TY  - JOUR
AU  - Sabljak, Vera
AU  - Živaljević, Vladan
AU  - Miličić, Biljana
AU  - Paunović, Ivan
AU  - Tosković, Anka R.
AU  - Stevanović, Ksenija
AU  - Taušanović, Katarina
AU  - Marković, Dejan Z.
AU  - Stojanović, Marina
AU  - Lakićević, Mirko
AU  - Jovanović, Milan D.
AU  - Diklić, Aleksandar
AU  - Kalezić, Nevena
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2220
AB  - Objective: To investigate the incidence and identify risk factors for the occurrence of intraoperative hypertension (IOH) during surgery for primary hyperparathyroidism (pHPT). Subjects and Methods: The study included 269 patients surgically treated between January 2008 and January 2012 for pHPT. IOH was defined as an increase in systolic blood pressure >= 20% compared to baseline values which lasted for 15min. The investigated influence were demographic characteristics, surgical risk score related to physical status (based on the American Society of Anesthesiologists [ASA] classification), comorbidities, type and duration of surgery, and duration of anesthesia on IOH occurrence. The investigated factors were obtained from the patients' medical history, anesthesia charts, and the daily practice database. Logistic regression analysis was done to determine the predictors of IOH. Results: Of the 269 patients, 153 (56.9%) had IOH. Based on the univariate analysis, age, body mass index, ASA status, duration of anesthesia, and preoperative hypertension were risk factors for the occurrence of IOH. Multivariate analysis showed that independent predictors of IOH were a history of hypertension (OR = 2.080, 95% CI: 1.102-3.925, p = 0.024) and age (OR = 0.569, 95% CI: 0.360-0.901, p = 0.016). Conclusion: In this study, a high percentage (56%) of the patients developed IOH during surgery for pHPT, which indicates that special attention should be paid to these patients, especially to the high-risk groups: older patients and those with a history of hypertension. Further, this study showed that advanced age and hypertension as a coexisting disease prior to parathyroid surgery were independent risk factors for the occurrence of IOH.
PB  - Karger, Basel
T2  - Medical Principles & Practice
T1  - Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism
VL  - 26
IS  - 4
SP  - 381
EP  - 386
DO  - 10.1159/000475597
ER  - 

@article{
author = "Sabljak, Vera and Živaljević, Vladan and Miličić, Biljana and Paunović, Ivan and Tosković, Anka R. and Stevanović, Ksenija and Taušanović, Katarina and Marković, Dejan Z. and Stojanović, Marina and Lakićević, Mirko and Jovanović, Milan D. and Diklić, Aleksandar and Kalezić, Nevena",
year = "2017",
abstract = "Objective: To investigate the incidence and identify risk factors for the occurrence of intraoperative hypertension (IOH) during surgery for primary hyperparathyroidism (pHPT). Subjects and Methods: The study included 269 patients surgically treated between January 2008 and January 2012 for pHPT. IOH was defined as an increase in systolic blood pressure >= 20% compared to baseline values which lasted for 15min. The investigated influence were demographic characteristics, surgical risk score related to physical status (based on the American Society of Anesthesiologists [ASA] classification), comorbidities, type and duration of surgery, and duration of anesthesia on IOH occurrence. The investigated factors were obtained from the patients' medical history, anesthesia charts, and the daily practice database. Logistic regression analysis was done to determine the predictors of IOH. Results: Of the 269 patients, 153 (56.9%) had IOH. Based on the univariate analysis, age, body mass index, ASA status, duration of anesthesia, and preoperative hypertension were risk factors for the occurrence of IOH. Multivariate analysis showed that independent predictors of IOH were a history of hypertension (OR = 2.080, 95% CI: 1.102-3.925, p = 0.024) and age (OR = 0.569, 95% CI: 0.360-0.901, p = 0.016). Conclusion: In this study, a high percentage (56%) of the patients developed IOH during surgery for pHPT, which indicates that special attention should be paid to these patients, especially to the high-risk groups: older patients and those with a history of hypertension. Further, this study showed that advanced age and hypertension as a coexisting disease prior to parathyroid surgery were independent risk factors for the occurrence of IOH.",
publisher = "Karger, Basel",
journal = "Medical Principles & Practice",
title = "Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism",
volume = "26",
number = "4",
pages = "381-386",
doi = "10.1159/000475597"
}

Sabljak, V., Živaljević, V., Miličić, B., Paunović, I., Tosković, A. R., Stevanović, K., Taušanović, K., Marković, D. Z., Stojanović, M., Lakićević, M., Jovanović, M. D., Diklić, A.,& Kalezić, N.. (2017). Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism. in Medical Principles & Practice
Karger, Basel., 26(4), 381-386.
https://doi.org/10.1159/000475597

Sabljak V, Živaljević V, Miličić B, Paunović I, Tosković AR, Stevanović K, Taušanović K, Marković DZ, Stojanović M, Lakićević M, Jovanović MD, Diklić A, Kalezić N. Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism. in Medical Principles & Practice. 2017;26(4):381-386.
doi:10.1159/000475597 .

Sabljak, Vera, Živaljević, Vladan, Miličić, Biljana, Paunović, Ivan, Tosković, Anka R., Stevanović, Ksenija, Taušanović, Katarina, Marković, Dejan Z., Stojanović, Marina, Lakićević, Mirko, Jovanović, Milan D., Diklić, Aleksandar, Kalezić, Nevena, "Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism" in Medical Principles & Practice, 26, no. 4 (2017):381-386,
https://doi.org/10.1159/000475597 . .