TY  - JOUR
AU  - Bracanović, Đurđa
AU  - Đurić, Marija
AU  - Sopta, Jelena
AU  - Bracanović, Miloš
AU  - Đonić, Danijela
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2505
AB  - Hyperostosis frontalis interna (HFI) presents irregular thickening of the frontal bone. Even though HFI is frequently seen during routine radiological imaging, it usually remains unrecorded owing to a common belief that it just represents an incidental finding or anatomical variant. Recent studies implied that HFI may be clinically relevant. Etiology of HFI is still debated, while presumptions are mainly based on altered sex steroids impact on skull bone growth. Some authors implied that frontal bone might be particularly affected by this condition due to specificity of its underlying dura. In this paper we present a 27-years old female patient with a treatment resistant headache. Head CT showed massive, irregular bony mass, with lobulated contours arising from the right frontal bone, but did not cross the fronto-parietal suture, spearing the superior sagittal sinus and skull midline. After surgery, histopathological analysis of the frontal bone sample in our patient showed thickening pattern similar to those described in micro-CT studies of HFI. Furthermore, in an attempt to test speculation of the possible role of estrogen in pathogenesis of HFI, we investigated the expression of a-estrogen receptors on dura of the frontal region. These analyses confirmed nuclear expression of estrogen on frontal region dural tissue, supporting previous speculation of the development mechanisms of HFI and contributing to a better understanding of this common condition of the frontal bone. Additionally, the presence of HFI may result in severe symptomatology, which could be misinterpreted and related to other disorders if HFI is not radiologicaly recognized and reported.
PB  - Elsevier Gmbh, Munich
T2  - Homo - Journal of Comparative Human Biology
T1  - Radiological evaluation of Hyperostosis frontalis interna: is it of clinical importance?
VL  - 71
IS  - 2
SP  - 155
EP  - 160
DO  - 10.1127/homo/2020/1134
ER  - 

@article{
author = "Bracanović, Đurđa and Đurić, Marija and Sopta, Jelena and Bracanović, Miloš and Đonić, Danijela",
year = "2020",
abstract = "Hyperostosis frontalis interna (HFI) presents irregular thickening of the frontal bone. Even though HFI is frequently seen during routine radiological imaging, it usually remains unrecorded owing to a common belief that it just represents an incidental finding or anatomical variant. Recent studies implied that HFI may be clinically relevant. Etiology of HFI is still debated, while presumptions are mainly based on altered sex steroids impact on skull bone growth. Some authors implied that frontal bone might be particularly affected by this condition due to specificity of its underlying dura. In this paper we present a 27-years old female patient with a treatment resistant headache. Head CT showed massive, irregular bony mass, with lobulated contours arising from the right frontal bone, but did not cross the fronto-parietal suture, spearing the superior sagittal sinus and skull midline. After surgery, histopathological analysis of the frontal bone sample in our patient showed thickening pattern similar to those described in micro-CT studies of HFI. Furthermore, in an attempt to test speculation of the possible role of estrogen in pathogenesis of HFI, we investigated the expression of a-estrogen receptors on dura of the frontal region. These analyses confirmed nuclear expression of estrogen on frontal region dural tissue, supporting previous speculation of the development mechanisms of HFI and contributing to a better understanding of this common condition of the frontal bone. Additionally, the presence of HFI may result in severe symptomatology, which could be misinterpreted and related to other disorders if HFI is not radiologicaly recognized and reported.",
publisher = "Elsevier Gmbh, Munich",
journal = "Homo - Journal of Comparative Human Biology",
title = "Radiological evaluation of Hyperostosis frontalis interna: is it of clinical importance?",
volume = "71",
number = "2",
pages = "155-160",
doi = "10.1127/homo/2020/1134"
}

Bracanović, Đ., Đurić, M., Sopta, J., Bracanović, M.,& Đonić, D.. (2020). Radiological evaluation of Hyperostosis frontalis interna: is it of clinical importance?. in Homo - Journal of Comparative Human Biology
Elsevier Gmbh, Munich., 71(2), 155-160.
https://doi.org/10.1127/homo/2020/1134

Bracanović Đ, Đurić M, Sopta J, Bracanović M, Đonić D. Radiological evaluation of Hyperostosis frontalis interna: is it of clinical importance?. in Homo - Journal of Comparative Human Biology. 2020;71(2):155-160.
doi:10.1127/homo/2020/1134 .

