TY  - JOUR
AU  - Jokanović, Vukoman
AU  - Čolović, Božana
AU  - Ćetenović, Bojana
AU  - Živković, Slavoljub
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2427
AB  - Various magnetron-sputtering methods for surface modification of shape memory alloys (SMA) are described in this paper. These methods belong to the most effective methods, which enable mechanical reinforcing of the SMA, showing numerous advantages over conventional methods of electro-polishing. In addition, surface modified SMA, particularly with equiatomic TiNi coatings, is crucial for further development of various endodontic instruments; wires and brackets used for orthodontic teeth movements. Active coatings with bactericide properties and coatings that can be used as barrier for release of toxic Ni ions from the bulk body of SMA obtained by various magnetron-sputtering methods can be successfully combined. Therefore, the review of these methods is given in this paper, with their main characteristics and drawbacks. Magnetron sputtering deposition involves surface modification of SMA in a single-layer, multilayer, graded layers, and nanocomposite thin coatings for obtaining systems with superior "functional" characteristics. These are hardness, scratch, abrasion, and erosion resistance, improved adhesion to various technologically important substrate materials such as polymers, hydrophobicity or hydrophilicity, long-term chemical, thermal, and environmental stability, gas and vapor impermeability, and others. This paper is critical review of the advances in the development of magnetron sputtering modified SMA products in dentistry, with in advance predictable physicochemical, structural and antimicrobial properties.
AB  - U ovom radu su opisane različite metode magnetronskog raspršivanja za površinsku modifikaciju memorijskih legura (shape memory alloys - SMA). Ove metode spadaju u najefikasnije metode koje omogućavaju mehaničko ojačavanje SMA, pokazujući brojne prednosti u odnosu na konvencionalne metode elektropoliranja, koje su najčešće korišćene u savremenoj ortodontskoj i endodontskoj praksi. Pored toga, površinski modifikovane SMA, posebno sa ekviatomskim Ti i Ni udelima unutar prevlake, presudne su za dalji razvoj različitih endodontskih instrumenata, žica i konzola koje se koriste za ortodontska pomeranja zuba. Aktivne prevlake sa baktericidnim svojstvima i prevlake koje služe kao barijere protiv otpuštanja toksičnih Ni jona iz SMA unutar organizma mogu biti dobijene različitim metodama magnetronskog raspršivanja, pri čemu se različite varijante ove metode mogu uspešno kombinovati. Zbog svega toga u ovom radu je dat pregled ovih metoda, sa njihovim glavnim karakteristikama i nedostacima. Magnetronsko nanošenje raspršivanjem uključuje površinsku modifikaciju SMA u jednoslojnim, višeslojnim, gradiranim slojevima i nanokompozitne tanke prevlake za dobijanje sistema sa superiornim "funkcionalnim" karakteristikama, kao što su vrlo visoka tvrdoća, otpornost na habanje, abraziju i eroziju, poboljšano prijanjanje na različite tehnološki važne supstratne materijale kao što su polimeri, hidrofobnost ili hidrofilnost, dugotrajna hemijska, termička i ekološka stabilnost, nepropusnost gasa i para i drugi. Ovaj rad predstavlja neku vrstu kritičkog pregleda napretka u razvoju magnetronskog raspršivanja modifikovanih SMA proizvoda u stomatologiji, sa unapred predvidljivim fizičko-hemijskim, strukturnim i antimikrobnim osobinama.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Magnetron sputtering methods for surface modification of shape memory alloys for applications in orthodontics and endodontics
T1  - Metode magnetronskog raspršivanja za površinsku modifikaciju memorijskih legura za primenu u ortodonciji i endodonciji
VL  - 66
IS  - 2
SP  - 87
EP  - 96
DO  - 10.2478/sdj-2019-0010
ER  - 

@article{
author = "Jokanović, Vukoman and Čolović, Božana and Ćetenović, Bojana and Živković, Slavoljub",
year = "2019",
abstract = "Various magnetron-sputtering methods for surface modification of shape memory alloys (SMA) are described in this paper. These methods belong to the most effective methods, which enable mechanical reinforcing of the SMA, showing numerous advantages over conventional methods of electro-polishing. In addition, surface modified SMA, particularly with equiatomic TiNi coatings, is crucial for further development of various endodontic instruments; wires and brackets used for orthodontic teeth movements. Active coatings with bactericide properties and coatings that can be used as barrier for release of toxic Ni ions from the bulk body of SMA obtained by various magnetron-sputtering methods can be successfully combined. Therefore, the review of these methods is given in this paper, with their main characteristics and drawbacks. Magnetron sputtering deposition involves surface modification of SMA in a single-layer, multilayer, graded layers, and nanocomposite thin coatings for obtaining systems with superior "functional" characteristics. These are hardness, scratch, abrasion, and erosion resistance, improved adhesion to various technologically important substrate materials such as polymers, hydrophobicity or hydrophilicity, long-term chemical, thermal, and environmental stability, gas and vapor impermeability, and others. This paper is critical review of the advances in the development of magnetron sputtering modified SMA products in dentistry, with in advance predictable physicochemical, structural and antimicrobial properties., U ovom radu su opisane različite metode magnetronskog raspršivanja za površinsku modifikaciju memorijskih legura (shape memory alloys - SMA). Ove metode spadaju u najefikasnije metode koje omogućavaju mehaničko ojačavanje SMA, pokazujući brojne prednosti u odnosu na konvencionalne metode elektropoliranja, koje su najčešće korišćene u savremenoj ortodontskoj i endodontskoj praksi. Pored toga, površinski modifikovane SMA, posebno sa ekviatomskim Ti i Ni udelima unutar prevlake, presudne su za dalji razvoj različitih endodontskih instrumenata, žica i konzola koje se koriste za ortodontska pomeranja zuba. Aktivne prevlake sa baktericidnim svojstvima i prevlake koje služe kao barijere protiv otpuštanja toksičnih Ni jona iz SMA unutar organizma mogu biti dobijene različitim metodama magnetronskog raspršivanja, pri čemu se različite varijante ove metode mogu uspešno kombinovati. Zbog svega toga u ovom radu je dat pregled ovih metoda, sa njihovim glavnim karakteristikama i nedostacima. Magnetronsko nanošenje raspršivanjem uključuje površinsku modifikaciju SMA u jednoslojnim, višeslojnim, gradiranim slojevima i nanokompozitne tanke prevlake za dobijanje sistema sa superiornim "funkcionalnim" karakteristikama, kao što su vrlo visoka tvrdoća, otpornost na habanje, abraziju i eroziju, poboljšano prijanjanje na različite tehnološki važne supstratne materijale kao što su polimeri, hidrofobnost ili hidrofilnost, dugotrajna hemijska, termička i ekološka stabilnost, nepropusnost gasa i para i drugi. Ovaj rad predstavlja neku vrstu kritičkog pregleda napretka u razvoju magnetronskog raspršivanja modifikovanih SMA proizvoda u stomatologiji, sa unapred predvidljivim fizičko-hemijskim, strukturnim i antimikrobnim osobinama.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Magnetron sputtering methods for surface modification of shape memory alloys for applications in orthodontics and endodontics, Metode magnetronskog raspršivanja za površinsku modifikaciju memorijskih legura za primenu u ortodonciji i endodonciji",
volume = "66",
number = "2",
pages = "87-96",
doi = "10.2478/sdj-2019-0010"
}

Jokanović, V., Čolović, B., Ćetenović, B.,& Živković, S.. (2019). Magnetron sputtering methods for surface modification of shape memory alloys for applications in orthodontics and endodontics. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 66(2), 87-96.
https://doi.org/10.2478/sdj-2019-0010

Jokanović V, Čolović B, Ćetenović B, Živković S. Magnetron sputtering methods for surface modification of shape memory alloys for applications in orthodontics and endodontics. in Stomatološki glasnik Srbije. 2019;66(2):87-96.
doi:10.2478/sdj-2019-0010 .

Jokanović, Vukoman, Čolović, Božana, Ćetenović, Bojana, Živković, Slavoljub, "Magnetron sputtering methods for surface modification of shape memory alloys for applications in orthodontics and endodontics" in Stomatološki glasnik Srbije, 66, no. 2 (2019):87-96,
https://doi.org/10.2478/sdj-2019-0010 . .

TY  - JOUR
AU  - Ćetenović, Bojana
AU  - Marković, Dejan
AU  - Gatman, Džejms
AU  - Perić, Tamara
AU  - Jokanović, Vukoman
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2438
AB  - Introduction/Objective the purpose of this study was to assess effectiveness of endodontic root canal procedures in traumatized permanent teeth with necrotic pulps and chronic periapical lesions after definitive obturation with mineral trioxide aggregate (MTA) products. Adobe Photoshop CS (San Jose, CA, USA) image-analysis software was used for healing assessment. Methods Twenty-seven traumatized single-rooted permanent teeth diagnosed with necrotic pulps and chronic periapical lesions were treated with non-surgical procedure using a tri-antibiotic paste and calcium hydroxide as intra-canal medication. Definitive obturation was performed with ProRoot MTA (Dentsply Tulsa Dental Specialties, Tulsa, OK, USA) or MTA+ Cerkamed (Cerkamed, Stalowa Wola, Poland). Control follow-ups were done three, six, 12, and 24 months following the completion of treatment. Results the positive clinical outcome was recorded in 24 (88.9%) cases, while radiographic success was present in 26 (96.3%) cases. A statistically significant decrease in the sizes of periapical lesions was consistently observed at follow-up periods (p  lt  0.001). There was no statistically significant difference between the two tested MTA materials (p > 0.05). Conclusion the MTA products were effective for the root canal obturation and appeared to contribute to the significant reduction or complete regression of periapical lesions in teeth treated. The presented procedure may be proposed for everyday clinical practice.
AB  - Uvod/Cilj Svrha ove studije bila je procena efikasnosti endodontskog tretmana traumatizovanih stalnih zuba sa nekrotičnom pulpom i hroničnim periapikalnim lezijama posle definitivne opturacije mineralnim trioksidnim agregatom (MTA). Softver za analizu slike Adobe Photoshop CS korišćen je za procenu regeneracije. Metode Dvadeset i sedam traumatizovanih jednokorenih stalnih zuba sa nekrotičnom pulpom i hroničnim periapikalnim lezijama tretirani su nehirurškim procedurama pomoću triantibiotske paste i kalcijum-hidroksida kao intrakanalnog medikamenta. Definitivna opturacija izvedena je pomoću ProRoot MTA ili MTA+ Cerkamed. Kontrolni pregledi obavljeni su tri, šest, 12 i 24 meseca posle završetka lečenja. Rezultati Pozitivan klinički ishod zabeležen je u 24 (88,9%) slučaja, dok je radiografski uspeh bio prisutan u 26 (96,3%) slučaja. Statistički značajno smanjenje veličine periapikalnih lezija primećeno je u svim periodima (p  lt  0,001). Nije bilo statistički značajne razlike između dva testirana MTA materijala (p > 0,05). Zaključak MTA proizvodi su efikasni u opturaciji korenskih kanala i čini se da doprinose značajnom smanjenju ili potpunoj regresiji periapikalnih lezija u tretiranim zubima. Prikazana metodologija može biti predložena za svakodnevnu kliničku praksu.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation: A preliminary study
T1  - Endodontsko lečenje traumatizovanih zuba sa hroničnim periapikalnim lezijama primenom antibiotske paste i opturacije mineralnim trioksidnim agregatom - preliminarna studija
VL  - 147
IS  - 5-6
SP  - 270
EP  - 275
DO  - 10.2298/SARH180301018C
ER  - 

