TY  - JOUR
AU  - Đinić Krasavčević, Ana
AU  - Nikolić, Nadja
AU  - Mijailović, Iva
AU  - Čarkić, Jelena
AU  - Milinković, Iva
AU  - Janković, Saša
AU  - Aleksić, Zoran
AU  - Milašin, Jelena
PY  - 2021
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2568
AB  - Background and objective
Notch signalling cascade has recently been connected to alveolar bone resorption in periodontitis. Hence, the present cross‐sectional study aimed to analyze the expression of Notch signalling pathway (Notch 1, Notch 2, Jagged 1, Hes 1, Hey 1) and periodontitis‐related (tumor necrosis factor alpha‐ TNF‐α, interleukin 17‐IL‐17, receptor activator of nuclear factor‐kappa B ligand—RANKL, osteoprotegerin—OPG) molecules and correlate it with clinical parameters in aggressive (AP) and chronic (CP) periodontitis. Additionally, the aforementioned markers' expression was evaluated in periodontitis patients with different RANKL/OPG ratios.

Material and methods
Eighty patients were enrolled either in AP or CP group. Clinical attachment level (CAL), bleeding on probing (BOP), periodontal probing depth (PPD) and plaque index (PI) were recorded for each patient. Total RNA was extracted from gingival crevicular fluid samples. Relative gene expression of investigated markers was determined by reverse transcriptase‐real‐time polymerase chain reaction.

Results
Significantly higher values of PPD were observed in AP compared to CP (P = .010). Negative correlations between OPG and CAL, and OPG and PI, were found in AP (P = .045, P = .006, respectively), while Hey 1 and PI had a positive correlation (P = .049). In multivariate linear regression analysis, OPG and Notch 2 were predictors of CAL in AP group. TNF‐α and IL‐17 were higher in RANKL predominant than in OPG predominant cases (P = .007, P = .001, respectively). In RANKL predominant lesions Notch 1 and Jagged 1 were down‐regulated in AP compared to CP patients (P = .010, P = .025, respectively).

Conclusion
The present study demonstrated that changes in Notch 2 expression affected CAL in AP cases hence this molecule could be considered as a contributor to alveolar bone loss. In RANKL‐activated settings, the down‐regulation of Notch 1 might participate in more severe bone resorption in AP.
PB  - Wiley
T2  - Journal of Periodontal Research
T1  - Impact of Notch signalling molecules and bone resorption regulators on clinical parameters in periodontitis
VL  - 56
IS  - 1
SP  - 131
EP  - 138
DO  - 10.1111/jre.12801
ER  - 

@article{
author = "Đinić Krasavčević, Ana and Nikolić, Nadja and Mijailović, Iva and Čarkić, Jelena and Milinković, Iva and Janković, Saša and Aleksić, Zoran and Milašin, Jelena",
year = "2021",
abstract = "Background and objective
Notch signalling cascade has recently been connected to alveolar bone resorption in periodontitis. Hence, the present cross‐sectional study aimed to analyze the expression of Notch signalling pathway (Notch 1, Notch 2, Jagged 1, Hes 1, Hey 1) and periodontitis‐related (tumor necrosis factor alpha‐ TNF‐α, interleukin 17‐IL‐17, receptor activator of nuclear factor‐kappa B ligand—RANKL, osteoprotegerin—OPG) molecules and correlate it with clinical parameters in aggressive (AP) and chronic (CP) periodontitis. Additionally, the aforementioned markers' expression was evaluated in periodontitis patients with different RANKL/OPG ratios.

Material and methods
Eighty patients were enrolled either in AP or CP group. Clinical attachment level (CAL), bleeding on probing (BOP), periodontal probing depth (PPD) and plaque index (PI) were recorded for each patient. Total RNA was extracted from gingival crevicular fluid samples. Relative gene expression of investigated markers was determined by reverse transcriptase‐real‐time polymerase chain reaction.

Results
Significantly higher values of PPD were observed in AP compared to CP (P = .010). Negative correlations between OPG and CAL, and OPG and PI, were found in AP (P = .045, P = .006, respectively), while Hey 1 and PI had a positive correlation (P = .049). In multivariate linear regression analysis, OPG and Notch 2 were predictors of CAL in AP group. TNF‐α and IL‐17 were higher in RANKL predominant than in OPG predominant cases (P = .007, P = .001, respectively). In RANKL predominant lesions Notch 1 and Jagged 1 were down‐regulated in AP compared to CP patients (P = .010, P = .025, respectively).

Conclusion
The present study demonstrated that changes in Notch 2 expression affected CAL in AP cases hence this molecule could be considered as a contributor to alveolar bone loss. In RANKL‐activated settings, the down‐regulation of Notch 1 might participate in more severe bone resorption in AP.",
publisher = "Wiley",
journal = "Journal of Periodontal Research",
title = "Impact of Notch signalling molecules and bone resorption regulators on clinical parameters in periodontitis",
volume = "56",
number = "1",
pages = "131-138",
doi = "10.1111/jre.12801"
}

Đinić Krasavčević, A., Nikolić, N., Mijailović, I., Čarkić, J., Milinković, I., Janković, S., Aleksić, Z.,& Milašin, J.. (2021). Impact of Notch signalling molecules and bone resorption regulators on clinical parameters in periodontitis. in Journal of Periodontal Research
Wiley., 56(1), 131-138.
https://doi.org/10.1111/jre.12801

Đinić Krasavčević A, Nikolić N, Mijailović I, Čarkić J, Milinković I, Janković S, Aleksić Z, Milašin J. Impact of Notch signalling molecules and bone resorption regulators on clinical parameters in periodontitis. in Journal of Periodontal Research. 2021;56(1):131-138.
doi:10.1111/jre.12801 .

Đinić Krasavčević, Ana, Nikolić, Nadja, Mijailović, Iva, Čarkić, Jelena, Milinković, Iva, Janković, Saša, Aleksić, Zoran, Milašin, Jelena, "Impact of Notch signalling molecules and bone resorption regulators on clinical parameters in periodontitis" in Journal of Periodontal Research, 56, no. 1 (2021):131-138,
https://doi.org/10.1111/jre.12801 . .

TY  - JOUR
AU  - Vučković, Mila
AU  - Nikolić, Nadja
AU  - Milašin, Jelena
AU  - Đorđević, Vladan
AU  - Milinković, Iva
AU  - Asotić, Jasminka
AU  - Jezdić, Zoran
AU  - Janković, Saša
AU  - Aleksić, Zoran
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2525
AB  - Introduction/Objective. The objective of the study was to investigate whether there are differences in therapeutic effect between initial treatments of chronic periodontitis [scaling and root planning (SRP)] alone and SRP in conjunction with injectable platelet-rich fibrin (I-PRF) application, comparing clinical parameters after three months. Methods. Twenty-four patients with chronic periodontitis who had at least two sites with probing pocket depth (PPD) ≥ 5 mm on contralateral side participated in the study. Using a split-mouth design, the patients were treated with SRP + I-PRF (study group) or SRP only (control group). The clinical parameters, clinical attachment level (CAL), gingival margin level (GML), PPD, bleeding on probing, and plaque index, were recorded on both sides. Results. Compared to baseline, both treatment modalities demonstrated an improvement in investigated clinical parameters. The mean value of CAL was reduced from 1.97 ± 0.75 (0.25–3.31) to 1.07 ± 0.44 (0.12–1.78) in the study group, whereas it decreased from 1.81 ± 0.66 (0.42–2.96) to 1.48 ± 0.55 (0.22–2.30) in the control group. Similarly, the corresponding values for GML and PPD showed statistically significant difference between the groups (p = 0.040 and p = 0.006, respectively). Conclusion. Regardless the limited number of patients in the study, initial periodontal therapy in conjunction with injectable platelet-rich fibrin proved to display significant improvement in all clinical parameters compared to initial periodontal therapy alone.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis
VL  - 148
IS  - 5-6
SP  - 280
EP  - 285
DO  - 10.2298/SARH190925022V
ER  - 

@article{
author = "Vučković, Mila and Nikolić, Nadja and Milašin, Jelena and Đorđević, Vladan and Milinković, Iva and Asotić, Jasminka and Jezdić, Zoran and Janković, Saša and Aleksić, Zoran",
year = "2020",
abstract = "Introduction/Objective. The objective of the study was to investigate whether there are differences in therapeutic effect between initial treatments of chronic periodontitis [scaling and root planning (SRP)] alone and SRP in conjunction with injectable platelet-rich fibrin (I-PRF) application, comparing clinical parameters after three months. Methods. Twenty-four patients with chronic periodontitis who had at least two sites with probing pocket depth (PPD) ≥ 5 mm on contralateral side participated in the study. Using a split-mouth design, the patients were treated with SRP + I-PRF (study group) or SRP only (control group). The clinical parameters, clinical attachment level (CAL), gingival margin level (GML), PPD, bleeding on probing, and plaque index, were recorded on both sides. Results. Compared to baseline, both treatment modalities demonstrated an improvement in investigated clinical parameters. The mean value of CAL was reduced from 1.97 ± 0.75 (0.25–3.31) to 1.07 ± 0.44 (0.12–1.78) in the study group, whereas it decreased from 1.81 ± 0.66 (0.42–2.96) to 1.48 ± 0.55 (0.22–2.30) in the control group. Similarly, the corresponding values for GML and PPD showed statistically significant difference between the groups (p = 0.040 and p = 0.006, respectively). Conclusion. Regardless the limited number of patients in the study, initial periodontal therapy in conjunction with injectable platelet-rich fibrin proved to display significant improvement in all clinical parameters compared to initial periodontal therapy alone.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis",
volume = "148",
number = "5-6",
pages = "280-285",
doi = "10.2298/SARH190925022V"
}

Vučković, M., Nikolić, N., Milašin, J., Đorđević, V., Milinković, I., Asotić, J., Jezdić, Z., Janković, S.,& Aleksić, Z.. (2020). The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 148(5-6), 280-285.
https://doi.org/10.2298/SARH190925022V

Vučković M, Nikolić N, Milašin J, Đorđević V, Milinković I, Asotić J, Jezdić Z, Janković S, Aleksić Z. The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis. in Srpski arhiv za celokupno lekarstvo. 2020;148(5-6):280-285.
doi:10.2298/SARH190925022V .

Vučković, Mila, Nikolić, Nadja, Milašin, Jelena, Đorđević, Vladan, Milinković, Iva, Asotić, Jasminka, Jezdić, Zoran, Janković, Saša, Aleksić, Zoran, "The effect of injectable platelet-rich fibrin use in the initial treatment of chronic periodontitis" in Srpski arhiv za celokupno lekarstvo, 148, no. 5-6 (2020):280-285,
https://doi.org/10.2298/SARH190925022V . .

TY  - JOUR
AU  - Mijailović, Iva
AU  - Nikolić, Nadja
AU  - Đinić, Ana
AU  - Čarkić, Jelena
AU  - Milinković, Iva
AU  - Perić, Mina
AU  - Janković, Saša
AU  - Milašin, Jelena
AU  - Aleksić, Zoran
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2492
AB  - Background The exact mechanisms of bone resorption in periodontitis have not been fully elucidated. The aims of this study were to analyze the expression of Notch signaling molecules, bone remodeling mediators, and pro-inflammatory cytokines in periodontitis patients and to determine their potential correlations. Methods The study included 130 individuals: 40 with aggressive periodontitis (AP group), 40 with chronic periodontitis (CP group), and 50 periodontally healthy controls. Total RNA was extracted from gingival crevicular fluid samples and relative gene expression of investigated molecules (Notch 1, Notch 2, Jagged 1, Hes 1, Hey 1, TNF-alpha, IL-17, RANKL, and OPG) was determined by reverse transcriptase - real-time polymerase chain reaction (RT-qPCR). Results In AP group, a significant increase of Notch 2, TNF-alpha, IL-17 and RANKL and a significant decrease of Notch 1 and Jagged 1 expression were observed compared to control group (P = 0.023, P = 0.005, P = 0.030, and P = 0.001 P = 0.031 and P = 0.029, respectively). Notch 2 and RANKL were also overexpressed in CP group compared to controls (P = 0.001 and P = 0.011). Significant correlations were observed in AP group between expression levels of the analyzed genes. Conclusion The present findings implicate Notch 2 overexpression in the ethiopathogenesis of bone resorption in aggressive and chronic periodontitis. The down-regulation of Notch 1 and Jagged 1 and loss of their osteoprotective function might cause a more excessive osteoclast formation and contribute to greater osteolysis in aggressive periodontitis.
PB  - Wiley, Hoboken
T2  - Journal of Periodontology
T1  - The down-regulation of Notch 1 signaling contributes to the severity of bone loss in aggressive periodontitis
VL  - 91
IS  - 4
SP  - 554
EP  - 561
DO  - 10.1002/JPER.18-0755
ER  - 

@article{
author = "Mijailović, Iva and Nikolić, Nadja and Đinić, Ana and Čarkić, Jelena and Milinković, Iva and Perić, Mina and Janković, Saša and Milašin, Jelena and Aleksić, Zoran",
year = "2020",
abstract = "Background The exact mechanisms of bone resorption in periodontitis have not been fully elucidated. The aims of this study were to analyze the expression of Notch signaling molecules, bone remodeling mediators, and pro-inflammatory cytokines in periodontitis patients and to determine their potential correlations. Methods The study included 130 individuals: 40 with aggressive periodontitis (AP group), 40 with chronic periodontitis (CP group), and 50 periodontally healthy controls. Total RNA was extracted from gingival crevicular fluid samples and relative gene expression of investigated molecules (Notch 1, Notch 2, Jagged 1, Hes 1, Hey 1, TNF-alpha, IL-17, RANKL, and OPG) was determined by reverse transcriptase - real-time polymerase chain reaction (RT-qPCR). Results In AP group, a significant increase of Notch 2, TNF-alpha, IL-17 and RANKL and a significant decrease of Notch 1 and Jagged 1 expression were observed compared to control group (P = 0.023, P = 0.005, P = 0.030, and P = 0.001 P = 0.031 and P = 0.029, respectively). Notch 2 and RANKL were also overexpressed in CP group compared to controls (P = 0.001 and P = 0.011). Significant correlations were observed in AP group between expression levels of the analyzed genes. Conclusion The present findings implicate Notch 2 overexpression in the ethiopathogenesis of bone resorption in aggressive and chronic periodontitis. The down-regulation of Notch 1 and Jagged 1 and loss of their osteoprotective function might cause a more excessive osteoclast formation and contribute to greater osteolysis in aggressive periodontitis.",
publisher = "Wiley, Hoboken",
journal = "Journal of Periodontology",
title = "The down-regulation of Notch 1 signaling contributes to the severity of bone loss in aggressive periodontitis",
volume = "91",
number = "4",
pages = "554-561",
doi = "10.1002/JPER.18-0755"
}

Mijailović, I., Nikolić, N., Đinić, A., Čarkić, J., Milinković, I., Perić, M., Janković, S., Milašin, J.,& Aleksić, Z.. (2020). The down-regulation of Notch 1 signaling contributes to the severity of bone loss in aggressive periodontitis. in Journal of Periodontology
Wiley, Hoboken., 91(4), 554-561.
https://doi.org/10.1002/JPER.18-0755

Mijailović I, Nikolić N, Đinić A, Čarkić J, Milinković I, Perić M, Janković S, Milašin J, Aleksić Z. The down-regulation of Notch 1 signaling contributes to the severity of bone loss in aggressive periodontitis. in Journal of Periodontology. 2020;91(4):554-561.
doi:10.1002/JPER.18-0755 .