Bracanović, Đurđa, Đurić, Marija, Sopta, Jelena, Bracanović, Miloš, Đonić, Danijela, "Radiological evaluation of Hyperostosis frontalis interna: is it of clinical importance?" in Homo - Journal of Comparative Human Biology, 71, no. 2 (2020):155-160,
https://doi.org/10.1127/homo/2020/1134 . .

TY  - JOUR
AU  - Jokanović, Vukoman
AU  - Čolović, Božana
AU  - Marković, Dejan
AU  - Petrović, Milan
AU  - Soldatović, Ivan
AU  - Antonijević, Đorđe
AU  - Milosavljević, Petar
AU  - Sjerobabin, Nikola
AU  - Sopta, Jelena
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2187
AB  - This study examined the potential of a new porous calcium hydroxyapatite scaffold covered with poly (lactide-co-glycolide) (PLGA) as a bone substitute, identifying its advantages over Geistlich Bio-Oss (R), considered the gold standard, in in vivo biofunctionality investigations. Structural and morphological properties of the new scaffold were analyzed by scanning electron and atomic force microscopy. The biofunctionality assays were performed on New Zealand white rabbits using new scaffold for filling full-thickness defects of critical size. The evaluated parameters were: the presence of macrophages, giant cells, monoocytes, plasma cells, granulocytes, neo-angiogenesis, fibroplasia, and the percentage of mineralization. Parallel biofunctionality assays were performed using Geistlich Bio-Oss (R). The appearance of bone defects 12 weeks after the new scaffold implantation showed the presence of a small number of typical immune response cells. Furthermore, significantly reduced number of capillary buds, low intensity of fibroplasia and high degree of mineralization in a lamellar pattern indicated that the inflammation process has been almost completely overcome and that the new bone formed was in the final phase of remodeling. All biofunctionality assays proved the new scaffold's suitability as a bone substitute for applications in maxillofacial surgery. It showed numerous biological advantages over Geistlich Bio-Oss (R) which was reflected mainly as a lower number of giant cells surrounding implanted material and higher degree of mineralization in new formed bone.
PB  - Walter De Gruyter Gmbh, Berlin
T2  - Biomedical Engineering - Biomedizinische Technik
T1  - Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation
VL  - 62
IS  - 3
SP  - 295
EP  - 306
DO  - 10.1515/bmt-2015-0164
ER  - 

@article{
author = "Jokanović, Vukoman and Čolović, Božana and Marković, Dejan and Petrović, Milan and Soldatović, Ivan and Antonijević, Đorđe and Milosavljević, Petar and Sjerobabin, Nikola and Sopta, Jelena",
year = "2017",
abstract = "This study examined the potential of a new porous calcium hydroxyapatite scaffold covered with poly (lactide-co-glycolide) (PLGA) as a bone substitute, identifying its advantages over Geistlich Bio-Oss (R), considered the gold standard, in in vivo biofunctionality investigations. Structural and morphological properties of the new scaffold were analyzed by scanning electron and atomic force microscopy. The biofunctionality assays were performed on New Zealand white rabbits using new scaffold for filling full-thickness defects of critical size. The evaluated parameters were: the presence of macrophages, giant cells, monoocytes, plasma cells, granulocytes, neo-angiogenesis, fibroplasia, and the percentage of mineralization. Parallel biofunctionality assays were performed using Geistlich Bio-Oss (R). The appearance of bone defects 12 weeks after the new scaffold implantation showed the presence of a small number of typical immune response cells. Furthermore, significantly reduced number of capillary buds, low intensity of fibroplasia and high degree of mineralization in a lamellar pattern indicated that the inflammation process has been almost completely overcome and that the new bone formed was in the final phase of remodeling. All biofunctionality assays proved the new scaffold's suitability as a bone substitute for applications in maxillofacial surgery. It showed numerous biological advantages over Geistlich Bio-Oss (R) which was reflected mainly as a lower number of giant cells surrounding implanted material and higher degree of mineralization in new formed bone.",
publisher = "Walter De Gruyter Gmbh, Berlin",
journal = "Biomedical Engineering - Biomedizinische Technik",
title = "Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation",
volume = "62",
number = "3",
pages = "295-306",
doi = "10.1515/bmt-2015-0164"
}

