TY  - JOUR
AU  - Stojanović, Nikola
AU  - Krunić, Jelena
AU  - Popović, Branka
AU  - Stojičić, Sonja
AU  - Živković, Slavoljub
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1912
AB  - Introduction Because apical periodontitis is recognizably an infectious disease, elimination or reduction of intracanal bacteria is of utmost importance for optimum treatment outcome. Objective The prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals was studied Also, the effect of endodontic therapy by using intracanal medicaments, calcium hydroxide paste (CH) or gutta-percha points containing calcium hydroxide (CH-GP) or chlorhexidine (CHX-GP) on these microorganisms was assessed by polymerase chain reaction (PCR) assay. Methods Fifty-one patients with chronic apical periodontitis were randomly allocated in one of the following groups according to the intracanal medicament used: CH, CH-GP and CHX-GP group. Bacterial samples were taken upon access (S1), after chemomechanical instrumentation (S2) and after 15-day medication (S3). PCR assay was used to detect the presence of selected bacteria. Results E. faecalis was detected in 49% (25/51) and P. gingivalis in 17.6% (9/51) of the samples. Samples which showed no bacterial presence at S1 were excluded from further analysis. Overall analysis of all 29 samples revealed significant differences between S1 and S2 (p lt 0.001), S2 and S3 (p lt 0.05), and S1 and S3 (p lt 0.001). When distinction was made between the intracanal medications, there was a significant difference in the number of PCR positive samples between S1 and S2, S1 and S3, but not between S2 and S3 samples. Conclusion E. faecalis is more prevalent than P. gingivalis in primary endodontic infection. Intracanal medication in conduction with instrumentation and irrigation efficiently eliminates E. faecalis and P. gingivalis from infected root canals.
AB  - Uvod Budući da je apeksni parodontitis oboljenje koje nastaje usled postojanja infekcije, za postizanje optimalnog ishoda lečenja najznačajnije je uklanjanje bakterija iz kanala korena zuba ili barem smanjenje njihovog broja. Cilj rada Cilj ovog rada je bio da se ispita prevalencija bakterija Enterococcus faecalis i Porphyromonas gingivalis u inficiranim kanalima korena zuba i ustanovi efekat endodontskog lečenja primenom intrakanalnih medikamenata - kalcijum-hidroksidne suspenzije (CH), gutaperka-poena na bazi kalcijum-hidroksida (CH-GP) ili gutaperka-poena na bazi hlorheksidina (CHX-GP) - na ove mikroorganizme metodom lančane reakcije polimerizacije (PCR). Metode rada Istraživanjem je obuhvaćena 51 osoba koja je imala zub s hroničnim apeksnim parodontitisom. Ispitanici su metodom slučajnog uzorka svrstani u tri grupe u zavisnosti od vrste primenjenog intrakanalnog medikamenta (CH, CH-GP i CHX-GP). Bakterijski uzorci iz kanala korena sakupljani su pri inicijalnom ulasku u kanal korena (S1), posle hemomehaničke obrade (S2) i posle petnaestodnevnog lečenja (S3). PCR analiza je korišćena za određivanje prisustva ispitivanih bakterija. Rezultati E. faecalis je izolovan iz 25 (49%) uzoraka, a P. gingivalis iz devet (17,6%). Uzorci u kojima nisu nađene bakterije u S1 fazi isključeni su iz dalje analize. Analiza svih 29 uzoraka je ukazala na statistički značajnu razliku između S1 i S2 uzoraka (p lt 0,001), S2 i S3 (p lt 0,05) i S1 i S3 (p lt 0,001). Kada se uzme u obzir vrsta intrakanalnog medikamenta, statistički značajna razlika u broju PCR-pozitivnih uzoraka zabeležena je između S1 i S2, S1 i S3, ali ne i između S2 i S3. Zaključak U primarnoj endodontskoj infekciji E. faecalis se češće javlja od P. gingivalis. Intrakanalna medikacija zajedno s instrumentacijom i irigacijom efikasno uklanja E. faecalis i P. gingivalis iz inficiranih kanala korena.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study
T1  - Prevalencija bakterija Enterococcus faecalis i Porphyromonas gingivalis u inficiranim kanalima korena zuba i njihova osetljivost na endodontsko lečenje - molekularna studija
VL  - 142
IS  - 9-10
SP  - 535
EP  - 541
DO  - 10.2298/SARH1410535S
ER  - 