@article{
author = "Ćetenović, Bojana and Marković, Dejan and Gatman, Džejms and Perić, Tamara and Jokanović, Vukoman",
year = "2019",
abstract = "Introduction/Objective the purpose of this study was to assess effectiveness of endodontic root canal procedures in traumatized permanent teeth with necrotic pulps and chronic periapical lesions after definitive obturation with mineral trioxide aggregate (MTA) products. Adobe Photoshop CS (San Jose, CA, USA) image-analysis software was used for healing assessment. Methods Twenty-seven traumatized single-rooted permanent teeth diagnosed with necrotic pulps and chronic periapical lesions were treated with non-surgical procedure using a tri-antibiotic paste and calcium hydroxide as intra-canal medication. Definitive obturation was performed with ProRoot MTA (Dentsply Tulsa Dental Specialties, Tulsa, OK, USA) or MTA+ Cerkamed (Cerkamed, Stalowa Wola, Poland). Control follow-ups were done three, six, 12, and 24 months following the completion of treatment. Results the positive clinical outcome was recorded in 24 (88.9%) cases, while radiographic success was present in 26 (96.3%) cases. A statistically significant decrease in the sizes of periapical lesions was consistently observed at follow-up periods (p  lt  0.001). There was no statistically significant difference between the two tested MTA materials (p > 0.05). Conclusion the MTA products were effective for the root canal obturation and appeared to contribute to the significant reduction or complete regression of periapical lesions in teeth treated. The presented procedure may be proposed for everyday clinical practice., Uvod/Cilj Svrha ove studije bila je procena efikasnosti endodontskog tretmana traumatizovanih stalnih zuba sa nekrotičnom pulpom i hroničnim periapikalnim lezijama posle definitivne opturacije mineralnim trioksidnim agregatom (MTA). Softver za analizu slike Adobe Photoshop CS korišćen je za procenu regeneracije. Metode Dvadeset i sedam traumatizovanih jednokorenih stalnih zuba sa nekrotičnom pulpom i hroničnim periapikalnim lezijama tretirani su nehirurškim procedurama pomoću triantibiotske paste i kalcijum-hidroksida kao intrakanalnog medikamenta. Definitivna opturacija izvedena je pomoću ProRoot MTA ili MTA+ Cerkamed. Kontrolni pregledi obavljeni su tri, šest, 12 i 24 meseca posle završetka lečenja. Rezultati Pozitivan klinički ishod zabeležen je u 24 (88,9%) slučaja, dok je radiografski uspeh bio prisutan u 26 (96,3%) slučaja. Statistički značajno smanjenje veličine periapikalnih lezija primećeno je u svim periodima (p  lt  0,001). Nije bilo statistički značajne razlike između dva testirana MTA materijala (p > 0,05). Zaključak MTA proizvodi su efikasni u opturaciji korenskih kanala i čini se da doprinose značajnom smanjenju ili potpunoj regresiji periapikalnih lezija u tretiranim zubima. Prikazana metodologija može biti predložena za svakodnevnu kliničku praksu.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation: A preliminary study, Endodontsko lečenje traumatizovanih zuba sa hroničnim periapikalnim lezijama primenom antibiotske paste i opturacije mineralnim trioksidnim agregatom - preliminarna studija",
volume = "147",
number = "5-6",
pages = "270-275",
doi = "10.2298/SARH180301018C"
}

Ćetenović, B., Marković, D., Gatman, D., Perić, T.,& Jokanović, V.. (2019). Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation: A preliminary study. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 147(5-6), 270-275.
https://doi.org/10.2298/SARH180301018C

Ćetenović B, Marković D, Gatman D, Perić T, Jokanović V. Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation: A preliminary study. in Srpski arhiv za celokupno lekarstvo. 2019;147(5-6):270-275.
doi:10.2298/SARH180301018C .

Ćetenović, Bojana, Marković, Dejan, Gatman, Džejms, Perić, Tamara, Jokanović, Vukoman, "Endodontic treatment of traumatized teeth with chronic periapical lesions using antibiotic paste and mineral trioxide aggregate obturation: A preliminary study" in Srpski arhiv za celokupno lekarstvo, 147, no. 5-6 (2019):270-275,
https://doi.org/10.2298/SARH180301018C . .

TY  - JOUR
AU  - Trišić, Dijana
AU  - Ćetenović, Bojana
AU  - Zdravković, Nemanja
AU  - Marković, Tatjana
AU  - Dojčinović, Biljana
AU  - Jokanović, Vukoman
AU  - Marković, Dejan
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2444
AB  - Background/Aim. The main task of endodontic treatment is to eliminate pathologically altered tissue, to disinfect root canal space and to obtain its three-dimensional hermetic obturation. The main purpose of this study was to evaluate antimicrobial activity of new endodontic nano-structured highly active calcium silicates based materials albo-mineral plyoxide carbonate aggregate (ALBO-MPCA) and calcium silicates (CS) in comparison to mineral trioxide aggregate (MTA +) and UltraCal XS (CH). Methods. The antimicrobial activity of materials was tested against Staphylococcus aureus (ATCC 25923) and Entero-coccus faecalis (ATCC 14506) strains, and following clinical isolates: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus and Streptococcus vestibularis using a double layer agar diffusion test. The pH measurements were performed using the pH meter. Total amount of released ions was determined by inductively coupled plasma optical emission spectrometry (ICP-OES). Results. All tested materials showed the best antibacterial potential after 1 h of incubation. After 3h and 24h of the incubation period, the an-tibacterial potential of all tested materials were similar. The Agar diffusion test showed that ALBO-MPCA, CS and MTA + had similar inhibition zones (p > 0.05), except in the activity against Staphylococcus aureus where ALBO-MPCA showed better antimicrobial properties than MTA + in 3h and 24h of the incubation period (p  lt  0.05). Following 24h of the incubation, the inhibition zones were the strongest with CH against Staphylococcus aureus (16.67 ± 2.34 mm) followed by ALBO-MPCA (14.67 ± 1.21 mm) and the weakest with CS against Enterococcus faecalis (6.50 ± 1.76 mm). CH showed the highest pH, followed by ALBO-MPCA, CS and MTA +. Conclusion. The expressed antibacterial effects indicate that materials based on nano-structured highly active calcium silicates represent effective therapeutic agents for root canal obturation in one-visit apexification treatment, therefore they are recommend for further examination and clinical trials as they are proposed for MTA substitution.
AB  - Uvod/Cilj. Osnovni cilj endodonskog lečenja je eliminacija patološki izmenjenog tkiva, eliminacija infekcije korensko kanala i njegovo hermetičko trodimenzionalno zatvaranje. Cilj istraživanja je bio da se proceni antibakterijska aktivnost novih endodontskih nano-strukturiranih materijala na bazi visoko aktivnih kalcijum silikata albo-mineral polyoxide carbonate aggregate (ALBO-MPCA) i calcium silicates (CS) u odnosu na mineral trioxide aggregate (MTA +) i UltraCal XS (CH). Metode. Testirana je antibakterijska aktivnost materijala protiv Staphylococcus aureus (ATCC 25923) i Enterococcus faecalis (ATCC 14506), kao i kliničkih izolata: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus i Streptococcus vestibularis pomoću agar difuzionog testa. Merenja pH vred-nosti obavljena su korišćenjem pH metra. Ukupan iznos oslobođenih jona određivan je pomoću ICP-OES. Rezultati. Svi testirani materijali pokazali su najbolji antibakterijski efekat nakon 1 h od inkubacije. Nakon 3 h i 24 h od inkubacije, antibakterijski efekat svih testiranih materijala bio je sličan. Agar difuzioni test pokazao je da materijali ALBOMPCA, CS i MTA+ ispoljavaju slične zone inhibicije rasta (p > 0.05) osim u slučaju Staphylococcus aureus, gde je materijal ALBO-MPCA pokazao bolje antibakterijsko dejstvo nego MTA+ nakon 3 h i 24 h od inkubacije (p  lt  0.05). Nakon 24 h od inkubacije, zone inhibicije su bile najizraženije u slučaju materijala CS protiv Staphylococcus aureus (16.67 ± 2.34 mm), zatim ALBO-MPCA (14.67 ± 1.21 mm), a najslabije u slučaju CS protiv Enterococcus faecalis (6.50±1.76 mm). Materijal CH ispoljio je najveću pH vrednost, zatim ALBOMPCA, CS i MTA+. Zaključak. Ispoljeni antibakterijski efekti ukazuju na to da materijali na bazi visoko aktivnih kalcijum silikata mogu da predstavljaju efikasnu zamenu za MTA u terapiji zuba sa nezavršenim rastom korena u jednoj poseti, te se stoga preporučuju za dalja klinička ispitivanja
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Antibacterial effects of new endodontic materials based on calcium silicates
T1  - Antibakterijski efekti novih endodontskih materijala na bazi kalcijum silikata
VL  - 76
IS  - 4
SP  - 365
EP  - 372
DO  - 10.2298/VSP161231130T
ER  - 

