Tomić-Spirić, Vesna

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orcid::0000-0002-7047-3538
  • Tomić-Spirić, Vesna (4)
Projects

Author's Bibliography

Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis

Barac, Aleksandra; Stevanović, Goran; Pekmezović, Marina; Rakočević, Zoran; Stošović, Rajica; Erović, Boban; Tomić-Spirić, Vesna

(Oxford Univ Press, Oxford, 2018)

TY  - JOUR
AU  - Barac, Aleksandra
AU  - Stevanović, Goran
AU  - Pekmezović, Marina
AU  - Rakočević, Zoran
AU  - Stošović, Rajica
AU  - Erović, Boban
AU  - Tomić-Spirić, Vesna
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2310
AB  - Dysbiosis of the microbiome on the airway mucosa leads to the development of chronic inflammatory and allergic disorders. The aim of this study was to consider the potential diagnostic criteria for allergic fungal rhinosinusitis (AFRS) and nonallergic fungal rhinosinusitis (FRS), and the role of fungal presence in an environment for the development of AFRS. In this study, 136 patients were divided into two groups: patients with positive specific immunoglobulin E (sIgE) and fungal finding (AFRS group), and patients with negative sIgE and positive fungal finding (FRS group). The study design included: anamnesis data, sIgE, eosinophil count and skin-prick test, rhinology and computerized tomography (CT) observation and mycological finding. Our results showed: (i) the prevalence in Serbia is: AFRS 1.3%, FRS 2.8%; (ii) 30.4% patients with sIgE+ had more often severe and recurrent chronic rhinosinusitis (CRS) (P = .005) and the presence of polyps (P = .025); (iii) 46.4% patients with sIgE+ had positive fungi on the sinonasal mucosa and were considered as AFRS; (iv) patients with AFRS had more frequent asthma (P = .024) and chronicity of CRS > 10 years (P = .000). The persistent fungal presence and prolonged duration of CRS could be a silent threat for the progression of inflammation and development of FRS. Lavage with hypertonic-NaCl should be included in the everyday hygiene routine in an effort to decrease fungal load and antigenic exposure. The presence of allergological parameters and better response to corticosteroid therapy in AFRS patients should be considered as crucial diagnostic criteria for AFRS.
PB  - Oxford Univ Press, Oxford
T2  - Medical Mycology
T1  - Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis
VL  - 56
IS  - 2
SP  - 162
EP  - 171
DO  - 10.1093/mmy/myx032
ER  - 
@article{
author = "Barac, Aleksandra and Stevanović, Goran and Pekmezović, Marina and Rakočević, Zoran and Stošović, Rajica and Erović, Boban and Tomić-Spirić, Vesna",
year = "2018",
abstract = "Dysbiosis of the microbiome on the airway mucosa leads to the development of chronic inflammatory and allergic disorders. The aim of this study was to consider the potential diagnostic criteria for allergic fungal rhinosinusitis (AFRS) and nonallergic fungal rhinosinusitis (FRS), and the role of fungal presence in an environment for the development of AFRS. In this study, 136 patients were divided into two groups: patients with positive specific immunoglobulin E (sIgE) and fungal finding (AFRS group), and patients with negative sIgE and positive fungal finding (FRS group). The study design included: anamnesis data, sIgE, eosinophil count and skin-prick test, rhinology and computerized tomography (CT) observation and mycological finding. Our results showed: (i) the prevalence in Serbia is: AFRS 1.3%, FRS 2.8%; (ii) 30.4% patients with sIgE+ had more often severe and recurrent chronic rhinosinusitis (CRS) (P = .005) and the presence of polyps (P = .025); (iii) 46.4% patients with sIgE+ had positive fungi on the sinonasal mucosa and were considered as AFRS; (iv) patients with AFRS had more frequent asthma (P = .024) and chronicity of CRS > 10 years (P = .000). The persistent fungal presence and prolonged duration of CRS could be a silent threat for the progression of inflammation and development of FRS. Lavage with hypertonic-NaCl should be included in the everyday hygiene routine in an effort to decrease fungal load and antigenic exposure. The presence of allergological parameters and better response to corticosteroid therapy in AFRS patients should be considered as crucial diagnostic criteria for AFRS.",
publisher = "Oxford Univ Press, Oxford",
journal = "Medical Mycology",
title = "Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis",
volume = "56",
number = "2",
pages = "162-171",
doi = "10.1093/mmy/myx032"
}
Barac, A., Stevanović, G., Pekmezović, M., Rakočević, Z., Stošović, R., Erović, B.,& Tomić-Spirić, V.. (2018). Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis. in Medical Mycology
Oxford Univ Press, Oxford., 56(2), 162-171.
https://doi.org/10.1093/mmy/myx032
Barac A, Stevanović G, Pekmezović M, Rakočević Z, Stošović R, Erović B, Tomić-Spirić V. Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis. in Medical Mycology. 2018;56(2):162-171.
doi:10.1093/mmy/myx032 .
Barac, Aleksandra, Stevanović, Goran, Pekmezović, Marina, Rakočević, Zoran, Stošović, Rajica, Erović, Boban, Tomić-Spirić, Vesna, "Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis" in Medical Mycology, 56, no. 2 (2018):162-171,
https://doi.org/10.1093/mmy/myx032 . .
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Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?