@article{
author = "Stojanović, Nikola and Krunić, Jelena and Popović, Branka and Stojičić, Sonja and Živković, Slavoljub",
year = "2014",
abstract = "Introduction Because apical periodontitis is recognizably an infectious disease, elimination or reduction of intracanal bacteria is of utmost importance for optimum treatment outcome. Objective The prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals was studied Also, the effect of endodontic therapy by using intracanal medicaments, calcium hydroxide paste (CH) or gutta-percha points containing calcium hydroxide (CH-GP) or chlorhexidine (CHX-GP) on these microorganisms was assessed by polymerase chain reaction (PCR) assay. Methods Fifty-one patients with chronic apical periodontitis were randomly allocated in one of the following groups according to the intracanal medicament used: CH, CH-GP and CHX-GP group. Bacterial samples were taken upon access (S1), after chemomechanical instrumentation (S2) and after 15-day medication (S3). PCR assay was used to detect the presence of selected bacteria. Results E. faecalis was detected in 49% (25/51) and P. gingivalis in 17.6% (9/51) of the samples. Samples which showed no bacterial presence at S1 were excluded from further analysis. Overall analysis of all 29 samples revealed significant differences between S1 and S2 (p lt 0.001), S2 and S3 (p lt 0.05), and S1 and S3 (p lt 0.001). When distinction was made between the intracanal medications, there was a significant difference in the number of PCR positive samples between S1 and S2, S1 and S3, but not between S2 and S3 samples. Conclusion E. faecalis is more prevalent than P. gingivalis in primary endodontic infection. Intracanal medication in conduction with instrumentation and irrigation efficiently eliminates E. faecalis and P. gingivalis from infected root canals., Uvod Budući da je apeksni parodontitis oboljenje koje nastaje usled postojanja infekcije, za postizanje optimalnog ishoda lečenja najznačajnije je uklanjanje bakterija iz kanala korena zuba ili barem smanjenje njihovog broja. Cilj rada Cilj ovog rada je bio da se ispita prevalencija bakterija Enterococcus faecalis i Porphyromonas gingivalis u inficiranim kanalima korena zuba i ustanovi efekat endodontskog lečenja primenom intrakanalnih medikamenata - kalcijum-hidroksidne suspenzije (CH), gutaperka-poena na bazi kalcijum-hidroksida (CH-GP) ili gutaperka-poena na bazi hlorheksidina (CHX-GP) - na ove mikroorganizme metodom lančane reakcije polimerizacije (PCR). Metode rada Istraživanjem je obuhvaćena 51 osoba koja je imala zub s hroničnim apeksnim parodontitisom. Ispitanici su metodom slučajnog uzorka svrstani u tri grupe u zavisnosti od vrste primenjenog intrakanalnog medikamenta (CH, CH-GP i CHX-GP). Bakterijski uzorci iz kanala korena sakupljani su pri inicijalnom ulasku u kanal korena (S1), posle hemomehaničke obrade (S2) i posle petnaestodnevnog lečenja (S3). PCR analiza je korišćena za određivanje prisustva ispitivanih bakterija. Rezultati E. faecalis je izolovan iz 25 (49%) uzoraka, a P. gingivalis iz devet (17,6%). Uzorci u kojima nisu nađene bakterije u S1 fazi isključeni su iz dalje analize. Analiza svih 29 uzoraka je ukazala na statistički značajnu razliku između S1 i S2 uzoraka (p lt 0,001), S2 i S3 (p lt 0,05) i S1 i S3 (p lt 0,001). Kada se uzme u obzir vrsta intrakanalnog medikamenta, statistički značajna razlika u broju PCR-pozitivnih uzoraka zabeležena je između S1 i S2, S1 i S3, ali ne i između S2 i S3. Zaključak U primarnoj endodontskoj infekciji E. faecalis se češće javlja od P. gingivalis. Intrakanalna medikacija zajedno s instrumentacijom i irigacijom efikasno uklanja E. faecalis i P. gingivalis iz inficiranih kanala korena.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study, Prevalencija bakterija Enterococcus faecalis i Porphyromonas gingivalis u inficiranim kanalima korena zuba i njihova osetljivost na endodontsko lečenje - molekularna studija",
volume = "142",
number = "9-10",
pages = "535-541",
doi = "10.2298/SARH1410535S"
}

Stojanović, N., Krunić, J., Popović, B., Stojičić, S.,& Živković, S.. (2014). Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 142(9-10), 535-541.
https://doi.org/10.2298/SARH1410535S

Stojanović N, Krunić J, Popović B, Stojičić S, Živković S. Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study. in Srpski arhiv za celokupno lekarstvo. 2014;142(9-10):535-541.
doi:10.2298/SARH1410535S .

Stojanović, Nikola, Krunić, Jelena, Popović, Branka, Stojičić, Sonja, Živković, Slavoljub, "Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study" in Srpski arhiv za celokupno lekarstvo, 142, no. 9-10 (2014):535-541,
https://doi.org/10.2298/SARH1410535S . .

