TY  - JOUR
AU  - Čolović, Aleksandra
AU  - Jovičić, Olivera
AU  - Stevanović, Radoje
AU  - Ivanović, Mirjana
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2262
AB  - Background/Aim. Epidermolysis bullosa is a group of rare, genetic connective tissue diseases that cause blisters in the skin and mucosal membranes. The aim of this study was to evaluate the oral health status of patients with epidermolysis bullosa dystrophica and level of knowledge and opinion of parents about the implementation of preventive measures and quality of dental care of affected children. Methods. This study included a group of 17 patients from Serbia suffering from dystrophic epidermolysis bullosa and matched control group. Dental caries status was assessed using the Klein-Palmer index. Oral hygiene status was verified with oral hygiene indices, simplified plaque index, and calculus index as described by Green and Vermillion. The gingiva was assessed as healthy or inflamed (gingivitis) on the basis of any changes in color, shape, size and surface texture. The condition of oral mucosa has been registered on the basis of inspection of the lips, tongue, a floor of the mouth, mouth vestibule and palate. The level of knowledge and the impressions of parents about the application of preventive measures were investigated through two questionnaires specifically designed for this study. Results. In both dentitions, there was the highest percentage of caries teeth. In primary dentition average value of the modified plaque index was 1.4 ± 1.14 and modified calculus was 0.7 ± 1. On permanent teeth average plaque index was 2 ± 0.4, and average calculus 1.6 ± 0.6. Statistically, significant higher values were found in permanent dentition in percentage distribution of decayed, missing, filled teeth and also for plaque and calculus indices between affected children and the control group. Most common findings on mucosa were microstomia (76.5%) and ankyloglossia (88.2%). Conclusion. The absence of protocol between the treating physician and the dentist and not sufficiently informed parents are leading to inadequate dental care. The implementation of preventive measures is of most importance to decrease the risk of severe complications that are difficult to be managed.
AB  - Uvod/Cilj. Bulozna epidermoliza je grupa retkih, genetski predisponiranih bolesti vezivnog tkiva koja se karakteriše formiranjem bula (mehurova) u koži i mukoznim membranama. Cilj rada bio je da se ispita stanje oralnog zdravlja dece obolele od distrofične bulozne epidermolize, kao i nivo znanja i mišljenje roditelja o primeni preventivnih mera i kvalitetu stomatološke zaštite obolele dece. Metode. U studiju je bilo uključeno 17 bolesnika sa distrofičnom buloznom epidermolizom iz Srbije i odgovarajuća kontrolna grupa. Stanje zuba ustanovljeno je Klein Palmerovim indeksom karijesnih, ekstrakovanih plombiranih zuba - KEP indeksom. Stanje oralne higijene analizirano je indeksima oralne higijene (pojednostavljeni plak indeks i indeks zubnog kamenca po Green-Vermillionu). Stanje gingive je na osnovu inspekcije ocenjivano kao zdrava gingiva ili gingivitis, u zavisnosti od toga da li su joj bili promenjeni boja, oblik, veličina ili struktura. Stanje oralne sluzokože evidentirano je na osnovu inspekcije usana, jezika, poda usne duplje, vestibuluma, plika i frenuluma, kao i mekog i tvrdog nepca. Nivo znanja i utisci roditelja o primeni preventivnih mera i kvalitetu stomatološke zaštite dece obolele od bolozne epidermolize, ispitivani su kroz dva upitnika specijalno dizajnirana za potrebe ove studije. Rezultati. U obe denticije bilo je najviše karijesno obolelih zuba. Za mlečnu denticiju prosečan modifikovani plak indeks iznosio je 1,4 ± 1,14, a modifikovani kalkulus indeks 0,7 ± 1. U stalnoj denticiji vrednosti prosečnog plak indesa i kalkulus indeksa redom su bile 2 ± 0,4 i 1,6 ± 0,6. Utvrđena je statistički značajna razlika u procentualnoj zastupljenosti karijesnih, ekstrahovanih i plombiranih zuba stalne denticije između dece obolele od bulozne epidermolize i kontrolne grupe, kao i za vrednosti plak i kalkulus indeksa. Najčešće promene oralne sluzokože bile su mikrostomija (76,5%) i ankiloglosija (88,2%). Zaključak. Odsustvo protokolarne saradnje između ordinirajućeg lekara i stomatologa, kao i nedovoljna informisanost roditelja, glavni su razlozi lošeg stanja oralnog zdravlja. Primena preventivnih mera je od najvećeg značaja kako bi se sprečio nastanak komplikacija koje je teško sanirati kod ove grupe bolesnika.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Oral health status in children with inherited dystrophic epidermolysis bullosa
T1  - Stanje oralnog zdravlja dece obolele od nasledne distrofičke bulozne epidermolize
VL  - 74
IS  - 7
SP  - 644
EP  - 651
DO  - 10.2298/VSP151023159C
ER  - 

