TY  - JOUR
AU  - Vučković, Mila
AU  - Nikolić, Nadja
AU  - Milašin, Jelena
AU  - Đorđević, Vladan
AU  - Milinković, Iva
AU  - Asotić, Jasminka
AU  - Jezdić, Zoran
AU  - Janković, Saša
AU  - Aleksić, Zoran
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2525
AB  - Introduction/Objective. The objective of the study was to investigate whether there are differences in therapeutic effect between initial treatments of chronic periodontitis [scaling and root planning (SRP)] alone and SRP in conjunction with injectable platelet-rich fibrin (I-PRF) application, comparing clinical parameters after three months. Methods. Twenty-four patients with chronic periodontitis who had at least two sites with probing pocket depth (PPD) ≥ 5 mm on contralateral side participated in the study. Using a split-mouth design, the patients were treated with SRP + I-PRF (study group) or SRP only (control group). The clinical parameters, clinical attachment level (CAL), gingival margin level (GML), PPD, bleeding on probing, and plaque index, were recorded on both sides. Results. Compared to baseline, both treatment modalities demonstrated an improvement in investigated clinical parameters. The mean value of CAL was reduced from 1.97 ± 0.75 (0.25–3.31) to 1.07 ± 0.44 (0.12–1.78) in the study group, whereas it decreased from 1.81 ± 0.66 (0.42–2.96) to 1.48 ± 0.55 (0.22–2.30) in the control group. Similarly, the corresponding values for GML and PPD showed statistically significant difference between the groups (p = 0.040 and p = 0.006, respectively). Conclusion. Regardless the limited number of patients in the study, initial periodontal therapy in conjunction with injectable platelet-rich fibrin proved to display significant improvement in all clinical parameters compared to initial periodontal therapy alone.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis
VL  - 148
IS  - 5-6
SP  - 280
EP  - 285
DO  - 10.2298/SARH190925022V
ER  - 

@article{
author = "Vučković, Mila and Nikolić, Nadja and Milašin, Jelena and Đorđević, Vladan and Milinković, Iva and Asotić, Jasminka and Jezdić, Zoran and Janković, Saša and Aleksić, Zoran",
year = "2020",
abstract = "Introduction/Objective. The objective of the study was to investigate whether there are differences in therapeutic effect between initial treatments of chronic periodontitis [scaling and root planning (SRP)] alone and SRP in conjunction with injectable platelet-rich fibrin (I-PRF) application, comparing clinical parameters after three months. Methods. Twenty-four patients with chronic periodontitis who had at least two sites with probing pocket depth (PPD) ≥ 5 mm on contralateral side participated in the study. Using a split-mouth design, the patients were treated with SRP + I-PRF (study group) or SRP only (control group). The clinical parameters, clinical attachment level (CAL), gingival margin level (GML), PPD, bleeding on probing, and plaque index, were recorded on both sides. Results. Compared to baseline, both treatment modalities demonstrated an improvement in investigated clinical parameters. The mean value of CAL was reduced from 1.97 ± 0.75 (0.25–3.31) to 1.07 ± 0.44 (0.12–1.78) in the study group, whereas it decreased from 1.81 ± 0.66 (0.42–2.96) to 1.48 ± 0.55 (0.22–2.30) in the control group. Similarly, the corresponding values for GML and PPD showed statistically significant difference between the groups (p = 0.040 and p = 0.006, respectively). Conclusion. Regardless the limited number of patients in the study, initial periodontal therapy in conjunction with injectable platelet-rich fibrin proved to display significant improvement in all clinical parameters compared to initial periodontal therapy alone.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis",
volume = "148",
number = "5-6",
pages = "280-285",
doi = "10.2298/SARH190925022V"
}

Vučković, M., Nikolić, N., Milašin, J., Đorđević, V., Milinković, I., Asotić, J., Jezdić, Z., Janković, S.,& Aleksić, Z.. (2020). The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 148(5-6), 280-285.
https://doi.org/10.2298/SARH190925022V

Vučković M, Nikolić N, Milašin J, Đorđević V, Milinković I, Asotić J, Jezdić Z, Janković S, Aleksić Z. The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis. in Srpski arhiv za celokupno lekarstvo. 2020;148(5-6):280-285.
doi:10.2298/SARH190925022V .

Vučković, Mila, Nikolić, Nadja, Milašin, Jelena, Đorđević, Vladan, Milinković, Iva, Asotić, Jasminka, Jezdić, Zoran, Janković, Saša, Aleksić, Zoran, "The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis" in Srpski arhiv za celokupno lekarstvo, 148, no. 5-6 (2020):280-285,
https://doi.org/10.2298/SARH190925022V . .