Jokanović, V., Čolović, B., Marković, D., Petrović, M., Soldatović, I., Antonijević, Đ., Milosavljević, P., Sjerobabin, N.,& Sopta, J.. (2017). Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation. in Biomedical Engineering - Biomedizinische Technik
Walter De Gruyter Gmbh, Berlin., 62(3), 295-306.
https://doi.org/10.1515/bmt-2015-0164

Jokanović V, Čolović B, Marković D, Petrović M, Soldatović I, Antonijević Đ, Milosavljević P, Sjerobabin N, Sopta J. Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation. in Biomedical Engineering - Biomedizinische Technik. 2017;62(3):295-306.
doi:10.1515/bmt-2015-0164 .

Jokanović, Vukoman, Čolović, Božana, Marković, Dejan, Petrović, Milan, Soldatović, Ivan, Antonijević, Đorđe, Milosavljević, Petar, Sjerobabin, Nikola, Sopta, Jelena, "Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation" in Biomedical Engineering - Biomedizinische Technik, 62, no. 3 (2017):295-306,
https://doi.org/10.1515/bmt-2015-0164 . .

TY  - JOUR
AU  - Jokanović, Vukoman
AU  - Čolović, Božana
AU  - Marković, Dejan
AU  - Petrović, Milan
AU  - Jokanović, Milan
AU  - Milosavljević, Petar
AU  - Sopta, Jelena
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2168
AB  - A synthetic bone substitute based on calcium hydroxyapatite (CHA) and poly(lactic-co-glycolic) acid (PLGA), described in this paper, was synthesized to fulfill specific requirements like biodegradability, satisfying mechanical properties, optimal porosity and nanotopology, osteoinductive and osteoconductive properties, and so forth. Structural and morphological properties of the new scaffold were analyzed by micro computed tomography and scanning electron microscopy, while its physicochemical properties were investigated by X-ray diffraction and infrared spectroscopy. In vivo biological investigations of the synthesized scaffold were conducted over the cutaneous irritation and biofunctionality assays on rabbits and the test of acute systemic toxicity on mice. The results showed that the scaffold is not irritant and that it does not exhibit any symptoms of acute toxicity. Biofunctionality assays which include evaluation of the presence of various cells of immune response, the presence of neoangiogenesis, percentage of mineralization of newly formed bone, and fibroplasia in the tissue indicated that the new scaffold is suitable for the application in maxillofacial and dental surgery as a bone substitute. Also, it showed significant advantages over commercial product Geistlich Bio-Oss(R) from the aspect of some parameters of immunological response.
PB  - Hindawi Ltd, London
T2  - Journal of Nanomaterials
T1  - In Vivo Investigation of ALBO-OS Scaffold Based on Hydroxyapatite and PLGA
VL  - 2016
DO  - 10.1155/2016/3948768
ER  - 