@article{
author = "Čolović, Aleksandra and Jovičić, Olivera and Stevanović, Radoje and Ivanović, Mirjana",
year = "2017",
abstract = "Background/Aim. Epidermolysis bullosa is a group of rare, genetic connective tissue diseases that cause blisters in the skin and mucosal membranes. The aim of this study was to evaluate the oral health status of patients with epidermolysis bullosa dystrophica and level of knowledge and opinion of parents about the implementation of preventive measures and quality of dental care of affected children. Methods. This study included a group of 17 patients from Serbia suffering from dystrophic epidermolysis bullosa and matched control group. Dental caries status was assessed using the Klein-Palmer index. Oral hygiene status was verified with oral hygiene indices, simplified plaque index, and calculus index as described by Green and Vermillion. The gingiva was assessed as healthy or inflamed (gingivitis) on the basis of any changes in color, shape, size and surface texture. The condition of oral mucosa has been registered on the basis of inspection of the lips, tongue, a floor of the mouth, mouth vestibule and palate. The level of knowledge and the impressions of parents about the application of preventive measures were investigated through two questionnaires specifically designed for this study. Results. In both dentitions, there was the highest percentage of caries teeth. In primary dentition average value of the modified plaque index was 1.4 ± 1.14 and modified calculus was 0.7 ± 1. On permanent teeth average plaque index was 2 ± 0.4, and average calculus 1.6 ± 0.6. Statistically, significant higher values were found in permanent dentition in percentage distribution of decayed, missing, filled teeth and also for plaque and calculus indices between affected children and the control group. Most common findings on mucosa were microstomia (76.5%) and ankyloglossia (88.2%). Conclusion. The absence of protocol between the treating physician and the dentist and not sufficiently informed parents are leading to inadequate dental care. The implementation of preventive measures is of most importance to decrease the risk of severe complications that are difficult to be managed., Uvod/Cilj. Bulozna epidermoliza je grupa retkih, genetski predisponiranih bolesti vezivnog tkiva koja se karakteriše formiranjem bula (mehurova) u koži i mukoznim membranama. Cilj rada bio je da se ispita stanje oralnog zdravlja dece obolele od distrofične bulozne epidermolize, kao i nivo znanja i mišljenje roditelja o primeni preventivnih mera i kvalitetu stomatološke zaštite obolele dece. Metode. U studiju je bilo uključeno 17 bolesnika sa distrofičnom buloznom epidermolizom iz Srbije i odgovarajuća kontrolna grupa. Stanje zuba ustanovljeno je Klein Palmerovim indeksom karijesnih, ekstrakovanih plombiranih zuba - KEP indeksom. Stanje oralne higijene analizirano je indeksima oralne higijene (pojednostavljeni plak indeks i indeks zubnog kamenca po Green-Vermillionu). Stanje gingive je na osnovu inspekcije ocenjivano kao zdrava gingiva ili gingivitis, u zavisnosti od toga da li su joj bili promenjeni boja, oblik, veličina ili struktura. Stanje oralne sluzokože evidentirano je na osnovu inspekcije usana, jezika, poda usne duplje, vestibuluma, plika i frenuluma, kao i mekog i tvrdog nepca. Nivo znanja i utisci roditelja o primeni preventivnih mera i kvalitetu stomatološke zaštite dece obolele od bolozne epidermolize, ispitivani su kroz dva upitnika specijalno dizajnirana za potrebe ove studije. Rezultati. U obe denticije bilo je najviše karijesno obolelih zuba. Za mlečnu denticiju prosečan modifikovani plak indeks iznosio je 1,4 ± 1,14, a modifikovani kalkulus indeks 0,7 ± 1. U stalnoj denticiji vrednosti prosečnog plak indesa i kalkulus indeksa redom su bile 2 ± 0,4 i 1,6 ± 0,6. Utvrđena je statistički značajna razlika u procentualnoj zastupljenosti karijesnih, ekstrahovanih i plombiranih zuba stalne denticije između dece obolele od bulozne epidermolize i kontrolne grupe, kao i za vrednosti plak i kalkulus indeksa. Najčešće promene oralne sluzokože bile su mikrostomija (76,5%) i ankiloglosija (88,2%). Zaključak. Odsustvo protokolarne saradnje između ordinirajućeg lekara i stomatologa, kao i nedovoljna informisanost roditelja, glavni su razlozi lošeg stanja oralnog zdravlja. Primena preventivnih mera je od najvećeg značaja kako bi se sprečio nastanak komplikacija koje je teško sanirati kod ove grupe bolesnika.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Oral health status in children with inherited dystrophic epidermolysis bullosa, Stanje oralnog zdravlja dece obolele od nasledne distrofičke bulozne epidermolize",
volume = "74",
number = "7",
pages = "644-651",
doi = "10.2298/VSP151023159C"
}

