TY  - JOUR
AU  - Andrić, Miroslav
AU  - Dožić, Branko
AU  - Popović, Branka
AU  - Stefanović, D.
AU  - Basta-Jovanović, Gordana
AU  - Đogo, N.
AU  - Andjus, P.
AU  - Milašin, Jelena
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1531
AB  - Objectives: The aim of this study was to investigate the expression of survivin, an inhibitor of apoptosis, in odontogenic keratocysts and to compare it to the findings in non-neoplastic jaw cysts - periapical cysts, as well as to establish a possible relationship between survivin expression and human cytomegalovirus presence within these cysts. Materials and methods: Samples of 10 odontogenic keratocysts (five positive and five negative for the presence of cytomegalovirus, as determined by polymerase chain reaction) and 10 periapical cysts (five positive and five negative for the cytomegalovirus presence) were analysed. The expression of survivin was assessed by immunohistochemical methods, using monoclonal antibody that selectively recognizes the cytoplasmic form of survivin. Results: All 10 odontogenic keratocysts showed immunostaining for survivin, while all 10 periapical cysts were negative for its presence. There was no correlation between cytomegalovirus presence and expression of survivin within odontogenic keratocysts. Conclusion: Survivin may contribute to the aggressive behavior of odontogenic keratocysts, and thus support the emerging opinion of their neoplastic nature.
PB  - Wiley, Hoboken
T2  - Oral Diseases
T1  - Survivin expression in odontogenic keratocysts and correlation with cytomegalovirus infection
VL  - 16
IS  - 2
SP  - 156
EP  - 159
DO  - 10.1111/j.1601-0825.2009.01612.x
ER  - 

@article{
author = "Andrić, Miroslav and Dožić, Branko and Popović, Branka and Stefanović, D. and Basta-Jovanović, Gordana and Đogo, N. and Andjus, P. and Milašin, Jelena",
year = "2010",
abstract = "Objectives: The aim of this study was to investigate the expression of survivin, an inhibitor of apoptosis, in odontogenic keratocysts and to compare it to the findings in non-neoplastic jaw cysts - periapical cysts, as well as to establish a possible relationship between survivin expression and human cytomegalovirus presence within these cysts. Materials and methods: Samples of 10 odontogenic keratocysts (five positive and five negative for the presence of cytomegalovirus, as determined by polymerase chain reaction) and 10 periapical cysts (five positive and five negative for the cytomegalovirus presence) were analysed. The expression of survivin was assessed by immunohistochemical methods, using monoclonal antibody that selectively recognizes the cytoplasmic form of survivin. Results: All 10 odontogenic keratocysts showed immunostaining for survivin, while all 10 periapical cysts were negative for its presence. There was no correlation between cytomegalovirus presence and expression of survivin within odontogenic keratocysts. Conclusion: Survivin may contribute to the aggressive behavior of odontogenic keratocysts, and thus support the emerging opinion of their neoplastic nature.",
publisher = "Wiley, Hoboken",
journal = "Oral Diseases",
title = "Survivin expression in odontogenic keratocysts and correlation with cytomegalovirus infection",
volume = "16",
number = "2",
pages = "156-159",
doi = "10.1111/j.1601-0825.2009.01612.x"
}

Andrić, M., Dožić, B., Popović, B., Stefanović, D., Basta-Jovanović, G., Đogo, N., Andjus, P.,& Milašin, J.. (2010). Survivin expression in odontogenic keratocysts and correlation with cytomegalovirus infection. in Oral Diseases
Wiley, Hoboken., 16(2), 156-159.
https://doi.org/10.1111/j.1601-0825.2009.01612.x

Andrić M, Dožić B, Popović B, Stefanović D, Basta-Jovanović G, Đogo N, Andjus P, Milašin J. Survivin expression in odontogenic keratocysts and correlation with cytomegalovirus infection. in Oral Diseases. 2010;16(2):156-159.
doi:10.1111/j.1601-0825.2009.01612.x .

Andrić, Miroslav, Dožić, Branko, Popović, Branka, Stefanović, D., Basta-Jovanović, Gordana, Đogo, N., Andjus, P., Milašin, Jelena, "Survivin expression in odontogenic keratocysts and correlation with cytomegalovirus infection" in Oral Diseases, 16, no. 2 (2010):156-159,
https://doi.org/10.1111/j.1601-0825.2009.01612.x . .