@article{
author = "Jokanović, Vukoman and Čolović, Božana and Marković, Dejan and Petrović, Milan and Jokanović, Milan and Milosavljević, Petar and Sopta, Jelena",
year = "2016",
abstract = "A synthetic bone substitute based on calcium hydroxyapatite (CHA) and poly(lactic-co-glycolic) acid (PLGA), described in this paper, was synthesized to fulfill specific requirements like biodegradability, satisfying mechanical properties, optimal porosity and nanotopology, osteoinductive and osteoconductive properties, and so forth. Structural and morphological properties of the new scaffold were analyzed by micro computed tomography and scanning electron microscopy, while its physicochemical properties were investigated by X-ray diffraction and infrared spectroscopy. In vivo biological investigations of the synthesized scaffold were conducted over the cutaneous irritation and biofunctionality assays on rabbits and the test of acute systemic toxicity on mice. The results showed that the scaffold is not irritant and that it does not exhibit any symptoms of acute toxicity. Biofunctionality assays which include evaluation of the presence of various cells of immune response, the presence of neoangiogenesis, percentage of mineralization of newly formed bone, and fibroplasia in the tissue indicated that the new scaffold is suitable for the application in maxillofacial and dental surgery as a bone substitute. Also, it showed significant advantages over commercial product Geistlich Bio-Oss(R) from the aspect of some parameters of immunological response.",
publisher = "Hindawi Ltd, London",
journal = "Journal of Nanomaterials",
title = "In Vivo Investigation of ALBO-OS Scaffold Based on Hydroxyapatite and PLGA",
volume = "2016",
doi = "10.1155/2016/3948768"
}

Jokanović, V., Čolović, B., Marković, D., Petrović, M., Jokanović, M., Milosavljević, P.,& Sopta, J.. (2016). In Vivo Investigation of ALBO-OS Scaffold Based on Hydroxyapatite and PLGA. in Journal of Nanomaterials
Hindawi Ltd, London., 2016.
https://doi.org/10.1155/2016/3948768

Jokanović V, Čolović B, Marković D, Petrović M, Jokanović M, Milosavljević P, Sopta J. In Vivo Investigation of ALBO-OS Scaffold Based on Hydroxyapatite and PLGA. in Journal of Nanomaterials. 2016;2016.
doi:10.1155/2016/3948768 .

Jokanović, Vukoman, Čolović, Božana, Marković, Dejan, Petrović, Milan, Jokanović, Milan, Milosavljević, Petar, Sopta, Jelena, "In Vivo Investigation of ALBO-OS Scaffold Based on Hydroxyapatite and PLGA" in Journal of Nanomaterials, 2016 (2016),
https://doi.org/10.1155/2016/3948768 . .

TY  - JOUR
AU  - Janović, Aleksa
AU  - Milovanović, Petar
AU  - Sopta, Jelena
AU  - Rakočević, Zoran
AU  - Filipović, Vojislav
AU  - Nenezić, Dragoslav
AU  - Đurić, Marija
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/3296
AB  - Endocranial bone lesions have attracted intensive scientific debate on their aetiology. In recent literature, the lesions were almost exclusively interpreted as of infectious origin. In this paper, we give new insight into the aetiology of endocranial lesions, distinguishing the lesions of vascular origin from those caused by tuberculosis or other conditions. The analysis is based on a rare case of a young female individual who displayed multiple endocranial lesions with ‘serpens endocrania symmetrica’ morphology. The lesions were associated with an uncommon branching pattern of the middle meningeal artery and marked side differences in teeth pathology. Postcranial skeleton showed signs of the left upper limb weakness. The macroscopic finding of the endocranial lesions along with the skeletal evidence of neurological damage, together with characteristic radiological and histological features, can lead to diagnosis of arteriovenous malformations. This study aims to improve understanding of the aetiology of endocranial bone lesions.
PB  - Wiley-Blackwell, Hoboken
T2  - International Journal of Osteoarchaeology
T1  - Intracranial Arteriovenous Malformations as a Possible Cause of Endocranial Bone Lesions and Associated Neurological Disorder
VL  - 25
IS  - 1
SP  - 88
EP  - 97
DO  - https://doi.org/10.1002/oa.2266
ER  - 