TY  - JOUR
AU  - Stojičić, Sonja
AU  - Živković, Slavoljub
AU  - Qian, Wei
AU  - Zhang, Hui
AU  - Haapasalo, Markus
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1586
AB  - Aim: Sodium hypochlorite is the most commonly used endodontic irrigant because of its antimicrobial and tissue-dissolving activity. The aim of this study was to evaluate and compare the effects of concentration, temperature, and agitation on the tissue-dissolving ability of sodium hypochlorite. In addition, a hypochlorite product with added surface active agent was compared with conventional hypochlorite solutions. Methods: Three sodium hypochlorite solutions from two different manufacturers in concentrations of 1%, 2%, 4%, and 5.8% were tested at room temperature, 37 degrees C, and 45 degrees C with and without agitation by ultrasonic and sonic energy and pipetting. Distilled and sterilized tap water was used as controls. Pieces of bovine muscle tissue (68 +/- 3 mg) were placed in 10 mL of each solution for five minutes. In selected samples, agitation was performed for one, two, or four 15-second periods per each minute. The tissue specimens were weighed before and after treatment, and the percentage of weight loss was calculated. The contact angle on dentin of the three solutions at concentrations of 1% and 5.8% was measured. Results: Weight loss (dissolution) of the tissue increased almost linearly with the concentration of sodium hypochlorite. Higher temperatures and agitation considerably enhanced the efficacy of sodium hypochlorite. The effect of agitation on tissue dissolution was greater than that of temperature; continuous agitation resulted in the fastest tissue dissolution. Hypochlorite with added surface active agent had the lowest contact angle on dentin and was most effective in tissue dissolution in all experimental situations. Conclusions: Optimizing the concentration, temperature, flow, and surface tension can improve the tissue-dissolving effectiveness of hypochlorite even 50-fold. (J Endod 2010;36:1558-1562)
PB  - Elsevier Science Inc, New York
T2  - Journal of Endodontics
T1  - Tissue Dissolution by Sodium Hypochlorite: Effect of Concentration, Temperature, Agitation, and Surfactant
VL  - 36
IS  - 9
SP  - 1558
EP  - 1562
DO  - 10.1016/j.joen.2010.06.021
ER  - 

@article{
author = "Stojičić, Sonja and Živković, Slavoljub and Qian, Wei and Zhang, Hui and Haapasalo, Markus",
year = "2010",
abstract = "Aim: Sodium hypochlorite is the most commonly used endodontic irrigant because of its antimicrobial and tissue-dissolving activity. The aim of this study was to evaluate and compare the effects of concentration, temperature, and agitation on the tissue-dissolving ability of sodium hypochlorite. In addition, a hypochlorite product with added surface active agent was compared with conventional hypochlorite solutions. Methods: Three sodium hypochlorite solutions from two different manufacturers in concentrations of 1%, 2%, 4%, and 5.8% were tested at room temperature, 37 degrees C, and 45 degrees C with and without agitation by ultrasonic and sonic energy and pipetting. Distilled and sterilized tap water was used as controls. Pieces of bovine muscle tissue (68 +/- 3 mg) were placed in 10 mL of each solution for five minutes. In selected samples, agitation was performed for one, two, or four 15-second periods per each minute. The tissue specimens were weighed before and after treatment, and the percentage of weight loss was calculated. The contact angle on dentin of the three solutions at concentrations of 1% and 5.8% was measured. Results: Weight loss (dissolution) of the tissue increased almost linearly with the concentration of sodium hypochlorite. Higher temperatures and agitation considerably enhanced the efficacy of sodium hypochlorite. The effect of agitation on tissue dissolution was greater than that of temperature; continuous agitation resulted in the fastest tissue dissolution. Hypochlorite with added surface active agent had the lowest contact angle on dentin and was most effective in tissue dissolution in all experimental situations. Conclusions: Optimizing the concentration, temperature, flow, and surface tension can improve the tissue-dissolving effectiveness of hypochlorite even 50-fold. (J Endod 2010;36:1558-1562)",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Endodontics",
title = "Tissue Dissolution by Sodium Hypochlorite: Effect of Concentration, Temperature, Agitation, and Surfactant",
volume = "36",
number = "9",
pages = "1558-1562",
doi = "10.1016/j.joen.2010.06.021"
}

Stojičić, S., Živković, S., Qian, W., Zhang, H.,& Haapasalo, M.. (2010). Tissue Dissolution by Sodium Hypochlorite: Effect of Concentration, Temperature, Agitation, and Surfactant. in Journal of Endodontics
Elsevier Science Inc, New York., 36(9), 1558-1562.
https://doi.org/10.1016/j.joen.2010.06.021

Stojičić S, Živković S, Qian W, Zhang H, Haapasalo M. Tissue Dissolution by Sodium Hypochlorite: Effect of Concentration, Temperature, Agitation, and Surfactant. in Journal of Endodontics. 2010;36(9):1558-1562.
doi:10.1016/j.joen.2010.06.021 .

Stojičić, Sonja, Živković, Slavoljub, Qian, Wei, Zhang, Hui, Haapasalo, Markus, "Tissue Dissolution by Sodium Hypochlorite: Effect of Concentration, Temperature, Agitation, and Surfactant" in Journal of Endodontics, 36, no. 9 (2010):1558-1562,
https://doi.org/10.1016/j.joen.2010.06.021 . .

