TY  - JOUR
AU  - Jekić, B.
AU  - Novaković, I.
AU  - Luković, L
AU  - Kuzmanović, M
AU  - Popović, Branka
AU  - Milašin, Jelena
AU  - Bunjevacki, G
AU  - Damnjanović, Tatjana
AU  - Cvjetičanin, S
AU  - Bunjevački, Vera
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1314
AB  - Myelodysplastic syndromes (MDS) are rare disorders in children. Molecular mechanisims underlying MDS in children are not yet completely understood. Considering the role of FMS and TP53 gene mutations in adult MDS patients, we analyzed nnutations of these genes in a cohort of 35 children with MDS. Single-strand conformation polymorphism polymerase chain reaction analysis performed on FMS codon 969 and TP53 exons 5-9 showed no mutations in the analyzed sequences. Our results Suggest that molecular mechanisms of MDS evolution in children are different from those in adults.
PB  - Elsevier Science Inc, New York
T2  - Cancer Genetics & Cytogenetics
T1  - Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome
VL  - 166
IS  - 2
SP  - 163
EP  - 165
DO  - 10.1016/j.cancergencyto.2005.11.003
ER  - 

@article{
author = "Jekić, B. and Novaković, I. and Luković, L and Kuzmanović, M and Popović, Branka and Milašin, Jelena and Bunjevacki, G and Damnjanović, Tatjana and Cvjetičanin, S and Bunjevački, Vera",
year = "2006",
abstract = "Myelodysplastic syndromes (MDS) are rare disorders in children. Molecular mechanisims underlying MDS in children are not yet completely understood. Considering the role of FMS and TP53 gene mutations in adult MDS patients, we analyzed nnutations of these genes in a cohort of 35 children with MDS. Single-strand conformation polymorphism polymerase chain reaction analysis performed on FMS codon 969 and TP53 exons 5-9 showed no mutations in the analyzed sequences. Our results Suggest that molecular mechanisms of MDS evolution in children are different from those in adults.",
publisher = "Elsevier Science Inc, New York",
journal = "Cancer Genetics & Cytogenetics",
title = "Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome",
volume = "166",
number = "2",
pages = "163-165",
doi = "10.1016/j.cancergencyto.2005.11.003"
}

Jekić, B., Novaković, I., Luković, L., Kuzmanović, M., Popović, B., Milašin, J., Bunjevacki, G., Damnjanović, T., Cvjetičanin, S.,& Bunjevački, V.. (2006). Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome. in Cancer Genetics & Cytogenetics
Elsevier Science Inc, New York., 166(2), 163-165.
https://doi.org/10.1016/j.cancergencyto.2005.11.003

Jekić B, Novaković I, Luković L, Kuzmanović M, Popović B, Milašin J, Bunjevacki G, Damnjanović T, Cvjetičanin S, Bunjevački V. Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome. in Cancer Genetics & Cytogenetics. 2006;166(2):163-165.
doi:10.1016/j.cancergencyto.2005.11.003 .

Jekić, B., Novaković, I., Luković, L, Kuzmanović, M, Popović, Branka, Milašin, Jelena, Bunjevacki, G, Damnjanović, Tatjana, Cvjetičanin, S, Bunjevački, Vera, "Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome" in Cancer Genetics & Cytogenetics, 166, no. 2 (2006):163-165,
https://doi.org/10.1016/j.cancergencyto.2005.11.003 . .

TY  - JOUR
AU  - Novaković, I.
AU  - Bojić, D
AU  - Todorović, S
AU  - Apostolski, Slobodan
AU  - Luković, L
AU  - Stefanović, D
AU  - Milašin, Jelena
PY  - 2005
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1251
AB  - Alterations in production of cytoskeletal protein dystrophin caused by in-frame gene, mutations lead to the Becker muscular dystrophy. In this study we analyzed genotype-phenotype correlation in a group of Becker musculaudystrophy patients with deletions affecting the proximal part of dystrophin gene, encompassing exons 3-13. Four patients with deletions affecting N terminal dystrophin domain had early onset and faster progression of the disease, while three patients with deletions in the proximal part, of dystrophin's rod domain had a more benign disease course. Our study suggests that proximal gene deletions in Becker muscular dystrophy have various phenotypic effects depending on the affected domain of protein dystrophin.
PB  - New York Acad Sciences, New York
T2  - Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus
T1  - Proximal dystrophin gene deletions and protein alterations in Becker muscular dystrophy
VL  - 1048
SP  - 406
EP  - 410
DO  - 10.1196/annals.1342.050
ER  - 

