Perić, Mirjana

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orcid::0000-0003-3667-4253
  • Perić, Mirjana (9)
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Author's Bibliography

Development and validation of mathematical models for testing antifungal activity of different essential oils against Candida species

Perić, Mirjana; Rajković, Katarina; Milić-Lemić, Aleksandra; Živković, Rade; Arsić-Arsenijević, Valentina

(Pergamon-Elsevier Science Ltd, Oxford, 2019)

TY  - JOUR
AU  - Perić, Mirjana
AU  - Rajković, Katarina
AU  - Milić-Lemić, Aleksandra
AU  - Živković, Rade
AU  - Arsić-Arsenijević, Valentina
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2470
AB  - Objective: The upward trend in using plant materials introduced essential oils (EOs) as a valuable, novel, bioactive antifungal agent and as an alternative to standard treatment protocol of denture stomatitis caused by Candida species. Therefore, the aim was to evaluate the antifungal activity of different EOs and to present the response surface methodology (RSM) and artificial neural network (ANN) as possible tools for optimizing and predicting EOs antifungal activity. Methods: Minimum inhibitory concentration (MIC) and Minimum fungicidal concentration (MFC) of the EOs against 3 species Candida spp. (C. albicans, C. tropicalis, C. glabrata) isolated in patients with DS were determined, together with optimization and prediction based on non-terpene and terpene content in EOs, using two mathematical models RSM and ANN-GA. Results: The highest concentrations of EO M. alternifolia inhibited (1.6-2.8 mu g/ml) and fungicided (3.5-6.0 mu g/ml) all three investigated Candida spp, while the lowest concentrations of EO C. Limon inhibited (0.2-0.5 mu g/ml) and fungicided (0.6-1.1 mu g/ml). Among the three types of Candida, C. glabrata was the most sensitive. The RSM modelling proved that MICs and MFCs statistically depend on non-terpene and terpene content in different EOs ( lt  0.0001). Both models showed that a citrus oil (EO C. Limon) with 89% content of terpenes and limonene as major constituent was more antifungal efficient. Conclusions: The investigated EOs showed a broad spectrum of anticandidal activity, also confirmed using the RSM and ANN-GA models. Since EOs can be cytotoxic in higher concentrations, models may be used for qualitative and quantitative dosage predictions of the antifungal activity of EOs.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Archives of Oral Biology
T1  - Development and validation of mathematical models for testing antifungal activity of different essential oils against Candida species
VL  - 98
SP  - 258
EP  - 264
DO  - 10.1016/j.archoralbio.2018.11.029
ER  - 
@article{
author = "Perić, Mirjana and Rajković, Katarina and Milić-Lemić, Aleksandra and Živković, Rade and Arsić-Arsenijević, Valentina",
year = "2019",
abstract = "Objective: The upward trend in using plant materials introduced essential oils (EOs) as a valuable, novel, bioactive antifungal agent and as an alternative to standard treatment protocol of denture stomatitis caused by Candida species. Therefore, the aim was to evaluate the antifungal activity of different EOs and to present the response surface methodology (RSM) and artificial neural network (ANN) as possible tools for optimizing and predicting EOs antifungal activity. Methods: Minimum inhibitory concentration (MIC) and Minimum fungicidal concentration (MFC) of the EOs against 3 species Candida spp. (C. albicans, C. tropicalis, C. glabrata) isolated in patients with DS were determined, together with optimization and prediction based on non-terpene and terpene content in EOs, using two mathematical models RSM and ANN-GA. Results: The highest concentrations of EO M. alternifolia inhibited (1.6-2.8 mu g/ml) and fungicided (3.5-6.0 mu g/ml) all three investigated Candida spp, while the lowest concentrations of EO C. Limon inhibited (0.2-0.5 mu g/ml) and fungicided (0.6-1.1 mu g/ml). Among the three types of Candida, C. glabrata was the most sensitive. The RSM modelling proved that MICs and MFCs statistically depend on non-terpene and terpene content in different EOs ( lt  0.0001). Both models showed that a citrus oil (EO C. Limon) with 89% content of terpenes and limonene as major constituent was more antifungal efficient. Conclusions: The investigated EOs showed a broad spectrum of anticandidal activity, also confirmed using the RSM and ANN-GA models. Since EOs can be cytotoxic in higher concentrations, models may be used for qualitative and quantitative dosage predictions of the antifungal activity of EOs.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Archives of Oral Biology",
title = "Development and validation of mathematical models for testing antifungal activity of different essential oils against Candida species",
volume = "98",
pages = "258-264",
doi = "10.1016/j.archoralbio.2018.11.029"
}
Perić, M., Rajković, K., Milić-Lemić, A., Živković, R.,& Arsić-Arsenijević, V.. (2019). Development and validation of mathematical models for testing antifungal activity of different essential oils against Candida species. in Archives of Oral Biology
Pergamon-Elsevier Science Ltd, Oxford., 98, 258-264.
https://doi.org/10.1016/j.archoralbio.2018.11.029
Perić M, Rajković K, Milić-Lemić A, Živković R, Arsić-Arsenijević V. Development and validation of mathematical models for testing antifungal activity of different essential oils against Candida species. in Archives of Oral Biology. 2019;98:258-264.
doi:10.1016/j.archoralbio.2018.11.029 .
Perić, Mirjana, Rajković, Katarina, Milić-Lemić, Aleksandra, Živković, Rade, Arsić-Arsenijević, Valentina, "Development and validation of mathematical models for testing antifungal activity of different essential oils against Candida species" in Archives of Oral Biology, 98 (2019):258-264,
https://doi.org/10.1016/j.archoralbio.2018.11.029 . .
1
8
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Laboratory-Based Investigation of Denture Sonication Method in Patients with Candida-Associated Denture Stomatitis

Perić, Mirjana; Radunović, Milena; Pekmezović, Marina; Marinković, Jelena; Živković, Rade; Arsić-Arsenijević, Valentina

(Wiley, Hoboken, 2019)