TY  - JOUR
AU  - Stojičić, Sonja
AU  - Jevremović, Danimir
AU  - Živković, Slavoljub
PY  - 2009
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1474
AB  - The prognosis of endodontically treated teeth depends not only on the success of the endodontic treatment, but also on the type of reconstruction. The use of fiber-reinforced resin (FRR) posts to restore endodontically treated teeth has gained popularity due to its mechanical and esthetic characteristics as well as properties of modern adhesive systems. The aim of this article was to show a clinical technique to reconstruct endodontically treated teeth with great loss of tooth structure using direct fiber-reinforced post systems and direct composite restorations. The first case was a patient with the fractured right second lower premolar. The tooth was endodontically treated and reconstructed thereafter. After the preparation of the root canal and cementation of a FRR post, particular attention was paid to the incremental and curing techniques adopted to reconstruct coronal part of the tooth. The second case was a patient with the fractured first right lower incisor. This tooth was treated in the same way. Direct composite reconstruction of endodontically treated teeth is an alternative to the prosthodontic therapy and can postpone prosthodontic therapy for a long time.
AB  - Prognoza endodontski lečenog zuba ne zavisi samo od uspešno izvedene endodontske terapije, već i od pravilne restauracije zuba i njegovog vraćanja u funkciju. Kompozitni kočići ojačani vlaknima poslednjih godina dobijaju na popularnosti u rekonstrukciji endodontski lečenih zuba zahvaljujući svojim estetskim i biomehaničkim osobinama, te mogućnosti ostvarivanja adhezivne veze za zub. Cilj ovog rada je da na primerima iz prakse ukaže na mogućnost konzervativne terapije endodontski lečenih zuba s velikim oštećenjima krunice primenom kompozitnih kanalnih kočića. Kod jedne pacijentkinje s frakturom donjeg desnog drugog premolara obavljeno je najpre endodontsko lečenje, a potom je urađena konzervativna restauracija. Posle preparacije prostora za kanalni kočić i njegovog cementiranja, krunični deo zuba je restauriran direktnim kompozitnim ispunom slojevitom tehnikom. Na isti način je lečen i donji desni centralni sekutić druge pacijentkinje. Restauracija devitalizovanih zuba s opsežnim lezijama konzervativnim lečenjem je dobra alternativa protetičkoj restauraciji, koja protetički tretman može odložiti za duži vremenski period.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Reconstruction of endodontically treated teeth after excessive loss of tooth structure: Two case reports
T1  - Mogućnosti rekonstrukcije endodontski lečenih zuba s velikim oštećenjima krunice - dva prikaza iz prakse
VL  - 56
IS  - 1
SP  - 40
EP  - 48
DO  - 10.2298/SGS0901040S
ER  - 

@article{
author = "Stojičić, Sonja and Jevremović, Danimir and Živković, Slavoljub",
year = "2009",
abstract = "The prognosis of endodontically treated teeth depends not only on the success of the endodontic treatment, but also on the type of reconstruction. The use of fiber-reinforced resin (FRR) posts to restore endodontically treated teeth has gained popularity due to its mechanical and esthetic characteristics as well as properties of modern adhesive systems. The aim of this article was to show a clinical technique to reconstruct endodontically treated teeth with great loss of tooth structure using direct fiber-reinforced post systems and direct composite restorations. The first case was a patient with the fractured right second lower premolar. The tooth was endodontically treated and reconstructed thereafter. After the preparation of the root canal and cementation of a FRR post, particular attention was paid to the incremental and curing techniques adopted to reconstruct coronal part of the tooth. The second case was a patient with the fractured first right lower incisor. This tooth was treated in the same way. Direct composite reconstruction of endodontically treated teeth is an alternative to the prosthodontic therapy and can postpone prosthodontic therapy for a long time., Prognoza endodontski lečenog zuba ne zavisi samo od uspešno izvedene endodontske terapije, već i od pravilne restauracije zuba i njegovog vraćanja u funkciju. Kompozitni kočići ojačani vlaknima poslednjih godina dobijaju na popularnosti u rekonstrukciji endodontski lečenih zuba zahvaljujući svojim estetskim i biomehaničkim osobinama, te mogućnosti ostvarivanja adhezivne veze za zub. Cilj ovog rada je da na primerima iz prakse ukaže na mogućnost konzervativne terapije endodontski lečenih zuba s velikim oštećenjima krunice primenom kompozitnih kanalnih kočića. Kod jedne pacijentkinje s frakturom donjeg desnog drugog premolara obavljeno je najpre endodontsko lečenje, a potom je urađena konzervativna restauracija. Posle preparacije prostora za kanalni kočić i njegovog cementiranja, krunični deo zuba je restauriran direktnim kompozitnim ispunom slojevitom tehnikom. Na isti način je lečen i donji desni centralni sekutić druge pacijentkinje. Restauracija devitalizovanih zuba s opsežnim lezijama konzervativnim lečenjem je dobra alternativa protetičkoj restauraciji, koja protetički tretman može odložiti za duži vremenski period.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Reconstruction of endodontically treated teeth after excessive loss of tooth structure: Two case reports, Mogućnosti rekonstrukcije endodontski lečenih zuba s velikim oštećenjima krunice - dva prikaza iz prakse",
volume = "56",
number = "1",
pages = "40-48",
doi = "10.2298/SGS0901040S"
}

Stojičić, S., Jevremović, D.,& Živković, S.. (2009). Reconstruction of endodontically treated teeth after excessive loss of tooth structure: Two case reports. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 56(1), 40-48.
https://doi.org/10.2298/SGS0901040S

Stojičić S, Jevremović D, Živković S. Reconstruction of endodontically treated teeth after excessive loss of tooth structure: Two case reports. in Stomatološki glasnik Srbije. 2009;56(1):40-48.
doi:10.2298/SGS0901040S .