@article{
author = "Janović, Aleksa and Milovanović, Petar and Sopta, Jelena and Rakočević, Zoran and Filipović, Vojislav and Nenezić, Dragoslav and Đurić, Marija",
year = "2015",
abstract = "Endocranial bone lesions have attracted intensive scientific debate on their aetiology. In recent literature, the lesions were almost exclusively interpreted as of infectious origin. In this paper, we give new insight into the aetiology of endocranial lesions, distinguishing the lesions of vascular origin from those caused by tuberculosis or other conditions. The analysis is based on a rare case of a young female individual who displayed multiple endocranial lesions with ‘serpens endocrania symmetrica’ morphology. The lesions were associated with an uncommon branching pattern of the middle meningeal artery and marked side differences in teeth pathology. Postcranial skeleton showed signs of the left upper limb weakness. The macroscopic finding of the endocranial lesions along with the skeletal evidence of neurological damage, together with characteristic radiological and histological features, can lead to diagnosis of arteriovenous malformations. This study aims to improve understanding of the aetiology of endocranial bone lesions.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "International Journal of Osteoarchaeology",
title = "Intracranial Arteriovenous Malformations as a Possible Cause of Endocranial Bone Lesions and Associated Neurological Disorder",
volume = "25",
number = "1",
pages = "88-97",
doi = "https://doi.org/10.1002/oa.2266"
}

Janović, A., Milovanović, P., Sopta, J., Rakočević, Z., Filipović, V., Nenezić, D.,& Đurić, M.. (2015). Intracranial Arteriovenous Malformations as a Possible Cause of Endocranial Bone Lesions and Associated Neurological Disorder. in International Journal of Osteoarchaeology
Wiley-Blackwell, Hoboken., 25(1), 88-97.
https://doi.org/https://doi.org/10.1002/oa.2266

Janović A, Milovanović P, Sopta J, Rakočević Z, Filipović V, Nenezić D, Đurić M. Intracranial Arteriovenous Malformations as a Possible Cause of Endocranial Bone Lesions and Associated Neurological Disorder. in International Journal of Osteoarchaeology. 2015;25(1):88-97.
doi:https://doi.org/10.1002/oa.2266 .

Janović, Aleksa, Milovanović, Petar, Sopta, Jelena, Rakočević, Zoran, Filipović, Vojislav, Nenezić, Dragoslav, Đurić, Marija, "Intracranial Arteriovenous Malformations as a Possible Cause of Endocranial Bone Lesions and Associated Neurological Disorder" in International Journal of Osteoarchaeology, 25, no. 1 (2015):88-97,
https://doi.org/https://doi.org/10.1002/oa.2266 . .

TY  - JOUR
AU  - Bracanović, Đurđa
AU  - Đurić, Marija
AU  - Sopta, Jelena
AU  - Đonić, Danijela
AU  - Lujić, Nenad
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1831
AB  - Although Serbia is recognized as an endemic country for echinococcosis, no information about precise incidence in humans has been available. The aim of this study was to investigate the skeletal manifestations of hydatid disease in Serbia. This retrospective study was conducted by reviewing the medical database of Institute for Pathology (Faculty of Medicine in Belgrade), a reference institution for bone pathology in Serbia. We reported a total of 41 patients with bone cystic echinococcosis (CE) during the study period. The mean age of 41 patients was 40.9 +/- 18.8 years. In 39% of patients, the fracture line was the only visible radiological sign, followed by cyst and tumefaction. The spine was the most commonly involved skeletal site (55.8%), followed by the femur (18.6%), pelvis (13.9%), humerus (7.0%), rib (2.3%), and tibia (2.3%). Pain was the symptom in 41.5% of patients, while some patients demonstrated complications such as paraplegia (22.0%), pathologic fracture (48.8%), and scoliosis (9.8%). The pathological fracture most frequently affected the spine (75.0%) followed by the femur (20.0%) and tibia (5.0%). However, 19.5% of patients didn't develop any complication or symptom. In this study, we showed that bone CE is not uncommon in Serbian population. As reported in the literature, therapy of bone CE is controversial and its results are poor. In order to improve the therapy outcome, early diagnosis, before symptoms and complications occur, can be contributive.
PB  - Korean Soc Parasitology, Seoul Natl Univ Coll Medi, Seoul
T2  - Korean Journal of Parasitology
T1  - Skeletal Manifestations of Hydatid Disease in Serbia: Demographic Distribution, Site Involvement, Radiological Findings, and Complications
VL  - 51
IS  - 4
SP  - 453
EP  - 459
DO  - 10.3347/kjp.2013.51.4.453
ER  - 