TY  - JOUR
AU  - Đorđević, Vladan
AU  - Vučković, Mila
AU  - Stefanović, Vesna
AU  - Nikolić-Jakoba, Nataša
AU  - Đokić, Gorica
AU  - Stašević-Karličić, Ivana
AU  - Todorović, Ljubomir
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2440
AB  - Background/Aim. Many studies on oral health of psychiatric inpatients reported schizophrenia as the most common psychiatric disorder among their sample population. The available evidence suggests the higher prevalence and severity of periodontal disease among the psychiatric inpatients. The aim of this study was to evaluate periodontal health among the inpatients with schizophrenia and to consider possible risk factors for their current periodontal diseases. Methods. This cross-sectional study comprised 190 inpatients with schizophrenia at the Clinic for Psychiatric Disorders "Dr Laza Lazarević" in Belgrade, and 190 mentally healthy patients at the Clinic for Periodontology and Oral Medicine, Faculty of Dental Medicine, University in Belgrade. The Community Periodontal Index for Treatment Needs (CPITN) and sociodemographic characteristics were registered in both groups as well as the characteristics of the primary disease among the inpatients with schizophrenia. Results. The patients in the study group had significantly higher scores of the CPITN (2.24 ± 0.98) than the patients in the control group (1.21 ± 1.10). Most of the patients in the study group had supra, or subgingival calculi (46.8%), in contrast to the control group patients, who had in most cases gingival bleeding (45.8%). The periodontal pockets where detected in 35.8% of schizophrenic inpatients. The linear regression analysis showed that the gender and age were statistically significant predictors of the CPITN value among the inpatients with schizophrenia. Conclusion. The results of this study generally indicate the need for continuous research of psychiatric patients' oral health, in order to determine the modes of its improvement. Similar studies should elucidate significance of psychiatric patients' periodontal health and sensitize psychiatrists and psychiatric nurses to the oral problems of their patients.
AB  - Uvod/Cilj. Mnogobrojna istraživanja oralnog zdravlju hospitalizovanih psihijatrijskih bolesnika pokazala su da je shizofrenija najčešći psihijatrijski poremećaj među njima. Dostupni podaci ukazuju na veliku prevalenciju i težinu periodontopatije kod bolesnika sa psihijatrijskim poremećajima. Cilj ove studije bio je da se proceni periodontalno zdravlje hospitalizovanih osoba sa shizofrenijom, kao i da se ukaže na moguće faktore rizika od oboljenja potpornog aparata zuba tih bolesnika. Metode. Studijom preseka obuhvaćeno je 190 osoba sa shizofrenijom, hospitalizovanih u Klinici za psihijatrijske bolesti "Dr Laza Lazarević" u Beogradu i 190 mentalno zdravih osoba, pacijenata Klinike za parodontologiju i oralnu medicinu Stomatološkog fakultet, Univerziteta u Beogradu. U obe grupe ispitanika registrovane su vrednosti Zajednički periodontni indeks potreba tretmana - Community Periodontal Index for Treatment Needs (CPITN), kao i sociodemografska obeležja, dok su karakteristike primarne bolesti beležene u studijskoj grupi. Rezultati. Ispitanici studijske grupe su imali znatno veće vrednosti CPITN (2,24 ± 0,98) u odnosu na ispitanike kontrolne grupe (1,21 ± 1,10). Kod većine ispitanika studijske grupe registrovano je prisustvo supra i subgingivalnog kamenca (46,8%), za razliku od ispitanika kontrolne grupe koji su češće imali gingivalno krvarenje (45,8%). Periodontalni džepovi su registrovani kod 35,8% hospitalizovanih osoba sa shizofrenijom. Linearna regresiona analiza pokazala je da su pol i starost ispitanika bili statistički značajni prediktori vrednosti CPITN hospitalizovanih osoba sa shizofrenijom. Zaključak. Rezultati ovog istraživanja ukazuju na postojanje potrebe za kontinuiranim istraživanjem stanja oralnog zdravlja psihijatrijskih bolesnika, kako bi se odredili načini za njegovo unapređenje. Slične studije bi trebalo da razjasne značaj peridodontalnog zdravlja psihijatrijskih bolesnika, kako bi se psihijatrima i medicinskim sestrama ukazalo na postojanje problema oralnog zdravlja njihovih bolesnika.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Assessment of periodontal health among the inpatients with schizophrenia
T1  - Procena periodontalnog zdravlja hospitalizovanih bolesnika sa shizofrenijom
VL  - 76
IS  - 11
SP  - 1139
EP  - 1146
DO  - 10.2298/VSP170929018D
ER  - 

@article{
author = "Đorđević, Vladan and Vučković, Mila and Stefanović, Vesna and Nikolić-Jakoba, Nataša and Đokić, Gorica and Stašević-Karličić, Ivana and Todorović, Ljubomir",
year = "2019",
abstract = "Background/Aim. Many studies on oral health of psychiatric inpatients reported schizophrenia as the most common psychiatric disorder among their sample population. The available evidence suggests the higher prevalence and severity of periodontal disease among the psychiatric inpatients. The aim of this study was to evaluate periodontal health among the inpatients with schizophrenia and to consider possible risk factors for their current periodontal diseases. Methods. This cross-sectional study comprised 190 inpatients with schizophrenia at the Clinic for Psychiatric Disorders "Dr Laza Lazarević" in Belgrade, and 190 mentally healthy patients at the Clinic for Periodontology and Oral Medicine, Faculty of Dental Medicine, University in Belgrade. The Community Periodontal Index for Treatment Needs (CPITN) and sociodemographic characteristics were registered in both groups as well as the characteristics of the primary disease among the inpatients with schizophrenia. Results. The patients in the study group had significantly higher scores of the CPITN (2.24 ± 0.98) than the patients in the control group (1.21 ± 1.10). Most of the patients in the study group had supra, or subgingival calculi (46.8%), in contrast to the control group patients, who had in most cases gingival bleeding (45.8%). The periodontal pockets where detected in 35.8% of schizophrenic inpatients. The linear regression analysis showed that the gender and age were statistically significant predictors of the CPITN value among the inpatients with schizophrenia. Conclusion. The results of this study generally indicate the need for continuous research of psychiatric patients' oral health, in order to determine the modes of its improvement. Similar studies should elucidate significance of psychiatric patients' periodontal health and sensitize psychiatrists and psychiatric nurses to the oral problems of their patients., Uvod/Cilj. Mnogobrojna istraživanja oralnog zdravlju hospitalizovanih psihijatrijskih bolesnika pokazala su da je shizofrenija najčešći psihijatrijski poremećaj među njima. Dostupni podaci ukazuju na veliku prevalenciju i težinu periodontopatije kod bolesnika sa psihijatrijskim poremećajima. Cilj ove studije bio je da se proceni periodontalno zdravlje hospitalizovanih osoba sa shizofrenijom, kao i da se ukaže na moguće faktore rizika od oboljenja potpornog aparata zuba tih bolesnika. Metode. Studijom preseka obuhvaćeno je 190 osoba sa shizofrenijom, hospitalizovanih u Klinici za psihijatrijske bolesti "Dr Laza Lazarević" u Beogradu i 190 mentalno zdravih osoba, pacijenata Klinike za parodontologiju i oralnu medicinu Stomatološkog fakultet, Univerziteta u Beogradu. U obe grupe ispitanika registrovane su vrednosti Zajednički periodontni indeks potreba tretmana - Community Periodontal Index for Treatment Needs (CPITN), kao i sociodemografska obeležja, dok su karakteristike primarne bolesti beležene u studijskoj grupi. Rezultati. Ispitanici studijske grupe su imali znatno veće vrednosti CPITN (2,24 ± 0,98) u odnosu na ispitanike kontrolne grupe (1,21 ± 1,10). Kod većine ispitanika studijske grupe registrovano je prisustvo supra i subgingivalnog kamenca (46,8%), za razliku od ispitanika kontrolne grupe koji su češće imali gingivalno krvarenje (45,8%). Periodontalni džepovi su registrovani kod 35,8% hospitalizovanih osoba sa shizofrenijom. Linearna regresiona analiza pokazala je da su pol i starost ispitanika bili statistički značajni prediktori vrednosti CPITN hospitalizovanih osoba sa shizofrenijom. Zaključak. Rezultati ovog istraživanja ukazuju na postojanje potrebe za kontinuiranim istraživanjem stanja oralnog zdravlja psihijatrijskih bolesnika, kako bi se odredili načini za njegovo unapređenje. Slične studije bi trebalo da razjasne značaj peridodontalnog zdravlja psihijatrijskih bolesnika, kako bi se psihijatrima i medicinskim sestrama ukazalo na postojanje problema oralnog zdravlja njihovih bolesnika.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Assessment of periodontal health among the inpatients with schizophrenia, Procena periodontalnog zdravlja hospitalizovanih bolesnika sa shizofrenijom",
volume = "76",
number = "11",
pages = "1139-1146",
doi = "10.2298/VSP170929018D"
}