Barac, Aleksandra; Pekmezović, Marina; Rakočević, Zoran; Janović, Aleksa; Bracanović, Đurđa; Antić, Svetlana; Stevanović, G.; Tomić-Spirić, Vesna

(Wiley, Hoboken, 2017)

TY  - CONF
AU  - Barac, Aleksandra
AU  - Pekmezović, Marina
AU  - Rakočević, Zoran
AU  - Janović, Aleksa
AU  - Bracanović, Đurđa
AU  - Antić, Svetlana
AU  - Stevanović, G.
AU  - Tomić-Spirić, Vesna
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2221
PB  - Wiley, Hoboken
C3  - Allergy
T1  - Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?
VL  - 72
SP  - 206
EP  - 206
UR  - https://hdl.handle.net/21.15107/rcub_smile_2221
ER  - 
@conference{
author = "Barac, Aleksandra and Pekmezović, Marina and Rakočević, Zoran and Janović, Aleksa and Bracanović, Đurđa and Antić, Svetlana and Stevanović, G. and Tomić-Spirić, Vesna",
year = "2017",
publisher = "Wiley, Hoboken",
journal = "Allergy",
title = "Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?",
volume = "72",
pages = "206-206",
url = "https://hdl.handle.net/21.15107/rcub_smile_2221"
}
Barac, A., Pekmezović, M., Rakočević, Z., Janović, A., Bracanović, Đ., Antić, S., Stevanović, G.,& Tomić-Spirić, V.. (2017). Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?. in Allergy
Wiley, Hoboken., 72, 206-206.
https://hdl.handle.net/21.15107/rcub_smile_2221
Barac A, Pekmezović M, Rakočević Z, Janović A, Bracanović Đ, Antić S, Stevanović G, Tomić-Spirić V. Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?. in Allergy. 2017;72:206-206.
https://hdl.handle.net/21.15107/rcub_smile_2221 .
Barac, Aleksandra, Pekmezović, Marina, Rakočević, Zoran, Janović, Aleksa, Bracanović, Đurđa, Antić, Svetlana, Stevanović, G., Tomić-Spirić, Vesna, "Are there any specific signs of allergic fungal rhinosinusitis visible by computed tomography scan?" in Allergy, 72 (2017):206-206,
https://hdl.handle.net/21.15107/rcub_smile_2221 .

Diagnosis and prevention of non-allergic hypersensitivity reactions caused by iodinated contrast media-our expirience

Sojic-Rajcić, J.; Rasković, Sanvila; Tomić-Spirić, Vesna; Peri'-Popadić, Aleksandra; Đurić, Vojislav; Radulović, D.; Miličić, Biljana; Bogić, M.