Mijailović, Iva, Nikolić, Nadja, Đinić, Ana, Čarkić, Jelena, Milinković, Iva, Perić, Mina, Janković, Saša, Milašin, Jelena, Aleksić, Zoran, "The down-regulation of Notch 1 signaling contributes to the severity of bone loss in aggressive periodontitis" in Journal of Periodontology, 91, no. 4 (2020):554-561,
https://doi.org/10.1002/JPER.18-0755 . .

TY  - JOUR
AU  - Ivanović, Tanja
AU  - Stojanović, Ljiljana
AU  - Ivanović, Dragan
AU  - Nikolić, Predrag
AU  - Milosavljević, Željko
AU  - Milinković, Iva
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2524
AB  - Introduction/Objective. Malocclusions are one of the most frequent disorders in dentistry, and pose a risk for the onset of caries and periodontal diseases. Fixed orthodontic treatment solves the problem of malocclusions; however, it requires simultaneous cooperation of the patients, parents, and dentists involved. The objective of this study is to examine the effects of fixed orthodontic therapy on the Streptococcus mutans and Lactobacillus spp. bacteria in saliva, the pH value, and buffering capacity of saliva. Methods. The research was carried out at the Faculty of Medicine in Foča, Department of Dentistry. The study included 100 respondents, aged 13 to 17 years. The respondents were divided into two groups: the study group (respondents wearing fixed braces) and the control group (respondents not subjected to fixed braces therapy). Saliva samples were taken from the respondents four, 12, and 18 weeks after the start of the orthodontic therapy. The study used the bacteria caries risk test (CRT) and CRT buffer (Ivoclar Vivadent). Results. The study showed an increased number of bacteria in saliva of the respondents during all three follow-up periods (χ2 test, p = 0.001). The largest numbers of the Streptococcus mutans and Lactobacillus spp. bacteria were found in week 12 of the therapy. Saliva pH value and buffering capacity of saliva increased statistically significantly in week 12 of the therapy (χ2 test, p = 0.001). Conclusion. Oral conditions in patients changed during the fixed orthodontic therapy: the number of bacteria increased, the pH value and buffering capacity of saliva changed. It was necessary to use preventive measures in order to avoid complications during the fixed orthodontic appliances therapy.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Effects of the fixed orthodontic therapy on biochemical and microbiological parameters of saliva
VL  - 148
IS  - 5-6
SP  - 270
EP  - 274
DO  - 10.2298/SARH190806016I
ER  - 

@article{
author = "Ivanović, Tanja and Stojanović, Ljiljana and Ivanović, Dragan and Nikolić, Predrag and Milosavljević, Željko and Milinković, Iva",
year = "2020",
abstract = "Introduction/Objective. Malocclusions are one of the most frequent disorders in dentistry, and pose a risk for the onset of caries and periodontal diseases. Fixed orthodontic treatment solves the problem of malocclusions; however, it requires simultaneous cooperation of the patients, parents, and dentists involved. The objective of this study is to examine the effects of fixed orthodontic therapy on the Streptococcus mutans and Lactobacillus spp. bacteria in saliva, the pH value, and buffering capacity of saliva. Methods. The research was carried out at the Faculty of Medicine in Foča, Department of Dentistry. The study included 100 respondents, aged 13 to 17 years. The respondents were divided into two groups: the study group (respondents wearing fixed braces) and the control group (respondents not subjected to fixed braces therapy). Saliva samples were taken from the respondents four, 12, and 18 weeks after the start of the orthodontic therapy. The study used the bacteria caries risk test (CRT) and CRT buffer (Ivoclar Vivadent). Results. The study showed an increased number of bacteria in saliva of the respondents during all three follow-up periods (χ2 test, p = 0.001). The largest numbers of the Streptococcus mutans and Lactobacillus spp. bacteria were found in week 12 of the therapy. Saliva pH value and buffering capacity of saliva increased statistically significantly in week 12 of the therapy (χ2 test, p = 0.001). Conclusion. Oral conditions in patients changed during the fixed orthodontic therapy: the number of bacteria increased, the pH value and buffering capacity of saliva changed. It was necessary to use preventive measures in order to avoid complications during the fixed orthodontic appliances therapy.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Effects of the fixed orthodontic therapy on biochemical and microbiological parameters of saliva",
volume = "148",
number = "5-6",
pages = "270-274",
doi = "10.2298/SARH190806016I"
}

Ivanović, T., Stojanović, L., Ivanović, D., Nikolić, P., Milosavljević, Ž.,& Milinković, I.. (2020). Effects of the fixed orthodontic therapy on biochemical and microbiological parameters of saliva. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 148(5-6), 270-274.
https://doi.org/10.2298/SARH190806016I

Ivanović T, Stojanović L, Ivanović D, Nikolić P, Milosavljević Ž, Milinković I. Effects of the fixed orthodontic therapy on biochemical and microbiological parameters of saliva. in Srpski arhiv za celokupno lekarstvo. 2020;148(5-6):270-274.
doi:10.2298/SARH190806016I .

Ivanović, Tanja, Stojanović, Ljiljana, Ivanović, Dragan, Nikolić, Predrag, Milosavljević, Željko, Milinković, Iva, "Effects of the fixed orthodontic therapy on biochemical and microbiological parameters of saliva" in Srpski arhiv za celokupno lekarstvo, 148, no. 5-6 (2020):270-274,
https://doi.org/10.2298/SARH190806016I . .

TY  - JOUR
AU  - Tovarović, Luka
AU  - Milinković, Iva
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2464
AB  - Introduction Gingival recession is the most common mucogingival anomaly, as well as the most frequent periodontal plastic surgery indication. The surgical procedure and healing of the wound result in scar formation, which impacts oral soft tissue aesthetics. The aim of this study was to evaluate the characteristics of a postsurgical scar after gingival recession treatment using the mucosal scarring index (MSI). Material and methods In accordance with the MSI, ten standardized and calibrated photographs of the postsurgical site, taken 3-6 months following the surgical procedure, were analyzed. That included the evaluation of six parameters: scar appearance, scar length, suture marks, contour, color, and overall appearance. 30 professionals divided into the three groups conducted the scar analysis: 10 dental students (S), 10 periodontology and oral medicine residents (SS) and 10 periodontal specialists (SP). Results the average MSI values showed the following results: S: 3.63 ± 2.71, SS: 3.63 ± 2.83 and SP: 3.12 ± 2.75. There was no difference between the MSI values obtained in the three groups (p=0.544). Conclusion Due to the similar MSI values among all the groups, a conclusion may be drawn that by the application of this index, the aesthetic evaluation of the postsurgical scar after the gingival recession treatment can be done in a fast and simple way. Further research based on a larger sample and various surgical procedures is necessary in order to confirm these statements.
AB  - Uvod Recesija gingive predstavlja najčešću mukogingivalnu anomaliju, kao i najčešću indikaciju za parodontalnu plastičnu hirurgiju. Kao rezultat hirurške intervencije i zarastanja rane dolazi do formiranja ožiljka, koji utiče na estetiku mekih oralnih tkiva. Cilj rada je bio evaluacija karakteristika postoperativnog ožiljka posle hirurške terapije recesije gingive primenom indeksa zarastanja oralnih tkiva (IZO). Materijal i metode Deset standardizovanih i kalibrisanih fotografija posthirurške regije napravljenih tri do šest meseci posle hirurške intervencije analizirano je u skladu sa IZO, koji obuhvata procenu šest parametara: prisustvo ožiljka, dužinu ožiljka, tragove šavova, odnos prema okolnom tkivu, boju, kao i opšti utisak. Procenu ožiljka vršilo je 30 stručnih lica podeljenih u tri grupe: 10 studenata osnovnih studija (S), 10 studenata specijalističkih studija iz parodontologije i oralne medicine (SS) i 10 specijalista parodontologije i oralne medicine (SP). Rezultati Srednje vrednosti IZO po grupama pokazale su sledeće vrednosti: S: 3,63 ± 2,71, SS: 3,63 ± 2,83 i SP: 3,12 ± 2,75. Vrednosti IZO između tri grupe nisu pokazale statistički značajnu razliku (p = 0,544). Zaključak S obzirom na slične vrednosti IZO kod svih grupa ispitivača, može se zaključiti da se primenom ovog indeksa na brz i jednostavan način može vršiti estetska evaluacija postoperativnog ožiljka posle terapije recesije gingive. Potrebna su dalja istraživanja na većem uzorku pacijenata i kod različitih hirurških intervencija u cilju potvrde ovih tvrdnji.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Evaluation of mucosal scar characteristics after periodontal plastic surgery
T1  - Evaluacija karakteristika mukoznog ožiljka posle parodontalnih plastičnohirurških intervencija
VL  - 66
IS  - 2
SP  - 66
EP  - 71
DO  - 10.2478/sdj-2019-0007
ER  - 

@article{
author = "Tovarović, Luka and Milinković, Iva",
year = "2019",
abstract = "Introduction Gingival recession is the most common mucogingival anomaly, as well as the most frequent periodontal plastic surgery indication. The surgical procedure and healing of the wound result in scar formation, which impacts oral soft tissue aesthetics. The aim of this study was to evaluate the characteristics of a postsurgical scar after gingival recession treatment using the mucosal scarring index (MSI). Material and methods In accordance with the MSI, ten standardized and calibrated photographs of the postsurgical site, taken 3-6 months following the surgical procedure, were analyzed. That included the evaluation of six parameters: scar appearance, scar length, suture marks, contour, color, and overall appearance. 30 professionals divided into the three groups conducted the scar analysis: 10 dental students (S), 10 periodontology and oral medicine residents (SS) and 10 periodontal specialists (SP). Results the average MSI values showed the following results: S: 3.63 ± 2.71, SS: 3.63 ± 2.83 and SP: 3.12 ± 2.75. There was no difference between the MSI values obtained in the three groups (p=0.544). Conclusion Due to the similar MSI values among all the groups, a conclusion may be drawn that by the application of this index, the aesthetic evaluation of the postsurgical scar after the gingival recession treatment can be done in a fast and simple way. Further research based on a larger sample and various surgical procedures is necessary in order to confirm these statements., Uvod Recesija gingive predstavlja najčešću mukogingivalnu anomaliju, kao i najčešću indikaciju za parodontalnu plastičnu hirurgiju. Kao rezultat hirurške intervencije i zarastanja rane dolazi do formiranja ožiljka, koji utiče na estetiku mekih oralnih tkiva. Cilj rada je bio evaluacija karakteristika postoperativnog ožiljka posle hirurške terapije recesije gingive primenom indeksa zarastanja oralnih tkiva (IZO). Materijal i metode Deset standardizovanih i kalibrisanih fotografija posthirurške regije napravljenih tri do šest meseci posle hirurške intervencije analizirano je u skladu sa IZO, koji obuhvata procenu šest parametara: prisustvo ožiljka, dužinu ožiljka, tragove šavova, odnos prema okolnom tkivu, boju, kao i opšti utisak. Procenu ožiljka vršilo je 30 stručnih lica podeljenih u tri grupe: 10 studenata osnovnih studija (S), 10 studenata specijalističkih studija iz parodontologije i oralne medicine (SS) i 10 specijalista parodontologije i oralne medicine (SP). Rezultati Srednje vrednosti IZO po grupama pokazale su sledeće vrednosti: S: 3,63 ± 2,71, SS: 3,63 ± 2,83 i SP: 3,12 ± 2,75. Vrednosti IZO između tri grupe nisu pokazale statistički značajnu razliku (p = 0,544). Zaključak S obzirom na slične vrednosti IZO kod svih grupa ispitivača, može se zaključiti da se primenom ovog indeksa na brz i jednostavan način može vršiti estetska evaluacija postoperativnog ožiljka posle terapije recesije gingive. Potrebna su dalja istraživanja na većem uzorku pacijenata i kod različitih hirurških intervencija u cilju potvrde ovih tvrdnji.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Evaluation of mucosal scar characteristics after periodontal plastic surgery, Evaluacija karakteristika mukoznog ožiljka posle parodontalnih plastičnohirurških intervencija",
volume = "66",
number = "2",
pages = "66-71",
doi = "10.2478/sdj-2019-0007"
}

Tovarović, L.,& Milinković, I.. (2019). Evaluation of mucosal scar characteristics after periodontal plastic surgery. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 66(2), 66-71.
https://doi.org/10.2478/sdj-2019-0007

Tovarović L, Milinković I. Evaluation of mucosal scar characteristics after periodontal plastic surgery. in Stomatološki glasnik Srbije. 2019;66(2):66-71.
doi:10.2478/sdj-2019-0007 .