Đorđević, V., Vučković, M., Stefanović, V., Nikolić-Jakoba, N., Đokić, G., Stašević-Karličić, I.,& Todorović, L.. (2019). Assessment of periodontal health among the inpatients with schizophrenia. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(11), 1139-1146.
https://doi.org/10.2298/VSP170929018D

Đorđević V, Vučković M, Stefanović V, Nikolić-Jakoba N, Đokić G, Stašević-Karličić I, Todorović L. Assessment of periodontal health among the inpatients with schizophrenia. in Vojnosanitetski pregled. 2019;76(11):1139-1146.
doi:10.2298/VSP170929018D .

Đorđević, Vladan, Vučković, Mila, Stefanović, Vesna, Nikolić-Jakoba, Nataša, Đokić, Gorica, Stašević-Karličić, Ivana, Todorović, Ljubomir, "Assessment of periodontal health among the inpatients with schizophrenia" in Vojnosanitetski pregled, 76, no. 11 (2019):1139-1146,
https://doi.org/10.2298/VSP170929018D . .

TY  - JOUR
AU  - Kadović, Jana
AU  - Novaković, Nada
AU  - Vučković, Mila
AU  - Đorđević, Vladan
AU  - Petrović, Vanja
AU  - Stojčev-Stajčić, Ljiljana
AU  - Čakić, Saša
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2447
AB  - Background/Aim. Knowledge of numerous variations in anatomical features of furcation area is a prerequisite for the achievement of more predictable results in the therapy of multi-rooted teeth with furcation involvement (FI). The aim of the study was to evaluate the morphological characteristics of extracted molars of adult population in Belgrade, Serbia. Methods. In total, 468 extracted first and second molars, both mandibular and maxillary, were measured. The values of root trunk lengths and root lengths, diameter of furcation entrances (FE), distance between the roots and depth of root concavity were analysed. Results. The maxillary first molars had significantly higher root trunk lengths values than the second molars. As for the mandibular molars, FE was smaller than 1 mm. The distance between the roots was more than 2 mm at the third level of measurement. Conclusion. The buccal FE of maxillary molars was the lowest. The root concavity of the second mandibular molars was higher from the lingual aspect.
AB  - Uvod/Cilj. Poznavanje mnogobrojnih varijacija anatomskih karakteristika furkacija (furkacionih regija) je preduslov za postizanje predvidivih rezultata terapije furkacionih defekata višekorenih zuba. Cilj ovog istraživanja je bio procena morfološke karakteristike izvađenih zuba adultne populacije u Beogradu. Metode. Merenja su vršena na ukupno 468 izvađenih prvih i drugih molara i gornje i donje vilice. Analizirane su izmerene vrednosti dužine korenskog stabla i dužine korenova, prečnik ulaza u furkaciju, odstojanje između korenova i dubina korenskog konkaviteta. Rezultati. Prvi gornji molari su imali signifikantno veće vrednosti dužine korenskog stabla od drugih gornjih molara. Kod donjih molara, prečnik ulaska u furkaciju bio je manji od 1 mm. Na trećem nivou merenja, odstojanje između korenova imalo je vrednost veću od 2 mm. Zaključak. Prečnik ulaska u furkaciju sa bukalne strane gornjih molara bio je najmanji. Dubina korenskog konkaviteta drugih donjih molara bila je veća sa lingvalne strane.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study
T1  - Anatomske karakteristike furkacija i korenova višekorenih zuba - epidemiološka studija
VL  - 76
IS  - 8
SP  - 761
EP  - 771
DO  - 10.2298/VSP170308149K
ER  - 

@article{
author = "Kadović, Jana and Novaković, Nada and Vučković, Mila and Đorđević, Vladan and Petrović, Vanja and Stojčev-Stajčić, Ljiljana and Čakić, Saša",
year = "2019",
abstract = "Background/Aim. Knowledge of numerous variations in anatomical features of furcation area is a prerequisite for the achievement of more predictable results in the therapy of multi-rooted teeth with furcation involvement (FI). The aim of the study was to evaluate the morphological characteristics of extracted molars of adult population in Belgrade, Serbia. Methods. In total, 468 extracted first and second molars, both mandibular and maxillary, were measured. The values of root trunk lengths and root lengths, diameter of furcation entrances (FE), distance between the roots and depth of root concavity were analysed. Results. The maxillary first molars had significantly higher root trunk lengths values than the second molars. As for the mandibular molars, FE was smaller than 1 mm. The distance between the roots was more than 2 mm at the third level of measurement. Conclusion. The buccal FE of maxillary molars was the lowest. The root concavity of the second mandibular molars was higher from the lingual aspect., Uvod/Cilj. Poznavanje mnogobrojnih varijacija anatomskih karakteristika furkacija (furkacionih regija) je preduslov za postizanje predvidivih rezultata terapije furkacionih defekata višekorenih zuba. Cilj ovog istraživanja je bio procena morfološke karakteristike izvađenih zuba adultne populacije u Beogradu. Metode. Merenja su vršena na ukupno 468 izvađenih prvih i drugih molara i gornje i donje vilice. Analizirane su izmerene vrednosti dužine korenskog stabla i dužine korenova, prečnik ulaza u furkaciju, odstojanje između korenova i dubina korenskog konkaviteta. Rezultati. Prvi gornji molari su imali signifikantno veće vrednosti dužine korenskog stabla od drugih gornjih molara. Kod donjih molara, prečnik ulaska u furkaciju bio je manji od 1 mm. Na trećem nivou merenja, odstojanje između korenova imalo je vrednost veću od 2 mm. Zaključak. Prečnik ulaska u furkaciju sa bukalne strane gornjih molara bio je najmanji. Dubina korenskog konkaviteta drugih donjih molara bila je veća sa lingvalne strane.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study, Anatomske karakteristike furkacija i korenova višekorenih zuba - epidemiološka studija",
volume = "76",
number = "8",
pages = "761-771",
doi = "10.2298/VSP170308149K"
}

Kadović, J., Novaković, N., Vučković, M., Đorđević, V., Petrović, V., Stojčev-Stajčić, L.,& Čakić, S.. (2019). Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(8), 761-771.
https://doi.org/10.2298/VSP170308149K

Kadović J, Novaković N, Vučković M, Đorđević V, Petrović V, Stojčev-Stajčić L, Čakić S. Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study. in Vojnosanitetski pregled. 2019;76(8):761-771.
doi:10.2298/VSP170308149K .

