TY  - JOUR
AU  - Stojanović, Marina
AU  - Kalezić, Nevena
AU  - Miličić, Biljana
AU  - Tosković, Anka R.
AU  - Stevanović, Ksenija
AU  - Antonijević, Vesna
AU  - Lakićević, Mirko
AU  - Bagi, Bojan
AU  - Živaljević, Vladan
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2328
AB  - Introduction/Objective Intraoperative variations in blood pressure and/or cardiac dysrhythmias (IOVBP/CD) represent one of the most common causes of morbidity and mortality in surgical patients. The aim of the study was to determine the incidence and risk factors for IOVBP/CD in thyroid surgery patients with comorbidities. Methods The study included 1,252 euthyroid patients with ASA 2 and ASA 3 status (American Society of Anesthesiologists - physical status classification) who underwent thyroid surgery. The following risk factors were examined: sex, age, body mass index (BMI), ASA status, admission diagnoses, type of operation, duration of surgery, time under general anesthesia, difficult intubation of trachea, and coexisting diseases - hypertension, cardiomyopathy, cardiac arrhythmias, angina pectoris, diabetes mellitus, kidney disease. The following intraoperative events were recorded: hypertension, severe hypertension, hypotension, and cardiac arrhythmias. We used Pearson χ2 square test, univariate, and multivariate logistic regression for statistical analysis. Results The majority of patients were female (86.3%). In 903 (72.1%) patients IOVBP/CD were detected. The most common problem was intraoperative hypertension (61.4%). Eight risk factors for IOVBP/CD were registered by univariate analysis: advanced age, ASA 3 status, BMI > 25 kg/m2, duration of surgery, time under general anesthesia, hypertension, and cardiomyopathy as a coexisting disease. The multivariate regression model identified three independent predictors for IOVBP/CD: age, hypertension, and cardiomyopathy. Conclusion IOVBP/CD are common in thyroid surgery. The most common is intraoperative hypertension. Older age, hypertension, and cardiomyopathy as a coexisting disease are independent risk factors for IOVBP/CD.
AB  - Uvod/Cilj Intraoperativne varijacije krvnog pritiska i/ ili srčane disritmije (IVKP/SD) jedan su od najčešćih uzročnika morbiditeta i mortaliteta hirurških bolesnika. Cilj studije je bio da ispita učestalost i faktore rizika za pojavu IVKP/SD u tireoidnoj hirurgiji kod bolesnika sa komorbiditetima. Metode Ispitivanje je obuhvatilo 1252 eutireoidna bolesnika ASA 2 i ASA 3 statusa podvrgnutih tireoidnoj hirurgiji. Ispitivan je uticaj sledećih faktora rizika: pol, starost, indeks telesne mase (ITM), ASA status, prijemna dijagnoza, tip operacije, trajanje operacije, trajanje anestezije, otežana intubacija traheje, kao i komorbiditeti: hipertenzija, kardiomiopatija, srčane aritmije, angina pektoris, dijabetes melitus, bolesti bubrega. Registrovani su intraoperativno: hipertenzija, hipertenzivna kriza, hipotenzija i srčane aritmije. Korišćen je Pirsonov χ2-test, univarijantna i multivarijantna regresiona analiza za statističku obradu podataka. Rezultati Većinu bolesnika su činile žene (86,3%). IVKP/ SD su registrovani kod 903 (72,1%) bolesnika. Najčešći poremećaj je bila intraoperativna hipertenzija - 61,4%. Univarijantnom analizom je registrovano sedam faktora rizika za pojavu IVKP/SD: godine života, ASA 3 status, ITM > 25 kg/m2, trajanje hirurgije, trajanje anestezije, hipertenzija i kardiomiopatija kao komorbiditet. Multivarijantnom regresionom analizom izdvojila su se tri nezavisna prediktora pojave IVKP/SD: godine starosti, hipertenzija i kardiomiopatija. Zaključak IVKP/SD su česte u tireoidnoj hirurgiji. Najčešća je intraoperativna hipertenzija. Starije životno doba, hipertenzija i kardiomiopatija kao koegzistirajuće bolesti su nezavisni faktori rizika za pojavu IVKP/SD.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery
T1  - Faktori rizika za pojavu intraoperativnih varijacija vrednosti krvnog pritiska i srčanih disritmija tokom tireoidne hirurgije
VL  - 146
IS  - 3-4
SP  - 163
EP  - 168
DO  - 10.2298/SARH170522156S
ER  - 

