Janović, Nataša

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  • Janović, Nataša (3)
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Author's Bibliography

Relationship between nasal septum morphology and nasal obstruction symptom severity: computed tomography study

Janović, Nataša; Janović, Aleksa; Miličić, Biljana; Đurić, Marija

(Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2022)

TY  - JOUR
AU  - Janović, Nataša
AU  - Janović, Aleksa
AU  - Miličić, Biljana
AU  - Đurić, Marija
PY  - 2022
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/3293
AB  - Introduction
The impact of the nasal septum morphology on the severity of obstruction symptoms has not been fully explored.

Objective
This study aimed to investigate whether the morphology of the deviated nasal septum assessed by computed tomography may explain nasal obstruction severity.

Methods
The study included 386 patients who were referred to the computed tomography examination of the paranasal sinuses. Patient selection criteria were the absence of facial anomalies, facial trauma, nasal surgery, and sinonasal tumors. Computed tomography images were used to estimate deviated nasal septum prevalence, the prevalence of Mladina's seven types of deviated nasal septum, and to measure the deviated nasal septum angle. Nasal obstruction severity was assessed by the nasal obstruction symptom evaluation, NOSE scale. The relationship between NOSE score, deviated nasal septum morphology, and deviated nasal septum angle was performed by a statistical regression model on the reduced sample of 225 patients.

Results
The prevalence of deviated nasal septum was 92.7%. Type 7 deviated nasal septum was the most frequent (34.2%) followed by type 5 (26.2%) and type 3 (23.6%). The worst NOSE scores were recorded in the type 2 deviated nasal septum (45.00 ± 28.28). The mean deviated nasal septum angle in patients with nasal obstruction was 8.5° ± 3.24. NOSE scores were not significantly associated with deviated nasal septum types and angles.

Conclusion
Patients with different types of deviated nasal septum have different NOSE scores. Computed tomography morphology of the deviated nasal septum could not fully explain the severity of nasal obstruction.
PB  - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
T2  - BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY
T1  - Relationship between nasal septum morphology and nasal obstruction symptom severity: computed tomography study
VL  - 88
IS  - 5
SP  - 663
EP  - 668
DO  - https://doi.org/10.1016/j.bjorl.2020.09.004
ER  - 
@article{
author = "Janović, Nataša and Janović, Aleksa and Miličić, Biljana and Đurić, Marija",
year = "2022",
abstract = "Introduction
The impact of the nasal septum morphology on the severity of obstruction symptoms has not been fully explored.

Objective
This study aimed to investigate whether the morphology of the deviated nasal septum assessed by computed tomography may explain nasal obstruction severity.

Methods
The study included 386 patients who were referred to the computed tomography examination of the paranasal sinuses. Patient selection criteria were the absence of facial anomalies, facial trauma, nasal surgery, and sinonasal tumors. Computed tomography images were used to estimate deviated nasal septum prevalence, the prevalence of Mladina's seven types of deviated nasal septum, and to measure the deviated nasal septum angle. Nasal obstruction severity was assessed by the nasal obstruction symptom evaluation, NOSE scale. The relationship between NOSE score, deviated nasal septum morphology, and deviated nasal septum angle was performed by a statistical regression model on the reduced sample of 225 patients.

Results
The prevalence of deviated nasal septum was 92.7%. Type 7 deviated nasal septum was the most frequent (34.2%) followed by type 5 (26.2%) and type 3 (23.6%). The worst NOSE scores were recorded in the type 2 deviated nasal septum (45.00 ± 28.28). The mean deviated nasal septum angle in patients with nasal obstruction was 8.5° ± 3.24. NOSE scores were not significantly associated with deviated nasal septum types and angles.

