TY  - JOUR
AU  - Milovanović, Tamara
AU  - Dragašević, Sanja
AU  - Stojković-Lalošević, Milica
AU  - Zgradić, Sanja
AU  - Miličić, Biljana
AU  - Dumić, Igor
AU  - Kmezić, Stefan
AU  - Saponjski, Dušan
AU  - Antić, Andrija
AU  - Marković, Velimir
AU  - Popović, Dragan
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2416
AB  - Background and Objectives: The aim of the study was to determine the association between presences of fatty pancreas (FP) with the features of metabolic syndrome (MeS) in patients with non-alcoholic fatty liver disease (NAFLD) and to establish a new noninvasive scoring system for the prediction of FP in patients with NAFLD. Material and Methods: 143 patients with NAFLD were classified according to FP severity grade into the two groups and evaluated for diagnostic criteria of MeS. All patients underwent sonographic examination with adiposity measurements and the liver biopsy. Liver fibrosis was evaluated semi-quantitatively according to the METAVIR scoring system and using non-invasive markers of hepatic fibrosis. Results: Waist circumference (WC) was predictive for increased risk of FP in NAFLD patients. Elevated fasting plasma glucose, total cholesterol, serum amylase and lipase levels were associated with presence of severe FP (p value = 0.052, p value = 0.007, p value = 0.014; p value = 0.024, respectively). Presence of increased amounts of mesenteric fat was associated with severe FP (p value = 0.013). The results of this study demonstrated highly significant association between NAFLD and presence of FP. The model for predicting the presence of FP was designed with probability value above 6.5. Conclusion: Pancreatic fat accumulation leads to worsening of pancreatic function which in turns exacerbates severity of metabolic syndrome associated with both, NAFLD and NAFPD.
PB  - Mdpi, Basel
T2  - Medicina-Lithuania
T1  - Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease-A Cross Sectional Study
VL  - 55
IS  - 10
DO  - 10.3390/medicina55100697
ER  - 

@article{
author = "Milovanović, Tamara and Dragašević, Sanja and Stojković-Lalošević, Milica and Zgradić, Sanja and Miličić, Biljana and Dumić, Igor and Kmezić, Stefan and Saponjski, Dušan and Antić, Andrija and Marković, Velimir and Popović, Dragan",
year = "2019",
abstract = "Background and Objectives: The aim of the study was to determine the association between presences of fatty pancreas (FP) with the features of metabolic syndrome (MeS) in patients with non-alcoholic fatty liver disease (NAFLD) and to establish a new noninvasive scoring system for the prediction of FP in patients with NAFLD. Material and Methods: 143 patients with NAFLD were classified according to FP severity grade into the two groups and evaluated for diagnostic criteria of MeS. All patients underwent sonographic examination with adiposity measurements and the liver biopsy. Liver fibrosis was evaluated semi-quantitatively according to the METAVIR scoring system and using non-invasive markers of hepatic fibrosis. Results: Waist circumference (WC) was predictive for increased risk of FP in NAFLD patients. Elevated fasting plasma glucose, total cholesterol, serum amylase and lipase levels were associated with presence of severe FP (p value = 0.052, p value = 0.007, p value = 0.014; p value = 0.024, respectively). Presence of increased amounts of mesenteric fat was associated with severe FP (p value = 0.013). The results of this study demonstrated highly significant association between NAFLD and presence of FP. The model for predicting the presence of FP was designed with probability value above 6.5. Conclusion: Pancreatic fat accumulation leads to worsening of pancreatic function which in turns exacerbates severity of metabolic syndrome associated with both, NAFLD and NAFPD.",
publisher = "Mdpi, Basel",
journal = "Medicina-Lithuania",
title = "Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease-A Cross Sectional Study",
volume = "55",
number = "10",
doi = "10.3390/medicina55100697"
}

Milovanović, T., Dragašević, S., Stojković-Lalošević, M., Zgradić, S., Miličić, B., Dumić, I., Kmezić, S., Saponjski, D., Antić, A., Marković, V.,& Popović, D.. (2019). Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease-A Cross Sectional Study. in Medicina-Lithuania
Mdpi, Basel., 55(10).
https://doi.org/10.3390/medicina55100697

Milovanović T, Dragašević S, Stojković-Lalošević M, Zgradić S, Miličić B, Dumić I, Kmezić S, Saponjski D, Antić A, Marković V, Popović D. Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease-A Cross Sectional Study. in Medicina-Lithuania. 2019;55(10).
doi:10.3390/medicina55100697 .

Milovanović, Tamara, Dragašević, Sanja, Stojković-Lalošević, Milica, Zgradić, Sanja, Miličić, Biljana, Dumić, Igor, Kmezić, Stefan, Saponjski, Dušan, Antić, Andrija, Marković, Velimir, Popović, Dragan, "Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease-A Cross Sectional Study" in Medicina-Lithuania, 55, no. 10 (2019),
https://doi.org/10.3390/medicina55100697 . .