@article{
author = "Stojanović, Marina and Kalezić, Nevena and Miličić, Biljana and Tosković, Anka R. and Stevanović, Ksenija and Antonijević, Vesna and Lakićević, Mirko and Bagi, Bojan and Živaljević, Vladan",
year = "2018",
abstract = "Introduction/Objective Intraoperative variations in blood pressure and/or cardiac dysrhythmias (IOVBP/CD) represent one of the most common causes of morbidity and mortality in surgical patients. The aim of the study was to determine the incidence and risk factors for IOVBP/CD in thyroid surgery patients with comorbidities. Methods The study included 1,252 euthyroid patients with ASA 2 and ASA 3 status (American Society of Anesthesiologists - physical status classification) who underwent thyroid surgery. The following risk factors were examined: sex, age, body mass index (BMI), ASA status, admission diagnoses, type of operation, duration of surgery, time under general anesthesia, difficult intubation of trachea, and coexisting diseases - hypertension, cardiomyopathy, cardiac arrhythmias, angina pectoris, diabetes mellitus, kidney disease. The following intraoperative events were recorded: hypertension, severe hypertension, hypotension, and cardiac arrhythmias. We used Pearson χ2 square test, univariate, and multivariate logistic regression for statistical analysis. Results The majority of patients were female (86.3%). In 903 (72.1%) patients IOVBP/CD were detected. The most common problem was intraoperative hypertension (61.4%). Eight risk factors for IOVBP/CD were registered by univariate analysis: advanced age, ASA 3 status, BMI > 25 kg/m2, duration of surgery, time under general anesthesia, hypertension, and cardiomyopathy as a coexisting disease. The multivariate regression model identified three independent predictors for IOVBP/CD: age, hypertension, and cardiomyopathy. Conclusion IOVBP/CD are common in thyroid surgery. The most common is intraoperative hypertension. Older age, hypertension, and cardiomyopathy as a coexisting disease are independent risk factors for IOVBP/CD., Uvod/Cilj Intraoperativne varijacije krvnog pritiska i/ ili srčane disritmije (IVKP/SD) jedan su od najčešćih uzročnika morbiditeta i mortaliteta hirurških bolesnika. Cilj studije je bio da ispita učestalost i faktore rizika za pojavu IVKP/SD u tireoidnoj hirurgiji kod bolesnika sa komorbiditetima. Metode Ispitivanje je obuhvatilo 1252 eutireoidna bolesnika ASA 2 i ASA 3 statusa podvrgnutih tireoidnoj hirurgiji. Ispitivan je uticaj sledećih faktora rizika: pol, starost, indeks telesne mase (ITM), ASA status, prijemna dijagnoza, tip operacije, trajanje operacije, trajanje anestezije, otežana intubacija traheje, kao i komorbiditeti: hipertenzija, kardiomiopatija, srčane aritmije, angina pektoris, dijabetes melitus, bolesti bubrega. Registrovani su intraoperativno: hipertenzija, hipertenzivna kriza, hipotenzija i srčane aritmije. Korišćen je Pirsonov χ2-test, univarijantna i multivarijantna regresiona analiza za statističku obradu podataka. Rezultati Većinu bolesnika su činile žene (86,3%). IVKP/ SD su registrovani kod 903 (72,1%) bolesnika. Najčešći poremećaj je bila intraoperativna hipertenzija - 61,4%. Univarijantnom analizom je registrovano sedam faktora rizika za pojavu IVKP/SD: godine života, ASA 3 status, ITM > 25 kg/m2, trajanje hirurgije, trajanje anestezije, hipertenzija i kardiomiopatija kao komorbiditet. Multivarijantnom regresionom analizom izdvojila su se tri nezavisna prediktora pojave IVKP/SD: godine starosti, hipertenzija i kardiomiopatija. Zaključak IVKP/SD su česte u tireoidnoj hirurgiji. Najčešća je intraoperativna hipertenzija. Starije životno doba, hipertenzija i kardiomiopatija kao koegzistirajuće bolesti su nezavisni faktori rizika za pojavu IVKP/SD.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery, Faktori rizika za pojavu intraoperativnih varijacija vrednosti krvnog pritiska i srčanih disritmija tokom tireoidne hirurgije",
volume = "146",
number = "3-4",
pages = "163-168",
doi = "10.2298/SARH170522156S"
}

