Barac, Aleksandra

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orcid::0000-0002-0132-2277
  • Barac, Aleksandra (4)
Projects

Author's Bibliography

Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis

Barac, Aleksandra; Stevanović, Goran; Pekmezović, Marina; Rakočević, Zoran; Stošović, Rajica; Erović, Boban; Tomić-Spirić, Vesna

(Oxford Univ Press, Oxford, 2018)

TY  - JOUR
AU  - Barac, Aleksandra
AU  - Stevanović, Goran
AU  - Pekmezović, Marina
AU  - Rakočević, Zoran
AU  - Stošović, Rajica
AU  - Erović, Boban
AU  - Tomić-Spirić, Vesna
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2310
AB  - Dysbiosis of the microbiome on the airway mucosa leads to the development of chronic inflammatory and allergic disorders. The aim of this study was to consider the potential diagnostic criteria for allergic fungal rhinosinusitis (AFRS) and nonallergic fungal rhinosinusitis (FRS), and the role of fungal presence in an environment for the development of AFRS. In this study, 136 patients were divided into two groups: patients with positive specific immunoglobulin E (sIgE) and fungal finding (AFRS group), and patients with negative sIgE and positive fungal finding (FRS group). The study design included: anamnesis data, sIgE, eosinophil count and skin-prick test, rhinology and computerized tomography (CT) observation and mycological finding. Our results showed: (i) the prevalence in Serbia is: AFRS 1.3%, FRS 2.8%; (ii) 30.4% patients with sIgE+ had more often severe and recurrent chronic rhinosinusitis (CRS) (P = .005) and the presence of polyps (P = .025); (iii) 46.4% patients with sIgE+ had positive fungi on the sinonasal mucosa and were considered as AFRS; (iv) patients with AFRS had more frequent asthma (P = .024) and chronicity of CRS > 10 years (P = .000). The persistent fungal presence and prolonged duration of CRS could be a silent threat for the progression of inflammation and development of FRS. Lavage with hypertonic-NaCl should be included in the everyday hygiene routine in an effort to decrease fungal load and antigenic exposure. The presence of allergological parameters and better response to corticosteroid therapy in AFRS patients should be considered as crucial diagnostic criteria for AFRS.
PB  - Oxford Univ Press, Oxford
T2  - Medical Mycology
T1  - Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis
VL  - 56
IS  - 2
SP  - 162
EP  - 171
DO  - 10.1093/mmy/myx032
ER  - 
@article{
author = "Barac, Aleksandra and Stevanović, Goran and Pekmezović, Marina and Rakočević, Zoran and Stošović, Rajica and Erović, Boban and Tomić-Spirić, Vesna",
year = "2018",
abstract = "Dysbiosis of the microbiome on the airway mucosa leads to the development of chronic inflammatory and allergic disorders. The aim of this study was to consider the potential diagnostic criteria for allergic fungal rhinosinusitis (AFRS) and nonallergic fungal rhinosinusitis (FRS), and the role of fungal presence in an environment for the development of AFRS. In this study, 136 patients were divided into two groups: patients with positive specific immunoglobulin E (sIgE) and fungal finding (AFRS group), and patients with negative sIgE and positive fungal finding (FRS group). The study design included: anamnesis data, sIgE, eosinophil count and skin-prick test, rhinology and computerized tomography (CT) observation and mycological finding. Our results showed: (i) the prevalence in Serbia is: AFRS 1.3%, FRS 2.8%; (ii) 30.4% patients with sIgE+ had more often severe and recurrent chronic rhinosinusitis (CRS) (P = .005) and the presence of polyps (P = .025); (iii) 46.4% patients with sIgE+ had positive fungi on the sinonasal mucosa and were considered as AFRS; (iv) patients with AFRS had more frequent asthma (P = .024) and chronicity of CRS > 10 years (P = .000). The persistent fungal presence and prolonged duration of CRS could be a silent threat for the progression of inflammation and development of FRS. Lavage with hypertonic-NaCl should be included in the everyday hygiene routine in an effort to decrease fungal load and antigenic exposure. The presence of allergological parameters and better response to corticosteroid therapy in AFRS patients should be considered as crucial diagnostic criteria for AFRS.",
publisher = "Oxford Univ Press, Oxford",
journal = "Medical Mycology",
title = "Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis",
volume = "56",
number = "2",
pages = "162-171",
doi = "10.1093/mmy/myx032"
}
Barac, A., Stevanović, G., Pekmezović, M., Rakočević, Z., Stošović, R., Erović, B.,& Tomić-Spirić, V.. (2018). Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis. in Medical Mycology
Oxford Univ Press, Oxford., 56(2), 162-171.
https://doi.org/10.1093/mmy/myx032
Barac A, Stevanović G, Pekmezović M, Rakočević Z, Stošović R, Erović B, Tomić-Spirić V. Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis. in Medical Mycology. 2018;56(2):162-171.
doi:10.1093/mmy/myx032 .
Barac, Aleksandra, Stevanović, Goran, Pekmezović, Marina, Rakočević, Zoran, Stošović, Rajica, Erović, Boban, Tomić-Spirić, Vesna, "Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis" in Medical Mycology, 56, no. 2 (2018):162-171,
https://doi.org/10.1093/mmy/myx032 . .
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Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?