Stojičić, Sonja, Jevremović, Danimir, Živković, Slavoljub, "Reconstruction of endodontically treated teeth after excessive loss of tooth structure: Two case reports" in Stomatološki glasnik Srbije, 56, no. 1 (2009):40-48,
https://doi.org/10.2298/SGS0901040S . .

TY  - THES
AU  - Stojičić, Sonja
PY  - 2008
UR  - https://plus.sr.cobiss.net/opac7/bib/1024035214
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/462
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Uloga centralnih receptora vazopresina u modulaciji kardiovaskularnog odgovora na stres
UR  - https://hdl.handle.net/21.15107/rcub_smile_462
ER  - 

@mastersthesis{
author = "Stojičić, Sonja",
year = "2008",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Uloga centralnih receptora vazopresina u modulaciji kardiovaskularnog odgovora na stres",
url = "https://hdl.handle.net/21.15107/rcub_smile_462"
}

Stojičić, S.. (2008). Uloga centralnih receptora vazopresina u modulaciji kardiovaskularnog odgovora na stres. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_462

Stojičić S. Uloga centralnih receptora vazopresina u modulaciji kardiovaskularnog odgovora na stres. 2008;.
https://hdl.handle.net/21.15107/rcub_smile_462 .

Stojičić, Sonja, "Uloga centralnih receptora vazopresina u modulaciji kardiovaskularnog odgovora na stres" (2008),
https://hdl.handle.net/21.15107/rcub_smile_462 .

TY  - JOUR
AU  - Stojičić, Sonja
AU  - Milutinović-Smiljanić, Sanja
AU  - Sarenac, Olivera
AU  - Milosavljević, S.
AU  - Paton, J. F. R.
AU  - Murphy, David
AU  - Japundžić-Žigon, Nina
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1431
AB  - To investigate the contribution of central vasopressin receptors to blood pressure (BP) and heart rate (HR) response to stress we injected non-peptide selective V-1a (SR49059), V-1b (SSR 149415), V-2 (SR 121463) receptor antagonists, diazepam or vehicle in the lateral cerebral ventricle of conscious freely moving rats stressed by blowing air on their heads for 2 min. Cardiovascular effects of stress were evaluated by analyzing maximum increase of BP and HR (MAX), latency of maximum response (LAT), integral under BP and HR curve (integral), duration of their recovery and spectral parameters of BP and HR indicative of increased sympathetic outflow (LFBP and LF/HFHR). Moreover, the increase of serum corticosterone was measured. Exposure to air-jet stress induced simultaneous increase in BP and HR followed by gradual decline during recovery while LFBP oscillation remained increased as well as serum corticosterone level. Rats pre-treated with vasopressin receptor antagonists were not sedated while diazepam induced sedation that persisted during exposure to stress. V-1a, V-1b and V-2, receptor antagonists applied separately did not modify basal values of cardiovascular parameters but prevented the increase in integral(BP). In addition, V-1b and V-2 receptor antagonists reduced BPMAX whereas V-1a, V-1b antagonist and diazepam reduced HRMAX induced by exposure to air-jet stress. All drugs shortened the recovery period, prevented the increase of LFBP without affecting the increase in serum corticosterone levels. Results indicate that vasopressin receptors located within the central nervous system mediate, in part, the cardiovascular response to air-jet stress without affecting either the neuroendocrine component or inducing sedation. They support the view that the V-1b receptor antagonist may be of potential therapeutic value in reducing arterial pressure induced by stress-related disorders.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Neuropharmacology
T1  - Blockade of central vasopressin receptors reduces the cardiovascular response to acute stress in freely moving rats
VL  - 54
IS  - 5
SP  - 824
EP  - 836
DO  - 10.1016/j.neuropharm.2007.12.013
ER  - 