Kadović, Jana, Novaković, Nada, Vučković, Mila, Đorđević, Vladan, Petrović, Vanja, Stojčev-Stajčić, Ljiljana, Čakić, Saša, "Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study" in Vojnosanitetski pregled, 76, no. 8 (2019):761-771,
https://doi.org/10.2298/VSP170308149K . .

TY  - JOUR
AU  - Đorđević, Vladan
AU  - Vučković, Mila
AU  - Joksimović, Ena
AU  - Asotić, Amina
AU  - Stašević, Milena
AU  - Asotić, Jasminka
AU  - Petrović, Vanja
AU  - Stašević-Karličić, Ivana
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2429
AB  - Introduction Patients with schizophrenia are likely to constitute a high-risk group of individuals with respect to prevalence of oral diseases and they require special attention. Factors like nature of psychiatric disorders, length of stay and oral-side effects of psychotropic medications have been noted as contributors to poor oral health among institutionalized chronic psychiatric patients. Methods This cross-sectional study comprised 190 inpatients with schizophrenia at the Dr Laza Lazarevic Clinic for Mental Disorders in Belgrade, and 190 mentally healthy patients at the Clinic for Periodontology and Oral Medicine, School of Dental Medicine, University of Belgrade. A questionnaire was designed for the purpose of this research with the aim of recording information on demographic data (age and sex), unhealthy habits (tobacco smoking, alcohol consumption and drug abuse), and data about the existence of any oral symptom and/or sings related to oral soft tissue pathology. All participants were subjected to targeted clinical examinations. Results All study group patients were receiving psychotropic medications (mean number 4.18 ± 1.14; from 1 to 7 medications). The study group patients had a total of 272 symptoms and 121 signs of oral disorders; which was almost four times higher for symptoms and even nine times higher for signs of oral disorders than in the control group. Conclusion Schizophrenia as a mental disorder does not directly affect the condition of oral health of this group of psychiatric patients, but indirectly - reducing their motivation and awareness of the importance of oral health, which is particularly emphasized in hospital conditions.
AB  - Uvod Hospitalizovani bolesnici sa shizofrenijom mogu da predstavljaju visoko rizičnu grupu osoba sa aspekta prevalencije oralnih oboljenja, te zahtevaju posebnu pažnju. Faktori poput prirode psihijatrijske bolesti, dužine hospitalizacije i neželjenih efekata psihotropnih medikamenata utiču na loše oralno zdravlje hospitalizovanih hroničnih psihijatrijskih bolesnika. Metode Ova studija preseka obuhvatila je 190 bolesnika sa shizofrenijom hospitalizovanih u Klinici za psihijatrijske bolesti "Dr Laza Lazarević" u Beogradu i 190 mentalno zdravih bolesnika Klinike za paradontologiju i oralnu medicinu Stomatološkog fakulteta Univerziteta u Beogradu. U svrhu ovog istraživanja dizajniran je upitnik sa ciljem beleženja demografskih podataka (starost i pol), loših navika (pušenje duvana, konzumiranje alkohola i zloupotreba droga) i podataka o postojanju bilo kojeg oralnog simptoma i/ili znaka koji se odnosi na patologiju mekih tkiva usne duplje. Svi učesnici bili su podvrgnuti ciljanim kliničkim pregledima. Rezultati Svi bolesnici iz studijske grupe primali su psihotropne lekove (srednja vrednost 4,18 ± 1,14, od jednog do sedam lekova). Bolesnici studijske grupe imali su ukupno 272 oralna simptoma i 121 znak oralnih oboljenja, što je skoro četiri puta više za oralne simptome, a čak i devet puta više za znake oralnih poremećaja nego u kontrolnoj grupi. Zaključak Shizofrenija kao mentalni poremećaj ne utiče direktno na stanje oralnog zdravlja ove grupe psihijatrijskih bolesnika, već indirektno - smanjujući im motivaciju i svest o značaju oralnog zdravlja, posebno u bolničkim uslovima.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia
T1  - Procena simptoma i znakova oralnih mekotkivnih poremećaja kod hospitalizovanih bolesnika sa shizofrenijom
VL  - 147
IS  - 5-6
SP  - 276
EP  - 280
DO  - 10.2298/SARH190311042D
ER  - 