@article{
author = "Bracanović, Đurđa and Đurić, Marija and Sopta, Jelena and Đonić, Danijela and Lujić, Nenad",
year = "2013",
abstract = "Although Serbia is recognized as an endemic country for echinococcosis, no information about precise incidence in humans has been available. The aim of this study was to investigate the skeletal manifestations of hydatid disease in Serbia. This retrospective study was conducted by reviewing the medical database of Institute for Pathology (Faculty of Medicine in Belgrade), a reference institution for bone pathology in Serbia. We reported a total of 41 patients with bone cystic echinococcosis (CE) during the study period. The mean age of 41 patients was 40.9 +/- 18.8 years. In 39% of patients, the fracture line was the only visible radiological sign, followed by cyst and tumefaction. The spine was the most commonly involved skeletal site (55.8%), followed by the femur (18.6%), pelvis (13.9%), humerus (7.0%), rib (2.3%), and tibia (2.3%). Pain was the symptom in 41.5% of patients, while some patients demonstrated complications such as paraplegia (22.0%), pathologic fracture (48.8%), and scoliosis (9.8%). The pathological fracture most frequently affected the spine (75.0%) followed by the femur (20.0%) and tibia (5.0%). However, 19.5% of patients didn't develop any complication or symptom. In this study, we showed that bone CE is not uncommon in Serbian population. As reported in the literature, therapy of bone CE is controversial and its results are poor. In order to improve the therapy outcome, early diagnosis, before symptoms and complications occur, can be contributive.",
publisher = "Korean Soc Parasitology, Seoul Natl Univ Coll Medi, Seoul",
journal = "Korean Journal of Parasitology",
title = "Skeletal Manifestations of Hydatid Disease in Serbia: Demographic Distribution, Site Involvement, Radiological Findings, and Complications",
volume = "51",
number = "4",
pages = "453-459",
doi = "10.3347/kjp.2013.51.4.453"
}

Bracanović, Đ., Đurić, M., Sopta, J., Đonić, D.,& Lujić, N.. (2013). Skeletal Manifestations of Hydatid Disease in Serbia: Demographic Distribution, Site Involvement, Radiological Findings, and Complications. in Korean Journal of Parasitology
Korean Soc Parasitology, Seoul Natl Univ Coll Medi, Seoul., 51(4), 453-459.
https://doi.org/10.3347/kjp.2013.51.4.453

Bracanović Đ, Đurić M, Sopta J, Đonić D, Lujić N. Skeletal Manifestations of Hydatid Disease in Serbia: Demographic Distribution, Site Involvement, Radiological Findings, and Complications. in Korean Journal of Parasitology. 2013;51(4):453-459.
doi:10.3347/kjp.2013.51.4.453 .

Bracanović, Đurđa, Đurić, Marija, Sopta, Jelena, Đonić, Danijela, Lujić, Nenad, "Skeletal Manifestations of Hydatid Disease in Serbia: Demographic Distribution, Site Involvement, Radiological Findings, and Complications" in Korean Journal of Parasitology, 51, no. 4 (2013):453-459,
https://doi.org/10.3347/kjp.2013.51.4.453 . .