Conclusion
Patients with different types of deviated nasal septum have different NOSE scores. Computed tomography morphology of the deviated nasal septum could not fully explain the severity of nasal obstruction.",
publisher = "Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial",
journal = "BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY",
title = "Relationship between nasal septum morphology and nasal obstruction symptom severity: computed tomography study",
volume = "88",
number = "5",
pages = "663-668",
doi = "https://doi.org/10.1016/j.bjorl.2020.09.004"
}
Janović, N., Janović, A., Miličić, B.,& Đurić, M.. (2022). Relationship between nasal septum morphology and nasal obstruction symptom severity: computed tomography study. in BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial., 88(5), 663-668.
https://doi.org/https://doi.org/10.1016/j.bjorl.2020.09.004
Janović N, Janović A, Miličić B, Đurić M. Relationship between nasal septum morphology and nasal obstruction symptom severity: computed tomography study. in BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY. 2022;88(5):663-668.
doi:https://doi.org/10.1016/j.bjorl.2020.09.004 .
Janović, Nataša, Janović, Aleksa, Miličić, Biljana, Đurić, Marija, "Relationship between nasal septum morphology and nasal obstruction symptom severity: computed tomography study" in BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, 88, no. 5 (2022):663-668,
https://doi.org/https://doi.org/10.1016/j.bjorl.2020.09.004 . .
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Is Computed Tomography Imaging of Deviated Nasal Septum Justified for Obstruction Confirmation?

Janović, Nataša; Janović, Aleksa; Miličić, Biljana; Đurić, Marija

(SAGE, 2021)

TY  - JOUR
AU  - Janović, Nataša
AU  - Janović, Aleksa
AU  - Miličić, Biljana
AU  - Đurić, Marija
PY  - 2021
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/3294
AB  - Third-party payers request objective confirmation of the nasal septum deviation (NSD) severity by computed tomography (CT) before authorizing financial support for septoplasty. Previous studies have provided contradictory results related to the link between obstruction severity and CT-measured angle of the NSD. The aim of this study was to investigate whether the diverse CT morphology of NSDs (including previously neglected types and shapes) could predict obstruction severity. The study included 225 patients with NSD. The CT morphology of the septum was analyzed using 5 different classifications of NSD that are commonly used in the clinical practice and research. The angle of NSD was also measured. Nasal obstruction was assessed by the Nasal Obstruction Symptom Evaluation (NOSE) questionnaire. A relationship between CT morphology and the angle of the NSD and NOSE scores was analyzed using appropriate regression models. Patients with NSDs located in the anterior part of the septum always have some degree of nasal obstruction, while those with posterior NSDs did not necessarily report obstruction symptoms no matter how complicated NSD they have. Regression analysis did not reveal any causal relationship between NOSE scores and CT morphology and the angle of NSD. The presence of spurs and whether they divide nasal passages have no statistically significant predictive effect on the obstruction severity. The CT morphology and the angle of the NSD could not predict severity of the nasal obstruction. Requesting CT examination just to objectively confirm nasal obstruction is not justified.