TY  - JOUR
AU  - Perić, Mirjana
AU  - Radunović, Milena
AU  - Pekmezović, Marina
AU  - Marinković, Jelena
AU  - Živković, Rade
AU  - Arsić-Arsenijević, Valentina
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2379
AB  - Purpose Denture stomatitis (DS) is a disease characterized by inflammation and erythema of the oral mucosa areas covered by the denture. Multifactorial etiological factors contribute to DS, but it seems that Candida plays the key role. The aim of the study was to evaluate the denture sonication method to: (i) increase the possibility of diagnosing patients with Candida-associated DS; (ii) detect and identify the mixed Candida spp., and (iii) determine the Candida colony forming units (CFU) and its possible relationship with DS severity, based on Newton's classification. Materials and Methods The cross-sectional study conducted at the Clinic for Dental Prosthetics, Belgrade (Serbia) from June 2013 to December 2014 enrolled edentulous patients with dentures (n = 250). Patients without DS (n = 20) were the control group (CG). The patients' data were collected, and patients with DS (study group/SG) were selected and divided into SG Candida+ and SG Candida-. Based on severity of DS, the SG patients were classified in 3 groups (Newton's classification). Four sampling methods were applied to detect patients with Candida-associated DS: mucosa swab, denture swab, oral rinse, and denture sonication method. The sensitivity and specificity of denture sonication method were shown using the receiver operating characteristic (ROC) curve and the area under the curve (AUC). Results In 97 (38.8%), out of 250 clinically examined patients, DS was diagnosed. In 82 (84.5%), out of 97 mycologically examined patients, Candida-associated DS was detected when denture sonication method was applied. Additionally, using the denture sonication method we observed: (i) the largest number of Candida positive patients compared to other sampling methods (p  lt  0.0001); (ii) the highest number of Candida CFU/ml (10(5)), and (iii) the possibility to detect mixed Candida cultures. The largest number of patients with Candida-associated DS showed type II (60%) DS, followed by type I (21%), and type III (19%) DS. Conclusion The denture sonication method is easy, accurate, and sensitive, and increases the possibility of diagnosing patients with Candida-associated DS. Additionally, yeast quantification, mixed Candida spp., and non-albicans Candida were detectable when cultivation on Candida CHROMagar was performed. It was not possible using conventional methods, such as swab or oral rinse.
PB  - Wiley, Hoboken
T2  - Journal of Prosthodontics-Implant Esthetic & Reconstructive Dentistry
T1  - Laboratory-Based Investigation of Denture Sonication Method in Patients with Candida-Associated Denture Stomatitis
VL  - 28
IS  - 5
SP  - 580
EP  - 586
DO  - 10.1111/jopr.12610
ER  - 
@article{
author = "Perić, Mirjana and Radunović, Milena and Pekmezović, Marina and Marinković, Jelena and Živković, Rade and Arsić-Arsenijević, Valentina",
year = "2019",
abstract = "Purpose Denture stomatitis (DS) is a disease characterized by inflammation and erythema of the oral mucosa areas covered by the denture. Multifactorial etiological factors contribute to DS, but it seems that Candida plays the key role. The aim of the study was to evaluate the denture sonication method to: (i) increase the possibility of diagnosing patients with Candida-associated DS; (ii) detect and identify the mixed Candida spp., and (iii) determine the Candida colony forming units (CFU) and its possible relationship with DS severity, based on Newton's classification. Materials and Methods The cross-sectional study conducted at the Clinic for Dental Prosthetics, Belgrade (Serbia) from June 2013 to December 2014 enrolled edentulous patients with dentures (n = 250). Patients without DS (n = 20) were the control group (CG). The patients' data were collected, and patients with DS (study group/SG) were selected and divided into SG Candida+ and SG Candida-. Based on severity of DS, the SG patients were classified in 3 groups (Newton's classification). Four sampling methods were applied to detect patients with Candida-associated DS: mucosa swab, denture swab, oral rinse, and denture sonication method. The sensitivity and specificity of denture sonication method were shown using the receiver operating characteristic (ROC) curve and the area under the curve (AUC). Results In 97 (38.8%), out of 250 clinically examined patients, DS was diagnosed. In 82 (84.5%), out of 97 mycologically examined patients, Candida-associated DS was detected when denture sonication method was applied. Additionally, using the denture sonication method we observed: (i) the largest number of Candida positive patients compared to other sampling methods (p  lt  0.0001); (ii) the highest number of Candida CFU/ml (10(5)), and (iii) the possibility to detect mixed Candida cultures. The largest number of patients with Candida-associated DS showed type II (60%) DS, followed by type I (21%), and type III (19%) DS. Conclusion The denture sonication method is easy, accurate, and sensitive, and increases the possibility of diagnosing patients with Candida-associated DS. Additionally, yeast quantification, mixed Candida spp., and non-albicans Candida were detectable when cultivation on Candida CHROMagar was performed. It was not possible using conventional methods, such as swab or oral rinse.",
publisher = "Wiley, Hoboken",
journal = "Journal of Prosthodontics-Implant Esthetic & Reconstructive Dentistry",
title = "Laboratory-Based Investigation of Denture Sonication Method in Patients with Candida-Associated Denture Stomatitis",
volume = "28",
number = "5",
pages = "580-586",
doi = "10.1111/jopr.12610"
}
Perić, M., Radunović, M., Pekmezović, M., Marinković, J., Živković, R.,& Arsić-Arsenijević, V.. (2019). Laboratory-Based Investigation of Denture Sonication Method in Patients with Candida-Associated Denture Stomatitis. in Journal of Prosthodontics-Implant Esthetic & Reconstructive Dentistry
Wiley, Hoboken., 28(5), 580-586.
https://doi.org/10.1111/jopr.12610
Perić M, Radunović M, Pekmezović M, Marinković J, Živković R, Arsić-Arsenijević V. Laboratory-Based Investigation of Denture Sonication Method in Patients with Candida-Associated Denture Stomatitis. in Journal of Prosthodontics-Implant Esthetic & Reconstructive Dentistry. 2019;28(5):580-586.
doi:10.1111/jopr.12610 .
Perić, Mirjana, Radunović, Milena, Pekmezović, Marina, Marinković, Jelena, Živković, Rade, Arsić-Arsenijević, Valentina, "Laboratory-Based Investigation of Denture Sonication Method in Patients with Candida-Associated Denture Stomatitis" in Journal of Prosthodontics-Implant Esthetic & Reconstructive Dentistry, 28, no. 5 (2019):580-586,
https://doi.org/10.1111/jopr.12610 . .
9
2
9

An anthropometric study of craniofacial measurements and their correlation with vertical dimension of occlusion among fully dentate population in Serbia

Živković, Nikola; Nikolić, Pavle; Kuzmanović-Pfićer, Jovana; Perić, Mirjana; Milić-Lemić, Aleksandra

(Srpsko lekarsko društvo - Stomatološka sekcija, Beograd, 2019)