@article{
author = "Novaković, I. and Bojić, D and Todorović, S and Apostolski, Slobodan and Luković, L and Stefanović, D and Milašin, Jelena",
year = "2005",
abstract = "Alterations in production of cytoskeletal protein dystrophin caused by in-frame gene, mutations lead to the Becker muscular dystrophy. In this study we analyzed genotype-phenotype correlation in a group of Becker musculaudystrophy patients with deletions affecting the proximal part of dystrophin gene, encompassing exons 3-13. Four patients with deletions affecting N terminal dystrophin domain had early onset and faster progression of the disease, while three patients with deletions in the proximal part, of dystrophin's rod domain had a more benign disease course. Our study suggests that proximal gene deletions in Becker muscular dystrophy have various phenotypic effects depending on the affected domain of protein dystrophin.",
publisher = "New York Acad Sciences, New York",
journal = "Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus",
title = "Proximal dystrophin gene deletions and protein alterations in Becker muscular dystrophy",
volume = "1048",
pages = "406-410",
doi = "10.1196/annals.1342.050"
}

Novaković, I., Bojić, D., Todorović, S., Apostolski, S., Luković, L., Stefanović, D.,& Milašin, J.. (2005). Proximal dystrophin gene deletions and protein alterations in Becker muscular dystrophy. in Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus
New York Acad Sciences, New York., 1048, 406-410.
https://doi.org/10.1196/annals.1342.050

Novaković I, Bojić D, Todorović S, Apostolski S, Luković L, Stefanović D, Milašin J. Proximal dystrophin gene deletions and protein alterations in Becker muscular dystrophy. in Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus. 2005;1048:406-410.
doi:10.1196/annals.1342.050 .

Novaković, I., Bojić, D, Todorović, S, Apostolski, Slobodan, Luković, L, Stefanović, D, Milašin, Jelena, "Proximal dystrophin gene deletions and protein alterations in Becker muscular dystrophy" in Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus, 1048 (2005):406-410,
https://doi.org/10.1196/annals.1342.050 . .

TY  - JOUR
AU  - Jekić, B.
AU  - Novaković, I.
AU  - Luković, L
AU  - Kuzmanović, M
AU  - Popović, Branka
AU  - Pastar, I
AU  - Milašin, Jelena
AU  - Bunjevacki, G
AU  - Bunjevački, Vera
PY  - 2004
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1224
AB  - In children, myelodysplastic syndromes (MDS) represent less then 10% of all hematological malignancies; consequently, molecular genetic studies dealing with this group of patients are scarce. We have analyzed 35 archival bone marrow samples of children with MDS for the presence of mutations in the first and second exons of the NRAS and KRAS2 genes. Mutations were detected with single-strand conformation polymorphism analysis in three patients. One patient harbored a mutation in the second exon of NRAS and two patients in the second exon of KRAS2. Sequencing was performed in two samples and novel mutations were found in both. One patient had a missense mutation in codon 45 of NRAS; the other had a silent mutation in codon 53 and a missense mutation in codon 55 of KRAS2.
PB  - Elsevier Science Inc, New York
T2  - Cancer Genetics & Cytogenetics
T1  - Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes
VL  - 154
IS  - 2
SP  - 180
EP  - 182
DO  - 10.1016/j.cancergencyto.2004.02.025
ER  - 