PB  - SAGE
T2  - Ear, Nose & Throat Journal
T1  - Is Computed Tomography Imaging of Deviated Nasal Septum Justified for Obstruction Confirmation?
VL  - 100
IS  - 2
SP  - 131
EP  - 136
DO  - https://doi.org/10.1177/0145561319871533
ER  - 
@article{
author = "Janović, Nataša and Janović, Aleksa and Miličić, Biljana and Đurić, Marija",
year = "2021",
abstract = "Third-party payers request objective confirmation of the nasal septum deviation (NSD) severity by computed tomography (CT) before authorizing financial support for septoplasty. Previous studies have provided contradictory results related to the link between obstruction severity and CT-measured angle of the NSD. The aim of this study was to investigate whether the diverse CT morphology of NSDs (including previously neglected types and shapes) could predict obstruction severity. The study included 225 patients with NSD. The CT morphology of the septum was analyzed using 5 different classifications of NSD that are commonly used in the clinical practice and research. The angle of NSD was also measured. Nasal obstruction was assessed by the Nasal Obstruction Symptom Evaluation (NOSE) questionnaire. A relationship between CT morphology and the angle of the NSD and NOSE scores was analyzed using appropriate regression models. Patients with NSDs located in the anterior part of the septum always have some degree of nasal obstruction, while those with posterior NSDs did not necessarily report obstruction symptoms no matter how complicated NSD they have. Regression analysis did not reveal any causal relationship between NOSE scores and CT morphology and the angle of NSD. The presence of spurs and whether they divide nasal passages have no statistically significant predictive effect on the obstruction severity. The CT morphology and the angle of the NSD could not predict severity of the nasal obstruction. Requesting CT examination just to objectively confirm nasal obstruction is not justified.",
publisher = "SAGE",
journal = "Ear, Nose & Throat Journal",
title = "Is Computed Tomography Imaging of Deviated Nasal Septum Justified for Obstruction Confirmation?",
volume = "100",
number = "2",
pages = "131-136",
doi = "https://doi.org/10.1177/0145561319871533"
}
Janović, N., Janović, A., Miličić, B.,& Đurić, M.. (2021). Is Computed Tomography Imaging of Deviated Nasal Septum Justified for Obstruction Confirmation?. in Ear, Nose & Throat Journal
SAGE., 100(2), 131-136.
https://doi.org/https://doi.org/10.1177/0145561319871533
Janović N, Janović A, Miličić B, Đurić M. Is Computed Tomography Imaging of Deviated Nasal Septum Justified for Obstruction Confirmation?. in Ear, Nose & Throat Journal. 2021;100(2):131-136.
doi:https://doi.org/10.1177/0145561319871533 .
Janović, Nataša, Janović, Aleksa, Miličić, Biljana, Đurić, Marija, "Is Computed Tomography Imaging of Deviated Nasal Septum Justified for Obstruction Confirmation?" in Ear, Nose & Throat Journal, 100, no. 2 (2021):131-136,
https://doi.org/https://doi.org/10.1177/0145561319871533 . .
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Introducing Nasal Obstruction Symptom Evaluation (NOSE) scale in clinical practice in Serbia: validation and cross-cultural adaptation