@article{
author = "Trišić, Dijana and Ćetenović, Bojana and Zdravković, Nemanja and Marković, Tatjana and Dojčinović, Biljana and Jokanović, Vukoman and Marković, Dejan",
year = "2019",
abstract = "Background/Aim. The main task of endodontic treatment is to eliminate pathologically altered tissue, to disinfect root canal space and to obtain its three-dimensional hermetic obturation. The main purpose of this study was to evaluate antimicrobial activity of new endodontic nano-structured highly active calcium silicates based materials albo-mineral plyoxide carbonate aggregate (ALBO-MPCA) and calcium silicates (CS) in comparison to mineral trioxide aggregate (MTA +) and UltraCal XS (CH). Methods. The antimicrobial activity of materials was tested against Staphylococcus aureus (ATCC 25923) and Entero-coccus faecalis (ATCC 14506) strains, and following clinical isolates: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus and Streptococcus vestibularis using a double layer agar diffusion test. The pH measurements were performed using the pH meter. Total amount of released ions was determined by inductively coupled plasma optical emission spectrometry (ICP-OES). Results. All tested materials showed the best antibacterial potential after 1 h of incubation. After 3h and 24h of the incubation period, the an-tibacterial potential of all tested materials were similar. The Agar diffusion test showed that ALBO-MPCA, CS and MTA + had similar inhibition zones (p > 0.05), except in the activity against Staphylococcus aureus where ALBO-MPCA showed better antimicrobial properties than MTA + in 3h and 24h of the incubation period (p  lt  0.05). Following 24h of the incubation, the inhibition zones were the strongest with CH against Staphylococcus aureus (16.67 ± 2.34 mm) followed by ALBO-MPCA (14.67 ± 1.21 mm) and the weakest with CS against Enterococcus faecalis (6.50 ± 1.76 mm). CH showed the highest pH, followed by ALBO-MPCA, CS and MTA +. Conclusion. The expressed antibacterial effects indicate that materials based on nano-structured highly active calcium silicates represent effective therapeutic agents for root canal obturation in one-visit apexification treatment, therefore they are recommend for further examination and clinical trials as they are proposed for MTA substitution., Uvod/Cilj. Osnovni cilj endodonskog lečenja je eliminacija patološki izmenjenog tkiva, eliminacija infekcije korensko kanala i njegovo hermetičko trodimenzionalno zatvaranje. Cilj istraživanja je bio da se proceni antibakterijska aktivnost novih endodontskih nano-strukturiranih materijala na bazi visoko aktivnih kalcijum silikata albo-mineral polyoxide carbonate aggregate (ALBO-MPCA) i calcium silicates (CS) u odnosu na mineral trioxide aggregate (MTA +) i UltraCal XS (CH). Metode. Testirana je antibakterijska aktivnost materijala protiv Staphylococcus aureus (ATCC 25923) i Enterococcus faecalis (ATCC 14506), kao i kliničkih izolata: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus i Streptococcus vestibularis pomoću agar difuzionog testa. Merenja pH vred-nosti obavljena su korišćenjem pH metra. Ukupan iznos oslobođenih jona određivan je pomoću ICP-OES. Rezultati. Svi testirani materijali pokazali su najbolji antibakterijski efekat nakon 1 h od inkubacije. Nakon 3 h i 24 h od inkubacije, antibakterijski efekat svih testiranih materijala bio je sličan. Agar difuzioni test pokazao je da materijali ALBOMPCA, CS i MTA+ ispoljavaju slične zone inhibicije rasta (p > 0.05) osim u slučaju Staphylococcus aureus, gde je materijal ALBO-MPCA pokazao bolje antibakterijsko dejstvo nego MTA+ nakon 3 h i 24 h od inkubacije (p  lt  0.05). Nakon 24 h od inkubacije, zone inhibicije su bile najizraženije u slučaju materijala CS protiv Staphylococcus aureus (16.67 ± 2.34 mm), zatim ALBO-MPCA (14.67 ± 1.21 mm), a najslabije u slučaju CS protiv Enterococcus faecalis (6.50±1.76 mm). Materijal CH ispoljio je najveću pH vrednost, zatim ALBOMPCA, CS i MTA+. Zaključak. Ispoljeni antibakterijski efekti ukazuju na to da materijali na bazi visoko aktivnih kalcijum silikata mogu da predstavljaju efikasnu zamenu za MTA u terapiji zuba sa nezavršenim rastom korena u jednoj poseti, te se stoga preporučuju za dalja klinička ispitivanja",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Antibacterial effects of new endodontic materials based on calcium silicates, Antibakterijski efekti novih endodontskih materijala na bazi kalcijum silikata",
volume = "76",
number = "4",
pages = "365-372",
doi = "10.2298/VSP161231130T"
}

Trišić, D., Ćetenović, B., Zdravković, N., Marković, T., Dojčinović, B., Jokanović, V.,& Marković, D.. (2019). Antibacterial effects of new endodontic materials based on calcium silicates. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(4), 365-372.
https://doi.org/10.2298/VSP161231130T

Trišić D, Ćetenović B, Zdravković N, Marković T, Dojčinović B, Jokanović V, Marković D. Antibacterial effects of new endodontic materials based on calcium silicates. in Vojnosanitetski pregled. 2019;76(4):365-372.
doi:10.2298/VSP161231130T .

Trišić, Dijana, Ćetenović, Bojana, Zdravković, Nemanja, Marković, Tatjana, Dojčinović, Biljana, Jokanović, Vukoman, Marković, Dejan, "Antibacterial effects of new endodontic materials based on calcium silicates" in Vojnosanitetski pregled, 76, no. 4 (2019):365-372,
https://doi.org/10.2298/VSP161231130T . .

TY  - JOUR
AU  - Ćetenović, Bojana
AU  - Zdravković, Nemanja
AU  - Marković, Dejan
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2405
AB  - Background/Aim: Toothbrushes are one of the main means of cleaning teeth and maintaining oral hygiene, but toothbrushes are also potential reservoir of microorganisms, including pathogens. The aim of this paper was to evaluate the oral health, oral hygiene awareness and assess the degree of contamination of toothbrushes among students attending Secondary Medical School. Material and Methods: Sixty students (32 boys, 28 girls; mean age ≅ 15,7±2,1) attending highschool were randomly selected for this study. Each student included in the study filled out a questionnaire regarding his/her life habits and oral hygiene. Clinical examinations were initiated in order to determine the DMFT, as well as the CIP, CIT, CIA and CPITN indexes, based of which the assessment of oral health status was performed. One stack of fiber was collected from each toothbrush used by the participantes in the study, and than prepared for further microbiological sampling. Results: Only 11% of the students had the awareness of potential sources of toothbrushes contamination. The average value of DMFT was 3,2 (%D = 22,5; %M = 4,96; %F = 72,5). A statistically significant difference in comparison of the CPITN index and subjects' response to the professional plague removal in the last 12 months was identified (χ2 = 13,55; p= 0,033). Staphylococcus aureus, Streptococcus mutans, Micrococcus species and Streptococcus salivarius were most commonly present microorganisms. In most cases, G-positive bacilli or cocci were isolated, while the presence of Candidae albicans was identified in four samples. Conclusions: Raising the awareness of dental hygiene through the oral health education may improve better plaque control and subsequently the oral health. Hands-on training how to maintain the oral hygiene are not expensive and more over they are easy to be organized can be useful in oral heath promotion.
PB  - Udruženje stomatologa Balkana
T2  - Balkan Journal of Dental Medicine
T1  - Evaluation of toothbrush contamination
VL  - 23
IS  - 2
SP  - 93
EP  - 97
DO  - 10.2478/bjdm-2019-0017
ER  - 

@article{
author = "Ćetenović, Bojana and Zdravković, Nemanja and Marković, Dejan",
year = "2019",
abstract = "Background/Aim: Toothbrushes are one of the main means of cleaning teeth and maintaining oral hygiene, but toothbrushes are also potential reservoir of microorganisms, including pathogens. The aim of this paper was to evaluate the oral health, oral hygiene awareness and assess the degree of contamination of toothbrushes among students attending Secondary Medical School. Material and Methods: Sixty students (32 boys, 28 girls; mean age ≅ 15,7±2,1) attending highschool were randomly selected for this study. Each student included in the study filled out a questionnaire regarding his/her life habits and oral hygiene. Clinical examinations were initiated in order to determine the DMFT, as well as the CIP, CIT, CIA and CPITN indexes, based of which the assessment of oral health status was performed. One stack of fiber was collected from each toothbrush used by the participantes in the study, and than prepared for further microbiological sampling. Results: Only 11% of the students had the awareness of potential sources of toothbrushes contamination. The average value of DMFT was 3,2 (%D = 22,5; %M = 4,96; %F = 72,5). A statistically significant difference in comparison of the CPITN index and subjects' response to the professional plague removal in the last 12 months was identified (χ2 = 13,55; p= 0,033). Staphylococcus aureus, Streptococcus mutans, Micrococcus species and Streptococcus salivarius were most commonly present microorganisms. In most cases, G-positive bacilli or cocci were isolated, while the presence of Candidae albicans was identified in four samples. Conclusions: Raising the awareness of dental hygiene through the oral health education may improve better plaque control and subsequently the oral health. Hands-on training how to maintain the oral hygiene are not expensive and more over they are easy to be organized can be useful in oral heath promotion.",
publisher = "Udruženje stomatologa Balkana",
journal = "Balkan Journal of Dental Medicine",
title = "Evaluation of toothbrush contamination",
volume = "23",
number = "2",
pages = "93-97",
doi = "10.2478/bjdm-2019-0017"
}

Ćetenović, B., Zdravković, N.,& Marković, D.. (2019). Evaluation of toothbrush contamination. in Balkan Journal of Dental Medicine
Udruženje stomatologa Balkana., 23(2), 93-97.
https://doi.org/10.2478/bjdm-2019-0017

Ćetenović B, Zdravković N, Marković D. Evaluation of toothbrush contamination. in Balkan Journal of Dental Medicine. 2019;23(2):93-97.
doi:10.2478/bjdm-2019-0017 .

Ćetenović, Bojana, Zdravković, Nemanja, Marković, Dejan, "Evaluation of toothbrush contamination" in Balkan Journal of Dental Medicine, 23, no. 2 (2019):93-97,
https://doi.org/10.2478/bjdm-2019-0017 . .