TY  - JOUR
AU  - Sopta, Jelena
AU  - Dražić, Radojica
AU  - Tulić, Goran
AU  - Mijucić, Vesna
AU  - Tepavčević, Zvezdana
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1624
AB  - Cemento-ossifying fibroma (COF) belongs to the group of bone-related lesions of the oral cavity. The aim of this study was refine its histologic features and to correlate histopathological picture and clinical behavior of the tumor. The quantity of bone spherules, their cellularity, the existence of hemorrhage, inflammation, and endochondral ossification in the stroma of the tumor were analyzed and correlated with patients main symptoms of ten patients with COF. All patients had swelling that lasted between 3 and 20 months (mean 10.4 months). Other clinical symptoms were facial asymmetry, eye bulb protrusion, and teeth displacement. The evolution of the tumor was longer in the mandible (12.3 months) than in maxilla (9.5 months). The main histomorphological diagnostic criterion for COF was psammoma-like structures. In lesions with longer case history, the number of "psammomatoid" bodies was greater. In lesions with shorter course of the disease, their number was lower and stromal hemorrhage and inflammation were presented. One patient had secondary superposition of aneurysmal bone cyst in the prime COF of mandible. Histological appearance of COF may be influenced by the tumor evolution. A siginificant correlation between the clinical course of the disease and histological parameters has been certified.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Cemento-ossifying fibroma of jaws-correlation of clinical and pathological findings
VL  - 15
IS  - 2
SP  - 201
EP  - 207
DO  - 10.1007/s00784-010-0381-2
ER  - 

@article{
author = "Sopta, Jelena and Dražić, Radojica and Tulić, Goran and Mijucić, Vesna and Tepavčević, Zvezdana",
year = "2011",
abstract = "Cemento-ossifying fibroma (COF) belongs to the group of bone-related lesions of the oral cavity. The aim of this study was refine its histologic features and to correlate histopathological picture and clinical behavior of the tumor. The quantity of bone spherules, their cellularity, the existence of hemorrhage, inflammation, and endochondral ossification in the stroma of the tumor were analyzed and correlated with patients main symptoms of ten patients with COF. All patients had swelling that lasted between 3 and 20 months (mean 10.4 months). Other clinical symptoms were facial asymmetry, eye bulb protrusion, and teeth displacement. The evolution of the tumor was longer in the mandible (12.3 months) than in maxilla (9.5 months). The main histomorphological diagnostic criterion for COF was psammoma-like structures. In lesions with longer case history, the number of "psammomatoid" bodies was greater. In lesions with shorter course of the disease, their number was lower and stromal hemorrhage and inflammation were presented. One patient had secondary superposition of aneurysmal bone cyst in the prime COF of mandible. Histological appearance of COF may be influenced by the tumor evolution. A siginificant correlation between the clinical course of the disease and histological parameters has been certified.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Cemento-ossifying fibroma of jaws-correlation of clinical and pathological findings",
volume = "15",
number = "2",
pages = "201-207",
doi = "10.1007/s00784-010-0381-2"
}

Sopta, J., Dražić, R., Tulić, G., Mijucić, V.,& Tepavčević, Z.. (2011). Cemento-ossifying fibroma of jaws-correlation of clinical and pathological findings. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 15(2), 201-207.
https://doi.org/10.1007/s00784-010-0381-2

Sopta J, Dražić R, Tulić G, Mijucić V, Tepavčević Z. Cemento-ossifying fibroma of jaws-correlation of clinical and pathological findings. in Clinical Oral Investigations. 2011;15(2):201-207.
doi:10.1007/s00784-010-0381-2 .

Sopta, Jelena, Dražić, Radojica, Tulić, Goran, Mijucić, Vesna, Tepavčević, Zvezdana, "Cemento-ossifying fibroma of jaws-correlation of clinical and pathological findings" in Clinical Oral Investigations, 15, no. 2 (2011):201-207,
https://doi.org/10.1007/s00784-010-0381-2 . .