Tovarović, Luka, Milinković, Iva, "Evaluation of mucosal scar characteristics after periodontal plastic surgery" in Stomatološki glasnik Srbije, 66, no. 2 (2019):66-71,
https://doi.org/10.2478/sdj-2019-0007 . .

TY  - JOUR
AU  - Milinković, Iva
AU  - Ivanović, Tanja
AU  - Nikolić, Predrag
AU  - Stojanović, Ljiljana
AU  - Milosavljević, Željko
AU  - Samardžija-Hrisa, Jovana
AU  - Šarac, Aleksandra
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2374
AB  - Introduction Caries and orthodontic anomalies in school-age children lead to disturbed aesthetics, oral functions (chewing, swallowing, and speech), predisposition to trauma and the onset of periodontal diseases. The aim was to assess dental health and frequency of orthodontic anomalies in children aged 8-9 years in the municipality of Foča. Methods The research was conducted in the primary school Sveti Sava in Foča, where the total of 112 children age 8-9 years were examined. An informed consent was obtained from parents and school director for each student. Dental examination was performed using standard dental method, a mirror and a probe under artificial lighting. Children received instructions on proper nutrition, oral hygiene, tooth protection and elimination of bad habits. Results Among 112 examined boys and girls of selected ages, very high person caries index (PCI) was found (78.57%). A total of 548 caries affected teeth were found (boys 331 (24.62%), girls 217 (16.14%) (p  lt 0.05)). Fifty-nine children had caries lesions on permanent teeth (boys 39 (2.9%), girls 20 (1.5%) (p  lt 0.05)). Sagital abnormalities of the bite were present in 39 (34.82%) children, while 38 (33.92%) anomalies were related to vertical bite irregularities, 10 (8.92%) of them had open bite and 28 subjects (25%) had deep bite (p> 0.05). Conclusion Large number of teeth was affected with caries lesions (548) in eighth-year-olds, while orthodontic anomalies, mostly sagital abnormalities of bite were found in 39 subjects.
AB  - Uvod Karijes i ortodontske anomalije kod dece školskog uzrasta dovode do narušene estetike, poremećaja oralnih funkcija (žvakanje, gutanje i govor), povećane sklonosti nastanku trauma i nastanku parodontalnih bolesti. Cilj ovog rada je bio da se provere dentalno zdravlje i učestalost ortodontskih anomalija kod dece uzrasta 8-9 godina na području opštine Foča. Metode Istraživanje je sprovedeno u Osnovnoj školi 'Sveti Sava' u Foči, gde je pregledano ukupno 112 dece uzrasta 8-9 godina. Kod svakog učenika za koga je postojao informativni pristanak roditelja i direktora škole obavljen je stomatološki pregled standardnom stomatološkom metodom, ogledalom i sondom uz korišćenje veštačkog osvetljenja. Deca su dobila upute o pravilnoj ishrani, higijeni, zaštiti zuba i eliminaciji loših navika. Rezultati Kod 112 pregledanih dečaka i devojčica odabranih uzrasta utvrđen je veoma visok karijes indeks osoba (KIo) - od 78,57%. Ukupno je pronađeno 548 karijesom zahvaćenih mlečnih zuba (dečaci 331 (24,62%); devojčice 217 (16,14%) (p  lt  0,05)). Kod ukupno 59 ispitanika pronađen je karijes stalnih zuba (dečaci 39 (2,9%); devojčice 20 (1,5%) (p  lt  0,05)). Sagitalne nepravilnosti zagrižaja su bile zastupljene kod ukupno 39 (34,82%) dece, dok se ukupno 38 (33,92%) anomalija odnosilo na vertikalne nepravilnosti zagrižaja, pri čemu je 10 (8,92%) ispitanika imalo otvoren zagrižaj, a 28 ispitanika (25%) dubok zagrižaj (p > 0,05). Zaključak Kod osmogodišnjaka je pronađen veliki broj karijesom zahvaćenih mlečnih zuba (548) i velika zastupljenost ortodontskih anomalija, od kojih su najzastupljenije sagitalne nepravilnosti zagrižaja, koje su pronađene kod 39 ispitanika. .
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Frequency of malocclusion and condition of dental health among eight-year-old children in the municipality of Foča
T1  - Učestalost malokluzija i stanje dentalnog zdravlja kod osmogodišnjaka na području opštine Foča
VL  - 65
IS  - 3
SP  - 133
EP  - 139
DO  - 10.2478/sdj-2018-0013
ER  - 

@article{
author = "Milinković, Iva and Ivanović, Tanja and Nikolić, Predrag and Stojanović, Ljiljana and Milosavljević, Željko and Samardžija-Hrisa, Jovana and Šarac, Aleksandra",
year = "2018",
abstract = "Introduction Caries and orthodontic anomalies in school-age children lead to disturbed aesthetics, oral functions (chewing, swallowing, and speech), predisposition to trauma and the onset of periodontal diseases. The aim was to assess dental health and frequency of orthodontic anomalies in children aged 8-9 years in the municipality of Foča. Methods The research was conducted in the primary school Sveti Sava in Foča, where the total of 112 children age 8-9 years were examined. An informed consent was obtained from parents and school director for each student. Dental examination was performed using standard dental method, a mirror and a probe under artificial lighting. Children received instructions on proper nutrition, oral hygiene, tooth protection and elimination of bad habits. Results Among 112 examined boys and girls of selected ages, very high person caries index (PCI) was found (78.57%). A total of 548 caries affected teeth were found (boys 331 (24.62%), girls 217 (16.14%) (p  lt 0.05)). Fifty-nine children had caries lesions on permanent teeth (boys 39 (2.9%), girls 20 (1.5%) (p  lt 0.05)). Sagital abnormalities of the bite were present in 39 (34.82%) children, while 38 (33.92%) anomalies were related to vertical bite irregularities, 10 (8.92%) of them had open bite and 28 subjects (25%) had deep bite (p> 0.05). Conclusion Large number of teeth was affected with caries lesions (548) in eighth-year-olds, while orthodontic anomalies, mostly sagital abnormalities of bite were found in 39 subjects., Uvod Karijes i ortodontske anomalije kod dece školskog uzrasta dovode do narušene estetike, poremećaja oralnih funkcija (žvakanje, gutanje i govor), povećane sklonosti nastanku trauma i nastanku parodontalnih bolesti. Cilj ovog rada je bio da se provere dentalno zdravlje i učestalost ortodontskih anomalija kod dece uzrasta 8-9 godina na području opštine Foča. Metode Istraživanje je sprovedeno u Osnovnoj školi 'Sveti Sava' u Foči, gde je pregledano ukupno 112 dece uzrasta 8-9 godina. Kod svakog učenika za koga je postojao informativni pristanak roditelja i direktora škole obavljen je stomatološki pregled standardnom stomatološkom metodom, ogledalom i sondom uz korišćenje veštačkog osvetljenja. Deca su dobila upute o pravilnoj ishrani, higijeni, zaštiti zuba i eliminaciji loših navika. Rezultati Kod 112 pregledanih dečaka i devojčica odabranih uzrasta utvrđen je veoma visok karijes indeks osoba (KIo) - od 78,57%. Ukupno je pronađeno 548 karijesom zahvaćenih mlečnih zuba (dečaci 331 (24,62%); devojčice 217 (16,14%) (p  lt  0,05)). Kod ukupno 59 ispitanika pronađen je karijes stalnih zuba (dečaci 39 (2,9%); devojčice 20 (1,5%) (p  lt  0,05)). Sagitalne nepravilnosti zagrižaja su bile zastupljene kod ukupno 39 (34,82%) dece, dok se ukupno 38 (33,92%) anomalija odnosilo na vertikalne nepravilnosti zagrižaja, pri čemu je 10 (8,92%) ispitanika imalo otvoren zagrižaj, a 28 ispitanika (25%) dubok zagrižaj (p > 0,05). Zaključak Kod osmogodišnjaka je pronađen veliki broj karijesom zahvaćenih mlečnih zuba (548) i velika zastupljenost ortodontskih anomalija, od kojih su najzastupljenije sagitalne nepravilnosti zagrižaja, koje su pronađene kod 39 ispitanika. .",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Frequency of malocclusion and condition of dental health among eight-year-old children in the municipality of Foča, Učestalost malokluzija i stanje dentalnog zdravlja kod osmogodišnjaka na području opštine Foča",
volume = "65",
number = "3",
pages = "133-139",
doi = "10.2478/sdj-2018-0013"
}

Milinković, I., Ivanović, T., Nikolić, P., Stojanović, L., Milosavljević, Ž., Samardžija-Hrisa, J.,& Šarac, A.. (2018). Frequency of malocclusion and condition of dental health among eight-year-old children in the municipality of Foča. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 65(3), 133-139.
https://doi.org/10.2478/sdj-2018-0013

Milinković I, Ivanović T, Nikolić P, Stojanović L, Milosavljević Ž, Samardžija-Hrisa J, Šarac A. Frequency of malocclusion and condition of dental health among eight-year-old children in the municipality of Foča. in Stomatološki glasnik Srbije. 2018;65(3):133-139.
doi:10.2478/sdj-2018-0013 .

Milinković, Iva, Ivanović, Tanja, Nikolić, Predrag, Stojanović, Ljiljana, Milosavljević, Željko, Samardžija-Hrisa, Jovana, Šarac, Aleksandra, "Frequency of malocclusion and condition of dental health among eight-year-old children in the municipality of Foča" in Stomatološki glasnik Srbije, 65, no. 3 (2018):133-139,
https://doi.org/10.2478/sdj-2018-0013 . .

TY  - JOUR
AU  - Van Assche, Nele
AU  - Fickl, Stefan
AU  - Francisco, Helena
AU  - Gurzawska, Katarzyna
AU  - Milinković, Iva
AU  - Navarro, Jose M.
AU  - Torsello, Ferruccio
AU  - Thoma, Daniel S.
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2302
AB  - BackgroundDuring the third Summer Camp of European Association of Osseointegration (EAO), 40 junior representatives from various European societies and associations were brought together to discuss and explore the following topics in Implant Dentistry in the next 10years: (I) certification, (II) societies and associations, (III) continuing education, and (IV) innovations. AimsThe aims of all working groups were to identify and outline the present situation in the area of the selected topic and to propose improvements and innovations to be implemented in the following 10years. Materials and methodsFour different groups were assigned randomly to one of the four working units. The method to discuss the selected topics was World Cafe. The summaries of four topics were then given to all participants for peer review. Results and conclusionsAll four groups presented the conclusions and guidelines accordingly: (I) The recognition for Implant Dentistry and accreditation of training programs would lead to an improvement of the quality of care to the benefit of the patients; (II) Dental associations and societies have to continuously improve communication to meet needs of dental students, professionals, and patients (III) European Dental Board should be installed and become responsible for continue dental education; (IV) dental engineering, peri-implant diseases, and digital workflow in dentistry currently have limited tools that do not guarantee predictable results.
PB  - Wiley, Hoboken
T2  - Clinical Oral Implants Research
T1  - Guidelines for development of Implant Dentistry in the next 10years regarding innovation, education, certification, and associations
VL  - 29
IS  - 6
SP  - 568
EP  - 575
DO  - 10.1111/clr.13154
ER  - 

@article{
author = "Van Assche, Nele and Fickl, Stefan and Francisco, Helena and Gurzawska, Katarzyna and Milinković, Iva and Navarro, Jose M. and Torsello, Ferruccio and Thoma, Daniel S.",
year = "2018",
abstract = "BackgroundDuring the third Summer Camp of European Association of Osseointegration (EAO), 40 junior representatives from various European societies and associations were brought together to discuss and explore the following topics in Implant Dentistry in the next 10years: (I) certification, (II) societies and associations, (III) continuing education, and (IV) innovations. AimsThe aims of all working groups were to identify and outline the present situation in the area of the selected topic and to propose improvements and innovations to be implemented in the following 10years. Materials and methodsFour different groups were assigned randomly to one of the four working units. The method to discuss the selected topics was World Cafe. The summaries of four topics were then given to all participants for peer review. Results and conclusionsAll four groups presented the conclusions and guidelines accordingly: (I) The recognition for Implant Dentistry and accreditation of training programs would lead to an improvement of the quality of care to the benefit of the patients; (II) Dental associations and societies have to continuously improve communication to meet needs of dental students, professionals, and patients (III) European Dental Board should be installed and become responsible for continue dental education; (IV) dental engineering, peri-implant diseases, and digital workflow in dentistry currently have limited tools that do not guarantee predictable results.",
publisher = "Wiley, Hoboken",
journal = "Clinical Oral Implants Research",
title = "Guidelines for development of Implant Dentistry in the next 10years regarding innovation, education, certification, and associations",
volume = "29",
number = "6",
pages = "568-575",
doi = "10.1111/clr.13154"
}

Van Assche, N., Fickl, S., Francisco, H., Gurzawska, K., Milinković, I., Navarro, J. M., Torsello, F.,& Thoma, D. S.. (2018). Guidelines for development of Implant Dentistry in the next 10years regarding innovation, education, certification, and associations. in Clinical Oral Implants Research
Wiley, Hoboken., 29(6), 568-575.
https://doi.org/10.1111/clr.13154

Van Assche N, Fickl S, Francisco H, Gurzawska K, Milinković I, Navarro JM, Torsello F, Thoma DS. Guidelines for development of Implant Dentistry in the next 10years regarding innovation, education, certification, and associations. in Clinical Oral Implants Research. 2018;29(6):568-575.
doi:10.1111/clr.13154 .

Van Assche, Nele, Fickl, Stefan, Francisco, Helena, Gurzawska, Katarzyna, Milinković, Iva, Navarro, Jose M., Torsello, Ferruccio, Thoma, Daniel S., "Guidelines for development of Implant Dentistry in the next 10years regarding innovation, education, certification, and associations" in Clinical Oral Implants Research, 29, no. 6 (2018):568-575,
https://doi.org/10.1111/clr.13154 . .