@article{
author = "Đorđević, Vladan and Vučković, Mila and Joksimović, Ena and Asotić, Amina and Stašević, Milena and Asotić, Jasminka and Petrović, Vanja and Stašević-Karličić, Ivana",
year = "2019",
abstract = "Introduction Patients with schizophrenia are likely to constitute a high-risk group of individuals with respect to prevalence of oral diseases and they require special attention. Factors like nature of psychiatric disorders, length of stay and oral-side effects of psychotropic medications have been noted as contributors to poor oral health among institutionalized chronic psychiatric patients. Methods This cross-sectional study comprised 190 inpatients with schizophrenia at the Dr Laza Lazarevic Clinic for Mental Disorders in Belgrade, and 190 mentally healthy patients at the Clinic for Periodontology and Oral Medicine, School of Dental Medicine, University of Belgrade. A questionnaire was designed for the purpose of this research with the aim of recording information on demographic data (age and sex), unhealthy habits (tobacco smoking, alcohol consumption and drug abuse), and data about the existence of any oral symptom and/or sings related to oral soft tissue pathology. All participants were subjected to targeted clinical examinations. Results All study group patients were receiving psychotropic medications (mean number 4.18 ± 1.14; from 1 to 7 medications). The study group patients had a total of 272 symptoms and 121 signs of oral disorders; which was almost four times higher for symptoms and even nine times higher for signs of oral disorders than in the control group. Conclusion Schizophrenia as a mental disorder does not directly affect the condition of oral health of this group of psychiatric patients, but indirectly - reducing their motivation and awareness of the importance of oral health, which is particularly emphasized in hospital conditions., Uvod Hospitalizovani bolesnici sa shizofrenijom mogu da predstavljaju visoko rizičnu grupu osoba sa aspekta prevalencije oralnih oboljenja, te zahtevaju posebnu pažnju. Faktori poput prirode psihijatrijske bolesti, dužine hospitalizacije i neželjenih efekata psihotropnih medikamenata utiču na loše oralno zdravlje hospitalizovanih hroničnih psihijatrijskih bolesnika. Metode Ova studija preseka obuhvatila je 190 bolesnika sa shizofrenijom hospitalizovanih u Klinici za psihijatrijske bolesti "Dr Laza Lazarević" u Beogradu i 190 mentalno zdravih bolesnika Klinike za paradontologiju i oralnu medicinu Stomatološkog fakulteta Univerziteta u Beogradu. U svrhu ovog istraživanja dizajniran je upitnik sa ciljem beleženja demografskih podataka (starost i pol), loših navika (pušenje duvana, konzumiranje alkohola i zloupotreba droga) i podataka o postojanju bilo kojeg oralnog simptoma i/ili znaka koji se odnosi na patologiju mekih tkiva usne duplje. Svi učesnici bili su podvrgnuti ciljanim kliničkim pregledima. Rezultati Svi bolesnici iz studijske grupe primali su psihotropne lekove (srednja vrednost 4,18 ± 1,14, od jednog do sedam lekova). Bolesnici studijske grupe imali su ukupno 272 oralna simptoma i 121 znak oralnih oboljenja, što je skoro četiri puta više za oralne simptome, a čak i devet puta više za znake oralnih poremećaja nego u kontrolnoj grupi. Zaključak Shizofrenija kao mentalni poremećaj ne utiče direktno na stanje oralnog zdravlja ove grupe psihijatrijskih bolesnika, već indirektno - smanjujući im motivaciju i svest o značaju oralnog zdravlja, posebno u bolničkim uslovima.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia, Procena simptoma i znakova oralnih mekotkivnih poremećaja kod hospitalizovanih bolesnika sa shizofrenijom",
volume = "147",
number = "5-6",
pages = "276-280",
doi = "10.2298/SARH190311042D"
}

Đorđević, V., Vučković, M., Joksimović, E., Asotić, A., Stašević, M., Asotić, J., Petrović, V.,& Stašević-Karličić, I.. (2019). Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 147(5-6), 276-280.
https://doi.org/10.2298/SARH190311042D

Đorđević V, Vučković M, Joksimović E, Asotić A, Stašević M, Asotić J, Petrović V, Stašević-Karličić I. Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia. in Srpski arhiv za celokupno lekarstvo. 2019;147(5-6):276-280.
doi:10.2298/SARH190311042D .

Đorđević, Vladan, Vučković, Mila, Joksimović, Ena, Asotić, Amina, Stašević, Milena, Asotić, Jasminka, Petrović, Vanja, Stašević-Karličić, Ivana, "Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia" in Srpski arhiv za celokupno lekarstvo, 147, no. 5-6 (2019):276-280,
https://doi.org/10.2298/SARH190311042D . .

TY  - JOUR
AU  - Đorđević, Vladan
AU  - Vučković, Mila
AU  - Miličić, Biljana
AU  - Stefanović, Vesna
AU  - Đukić-Dejanović, Slavica
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2074
AB  - Background/Aim. It is considered that over 450 million people worldwide suffer from some form of mental disorder. Previous studies in other countries have shown that schizophrenia is among the most frequent. Oral health is significant for general health and should not be separated from mental health. Studies in other countries have shown an increased incidence of carious and extracted teeth, and less incidence of filled teeth in this group of psychiatric patients. The aim of this study was to establish condition of the existing teeth, to determine the prevalence of caries and to consider possible risk factors that contribute to the current oral health status of hospitalized patients with schizophrenia. Methods. The study comprised 190 patients with schizophrenia, hospitalized at the Clinic for Psychiatric Disorders 'Dr. Laza Lazarević' in Belgrade, and 190 mentally healthy patients at the Clinic for Periodontology and Oral Medicine, Faculty of Dental Medicine in Belgrade. The decayed, missing, filled (DMF) index, sociodemographic and economic characteristics were registered in both groups, as well as characteristics of the primary disease of hospitalized patients with schizophrenia. Results. The value of DMF index (representing the sum of carious, extracted and filled teeth), in the hospitalized patients with schizophrenia was 18.57 ± 7.07 and 12.47 ± 5.64 in the healthy group (p = 0.000). The structure of the DMF index in the study group showed that caries and extracted teeth dominated with 88.1%; in the control group, filled teeth dominated with 55.6%, which was a statistically significant difference for all the three observed variables. Conclusion. Hospitalized patients with schizophrenia had twice as many caries and extracted teeth, and five time less filled teeth than healthy people. The patient's age and taking antiparkinsonics were established as predictors of the increased DMF index in hospitalized patients with schizophrenia.
AB  - Uvod/Cilj. Smatra se da preko 450 miliona ljudi širom sveta pati od nekog oblika mentalnog poremećaja, a istraživanja sprovedena u drugim zemljama pokazala su da je shizofrenija među najzastupljenijima. Oralno zdravlje zauzima značajno mesto u celokupnom zdravlju čoveka i ne treba ga razdvajati od mentalnog zdravlja. Istraživanja sprovedena u drugim zemljama pokazala su povećanu zastupljenost karijesnih i izvađenih zuba, a manje plombiranih zuba kod ove grupe psihijatrijskih bolesnika. Cilj studije bio je da se istraži stanje prisutnih zuba, odredi prevalencija karijesa i ispitaju mogući faktori rizika koji doprinose postojećem stanju oralnog zdravlja kod bolesnika hospitalizovanih zbog shizofrenije. Metode. U istraživanju je učestvovalo 190 bolesnika sa shizofrenijom, hospitalizovanih na Klinici za psihijatrijske bolesti 'Dr Laza Lazarević' u Beogradu i 190 mentalno zdravih ispitanika, pacijenata Klinike za parodontologiju i oralnu medicinu Stomatološkog fakulteta u Beogradu. Ispitanicima obe grupe registrovane su vrednosti KEP indeksa, sociodemografske i ekonomske karakteristike, a bolesnicima hospitalizovanim zbog shizofrenije i karakteristike primarne bolesti. Rezultati. Vrednost KEP indeksa kod bolesnika hospitalizovanih zbog shizofrenije iznosila je 18,57 ± 7,07, a kod zdravih osoba 12,47 ± 5,64 (p = 0,000). U strukturi indeksa koji pokazuje zbir brojeva karioznih, ekstrahovanih i plombiranih zuba (KEP) kod bolesnika sa shizofrenijom, dominirali su karijesni i ekstrahovani zubi - 88,1%, a u kontrolnoj grupi plombirani zubi - 55,6%, što je bila statistički značajna razlika za sve tri posmatrane varijable. Zaključak. Bolesnici hospitalizovani zbog shizofrenije imali su dvostruko više karijesnih i izvađenih zuba, a pet puta manje plombiranih zuba od zdravih osoba. Kao prediktori povećanog KEP indeksa kod bolesnika hospitalizovanih zbog shizofrenije ustanovljeni su starost ispitanika i korišćenje antiparkinsonika.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Prevalence of dental caries in hospitalized patients with schizophrenia
T1  - Prevalencija karijesa kod bolesnika hospitalizovanih zbog shizofrenije
VL  - 73
IS  - 12
SP  - 1102
EP  - 1108
DO  - 10.2298/VSP150917111D
ER  - 

