB). Sella turcica dimensions, its width and depth, as well as the nasal bone length were significantly increased in the patients with mandibular prognathism, while the other analyzed frontal part dimensions of the face were not changed by the malocclusion in comparison with the eugnathic patients. Conclusion. This study shows that the impact of the cranial base and the frontal part of the face on the development of profile in patients with mandibular prognathism is much smaller, but certainly more complex, so that morphogenetic tests of the maxillomandibular complex should be included in further assessment of this impact., Uvod/Cilj. U literaturi postoje različiti stavovi o povezanosti morfologije i veličine kranijalne baze i sagitalnih međuviličnih odnosa. Cilj ovog rada bio je da se ispita morfologija kranijalne baze, uključujući i prednji deo lica, kod ispitanika sa mandibularnim prognatizmom da bi se razjasnile nedoumice donekle suprotnih stavova u literaturi. Metode. Analizirani su rendgenkefalometrijski snimci ukupno 60 bolesnika Klinike za stomatologiju VMA. Svi bolesnici bili su muškog pola, starosti od 18 do 35 godina koji ranije nisu bili ortodontski lečeni. Bolesnici su prema dentoskeletnim odnosima vilica i zuba bili svrstani u dve grupe: grupu P (bolesnici sa mandibularnim prognatizmom) i grupu E (kontrolna grupa ili grupa eugnatih bolesnika). Izmereno je i analizirano 15 kefalometrijskih parametara koji su se odnosili na kranijalnu bazu, frontalni deo lica kao i sagitalne međuvilične odnose. Rezultati. Dobijeni rezultati ukazuju da ni dimenzije kranijalne baze, ni njen ugao ne igraju značajnu ulogu u nastanku mandibularnog prognatizma. Analizom međuzavisnosti ustanovljeno je da postoji statistički značajna negativna korelacija između ugla kranijalne baze (NSAr) i uglova maksilarnog (SNA) i mandibularnog (SNB) prognatizma, kao i pozitivna korelacija između ugla nagiba ramusa prema kranijalnoj bazi (GoArNS) i ugla sagitalnih međuviličnih odnosa (ANB). Dimenzije sedlaste jamice (sella turcica), njena širina i dubina, kao i dužina nosne kosti statistički su značajno povećane kod bolesnika sa mandibularnim prognatizmom, dok ostale analizirane dimenzije prednjeg dela lica nisu bile izmenjene kod ove malokluzije u odnosu na eugnate bolesnike. Zaključak. Pokazalo se da je uticaj kranijalne baze i prednjeg dela lica na ispoljavanje profila kod bolesnika sa mandibularnim prognatizmom mnogo manji ali svakako složeniji, pa bi u dalja istraživanja trebalo uključiti morfogenetska ispitivanja maksilomandibularnog kompleksa kod ocenjivanja ovog uticaja.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "A cephalometric analysis of the cranial base and frontal part of the face in patients with mandibular prognathism, Kefalometrijska analiza kranijalne baze i prednjeg dela lica kod osoba sa mandibularnim prognatizmom",
volume = "71",
number = "6",
pages = "534-541",
doi = "10.2298/VSP121212011C"
}

Čutović, T., Jović, N., Stojanović, L., Radojičić, J., Mladenović, I., Matijević, S.,& Kozomara, R.. (2014). A cephalometric analysis of the cranial base and frontal part of the face in patients with mandibular prognathism. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 71(6), 534-541.
https://doi.org/10.2298/VSP121212011C

Čutović T, Jović N, Stojanović L, Radojičić J, Mladenović I, Matijević S, Kozomara R. A cephalometric analysis of the cranial base and frontal part of the face in patients with mandibular prognathism. in Vojnosanitetski pregled. 2014;71(6):534-541.
doi:10.2298/VSP121212011C .

Čutović, Tatjana, Jović, Nebojša, Stojanović, Ljiljana, Radojičić, Julija, Mladenović, Irena, Matijević, Stevo, Kozomara, Ružica, "A cephalometric analysis of the cranial base and frontal part of the face in patients with mandibular prognathism" in Vojnosanitetski pregled, 71, no. 6 (2014):534-541,
https://doi.org/10.2298/VSP121212011C . .