TY  - JOUR
AU  - Schliephake, Henning
AU  - Sicilia, Alberto
AU  - Al Nawas, Bilal
AU  - Donos, Nikos
AU  - Gruber, Reinhard
AU  - Jepsen, Soren
AU  - Milinković, Iva
AU  - Mombelli, Andrea
AU  - Navarro, Jose M.
AU  - Quirynen, Marc
AU  - Rocchietta, Isabella
AU  - Schiodt, Morten
AU  - Schou, Soren
AU  - Stahli, Alexandra
AU  - Stavropoulos, Andreas
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2283
AB  - Objectives: The task of this working group was to update the knowledge about the use of drugs and biologicals affecting healing of soft tissue and bone during implant treatment or procedures associated with it. Moreover, the impact of titanium particles and biocorrosion on complications and implant survival has been analysed. Materials and Methods: The literature in the areas of interest (platelet concentrates, antiresorptive drugs as well as implant-host interaction) was screened using systematic reviews for the former two areas, whereas a narrative critical review was performed for the latter topic. Two manuscripts on platelet concentrates, one manuscript on antiresorptive drugs and one manuscript on the effects of biocorrosion, were presented for group analysis with subsequent discussion in the plenum and final consensus approval. Results: Results and conclusions of the individual reviews of the three topics are presented in the respective papers. Conclusions of the group on strengths and weaknesses of available evidence as well as consensus statements and directions for further research are provided in this study. The following papers were subject to group discussions and formed the basis for the consensus statements: Stahli A, Strauss FJ, Gruber R. (2018) The use of platelet-rich-plasma to enhance the outcomes of implant-related therapies: a systematic review Strauss FJ, Stahli A, Gruber R. (2018) The use of platelet-rich-fibrin to enhance the outcomes of implant-related therapies: a systematic review Mombelli A, Hashim D, Cionca N. (2018) What is the impact of titanium particles and bio-corrosion on implant survival and complications? A critical review Stavropoulos A, Bertl K, Pietschmann P, Pandis N, Morten Schiodt, Klinge B. (2018) The effect of antiresorptive drugs on implant therapy: a systematic review.
PB  - Wiley, Hoboken
T2  - Clinical Oral Implants Research
T1  - Drugs and diseases: Summary and consensus statements of group 1. The 5th EAO Consensus Conference 2018
VL  - 29
SP  - 93
EP  - 99
DO  - 10.1111/clr.13270
ER  - 

@article{
author = "Schliephake, Henning and Sicilia, Alberto and Al Nawas, Bilal and Donos, Nikos and Gruber, Reinhard and Jepsen, Soren and Milinković, Iva and Mombelli, Andrea and Navarro, Jose M. and Quirynen, Marc and Rocchietta, Isabella and Schiodt, Morten and Schou, Soren and Stahli, Alexandra and Stavropoulos, Andreas",
year = "2018",
abstract = "Objectives: The task of this working group was to update the knowledge about the use of drugs and biologicals affecting healing of soft tissue and bone during implant treatment or procedures associated with it. Moreover, the impact of titanium particles and biocorrosion on complications and implant survival has been analysed. Materials and Methods: The literature in the areas of interest (platelet concentrates, antiresorptive drugs as well as implant-host interaction) was screened using systematic reviews for the former two areas, whereas a narrative critical review was performed for the latter topic. Two manuscripts on platelet concentrates, one manuscript on antiresorptive drugs and one manuscript on the effects of biocorrosion, were presented for group analysis with subsequent discussion in the plenum and final consensus approval. Results: Results and conclusions of the individual reviews of the three topics are presented in the respective papers. Conclusions of the group on strengths and weaknesses of available evidence as well as consensus statements and directions for further research are provided in this study. The following papers were subject to group discussions and formed the basis for the consensus statements: Stahli A, Strauss FJ, Gruber R. (2018) The use of platelet-rich-plasma to enhance the outcomes of implant-related therapies: a systematic review Strauss FJ, Stahli A, Gruber R. (2018) The use of platelet-rich-fibrin to enhance the outcomes of implant-related therapies: a systematic review Mombelli A, Hashim D, Cionca N. (2018) What is the impact of titanium particles and bio-corrosion on implant survival and complications? A critical review Stavropoulos A, Bertl K, Pietschmann P, Pandis N, Morten Schiodt, Klinge B. (2018) The effect of antiresorptive drugs on implant therapy: a systematic review.",
publisher = "Wiley, Hoboken",
journal = "Clinical Oral Implants Research",
title = "Drugs and diseases: Summary and consensus statements of group 1. The 5th EAO Consensus Conference 2018",
volume = "29",
pages = "93-99",
doi = "10.1111/clr.13270"
}

Schliephake, H., Sicilia, A., Al Nawas, B., Donos, N., Gruber, R., Jepsen, S., Milinković, I., Mombelli, A., Navarro, J. M., Quirynen, M., Rocchietta, I., Schiodt, M., Schou, S., Stahli, A.,& Stavropoulos, A.. (2018). Drugs and diseases: Summary and consensus statements of group 1. The 5th EAO Consensus Conference 2018. in Clinical Oral Implants Research
Wiley, Hoboken., 29, 93-99.
https://doi.org/10.1111/clr.13270

Schliephake H, Sicilia A, Al Nawas B, Donos N, Gruber R, Jepsen S, Milinković I, Mombelli A, Navarro JM, Quirynen M, Rocchietta I, Schiodt M, Schou S, Stahli A, Stavropoulos A. Drugs and diseases: Summary and consensus statements of group 1. The 5th EAO Consensus Conference 2018. in Clinical Oral Implants Research. 2018;29:93-99.
doi:10.1111/clr.13270 .

Schliephake, Henning, Sicilia, Alberto, Al Nawas, Bilal, Donos, Nikos, Gruber, Reinhard, Jepsen, Soren, Milinković, Iva, Mombelli, Andrea, Navarro, Jose M., Quirynen, Marc, Rocchietta, Isabella, Schiodt, Morten, Schou, Soren, Stahli, Alexandra, Stavropoulos, Andreas, "Drugs and diseases: Summary and consensus statements of group 1. The 5th EAO Consensus Conference 2018" in Clinical Oral Implants Research, 29 (2018):93-99,
https://doi.org/10.1111/clr.13270 . .

TY  - JOUR
AU  - Milinković, Iva
AU  - Aleksić, Zoran
AU  - Janković, Saša
AU  - Popović, O.
AU  - Bajić, Miljan
AU  - Čakić, Saša
AU  - Leković, Vojislav
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1977
AB  - Background and ObjectiveGingival recession is defined as soft and hard tissue displacement resulting in root surface exposure. The optimal outcome of gingival recession treatment is complete, predictable and long-lasting root coverage with a significant level of tissue regeneration. Tissue engineering, which applies active regeneration principles, presents the contemporary treatment approach in the restitution and regeneration of lost tissues. The objective of the present study was to evaluate and compare the clinical results of application of an autologous fibroblast cell culture (AFCC) on a collagen matrix and a connective tissue graft (CTG) placed under a coronally advanced flap (CAF), in the treatment of single and multiple gingival recessions. Material and MethodsEighteen patients from the Department of Periodontology, School of Dentistry, University of Belgrade, were randomly enrolled in this study. Inclusion criteria were the bilateral presence of Miller Class I or II single or multiple maxillary gingival recessions. A split-mouth design was used in the study. The experimental group was treated with AFCC on a collagen scaffold, which was placed under a CAF. The control group received a combination of CTG and CAF. Clinical parameters such as gingival recession coverage, keratinized tissue width, clinical attachment level and gingival index were recorded at baseline and at 12mo postoperatively. The oral hygiene level was assessed by plaque index evaluation. Postoperative healing was evaluated through the healing index, recorded 1, 2 and 3wk postoperatively. The final esthetic outcome was assessed using the mean root coverage esthetic score (RES). ResultsStatistically significant improvement of all parameters assessed was found compared with baseline. A statistically significant difference between groups was observed only in keratinized tissue width. Greater keratinized tissue width is still obtained with the use of CTG. Regarding the tissue-healing results, no statistically significant difference was achieved. The RES results were similar for both groups. ConclusionsWithin the limitations of the present study, both procedures proved to be efficient in gingival recession treatment. AFCC, as a novel tissue-engineering concept and living cell-based therapy, proved to be a reliable and successful treatment concept.
PB  - Wiley, Hoboken
T2  - Journal of Periodontal Research
T1  - Clinical application of autologous fibroblast cell culture in gingival recession treatment
VL  - 50
IS  - 3
SP  - 363
EP  - 370
DO  - 10.1111/jre.12215
ER  - 

@article{
author = "Milinković, Iva and Aleksić, Zoran and Janković, Saša and Popović, O. and Bajić, Miljan and Čakić, Saša and Leković, Vojislav",
year = "2015",
abstract = "Background and ObjectiveGingival recession is defined as soft and hard tissue displacement resulting in root surface exposure. The optimal outcome of gingival recession treatment is complete, predictable and long-lasting root coverage with a significant level of tissue regeneration. Tissue engineering, which applies active regeneration principles, presents the contemporary treatment approach in the restitution and regeneration of lost tissues. The objective of the present study was to evaluate and compare the clinical results of application of an autologous fibroblast cell culture (AFCC) on a collagen matrix and a connective tissue graft (CTG) placed under a coronally advanced flap (CAF), in the treatment of single and multiple gingival recessions. Material and MethodsEighteen patients from the Department of Periodontology, School of Dentistry, University of Belgrade, were randomly enrolled in this study. Inclusion criteria were the bilateral presence of Miller Class I or II single or multiple maxillary gingival recessions. A split-mouth design was used in the study. The experimental group was treated with AFCC on a collagen scaffold, which was placed under a CAF. The control group received a combination of CTG and CAF. Clinical parameters such as gingival recession coverage, keratinized tissue width, clinical attachment level and gingival index were recorded at baseline and at 12mo postoperatively. The oral hygiene level was assessed by plaque index evaluation. Postoperative healing was evaluated through the healing index, recorded 1, 2 and 3wk postoperatively. The final esthetic outcome was assessed using the mean root coverage esthetic score (RES). ResultsStatistically significant improvement of all parameters assessed was found compared with baseline. A statistically significant difference between groups was observed only in keratinized tissue width. Greater keratinized tissue width is still obtained with the use of CTG. Regarding the tissue-healing results, no statistically significant difference was achieved. The RES results were similar for both groups. ConclusionsWithin the limitations of the present study, both procedures proved to be efficient in gingival recession treatment. AFCC, as a novel tissue-engineering concept and living cell-based therapy, proved to be a reliable and successful treatment concept.",
publisher = "Wiley, Hoboken",
journal = "Journal of Periodontal Research",
title = "Clinical application of autologous fibroblast cell culture in gingival recession treatment",
volume = "50",
number = "3",
pages = "363-370",
doi = "10.1111/jre.12215"
}

Milinković, I., Aleksić, Z., Janković, S., Popović, O., Bajić, M., Čakić, S.,& Leković, V.. (2015). Clinical application of autologous fibroblast cell culture in gingival recession treatment. in Journal of Periodontal Research
Wiley, Hoboken., 50(3), 363-370.
https://doi.org/10.1111/jre.12215

Milinković I, Aleksić Z, Janković S, Popović O, Bajić M, Čakić S, Leković V. Clinical application of autologous fibroblast cell culture in gingival recession treatment. in Journal of Periodontal Research. 2015;50(3):363-370.
doi:10.1111/jre.12215 .

Milinković, Iva, Aleksić, Zoran, Janković, Saša, Popović, O., Bajić, Miljan, Čakić, Saša, Leković, Vojislav, "Clinical application of autologous fibroblast cell culture in gingival recession treatment" in Journal of Periodontal Research, 50, no. 3 (2015):363-370,
https://doi.org/10.1111/jre.12215 . .