Stojanović, M., Kalezić, N., Miličić, B., Tosković, A. R., Stevanović, K., Antonijević, V., Lakićević, M., Bagi, B.,& Živaljević, V.. (2018). Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 146(3-4), 163-168.
https://doi.org/10.2298/SARH170522156S

Stojanović M, Kalezić N, Miličić B, Tosković AR, Stevanović K, Antonijević V, Lakićević M, Bagi B, Živaljević V. Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery. in Srpski arhiv za celokupno lekarstvo. 2018;146(3-4):163-168.
doi:10.2298/SARH170522156S .

Stojanović, Marina, Kalezić, Nevena, Miličić, Biljana, Tosković, Anka R., Stevanović, Ksenija, Antonijević, Vesna, Lakićević, Mirko, Bagi, Bojan, Živaljević, Vladan, "Risk factors for intraoperative variations in blood pressure and cardiac dysrhythmia during thyroid surgery" in Srpski arhiv za celokupno lekarstvo, 146, no. 3-4 (2018):163-168,
https://doi.org/10.2298/SARH170522156S . .

TY  - JOUR
AU  - Sabljak, Vera
AU  - Živaljević, Vladan
AU  - Miličić, Biljana
AU  - Paunović, Ivan
AU  - Tosković, Anka R.
AU  - Stevanović, Ksenija
AU  - Taušanović, Katarina
AU  - Marković, Dejan Z.
AU  - Stojanović, Marina
AU  - Lakićević, Mirko
AU  - Jovanović, Milan D.
AU  - Diklić, Aleksandar
AU  - Kalezić, Nevena
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2220
AB  - Objective: To investigate the incidence and identify risk factors for the occurrence of intraoperative hypertension (IOH) during surgery for primary hyperparathyroidism (pHPT). Subjects and Methods: The study included 269 patients surgically treated between January 2008 and January 2012 for pHPT. IOH was defined as an increase in systolic blood pressure >= 20% compared to baseline values which lasted for 15min. The investigated influence were demographic characteristics, surgical risk score related to physical status (based on the American Society of Anesthesiologists [ASA] classification), comorbidities, type and duration of surgery, and duration of anesthesia on IOH occurrence. The investigated factors were obtained from the patients' medical history, anesthesia charts, and the daily practice database. Logistic regression analysis was done to determine the predictors of IOH. Results: Of the 269 patients, 153 (56.9%) had IOH. Based on the univariate analysis, age, body mass index, ASA status, duration of anesthesia, and preoperative hypertension were risk factors for the occurrence of IOH. Multivariate analysis showed that independent predictors of IOH were a history of hypertension (OR = 2.080, 95% CI: 1.102-3.925, p = 0.024) and age (OR = 0.569, 95% CI: 0.360-0.901, p = 0.016). Conclusion: In this study, a high percentage (56%) of the patients developed IOH during surgery for pHPT, which indicates that special attention should be paid to these patients, especially to the high-risk groups: older patients and those with a history of hypertension. Further, this study showed that advanced age and hypertension as a coexisting disease prior to parathyroid surgery were independent risk factors for the occurrence of IOH.
PB  - Karger, Basel
T2  - Medical Principles & Practice
T1  - Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism
VL  - 26
IS  - 4
SP  - 381
EP  - 386
DO  - 10.1159/000475597
ER  - 