TY  - JOUR
AU  - Mladenović, Irena
AU  - Dodić, Slobodan
AU  - Stošić, Srboljub
AU  - Petrović, Dragan
AU  - Čutović, Tatjana
AU  - Kozomara, Ružica
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1891
AB  - Objective: To investigate temporomandibular disorders (TMD), psychosocial, and occlusal variables in class III orthognathic surgery patients with respect to the control subjects, and to compare psychosocial and occlusal features in class III patients with different Research Diagnostic Criteria for TMD (RDC/TMD) diagnoses. Materials and methods: The study enrolled 44 class III patients referred for orthognathic surgery and 44 individuals without a malocclusion. TMD, depression and somatization were assessed by RDC/TMD. Occlusal analysis included Helkimo's Occlusal Index items, overjet and overbite. Results: In the controls, patients with class III deformities had higher prevalence of myogenic TMD, increased grade of chronic pain, and more occlusal deviations. Within the study group, TMD patients reported higher depression score (P  lt  0.01), myofascial pain was related to higher depression and somatization grades (P  lt  0.01, P  lt  0.05 respectively), and disc displacement showed relation with RCP-ICP slide interferences (P  lt  0.05). Conclusion: With respect to subjects without a malocclusion, TMD in class III dentofacial deformities is similar in prevalence, but differs in clinical appearance. Occlusal, but not psychosocial features deviate from those in the controls. While psychosocial variables accompanied TMD and myofascial pain, increased RCP-ICP slide was related to disc displacement in class III patients.
PB  - Churchill Livingstone, Edinburgh
T2  - Journal of Cranio-Maxillofacial Surgery
T1  - TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects
VL  - 42
IS  - 8
SP  - 1604
EP  - 1609
DO  - 10.1016/j.jcms.2014.04.029
ER  - 

@article{
author = "Mladenović, Irena and Dodić, Slobodan and Stošić, Srboljub and Petrović, Dragan and Čutović, Tatjana and Kozomara, Ružica",
year = "2014",
abstract = "Objective: To investigate temporomandibular disorders (TMD), psychosocial, and occlusal variables in class III orthognathic surgery patients with respect to the control subjects, and to compare psychosocial and occlusal features in class III patients with different Research Diagnostic Criteria for TMD (RDC/TMD) diagnoses. Materials and methods: The study enrolled 44 class III patients referred for orthognathic surgery and 44 individuals without a malocclusion. TMD, depression and somatization were assessed by RDC/TMD. Occlusal analysis included Helkimo's Occlusal Index items, overjet and overbite. Results: In the controls, patients with class III deformities had higher prevalence of myogenic TMD, increased grade of chronic pain, and more occlusal deviations. Within the study group, TMD patients reported higher depression score (P  lt  0.01), myofascial pain was related to higher depression and somatization grades (P  lt  0.01, P  lt  0.05 respectively), and disc displacement showed relation with RCP-ICP slide interferences (P  lt  0.05). Conclusion: With respect to subjects without a malocclusion, TMD in class III dentofacial deformities is similar in prevalence, but differs in clinical appearance. Occlusal, but not psychosocial features deviate from those in the controls. While psychosocial variables accompanied TMD and myofascial pain, increased RCP-ICP slide was related to disc displacement in class III patients.",
publisher = "Churchill Livingstone, Edinburgh",
journal = "Journal of Cranio-Maxillofacial Surgery",
title = "TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects",
volume = "42",
number = "8",
pages = "1604-1609",
doi = "10.1016/j.jcms.2014.04.029"
}

Mladenović, I., Dodić, S., Stošić, S., Petrović, D., Čutović, T.,& Kozomara, R.. (2014). TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects. in Journal of Cranio-Maxillofacial Surgery
Churchill Livingstone, Edinburgh., 42(8), 1604-1609.
https://doi.org/10.1016/j.jcms.2014.04.029

Mladenović I, Dodić S, Stošić S, Petrović D, Čutović T, Kozomara R. TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects. in Journal of Cranio-Maxillofacial Surgery. 2014;42(8):1604-1609.
doi:10.1016/j.jcms.2014.04.029 .

Mladenović, Irena, Dodić, Slobodan, Stošić, Srboljub, Petrović, Dragan, Čutović, Tatjana, Kozomara, Ružica, "TMD in class III patients referred for orthognathic surgery: Psychological and dentition-related aspects" in Journal of Cranio-Maxillofacial Surgery, 42, no. 8 (2014):1604-1609,
https://doi.org/10.1016/j.jcms.2014.04.029 . .