TY  - JOUR
AU  - Živković, Nikola
AU  - Nikolić, Pavle
AU  - Kuzmanović-Pfićer, Jovana
AU  - Perić, Mirjana
AU  - Milić-Lemić, Aleksandra
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2437
AB  - Introduction In clinical conditions vertical dimension of occlusion (VDO) is defined as a distance between the two points, one above and the other one under the mouth, while teeth are intercuspidated. As a result of teeth loss, attrition , abrasion or unsuccessful dental interventions the VDO changes. Decrease of VDO not only changes the esthetic appereance of the lower third of the face, but also affects the function of the orofacial system. The objective of the study was to find correlation of VDO and craniofacial measurements among fully dentate subjects. Material and methods the study was performed at the Clinic of Prosthodontics of University of Belgrade from October 2018 until March 2019. The participants included both genders age range between 22 and 24 years, class I occlusion and intact dentition. Twelve craniofacial lines were measured with specially constructed divider. Gathered results were analyzed in SPSS 22 computer software. Mean values and standard deviation were used for data description. Results the results showed statistically significant correlation in values of some parameters in both genders. The proportion of the face was noticed among all participants, and possibility of analyzing face by thirds. Also the correlation was noticed between the lower facial height and the height of right ear as well as bi-pupillary distance where with increasing distance of bi-pupillary line, the value of the lower facial height was also increased. Statistical significance in values of both genders was noticed in middle facial height (p = 0.006), lower facial height/ vertical dimension of occlusion (p = 0.004), width of nose (p = 0.01), Frankfurt plane (p = 0.008), height of the right ear (p = 0.000). Conclusion Obtained results showed correlation between VDO and craniofacial dimension among young adults with intact dentition.
AB  - Uvod U kliničkim uslovima vertikalna dimenzija okluzije (VDO) definiše se kao rastojanje gde je jedna tačka lokalizovana iznad, a druga ispod nivoa usana, kada su zubi u maksimalnoj interkuspidaciji. Kao posledica gubitka zuba usled atricije, abrazije, odnosno neuspešnih stomatoloških intervencija VDO se menja i ne utiče samo na estetski izgled donje trećine lica već i na funkciju mastikatornog aparata. Cilj ovog rada bio je da se utvrdi povezanost vrednosti VDO i kraniometrijskih dimenzija kod pacijenata sa intaktnom denticijom. Materijal i metode Ispitivanje je sprovedeno na Klinici za Stomatološku protetiku Univerziteta u Beogradu i trajalo je od oktobra 2018. do marta 2019. godine. Ispitanici su bili muškog i ženskog pola, prosečne starosti između 22 i 24 godine, I skeletne klase i intaktne denticije. Dvanaest kraniometrijskih linija je izmereno korišćenjem specijalno izrađenog šestara. Prikupljeni rezultati su analizirani u kompjuterskom programu SPSS 22. Prosek i standardna devijacija su korišćeni za deskripciju podataka, a Spirmanova korelacija za utvrđivanje povezanosti između parametara. Rezultati Rezultati su pokazali statistički značajnu povezanost kraniometrijskih linija kod osoba oba pola. Uočena je skladnost lica ispitanika, i mogućnost analize lica po trećinama. Pokazana je korelacija srednje jačine između donje trećine lica i veličine uveta. Takođe je zapažena korelacija donje trećine lica i bipupilarne linije jer je uočeno da se pri povećanju rastojanja bipupilarne linije povećavala i vrednost donje trećine lica. Statistička značajnost u rezultatima među polovima je uočena kada su u pitanju srednja visina lica (p = 0,006), donja visina lica/vertikalna, dimenzije okluzije (p = 0,004), širine nosa (p = 0,01), Frankfurtske horizontale (p = 0,008), visine desnog uveta (p = 0,000). Zaključak Dobijeni rezultati su pokazali da postoji korelacija VDO i kraniometrijskih dimenzija među pacijentima mlađe životne dobi sa intaktnom denticijom.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - An anthropometric study of craniofacial measurements and their correlation with vertical dimension of occlusion among fully dentate population in Serbia
T1  - Antropometrijska studija kraniofacijalnih dimenzija i njihova korelacija sa vertikalnom dimenzijom okluzije u populaciji Srbije kod pacijenata sa očuvanom denticijom
VL  - 66
IS  - 4
SP  - 182
EP  - 188
DO  - 10.2478/sdj-2019-0019
ER  - 
@article{
author = "Živković, Nikola and Nikolić, Pavle and Kuzmanović-Pfićer, Jovana and Perić, Mirjana and Milić-Lemić, Aleksandra",
year = "2019",
abstract = "Introduction In clinical conditions vertical dimension of occlusion (VDO) is defined as a distance between the two points, one above and the other one under the mouth, while teeth are intercuspidated. As a result of teeth loss, attrition , abrasion or unsuccessful dental interventions the VDO changes. Decrease of VDO not only changes the esthetic appereance of the lower third of the face, but also affects the function of the orofacial system. The objective of the study was to find correlation of VDO and craniofacial measurements among fully dentate subjects. Material and methods the study was performed at the Clinic of Prosthodontics of University of Belgrade from October 2018 until March 2019. The participants included both genders age range between 22 and 24 years, class I occlusion and intact dentition. Twelve craniofacial lines were measured with specially constructed divider. Gathered results were analyzed in SPSS 22 computer software. Mean values and standard deviation were used for data description. Results the results showed statistically significant correlation in values of some parameters in both genders. The proportion of the face was noticed among all participants, and possibility of analyzing face by thirds. Also the correlation was noticed between the lower facial height and the height of right ear as well as bi-pupillary distance where with increasing distance of bi-pupillary line, the value of the lower facial height was also increased. Statistical significance in values of both genders was noticed in middle facial height (p = 0.006), lower facial height/ vertical dimension of occlusion (p = 0.004), width of nose (p = 0.01), Frankfurt plane (p = 0.008), height of the right ear (p = 0.000). Conclusion Obtained results showed correlation between VDO and craniofacial dimension among young adults with intact dentition., Uvod U kliničkim uslovima vertikalna dimenzija okluzije (VDO) definiše se kao rastojanje gde je jedna tačka lokalizovana iznad, a druga ispod nivoa usana, kada su zubi u maksimalnoj interkuspidaciji. Kao posledica gubitka zuba usled atricije, abrazije, odnosno neuspešnih stomatoloških intervencija VDO se menja i ne utiče samo na estetski izgled donje trećine lica već i na funkciju mastikatornog aparata. Cilj ovog rada bio je da se utvrdi povezanost vrednosti VDO i kraniometrijskih dimenzija kod pacijenata sa intaktnom denticijom. Materijal i metode Ispitivanje je sprovedeno na Klinici za Stomatološku protetiku Univerziteta u Beogradu i trajalo je od oktobra 2018. do marta 2019. godine. Ispitanici su bili muškog i ženskog pola, prosečne starosti između 22 i 24 godine, I skeletne klase i intaktne denticije. Dvanaest kraniometrijskih linija je izmereno korišćenjem specijalno izrađenog šestara. Prikupljeni rezultati su analizirani u kompjuterskom programu SPSS 22. Prosek i standardna devijacija su korišćeni za deskripciju podataka, a Spirmanova korelacija za utvrđivanje povezanosti između parametara. Rezultati Rezultati su pokazali statistički značajnu povezanost kraniometrijskih linija kod osoba oba pola. Uočena je skladnost lica ispitanika, i mogućnost analize lica po trećinama. Pokazana je korelacija srednje jačine između donje trećine lica i veličine uveta. Takođe je zapažena korelacija donje trećine lica i bipupilarne linije jer je uočeno da se pri povećanju rastojanja bipupilarne linije povećavala i vrednost donje trećine lica. Statistička značajnost u rezultatima među polovima je uočena kada su u pitanju srednja visina lica (p = 0,006), donja visina lica/vertikalna, dimenzije okluzije (p = 0,004), širine nosa (p = 0,01), Frankfurtske horizontale (p = 0,008), visine desnog uveta (p = 0,000). Zaključak Dobijeni rezultati su pokazali da postoji korelacija VDO i kraniometrijskih dimenzija među pacijentima mlađe životne dobi sa intaktnom denticijom.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "An anthropometric study of craniofacial measurements and their correlation with vertical dimension of occlusion among fully dentate population in Serbia, Antropometrijska studija kraniofacijalnih dimenzija i njihova korelacija sa vertikalnom dimenzijom okluzije u populaciji Srbije kod pacijenata sa očuvanom denticijom",
volume = "66",
number = "4",
pages = "182-188",
doi = "10.2478/sdj-2019-0019"
}
Živković, N., Nikolić, P., Kuzmanović-Pfićer, J., Perić, M.,& Milić-Lemić, A.. (2019). An anthropometric study of craniofacial measurements and their correlation with vertical dimension of occlusion among fully dentate population in Serbia. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 66(4), 182-188.
https://doi.org/10.2478/sdj-2019-0019
Živković N, Nikolić P, Kuzmanović-Pfićer J, Perić M, Milić-Lemić A. An anthropometric study of craniofacial measurements and their correlation with vertical dimension of occlusion among fully dentate population in Serbia. in Stomatološki glasnik Srbije. 2019;66(4):182-188.
doi:10.2478/sdj-2019-0019 .
Živković, Nikola, Nikolić, Pavle, Kuzmanović-Pfićer, Jovana, Perić, Mirjana, Milić-Lemić, Aleksandra, "An anthropometric study of craniofacial measurements and their correlation with vertical dimension of occlusion among fully dentate population in Serbia" in Stomatološki glasnik Srbije, 66, no. 4 (2019):182-188,
https://doi.org/10.2478/sdj-2019-0019 . .