Janović, Nataša; Marić, Gorica; Dušanović, Marija; Janović, Aleksa; Pekmezović, Tatjana; Đurić, Marija

(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2020)

TY  - JOUR
AU  - Janović, Nataša
AU  - Marić, Gorica
AU  - Dušanović, Marija
AU  - Janović, Aleksa
AU  - Pekmezović, Tatjana
AU  - Đurić, Marija
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/3295
AB  - Background/Aim. The Nasal Obstruction Symptom Evaluation (NOSE) scale is widely used in clinical practice for assessment of quality of life in patients with nasal obstruction. It has been validated in several countries up to date. The aim of this study was to validate and crossculturally adapt the NOSE scale for Serbian population. Methods. The Serbian version of the NOSE scale (NOSEs) was prepared through forward and backward translation, committee review, and pretesting. Validation process was carried out on 50 patients diagnosed with the nasal septal deviation (the study group) and 50 ear, nose and throat (ENT) patients with other non-rhinological diagnosis (the control group). Results. The NOSE-s instrument demonstrated good reliability (Cronbach α coefficient 0.81). Stability and reliability of the NOSE-s questionnaire were confirmed by test-retest procedure showing no statistically significant difference in obtained responses (Goodman- Kruskal gamma coefficient 0.83). Item and total scores were significantly higher in the study group than in the control group indicating the very good inter-group discrimination (p < 0.001). Inter-item and item-total correlations were similar to the original NOSE instrument. Three months after septoplasty, a mean NOSE-s score in patients was 19.2 ± 12.8. Calculated standardized response mean of 1.7 showed high sensitivity to change. Conclusion. The Serbian version of the NOSE scale is simple, valid and reliable instrument for estimating the nasal obstruction. Therefore, it can be recommended for application in rhinological practice and research in Serbian speaking population.
AB  - Uvod/Cilj. Nasal Obstruction Symptom Evaluation (NOSE) ska-
la se koristi u kliničkoj praksi za procenu kvaliteta života bole-
snika sa nazalnom opstrukcijom. Do sada je validirana u ne-
koliko zemalja. Cilj ove studije je bio da se validira i kultural-
no adaptira NOSE skala za korišćenje u srpskoj populaciji.
Metode. Srpska verzija NOSE scale (NOSE-s) je pripremana
na sledeći način: prevodom na srpski jezik, potom povratnim
prevodom na engleski jezik, komisijskim pregledom prevoda i
pretestiranjem skale. Proces validacije sproveden je u grupi od
50 bolesnika sa postavljenom dijagnozom devijacije nosne
pregrade (studijska grupa) i među 50 bolesnika koji su se lečili
na Klinici za uho, grlo i nos, kod kojih je postavljena dijagno-
za nekog drugog ne-rinološkog problema (kontrolna grupa).
Rezultati. NOSE-s instrument je pokazao dobru pouzdanost
(Cronbach α coefficient 0.81). Stabilnost i pouzdanost NO-
SE-s upitnika su potvrđeni test-retest procedurom pokazujući
da nema statistički značajne razlike u dobijenim odgovorima
(Goodman-Kruskal gamma coefficient 0.83). Skor pojedinačnih pi-
tanja, kao i ukupan zbir su bili viši u studijskoj grupi bolesnika
nego u kontrolnoj grupi, pokazujući da postoji razlika između
grupa (p < 0.001). Međusobna veza između pojedinačnih pita-
nja i pojedinačnog pitanja i ukupnog zbira je bila sličnih vred-
nosti kao i kod originalne skale. Tri meseca nakon septoplastike
prosečan NOSE-s skor je bio 19.2 ± 12.8. Izračunata je i vred-
nost standardized response mean (1.7) koja je pokazala visoku senzi-
tivnost upitnika na promenu. Zaključak. Srpska verzija NOSE
skale je jednostavna za korišćenje, validna i pouzdana za proce-
nu nosne opstrukcije. Zbog toga je peporučujemo za upotrebu
u svakodnevnoj rinološkoj praksi kao i u budućim kliničkim is-
traživanjima u populaciji koja govori srpski jezik.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Introducing Nasal Obstruction Symptom Evaluation (NOSE) scale in clinical practice in Serbia: validation and cross-cultural adaptation
T1  - Uvođenje Nasal Obstruction Symptom Evaluation (NOSE) skale u kliničku praksu u Srbiji: validacija i kros-kulturalna adaptacija
VL  - 77
IS  - 7
SP  - 704
EP  - 709
DO  - https://doi.org/10.2298/VSP180619130J
ER  - 
@article{
author = "Janović, Nataša and Marić, Gorica and Dušanović, Marija and Janović, Aleksa and Pekmezović, Tatjana and Đurić, Marija",
year = "2020",