TY  - JOUR
AU  - Ćetenović, Bojana
AU  - Čolović, Božana
AU  - Vasilijić, Saša
AU  - Prokić, Bogomir
AU  - Pašalić, Snežana
AU  - Jokanović, Vukoman
AU  - Tepavčević, Zvezdana
AU  - Marković, Dejan
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2275
AB  - The aim of this study was to investigate the biocompatibility of nanostructured materials based on highly active calcium silicates mixed with different radiocontrast agents in comparison to MTA(+) using in vitro and in vivo model. Morphology of materials' samples was analyzed using SEM while the phase compositions were identified by XRD. pH values of materials' suspensions were conducted by pH-meter. The cytotoxicity of materials' solutions was tested by MTT test (100, 50, 25 and 12.5mg/ml). LDH and H-3-thymidine assay were utilized for biocompatibility investigations of materials' eluates (24h, 7 day and 21 day). Eighteen Guinea pigs were used for intramuscular implantation, as teflon tubes with freshly prepared materials were placed into intramuscular pockets. All samples were composed of round and needle-like particles equally distributed with Ca/Si ratio 2.7 at%, with the presence of hydrated calcium silicate phases. The pH values of ALBO-MPCA(1) and ALBO-MPCA(2) were high alkaline, while in case of MTA(+) they were lower and continuously declined (p lt 0.05). Investigated materials didn't exhibit dose-dependent effect on metabolic activity of L929 cells (p>0.05). Significant differences in the percentage of cytotoxicity between diluted and undiluted extracts between all tested materials after 24h and 7 day were noticed (p lt 0.05). Increase in L929 cells proliferation was noticed in case of undiluted eluates of ALBO-MPCA(1) and ALBO-MPCA(2) after 7 day (p lt 0.05). There were no statistically significant differences in the intensity of inflammatory response between investigated materials and control group after 60 day (p>0.05). Evaluation of biocompatibility of both ALBO-MPCA(1) and ALBO-MPCA(2) indicate their potential clinical use. [GRAPHICS] .
PB  - Springer, Dordrecht
T2  - Journal of Materials Science-Materials in Medicine
T1  - Nanostructured endodontic materials mixed with different radiocontrast agentsbiocompatibility study
VL  - 29
IS  - 12
DO  - 10.1007/s10856-018-6200-z
ER  - 

@article{
author = "Ćetenović, Bojana and Čolović, Božana and Vasilijić, Saša and Prokić, Bogomir and Pašalić, Snežana and Jokanović, Vukoman and Tepavčević, Zvezdana and Marković, Dejan",
year = "2018",
abstract = "The aim of this study was to investigate the biocompatibility of nanostructured materials based on highly active calcium silicates mixed with different radiocontrast agents in comparison to MTA(+) using in vitro and in vivo model. Morphology of materials' samples was analyzed using SEM while the phase compositions were identified by XRD. pH values of materials' suspensions were conducted by pH-meter. The cytotoxicity of materials' solutions was tested by MTT test (100, 50, 25 and 12.5mg/ml). LDH and H-3-thymidine assay were utilized for biocompatibility investigations of materials' eluates (24h, 7 day and 21 day). Eighteen Guinea pigs were used for intramuscular implantation, as teflon tubes with freshly prepared materials were placed into intramuscular pockets. All samples were composed of round and needle-like particles equally distributed with Ca/Si ratio 2.7 at%, with the presence of hydrated calcium silicate phases. The pH values of ALBO-MPCA(1) and ALBO-MPCA(2) were high alkaline, while in case of MTA(+) they were lower and continuously declined (p lt 0.05). Investigated materials didn't exhibit dose-dependent effect on metabolic activity of L929 cells (p>0.05). Significant differences in the percentage of cytotoxicity between diluted and undiluted extracts between all tested materials after 24h and 7 day were noticed (p lt 0.05). Increase in L929 cells proliferation was noticed in case of undiluted eluates of ALBO-MPCA(1) and ALBO-MPCA(2) after 7 day (p lt 0.05). There were no statistically significant differences in the intensity of inflammatory response between investigated materials and control group after 60 day (p>0.05). Evaluation of biocompatibility of both ALBO-MPCA(1) and ALBO-MPCA(2) indicate their potential clinical use. [GRAPHICS] .",
publisher = "Springer, Dordrecht",
journal = "Journal of Materials Science-Materials in Medicine",
title = "Nanostructured endodontic materials mixed with different radiocontrast agentsbiocompatibility study",
volume = "29",
number = "12",
doi = "10.1007/s10856-018-6200-z"
}

Ćetenović, B., Čolović, B., Vasilijić, S., Prokić, B., Pašalić, S., Jokanović, V., Tepavčević, Z.,& Marković, D.. (2018). Nanostructured endodontic materials mixed with different radiocontrast agentsbiocompatibility study. in Journal of Materials Science-Materials in Medicine
Springer, Dordrecht., 29(12).
https://doi.org/10.1007/s10856-018-6200-z

Ćetenović B, Čolović B, Vasilijić S, Prokić B, Pašalić S, Jokanović V, Tepavčević Z, Marković D. Nanostructured endodontic materials mixed with different radiocontrast agentsbiocompatibility study. in Journal of Materials Science-Materials in Medicine. 2018;29(12).
doi:10.1007/s10856-018-6200-z .

Ćetenović, Bojana, Čolović, Božana, Vasilijić, Saša, Prokić, Bogomir, Pašalić, Snežana, Jokanović, Vukoman, Tepavčević, Zvezdana, Marković, Dejan, "Nanostructured endodontic materials mixed with different radiocontrast agentsbiocompatibility study" in Journal of Materials Science-Materials in Medicine, 29, no. 12 (2018),
https://doi.org/10.1007/s10856-018-6200-z . .

TY  - JOUR
AU  - Ćetenović, Bojana
AU  - Prokić, Bogomir
AU  - Vasilijić, Saša
AU  - Dojčinović, Biljana
AU  - Magić, Marko
AU  - Jokanović, Vukoman
AU  - Marković, Dejan
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2196
AB  - Introduction: The aim of this article was to analyze biocompatibility and bioactivity of new endodontic materials on the basis of nanosynthesized calcium silicates (ALBO-MPCA(1) and ALBO-MPCA(2)) combined with different radiopacifiers in comparison with MTA(+). Methods: Morphology of the samples was studied by scanning electron microscopy, and the pH and ion release analysis were also assessed. Biocompatibility of materials' eluates (24-hour, 7-day, and 21-day) was conducted by using MIT test. Twelve New Zealand white rabbits were used for intraosseous implantation. Four calvarial defects per animal were created and filled with freshly prepared investigated materials. Results: Samples mostly consisted of agglomerates built up from nanoparticles, preferably spherical and rod-like. There was no significant difference among pH values of materials' eluates after 24 hours (P>.05). The amount of calcium and aluminum ion release decreased, whereas the amount of magnesium and bismuth (ALBO-MPCAl, MTA(+)) and barium (ALBO-MPCA(2)) increased during 21-day period. The metabolic activity of cells increased after the extraction time, except in case of undiluted elutes of ALBO-MPCA(2) and ALBO-MPCAI (21-day). Histologic analysis of the samples revealed newly formed bone tissue with moderate inflammation for all investigated materials, which subsided during 90-day period to mild. Both MIA(+) and ALBO-MPCAI were in direct contact with the newly formed bone tissue. After 90 days, statistically significant difference in hard tissue formation was observed in comparison of MIA(+) and ALBO-MPCki with control group (P  lt .05). Conclusions: Experimental materials ALBOMPCA, and ALBO-MPCA(2) possess both biocompatibility and bioactivity. Because ALBO-MPCAA provokes favorable biological response, it is especially good candidate for further clinical investigations.
PB  - Elsevier Science Inc, New York
T2  - Journal of Endodontics
T1  - Biocompatibility Investigation of New Endodontic Materials Based on Nanosynthesized Calcium Silicates Combined with Different Radiopacifiers
VL  - 43
IS  - 3
SP  - 425
EP  - 432
DO  - 10.1016/j.joen.2016.10.041
ER  - 

@article{
author = "Ćetenović, Bojana and Prokić, Bogomir and Vasilijić, Saša and Dojčinović, Biljana and Magić, Marko and Jokanović, Vukoman and Marković, Dejan",
year = "2017",
abstract = "Introduction: The aim of this article was to analyze biocompatibility and bioactivity of new endodontic materials on the basis of nanosynthesized calcium silicates (ALBO-MPCA(1) and ALBO-MPCA(2)) combined with different radiopacifiers in comparison with MTA(+). Methods: Morphology of the samples was studied by scanning electron microscopy, and the pH and ion release analysis were also assessed. Biocompatibility of materials' eluates (24-hour, 7-day, and 21-day) was conducted by using MIT test. Twelve New Zealand white rabbits were used for intraosseous implantation. Four calvarial defects per animal were created and filled with freshly prepared investigated materials. Results: Samples mostly consisted of agglomerates built up from nanoparticles, preferably spherical and rod-like. There was no significant difference among pH values of materials' eluates after 24 hours (P>.05). The amount of calcium and aluminum ion release decreased, whereas the amount of magnesium and bismuth (ALBO-MPCAl, MTA(+)) and barium (ALBO-MPCA(2)) increased during 21-day period. The metabolic activity of cells increased after the extraction time, except in case of undiluted elutes of ALBO-MPCA(2) and ALBO-MPCAI (21-day). Histologic analysis of the samples revealed newly formed bone tissue with moderate inflammation for all investigated materials, which subsided during 90-day period to mild. Both MIA(+) and ALBO-MPCAI were in direct contact with the newly formed bone tissue. After 90 days, statistically significant difference in hard tissue formation was observed in comparison of MIA(+) and ALBO-MPCki with control group (P  lt .05). Conclusions: Experimental materials ALBOMPCA, and ALBO-MPCA(2) possess both biocompatibility and bioactivity. Because ALBO-MPCAA provokes favorable biological response, it is especially good candidate for further clinical investigations.",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Endodontics",
title = "Biocompatibility Investigation of New Endodontic Materials Based on Nanosynthesized Calcium Silicates Combined with Different Radiopacifiers",
volume = "43",
number = "3",
pages = "425-432",
doi = "10.1016/j.joen.2016.10.041"
}

Ćetenović, B., Prokić, B., Vasilijić, S., Dojčinović, B., Magić, M., Jokanović, V.,& Marković, D.. (2017). Biocompatibility Investigation of New Endodontic Materials Based on Nanosynthesized Calcium Silicates Combined with Different Radiopacifiers. in Journal of Endodontics
Elsevier Science Inc, New York., 43(3), 425-432.
https://doi.org/10.1016/j.joen.2016.10.041

Ćetenović B, Prokić B, Vasilijić S, Dojčinović B, Magić M, Jokanović V, Marković D. Biocompatibility Investigation of New Endodontic Materials Based on Nanosynthesized Calcium Silicates Combined with Different Radiopacifiers. in Journal of Endodontics. 2017;43(3):425-432.
doi:10.1016/j.joen.2016.10.041 .

Ćetenović, Bojana, Prokić, Bogomir, Vasilijić, Saša, Dojčinović, Biljana, Magić, Marko, Jokanović, Vukoman, Marković, Dejan, "Biocompatibility Investigation of New Endodontic Materials Based on Nanosynthesized Calcium Silicates Combined with Different Radiopacifiers" in Journal of Endodontics, 43, no. 3 (2017):425-432,
https://doi.org/10.1016/j.joen.2016.10.041 . .