TY  - JOUR
AU  - Bajić, Miljan
AU  - Janković, Saša
AU  - Milinković, Iva
AU  - Čakić, Saša
AU  - Perunović, Neda
AU  - Novaković, Nada
AU  - Puletić, Miljan
AU  - Aleksić, Zoran
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1918
AB  - Introduction Gingival recession is a displacement of gingival margin apically to cement-enamel junction. Objective The aim of this study was to compare the results achieved with two different surgical procedures used in gingival recession treatment. Methods Ten patients with bilateral buccal recession on maxillary canines or premolars were included in the study. Professional teeth cleaning was performed before surgery. Recession on the experimental side was treated with connective tissue graft in combination with coronally advanced, split thickness flap (tunnel technique). Control side recession was treated with connective tissue graft in combination with trapezoidal coronally advanced, full thickness flap. Coin toss was used for side decision. The following parameters were evaluated before surgery and 6 months post-op: Vertical Recession Dimension, Clinical Attachment Level, Apico-coronal width of the keratinized tissue, Healing index (Laundry), RES index, and Patient evaluation of esthetic results. Student's t-test was used for statistical analysis. Results Six months after surgery, mean root coverage was 91.5±14.1% and 90.1±14.6% on the experimental and on the control side, respectively. RES index, Healing index (Laundry) and Patient Subjective evaluation of esthetic results showed significantly better results (p≤0.05). Conclusion Both surgical procedures produce highly successful clinical results based on evaluated parameters, but this tunnel technique provides significantly better esthetic results.
AB  - Uvod Gingivalna recesija, koja nastaje kao posledica morfoloških nepravilnosti u mukogingivalnom kompleksu, loše utiče na nastanak i prognozu parodontopatije i odlikuje se nezadovoljavajućom estetikom. Cilj rada Cilj ove studije bio je da se uporede rezultati dobijeni primenom dveju različitih hirurških tehnika u lečenju gingivalnih recesija. Metode rada U studiju je uključeno 10 pacijenata Klinike za parodontologiju i oralnu medicinu Stomatološkog fakulteta Univerziteta u Beogradu. Osnovni kriterijum za uključivanje u studiju bilo je postojanje obostranih gingivalnih recesija I ili II klase prema klasifikaciji Milera (Miller) na gornjim očnjacima ili premolarima. Izvođenje studije odobrio je Etički odbor Stomatološkog fakulteta. Ispitanici su podvrgnuti hirurškom lečenju, obostrano, primenom metoda podeljenih usta. Jedna strana tretirana je primenom transplantata vezivnog tkiva tunel- tehnikom (eksperimentalna tehnika), a druga konvencionalnom tehnikom (kontrolna tehnika). Posmatrani klinički parametri - vertikalna dimenzija gingivalne recesije, nivo pripojnog epitela i širina keratinizovane gingive - zabeleženi su pre operacije i šest meseci nakon hirurškog lečenja. Zarastanje u ranoj postoperacionoj fazi procenjivano je na osnovu vrednosti indeksa tkivnog zarastanja. Objektivna procena estetskog ishoda terapije vršena je pomoću indeksa prekrivenosti korena zuba. Rezultati Šest meseci nakon intervencije primenom eksperimentalne tehnike ostvarena je prekrivenost korena od 91,5±14,1%, dok je primenom kontrolne tehnike ostvarena pokrivenost korena od 90,1±14,6%. Parametri za objektivnu procenu postignutih estetskih rezultata i indeksa zarastanja rane pokazali su statistički značajno bolje rezultate ostvarene primenom eksperimentalne tehnike. Zaključak Obe procedure uspešne su u lečenju gingivalne recesije i daju predvidljive rezultate, ali se primenom tunel- tehnike mogu očekivati bolji estetski rezultati.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Utilization of two different surgical techniques in gingival recession treatment: A comparative study
T1  - Komparativna analiza primene dveju tehnika transplantata vezivnog tkiva u lečenju recesija gingive
VL  - 142
IS  - 3-4
SP  - 155
EP  - 163
DO  - 10.2298/SARH1404155B
ER  - 

@article{
author = "Bajić, Miljan and Janković, Saša and Milinković, Iva and Čakić, Saša and Perunović, Neda and Novaković, Nada and Puletić, Miljan and Aleksić, Zoran",
year = "2014",
abstract = "Introduction Gingival recession is a displacement of gingival margin apically to cement-enamel junction. Objective The aim of this study was to compare the results achieved with two different surgical procedures used in gingival recession treatment. Methods Ten patients with bilateral buccal recession on maxillary canines or premolars were included in the study. Professional teeth cleaning was performed before surgery. Recession on the experimental side was treated with connective tissue graft in combination with coronally advanced, split thickness flap (tunnel technique). Control side recession was treated with connective tissue graft in combination with trapezoidal coronally advanced, full thickness flap. Coin toss was used for side decision. The following parameters were evaluated before surgery and 6 months post-op: Vertical Recession Dimension, Clinical Attachment Level, Apico-coronal width of the keratinized tissue, Healing index (Laundry), RES index, and Patient evaluation of esthetic results. Student's t-test was used for statistical analysis. Results Six months after surgery, mean root coverage was 91.5±14.1% and 90.1±14.6% on the experimental and on the control side, respectively. RES index, Healing index (Laundry) and Patient Subjective evaluation of esthetic results showed significantly better results (p≤0.05). Conclusion Both surgical procedures produce highly successful clinical results based on evaluated parameters, but this tunnel technique provides significantly better esthetic results., Uvod Gingivalna recesija, koja nastaje kao posledica morfoloških nepravilnosti u mukogingivalnom kompleksu, loše utiče na nastanak i prognozu parodontopatije i odlikuje se nezadovoljavajućom estetikom. Cilj rada Cilj ove studije bio je da se uporede rezultati dobijeni primenom dveju različitih hirurških tehnika u lečenju gingivalnih recesija. Metode rada U studiju je uključeno 10 pacijenata Klinike za parodontologiju i oralnu medicinu Stomatološkog fakulteta Univerziteta u Beogradu. Osnovni kriterijum za uključivanje u studiju bilo je postojanje obostranih gingivalnih recesija I ili II klase prema klasifikaciji Milera (Miller) na gornjim očnjacima ili premolarima. Izvođenje studije odobrio je Etički odbor Stomatološkog fakulteta. Ispitanici su podvrgnuti hirurškom lečenju, obostrano, primenom metoda podeljenih usta. Jedna strana tretirana je primenom transplantata vezivnog tkiva tunel- tehnikom (eksperimentalna tehnika), a druga konvencionalnom tehnikom (kontrolna tehnika). Posmatrani klinički parametri - vertikalna dimenzija gingivalne recesije, nivo pripojnog epitela i širina keratinizovane gingive - zabeleženi su pre operacije i šest meseci nakon hirurškog lečenja. Zarastanje u ranoj postoperacionoj fazi procenjivano je na osnovu vrednosti indeksa tkivnog zarastanja. Objektivna procena estetskog ishoda terapije vršena je pomoću indeksa prekrivenosti korena zuba. Rezultati Šest meseci nakon intervencije primenom eksperimentalne tehnike ostvarena je prekrivenost korena od 91,5±14,1%, dok je primenom kontrolne tehnike ostvarena pokrivenost korena od 90,1±14,6%. Parametri za objektivnu procenu postignutih estetskih rezultata i indeksa zarastanja rane pokazali su statistički značajno bolje rezultate ostvarene primenom eksperimentalne tehnike. Zaključak Obe procedure uspešne su u lečenju gingivalne recesije i daju predvidljive rezultate, ali se primenom tunel- tehnike mogu očekivati bolji estetski rezultati.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Utilization of two different surgical techniques in gingival recession treatment: A comparative study, Komparativna analiza primene dveju tehnika transplantata vezivnog tkiva u lečenju recesija gingive",
volume = "142",
number = "3-4",
pages = "155-163",
doi = "10.2298/SARH1404155B"
}

Bajić, M., Janković, S., Milinković, I., Čakić, S., Perunović, N., Novaković, N., Puletić, M.,& Aleksić, Z.. (2014). Utilization of two different surgical techniques in gingival recession treatment: A comparative study. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 142(3-4), 155-163.
https://doi.org/10.2298/SARH1404155B

Bajić M, Janković S, Milinković I, Čakić S, Perunović N, Novaković N, Puletić M, Aleksić Z. Utilization of two different surgical techniques in gingival recession treatment: A comparative study. in Srpski arhiv za celokupno lekarstvo. 2014;142(3-4):155-163.
doi:10.2298/SARH1404155B .

Bajić, Miljan, Janković, Saša, Milinković, Iva, Čakić, Saša, Perunović, Neda, Novaković, Nada, Puletić, Miljan, Aleksić, Zoran, "Utilization of two different surgical techniques in gingival recession treatment: A comparative study" in Srpski arhiv za celokupno lekarstvo, 142, no. 3-4 (2014):155-163,
https://doi.org/10.2298/SARH1404155B . .

TY  - JOUR
AU  - Novaković, N.
AU  - Todorović, Tatjana
AU  - Rakić, Mia
AU  - Milinković, Iva
AU  - Dožić, Ivan
AU  - Janković, Saša
AU  - Aleksić, Zoran
AU  - Čakić, Saša
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1880
AB  - Background and objective: One of the major pathologic patterns in periodontitis represents an imbalance among the production of free radicals and local antioxidants resulting in periodontal tissue destruction. The objective of the study was to investigate the influence of non-surgical periodontal treatment on salivary antioxidants and to evaluate their capacity as biomarkers reflecting periodontal tissue condition and therapy outcome. Material and Methods: Sixty-three systemically healthy non-smokers, including 21 periodontally healthy subjects (HC) and 42 patients with current chronic periodontitis fulfilled the inclusion criteria. Half of the patients received scaling and root planing (SRP) and the other half received only oral hygiene instructions. Full mouth clinical measurements, including gingival index (GI), plaque index (PI), periodontal pocket depth, clinical attachment level and saliva sampling were performed at baseline visit and 2 mo after treatment/baseline visit. Total antioxidant capacity (TAOC), albumins (ALB), uric acid (UA), superoxide dismutase (SOD) and glutathione peroxidase (GPX) were evaluated in saliva samples using commercial kits. Results: All measured antioxidants were affected by treatment resulting in significant increase in TAOC (p  lt  0.005), ALB (p  lt  0.001), UA (p  lt  0.001) and GPX (p  lt  0.001) and decrease of SOD (p  lt  0.005) in response to SRP, where no differences were observed for any of parameters in the oral hygiene instructions group. Comparison of antioxidant levels between the HC and SRP group showed that before treatment ALB were significantly higher in HC when compared to the SRP group (p = 0.039), and GXP (p = 0.000) and SOD (p = 0.021) levels were significantly higher in the SRP group. Comparison of values after treatment showed that TAOC was significantly higher in the HC than in the SRP group (p = 0.001), but UA was, inversely, significantly higher in the SRP group (p = 0.034). All clinical parameters except clinical attachment level were significantly decreased after SRP and significant correlations were observed between SOD and GI (p = 0.017), SOD and PI (p = 0.011), GPX and GI (p = 0.003) and GPX and PI (p = 0.008). Conclusion: Non-surgical periodontal treatment affected salivary TAOC, ALB, UA, SOD and GPX; moreover, these biochemical parameters convincingly reflected periodontal status and tissue response on treatment.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Periodontal Research
T1  - Salivary antioxidants as periodontal biomarkers in evaluation of tissue status and treatment outcome
VL  - 49
IS  - 1
SP  - 129
EP  - 136
DO  - 10.1111/jre.12088
ER  - 

@article{
author = "Novaković, N. and Todorović, Tatjana and Rakić, Mia and Milinković, Iva and Dožić, Ivan and Janković, Saša and Aleksić, Zoran and Čakić, Saša",
year = "2014",
abstract = "Background and objective: One of the major pathologic patterns in periodontitis represents an imbalance among the production of free radicals and local antioxidants resulting in periodontal tissue destruction. The objective of the study was to investigate the influence of non-surgical periodontal treatment on salivary antioxidants and to evaluate their capacity as biomarkers reflecting periodontal tissue condition and therapy outcome. Material and Methods: Sixty-three systemically healthy non-smokers, including 21 periodontally healthy subjects (HC) and 42 patients with current chronic periodontitis fulfilled the inclusion criteria. Half of the patients received scaling and root planing (SRP) and the other half received only oral hygiene instructions. Full mouth clinical measurements, including gingival index (GI), plaque index (PI), periodontal pocket depth, clinical attachment level and saliva sampling were performed at baseline visit and 2 mo after treatment/baseline visit. Total antioxidant capacity (TAOC), albumins (ALB), uric acid (UA), superoxide dismutase (SOD) and glutathione peroxidase (GPX) were evaluated in saliva samples using commercial kits. Results: All measured antioxidants were affected by treatment resulting in significant increase in TAOC (p  lt  0.005), ALB (p  lt  0.001), UA (p  lt  0.001) and GPX (p  lt  0.001) and decrease of SOD (p  lt  0.005) in response to SRP, where no differences were observed for any of parameters in the oral hygiene instructions group. Comparison of antioxidant levels between the HC and SRP group showed that before treatment ALB were significantly higher in HC when compared to the SRP group (p = 0.039), and GXP (p = 0.000) and SOD (p = 0.021) levels were significantly higher in the SRP group. Comparison of values after treatment showed that TAOC was significantly higher in the HC than in the SRP group (p = 0.001), but UA was, inversely, significantly higher in the SRP group (p = 0.034). All clinical parameters except clinical attachment level were significantly decreased after SRP and significant correlations were observed between SOD and GI (p = 0.017), SOD and PI (p = 0.011), GPX and GI (p = 0.003) and GPX and PI (p = 0.008). Conclusion: Non-surgical periodontal treatment affected salivary TAOC, ALB, UA, SOD and GPX; moreover, these biochemical parameters convincingly reflected periodontal status and tissue response on treatment.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Periodontal Research",
title = "Salivary antioxidants as periodontal biomarkers in evaluation of tissue status and treatment outcome",
volume = "49",
number = "1",
pages = "129-136",
doi = "10.1111/jre.12088"
}

Novaković, N., Todorović, T., Rakić, M., Milinković, I., Dožić, I., Janković, S., Aleksić, Z.,& Čakić, S.. (2014). Salivary antioxidants as periodontal biomarkers in evaluation of tissue status and treatment outcome. in Journal of Periodontal Research
Wiley-Blackwell, Hoboken., 49(1), 129-136.
https://doi.org/10.1111/jre.12088

Novaković N, Todorović T, Rakić M, Milinković I, Dožić I, Janković S, Aleksić Z, Čakić S. Salivary antioxidants as periodontal biomarkers in evaluation of tissue status and treatment outcome. in Journal of Periodontal Research. 2014;49(1):129-136.
doi:10.1111/jre.12088 .

Novaković, N., Todorović, Tatjana, Rakić, Mia, Milinković, Iva, Dožić, Ivan, Janković, Saša, Aleksić, Zoran, Čakić, Saša, "Salivary antioxidants as periodontal biomarkers in evaluation of tissue status and treatment outcome" in Journal of Periodontal Research, 49, no. 1 (2014):129-136,
https://doi.org/10.1111/jre.12088 . .