@article{
author = "Stojičić, Sonja and Milutinović-Smiljanić, Sanja and Sarenac, Olivera and Milosavljević, S. and Paton, J. F. R. and Murphy, David and Japundžić-Žigon, Nina",
year = "2008",
abstract = "To investigate the contribution of central vasopressin receptors to blood pressure (BP) and heart rate (HR) response to stress we injected non-peptide selective V-1a (SR49059), V-1b (SSR 149415), V-2 (SR 121463) receptor antagonists, diazepam or vehicle in the lateral cerebral ventricle of conscious freely moving rats stressed by blowing air on their heads for 2 min. Cardiovascular effects of stress were evaluated by analyzing maximum increase of BP and HR (MAX), latency of maximum response (LAT), integral under BP and HR curve (integral), duration of their recovery and spectral parameters of BP and HR indicative of increased sympathetic outflow (LFBP and LF/HFHR). Moreover, the increase of serum corticosterone was measured. Exposure to air-jet stress induced simultaneous increase in BP and HR followed by gradual decline during recovery while LFBP oscillation remained increased as well as serum corticosterone level. Rats pre-treated with vasopressin receptor antagonists were not sedated while diazepam induced sedation that persisted during exposure to stress. V-1a, V-1b and V-2, receptor antagonists applied separately did not modify basal values of cardiovascular parameters but prevented the increase in integral(BP). In addition, V-1b and V-2 receptor antagonists reduced BPMAX whereas V-1a, V-1b antagonist and diazepam reduced HRMAX induced by exposure to air-jet stress. All drugs shortened the recovery period, prevented the increase of LFBP without affecting the increase in serum corticosterone levels. Results indicate that vasopressin receptors located within the central nervous system mediate, in part, the cardiovascular response to air-jet stress without affecting either the neuroendocrine component or inducing sedation. They support the view that the V-1b receptor antagonist may be of potential therapeutic value in reducing arterial pressure induced by stress-related disorders.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Neuropharmacology",
title = "Blockade of central vasopressin receptors reduces the cardiovascular response to acute stress in freely moving rats",
volume = "54",
number = "5",
pages = "824-836",
doi = "10.1016/j.neuropharm.2007.12.013"
}

Stojičić, S., Milutinović-Smiljanić, S., Sarenac, O., Milosavljević, S., Paton, J. F. R., Murphy, D.,& Japundžić-Žigon, N.. (2008). Blockade of central vasopressin receptors reduces the cardiovascular response to acute stress in freely moving rats. in Neuropharmacology
Pergamon-Elsevier Science Ltd, Oxford., 54(5), 824-836.
https://doi.org/10.1016/j.neuropharm.2007.12.013

Stojičić S, Milutinović-Smiljanić S, Sarenac O, Milosavljević S, Paton JFR, Murphy D, Japundžić-Žigon N. Blockade of central vasopressin receptors reduces the cardiovascular response to acute stress in freely moving rats. in Neuropharmacology. 2008;54(5):824-836.
doi:10.1016/j.neuropharm.2007.12.013 .

Stojičić, Sonja, Milutinović-Smiljanić, Sanja, Sarenac, Olivera, Milosavljević, S., Paton, J. F. R., Murphy, David, Japundžić-Žigon, Nina, "Blockade of central vasopressin receptors reduces the cardiovascular response to acute stress in freely moving rats" in Neuropharmacology, 54, no. 5 (2008):824-836,
https://doi.org/10.1016/j.neuropharm.2007.12.013 . .

TY  - JOUR
AU  - Živković, Slavoljub
AU  - Županjac, Srđan
AU  - Stojičić, Sonja
AU  - Nešković, Jelena
AU  - Manojlović, Dragica
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1312
AB  - The therapy of non-caries cervical lesions is an important problem in restorative dentistry, for the ambiguous aetiology, clinical diagnoses and for the selection of restorative procedure. Aim: The aim of this work was to clinically check the efficiency of non-caries cervical lesions restoration depending on materials used for restorative fillings. Materials and methods: Clinical researches covered 62 teeth of different morphology group at the patients of both gender and of different age. The restoration of gingival lesions, with no previous preparation, was done with composite adhesive system SINGLE BOND/Valux Plus (3M) (30 teeth) and with campomer DYRACT AO (Dentsplay) (32 teeth). The fillings were estimated on the checkups which took place on 3,6 and12 months applying modified criteria according to Ridge and Cvar. Results: The acquired results showed that after 3 to 6 months there were no changes at none of examined parameters and all the fillings got maximal mark A. 12 months latter, in the two cases with composite filling, the marginal adaptation got the mark B (607%). The marginal adaptation at two teeth restored with compomers got the mark B (6.3%) Postoperative sensitiveness phenomenon, marginal discoloration and secondary caries weren’t registered in none of the cases after the observation period of 12 months. Conclusion: For the restoration of non-caries cervical lesions, composite materials with suitable adhesive system and the new generation of compomers could be used.
AB  - Terapija nekarijesnih cervikalnih lezija je značajan problem u restaurativnoj stomatologiji, zbog nejasne etiologije, kliničke dijagnoze ali i izbora restaurativne procedure. Cilj: Cilj ovog rada je bio da se klinički proveri efikasnost restauracija nekarijesnih cervikalnih lezija zuba u zavisnosti od korišćenih materijala za restaurativne ispune. Materijal i metod: Klinička ispitivanja su obuhvatila 62 zuba različitih morfoloških grupa kod pacijenata oba pola i različite starosti. Restauracija gingivalnih lezija, bez prethodne preparacije, urađena je kompozitnim adhezivnim sistemom SINGLE BOND/Valux Plus (3M) (30 zuba) i kompomerom DYRACT AP (Dentsplay) (32 zuba). Ispuni su procenjivani na kontrolnim pregledima posle 3, 6 i 12 meseci primenom modifikovanih kriterijuma po Ridge-u i Cvar-u. Rezultati: Dobijeni rezultati su pokazali da posle 3 i 6 meseci nije bilo promena na ispunima ni kod jednog ispitivanog parametra i svi ispuni su ocenjeni maksimalnom ocenom A. Posle 12 meseci, u dva slučaja ispunjenih kompozitima, ivična adaptacija je ocenjena ocenom B (6,7%). Ivična adaptacija je i u dva zuba restaurisanih kompomerima ocenjena ocenom B (6,3%). Pojava postoperativne osetljivosti, ivične diskoloracije i sekundarnog karijesa nije registovana ni u jednom slučaju posle observacionog perioda od 12 meseci. Zaključak: Za restauraciju nekarijesnih cervikalnih lezija mogu se koristiti kompozitni materijali sa odgovarajućim adhezivnim sistemima i novije generacije kompomera.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Clinical research of cervical non-carious lesion restoration
T1  - Klinička ispitivanja restauracija cervikalnih nekarijesnih lezija
VL  - 53
IS  - 1
SP  - 27
EP  - 34
DO  - 10.2298/SGS0601027Z
ER  - 