@article{
author = "Đorđević, Vladan and Vučković, Mila and Miličić, Biljana and Stefanović, Vesna and Đukić-Dejanović, Slavica",
year = "2016",
abstract = "Background/Aim. It is considered that over 450 million people worldwide suffer from some form of mental disorder. Previous studies in other countries have shown that schizophrenia is among the most frequent. Oral health is significant for general health and should not be separated from mental health. Studies in other countries have shown an increased incidence of carious and extracted teeth, and less incidence of filled teeth in this group of psychiatric patients. The aim of this study was to establish condition of the existing teeth, to determine the prevalence of caries and to consider possible risk factors that contribute to the current oral health status of hospitalized patients with schizophrenia. Methods. The study comprised 190 patients with schizophrenia, hospitalized at the Clinic for Psychiatric Disorders 'Dr. Laza Lazarević' in Belgrade, and 190 mentally healthy patients at the Clinic for Periodontology and Oral Medicine, Faculty of Dental Medicine in Belgrade. The decayed, missing, filled (DMF) index, sociodemographic and economic characteristics were registered in both groups, as well as characteristics of the primary disease of hospitalized patients with schizophrenia. Results. The value of DMF index (representing the sum of carious, extracted and filled teeth), in the hospitalized patients with schizophrenia was 18.57 ± 7.07 and 12.47 ± 5.64 in the healthy group (p = 0.000). The structure of the DMF index in the study group showed that caries and extracted teeth dominated with 88.1%; in the control group, filled teeth dominated with 55.6%, which was a statistically significant difference for all the three observed variables. Conclusion. Hospitalized patients with schizophrenia had twice as many caries and extracted teeth, and five time less filled teeth than healthy people. The patient's age and taking antiparkinsonics were established as predictors of the increased DMF index in hospitalized patients with schizophrenia., Uvod/Cilj. Smatra se da preko 450 miliona ljudi širom sveta pati od nekog oblika mentalnog poremećaja, a istraživanja sprovedena u drugim zemljama pokazala su da je shizofrenija među najzastupljenijima. Oralno zdravlje zauzima značajno mesto u celokupnom zdravlju čoveka i ne treba ga razdvajati od mentalnog zdravlja. Istraživanja sprovedena u drugim zemljama pokazala su povećanu zastupljenost karijesnih i izvađenih zuba, a manje plombiranih zuba kod ove grupe psihijatrijskih bolesnika. Cilj studije bio je da se istraži stanje prisutnih zuba, odredi prevalencija karijesa i ispitaju mogući faktori rizika koji doprinose postojećem stanju oralnog zdravlja kod bolesnika hospitalizovanih zbog shizofrenije. Metode. U istraživanju je učestvovalo 190 bolesnika sa shizofrenijom, hospitalizovanih na Klinici za psihijatrijske bolesti 'Dr Laza Lazarević' u Beogradu i 190 mentalno zdravih ispitanika, pacijenata Klinike za parodontologiju i oralnu medicinu Stomatološkog fakulteta u Beogradu. Ispitanicima obe grupe registrovane su vrednosti KEP indeksa, sociodemografske i ekonomske karakteristike, a bolesnicima hospitalizovanim zbog shizofrenije i karakteristike primarne bolesti. Rezultati. Vrednost KEP indeksa kod bolesnika hospitalizovanih zbog shizofrenije iznosila je 18,57 ± 7,07, a kod zdravih osoba 12,47 ± 5,64 (p = 0,000). U strukturi indeksa koji pokazuje zbir brojeva karioznih, ekstrahovanih i plombiranih zuba (KEP) kod bolesnika sa shizofrenijom, dominirali su karijesni i ekstrahovani zubi - 88,1%, a u kontrolnoj grupi plombirani zubi - 55,6%, što je bila statistički značajna razlika za sve tri posmatrane varijable. Zaključak. Bolesnici hospitalizovani zbog shizofrenije imali su dvostruko više karijesnih i izvađenih zuba, a pet puta manje plombiranih zuba od zdravih osoba. Kao prediktori povećanog KEP indeksa kod bolesnika hospitalizovanih zbog shizofrenije ustanovljeni su starost ispitanika i korišćenje antiparkinsonika.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Prevalence of dental caries in hospitalized patients with schizophrenia, Prevalencija karijesa kod bolesnika hospitalizovanih zbog shizofrenije",
volume = "73",
number = "12",
pages = "1102-1108",
doi = "10.2298/VSP150917111D"
}

Đorđević, V., Vučković, M., Miličić, B., Stefanović, V.,& Đukić-Dejanović, S.. (2016). Prevalence of dental caries in hospitalized patients with schizophrenia. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 73(12), 1102-1108.
https://doi.org/10.2298/VSP150917111D

Đorđević V, Vučković M, Miličić B, Stefanović V, Đukić-Dejanović S. Prevalence of dental caries in hospitalized patients with schizophrenia. in Vojnosanitetski pregled. 2016;73(12):1102-1108.
doi:10.2298/VSP150917111D .

Đorđević, Vladan, Vučković, Mila, Miličić, Biljana, Stefanović, Vesna, Đukić-Dejanović, Slavica, "Prevalence of dental caries in hospitalized patients with schizophrenia" in Vojnosanitetski pregled, 73, no. 12 (2016):1102-1108,
https://doi.org/10.2298/VSP150917111D . .