@article{
author = "Jekić, B. and Novaković, I. and Luković, L and Kuzmanović, M and Popović, Branka and Pastar, I and Milašin, Jelena and Bunjevacki, G and Bunjevački, Vera",
year = "2004",
abstract = "In children, myelodysplastic syndromes (MDS) represent less then 10% of all hematological malignancies; consequently, molecular genetic studies dealing with this group of patients are scarce. We have analyzed 35 archival bone marrow samples of children with MDS for the presence of mutations in the first and second exons of the NRAS and KRAS2 genes. Mutations were detected with single-strand conformation polymorphism analysis in three patients. One patient harbored a mutation in the second exon of NRAS and two patients in the second exon of KRAS2. Sequencing was performed in two samples and novel mutations were found in both. One patient had a missense mutation in codon 45 of NRAS; the other had a silent mutation in codon 53 and a missense mutation in codon 55 of KRAS2.",
publisher = "Elsevier Science Inc, New York",
journal = "Cancer Genetics & Cytogenetics",
title = "Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes",
volume = "154",
number = "2",
pages = "180-182",
doi = "10.1016/j.cancergencyto.2004.02.025"
}

Jekić, B., Novaković, I., Luković, L., Kuzmanović, M., Popović, B., Pastar, I., Milašin, J., Bunjevacki, G.,& Bunjevački, V.. (2004). Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes. in Cancer Genetics & Cytogenetics
Elsevier Science Inc, New York., 154(2), 180-182.
https://doi.org/10.1016/j.cancergencyto.2004.02.025

Jekić B, Novaković I, Luković L, Kuzmanović M, Popović B, Pastar I, Milašin J, Bunjevacki G, Bunjevački V. Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes. in Cancer Genetics & Cytogenetics. 2004;154(2):180-182.
doi:10.1016/j.cancergencyto.2004.02.025 .

Jekić, B., Novaković, I., Luković, L, Kuzmanović, M, Popović, Branka, Pastar, I, Milašin, Jelena, Bunjevacki, G, Bunjevački, Vera, "Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes" in Cancer Genetics & Cytogenetics, 154, no. 2 (2004):180-182,
https://doi.org/10.1016/j.cancergencyto.2004.02.025 . .

TY  - CONF
AU  - Novaković, I.
AU  - Apostolski, Slobodan
AU  - Todorović, S
AU  - Luković, L
AU  - Bunjevački, Vera
AU  - Bojić, D
AU  - Mestroni, L
AU  - Milašin, Jelena
PY  - 2002
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1144
PB  - Nature Publishing Group, London
C3  - European Journal of Human Genetics
T1  - Cardiac disorders in BMD patients with distal gene deletions
VL  - 10
SP  - 257
EP  - 257
UR  - https://hdl.handle.net/21.15107/rcub_smile_1144
ER  - 

@conference{
author = "Novaković, I. and Apostolski, Slobodan and Todorović, S and Luković, L and Bunjevački, Vera and Bojić, D and Mestroni, L and Milašin, Jelena",
year = "2002",
publisher = "Nature Publishing Group, London",
journal = "European Journal of Human Genetics",
title = "Cardiac disorders in BMD patients with distal gene deletions",
volume = "10",
pages = "257-257",
url = "https://hdl.handle.net/21.15107/rcub_smile_1144"
}

Novaković, I., Apostolski, S., Todorović, S., Luković, L., Bunjevački, V., Bojić, D., Mestroni, L.,& Milašin, J.. (2002). Cardiac disorders in BMD patients with distal gene deletions. in European Journal of Human Genetics
Nature Publishing Group, London., 10, 257-257.
https://hdl.handle.net/21.15107/rcub_smile_1144

Novaković I, Apostolski S, Todorović S, Luković L, Bunjevački V, Bojić D, Mestroni L, Milašin J. Cardiac disorders in BMD patients with distal gene deletions. in European Journal of Human Genetics. 2002;10:257-257.
https://hdl.handle.net/21.15107/rcub_smile_1144 .

Novaković, I., Apostolski, Slobodan, Todorović, S, Luković, L, Bunjevački, Vera, Bojić, D, Mestroni, L, Milašin, Jelena, "Cardiac disorders in BMD patients with distal gene deletions" in European Journal of Human Genetics, 10 (2002):257-257,
https://hdl.handle.net/21.15107/rcub_smile_1144 .