TY  - JOUR
AU  - Leković, Vojislav
AU  - Milinković, Iva
AU  - Aleksić, Zoran
AU  - Janković, Saša
AU  - Stanković, P.
AU  - Kenney, Barrie
AU  - Camargo, Paulo
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1762
AB  - Lekovic V, Milinkovic I, Aleksic Z, Jankovic S, Stankovic P, Kenney EB, Camargo PM. Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects. J Periodont Res 2012; 47: 409417. (c) 2011 John Wiley & Sons A/S Background and Objective: Bovine porous bone mineral (BPBM) is a xenograft that has been successfully utilized in periodontal regeneration. Platelet-rich fibrin (PRF) is a leukocyte and platelet preparation that concentrates various polypeptide growth factors and therefore has the potential to be used as regenerative treatment for periodontal defects. The purpose of this study was to examine the suitability of autologous PRF as regenerative treatment for periodontal intrabony defects in humans and to examine the ability of BPBM to augment the regenerative effects exerted by PRF. Material and Methods: Using a split-mouth design, 17 paired intrabony defects were randomly treated either with PRF or with PRFBPBM combination. Re-entry surgeries were performed at 6 mo. Primary study outcomes were changes in pocket depth, attachment level and defect fill. Results: Preoperative pocket depths, attachment levels and transoperative bone measurements were similar for the PRF and PRFBPBM groups. Postsurgical measurements revealed a significantly greater reduction in pocket depth in the PRFBPBM group (4.47 +/- 0.78 mm on buccal and 4.29 +/- 0.82 mm on lingual sites) when compared with the PRF group (3.35 +/- 0.68 mm on buccal and 3.24 +/- 0.73 mm on lingual sites). The PRFBPBM group presented with significantly greater attachment gain (3.82 +/- 0.78 mm on buccal and 3.71 +/- 0.75 mm on lingual sites) than the PRF group (2.24 +/- 0.73 mm on buccal and 2.12 +/- 0.68 mm on lingual sites). Defect fill was also greater in the PRFBPBM group (4.06 +/- 0.87 mm on buccal and 3.94 +/- 0.73 mm on lingual sites) than in the PRF group (2.21 +/- 0.68 mm on buccal and 2.06 +/- 0.64 mm on lingual sites). Conclusion: The results of this study indicate that PRF can improve clinical parameters associated with human intrabony periodontal defects, and BPBM has the ability to augment the effects of PRF in reducing pocket depth, improving clinical attachment levels and promoting defect fill.
PB  - Wiley, Hoboken
T2  - Journal of Periodontal Research
T1  - Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects
VL  - 47
IS  - 4
SP  - 409
EP  - 417
DO  - 10.1111/j.1600-0765.2011.01446.x
ER  - 

@article{
author = "Leković, Vojislav and Milinković, Iva and Aleksić, Zoran and Janković, Saša and Stanković, P. and Kenney, Barrie and Camargo, Paulo",
year = "2012",
abstract = "Lekovic V, Milinkovic I, Aleksic Z, Jankovic S, Stankovic P, Kenney EB, Camargo PM. Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects. J Periodont Res 2012; 47: 409417. (c) 2011 John Wiley & Sons A/S Background and Objective: Bovine porous bone mineral (BPBM) is a xenograft that has been successfully utilized in periodontal regeneration. Platelet-rich fibrin (PRF) is a leukocyte and platelet preparation that concentrates various polypeptide growth factors and therefore has the potential to be used as regenerative treatment for periodontal defects. The purpose of this study was to examine the suitability of autologous PRF as regenerative treatment for periodontal intrabony defects in humans and to examine the ability of BPBM to augment the regenerative effects exerted by PRF. Material and Methods: Using a split-mouth design, 17 paired intrabony defects were randomly treated either with PRF or with PRFBPBM combination. Re-entry surgeries were performed at 6 mo. Primary study outcomes were changes in pocket depth, attachment level and defect fill. Results: Preoperative pocket depths, attachment levels and transoperative bone measurements were similar for the PRF and PRFBPBM groups. Postsurgical measurements revealed a significantly greater reduction in pocket depth in the PRFBPBM group (4.47 +/- 0.78 mm on buccal and 4.29 +/- 0.82 mm on lingual sites) when compared with the PRF group (3.35 +/- 0.68 mm on buccal and 3.24 +/- 0.73 mm on lingual sites). The PRFBPBM group presented with significantly greater attachment gain (3.82 +/- 0.78 mm on buccal and 3.71 +/- 0.75 mm on lingual sites) than the PRF group (2.24 +/- 0.73 mm on buccal and 2.12 +/- 0.68 mm on lingual sites). Defect fill was also greater in the PRFBPBM group (4.06 +/- 0.87 mm on buccal and 3.94 +/- 0.73 mm on lingual sites) than in the PRF group (2.21 +/- 0.68 mm on buccal and 2.06 +/- 0.64 mm on lingual sites). Conclusion: The results of this study indicate that PRF can improve clinical parameters associated with human intrabony periodontal defects, and BPBM has the ability to augment the effects of PRF in reducing pocket depth, improving clinical attachment levels and promoting defect fill.",
publisher = "Wiley, Hoboken",
journal = "Journal of Periodontal Research",
title = "Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects",
volume = "47",
number = "4",
pages = "409-417",
doi = "10.1111/j.1600-0765.2011.01446.x"
}

Leković, V., Milinković, I., Aleksić, Z., Janković, S., Stanković, P., Kenney, B.,& Camargo, P.. (2012). Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects. in Journal of Periodontal Research
Wiley, Hoboken., 47(4), 409-417.
https://doi.org/10.1111/j.1600-0765.2011.01446.x

Leković V, Milinković I, Aleksić Z, Janković S, Stanković P, Kenney B, Camargo P. Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects. in Journal of Periodontal Research. 2012;47(4):409-417.
doi:10.1111/j.1600-0765.2011.01446.x .

Leković, Vojislav, Milinković, Iva, Aleksić, Zoran, Janković, Saša, Stanković, P., Kenney, Barrie, Camargo, Paulo, "Platelet-rich fibrin and bovine porous bone mineral vs. platelet-rich fibrin in the treatment of intrabony periodontal defects" in Journal of Periodontal Research, 47, no. 4 (2012):409-417,
https://doi.org/10.1111/j.1600-0765.2011.01446.x . .

TY  - JOUR
AU  - Špadijer-Gostović, Aleksandra
AU  - Todorović, Aleksandar
AU  - Lazić, Vojkan
AU  - Todorović, Ana
AU  - Milinković, Iva
AU  - Leković, Vojislav
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1716
AB  - Background/Aim. Immediate loading is considered to be the most innovative technique in contemporary implant dentistry. Recent clinical and experimental findings have demonstrated that only implants with high primary stability can be subjected to immediate loading protocol with predictable results. It is generally accepted that the most important prerequsite for successful osseointegration is achievement and maintenance of implant stability. The aim of this in vivo study was to investigate the possibility for successful application of immediate loading protocol in implant systems with different surface properties. Methods. In the experimental study 2 mongrel dogs were edentulated bilaterally in the mandibular and maxillary premolar areas. After 3 months implants were placed in a pattern 4 different commercially available implants per quadrant (n = 32): Mk III TiUnite (Nobel Biocare, Sweden), ITI TPS (Straumann, Switzerland), 3IOsseotite (Implant Innovation, USA) and XiVE Cell-Plus (Friadent, Germany). Implants were subjected to immediate loading with 4 unit gold cast bridges, 2 days post implantation. The assessment of implant stability and immediate loading possibilities were done by performing Resonance frequency analysis (RFA). Results. After a 6- month loading period all bridges were in function and all implants occurred well osseointegrated. When summarizing the Implant Stability Quotient (ISQ) values, it was noted that resonance frequency was significantly higher for mandibular implants. The results of this experimental setting showed that all evaluated surfaces achieved good implant stability. Increase of ISQ values was found for all implants in the mandible and partially decrease of ISQ values for maxillary implants after 6 months of functional loading with 4 unit bridges. Conclusions. Investigated endooseal implants did not show different degree of osseointegration, because there was not statistically significant difference among observed parameters (ISQh i ISQp) between implant systems.
AB  - Uvod/Cilj. Imedijatno opterećenje implantata smatra se jednim od najznačajnijih dostignuća savremene dentalne implantologije. Rezultati novijih kliničkih i eksperimentalnih studija pokazali su da samo implantati visoke primarne stabilnosti mogu biti izloženi protokolu imedijatnog opterećenja zubnom nadoknadom sa predvidivim ishodom. Cilj studije bio je da se ispita mogućnost uspešne primene protokola imedijatnog opterećenja implantata različitog mikrodizajna fiksnim zubnim nadoknadama. Metode. U eksperimentalno istraživanje uključena su dva psa, obezubljena obostrano u premolarnoj regiji gornje i donje vilice. Nakon tri meseca od ekstrakcije zuba, ugrađena su, po predviđenoj šemi, četiri različita implantata po kvadrantu (n = 32): Mk III TiUnite (Nobel Biocare, Sweden), ITI TPS (Straumann, Switzerland), 3I-Osseotite (Implant Innovation, USA) i XiVE Cell-Plus (Friadent, Germany). Implantati su imedijatno opterećeni fiksnim zubnim nadoknadama, četvoročlanim mostovima od plemenite legure zlato-platina, dva dana posle implantacije. Stabilnost implantata i mogućnost imedijatnog opterećenja ocenjivana je na osnovu analize rezonantnih frekvencija (RFA). Rezultati. Šest meseci nakon implantacije i imedijatnog opterećenja fiksnom zubnom nadoknadom, svi mostovi bili su u funkciji i svi implantati uspešno integrisani, ne pokazujući znake mobilnosti. Sumiranjem dobijenih vrednosti koeficijenta stabilnosti implantata (ISQ) ustanovljeno je da su rezonantne frekvencije bile značajno veće kod implantata u donjoj vilici. Rezultati eksperimentalnog istraživanja pokazali su da su sve analizirane površine ostvarile dobru implantatnu stabilnost. Utvrđen je porast ISQ vrednosti kod svih implantata u mandibuli i delimičan pad ISQ vrednosti za implantate u maksili, nakon šest meseci funkcionalnog opterećenja fiksnim zubnim nadoknadama. Zaključak. Ispitivani endoosealni implantati nisu pokazali različit stepen oseointegracije jer se rezultati merenih parametara hirurških (ISQh) i protetkih (ISQp), nisu statistički značajno razlikovali između implantatnih sistema.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Immediate implant loading with fixed dental restorations: An animal model study
T1  - Imedijatno opterećenje implantata fiksnim zubnim nadoknadama - studija na psima
VL  - 69
IS  - 2
SP  - 181
EP  - 189
DO  - 10.2298/VSP1202181S
ER  - 

@article{
author = "Špadijer-Gostović, Aleksandra and Todorović, Aleksandar and Lazić, Vojkan and Todorović, Ana and Milinković, Iva and Leković, Vojislav",
year = "2012",
abstract = "Background/Aim. Immediate loading is considered to be the most innovative technique in contemporary implant dentistry. Recent clinical and experimental findings have demonstrated that only implants with high primary stability can be subjected to immediate loading protocol with predictable results. It is generally accepted that the most important prerequsite for successful osseointegration is achievement and maintenance of implant stability. The aim of this in vivo study was to investigate the possibility for successful application of immediate loading protocol in implant systems with different surface properties. Methods. In the experimental study 2 mongrel dogs were edentulated bilaterally in the mandibular and maxillary premolar areas. After 3 months implants were placed in a pattern 4 different commercially available implants per quadrant (n = 32): Mk III TiUnite (Nobel Biocare, Sweden), ITI TPS (Straumann, Switzerland), 3IOsseotite (Implant Innovation, USA) and XiVE Cell-Plus (Friadent, Germany). Implants were subjected to immediate loading with 4 unit gold cast bridges, 2 days post implantation. The assessment of implant stability and immediate loading possibilities were done by performing Resonance frequency analysis (RFA). Results. After a 6- month loading period all bridges were in function and all implants occurred well osseointegrated. When summarizing the Implant Stability Quotient (ISQ) values, it was noted that resonance frequency was significantly higher for mandibular implants. The results of this experimental setting showed that all evaluated surfaces achieved good implant stability. Increase of ISQ values was found for all implants in the mandible and partially decrease of ISQ values for maxillary implants after 6 months of functional loading with 4 unit bridges. Conclusions. Investigated endooseal implants did not show different degree of osseointegration, because there was not statistically significant difference among observed parameters (ISQh i ISQp) between implant systems., Uvod/Cilj. Imedijatno opterećenje implantata smatra se jednim od najznačajnijih dostignuća savremene dentalne implantologije. Rezultati novijih kliničkih i eksperimentalnih studija pokazali su da samo implantati visoke primarne stabilnosti mogu biti izloženi protokolu imedijatnog opterećenja zubnom nadoknadom sa predvidivim ishodom. Cilj studije bio je da se ispita mogućnost uspešne primene protokola imedijatnog opterećenja implantata različitog mikrodizajna fiksnim zubnim nadoknadama. Metode. U eksperimentalno istraživanje uključena su dva psa, obezubljena obostrano u premolarnoj regiji gornje i donje vilice. Nakon tri meseca od ekstrakcije zuba, ugrađena su, po predviđenoj šemi, četiri različita implantata po kvadrantu (n = 32): Mk III TiUnite (Nobel Biocare, Sweden), ITI TPS (Straumann, Switzerland), 3I-Osseotite (Implant Innovation, USA) i XiVE Cell-Plus (Friadent, Germany). Implantati su imedijatno opterećeni fiksnim zubnim nadoknadama, četvoročlanim mostovima od plemenite legure zlato-platina, dva dana posle implantacije. Stabilnost implantata i mogućnost imedijatnog opterećenja ocenjivana je na osnovu analize rezonantnih frekvencija (RFA). Rezultati. Šest meseci nakon implantacije i imedijatnog opterećenja fiksnom zubnom nadoknadom, svi mostovi bili su u funkciji i svi implantati uspešno integrisani, ne pokazujući znake mobilnosti. Sumiranjem dobijenih vrednosti koeficijenta stabilnosti implantata (ISQ) ustanovljeno je da su rezonantne frekvencije bile značajno veće kod implantata u donjoj vilici. Rezultati eksperimentalnog istraživanja pokazali su da su sve analizirane površine ostvarile dobru implantatnu stabilnost. Utvrđen je porast ISQ vrednosti kod svih implantata u mandibuli i delimičan pad ISQ vrednosti za implantate u maksili, nakon šest meseci funkcionalnog opterećenja fiksnim zubnim nadoknadama. Zaključak. Ispitivani endoosealni implantati nisu pokazali različit stepen oseointegracije jer se rezultati merenih parametara hirurških (ISQh) i protetkih (ISQp), nisu statistički značajno razlikovali između implantatnih sistema.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Immediate implant loading with fixed dental restorations: An animal model study, Imedijatno opterećenje implantata fiksnim zubnim nadoknadama - studija na psima",
volume = "69",
number = "2",
pages = "181-189",
doi = "10.2298/VSP1202181S"
}

Špadijer-Gostović, A., Todorović, A., Lazić, V., Todorović, A., Milinković, I.,& Leković, V.. (2012). Immediate implant loading with fixed dental restorations: An animal model study. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 69(2), 181-189.
https://doi.org/10.2298/VSP1202181S

Špadijer-Gostović A, Todorović A, Lazić V, Todorović A, Milinković I, Leković V. Immediate implant loading with fixed dental restorations: An animal model study. in Vojnosanitetski pregled. 2012;69(2):181-189.
doi:10.2298/VSP1202181S .