TY  - JOUR
AU  - Basta-Jovanović, Gordana
AU  - Suzić, S.
AU  - Savin, M.
AU  - Petronijević, Nataša
AU  - Radonjić, N.
AU  - Signuričić, S.
AU  - Vučković, Mila
AU  - Radojević-Škodrić, Sanja
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1408
AB  - Proliferative disorders including tumors are recognized as diseases of the cell cycle in which the crucial role belongs to the cyclin-dependent kinase family. The aim of this study was to investigate the expression of protein p16 in the normal kidney, and in Wilms tumor by immunohistochemistry to correlate the obtained results with tumor stage, histological type and prognostic group. We have investigated 28 cases of Wilms tumor, two Wilms tumor metastases in the lungs and one case of normal renal tissue. Protein p16 was over expressed in 20 cases of Wilms tumor. Expression of p16 was less frequent in stages III/IV/V than in stages I/III, showing no statistically significant correlation (p > 0.05). Intermediate risk groups of Wilms tumor showed more frequent p16 expression in comparison with high risk cases, showing no statistical significance (p > 0.05). Protein p16 expression was detected in all histologic types of Wilms tumor with the highest expression in the predominantly blastemal type (50%). There was a statistically significant difference between p16 expression in this and its expression in other histological types (p  lt  0.05). The correlation between p16 expression and the predominantly blastemal histological type was statistically significant and showed that in such cases tumor cells can proliferate even in the presence of p16.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria
T1  - Immunohistochemical expression of protein p16 in Wilms' tumor
VL  - 58
IS  - 4
SP  - 297
EP  - 306
DO  - 10.2298/AVB0804297B
ER  - 

@article{
author = "Basta-Jovanović, Gordana and Suzić, S. and Savin, M. and Petronijević, Nataša and Radonjić, N. and Signuričić, S. and Vučković, Mila and Radojević-Škodrić, Sanja",
year = "2008",
abstract = "Proliferative disorders including tumors are recognized as diseases of the cell cycle in which the crucial role belongs to the cyclin-dependent kinase family. The aim of this study was to investigate the expression of protein p16 in the normal kidney, and in Wilms tumor by immunohistochemistry to correlate the obtained results with tumor stage, histological type and prognostic group. We have investigated 28 cases of Wilms tumor, two Wilms tumor metastases in the lungs and one case of normal renal tissue. Protein p16 was over expressed in 20 cases of Wilms tumor. Expression of p16 was less frequent in stages III/IV/V than in stages I/III, showing no statistically significant correlation (p > 0.05). Intermediate risk groups of Wilms tumor showed more frequent p16 expression in comparison with high risk cases, showing no statistical significance (p > 0.05). Protein p16 expression was detected in all histologic types of Wilms tumor with the highest expression in the predominantly blastemal type (50%). There was a statistically significant difference between p16 expression in this and its expression in other histological types (p  lt  0.05). The correlation between p16 expression and the predominantly blastemal histological type was statistically significant and showed that in such cases tumor cells can proliferate even in the presence of p16.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria",
title = "Immunohistochemical expression of protein p16 in Wilms' tumor",
volume = "58",
number = "4",
pages = "297-306",
doi = "10.2298/AVB0804297B"
}

Basta-Jovanović, G., Suzić, S., Savin, M., Petronijević, N., Radonjić, N., Signuričić, S., Vučković, M.,& Radojević-Škodrić, S.. (2008). Immunohistochemical expression of protein p16 in Wilms' tumor. in Acta Veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 58(4), 297-306.
https://doi.org/10.2298/AVB0804297B

Basta-Jovanović G, Suzić S, Savin M, Petronijević N, Radonjić N, Signuričić S, Vučković M, Radojević-Škodrić S. Immunohistochemical expression of protein p16 in Wilms' tumor. in Acta Veterinaria. 2008;58(4):297-306.
doi:10.2298/AVB0804297B .

Basta-Jovanović, Gordana, Suzić, S., Savin, M., Petronijević, Nataša, Radonjić, N., Signuričić, S., Vučković, Mila, Radojević-Škodrić, Sanja, "Immunohistochemical expression of protein p16 in Wilms' tumor" in Acta Veterinaria, 58, no. 4 (2008):297-306,
https://doi.org/10.2298/AVB0804297B . .

TY  - JOUR
AU  - Basta-Jovanović, Gordana
AU  - Gvozdenović, E.
AU  - Dimitrijević, I.
AU  - Brašanac, Dimitrije
AU  - Vučković, Mila
AU  - Kalezić, Nevena
AU  - Baralić, I.
AU  - Radojević-Škodrić, Sanja
AU  - Arsić, D.
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1395
AB  - The aim of our study was to investigate the expression of γ-catenin in normal kidney and in Wilms' tumor by immunohistochemistry and to correlate the results with tumor stage, histological type, and prognostic group. We investigated 28 cases of Wilms' tumor, 2 Wilms' tumor metastases in lungs, and 1 specimen of normal renal tissue. Expression of γ-catenin was detected in 14 cases. There was a weak inverse relationship between γ-catenin expression and tumor stage. Expression of γ-catenin was detected in various histologic types of Wilms' tumor, but there was no statistically significant correlation, except in cases with diffuse anaplasia that were negative. In 2 metastatic cases and in the case of bilateral Wilms' tumor γ-catenin immunostaining was not observed Our findings suggest an absence of strong correlation between the loss of γ-catenin and unfavorable outcome.
T2  - Fetal & Pediatric Pathology
T1  - Immunohistochemical analysis of gamma catenin in Wilms' tumors
VL  - 27
IS  - 2
SP  - 63
EP  - 70
DO  - 10.1080/15513810802028704
ER  - 