TY  - JOUR
AU  - Milašin, Jelena
AU  - Buffo, Annalisa
AU  - Carulli, Daniela
AU  - Andjus, P
AU  - Strata, Piergiorgio
PY  - 2005
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1245
AB  - The mitogen-activated protein kinases (MAPKs) are a family of signal transduction mediators that regulate a number of cellular activities, including cell growth and proliferation, differentiation and survival, via phosphorylation (activation) of protein kinases. MAPKs are also recruited during synaptic plasticity and remodeling. In the present study we used Western blotting and immunohistochemistry to examine the effects of harmaline administration on the phosphorylation state of three MAPKs: the extracellular signalregulated kinase (ERK1/2), c-jun-N-terminal kinase/stress-activated protein kinase (JNK/SAPK), and p38 MAPK. Harmaline is a tremorigenic drug known to induce enhanced and rhythmic firing of the inferior olive. In rats, synchronous activity of the inferior olive cells induced by harmaline administered for four days from postnatal day 9 to 12 resulted in prolonged maintenance of polyinnervation of Purkinje cells by climbing fibers (axons of olivary cells). Immunohistochemistry showed small but sustained cytoplasmic positivity to phospho-ERK in Purkinje cells and a strong signal for phospho-ERK in the "pinceaux," terminals of the interneuronal basket cells onto Purkinje cells. A similar pattern was observed for JNK/SAPK, while no changes in p38 were noticed. Thus, it was revealed that the activation of two members of the MAPK family in these inhibitory presynaptic terminals is also one consequence of synchronous olivary input to Purkinje cells known to affect developmental plasticity.
PB  - New York Acad Sciences, New York
T2  - Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus
T1  - MAPK activation in cerebellar basket cell terminals after harmaline treatment
VL  - 1048
SP  - 411
EP  - 417
DO  - 10.1196/annals.1342.051
ER  - 

@article{
author = "Milašin, Jelena and Buffo, Annalisa and Carulli, Daniela and Andjus, P and Strata, Piergiorgio",
year = "2005",
abstract = "The mitogen-activated protein kinases (MAPKs) are a family of signal transduction mediators that regulate a number of cellular activities, including cell growth and proliferation, differentiation and survival, via phosphorylation (activation) of protein kinases. MAPKs are also recruited during synaptic plasticity and remodeling. In the present study we used Western blotting and immunohistochemistry to examine the effects of harmaline administration on the phosphorylation state of three MAPKs: the extracellular signalregulated kinase (ERK1/2), c-jun-N-terminal kinase/stress-activated protein kinase (JNK/SAPK), and p38 MAPK. Harmaline is a tremorigenic drug known to induce enhanced and rhythmic firing of the inferior olive. In rats, synchronous activity of the inferior olive cells induced by harmaline administered for four days from postnatal day 9 to 12 resulted in prolonged maintenance of polyinnervation of Purkinje cells by climbing fibers (axons of olivary cells). Immunohistochemistry showed small but sustained cytoplasmic positivity to phospho-ERK in Purkinje cells and a strong signal for phospho-ERK in the "pinceaux," terminals of the interneuronal basket cells onto Purkinje cells. A similar pattern was observed for JNK/SAPK, while no changes in p38 were noticed. Thus, it was revealed that the activation of two members of the MAPK family in these inhibitory presynaptic terminals is also one consequence of synchronous olivary input to Purkinje cells known to affect developmental plasticity.",
publisher = "New York Acad Sciences, New York",
journal = "Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus",
title = "MAPK activation in cerebellar basket cell terminals after harmaline treatment",
volume = "1048",
pages = "411-417",
doi = "10.1196/annals.1342.051"
}

Milašin, J., Buffo, A., Carulli, D., Andjus, P.,& Strata, P.. (2005). MAPK activation in cerebellar basket cell terminals after harmaline treatment. in Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus
New York Acad Sciences, New York., 1048, 411-417.
https://doi.org/10.1196/annals.1342.051

Milašin J, Buffo A, Carulli D, Andjus P, Strata P. MAPK activation in cerebellar basket cell terminals after harmaline treatment. in Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus. 2005;1048:411-417.
doi:10.1196/annals.1342.051 .

Milašin, Jelena, Buffo, Annalisa, Carulli, Daniela, Andjus, P, Strata, Piergiorgio, "MAPK activation in cerebellar basket cell terminals after harmaline treatment" in Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus, 1048 (2005):411-417,
https://doi.org/10.1196/annals.1342.051 . .