@article{
author = "Živković, Slavoljub and Županjac, Srđan and Stojičić, Sonja and Nešković, Jelena and Manojlović, Dragica",
year = "2006",
abstract = "The therapy of non-caries cervical lesions is an important problem in restorative dentistry, for the ambiguous aetiology, clinical diagnoses and for the selection of restorative procedure. Aim: The aim of this work was to clinically check the efficiency of non-caries cervical lesions restoration depending on materials used for restorative fillings. Materials and methods: Clinical researches covered 62 teeth of different morphology group at the patients of both gender and of different age. The restoration of gingival lesions, with no previous preparation, was done with composite adhesive system SINGLE BOND/Valux Plus (3M) (30 teeth) and with campomer DYRACT AO (Dentsplay) (32 teeth). The fillings were estimated on the checkups which took place on 3,6 and12 months applying modified criteria according to Ridge and Cvar. Results: The acquired results showed that after 3 to 6 months there were no changes at none of examined parameters and all the fillings got maximal mark A. 12 months latter, in the two cases with composite filling, the marginal adaptation got the mark B (607%). The marginal adaptation at two teeth restored with compomers got the mark B (6.3%) Postoperative sensitiveness phenomenon, marginal discoloration and secondary caries weren’t registered in none of the cases after the observation period of 12 months. Conclusion: For the restoration of non-caries cervical lesions, composite materials with suitable adhesive system and the new generation of compomers could be used., Terapija nekarijesnih cervikalnih lezija je značajan problem u restaurativnoj stomatologiji, zbog nejasne etiologije, kliničke dijagnoze ali i izbora restaurativne procedure. Cilj: Cilj ovog rada je bio da se klinički proveri efikasnost restauracija nekarijesnih cervikalnih lezija zuba u zavisnosti od korišćenih materijala za restaurativne ispune. Materijal i metod: Klinička ispitivanja su obuhvatila 62 zuba različitih morfoloških grupa kod pacijenata oba pola i različite starosti. Restauracija gingivalnih lezija, bez prethodne preparacije, urađena je kompozitnim adhezivnim sistemom SINGLE BOND/Valux Plus (3M) (30 zuba) i kompomerom DYRACT AP (Dentsplay) (32 zuba). Ispuni su procenjivani na kontrolnim pregledima posle 3, 6 i 12 meseci primenom modifikovanih kriterijuma po Ridge-u i Cvar-u. Rezultati: Dobijeni rezultati su pokazali da posle 3 i 6 meseci nije bilo promena na ispunima ni kod jednog ispitivanog parametra i svi ispuni su ocenjeni maksimalnom ocenom A. Posle 12 meseci, u dva slučaja ispunjenih kompozitima, ivična adaptacija je ocenjena ocenom B (6,7%). Ivična adaptacija je i u dva zuba restaurisanih kompomerima ocenjena ocenom B (6,3%). Pojava postoperativne osetljivosti, ivične diskoloracije i sekundarnog karijesa nije registovana ni u jednom slučaju posle observacionog perioda od 12 meseci. Zaključak: Za restauraciju nekarijesnih cervikalnih lezija mogu se koristiti kompozitni materijali sa odgovarajućim adhezivnim sistemima i novije generacije kompomera.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Clinical research of cervical non-carious lesion restoration, Klinička ispitivanja restauracija cervikalnih nekarijesnih lezija",
volume = "53",
number = "1",
pages = "27-34",
doi = "10.2298/SGS0601027Z"
}

Živković, S., Županjac, S., Stojičić, S., Nešković, J.,& Manojlović, D.. (2006). Clinical research of cervical non-carious lesion restoration. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 53(1), 27-34.
https://doi.org/10.2298/SGS0601027Z

Živković S, Županjac S, Stojičić S, Nešković J, Manojlović D. Clinical research of cervical non-carious lesion restoration. in Stomatološki glasnik Srbije. 2006;53(1):27-34.
doi:10.2298/SGS0601027Z .