TY  - JOUR
AU  - Popovska, Lidija
AU  - Dimova, Cena
AU  - Evrosimoska, Biljana
AU  - Stojanovska, Vera
AU  - Muratovska, Ilijana
AU  - Ćetenović, Bojana
AU  - Marković, Dejan
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2253
AB  - Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion. The aim of this study was to determine the quantity of interleukin-1β in the tissues of periapical lesions and to analyze its relationships with: lesion size, previous treatments and pathohistological finding of involved teeth. Methods. Periapical tissues were obtained from patients undergoing periapical surgery. Out of all 80 cases included in the study, 24 had no previous endodontic treatment (open lesions), 37 were with endodontic failure (closed lesion) and in 15 cases root canal retreatment was performed few months before the surgery. By excluding four samples, the total of 76 samples, consisted of periapical lesions and the apical part of the tooth root, was collected. Each periapical tissue sample was divided into two equal parts. The one half of each lesion was used for quantification of interleukin-1β in tissue homogenates by the enzyme-linked immunosorbent assay (ELISA) method. The other part of each lesion was used for histopathological evaluation. Results. For each of the tissue homogenates, the quantity of interleukin-1β was measured, and it ranged from 0.6 pg/mg up to 74 pg/mg. There was no significant difference between the symptomatology and amount of interleukin-1β. Statistical data analysis showed a moderate correlation between lesion size and interleukin-1β measured values. The highest levels of interleukin-1β corresponded with chronic lesions in the stages of acute exacerbation and granulomas in early developing stages. Persistant granulomas, scar tissues, non-inflamed cysts and teeth with recently finished endodontic treatments showed a significantly lower level of interleukin-1β. Conclusion. The study results suggest that the differences in quantity of interleukin-1β correlate to lesion progression and phases of development.
AB  - Uvod/Cilj. Periapikalni periodontitis najčešće je prouzrokovan bakterijskom infekcijom unetom putem kanala zubnog korena i periapikalnom destrukcijom kosti koje predstavlja glavno obeležje ovih lezija. Cilj ovog istraživanja bio je da se odredi količina interleukina-1β u uzorcima periapikalnih lezija i da se analizira njihova povezanost sa: veličinom lezija, postojanjem prethodnih endodontskih tretmana i patohistološkim nalazima. Metode. Ispitivani su uzorci periapikalnih lezija sakupljeni tokom periapikalnih operativnih intervencija. Od svih 80 bolesnika uključenih u studiju, 24 su pripadali bolesnicima koji nisu podvrgnuti endodontskom tretmanu pre apikotomije (otvorene lezije), 37 su tretirani kao endodontski neuspeh (zatvorene lezije), a kod 15 bolesnika endodontski retreatman je sproveden nekoliko meseci pre oralno-hirurške intervencije; četiri uzorka su isključena iz studije. Svaki uzorak koji se sastojao od periapikalne lezije i vrha korena zuba podeljen je na dva jednaka dela. Prva polovina svakog uzorka korišćena je za kvantifikaciju interleukina-1β u tkivnom homogenatu metodom enzyme-linked immunosorbent assay (ELISA). Druga polovina uzorka korišćena je za histopatološku analizu. Rezultati. U svakom tkivnom homogenatu izmerena je količina interleukina-1β, čije vrednosti su se kretale od 0,6 do 74 pg/mg. Naši rezultati nisu potvrdili značajnu razliku između simptomatomatičnih i asimptomatičnih slučajeva; dokazano je prisustvo umerene korelacije između veličine lezija i vrednosti interleukina-1β. Najviše vrednosti interleukina-1β potvrđene su u fazama akutnog pogoršanja hroničnih lezija i kod granuloma u ranim razvojnim fazama. Kod starih granuloma, ožiljačnih tkiva, zuba sa nedavno završenim endodontskim retretmanom i neinflamiranih cista, vrednosti interleukina-1β bile su značajno niže. Zaključak. Rezultati istraživanja pokazuju da su razlike u količini interleukina-1β u korelaciji sa progresijom lezija i fazama njihovog razvoja.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Relationship between IL-1β production and endodontic status of human periapical lesions
T1  - Povezanost stvaranja IL-1β i karakteristika humanih periapikalnih lezija
VL  - 74
IS  - 12
SP  - 1134
EP  - 1139
DO  - 10.2298/VSP151228309P
ER  - 

@article{
author = "Popovska, Lidija and Dimova, Cena and Evrosimoska, Biljana and Stojanovska, Vera and Muratovska, Ilijana and Ćetenović, Bojana and Marković, Dejan",
year = "2017",
abstract = "Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion. The aim of this study was to determine the quantity of interleukin-1β in the tissues of periapical lesions and to analyze its relationships with: lesion size, previous treatments and pathohistological finding of involved teeth. Methods. Periapical tissues were obtained from patients undergoing periapical surgery. Out of all 80 cases included in the study, 24 had no previous endodontic treatment (open lesions), 37 were with endodontic failure (closed lesion) and in 15 cases root canal retreatment was performed few months before the surgery. By excluding four samples, the total of 76 samples, consisted of periapical lesions and the apical part of the tooth root, was collected. Each periapical tissue sample was divided into two equal parts. The one half of each lesion was used for quantification of interleukin-1β in tissue homogenates by the enzyme-linked immunosorbent assay (ELISA) method. The other part of each lesion was used for histopathological evaluation. Results. For each of the tissue homogenates, the quantity of interleukin-1β was measured, and it ranged from 0.6 pg/mg up to 74 pg/mg. There was no significant difference between the symptomatology and amount of interleukin-1β. Statistical data analysis showed a moderate correlation between lesion size and interleukin-1β measured values. The highest levels of interleukin-1β corresponded with chronic lesions in the stages of acute exacerbation and granulomas in early developing stages. Persistant granulomas, scar tissues, non-inflamed cysts and teeth with recently finished endodontic treatments showed a significantly lower level of interleukin-1β. Conclusion. The study results suggest that the differences in quantity of interleukin-1β correlate to lesion progression and phases of development., Uvod/Cilj. Periapikalni periodontitis najčešće je prouzrokovan bakterijskom infekcijom unetom putem kanala zubnog korena i periapikalnom destrukcijom kosti koje predstavlja glavno obeležje ovih lezija. Cilj ovog istraživanja bio je da se odredi količina interleukina-1β u uzorcima periapikalnih lezija i da se analizira njihova povezanost sa: veličinom lezija, postojanjem prethodnih endodontskih tretmana i patohistološkim nalazima. Metode. Ispitivani su uzorci periapikalnih lezija sakupljeni tokom periapikalnih operativnih intervencija. Od svih 80 bolesnika uključenih u studiju, 24 su pripadali bolesnicima koji nisu podvrgnuti endodontskom tretmanu pre apikotomije (otvorene lezije), 37 su tretirani kao endodontski neuspeh (zatvorene lezije), a kod 15 bolesnika endodontski retreatman je sproveden nekoliko meseci pre oralno-hirurške intervencije; četiri uzorka su isključena iz studije. Svaki uzorak koji se sastojao od periapikalne lezije i vrha korena zuba podeljen je na dva jednaka dela. Prva polovina svakog uzorka korišćena je za kvantifikaciju interleukina-1β u tkivnom homogenatu metodom enzyme-linked immunosorbent assay (ELISA). Druga polovina uzorka korišćena je za histopatološku analizu. Rezultati. U svakom tkivnom homogenatu izmerena je količina interleukina-1β, čije vrednosti su se kretale od 0,6 do 74 pg/mg. Naši rezultati nisu potvrdili značajnu razliku između simptomatomatičnih i asimptomatičnih slučajeva; dokazano je prisustvo umerene korelacije između veličine lezija i vrednosti interleukina-1β. Najviše vrednosti interleukina-1β potvrđene su u fazama akutnog pogoršanja hroničnih lezija i kod granuloma u ranim razvojnim fazama. Kod starih granuloma, ožiljačnih tkiva, zuba sa nedavno završenim endodontskim retretmanom i neinflamiranih cista, vrednosti interleukina-1β bile su značajno niže. Zaključak. Rezultati istraživanja pokazuju da su razlike u količini interleukina-1β u korelaciji sa progresijom lezija i fazama njihovog razvoja.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Relationship between IL-1β production and endodontic status of human periapical lesions, Povezanost stvaranja IL-1β i karakteristika humanih periapikalnih lezija",
volume = "74",
number = "12",
pages = "1134-1139",
doi = "10.2298/VSP151228309P"
}

Popovska, L., Dimova, C., Evrosimoska, B., Stojanovska, V., Muratovska, I., Ćetenović, B.,& Marković, D.. (2017). Relationship between IL-1β production and endodontic status of human periapical lesions. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 74(12), 1134-1139.
https://doi.org/10.2298/VSP151228309P

Popovska L, Dimova C, Evrosimoska B, Stojanovska V, Muratovska I, Ćetenović B, Marković D. Relationship between IL-1β production and endodontic status of human periapical lesions. in Vojnosanitetski pregled. 2017;74(12):1134-1139.
doi:10.2298/VSP151228309P .

Popovska, Lidija, Dimova, Cena, Evrosimoska, Biljana, Stojanovska, Vera, Muratovska, Ilijana, Ćetenović, Bojana, Marković, Dejan, "Relationship between IL-1β production and endodontic status of human periapical lesions" in Vojnosanitetski pregled, 74, no. 12 (2017):1134-1139,
https://doi.org/10.2298/VSP151228309P . .