abstract = "Background/Aim. The Nasal Obstruction Symptom Evaluation (NOSE) scale is widely used in clinical practice for assessment of quality of life in patients with nasal obstruction. It has been validated in several countries up to date. The aim of this study was to validate and crossculturally adapt the NOSE scale for Serbian population. Methods. The Serbian version of the NOSE scale (NOSEs) was prepared through forward and backward translation, committee review, and pretesting. Validation process was carried out on 50 patients diagnosed with the nasal septal deviation (the study group) and 50 ear, nose and throat (ENT) patients with other non-rhinological diagnosis (the control group). Results. The NOSE-s instrument demonstrated good reliability (Cronbach α coefficient 0.81). Stability and reliability of the NOSE-s questionnaire were confirmed by test-retest procedure showing no statistically significant difference in obtained responses (Goodman- Kruskal gamma coefficient 0.83). Item and total scores were significantly higher in the study group than in the control group indicating the very good inter-group discrimination (p < 0.001). Inter-item and item-total correlations were similar to the original NOSE instrument. Three months after septoplasty, a mean NOSE-s score in patients was 19.2 ± 12.8. Calculated standardized response mean of 1.7 showed high sensitivity to change. Conclusion. The Serbian version of the NOSE scale is simple, valid and reliable instrument for estimating the nasal obstruction. Therefore, it can be recommended for application in rhinological practice and research in Serbian speaking population., Uvod/Cilj. Nasal Obstruction Symptom Evaluation (NOSE) ska-
la se koristi u kliničkoj praksi za procenu kvaliteta života bole-
snika sa nazalnom opstrukcijom. Do sada je validirana u ne-
koliko zemalja. Cilj ove studije je bio da se validira i kultural-
no adaptira NOSE skala za korišćenje u srpskoj populaciji.
Metode. Srpska verzija NOSE scale (NOSE-s) je pripremana
na sledeći način: prevodom na srpski jezik, potom povratnim
prevodom na engleski jezik, komisijskim pregledom prevoda i
pretestiranjem skale. Proces validacije sproveden je u grupi od
50 bolesnika sa postavljenom dijagnozom devijacije nosne
pregrade (studijska grupa) i među 50 bolesnika koji su se lečili
na Klinici za uho, grlo i nos, kod kojih je postavljena dijagno-
za nekog drugog ne-rinološkog problema (kontrolna grupa).
Rezultati. NOSE-s instrument je pokazao dobru pouzdanost
(Cronbach α coefficient 0.81). Stabilnost i pouzdanost NO-
SE-s upitnika su potvrđeni test-retest procedurom pokazujući
da nema statistički značajne razlike u dobijenim odgovorima
(Goodman-Kruskal gamma coefficient 0.83). Skor pojedinačnih pi-
tanja, kao i ukupan zbir su bili viši u studijskoj grupi bolesnika
nego u kontrolnoj grupi, pokazujući da postoji razlika između
grupa (p < 0.001). Međusobna veza između pojedinačnih pita-
nja i pojedinačnog pitanja i ukupnog zbira je bila sličnih vred-
nosti kao i kod originalne skale. Tri meseca nakon septoplastike
prosečan NOSE-s skor je bio 19.2 ± 12.8. Izračunata je i vred-
nost standardized response mean (1.7) koja je pokazala visoku senzi-
tivnost upitnika na promenu. Zaključak. Srpska verzija NOSE
skale je jednostavna za korišćenje, validna i pouzdana za proce-
nu nosne opstrukcije. Zbog toga je peporučujemo za upotrebu
u svakodnevnoj rinološkoj praksi kao i u budućim kliničkim is-
traživanjima u populaciji koja govori srpski jezik.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Introducing Nasal Obstruction Symptom Evaluation (NOSE) scale in clinical practice in Serbia: validation and cross-cultural adaptation, Uvođenje Nasal Obstruction Symptom Evaluation (NOSE) skale u kliničku praksu u Srbiji: validacija i kros-kulturalna adaptacija",
volume = "77",
number = "7",
pages = "704-709",
doi = "https://doi.org/10.2298/VSP180619130J"
}
Janović, N., Marić, G., Dušanović, M., Janović, A., Pekmezović, T.,& Đurić, M.. (2020). Introducing Nasal Obstruction Symptom Evaluation (NOSE) scale in clinical practice in Serbia: validation and cross-cultural adaptation. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 77(7), 704-709.
https://doi.org/https://doi.org/10.2298/VSP180619130J
Janović N, Marić G, Dušanović M, Janović A, Pekmezović T, Đurić M. Introducing Nasal Obstruction Symptom Evaluation (NOSE) scale in clinical practice in Serbia: validation and cross-cultural adaptation. in Vojnosanitetski pregled. 2020;77(7):704-709.
doi:https://doi.org/10.2298/VSP180619130J .
Janović, Nataša, Marić, Gorica, Dušanović, Marija, Janović, Aleksa, Pekmezović, Tatjana, Đurić, Marija, "Introducing Nasal Obstruction Symptom Evaluation (NOSE) scale in clinical practice in Serbia: validation and cross-cultural adaptation" in Vojnosanitetski pregled, 77, no. 7 (2020):704-709,
https://doi.org/https://doi.org/10.2298/VSP180619130J . .
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