(Wiley-Blackwell, Hoboken, 2016)

TY  - CONF
AU  - Sojic-Rajcić, J.
AU  - Rasković, Sanvila
AU  - Tomić-Spirić, Vesna
AU  - Peri'-Popadić, Aleksandra
AU  - Đurić, Vojislav
AU  - Radulović, D.
AU  - Miličić, Biljana
AU  - Bogić, M.
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2096
PB  - Wiley-Blackwell, Hoboken
C3  - Allergy
T1  - Diagnosis and prevention of non-allergic hypersensitivity reactions caused by iodinated contrast media-our expirience
VL  - 71
SP  - 51
EP  - 51
UR  - https://hdl.handle.net/21.15107/rcub_smile_2096
ER  - 
@conference{
author = "Sojic-Rajcić, J. and Rasković, Sanvila and Tomić-Spirić, Vesna and Peri'-Popadić, Aleksandra and Đurić, Vojislav and Radulović, D. and Miličić, Biljana and Bogić, M.",
year = "2016",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Allergy",
title = "Diagnosis and prevention of non-allergic hypersensitivity reactions caused by iodinated contrast media-our expirience",
volume = "71",
pages = "51-51",
url = "https://hdl.handle.net/21.15107/rcub_smile_2096"
}
Sojic-Rajcić, J., Rasković, S., Tomić-Spirić, V., Peri'-Popadić, A., Đurić, V., Radulović, D., Miličić, B.,& Bogić, M.. (2016). Diagnosis and prevention of non-allergic hypersensitivity reactions caused by iodinated contrast media-our expirience. in Allergy
Wiley-Blackwell, Hoboken., 71, 51-51.
https://hdl.handle.net/21.15107/rcub_smile_2096
Sojic-Rajcić J, Rasković S, Tomić-Spirić V, Peri'-Popadić A, Đurić V, Radulović D, Miličić B, Bogić M. Diagnosis and prevention of non-allergic hypersensitivity reactions caused by iodinated contrast media-our expirience. in Allergy. 2016;71:51-51.
https://hdl.handle.net/21.15107/rcub_smile_2096 .
Sojic-Rajcić, J., Rasković, Sanvila, Tomić-Spirić, Vesna, Peri'-Popadić, Aleksandra, Đurić, Vojislav, Radulović, D., Miličić, Biljana, Bogić, M., "Diagnosis and prevention of non-allergic hypersensitivity reactions caused by iodinated contrast media-our expirience" in Allergy, 71 (2016):51-51,
https://hdl.handle.net/21.15107/rcub_smile_2096 .

Efficacy of pastes containing CPP-ACP and CPP-ACFP in patients with Sjogren's syndrome

Perić, Tamara; Marković, Dejan; Petrović, Bojan; Radojević, Vesna J.; Todorović, Tatjana; Anđelski-Radičević, Biljana; Jančić-Heinemann, Radmila M.; Susić, Gordana; Peri'-Popadić, Aleksandra; Tomić-Spirić, Vesna

(Springer Heidelberg, Heidelberg, 2015)