Barac, Aleksandra; Pekmezović, Marina; Rakočević, Zoran; Janović, Aleksa; Bracanović, Đurđa; Antić, Svetlana; Stevanović, G.; Tomić-Spirić, Vesna

(Wiley, Hoboken, 2017)

TY  - CONF
AU  - Barac, Aleksandra
AU  - Pekmezović, Marina
AU  - Rakočević, Zoran
AU  - Janović, Aleksa
AU  - Bracanović, Đurđa
AU  - Antić, Svetlana
AU  - Stevanović, G.
AU  - Tomić-Spirić, Vesna
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2221
PB  - Wiley, Hoboken
C3  - Allergy
T1  - Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?
VL  - 72
SP  - 206
EP  - 206
UR  - https://hdl.handle.net/21.15107/rcub_smile_2221
ER  - 
@conference{
author = "Barac, Aleksandra and Pekmezović, Marina and Rakočević, Zoran and Janović, Aleksa and Bracanović, Đurđa and Antić, Svetlana and Stevanović, G. and Tomić-Spirić, Vesna",
year = "2017",
publisher = "Wiley, Hoboken",
journal = "Allergy",
title = "Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?",
volume = "72",
pages = "206-206",
url = "https://hdl.handle.net/21.15107/rcub_smile_2221"
}
Barac, A., Pekmezović, M., Rakočević, Z., Janović, A., Bracanović, Đ., Antić, S., Stevanović, G.,& Tomić-Spirić, V.. (2017). Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?. in Allergy
Wiley, Hoboken., 72, 206-206.
https://hdl.handle.net/21.15107/rcub_smile_2221
Barac A, Pekmezović M, Rakočević Z, Janović A, Bracanović Đ, Antić S, Stevanović G, Tomić-Spirić V. Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?. in Allergy. 2017;72:206-206.
https://hdl.handle.net/21.15107/rcub_smile_2221 .
Barac, Aleksandra, Pekmezović, Marina, Rakočević, Zoran, Janović, Aleksa, Bracanović, Đurđa, Antić, Svetlana, Stevanović, G., Tomić-Spirić, Vesna, "Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?" in Allergy, 72 (2017):206-206,
https://hdl.handle.net/21.15107/rcub_smile_2221 .

Mathematical modeling and image analysis: possible clinical application in practice as a predictor of fungal rhinosinusitis

Barac, Aleksandra; Pekmezović, Marina; Rajković, Katarina; Rakočević, Zoran; Janović, Aleksa; Bracanović, Đurđa; Stošović, Rajica; Spirić, Tomić, V

(Wiley-Blackwell, Hoboken, 2016)

TY  - CONF
AU  - Barac, Aleksandra
AU  - Pekmezović, Marina
AU  - Rajković, Katarina
AU  - Rakočević, Zoran
AU  - Janović, Aleksa
AU  - Bracanović, Đurđa
AU  - Stošović, Rajica
AU  - Spirić, Tomić, V
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2085
PB  - Wiley-Blackwell, Hoboken
C3  - Allergy
T1  - Mathematical modeling and image analysis: possible clinical application in practice as a predictor of fungal rhinosinusitis
VL  - 71
SP  - 426
EP  - 426
UR  - https://hdl.handle.net/21.15107/rcub_smile_2085
ER  - 
@conference{
author = "Barac, Aleksandra and Pekmezović, Marina and Rajković, Katarina and Rakočević, Zoran and Janović, Aleksa and Bracanović, Đurđa and Stošović, Rajica and Spirić, Tomić, V",
year = "2016",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Allergy",
title = "Mathematical modeling and image analysis: possible clinical application in practice as a predictor of fungal rhinosinusitis",
volume = "71",
pages = "426-426",
url = "https://hdl.handle.net/21.15107/rcub_smile_2085"
}
Barac, A., Pekmezović, M., Rajković, K., Rakočević, Z., Janović, A., Bracanović, Đ., Stošović, R.,& Spirić, T. V.. (2016). Mathematical modeling and image analysis: possible clinical application in practice as a predictor of fungal rhinosinusitis. in Allergy
Wiley-Blackwell, Hoboken., 71, 426-426.
https://hdl.handle.net/21.15107/rcub_smile_2085
Barac A, Pekmezović M, Rajković K, Rakočević Z, Janović A, Bracanović Đ, Stošović R, Spirić TV. Mathematical modeling and image analysis: possible clinical application in practice as a predictor of fungal rhinosinusitis. in Allergy. 2016;71:426-426.
https://hdl.handle.net/21.15107/rcub_smile_2085 .
Barac, Aleksandra, Pekmezović, Marina, Rajković, Katarina, Rakočević, Zoran, Janović, Aleksa, Bracanović, Đurđa, Stošović, Rajica, Spirić, Tomić, V, "Mathematical modeling and image analysis: possible clinical application in practice as a predictor of fungal rhinosinusitis" in Allergy, 71 (2016):426-426,
https://hdl.handle.net/21.15107/rcub_smile_2085 .
1