The severity of denture stomatitis as related to risk factors and different Candida spp.

Perić, Mirjana; Živković, Rade; Milić-Lemić, Aleksandra; Radunović, Milena; Miličić, Biljana; Arsić-Arsenijević, Valentina

(Elsevier Science Inc, New York, 2018)

TY  - JOUR
AU  - Perić, Mirjana
AU  - Živković, Rade
AU  - Milić-Lemić, Aleksandra
AU  - Radunović, Milena
AU  - Miličić, Biljana
AU  - Arsić-Arsenijević, Valentina
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2298
AB  - Objectives. 1) To select patients with Candida-related denture stomatitis (DS) and to study possible risk factors associated with DS, 2) to evaluate the severity of DS according to Newton's classification, and 3) to investigate the association between the presence of non-albicans Candida spp. (NAC) or mixed Candida spp. and the severity of DS. Study Design. Eighty-two patients with Candida-positive DS have undergone 1) filling in the interview questionnaire, 2) clinical examination, and 3) microbiologic examination. Results. A total of 113 Candida spp. isolates were obtained from Candida-positive DS patients: C. albicans (as a single species) in 47/82 (57%) patients (study group A [SG_A]) and NAC/mixed Candida spp. in 35/82 (43%) patients (SG_B). Univariate logistic regression analysis showed that older age, longer age of the mandibular denture, and ex-smoker status were associated with SG_A. A multivariate model revealed no significant predictor of DS severity. Patients from SG_A were 3 times as likely to have DS type I, while patients from SG_B were 4.9 times as likely to have DS type III. Conclusions. Our results show the association between type III of DS (by Newton's classification) and the presence of NAC or mixed Candida spp. in denture wearers.
PB  - Elsevier Science Inc, New York
T2  - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology
T1  - The severity of denture stomatitis as related to risk factors and different Candida spp.
VL  - 126
IS  - 1
SP  - 41
EP  - 47
DO  - 10.1016/j.oooo.2018.03.003
ER  - 
@article{
author = "Perić, Mirjana and Živković, Rade and Milić-Lemić, Aleksandra and Radunović, Milena and Miličić, Biljana and Arsić-Arsenijević, Valentina",
year = "2018",
abstract = "Objectives. 1) To select patients with Candida-related denture stomatitis (DS) and to study possible risk factors associated with DS, 2) to evaluate the severity of DS according to Newton's classification, and 3) to investigate the association between the presence of non-albicans Candida spp. (NAC) or mixed Candida spp. and the severity of DS. Study Design. Eighty-two patients with Candida-positive DS have undergone 1) filling in the interview questionnaire, 2) clinical examination, and 3) microbiologic examination. Results. A total of 113 Candida spp. isolates were obtained from Candida-positive DS patients: C. albicans (as a single species) in 47/82 (57%) patients (study group A [SG_A]) and NAC/mixed Candida spp. in 35/82 (43%) patients (SG_B). Univariate logistic regression analysis showed that older age, longer age of the mandibular denture, and ex-smoker status were associated with SG_A. A multivariate model revealed no significant predictor of DS severity. Patients from SG_A were 3 times as likely to have DS type I, while patients from SG_B were 4.9 times as likely to have DS type III. Conclusions. Our results show the association between type III of DS (by Newton's classification) and the presence of NAC or mixed Candida spp. in denture wearers.",
publisher = "Elsevier Science Inc, New York",
journal = "Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology",
title = "The severity of denture stomatitis as related to risk factors and different Candida spp.",
volume = "126",
number = "1",
pages = "41-47",
doi = "10.1016/j.oooo.2018.03.003"
}
Perić, M., Živković, R., Milić-Lemić, A., Radunović, M., Miličić, B.,& Arsić-Arsenijević, V.. (2018). The severity of denture stomatitis as related to risk factors and different Candida spp.. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology
Elsevier Science Inc, New York., 126(1), 41-47.
https://doi.org/10.1016/j.oooo.2018.03.003
Perić M, Živković R, Milić-Lemić A, Radunović M, Miličić B, Arsić-Arsenijević V. The severity of denture stomatitis as related to risk factors and different Candida spp.. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology. 2018;126(1):41-47.
doi:10.1016/j.oooo.2018.03.003 .
Perić, Mirjana, Živković, Rade, Milić-Lemić, Aleksandra, Radunović, Milena, Miličić, Biljana, Arsić-Arsenijević, Valentina, "The severity of denture stomatitis as related to risk factors and different Candida spp." in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, 126, no. 1 (2018):41-47,
https://doi.org/10.1016/j.oooo.2018.03.003 . .
27
10
23

Evaluation of different sampling methods and the denture sonication methods for recovering Candida in patients with denture stomatitis

Perić, Mirjana

(Wiley, Hoboken, 2017)

TY  - CONF
AU  - Perić, Mirjana
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2216
PB  - Wiley, Hoboken
C3  - Mycoses
T1  - Evaluation of different sampling methods and the denture sonication methods for recovering Candida in patients with denture stomatitis
VL  - 60
SP  - 117
EP  - 117
UR  - https://hdl.handle.net/21.15107/rcub_smile_2216
ER  - 
@conference{
author = "Perić, Mirjana",
year = "2017",
publisher = "Wiley, Hoboken",
journal = "Mycoses",
title = "Evaluation of different sampling methods and the denture sonication methods for recovering Candida in patients with denture stomatitis",
volume = "60",
pages = "117-117",
url = "https://hdl.handle.net/21.15107/rcub_smile_2216"
}
Perić, M.. (2017). Evaluation of different sampling methods and the denture sonication methods for recovering Candida in patients with denture stomatitis. in Mycoses
Wiley, Hoboken., 60, 117-117.
https://hdl.handle.net/21.15107/rcub_smile_2216
Perić M. Evaluation of different sampling methods and the denture sonication methods for recovering Candida in patients with denture stomatitis. in Mycoses. 2017;60:117-117.
https://hdl.handle.net/21.15107/rcub_smile_2216 .
Perić, Mirjana, "Evaluation of different sampling methods and the denture sonication methods for recovering Candida in patients with denture stomatitis" in Mycoses, 60 (2017):117-117,
https://hdl.handle.net/21.15107/rcub_smile_2216 .

Effect of Carisolv gel on sound, demineralized and carious dentin: In vitro study

Eftimoska, Marina; Apostolska, Sonja; Rendzova, Vasilka; Elencevski, Sašo; Popovac, Aleksandra; Perić, Mirjana

(Srpsko lekarsko društvo - Stomatološka sekcija, Beograd, 2015)