TY  - JOUR
AU  - Ćetenović, Bojana
AU  - Čolović, Božana
AU  - Vasilijić, Saša
AU  - Pašalić, Snežana
AU  - Jokanović, Vukoman
AU  - Marković, Dejan
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2249
AB  - Background/Aim: Lately, fully innovative sol-gel method with high-temperature self-propagating reaction was used for the synthesis of new nanostructured endodontic materials, in combination with different radiopacifiers: bismuth (ALBO-MPCA1) and barium (ALBO-MPCA2). The aim of this study was to investigate the biocompatibility of nanostructured endodontic materials based on highly active calcium silicates and mixed with different radiopacifiers in comparison to MTA+ using human stem cells from the apical papilla- SCAP cells. Material and Methods: Morphology of the samples was studied by SEM. The tested materials were mixed with distilled water in a ratio 2:1 (m/m). Fifteen minutes after the preparation, samples were used in the experiment. The biocompatibility of fresh materials, after 3h and 7 days, was tested using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide- MTT test. Results: Samples mostly consisted of spherical and rode-like. The relative viability of cells increased following the exposure time. Conclusion: The biocompatibility of synthesized materials is comparable to the control material MTA+, and therefore these materials can be recommended for further clinical studies.
PB  - Udruženje stomatologa Balkana
T2  - Balkan Journal of Dental Medicine
T1  - In vitro biocompatibility of nanostructured endodontic materials using SCAP cells
VL  - 21
IS  - 3
SP  - 167
EP  - 170
DO  - 10.1515/bjdm-2017-0029
ER  - 

@article{
author = "Ćetenović, Bojana and Čolović, Božana and Vasilijić, Saša and Pašalić, Snežana and Jokanović, Vukoman and Marković, Dejan",
year = "2017",
abstract = "Background/Aim: Lately, fully innovative sol-gel method with high-temperature self-propagating reaction was used for the synthesis of new nanostructured endodontic materials, in combination with different radiopacifiers: bismuth (ALBO-MPCA1) and barium (ALBO-MPCA2). The aim of this study was to investigate the biocompatibility of nanostructured endodontic materials based on highly active calcium silicates and mixed with different radiopacifiers in comparison to MTA+ using human stem cells from the apical papilla- SCAP cells. Material and Methods: Morphology of the samples was studied by SEM. The tested materials were mixed with distilled water in a ratio 2:1 (m/m). Fifteen minutes after the preparation, samples were used in the experiment. The biocompatibility of fresh materials, after 3h and 7 days, was tested using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide- MTT test. Results: Samples mostly consisted of spherical and rode-like. The relative viability of cells increased following the exposure time. Conclusion: The biocompatibility of synthesized materials is comparable to the control material MTA+, and therefore these materials can be recommended for further clinical studies.",
publisher = "Udruženje stomatologa Balkana",
journal = "Balkan Journal of Dental Medicine",
title = "In vitro biocompatibility of nanostructured endodontic materials using SCAP cells",
volume = "21",
number = "3",
pages = "167-170",
doi = "10.1515/bjdm-2017-0029"
}

Ćetenović, B., Čolović, B., Vasilijić, S., Pašalić, S., Jokanović, V.,& Marković, D.. (2017). In vitro biocompatibility of nanostructured endodontic materials using SCAP cells. in Balkan Journal of Dental Medicine
Udruženje stomatologa Balkana., 21(3), 167-170.
https://doi.org/10.1515/bjdm-2017-0029

Ćetenović B, Čolović B, Vasilijić S, Pašalić S, Jokanović V, Marković D. In vitro biocompatibility of nanostructured endodontic materials using SCAP cells. in Balkan Journal of Dental Medicine. 2017;21(3):167-170.
doi:10.1515/bjdm-2017-0029 .

Ćetenović, Bojana, Čolović, Božana, Vasilijić, Saša, Pašalić, Snežana, Jokanović, Vukoman, Marković, Dejan, "In vitro biocompatibility of nanostructured endodontic materials using SCAP cells" in Balkan Journal of Dental Medicine, 21, no. 3 (2017):167-170,
https://doi.org/10.1515/bjdm-2017-0029 . .

TY  - JOUR
AU  - Trišić, Dijana
AU  - Ćetenović, Bojana
AU  - Jovanović, Igor
AU  - Gjorgievska, Elizabeta
AU  - Popović, Branka
AU  - Marković, Dejan
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2248
AB  - Background/Aim: The aim of this in vitro study was to investigate the influence of irradiation cycles and resting periods, on thermal effects on the external root surface during root canal irradiation of two diode laser systems (940 nm and 975 nm), at output powers of 1 W and 2 W in continuous mode. In previous studies the rising of temperature above 7°C has been reported as biologically accepted to avoid periodontal damage on the external root surface. Material and Methods: Twenty human inferior incisors were randomly distributed into four groups, the 940 nm, and the 975 nm diode laser irradiation, both with an output power of 1 W and 2 W, in continuous mode. The thermographic camera was used to detect temperature variations on the external root surface. Digital radiography of the samples was made. Results: After three cycles of irradiation, at apical third of the root, mean temperature variation by 940 nm diode laser irradiation was 2.88°C for output power of 1 W, and 6.52°C for output power of 2 W. The 975 nm laser caused a higher temperature increase in the apical region, with temperature variation of 13.56°C by an output power of 1 W, and 30.60°C at 2 W, with a statistical significance of p ≤ 0.0001 between two laser systems compared for the same power. The resting periods of 20 s between cycles were enough to lower temperature under 7°C in the case of 1 W and 2 W for 940 nm diode laser, while for 975 nm laser, after three irradiation cycles overheating occurred at both output power rates. Conclusion: Three cycles irradiation of 940 nm diode laser, with resting periods of 20 seconds, allowed safe usage of 1 W and 2 W in CW for endodontic treatment. For 975 nm at a power rate of 1 W, the last resting period drop the temperature near the safe limit and it came under 7°C in a period less than a minute, while at the power of 2 W the resting periods were not long enough for the safe temperature decrease.
PB  - Udruženje stomatologa Balkana
T2  - Balkan Journal of Dental Medicine
T1  - Diode laser irradiation in endodontic therapy through cycles: In vitro study
VL  - 21
IS  - 2
SP  - 108
EP  - 111
DO  - 10.1515/bjdm-2017-0016
ER  - 

@article{
author = "Trišić, Dijana and Ćetenović, Bojana and Jovanović, Igor and Gjorgievska, Elizabeta and Popović, Branka and Marković, Dejan",
year = "2017",
abstract = "Background/Aim: The aim of this in vitro study was to investigate the influence of irradiation cycles and resting periods, on thermal effects on the external root surface during root canal irradiation of two diode laser systems (940 nm and 975 nm), at output powers of 1 W and 2 W in continuous mode. In previous studies the rising of temperature above 7°C has been reported as biologically accepted to avoid periodontal damage on the external root surface. Material and Methods: Twenty human inferior incisors were randomly distributed into four groups, the 940 nm, and the 975 nm diode laser irradiation, both with an output power of 1 W and 2 W, in continuous mode. The thermographic camera was used to detect temperature variations on the external root surface. Digital radiography of the samples was made. Results: After three cycles of irradiation, at apical third of the root, mean temperature variation by 940 nm diode laser irradiation was 2.88°C for output power of 1 W, and 6.52°C for output power of 2 W. The 975 nm laser caused a higher temperature increase in the apical region, with temperature variation of 13.56°C by an output power of 1 W, and 30.60°C at 2 W, with a statistical significance of p ≤ 0.0001 between two laser systems compared for the same power. The resting periods of 20 s between cycles were enough to lower temperature under 7°C in the case of 1 W and 2 W for 940 nm diode laser, while for 975 nm laser, after three irradiation cycles overheating occurred at both output power rates. Conclusion: Three cycles irradiation of 940 nm diode laser, with resting periods of 20 seconds, allowed safe usage of 1 W and 2 W in CW for endodontic treatment. For 975 nm at a power rate of 1 W, the last resting period drop the temperature near the safe limit and it came under 7°C in a period less than a minute, while at the power of 2 W the resting periods were not long enough for the safe temperature decrease.",
publisher = "Udruženje stomatologa Balkana",
journal = "Balkan Journal of Dental Medicine",
title = "Diode laser irradiation in endodontic therapy through cycles: In vitro study",
volume = "21",
number = "2",
pages = "108-111",
doi = "10.1515/bjdm-2017-0016"
}

Trišić, D., Ćetenović, B., Jovanović, I., Gjorgievska, E., Popović, B.,& Marković, D.. (2017). Diode laser irradiation in endodontic therapy through cycles: In vitro study. in Balkan Journal of Dental Medicine
Udruženje stomatologa Balkana., 21(2), 108-111.
https://doi.org/10.1515/bjdm-2017-0016

Trišić D, Ćetenović B, Jovanović I, Gjorgievska E, Popović B, Marković D. Diode laser irradiation in endodontic therapy through cycles: In vitro study. in Balkan Journal of Dental Medicine. 2017;21(2):108-111.
doi:10.1515/bjdm-2017-0016 .

Trišić, Dijana, Ćetenović, Bojana, Jovanović, Igor, Gjorgievska, Elizabeta, Popović, Branka, Marković, Dejan, "Diode laser irradiation in endodontic therapy through cycles: In vitro study" in Balkan Journal of Dental Medicine, 21, no. 2 (2017):108-111,
https://doi.org/10.1515/bjdm-2017-0016 . .

TY  - CHAP
AU  - Marković, Dejan
AU  - Ćetenović, Bojana
AU  - Vuković, Ana
AU  - Jokanović, Vukoman
AU  - Marković, Tatjana
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2154
AB  - Calcium-silicate-based materials are used in many endodontic and oral-surgical procedures. The advantages of calcium-silicate-based materials are good apical sealing, setting in the presence of moisture, and acquiring high pH after mixing. However, these materials also have some disadvantages: low flowability, dry consistency, and long setting time. By applying nanotechnology during synthesis, very active calcium silicate, such as nanostructured mineral polyoxide carbonate aggregate, may be used to overcome the above-mentioned disadvantages and further enhance physical properties of the reaction mixture consisting of calcite and monoclinic bismuth oxide. Application of the sol-gel method for calcite production and combination of such a method with high-temperature, self-propagating synthesis of calcium silicates makes the strategy completely innovative. Materials based on nanostructured calcium silicates may represent effective therapeutic agents for root canal obturation, especially in the case of immature roots. The application of calcium-silicate-based materials may significantly decrease the duration of therapy, reduce the risk of tooth fractures, and overcome incomplete calcification problem.
PB  - Elsevier Inc.
T2  - Nanobiomaterials in Dentistry: Applications of Nanobiomaterials
T1  - Nanosynthesized calcium-silicate-based biomaterials in endodontic treatment of young permanent teeth
VL  - 11
SP  - 269
EP  - 307
DO  - 10.1016/B978-0-323-42867-5.00011-4
ER  - 

@inbook{
author = "Marković, Dejan and Ćetenović, Bojana and Vuković, Ana and Jokanović, Vukoman and Marković, Tatjana",
year = "2016",
abstract = "Calcium-silicate-based materials are used in many endodontic and oral-surgical procedures. The advantages of calcium-silicate-based materials are good apical sealing, setting in the presence of moisture, and acquiring high pH after mixing. However, these materials also have some disadvantages: low flowability, dry consistency, and long setting time. By applying nanotechnology during synthesis, very active calcium silicate, such as nanostructured mineral polyoxide carbonate aggregate, may be used to overcome the above-mentioned disadvantages and further enhance physical properties of the reaction mixture consisting of calcite and monoclinic bismuth oxide. Application of the sol-gel method for calcite production and combination of such a method with high-temperature, self-propagating synthesis of calcium silicates makes the strategy completely innovative. Materials based on nanostructured calcium silicates may represent effective therapeutic agents for root canal obturation, especially in the case of immature roots. The application of calcium-silicate-based materials may significantly decrease the duration of therapy, reduce the risk of tooth fractures, and overcome incomplete calcification problem.",
publisher = "Elsevier Inc.",
journal = "Nanobiomaterials in Dentistry: Applications of Nanobiomaterials",
booktitle = "Nanosynthesized calcium-silicate-based biomaterials in endodontic treatment of young permanent teeth",
volume = "11",
pages = "269-307",
doi = "10.1016/B978-0-323-42867-5.00011-4"
}

Marković, D., Ćetenović, B., Vuković, A., Jokanović, V.,& Marković, T.. (2016). Nanosynthesized calcium-silicate-based biomaterials in endodontic treatment of young permanent teeth. in Nanobiomaterials in Dentistry: Applications of Nanobiomaterials
Elsevier Inc.., 11, 269-307.
https://doi.org/10.1016/B978-0-323-42867-5.00011-4

Marković D, Ćetenović B, Vuković A, Jokanović V, Marković T. Nanosynthesized calcium-silicate-based biomaterials in endodontic treatment of young permanent teeth. in Nanobiomaterials in Dentistry: Applications of Nanobiomaterials. 2016;11:269-307.
doi:10.1016/B978-0-323-42867-5.00011-4 .