TY  - JOUR
AU  - Dražić, Radojica
AU  - Sopta, Jelena
AU  - Minić, Arsa J.
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1521
AB  - Objective: The aim of this study was to qualitatively and semi-quantitatively analyze mast cells in periapical lesions. Materials and methods: Biopsy specimens of 96 periapical lesions were stained with hematoxylin-eosin, histochemical Giemsa and immunohistochemical CD 117 (C kit) antibody. Mast cell count below 100 mast cells on 1000 fields of high power magnification was noted as 'negative', 101-400 as 'mild', 401-800 cells as 'moderate', and over 800 cells as 'severe'. Results: Mast cells are found in 68 (70.8%) lesions. The presence of mast cells was greater in cysts than in granulomas (P  lt  0.0028). There was no difference in semi-quantitative expression of CD 117 in granulomas and cysts (P > 0.05). Mast cells were placed in both: inflammatory infiltrate and in fibroblastic areas of periapical lesions, and their presence was most frequently mild to moderate. Conclusions: The findings of present study could suggest a role of mast cells in regulation of cellular immune mechanisms in periapical lesions, balancing between alterative and reparatory processes in inflamed periapical tissue.
PB  - Wiley-Blackwell Publishing, Inc, Malden
T2  - Journal of Oral Pathology & Medicine
T1  - Mast cells in periapical lesions: potential role in their pathogenesis
VL  - 39
IS  - 3
SP  - 257
EP  - 262
DO  - 10.1111/j.1600-0714.2009.00870.x
ER  - 

@article{
author = "Dražić, Radojica and Sopta, Jelena and Minić, Arsa J.",
year = "2010",
abstract = "Objective: The aim of this study was to qualitatively and semi-quantitatively analyze mast cells in periapical lesions. Materials and methods: Biopsy specimens of 96 periapical lesions were stained with hematoxylin-eosin, histochemical Giemsa and immunohistochemical CD 117 (C kit) antibody. Mast cell count below 100 mast cells on 1000 fields of high power magnification was noted as 'negative', 101-400 as 'mild', 401-800 cells as 'moderate', and over 800 cells as 'severe'. Results: Mast cells are found in 68 (70.8%) lesions. The presence of mast cells was greater in cysts than in granulomas (P  lt  0.0028). There was no difference in semi-quantitative expression of CD 117 in granulomas and cysts (P > 0.05). Mast cells were placed in both: inflammatory infiltrate and in fibroblastic areas of periapical lesions, and their presence was most frequently mild to moderate. Conclusions: The findings of present study could suggest a role of mast cells in regulation of cellular immune mechanisms in periapical lesions, balancing between alterative and reparatory processes in inflamed periapical tissue.",
publisher = "Wiley-Blackwell Publishing, Inc, Malden",
journal = "Journal of Oral Pathology & Medicine",
title = "Mast cells in periapical lesions: potential role in their pathogenesis",
volume = "39",
number = "3",
pages = "257-262",
doi = "10.1111/j.1600-0714.2009.00870.x"
}

Dražić, R., Sopta, J.,& Minić, A. J.. (2010). Mast cells in periapical lesions: potential role in their pathogenesis. in Journal of Oral Pathology & Medicine
Wiley-Blackwell Publishing, Inc, Malden., 39(3), 257-262.
https://doi.org/10.1111/j.1600-0714.2009.00870.x

Dražić R, Sopta J, Minić AJ. Mast cells in periapical lesions: potential role in their pathogenesis. in Journal of Oral Pathology & Medicine. 2010;39(3):257-262.
doi:10.1111/j.1600-0714.2009.00870.x .

Dražić, Radojica, Sopta, Jelena, Minić, Arsa J., "Mast cells in periapical lesions: potential role in their pathogenesis" in Journal of Oral Pathology & Medicine, 39, no. 3 (2010):257-262,
https://doi.org/10.1111/j.1600-0714.2009.00870.x . .