TY  - JOUR
AU  - Eftimoska, Marina
AU  - Apostolska, Sonja
AU  - Rendzova, Vasilka
AU  - Elencevski, Sašo
AU  - Popovac, Aleksandra
AU  - Perić, Mirjana
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2062
AB  - Pain and discomfort during dental interventions caused by high-speed dental burs are the most frequent reasons for avoiding dental visits. Numerous possibilities have been offered in the last decade aiming to replace burs for caries removal, one of them is chemo-mechanical method of caries elimination. The aim of this study was to analyze micromorphological changes caused by Carisolv on sound, demineralized and carious (softened) dentin using SEM. Material and Methods Study included 30 teeth (20 intact and 10 with carious lesions) extracted for orthodontic reasons. Carisolv™ system (MediTeam, Sweden) that contains Carisolv gel and specific nickel-titanium hand instruments was used for chemo-mechanical caries elimination. In our study only Carisolv gel was applied on sound, demineralized and carious dentin for 20 min. Dentin surface was analyzed using scanning electronic microscope (SEM). Results SEM showed that Carisolv gel affected soft carious dentin only with no changes on sound dentin regardless of demineralization status. Conclusion Carisolv did not affect sound and demineralized dentin while it selectively dissolved carious dentin.
AB  - Bol i nelagodnost tokom stomatoloških intervencija prouzrokovani svrdlima visokoturažnog kolenjaka najčešći su razlozi za izbegavanje posete stomatologu. Poslednjih godina pojavile su se brojne mogućnosti koje bi izostavile svrdlo kao način uklanjanja karijesa, a jedan od njih je hemijsko- mehanička metoda uklanjanja karijesa. Cilj ovog istraživanja bio je da se analiziraju mikromorfološke promene nastale nakon primene gela Carisolv na zdrav, demineralizovan i karijesno izmenjen dentin pomoću skening- elektronske mikroskopije (SEM). Materijal i metode rada U istraživanju je korišćeno 30 zuba ekstrahovanih iz ortodontskih razloga (20 intaktnih i 10 s karijesnim lezijama). Korišćen je sistem Carisolv ™ (MediTeam, Švedska), materijal za hemijsko- mehaničko uklanjanje karijesa koji je sastoji od gela Carisolv i specifičnih nikl-titanijumskih ručnih instrumenata. U našoj studiji korišćen je samo gel Carisolv, koji je aplikovan na zdrav, demineralizovan i karijesno izmenjen dentin tokom 20 minuta. Skening- elektronski mikroskop je primenjen za analizu površine dentina. Rezultati SEM analiza je pokazala da ovaj gel utiče samo na karijesni dentin, dok na zdrav dentin nije imao nikakvog uticaja bez obzira na stanje demineralizacije. Zaključak Carisolv nije pokazao nikakve promene na zdravom i demineralizovanom dentinu, ali je uticao na selektivno rastvaranje i uklanjanje dentina izmenjenog karijesom.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Effect of Carisolv gel on sound, demineralized and carious dentin: In vitro study
T1  - Uticaj gela Carisolv na zdrav, demineralizovan i karijesno izmenjen dentin - studija in vitro
VL  - 62
IS  - 1
SP  - 21
EP  - 26
DO  - 10.1515/sdj-2015-0003
ER  - 
@article{
author = "Eftimoska, Marina and Apostolska, Sonja and Rendzova, Vasilka and Elencevski, Sašo and Popovac, Aleksandra and Perić, Mirjana",
year = "2015",
abstract = "Pain and discomfort during dental interventions caused by high-speed dental burs are the most frequent reasons for avoiding dental visits. Numerous possibilities have been offered in the last decade aiming to replace burs for caries removal, one of them is chemo-mechanical method of caries elimination. The aim of this study was to analyze micromorphological changes caused by Carisolv on sound, demineralized and carious (softened) dentin using SEM. Material and Methods Study included 30 teeth (20 intact and 10 with carious lesions) extracted for orthodontic reasons. Carisolv™ system (MediTeam, Sweden) that contains Carisolv gel and specific nickel-titanium hand instruments was used for chemo-mechanical caries elimination. In our study only Carisolv gel was applied on sound, demineralized and carious dentin for 20 min. Dentin surface was analyzed using scanning electronic microscope (SEM). Results SEM showed that Carisolv gel affected soft carious dentin only with no changes on sound dentin regardless of demineralization status. Conclusion Carisolv did not affect sound and demineralized dentin while it selectively dissolved carious dentin., Bol i nelagodnost tokom stomatoloških intervencija prouzrokovani svrdlima visokoturažnog kolenjaka najčešći su razlozi za izbegavanje posete stomatologu. Poslednjih godina pojavile su se brojne mogućnosti koje bi izostavile svrdlo kao način uklanjanja karijesa, a jedan od njih je hemijsko- mehanička metoda uklanjanja karijesa. Cilj ovog istraživanja bio je da se analiziraju mikromorfološke promene nastale nakon primene gela Carisolv na zdrav, demineralizovan i karijesno izmenjen dentin pomoću skening- elektronske mikroskopije (SEM). Materijal i metode rada U istraživanju je korišćeno 30 zuba ekstrahovanih iz ortodontskih razloga (20 intaktnih i 10 s karijesnim lezijama). Korišćen je sistem Carisolv ™ (MediTeam, Švedska), materijal za hemijsko- mehaničko uklanjanje karijesa koji je sastoji od gela Carisolv i specifičnih nikl-titanijumskih ručnih instrumenata. U našoj studiji korišćen je samo gel Carisolv, koji je aplikovan na zdrav, demineralizovan i karijesno izmenjen dentin tokom 20 minuta. Skening- elektronski mikroskop je primenjen za analizu površine dentina. Rezultati SEM analiza je pokazala da ovaj gel utiče samo na karijesni dentin, dok na zdrav dentin nije imao nikakvog uticaja bez obzira na stanje demineralizacije. Zaključak Carisolv nije pokazao nikakve promene na zdravom i demineralizovanom dentinu, ali je uticao na selektivno rastvaranje i uklanjanje dentina izmenjenog karijesom.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Effect of Carisolv gel on sound, demineralized and carious dentin: In vitro study, Uticaj gela Carisolv na zdrav, demineralizovan i karijesno izmenjen dentin - studija in vitro",
volume = "62",
number = "1",
pages = "21-26",
doi = "10.1515/sdj-2015-0003"
}
Eftimoska, M., Apostolska, S., Rendzova, V., Elencevski, S., Popovac, A.,& Perić, M.. (2015). Effect of Carisolv gel on sound, demineralized and carious dentin: In vitro study. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 62(1), 21-26.
https://doi.org/10.1515/sdj-2015-0003
Eftimoska M, Apostolska S, Rendzova V, Elencevski S, Popovac A, Perić M. Effect of Carisolv gel on sound, demineralized and carious dentin: In vitro study. in Stomatološki glasnik Srbije. 2015;62(1):21-26.
doi:10.1515/sdj-2015-0003 .
Eftimoska, Marina, Apostolska, Sonja, Rendzova, Vasilka, Elencevski, Sašo, Popovac, Aleksandra, Perić, Mirjana, "Effect of Carisolv gel on sound, demineralized and carious dentin: In vitro study" in Stomatološki glasnik Srbije, 62, no. 1 (2015):21-26,
https://doi.org/10.1515/sdj-2015-0003 . .