Marković, Dejan, Ćetenović, Bojana, Vuković, Ana, Jokanović, Vukoman, Marković, Tatjana, "Nanosynthesized calcium-silicate-based biomaterials in endodontic treatment of young permanent teeth" in Nanobiomaterials in Dentistry: Applications of Nanobiomaterials, 11 (2016):269-307,
https://doi.org/10.1016/B978-0-323-42867-5.00011-4 . .

TY  - THES
AU  - Ćetenović, Bojana
PY  - 2016
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=4587
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:14701/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=48696079
UR  - http://nardus.mpn.gov.rs/123456789/7640
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/998
AB  - Introduction: Biocompatibility is interpreted as the material's ability to act within the adequate host response in a specific situation. The host’s response to foreign body will depend on its chemical reactivity, surface structure and topography. It has been shown that nanostructured surface more closely mimic the hierarchical organization of the bone tissue in comparison to microstructured, by increasing the concentration of active biomolecules that may affect cell migration, adhesion, differentiation and proliferation. During the nineties, mineral trioxide aggregate (MTA) was presented as a material of choice for retrograde fillings because of its lower apical microleakage, setting in the presence of moisture and high pH. Despite some favorable properties, MTA exhibits dry consistency, low flowability and long setting time which limit its clinical use. The aim of this study was to synthesize nanostructured materials based on highly active calcium silicates with enhanced properties and analyze their biocompatibility and bioactivity in comparison to MTA+ (Cerkamed, Stalowa Wola- Poland). Materials and Methods: The sol-gel method in a combination with hightemperature self-propagating reaction was applied for the synthesis of investigated materials. Phase analysis of investigated materials before and after hydratation was performed by XRD and FTIR, while the morphology of the samples was studied by SEM and EDS. The pH measurements were performed using pH-meter, while the amount of released ions was determined using ICP-OES. Biocompatibility of fresh investigated materials and their elutes (24h, 7 and 21 day) was conducted using indirect (MTT), direct test (LDH), proliferation test (3H-thymidine) and direct method (Neutral red). The interaction of directly applied investigated materials with dental pulp tissue was analyzed in an entire human tooth culture model (15 and 30 days). Eighteen guinea pigs received intramuscular sterile polyethylene tubes filled with investigated materials (15, 30 and 60 days). For intraosseous implementation twelve New Zealand white rabbits, divided into two groups (30 and 90 days) were used. Four calvary defects per animal were created with trepan burs and filled with freshly prepared investigated materials. The occurrence of inflammatory responses and hard tissue formation was categorized according to the previously established scores...
AB  - Uvod: Biokompatibilnost se tumači kao sposobnost materijala da deluje uz adekvatan odgovor domaćina u određenoj situaciji. Odgovor domaćina na strano telo zavisiće od njegove hemijske reaktivnosti, površinske strukture i topografije. Dokazano je da nanostrukturirana površina bliže podražava hijerarhijsku organizaciju koštanog tkiva u odnosu na mikrostrukturiranu, povećanjem koncentracije aktivnih biomolekula koji utiču na ćelijsku migraciju, adheziju, diferencijaciju i proliferaciju. Tokom devedesetih godina, mineralni trioksidni agregat (MTA) predstavljen je kao materijal izbora za retrogradne kavitete zbog nižeg apikalnog mikropropuštanja, vezivanja u prisustvu vlage i visoke pH vrednosti. Uprkos povoljnim osobinama, MTA pokazuje suvu konzistenciju, nisku viskoznost i dugo vremena vezivanja, što ograničava njegovu kliničku upotrebu. Cilj ove studije bio je da se sintetišu nanomaterijali na bazi veoma aktivnih kalcijum-silikata unapređenih fizičko-hemijskih svojstava i ispitaju njihova biokompatibilnost i bioaktivnost u odnosu na MTA+ (Cerkamed, Stalowa Wola- Poljska). Materijali i Metod: Postupak sol-gel metode u kombinaciji sa metodom visoko-temperaturne lančane reakcije sagorevanja primenjen je u toku sinteze ispitivanih materijala. Analiza faza pre i posle hidratacija izvedena je pomoću XRD i FTIR, dok je morfologija uzoraka proučavana SEM i EDS. pH merenja su obavljena korišćenjem pH-metra, dok je količina oslobođenih jona određivana korišćenjem ICP-OES. Biokompatibilnost svežih materijala i njihovih ekstrakata (24h, 7 i 21 dan) je ispitana primenom indirektnog testa (MTT), direktnog testa (LDH), testa proliferacije (3H-timidin) i direktnom metodom (Neutralno crvena). Interakcija direktno primenjenih ispitivanih materijala sa pulpnim tkivom analizirana je na modelu kulture humanih zuba (15 i 30 dana). Osamnaest zamorca služilo je za intramišićnu implementaciju sterilnih polietilenskih cevčica ispunjenih ispitivanim materijalima (15, 30 i 60 dana). Za intrakoštani implantacioni test upotrebljeno je dvanaest novozelandskih belih zečeva podeljenih u dve grupe (30 i 90 dana)...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - BIocompatibility investigation of nanosynthesized materials based on calcium silicates and its impact on pulpo-periodontal tissue
T1  - Ispitivanje biokompatibilnosti nanomaterijala na bazi kalcijum silikata i njegovog uticaja na pulpo-parodontalno tkivo
UR  - https://hdl.handle.net/21.15107/rcub_nardus_7640
ER  - 

@phdthesis{
author = "Ćetenović, Bojana",
year = "2016",
abstract = "Introduction: Biocompatibility is interpreted as the material's ability to act within the adequate host response in a specific situation. The host’s response to foreign body will depend on its chemical reactivity, surface structure and topography. It has been shown that nanostructured surface more closely mimic the hierarchical organization of the bone tissue in comparison to microstructured, by increasing the concentration of active biomolecules that may affect cell migration, adhesion, differentiation and proliferation. During the nineties, mineral trioxide aggregate (MTA) was presented as a material of choice for retrograde fillings because of its lower apical microleakage, setting in the presence of moisture and high pH. Despite some favorable properties, MTA exhibits dry consistency, low flowability and long setting time which limit its clinical use. The aim of this study was to synthesize nanostructured materials based on highly active calcium silicates with enhanced properties and analyze their biocompatibility and bioactivity in comparison to MTA+ (Cerkamed, Stalowa Wola- Poland). Materials and Methods: The sol-gel method in a combination with hightemperature self-propagating reaction was applied for the synthesis of investigated materials. Phase analysis of investigated materials before and after hydratation was performed by XRD and FTIR, while the morphology of the samples was studied by SEM and EDS. The pH measurements were performed using pH-meter, while the amount of released ions was determined using ICP-OES. Biocompatibility of fresh investigated materials and their elutes (24h, 7 and 21 day) was conducted using indirect (MTT), direct test (LDH), proliferation test (3H-thymidine) and direct method (Neutral red). The interaction of directly applied investigated materials with dental pulp tissue was analyzed in an entire human tooth culture model (15 and 30 days). Eighteen guinea pigs received intramuscular sterile polyethylene tubes filled with investigated materials (15, 30 and 60 days). For intraosseous implementation twelve New Zealand white rabbits, divided into two groups (30 and 90 days) were used. Four calvary defects per animal were created with trepan burs and filled with freshly prepared investigated materials. The occurrence of inflammatory responses and hard tissue formation was categorized according to the previously established scores..., Uvod: Biokompatibilnost se tumači kao sposobnost materijala da deluje uz adekvatan odgovor domaćina u određenoj situaciji. Odgovor domaćina na strano telo zavisiće od njegove hemijske reaktivnosti, površinske strukture i topografije. Dokazano je da nanostrukturirana površina bliže podražava hijerarhijsku organizaciju koštanog tkiva u odnosu na mikrostrukturiranu, povećanjem koncentracije aktivnih biomolekula koji utiču na ćelijsku migraciju, adheziju, diferencijaciju i proliferaciju. Tokom devedesetih godina, mineralni trioksidni agregat (MTA) predstavljen je kao materijal izbora za retrogradne kavitete zbog nižeg apikalnog mikropropuštanja, vezivanja u prisustvu vlage i visoke pH vrednosti. Uprkos povoljnim osobinama, MTA pokazuje suvu konzistenciju, nisku viskoznost i dugo vremena vezivanja, što ograničava njegovu kliničku upotrebu. Cilj ove studije bio je da se sintetišu nanomaterijali na bazi veoma aktivnih kalcijum-silikata unapređenih fizičko-hemijskih svojstava i ispitaju njihova biokompatibilnost i bioaktivnost u odnosu na MTA+ (Cerkamed, Stalowa Wola- Poljska). Materijali i Metod: Postupak sol-gel metode u kombinaciji sa metodom visoko-temperaturne lančane reakcije sagorevanja primenjen je u toku sinteze ispitivanih materijala. Analiza faza pre i posle hidratacija izvedena je pomoću XRD i FTIR, dok je morfologija uzoraka proučavana SEM i EDS. pH merenja su obavljena korišćenjem pH-metra, dok je količina oslobođenih jona određivana korišćenjem ICP-OES. Biokompatibilnost svežih materijala i njihovih ekstrakata (24h, 7 i 21 dan) je ispitana primenom indirektnog testa (MTT), direktnog testa (LDH), testa proliferacije (3H-timidin) i direktnom metodom (Neutralno crvena). Interakcija direktno primenjenih ispitivanih materijala sa pulpnim tkivom analizirana je na modelu kulture humanih zuba (15 i 30 dana). Osamnaest zamorca služilo je za intramišićnu implementaciju sterilnih polietilenskih cevčica ispunjenih ispitivanim materijalima (15, 30 i 60 dana). Za intrakoštani implantacioni test upotrebljeno je dvanaest novozelandskih belih zečeva podeljenih u dve grupe (30 i 90 dana)...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "BIocompatibility investigation of nanosynthesized materials based on calcium silicates and its impact on pulpo-periodontal tissue, Ispitivanje biokompatibilnosti nanomaterijala na bazi kalcijum silikata i njegovog uticaja na pulpo-parodontalno tkivo",
url = "https://hdl.handle.net/21.15107/rcub_nardus_7640"
}

Ćetenović, B.. (2016). BIocompatibility investigation of nanosynthesized materials based on calcium silicates and its impact on pulpo-periodontal tissue. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_7640

Ćetenović B. BIocompatibility investigation of nanosynthesized materials based on calcium silicates and its impact on pulpo-periodontal tissue. 2016;.
https://hdl.handle.net/21.15107/rcub_nardus_7640 .