Presence, species distribution, and density of Malassezia yeast in patients with seborrhoeic dermatitis - a community-based case-control study and review of literature

Barac, Aleksandra; Pekmezović, Marina; Milobratović, Danica; Otašević-Tasić, Suzana; Radunović, Milena; Arsić-Arsenijević, Valentina

(Wiley, Hoboken, 2015)

TY  - JOUR
AU  - Barac, Aleksandra
AU  - Pekmezović, Marina
AU  - Milobratović, Danica
AU  - Otašević-Tasić, Suzana
AU  - Radunović, Milena
AU  - Arsić-Arsenijević, Valentina
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2023
AB  - Malassezia yeast belongs to the normal cutaneous flora and under certain conditions it causes seborrhoeic dermatitis (SD). There is no culture-based study about the presence and density of the Malassezia in SD patients in Serbia. Aim was to show the presence, species distribution and density of Malassezia in patients with SD on lesional skin (LS) and non-lesional skin (NLS) and healthy controls (HC) and to compare data between Serbia and other countries. The study included 70 HC and 60 patients with SD in the study group (SG). Isolation, identification and examination of density of Malassezia colony-forming units from LS and NLS were performed. Malassezia was found more frequently in the SG than in HC, 90% and 60%, respectively (P lt 0.01). The most frequent isolates in SG on LS were M. slooffiae (26%), followed by M. globosa (17%) and M. sympodialis (17%). The yeast density was much higher on LS of SG than on NLS of SG or in the HC group (P lt 0.05). Higher density of Malassezia was shown on LS of SG than on NLS of SG and HC. M. slooffiae is the most prevalent species in SD patients in Serbia. This study demonstrated a positive relationship between severity of SD and presence of Malassezia spp.
PB  - Wiley, Hoboken
T2  - Mycoses
T1  - Presence, species distribution, and density of Malassezia yeast in patients with seborrhoeic dermatitis - a community-based case-control study and review of literature
VL  - 58
IS  - 2
SP  - 69
EP  - 75
DO  - 10.1111/myc.12276
ER  - 
@article{
author = "Barac, Aleksandra and Pekmezović, Marina and Milobratović, Danica and Otašević-Tasić, Suzana and Radunović, Milena and Arsić-Arsenijević, Valentina",
year = "2015",
abstract = "Malassezia yeast belongs to the normal cutaneous flora and under certain conditions it causes seborrhoeic dermatitis (SD). There is no culture-based study about the presence and density of the Malassezia in SD patients in Serbia. Aim was to show the presence, species distribution and density of Malassezia in patients with SD on lesional skin (LS) and non-lesional skin (NLS) and healthy controls (HC) and to compare data between Serbia and other countries. The study included 70 HC and 60 patients with SD in the study group (SG). Isolation, identification and examination of density of Malassezia colony-forming units from LS and NLS were performed. Malassezia was found more frequently in the SG than in HC, 90% and 60%, respectively (P lt 0.01). The most frequent isolates in SG on LS were M. slooffiae (26%), followed by M. globosa (17%) and M. sympodialis (17%). The yeast density was much higher on LS of SG than on NLS of SG or in the HC group (P lt 0.05). Higher density of Malassezia was shown on LS of SG than on NLS of SG and HC. M. slooffiae is the most prevalent species in SD patients in Serbia. This study demonstrated a positive relationship between severity of SD and presence of Malassezia spp.",
publisher = "Wiley, Hoboken",
journal = "Mycoses",
title = "Presence, species distribution, and density of Malassezia yeast in patients with seborrhoeic dermatitis - a community-based case-control study and review of literature",
volume = "58",
number = "2",
pages = "69-75",
doi = "10.1111/myc.12276"
}
Barac, A., Pekmezović, M., Milobratović, D., Otašević-Tasić, S., Radunović, M.,& Arsić-Arsenijević, V.. (2015). Presence, species distribution, and density of Malassezia yeast in patients with seborrhoeic dermatitis - a community-based case-control study and review of literature. in Mycoses
Wiley, Hoboken., 58(2), 69-75.
https://doi.org/10.1111/myc.12276
Barac A, Pekmezović M, Milobratović D, Otašević-Tasić S, Radunović M, Arsić-Arsenijević V. Presence, species distribution, and density of Malassezia yeast in patients with seborrhoeic dermatitis - a community-based case-control study and review of literature. in Mycoses. 2015;58(2):69-75.
doi:10.1111/myc.12276 .
Barac, Aleksandra, Pekmezović, Marina, Milobratović, Danica, Otašević-Tasić, Suzana, Radunović, Milena, Arsić-Arsenijević, Valentina, "Presence, species distribution, and density of Malassezia yeast in patients with seborrhoeic dermatitis - a community-based case-control study and review of literature" in Mycoses, 58, no. 2 (2015):69-75,
https://doi.org/10.1111/myc.12276 . .
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