Comparative analisys of clinical and microbiological finding in patients with denture stomatitis

Perić, Mirjana

(Univerzitet u Beogradu, Stomatološki fakultet, 2014)

TY  - THES
AU  - Perić, Mirjana
PY  - 2014
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=3116
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:11407/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=1024226702
UR  - http://nardus.mpn.gov.rs/123456789/5761
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/976
AB  - Denture stomatitis is a common disease in patients with dentures. Generally, denture stomatitis is not followed by any symptoms and patients are usually not aware of the disease. Etiology of denture stotmatitis is multifactorial. As a dominant factor is the fungal infection by Candida spp. Complete dentures are susceptible to colonization and biofilm formation of Candida spp. Denture plaque (biofilm) is similar to a dental plaque and it is a reservoir of potential infective microorganisms. Microorganisms in denture plaque, (mostly Candida spp.) are responsible for the emergence of denture stomatitis. A continual swallowing of microorganism from denture plaque exposes patients to a risk of unexpected infection. The most common isolated species of fungus on dentures is C. albicans. There are some general and local contributory factors. The local factors are: trauma of oral mucosa caused by inadequate dentures, continuous dentures wearing, reduced saliva flow, bad dentures hygiene, type of the material dentures are made of, detures’age, poor dentures retention, unbalanced occlusion. The general factors are: diabetes mellitus, smoking, long antibiotics and corticosteroids application and radio or chemotherapy, diet factors, - lack of vitamin B12, foliates and iron, psychotropic medications and hyposalivators. The aim of this research has been to diagnose and designate a frequency of denture stomatitis of fungal etiology and examine antifungal activities of essential oils. For the needs of this research there has been designed a special questionnaire which contains .personal data, medical and stomatological history and data obtained by clinical examination. Clinical examination consisted of inspection of oral cavity on the basis of which a soft tissue inflammation has been diagnosed as well as a degree and location of the inflammation. Analysing the present state of complete dentures in patients’ mouth there has been established a degree of denture retention, preservation of vertical dimension of occlusion and occlusal relations with antagonists...
AB  - Protezni stomatitis je često oboljenje kod pacijenata koji koriste totalne zubne proteze. Uglavnom protezni stomatitis nije praćen simptomima i pacijenti nisu svesni prisutnog oboljenja. Etiologija proteznog stomatitisa je multifaktorijalna. Kao dominantan faktor ističe se infekcija gljivama roda Candida. Totalne zubne proteze podležu kolonizaciji i formiranju biofilma Candida spp. Protezni plak (biofilm) je sličan dentalnom plaku i služi kao rezervoar potencijalno infektivnih mikroorganizama. Mikroorganizmi iz proteznog plaka, (najviše Candida spp.) su odgovorni za nastanak proteznog stomatitisa. Kontinuirano gutanje mikroorganizama iz proteznog plaka izlaže pacijente riziku od neočekivane infekcije. ajčešća izolovana vrsta gljive na protezama je C. albicans. Prisutni su opšti i lokalni kontributivni faktori. Lokalni faktori su: lezije oralne sluzokože uzrokovane neadekvatnim protezama, neprekidno nošenje zubne proteze, smanjen protok pljuvačke, loša higijena zubne proteze, vrsta materijala od koga je izrađena proteza, starost proteze, slaba retencija proteze, neizbalansirana okluzija. Opšti faktori su: diabetes mellitus, pušenje, dugotrajna primena antibiotika i kortikosteroida, radio i hemoterapija, faktori ishrane – nedostatak vitamina B12, folata i gvožđa, psihotropni lekovi, hiposalivatori. Cilj ovog istraživanja je bio da se pouzdano dijagnostikuje i odredi učestalost proteznog stomatitisa gljivične etiologije i ispita antifungalna aktivnost etarskih ulja. Za potrebe ovog istraživanja dizajniran je poseban upitnik, koji sadrži generalije, medicinsku i stomatološku istoriju i podatke dobijene kliničkim pregledom. Klinički pregled se sastojao od inspekcije usne duplje, na osnovu koga se dijagnostikovala inflamacija mekih tkiva, kao i stepen i lokacija inflamacije. Analizom postojećeg stanja totalne zubne proteze u ustima pacijenta utvrđivan je stepen retencije zubne proteze, očuvanost vertikalne dimenzije okluzije i okluzalni odnosi sa antagonistima. Deo istraživanja je sproveden u laboratoriji...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Comparative analisys of clinical and microbiological finding in patients with denture stomatitis
T1  - Komparativna analiza kliničkog i mikrobiološkog nalaza kod pacijenata sa proteznim stomatitisom
UR  - https://hdl.handle.net/21.15107/rcub_nardus_5761
ER  - 
@phdthesis{
author = "Perić, Mirjana",
year = "2014",
abstract = "Denture stomatitis is a common disease in patients with dentures. Generally, denture stomatitis is not followed by any symptoms and patients are usually not aware of the disease. Etiology of denture stotmatitis is multifactorial. As a dominant factor is the fungal infection by Candida spp. Complete dentures are susceptible to colonization and biofilm formation of Candida spp. Denture plaque (biofilm) is similar to a dental plaque and it is a reservoir of potential infective microorganisms. Microorganisms in denture plaque, (mostly Candida spp.) are responsible for the emergence of denture stomatitis. A continual swallowing of microorganism from denture plaque exposes patients to a risk of unexpected infection. The most common isolated species of fungus on dentures is C. albicans. There are some general and local contributory factors. The local factors are: trauma of oral mucosa caused by inadequate dentures, continuous dentures wearing, reduced saliva flow, bad dentures hygiene, type of the material dentures are made of, detures’age, poor dentures retention, unbalanced occlusion. The general factors are: diabetes mellitus, smoking, long antibiotics and corticosteroids application and radio or chemotherapy, diet factors, - lack of vitamin B12, foliates and iron, psychotropic medications and hyposalivators. The aim of this research has been to diagnose and designate a frequency of denture stomatitis of fungal etiology and examine antifungal activities of essential oils. For the needs of this research there has been designed a special questionnaire which contains .personal data, medical and stomatological history and data obtained by clinical examination. Clinical examination consisted of inspection of oral cavity on the basis of which a soft tissue inflammation has been diagnosed as well as a degree and location of the inflammation. Analysing the present state of complete dentures in patients’ mouth there has been established a degree of denture retention, preservation of vertical dimension of occlusion and occlusal relations with antagonists..., Protezni stomatitis je često oboljenje kod pacijenata koji koriste totalne zubne proteze. Uglavnom protezni stomatitis nije praćen simptomima i pacijenti nisu svesni prisutnog oboljenja. Etiologija proteznog stomatitisa je multifaktorijalna. Kao dominantan faktor ističe se infekcija gljivama roda Candida. Totalne zubne proteze podležu kolonizaciji i formiranju biofilma Candida spp. Protezni plak (biofilm) je sličan dentalnom plaku i služi kao rezervoar potencijalno infektivnih mikroorganizama. Mikroorganizmi iz proteznog plaka, (najviše Candida spp.) su odgovorni za nastanak proteznog stomatitisa. Kontinuirano gutanje mikroorganizama iz proteznog plaka izlaže pacijente riziku od neočekivane infekcije. ajčešća izolovana vrsta gljive na protezama je C. albicans. Prisutni su opšti i lokalni kontributivni faktori. Lokalni faktori su: lezije oralne sluzokože uzrokovane neadekvatnim protezama, neprekidno nošenje zubne proteze, smanjen protok pljuvačke, loša higijena zubne proteze, vrsta materijala od koga je izrađena proteza, starost proteze, slaba retencija proteze, neizbalansirana okluzija. Opšti faktori su: diabetes mellitus, pušenje, dugotrajna primena antibiotika i kortikosteroida, radio i hemoterapija, faktori ishrane – nedostatak vitamina B12, folata i gvožđa, psihotropni lekovi, hiposalivatori. Cilj ovog istraživanja je bio da se pouzdano dijagnostikuje i odredi učestalost proteznog stomatitisa gljivične etiologije i ispita antifungalna aktivnost etarskih ulja. Za potrebe ovog istraživanja dizajniran je poseban upitnik, koji sadrži generalije, medicinsku i stomatološku istoriju i podatke dobijene kliničkim pregledom. Klinički pregled se sastojao od inspekcije usne duplje, na osnovu koga se dijagnostikovala inflamacija mekih tkiva, kao i stepen i lokacija inflamacije. Analizom postojećeg stanja totalne zubne proteze u ustima pacijenta utvrđivan je stepen retencije zubne proteze, očuvanost vertikalne dimenzije okluzije i okluzalni odnosi sa antagonistima. Deo istraživanja je sproveden u laboratoriji...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Comparative analisys of clinical and microbiological finding in patients with denture stomatitis, Komparativna analiza kliničkog i mikrobiološkog nalaza kod pacijenata sa proteznim stomatitisom",
url = "https://hdl.handle.net/21.15107/rcub_nardus_5761"
}
Perić, M.. (2014). Comparative analisys of clinical and microbiological finding in patients with denture stomatitis. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_5761
Perić M. Comparative analisys of clinical and microbiological finding in patients with denture stomatitis. 2014;.
https://hdl.handle.net/21.15107/rcub_nardus_5761 .
Perić, Mirjana, "Comparative analisys of clinical and microbiological finding in patients with denture stomatitis" (2014),
https://hdl.handle.net/21.15107/rcub_nardus_5761 .