Ćetenović, Bojana, "BIocompatibility investigation of nanosynthesized materials based on calcium silicates and its impact on pulpo-periodontal tissue" (2016),
https://hdl.handle.net/21.15107/rcub_nardus_7640 .

TY  - JOUR
AU  - Jokanović, Vukoman
AU  - Čolović, Božana
AU  - Mitrić, Miodrag
AU  - Marković, Dejan
AU  - Ćetenović, Bojana
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1945
AB  - A synthesis of a new dental material, based on nano-structured highly active calcium silicates and calcium carbonates, is described in this paper. Phase analysis of this material, before and after hydration, was performed by X-ray diffraction and showed that active silicate phases were transformed into tobermorite phase, while carbonates remained unchanged. The mechanism of hydration was fully described. The morphology of the sample was studied by SEM, and typical appearance of the present phases was particularly discussed. The mechanical properties and setting time of this material make it very promising for potential application in dental practice.
PB  - Wiley-Blackwell, Hoboken
T2  - International Journal of Applied Ceramic Technology
T1  - Synthesis and Properties of a New Dental Material Based on Nano-Structured Highly Active Calcium Silicates and Calcium Carbonates
VL  - 11
IS  - 1
SP  - 57
EP  - 64
DO  - 10.1111/ijac.12070
ER  - 

@article{
author = "Jokanović, Vukoman and Čolović, Božana and Mitrić, Miodrag and Marković, Dejan and Ćetenović, Bojana",
year = "2014",
abstract = "A synthesis of a new dental material, based on nano-structured highly active calcium silicates and calcium carbonates, is described in this paper. Phase analysis of this material, before and after hydration, was performed by X-ray diffraction and showed that active silicate phases were transformed into tobermorite phase, while carbonates remained unchanged. The mechanism of hydration was fully described. The morphology of the sample was studied by SEM, and typical appearance of the present phases was particularly discussed. The mechanical properties and setting time of this material make it very promising for potential application in dental practice.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "International Journal of Applied Ceramic Technology",
title = "Synthesis and Properties of a New Dental Material Based on Nano-Structured Highly Active Calcium Silicates and Calcium Carbonates",
volume = "11",
number = "1",
pages = "57-64",
doi = "10.1111/ijac.12070"
}

Jokanović, V., Čolović, B., Mitrić, M., Marković, D.,& Ćetenović, B.. (2014). Synthesis and Properties of a New Dental Material Based on Nano-Structured Highly Active Calcium Silicates and Calcium Carbonates. in International Journal of Applied Ceramic Technology
Wiley-Blackwell, Hoboken., 11(1), 57-64.
https://doi.org/10.1111/ijac.12070

Jokanović V, Čolović B, Mitrić M, Marković D, Ćetenović B. Synthesis and Properties of a New Dental Material Based on Nano-Structured Highly Active Calcium Silicates and Calcium Carbonates. in International Journal of Applied Ceramic Technology. 2014;11(1):57-64.
doi:10.1111/ijac.12070 .

Jokanović, Vukoman, Čolović, Božana, Mitrić, Miodrag, Marković, Dejan, Ćetenović, Bojana, "Synthesis and Properties of a New Dental Material Based on Nano-Structured Highly Active Calcium Silicates and Calcium Carbonates" in International Journal of Applied Ceramic Technology, 11, no. 1 (2014):57-64,
https://doi.org/10.1111/ijac.12070 . .

TY  - JOUR
AU  - Ćetenović, Bojana
AU  - Marković, Dejan
AU  - Petrović, Bojan
AU  - Perić, Tamara
AU  - Jokanović, Vukoman
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1803
AB  - Introduction. Dental injuries in immature permanent teeth often result in endodontic complications. Apexification technique using calcium hydroxide is associated with certain flaws, such as long treatment time, the possibility of tooth fracture and incomplete calcification. The use of an apical plug employing mineral trioxide aggregate (MTA) is an alternative treatment option. Case report. We reported the successful treatment of 4 maxillary incisors (in a 7-year-old boy and a 10-year-old girl) with open apices and periapical lesions. Apical portions of the canals were filled with MTA plugs in both cases. Coronal parts of the root canals were filled with gutta-percha and sealer. Clinical findings were clear 6 months after the definite obturation with no pathological changes on the radiographs in both cases. Conclusion. The use of MTA for apical plugging appears to be a valid treatment option in traumatized immature teeth with endodontic complications.
AB  - Uvod. Povrede zuba nezavršenog razvoja korena često su praćene endodontskim komplikacijama. Tehnika apeksifikacije u kojoj se koristi kalcijum-hidroksid povezuje se sa brojnim problemima, kao što su dugotrajnost lečenja, mogućnost frakture korena i neadekvatna kalcifikacija apeksne regije. Stvaranje apeksne barijere korišćenjem mineralnog trioksidnog agregata (MTA) predstavlja alternativu konvencionalnoj tehnici apeksifikacije. Prikaz slučaja. U radu su prikazana dva slučaja uspešnog lečenja hroničnog apeksnog parodontitisa na maksilarnim sekutićima (ukupno četiri) nezavršenog razvoja korena, prvi kod 7-godišnjeg dečaka, a drugi kod 10-godišnje devojčice. U oba slučaja apikalni deo korena zuba napunjen je MTA cementom. Koronarne partije korena zuba napunjene su gutaperkom i pastom. Šest meseci nakon lečenja nije bilo ni kliničkih ni radiografskih znakova patoloških promena. Zaključak. Upotreba MTA kao apeksne barijere pokazuje potencijal validne terapijske opcije kada su u pitanju povređeni zubi nezavršenog razvoja korena sa endodontskim komplikacijama.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Use of mineral trioxide aggregate in the treatment of traumatized teeth in children: Two case reports
T1  - Upotreba mineralnog trioksidnog agregata u lečenju povreda zuba kod dece
VL  - 70
IS  - 8
SP  - 781
EP  - 784
DO  - 10.2298/VSP1308781C
ER  - 

@article{
author = "Ćetenović, Bojana and Marković, Dejan and Petrović, Bojan and Perić, Tamara and Jokanović, Vukoman",
year = "2013",
abstract = "Introduction. Dental injuries in immature permanent teeth often result in endodontic complications. Apexification technique using calcium hydroxide is associated with certain flaws, such as long treatment time, the possibility of tooth fracture and incomplete calcification. The use of an apical plug employing mineral trioxide aggregate (MTA) is an alternative treatment option. Case report. We reported the successful treatment of 4 maxillary incisors (in a 7-year-old boy and a 10-year-old girl) with open apices and periapical lesions. Apical portions of the canals were filled with MTA plugs in both cases. Coronal parts of the root canals were filled with gutta-percha and sealer. Clinical findings were clear 6 months after the definite obturation with no pathological changes on the radiographs in both cases. Conclusion. The use of MTA for apical plugging appears to be a valid treatment option in traumatized immature teeth with endodontic complications., Uvod. Povrede zuba nezavršenog razvoja korena često su praćene endodontskim komplikacijama. Tehnika apeksifikacije u kojoj se koristi kalcijum-hidroksid povezuje se sa brojnim problemima, kao što su dugotrajnost lečenja, mogućnost frakture korena i neadekvatna kalcifikacija apeksne regije. Stvaranje apeksne barijere korišćenjem mineralnog trioksidnog agregata (MTA) predstavlja alternativu konvencionalnoj tehnici apeksifikacije. Prikaz slučaja. U radu su prikazana dva slučaja uspešnog lečenja hroničnog apeksnog parodontitisa na maksilarnim sekutićima (ukupno četiri) nezavršenog razvoja korena, prvi kod 7-godišnjeg dečaka, a drugi kod 10-godišnje devojčice. U oba slučaja apikalni deo korena zuba napunjen je MTA cementom. Koronarne partije korena zuba napunjene su gutaperkom i pastom. Šest meseci nakon lečenja nije bilo ni kliničkih ni radiografskih znakova patoloških promena. Zaključak. Upotreba MTA kao apeksne barijere pokazuje potencijal validne terapijske opcije kada su u pitanju povređeni zubi nezavršenog razvoja korena sa endodontskim komplikacijama.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Use of mineral trioxide aggregate in the treatment of traumatized teeth in children: Two case reports, Upotreba mineralnog trioksidnog agregata u lečenju povreda zuba kod dece",
volume = "70",
number = "8",
pages = "781-784",
doi = "10.2298/VSP1308781C"
}

Ćetenović, B., Marković, D., Petrović, B., Perić, T.,& Jokanović, V.. (2013). Use of mineral trioxide aggregate in the treatment of traumatized teeth in children: Two case reports. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 70(8), 781-784.
https://doi.org/10.2298/VSP1308781C

Ćetenović B, Marković D, Petrović B, Perić T, Jokanović V. Use of mineral trioxide aggregate in the treatment of traumatized teeth in children: Two case reports. in Vojnosanitetski pregled. 2013;70(8):781-784.
doi:10.2298/VSP1308781C .

Ćetenović, Bojana, Marković, Dejan, Petrović, Bojan, Perić, Tamara, Jokanović, Vukoman, "Use of mineral trioxide aggregate in the treatment of traumatized teeth in children: Two case reports" in Vojnosanitetski pregled, 70, no. 8 (2013):781-784,
https://doi.org/10.2298/VSP1308781C . .