Špadijer-Gostović, Aleksandra, Todorović, Aleksandar, Lazić, Vojkan, Todorović, Ana, Milinković, Iva, Leković, Vojislav, "Immediate implant loading with fixed dental restorations: An animal model study" in Vojnosanitetski pregled, 69, no. 2 (2012):181-189,
https://doi.org/10.2298/VSP1202181S . .

TY  - JOUR
AU  - Milinković, Iva
AU  - Rudolf, Rebeka
AU  - Raić, Karlo T.
AU  - Aleksić, Zoran
AU  - Lazić, Vojkan
AU  - Todorović, Aleksandar
AU  - Stamenković, Dragoslav
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1680
AB  - The shape and chemical composition, as well as the macro- and microtopography, of an implant surface have been studied widely as the major factors that positively influence implant osseointegration. Titanium and titanium alloys have been used extensively over the past 20 years as biomedical materials in orthopedic and dental surgery because of their good mechanical properties, corrosion resistance, no cell toxicity, and very poor inflammatory response in pen-implant tissue, which confirms their high biocompatibility. Their favorable biological performance is attributed to a thin native oxide film that forms spontaneously on the titanium surface. It is well established that surface roughness plays an important role in implant fixation. Accordingly, some authors have indicated the existence of an optimal range of surface roughness. The titanium surface can be either chemically or physically modified, or both, in order to improve biomaterial tissue integration. Different treatments are used to modify the titanium surface. Hydroxyapatite coatings, preceded or not by acid etching, are used to create a rough, potentially bioactive surface. Oxide blasting treatments, either with or without chemical etching, are used to develop rough surfaces. Thick oxide films obtained by anodic or thermal oxidation have been used to accelerate the osseointegration process. The ideal microtopography of the surface is still unknown, however, because it is very difficult to associate surface properties with clinical results. As more accurate knowledge is required, several Ti surfaces have been analyzed and the endosseous implant surface modified on the micro level has been thoroughly studied. Additionally, the production of gold (Au) nanoparticles to be added to the micron-scale modified surface has been performed. In this respect, an appropriate overview of our results is given.
PB  - Institute of Metals and Technology
T2  - Materiali in Tehnologije
T1  - Aspects of titanium-implant surface modification at the micro and nano levels
VL  - 46
IS  - 3
SP  - 251
EP  - 256
UR  - https://hdl.handle.net/21.15107/rcub_smile_1680
ER  - 

@article{
author = "Milinković, Iva and Rudolf, Rebeka and Raić, Karlo T. and Aleksić, Zoran and Lazić, Vojkan and Todorović, Aleksandar and Stamenković, Dragoslav",
year = "2012",
abstract = "The shape and chemical composition, as well as the macro- and microtopography, of an implant surface have been studied widely as the major factors that positively influence implant osseointegration. Titanium and titanium alloys have been used extensively over the past 20 years as biomedical materials in orthopedic and dental surgery because of their good mechanical properties, corrosion resistance, no cell toxicity, and very poor inflammatory response in pen-implant tissue, which confirms their high biocompatibility. Their favorable biological performance is attributed to a thin native oxide film that forms spontaneously on the titanium surface. It is well established that surface roughness plays an important role in implant fixation. Accordingly, some authors have indicated the existence of an optimal range of surface roughness. The titanium surface can be either chemically or physically modified, or both, in order to improve biomaterial tissue integration. Different treatments are used to modify the titanium surface. Hydroxyapatite coatings, preceded or not by acid etching, are used to create a rough, potentially bioactive surface. Oxide blasting treatments, either with or without chemical etching, are used to develop rough surfaces. Thick oxide films obtained by anodic or thermal oxidation have been used to accelerate the osseointegration process. The ideal microtopography of the surface is still unknown, however, because it is very difficult to associate surface properties with clinical results. As more accurate knowledge is required, several Ti surfaces have been analyzed and the endosseous implant surface modified on the micro level has been thoroughly studied. Additionally, the production of gold (Au) nanoparticles to be added to the micron-scale modified surface has been performed. In this respect, an appropriate overview of our results is given.",
publisher = "Institute of Metals and Technology",
journal = "Materiali in Tehnologije",
title = "Aspects of titanium-implant surface modification at the micro and nano levels",
volume = "46",
number = "3",
pages = "251-256",
url = "https://hdl.handle.net/21.15107/rcub_smile_1680"
}

Milinković, I., Rudolf, R., Raić, K. T., Aleksić, Z., Lazić, V., Todorović, A.,& Stamenković, D.. (2012). Aspects of titanium-implant surface modification at the micro and nano levels. in Materiali in Tehnologije
Institute of Metals and Technology., 46(3), 251-256.
https://hdl.handle.net/21.15107/rcub_smile_1680

Milinković I, Rudolf R, Raić KT, Aleksić Z, Lazić V, Todorović A, Stamenković D. Aspects of titanium-implant surface modification at the micro and nano levels. in Materiali in Tehnologije. 2012;46(3):251-256.
https://hdl.handle.net/21.15107/rcub_smile_1680 .

Milinković, Iva, Rudolf, Rebeka, Raić, Karlo T., Aleksić, Zoran, Lazić, Vojkan, Todorović, Aleksandar, Stamenković, Dragoslav, "Aspects of titanium-implant surface modification at the micro and nano levels" in Materiali in Tehnologije, 46, no. 3 (2012):251-256,
https://hdl.handle.net/21.15107/rcub_smile_1680 .

TY  - THES
AU  - Milinković, Iva
PY  - 2011
UR  - https://plus.sr.cobiss.net/opac7/bib/1024181902
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/512
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Klinička evaluacija primene autogene ćelijske kulture fibroblasta u terapiji gingivalnih recesija
UR  - https://hdl.handle.net/21.15107/rcub_smile_512
ER  - 

@phdthesis{
author = "Milinković, Iva",
year = "2011",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Klinička evaluacija primene autogene ćelijske kulture fibroblasta u terapiji gingivalnih recesija",
url = "https://hdl.handle.net/21.15107/rcub_smile_512"
}

Milinković, I.. (2011). Klinička evaluacija primene autogene ćelijske kulture fibroblasta u terapiji gingivalnih recesija. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_512

Milinković I. Klinička evaluacija primene autogene ćelijske kulture fibroblasta u terapiji gingivalnih recesija. 2011;.
https://hdl.handle.net/21.15107/rcub_smile_512 .

Milinković, Iva, "Klinička evaluacija primene autogene ćelijske kulture fibroblasta u terapiji gingivalnih recesija" (2011),
https://hdl.handle.net/21.15107/rcub_smile_512 .

TY  - JOUR
AU  - Janković, Saša
AU  - Aleksić, Zoran
AU  - Dimitrijević, B.
AU  - Leković, Vojislav
AU  - Milinković, Iva
AU  - Kenney, Barrie
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1615
AB  - Background: The purpose of this study was to estimate the prevalence of different genotypes of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites, and to evaluate the correlation between herpesvirus presence and clinical parameters. Methods: A total of 80 dental implants ( mean time of loading, 4.16 +/- 1.8 years) were evaluated during the course of the study (30 peri-implantitis, 25 mucositis and 25 healthy peri-implant sites). The following clinical parameters were assessed: visible plaque index, bleeding on probing, suppuration and probing depth. A polymerase chain reaction (PCR) assay was used to identify the presence of different HCMV and EBV genotypes in peri-implant tissue plaque samples. Results: HCMV-2 was detected in 53.3% and EBV-1 in 46.6% of the 30 peri-implantitis sites evaluated. By contrast, HCMV-2 was not detected in healthy periodontal sites and EBV-1 was detected in one healthy site. A statistically significant correlation was found between the presence of HCMV-2 and EBV-1 genotypes and clinical parameters of peri-implantitis. Conclusions: The results from the present study confirmed the high prevalence of HCMV-2 and EBV-1 in the peri-implant tissue plaque of peri-implantitis sites and suggests a possible active pathogenic role of the viruses in peri-implantitis.
PB  - Wiley, Hoboken
T2  - Australian Dental Journal
T1  - Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status
VL  - 56
IS  - 4
SP  - 382
EP  - 388
DO  - 10.1111/j.1834-7819.2011.01360.x
ER  - 

@article{
author = "Janković, Saša and Aleksić, Zoran and Dimitrijević, B. and Leković, Vojislav and Milinković, Iva and Kenney, Barrie",
year = "2011",
abstract = "Background: The purpose of this study was to estimate the prevalence of different genotypes of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) in peri-implantitis and mucositis sites, and to evaluate the correlation between herpesvirus presence and clinical parameters. Methods: A total of 80 dental implants ( mean time of loading, 4.16 +/- 1.8 years) were evaluated during the course of the study (30 peri-implantitis, 25 mucositis and 25 healthy peri-implant sites). The following clinical parameters were assessed: visible plaque index, bleeding on probing, suppuration and probing depth. A polymerase chain reaction (PCR) assay was used to identify the presence of different HCMV and EBV genotypes in peri-implant tissue plaque samples. Results: HCMV-2 was detected in 53.3% and EBV-1 in 46.6% of the 30 peri-implantitis sites evaluated. By contrast, HCMV-2 was not detected in healthy periodontal sites and EBV-1 was detected in one healthy site. A statistically significant correlation was found between the presence of HCMV-2 and EBV-1 genotypes and clinical parameters of peri-implantitis. Conclusions: The results from the present study confirmed the high prevalence of HCMV-2 and EBV-1 in the peri-implant tissue plaque of peri-implantitis sites and suggests a possible active pathogenic role of the viruses in peri-implantitis.",
publisher = "Wiley, Hoboken",
journal = "Australian Dental Journal",
title = "Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status",
volume = "56",
number = "4",
pages = "382-388",
doi = "10.1111/j.1834-7819.2011.01360.x"
}

Janković, S., Aleksić, Z., Dimitrijević, B., Leković, V., Milinković, I.,& Kenney, B.. (2011). Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status. in Australian Dental Journal
Wiley, Hoboken., 56(4), 382-388.
https://doi.org/10.1111/j.1834-7819.2011.01360.x

Janković S, Aleksić Z, Dimitrijević B, Leković V, Milinković I, Kenney B. Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status. in Australian Dental Journal. 2011;56(4):382-388.
doi:10.1111/j.1834-7819.2011.01360.x .

Janković, Saša, Aleksić, Zoran, Dimitrijević, B., Leković, Vojislav, Milinković, Iva, Kenney, Barrie, "Correlation between different genotypes of human cytomegalovirus and Epstein-Barr virus and peri-implant tissue status" in Australian Dental Journal, 56, no. 4 (2011):382-388,
https://doi.org/10.1111/j.1834-7819.2011.01360.x . .

TY  - JOUR
AU  - Janković, Saša
AU  - Aleksić, Zoran
AU  - Milinković, Iva
AU  - Dimitrijević, B.
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1595
AB  - The main objective of this study was to evaluate the clinical effectiveness of platelet-rich fibrin membrane used in combination with a coronally advanced flap (CAF) and to compare it with the use of an enamel matrix derivative (EMD) in combination with a coronally advanced flap in gingival recession treatment. 20 split-mouth cases of maxillary anterior teeth or bicuspids presenting with Miller Class I or II gingival recession were treated with a CAF combined with a platelet-rich fibrin membrane (PRF group) or with EMD (EMD group) placed under a CAF. The following parameters were measured at baseline and at 12 months post treatment: gingival recession (GR), apicocoronal width of the keratinized tissue (WKT), and probing depth (PD). Complete rot coverage in the PRF group was 65% (13 out of 20 recessions) and 60% in the EMD group (12 out of 20 recessions). GR was 4.10 ± 1.05 mm in the PRF group and 3.90 ± 1.00 mm in the EMD group at baseline, and 1.05 ± 0.45 mm in the PRF group and 1.15 ± 0.65 mm in the EMD group at 12 months. The difference observed between the tow groups at 12 months was statistically significant. Average root coverage was 70.5% in the EMD group and 72.1% in the PRF group. WKT was 1.30 ± 0.56 mm in the EMD group and 1.45 ± 0.86 mm in the PRF group at baseline, and 1.90 ± 0.81 mm in the EMD group and 1.62 ± 0.28 mm in the PRF group at 12 months. The difference observed between the two groups at 12 months was not statistically significant. Twelve-month changes in PD were not significantly different between the two groups. The pain intensity was statistically different between the two groups. The pain intensity was statistically different between groups for the first 5 days, favoring the PRF group. The present study did not succeed in demonstrating any clinical advantage of the use of PRF compared to EMD in the coverage of gingival recession with the CAF procedure. The EMD group showed a higher success rate in increasing WKT than did the PRF group.
T2  - The European Journal of Esthetic Dentistry
T1  - The coronally advanced flap in combination with platelet-rich fibrin (PRF) and enamel matrix derivative in the treatment of gingival recession: a comparative study.
VL  - 5
IS  - 3
SP  - 260
EP  - 273
UR  - https://hdl.handle.net/21.15107/rcub_smile_1595
ER  - 