Susceptibility profile of Candida spp. isolated from humans and dogs with stomatitis to the essential oil of Thymus vulgaris

Živković, Rade; Perić, Mirjana; Arsić-Arsenijević, Valentina; Martinović, Željko; Pekmezović, Marina; Stojić, Ž.; Raičković, Vanja; Đurišić, Slobodan

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2013)

TY  - JOUR
AU  - Živković, Rade
AU  - Perić, Mirjana
AU  - Arsić-Arsenijević, Valentina
AU  - Martinović, Željko
AU  - Pekmezović, Marina
AU  - Stojić, Ž.
AU  - Raičković, Vanja
AU  - Đurišić, Slobodan
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1782
AB  - Candida spp. form a part of human and animal oral cavity flora. However Candida spp. is the main cause of dental related stomatitis in humans and stomatitis in dogs. Stomatitis treatment implies the use of azoles and polyenes to which yeasts build up resistance. The research is directed to the use of natural compounds such as essential oils. The aim of this paper is to define the antifungal activity of thyme oil on 15 clinical strains of Candida spp., isolated from humans and dogs and to determine if there is a difference in susceptibility between human and dog isolates. Sampling in patients with stomatitis was done by swabbing the denture or oral mucosa swab while sampling in dogs was done by swabbing the oral cavity mucosa after stomatitis has been diagnosed. In order to investigate the antifungal activity of thyme oil in vitro, microdilution method was used. Thyme oil expressed antifungal effects on all investigated strains. Also, our data show that the values of minimum fungicide concentration (MFC) and minimum inhibitory concentration (MIC) are lower in human strains. Explanation is that in most cases, stomatitis in humans is asymptomatic and thus not treated, so Candida strains have not developed resistance. On the other hand, stomatitis in dogs is followed by a marked clinical picture and treated is by antimicotics (mostly by azoles), therefore resistant Candida strains are more likely to occur.
AB  - Candida spp. je sastavni deo mikrobioma usne duplje čoveka i psa. Međutim Candida spp. predstavlja glavni uzročnik proteznog stomatitisa kod čoveka i stomatitisa kod psa. Terapija stomatitisa podrazumeva korišćenje azola i poliena na koje poslednjih godina gljivice razvijaju otpornost. Istrživanja se usmeravaju ka primeni prirodnih preparata kao što su etarska ulja. Cilj rada je utvrdi antifungalnu aktivnost ulja timijana na kliničke izolate Candida spp. čoveka i psa, i utvrdi da li postoji razlika u osetljivosti sojeva Candide spp. izolovanih kod čoveka i psa. Uzorkovanje kod pacijenata sa stomatitisom je vršeno brisom proteze ili brisom sluzokože. Kod pasa je uzrokovanje vršeno brisom sluzokože usne duplje kada je dijagnostikovan stomatitis. Zasejani sojevi su in vitro tretirani korišćenjem mikrodilucione metode da bi se utvrdilo da li ulje timijana deluje na kliničke izolate Candida spp. čoveka i psa. Rezultati pokazuju da su vrednosti minimalne fungicidne koncentracije (MFC) i minimalne inhibitorne koncentracije (MIC) manje kod čoveka. Stomatitis je kod ljudi najčešće je asimptomatski, pacijenti se ne podvrgavaju lečenju, pa sojevi Candida spp. nisu razvili rezistenciju na antifungicidne preparate. Kod pasa stomatitis je praćen burnijom kliničkom slikom, leči se antimikoticima (uglavnom azolima) pa je verovatnoća pojave rezistentnih sojeva Candida spp. veća.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - Susceptibility profile of Candida spp. isolated from humans and dogs with stomatitis to the essential oil of Thymus vulgaris
T1  - Osetljivost sojeva Candida spp. izolovanih kod čoveka i psa sa stomatitisom na etarsko ulje timijana
VL  - 63
IS  - 5-6
SP  - 707
EP  - 715
DO  - 10.2298/AVB1306707Z
ER  - 
@article{
author = "Živković, Rade and Perić, Mirjana and Arsić-Arsenijević, Valentina and Martinović, Željko and Pekmezović, Marina and Stojić, Ž. and Raičković, Vanja and Đurišić, Slobodan",
year = "2013",
abstract = "Candida spp. form a part of human and animal oral cavity flora. However Candida spp. is the main cause of dental related stomatitis in humans and stomatitis in dogs. Stomatitis treatment implies the use of azoles and polyenes to which yeasts build up resistance. The research is directed to the use of natural compounds such as essential oils. The aim of this paper is to define the antifungal activity of thyme oil on 15 clinical strains of Candida spp., isolated from humans and dogs and to determine if there is a difference in susceptibility between human and dog isolates. Sampling in patients with stomatitis was done by swabbing the denture or oral mucosa swab while sampling in dogs was done by swabbing the oral cavity mucosa after stomatitis has been diagnosed. In order to investigate the antifungal activity of thyme oil in vitro, microdilution method was used. Thyme oil expressed antifungal effects on all investigated strains. Also, our data show that the values of minimum fungicide concentration (MFC) and minimum inhibitory concentration (MIC) are lower in human strains. Explanation is that in most cases, stomatitis in humans is asymptomatic and thus not treated, so Candida strains have not developed resistance. On the other hand, stomatitis in dogs is followed by a marked clinical picture and treated is by antimicotics (mostly by azoles), therefore resistant Candida strains are more likely to occur., Candida spp. je sastavni deo mikrobioma usne duplje čoveka i psa. Međutim Candida spp. predstavlja glavni uzročnik proteznog stomatitisa kod čoveka i stomatitisa kod psa. Terapija stomatitisa podrazumeva korišćenje azola i poliena na koje poslednjih godina gljivice razvijaju otpornost. Istrživanja se usmeravaju ka primeni prirodnih preparata kao što su etarska ulja. Cilj rada je utvrdi antifungalnu aktivnost ulja timijana na kliničke izolate Candida spp. čoveka i psa, i utvrdi da li postoji razlika u osetljivosti sojeva Candide spp. izolovanih kod čoveka i psa. Uzorkovanje kod pacijenata sa stomatitisom je vršeno brisom proteze ili brisom sluzokože. Kod pasa je uzrokovanje vršeno brisom sluzokože usne duplje kada je dijagnostikovan stomatitis. Zasejani sojevi su in vitro tretirani korišćenjem mikrodilucione metode da bi se utvrdilo da li ulje timijana deluje na kliničke izolate Candida spp. čoveka i psa. Rezultati pokazuju da su vrednosti minimalne fungicidne koncentracije (MFC) i minimalne inhibitorne koncentracije (MIC) manje kod čoveka. Stomatitis je kod ljudi najčešće je asimptomatski, pacijenti se ne podvrgavaju lečenju, pa sojevi Candida spp. nisu razvili rezistenciju na antifungicidne preparate. Kod pasa stomatitis je praćen burnijom kliničkom slikom, leči se antimikoticima (uglavnom azolima) pa je verovatnoća pojave rezistentnih sojeva Candida spp. veća.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "Susceptibility profile of Candida spp. isolated from humans and dogs with stomatitis to the essential oil of Thymus vulgaris, Osetljivost sojeva Candida spp. izolovanih kod čoveka i psa sa stomatitisom na etarsko ulje timijana",
volume = "63",
number = "5-6",
pages = "707-715",
doi = "10.2298/AVB1306707Z"
}
Živković, R., Perić, M., Arsić-Arsenijević, V., Martinović, Ž., Pekmezović, M., Stojić, Ž., Raičković, V.,& Đurišić, S.. (2013). Susceptibility profile of Candida spp. isolated from humans and dogs with stomatitis to the essential oil of Thymus vulgaris. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(5-6), 707-715.
https://doi.org/10.2298/AVB1306707Z
Živković R, Perić M, Arsić-Arsenijević V, Martinović Ž, Pekmezović M, Stojić Ž, Raičković V, Đurišić S. Susceptibility profile of Candida spp. isolated from humans and dogs with stomatitis to the essential oil of Thymus vulgaris. in Acta veterinaria. 2013;63(5-6):707-715.
doi:10.2298/AVB1306707Z .
Živković, Rade, Perić, Mirjana, Arsić-Arsenijević, Valentina, Martinović, Željko, Pekmezović, Marina, Stojić, Ž., Raičković, Vanja, Đurišić, Slobodan, "Susceptibility profile of Candida spp. isolated from humans and dogs with stomatitis to the essential oil of Thymus vulgaris" in Acta veterinaria, 63, no. 5-6 (2013):707-715,
https://doi.org/10.2298/AVB1306707Z . .
1
1
1