@article{
author = "Sabljak, Vera and Živaljević, Vladan and Miličić, Biljana and Paunović, Ivan and Tosković, Anka R. and Stevanović, Ksenija and Taušanović, Katarina and Marković, Dejan Z. and Stojanović, Marina and Lakićević, Mirko and Jovanović, Milan D. and Diklić, Aleksandar and Kalezić, Nevena",
year = "2017",
abstract = "Objective: To investigate the incidence and identify risk factors for the occurrence of intraoperative hypertension (IOH) during surgery for primary hyperparathyroidism (pHPT). Subjects and Methods: The study included 269 patients surgically treated between January 2008 and January 2012 for pHPT. IOH was defined as an increase in systolic blood pressure >= 20% compared to baseline values which lasted for 15min. The investigated influence were demographic characteristics, surgical risk score related to physical status (based on the American Society of Anesthesiologists [ASA] classification), comorbidities, type and duration of surgery, and duration of anesthesia on IOH occurrence. The investigated factors were obtained from the patients' medical history, anesthesia charts, and the daily practice database. Logistic regression analysis was done to determine the predictors of IOH. Results: Of the 269 patients, 153 (56.9%) had IOH. Based on the univariate analysis, age, body mass index, ASA status, duration of anesthesia, and preoperative hypertension were risk factors for the occurrence of IOH. Multivariate analysis showed that independent predictors of IOH were a history of hypertension (OR = 2.080, 95% CI: 1.102-3.925, p = 0.024) and age (OR = 0.569, 95% CI: 0.360-0.901, p = 0.016). Conclusion: In this study, a high percentage (56%) of the patients developed IOH during surgery for pHPT, which indicates that special attention should be paid to these patients, especially to the high-risk groups: older patients and those with a history of hypertension. Further, this study showed that advanced age and hypertension as a coexisting disease prior to parathyroid surgery were independent risk factors for the occurrence of IOH.",
publisher = "Karger, Basel",
journal = "Medical Principles & Practice",
title = "Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism",
volume = "26",
number = "4",
pages = "381-386",
doi = "10.1159/000475597"
}

Sabljak, V., Živaljević, V., Miličić, B., Paunović, I., Tosković, A. R., Stevanović, K., Taušanović, K., Marković, D. Z., Stojanović, M., Lakićević, M., Jovanović, M. D., Diklić, A.,& Kalezić, N.. (2017). Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism. in Medical Principles & Practice
Karger, Basel., 26(4), 381-386.
https://doi.org/10.1159/000475597

Sabljak V, Živaljević V, Miličić B, Paunović I, Tosković AR, Stevanović K, Taušanović K, Marković DZ, Stojanović M, Lakićević M, Jovanović MD, Diklić A, Kalezić N. Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism. in Medical Principles & Practice. 2017;26(4):381-386.
doi:10.1159/000475597 .

Sabljak, Vera, Živaljević, Vladan, Miličić, Biljana, Paunović, Ivan, Tosković, Anka R., Stevanović, Ksenija, Taušanović, Katarina, Marković, Dejan Z., Stojanović, Marina, Lakićević, Mirko, Jovanović, Milan D., Diklić, Aleksandar, Kalezić, Nevena, "Risk Factors for Intraoperative Hypertension during Surgery for Primary Hyperparathyroidism" in Medical Principles & Practice, 26, no. 4 (2017):381-386,
https://doi.org/10.1159/000475597 . .