TY  - JOUR
AU  - Perić, Tamara
AU  - Marković, Dejan
AU  - Petrović, Bojan
AU  - Radojević, Vesna J.
AU  - Todorović, Tatjana
AU  - Anđelski-Radičević, Biljana
AU  - Jančić-Heinemann, Radmila M.
AU  - Susić, Gordana
AU  - Peri'-Popadić, Aleksandra
AU  - Tomić-Spirić, Vesna
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1998
AB  - The purpose of this study was to evaluate efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) containing pastes among individuals with Sjogren's syndrome (SS). Thirty patients were randomised into three groups: CPP-ACP, CPP-ACFP, and 0.05 % NaF to be used two times a day during a 28-day experimental period. Saliva was analysed for flow rate, pH, buffering capacity and mineral concentrations. Dental plaque was examined for pH. Following the formation of artificial carious lesion, participants wore enamel slabs for an in situ remineralisation study. Remineralisation potential was examined using scanning electron microscope (SEM) and energy dispersive spectroscopic (EDS) technique. SE microphotographs were subsequently analysed for area, diameter, perimeter, roundness and the number of enamel defects and percentage of tooth surface affected by defects. At the end of the experimental period, a slight increase of salivary pH could have been observed. No differences in mineral composition of saliva were noted. The use of CPP-ACP and CPP-ACFP contributed to a significant rise of plaque pH. Image analysis revealed excessive reduction of defects' dimensions in the three experimental groups, and a decrease of the number of enamel defects in the CPP-ACP and CPP-ACFP groups. The EDS analysis did not show differences in Ca/P, Ca/O and P/O ratios in any of the treatment groups. CPP-ACP and CPP-ACFP hold promise as remineralising agents for patients with SS. Pastes containing CPP-ACP/CPP-ACFP show enhanced remineralisation potential compared with NaF mouthrinse in patients with SS.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Efficacy of pastes containing CPP-ACP and CPP-ACFP in patients with Sjogren's syndrome
VL  - 19
IS  - 9
SP  - 2153
EP  - 2165
DO  - 10.1007/s00784-015-1444-1
ER  - 
@article{
author = "Perić, Tamara and Marković, Dejan and Petrović, Bojan and Radojević, Vesna J. and Todorović, Tatjana and Anđelski-Radičević, Biljana and Jančić-Heinemann, Radmila M. and Susić, Gordana and Peri'-Popadić, Aleksandra and Tomić-Spirić, Vesna",
year = "2015",
abstract = "The purpose of this study was to evaluate efficacy of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACFP) containing pastes among individuals with Sjogren's syndrome (SS). Thirty patients were randomised into three groups: CPP-ACP, CPP-ACFP, and 0.05 % NaF to be used two times a day during a 28-day experimental period. Saliva was analysed for flow rate, pH, buffering capacity and mineral concentrations. Dental plaque was examined for pH. Following the formation of artificial carious lesion, participants wore enamel slabs for an in situ remineralisation study. Remineralisation potential was examined using scanning electron microscope (SEM) and energy dispersive spectroscopic (EDS) technique. SE microphotographs were subsequently analysed for area, diameter, perimeter, roundness and the number of enamel defects and percentage of tooth surface affected by defects. At the end of the experimental period, a slight increase of salivary pH could have been observed. No differences in mineral composition of saliva were noted. The use of CPP-ACP and CPP-ACFP contributed to a significant rise of plaque pH. Image analysis revealed excessive reduction of defects' dimensions in the three experimental groups, and a decrease of the number of enamel defects in the CPP-ACP and CPP-ACFP groups. The EDS analysis did not show differences in Ca/P, Ca/O and P/O ratios in any of the treatment groups. CPP-ACP and CPP-ACFP hold promise as remineralising agents for patients with SS. Pastes containing CPP-ACP/CPP-ACFP show enhanced remineralisation potential compared with NaF mouthrinse in patients with SS.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Efficacy of pastes containing CPP-ACP and CPP-ACFP in patients with Sjogren's syndrome",
volume = "19",
number = "9",
pages = "2153-2165",
doi = "10.1007/s00784-015-1444-1"
}
Perić, T., Marković, D., Petrović, B., Radojević, V. J., Todorović, T., Anđelski-Radičević, B., Jančić-Heinemann, R. M., Susić, G., Peri'-Popadić, A.,& Tomić-Spirić, V.. (2015). Efficacy of pastes containing CPP-ACP and CPP-ACFP in patients with Sjogren's syndrome. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 19(9), 2153-2165.
https://doi.org/10.1007/s00784-015-1444-1
Perić T, Marković D, Petrović B, Radojević VJ, Todorović T, Anđelski-Radičević B, Jančić-Heinemann RM, Susić G, Peri'-Popadić A, Tomić-Spirić V. Efficacy of pastes containing CPP-ACP and CPP-ACFP in patients with Sjogren's syndrome. in Clinical Oral Investigations. 2015;19(9):2153-2165.
doi:10.1007/s00784-015-1444-1 .
Perić, Tamara, Marković, Dejan, Petrović, Bojan, Radojević, Vesna J., Todorović, Tatjana, Anđelski-Radičević, Biljana, Jančić-Heinemann, Radmila M., Susić, Gordana, Peri'-Popadić, Aleksandra, Tomić-Spirić, Vesna, "Efficacy of pastes containing CPP-ACP and CPP-ACFP in patients with Sjogren's syndrome" in Clinical Oral Investigations, 19, no. 9 (2015):2153-2165,
https://doi.org/10.1007/s00784-015-1444-1 . .
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