Simulation of crack propagation in titanium mini dental implants (MDI)

Grbović, Aleksandar; Rašuo, Boško P.; Vidanović, Nenad D.; Perić, Mirjana

(Univerzitet u Beogradu - Mašinski fakultet, Beograd, 2011)

TY  - JOUR
AU  - Grbović, Aleksandar
AU  - Rašuo, Boško P.
AU  - Vidanović, Nenad D.
AU  - Perić, Mirjana
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1643
AB  - Developments in mini dental implants (MDI) manufacturing are aimed at making them more biocompatible and, at the same time, lighter, more durable and simultaneously safer than the existing implants. But, occasionally, during installation the failure of MDI may occur or cracks may appear, which could lead to the later failure of MDI. In order to understand and assess crack growth in titanium MDI, Finite Element (FE) software packages ANSYS v13 and FRANC3D v5 have been used. Using FRANC3D software different crack sizes and shapes have been modeled and simulations of crack propagations in three-dimensional model of MDI have been performed. Based on simulation results, the approximate fatigue life of damaged MDI was calculated.
AB  - Unapređenja u proizvodnji mini dentalnih implantata (MDI) su uglavnom usmerena ka povećanju njihove biokompatibilnosti i, u isto vreme, izdržljivosti i bezbednosti, ali i ka smanjenju njihovih dimenzija u odnosu na postojeće implantate. Međutim, tokom ugradnje MDI-a može doći do njegovog loma ili nastanka prsline koja kasnije može prouzrokovati lom. Da bi se analiziralo širenje prsline u titanijumskom MDI-u, korišćeni su softveri za primenu metode konačnih elemenata (MKE) ANSYS v13 i FRANC3D v5. Korišćenjem FRANC3D programa izmodelirane su prsline različitih veličina i oblika na 3D geometriji MDI-a i izvršeno je simuliranje njihovog širenja. Na osnovu rezultata simulacije izračunat je približan zamorni vek oštećenog MDI-a.
PB  - Univerzitet u Beogradu - Mašinski fakultet, Beograd
T2  - FME Transactions
T1  - Simulation of crack propagation in titanium mini dental implants (MDI)
T1  - Simulacija širenja prsline u titanijumskim mini dentalnim implantima (MDI)
VL  - 39
IS  - 4
SP  - 165
EP  - 170
UR  - https://hdl.handle.net/21.15107/rcub_smile_1643
ER  - 
@article{
author = "Grbović, Aleksandar and Rašuo, Boško P. and Vidanović, Nenad D. and Perić, Mirjana",
year = "2011",
abstract = "Developments in mini dental implants (MDI) manufacturing are aimed at making them more biocompatible and, at the same time, lighter, more durable and simultaneously safer than the existing implants. But, occasionally, during installation the failure of MDI may occur or cracks may appear, which could lead to the later failure of MDI. In order to understand and assess crack growth in titanium MDI, Finite Element (FE) software packages ANSYS v13 and FRANC3D v5 have been used. Using FRANC3D software different crack sizes and shapes have been modeled and simulations of crack propagations in three-dimensional model of MDI have been performed. Based on simulation results, the approximate fatigue life of damaged MDI was calculated., Unapređenja u proizvodnji mini dentalnih implantata (MDI) su uglavnom usmerena ka povećanju njihove biokompatibilnosti i, u isto vreme, izdržljivosti i bezbednosti, ali i ka smanjenju njihovih dimenzija u odnosu na postojeće implantate. Međutim, tokom ugradnje MDI-a može doći do njegovog loma ili nastanka prsline koja kasnije može prouzrokovati lom. Da bi se analiziralo širenje prsline u titanijumskom MDI-u, korišćeni su softveri za primenu metode konačnih elemenata (MKE) ANSYS v13 i FRANC3D v5. Korišćenjem FRANC3D programa izmodelirane su prsline različitih veličina i oblika na 3D geometriji MDI-a i izvršeno je simuliranje njihovog širenja. Na osnovu rezultata simulacije izračunat je približan zamorni vek oštećenog MDI-a.",
publisher = "Univerzitet u Beogradu - Mašinski fakultet, Beograd",
journal = "FME Transactions",
title = "Simulation of crack propagation in titanium mini dental implants (MDI), Simulacija širenja prsline u titanijumskim mini dentalnim implantima (MDI)",
volume = "39",
number = "4",
pages = "165-170",
url = "https://hdl.handle.net/21.15107/rcub_smile_1643"
}
Grbović, A., Rašuo, B. P., Vidanović, N. D.,& Perić, M.. (2011). Simulation of crack propagation in titanium mini dental implants (MDI). in FME Transactions
Univerzitet u Beogradu - Mašinski fakultet, Beograd., 39(4), 165-170.
https://hdl.handle.net/21.15107/rcub_smile_1643
Grbović A, Rašuo BP, Vidanović ND, Perić M. Simulation of crack propagation in titanium mini dental implants (MDI). in FME Transactions. 2011;39(4):165-170.
https://hdl.handle.net/21.15107/rcub_smile_1643 .
Grbović, Aleksandar, Rašuo, Boško P., Vidanović, Nenad D., Perić, Mirjana, "Simulation of crack propagation in titanium mini dental implants (MDI)" in FME Transactions, 39, no. 4 (2011):165-170,
https://hdl.handle.net/21.15107/rcub_smile_1643 .
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