Živković, Slavoljub, Županjac, Srđan, Stojičić, Sonja, Nešković, Jelena, Manojlović, Dragica, "Clinical research of cervical non-carious lesion restoration" in Stomatološki glasnik Srbije, 53, no. 1 (2006):27-34,
https://doi.org/10.2298/SGS0601027Z . .

TY  - JOUR
AU  - Stojičić, Sonja
AU  - Milutinović-Smiljanić, Sanja
AU  - Sarenac, Olivera
AU  - Živković, Slavoljub
AU  - Japundžić-Žigon, Nina
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1316
AB  - This study investigates the contribution of central vasopressin receptors in the modulation of systolic arterial pressure (SAP) and heart rate (HR) response to air-jet stress in conscious Wistar rats equipped with a femoral arterial catheter and intracerebroventricular cannula using novel non-peptide and selective vasopressin V, (SR49059) and V-1b (SSR149415) antagonists. The effects of stress on SAP and HR were evaluated by measuring the maximal response to stress, the latency of the maximal response, the duration of the recovery period, and the increase in the low frequency (LF) short-term variability component. Stress induced a parallel and almost immediate increase in both SAP and HR, followed by enhanced LF SAP variability in the recovery period. Pretreatment of rats with V-1a antagonist did not affect the maximal increase or the latency of SAP and HR response to acute stress, but shortened the recovery period of SAP and HR and prevented the increase in LF SAP. The V-1b antagonist reduced the maximal increase in SAP without affecting HR and their latencies, shortened the recovery period of SAP and inhibited the increase in LF SAP variability. These results indicate that both central V-1a and V-1b receptors mediate cardiovascular changes induced by air-jet stress in conscious rats.
PB  - Walter De Gruyter Gmbh, Berlin
T2  - Biomedizinische Technik
T1  - Central vasopressin V-1a and V-1b receptors modulate the cardiovascular response to air-jet stress in conscious rats
VL  - 51
IS  - 4
SP  - 268
EP  - 271
DO  - 10.1515/BMT.2006.053
ER  - 

@article{
author = "Stojičić, Sonja and Milutinović-Smiljanić, Sanja and Sarenac, Olivera and Živković, Slavoljub and Japundžić-Žigon, Nina",
year = "2006",
abstract = "This study investigates the contribution of central vasopressin receptors in the modulation of systolic arterial pressure (SAP) and heart rate (HR) response to air-jet stress in conscious Wistar rats equipped with a femoral arterial catheter and intracerebroventricular cannula using novel non-peptide and selective vasopressin V, (SR49059) and V-1b (SSR149415) antagonists. The effects of stress on SAP and HR were evaluated by measuring the maximal response to stress, the latency of the maximal response, the duration of the recovery period, and the increase in the low frequency (LF) short-term variability component. Stress induced a parallel and almost immediate increase in both SAP and HR, followed by enhanced LF SAP variability in the recovery period. Pretreatment of rats with V-1a antagonist did not affect the maximal increase or the latency of SAP and HR response to acute stress, but shortened the recovery period of SAP and HR and prevented the increase in LF SAP. The V-1b antagonist reduced the maximal increase in SAP without affecting HR and their latencies, shortened the recovery period of SAP and inhibited the increase in LF SAP variability. These results indicate that both central V-1a and V-1b receptors mediate cardiovascular changes induced by air-jet stress in conscious rats.",
publisher = "Walter De Gruyter Gmbh, Berlin",
journal = "Biomedizinische Technik",
title = "Central vasopressin V-1a and V-1b receptors modulate the cardiovascular response to air-jet stress in conscious rats",
volume = "51",
number = "4",
pages = "268-271",
doi = "10.1515/BMT.2006.053"
}

Stojičić, S., Milutinović-Smiljanić, S., Sarenac, O., Živković, S.,& Japundžić-Žigon, N.. (2006). Central vasopressin V-1a and V-1b receptors modulate the cardiovascular response to air-jet stress in conscious rats. in Biomedizinische Technik
Walter De Gruyter Gmbh, Berlin., 51(4), 268-271.
https://doi.org/10.1515/BMT.2006.053

Stojičić S, Milutinović-Smiljanić S, Sarenac O, Živković S, Japundžić-Žigon N. Central vasopressin V-1a and V-1b receptors modulate the cardiovascular response to air-jet stress in conscious rats. in Biomedizinische Technik. 2006;51(4):268-271.
doi:10.1515/BMT.2006.053 .

Stojičić, Sonja, Milutinović-Smiljanić, Sanja, Sarenac, Olivera, Živković, Slavoljub, Japundžić-Žigon, Nina, "Central vasopressin V-1a and V-1b receptors modulate the cardiovascular response to air-jet stress in conscious rats" in Biomedizinische Technik, 51, no. 4 (2006):268-271,
https://doi.org/10.1515/BMT.2006.053 . .