@article{
author = "Janković, Saša and Aleksić, Zoran and Milinković, Iva and Dimitrijević, B.",
year = "2010",
abstract = "The main objective of this study was to evaluate the clinical effectiveness of platelet-rich fibrin membrane used in combination with a coronally advanced flap (CAF) and to compare it with the use of an enamel matrix derivative (EMD) in combination with a coronally advanced flap in gingival recession treatment. 20 split-mouth cases of maxillary anterior teeth or bicuspids presenting with Miller Class I or II gingival recession were treated with a CAF combined with a platelet-rich fibrin membrane (PRF group) or with EMD (EMD group) placed under a CAF. The following parameters were measured at baseline and at 12 months post treatment: gingival recession (GR), apicocoronal width of the keratinized tissue (WKT), and probing depth (PD). Complete rot coverage in the PRF group was 65% (13 out of 20 recessions) and 60% in the EMD group (12 out of 20 recessions). GR was 4.10 ± 1.05 mm in the PRF group and 3.90 ± 1.00 mm in the EMD group at baseline, and 1.05 ± 0.45 mm in the PRF group and 1.15 ± 0.65 mm in the EMD group at 12 months. The difference observed between the tow groups at 12 months was statistically significant. Average root coverage was 70.5% in the EMD group and 72.1% in the PRF group. WKT was 1.30 ± 0.56 mm in the EMD group and 1.45 ± 0.86 mm in the PRF group at baseline, and 1.90 ± 0.81 mm in the EMD group and 1.62 ± 0.28 mm in the PRF group at 12 months. The difference observed between the two groups at 12 months was not statistically significant. Twelve-month changes in PD were not significantly different between the two groups. The pain intensity was statistically different between the two groups. The pain intensity was statistically different between groups for the first 5 days, favoring the PRF group. The present study did not succeed in demonstrating any clinical advantage of the use of PRF compared to EMD in the coverage of gingival recession with the CAF procedure. The EMD group showed a higher success rate in increasing WKT than did the PRF group.",
journal = "The European Journal of Esthetic Dentistry",
title = "The coronally advanced flap in combination with platelet-rich fibrin (PRF) and enamel matrix derivative in the treatment of gingival recession: a comparative study.",
volume = "5",
number = "3",
pages = "260-273",
url = "https://hdl.handle.net/21.15107/rcub_smile_1595"
}

Janković, S., Aleksić, Z., Milinković, I.,& Dimitrijević, B.. (2010). The coronally advanced flap in combination with platelet-rich fibrin (PRF) and enamel matrix derivative in the treatment of gingival recession: a comparative study.. in The European Journal of Esthetic Dentistry, 5(3), 260-273.
https://hdl.handle.net/21.15107/rcub_smile_1595

Janković S, Aleksić Z, Milinković I, Dimitrijević B. The coronally advanced flap in combination with platelet-rich fibrin (PRF) and enamel matrix derivative in the treatment of gingival recession: a comparative study.. in The European Journal of Esthetic Dentistry. 2010;5(3):260-273.
https://hdl.handle.net/21.15107/rcub_smile_1595 .

Janković, Saša, Aleksić, Zoran, Milinković, Iva, Dimitrijević, B., "The coronally advanced flap in combination with platelet-rich fibrin (PRF) and enamel matrix derivative in the treatment of gingival recession: a comparative study." in The European Journal of Esthetic Dentistry, 5, no. 3 (2010):260-273,
https://hdl.handle.net/21.15107/rcub_smile_1595 .

TY  - JOUR
AU  - Aleksić, Zoran
AU  - Janković, Saša
AU  - Dimitrijević, Božidar
AU  - Divnić-Resnik, Tihana
AU  - Milinković, Iva
AU  - Leković, Vojislav
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1558
AB  - Introduction. Fibrin, fibronectin, platelet derived growth factor, and transforming growth factors from platelet concetrate are crucial for tissue reparation and regeneration. Objective. This study was designed to evaluate clinical effectiveness of activated platelet-rich fibrin (PRF) membrane in treatment of gingival recession. Methods. 19 gingival recessions Miller class I or II were treated with a coronally advanced flap and the PRF membrane (PRF group). Following the elevation of the flap, bone and root surfaces were covered with the PRF membrane. After suturing, the PRF membrane was covered with a coronally advanced flap. In the same patients, 19 other gingival recessions were treated with CTG in combination with the coronally advanced flap (the CTG group). Clinical recordings were made of vertical recession depth (VRD), probing depth (PD), clinical attachment level (CAL) and keratinized tissue width (KTW) before and 12 months after mucogingival surgical treatment. Clinical evaluation of healing events was estimated with recordings of the healing index (HI). Recordings of HI were performed in the 1st, 2nd and 3rd week post-surgically. Results. Mean root coverage was significant in both groups (the PRF group 79.94% and the CTG group 88.56% %; p lt 0.01). The difference between the two tested groups was not statistically significant. Results of the keratinized tissue width showed significant increase (p lt 0.05) 12 months after the surgery in both, the PRF and CTG groups. Results of KTW showed statistical significance of recorded differences obtained in the two evaluated groups (p lt 0.05). There was no statistical significance in reduction of PD and CAL recorded in the PRF and CTG groups. The values of HI recorded in the 1st and 2nd week postoperatively were significantly enhanced in the PRF group (p lt 0.05). Conclusion. Results of this study confirm both procedures as effective with equivalence of clinical results in solving gingival recession problems. The utilization of the PRF resulted in a decreased postoperative discomfort and advanced tissue healing.
AB  - Uvod. Fibrin, fibronektin, faktor rasta poreklom iz trombocita i transformišući faktor rasta imaju presudnu ulogu u regeneraciji i reparaciji tkiva. Cilj rada. Ispitati i utvrditi značaj primene membrane od fibrina bogatog trombocitima (engl. plateletrich fibrin - PRF) u lečenju recesija gingive. Metode rada. Devetnaest obostranih gingivalnih recesija klase I ili II po Mileru lečeno je sa dva različita terapijska modaliteta. U eksperimentalnoj grupi recesija je, nakon odizanja mukoperiostnog režnja, preko izložene alveolarne kosti i korena zuba postavljena PRF membrana kao augmentacioni materijal, koja je zatim pokrivena koronarno pomerenim režnjem. U kontrolnoj grupi su izložena alveolarna kost i koren zuba prekriveni transplantatom vezivnog tkiva (TVT) uz koronarno pomereni režanj. Kod obe grupe recesija posmatrani su sledeći parametri: veličina recesije gingive, širina keratinizovane gingive, nivo pripojnog epitela i dubina sondiranja. Parametri su mereni neposredno pre hirurškog zahvata i 12 meseci kasnije. Zabeležen je i indeks zarastanja rane tokom prve tri nedelje posle operacije. Rezultati. Kod obe grupe recesija postignuto je značajno prekrivanje ogoljenog korena zuba (PRF membrana 79,94% i TVT 88,56%; p lt 0,01), dok između dve ispitivane grupe nije uočena statistički značajna razlika. Rezultati ispitivanja širine keratinizovane gingive su pokazali značajno povećanje u obe ispitivane grupe dvanaest meseci nakon hirurškog lečenja (p lt 0,05). Takođe je uočena statistički značajna razlika između posmatranih grupa (p lt 0,05) kod parametra širina keratinizovane gingive. Statističke značajnosti kada je reč o smanjenju nivoa pripojnog epitela i dubine sondiranja, kako u okviru grupa, tako i između obe ispitivane grupe (p>0,05), nije bilo. Merenjem indeksa zarastanja rane uočeni su značajno bolji rezultati u eksperimentalnoj grupi nakon prve i druge nedelje nego u kontrolnoj (p lt 0,05). Zaključak. Oba postupka pokazala su se adekvatnim u lečenju gingivalnih recesija. U kontrolnoj grupi bili su bolji rezultati u dobitku keratinizovanog tkiva, dok se eksperimentalna procedura pokazala jednostavnijom i komfornijom za samog bolesnika, uz značajno bolji postoperacioni tok.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - The use of platelet-rich fibrin membrane in gingival recession treatment
T1  - Klinička primena fibrinske membrane u lečenju recesija gingive
VL  - 138
IS  - 1-2
SP  - 11
EP  - 18
DO  - 10.2298/SARH1002011A
ER  - 

@article{
author = "Aleksić, Zoran and Janković, Saša and Dimitrijević, Božidar and Divnić-Resnik, Tihana and Milinković, Iva and Leković, Vojislav",
year = "2010",
abstract = "Introduction. Fibrin, fibronectin, platelet derived growth factor, and transforming growth factors from platelet concetrate are crucial for tissue reparation and regeneration. Objective. This study was designed to evaluate clinical effectiveness of activated platelet-rich fibrin (PRF) membrane in treatment of gingival recession. Methods. 19 gingival recessions Miller class I or II were treated with a coronally advanced flap and the PRF membrane (PRF group). Following the elevation of the flap, bone and root surfaces were covered with the PRF membrane. After suturing, the PRF membrane was covered with a coronally advanced flap. In the same patients, 19 other gingival recessions were treated with CTG in combination with the coronally advanced flap (the CTG group). Clinical recordings were made of vertical recession depth (VRD), probing depth (PD), clinical attachment level (CAL) and keratinized tissue width (KTW) before and 12 months after mucogingival surgical treatment. Clinical evaluation of healing events was estimated with recordings of the healing index (HI). Recordings of HI were performed in the 1st, 2nd and 3rd week post-surgically. Results. Mean root coverage was significant in both groups (the PRF group 79.94% and the CTG group 88.56% %; p lt 0.01). The difference between the two tested groups was not statistically significant. Results of the keratinized tissue width showed significant increase (p lt 0.05) 12 months after the surgery in both, the PRF and CTG groups. Results of KTW showed statistical significance of recorded differences obtained in the two evaluated groups (p lt 0.05). There was no statistical significance in reduction of PD and CAL recorded in the PRF and CTG groups. The values of HI recorded in the 1st and 2nd week postoperatively were significantly enhanced in the PRF group (p lt 0.05). Conclusion. Results of this study confirm both procedures as effective with equivalence of clinical results in solving gingival recession problems. The utilization of the PRF resulted in a decreased postoperative discomfort and advanced tissue healing., Uvod. Fibrin, fibronektin, faktor rasta poreklom iz trombocita i transformišući faktor rasta imaju presudnu ulogu u regeneraciji i reparaciji tkiva. Cilj rada. Ispitati i utvrditi značaj primene membrane od fibrina bogatog trombocitima (engl. plateletrich fibrin - PRF) u lečenju recesija gingive. Metode rada. Devetnaest obostranih gingivalnih recesija klase I ili II po Mileru lečeno je sa dva različita terapijska modaliteta. U eksperimentalnoj grupi recesija je, nakon odizanja mukoperiostnog režnja, preko izložene alveolarne kosti i korena zuba postavljena PRF membrana kao augmentacioni materijal, koja je zatim pokrivena koronarno pomerenim režnjem. U kontrolnoj grupi su izložena alveolarna kost i koren zuba prekriveni transplantatom vezivnog tkiva (TVT) uz koronarno pomereni režanj. Kod obe grupe recesija posmatrani su sledeći parametri: veličina recesije gingive, širina keratinizovane gingive, nivo pripojnog epitela i dubina sondiranja. Parametri su mereni neposredno pre hirurškog zahvata i 12 meseci kasnije. Zabeležen je i indeks zarastanja rane tokom prve tri nedelje posle operacije. Rezultati. Kod obe grupe recesija postignuto je značajno prekrivanje ogoljenog korena zuba (PRF membrana 79,94% i TVT 88,56%; p lt 0,01), dok između dve ispitivane grupe nije uočena statistički značajna razlika. Rezultati ispitivanja širine keratinizovane gingive su pokazali značajno povećanje u obe ispitivane grupe dvanaest meseci nakon hirurškog lečenja (p lt 0,05). Takođe je uočena statistički značajna razlika između posmatranih grupa (p lt 0,05) kod parametra širina keratinizovane gingive. Statističke značajnosti kada je reč o smanjenju nivoa pripojnog epitela i dubine sondiranja, kako u okviru grupa, tako i između obe ispitivane grupe (p>0,05), nije bilo. Merenjem indeksa zarastanja rane uočeni su značajno bolji rezultati u eksperimentalnoj grupi nakon prve i druge nedelje nego u kontrolnoj (p lt 0,05). Zaključak. Oba postupka pokazala su se adekvatnim u lečenju gingivalnih recesija. U kontrolnoj grupi bili su bolji rezultati u dobitku keratinizovanog tkiva, dok se eksperimentalna procedura pokazala jednostavnijom i komfornijom za samog bolesnika, uz značajno bolji postoperacioni tok.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "The use of platelet-rich fibrin membrane in gingival recession treatment, Klinička primena fibrinske membrane u lečenju recesija gingive",
volume = "138",
number = "1-2",
pages = "11-18",
doi = "10.2298/SARH1002011A"
}

Aleksić, Z., Janković, S., Dimitrijević, B., Divnić-Resnik, T., Milinković, I.,& Leković, V.. (2010). The use of platelet-rich fibrin membrane in gingival recession treatment. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 138(1-2), 11-18.
https://doi.org/10.2298/SARH1002011A

Aleksić Z, Janković S, Dimitrijević B, Divnić-Resnik T, Milinković I, Leković V. The use of platelet-rich fibrin membrane in gingival recession treatment. in Srpski arhiv za celokupno lekarstvo. 2010;138(1-2):11-18.
doi:10.2298/SARH1002011A .

Aleksić, Zoran, Janković, Saša, Dimitrijević, Božidar, Divnić-Resnik, Tihana, Milinković, Iva, Leković, Vojislav, "The use of platelet-rich fibrin membrane in gingival recession treatment" in Srpski arhiv za celokupno lekarstvo, 138, no. 1-2 (2010):11-18,
https://doi.org/10.2298/SARH1002011A . .