@article{
author = "Basta-Jovanović, Gordana and Gvozdenović, E. and Dimitrijević, I. and Brašanac, Dimitrije and Vučković, Mila and Kalezić, Nevena and Baralić, I. and Radojević-Škodrić, Sanja and Arsić, D.",
year = "2008",
abstract = "The aim of our study was to investigate the expression of γ-catenin in normal kidney and in Wilms' tumor by immunohistochemistry and to correlate the results with tumor stage, histological type, and prognostic group. We investigated 28 cases of Wilms' tumor, 2 Wilms' tumor metastases in lungs, and 1 specimen of normal renal tissue. Expression of γ-catenin was detected in 14 cases. There was a weak inverse relationship between γ-catenin expression and tumor stage. Expression of γ-catenin was detected in various histologic types of Wilms' tumor, but there was no statistically significant correlation, except in cases with diffuse anaplasia that were negative. In 2 metastatic cases and in the case of bilateral Wilms' tumor γ-catenin immunostaining was not observed Our findings suggest an absence of strong correlation between the loss of γ-catenin and unfavorable outcome.",
journal = "Fetal & Pediatric Pathology",
title = "Immunohistochemical analysis of gamma catenin in Wilms' tumors",
volume = "27",
number = "2",
pages = "63-70",
doi = "10.1080/15513810802028704"
}

Basta-Jovanović, G., Gvozdenović, E., Dimitrijević, I., Brašanac, D., Vučković, M., Kalezić, N., Baralić, I., Radojević-Škodrić, S.,& Arsić, D.. (2008). Immunohistochemical analysis of gamma catenin in Wilms' tumors. in Fetal & Pediatric Pathology, 27(2), 63-70.
https://doi.org/10.1080/15513810802028704

Basta-Jovanović G, Gvozdenović E, Dimitrijević I, Brašanac D, Vučković M, Kalezić N, Baralić I, Radojević-Škodrić S, Arsić D. Immunohistochemical analysis of gamma catenin in Wilms' tumors. in Fetal & Pediatric Pathology. 2008;27(2):63-70.
doi:10.1080/15513810802028704 .

Basta-Jovanović, Gordana, Gvozdenović, E., Dimitrijević, I., Brašanac, Dimitrije, Vučković, Mila, Kalezić, Nevena, Baralić, I., Radojević-Škodrić, Sanja, Arsić, D., "Immunohistochemical analysis of gamma catenin in Wilms' tumors" in Fetal & Pediatric Pathology, 27, no. 2 (2008):63-70,
https://doi.org/10.1080/15513810802028704 . .

TY  - JOUR
AU  - Radojević-Škodrić, Sanja
AU  - Đuricić, S.
AU  - Vučković, Mila
AU  - Dimitrijević, I.
AU  - Lazić, Miodrag
AU  - Stojšić, Z.
AU  - Brašanac, Dimitrije
AU  - Basta-Jovanović, Gordana
PY  - 2007
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1375
AB  - Abnormalities in cell cycle regulators and subsequent deregulation of G1-S transition may be one of the most important biological events in the malignant transformation of cells. The aim of this study was to investigate the expression of Cyclin E in the normal kidney, and in Wilms tumor, and to correlate the results with tumor stage, histological type and prognostic group. We have investigated 28 cases of Wilms tumor, two Wilms tumor metastases in lungs and one case of normal renal tissue. Correlation of semiquantitatively scored cyclin E levels with histopathological parameters was performed for all cases. Diffuse expression of cyclin E was more frequent in the blastemal (without epithelial component) then in the epithelial (without blastemal) component. This correlation showed high significance (p=0.001). Diffuse expression of cyclin E was more frequent in stage III/IV/V (71.4%) than in stage I/II (42.9%), showing no significant correlation (p>0.05). The intermediate risk group of Wilms tumor showed more frequent cyclin E diffuse expression (66.7%) in comparison with high risk cases (20%), showing statistical significance (p lt 0.05). Our findings suggest that diffuse expression of cyclin E is associated with the prognostic group and tumor stage. Also, cyclin E expression is more pronounced in the blastemal component than in the epithelial component.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria
T1  - Immunohistochemical analysis of cyclin E in Wilms tumors
VL  - 57
IS  - 5-6
SP  - 453
EP  - 464
DO  - 10.2298/AVB0706453R
ER  - 

@article{
author = "Radojević-Škodrić, Sanja and Đuricić, S. and Vučković, Mila and Dimitrijević, I. and Lazić, Miodrag and Stojšić, Z. and Brašanac, Dimitrije and Basta-Jovanović, Gordana",
year = "2007",
abstract = "Abnormalities in cell cycle regulators and subsequent deregulation of G1-S transition may be one of the most important biological events in the malignant transformation of cells. The aim of this study was to investigate the expression of Cyclin E in the normal kidney, and in Wilms tumor, and to correlate the results with tumor stage, histological type and prognostic group. We have investigated 28 cases of Wilms tumor, two Wilms tumor metastases in lungs and one case of normal renal tissue. Correlation of semiquantitatively scored cyclin E levels with histopathological parameters was performed for all cases. Diffuse expression of cyclin E was more frequent in the blastemal (without epithelial component) then in the epithelial (without blastemal) component. This correlation showed high significance (p=0.001). Diffuse expression of cyclin E was more frequent in stage III/IV/V (71.4%) than in stage I/II (42.9%), showing no significant correlation (p>0.05). The intermediate risk group of Wilms tumor showed more frequent cyclin E diffuse expression (66.7%) in comparison with high risk cases (20%), showing statistical significance (p lt 0.05). Our findings suggest that diffuse expression of cyclin E is associated with the prognostic group and tumor stage. Also, cyclin E expression is more pronounced in the blastemal component than in the epithelial component.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria",
title = "Immunohistochemical analysis of cyclin E in Wilms tumors",
volume = "57",
number = "5-6",
pages = "453-464",
doi = "10.2298/AVB0706453R"
}

Radojević-Škodrić, S., Đuricić, S., Vučković, M., Dimitrijević, I., Lazić, M., Stojšić, Z., Brašanac, D.,& Basta-Jovanović, G.. (2007). Immunohistochemical analysis of cyclin E in Wilms tumors. in Acta Veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 57(5-6), 453-464.
https://doi.org/10.2298/AVB0706453R

Radojević-Škodrić S, Đuricić S, Vučković M, Dimitrijević I, Lazić M, Stojšić Z, Brašanac D, Basta-Jovanović G. Immunohistochemical analysis of cyclin E in Wilms tumors. in Acta Veterinaria. 2007;57(5-6):453-464.
doi:10.2298/AVB0706453R .

Radojević-Škodrić, Sanja, Đuricić, S., Vučković, Mila, Dimitrijević, I., Lazić, Miodrag, Stojšić, Z., Brašanac, Dimitrije, Basta-Jovanović, Gordana, "Immunohistochemical analysis of cyclin E in Wilms tumors" in Acta Veterinaria, 57, no. 5-6 (2007):453-464,
https://doi.org/10.2298/AVB0706453R . .