Čolović, A., Jovičić, O., Stevanović, R.,& Ivanović, M.. (2017). Oral health status in children with inherited dystrophic epidermolysis bullosa. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 74(7), 644-651.
https://doi.org/10.2298/VSP151023159C

Čolović A, Jovičić O, Stevanović R, Ivanović M. Oral health status in children with inherited dystrophic epidermolysis bullosa. in Vojnosanitetski pregled. 2017;74(7):644-651.
doi:10.2298/VSP151023159C .

Čolović, Aleksandra, Jovičić, Olivera, Stevanović, Radoje, Ivanović, Mirjana, "Oral health status in children with inherited dystrophic epidermolysis bullosa" in Vojnosanitetski pregled, 74, no. 7 (2017):644-651,
https://doi.org/10.2298/VSP151023159C . .

TY  - THES
AU  - Čolović, Aleksandra
PY  - 2017
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=6836
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:19937/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=1024368782
UR  - http://nardus.mpn.gov.rs/123456789/11272
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1020
AB  - Epidermolysis bullosa (EB) is a genetic multisystem, genetically and clinically heterogeneous group of diseases characterized by extreme sensitivity of the skin and mucous membranes, where blisters and erosions occur after minor mechanical trauma. Patients suffering from epidermolysis bullosa dystrophica (DEB) are highly-risk group of patients for caries and periodontal diseases due to poor oral hygiene, specific diet and changed function of the oral cavity (blisters and erosions on mucousa, microstomia, ankyloglossia, loss of the vestibular space, absence of lingual papillae and palatal folds and enamel hypoplasia). The aim of this study was to determine the level of knowledge and opinions of parents about the implementation of preventive measures and quality of dental care of affected children, then to examine whether there are statistically significant differences in the parameters of oral health status among children with DEB and healthy control group and then to examine whether the oral health status of children with DEB may significantly improve with the continuous and regular use of dental preventive and prophylactic measures. Materials and Methods: This study was conducted at the Clinic for Pediatric and Preventive Dentistry at School of Dental Medicine at the University of Belgrade. Participants of this study included a group of 24 patients (8 (33.0%) female and 16 (67.0%) male sex) suffering from epidermolysis bullosa dystrophica (4 (16.7%) had dominant, and 20 (83.3%) recessive type of epidermolysis bullosa dystrophica) who live on the territory of Serbia and who are in parental custody. Healthy controls were correspondingly matched individually by sex and age (±6 months). The level of knowledge and opinion of parents about the quality of dental care of affected children was obtained by filling a specifically designed questionnaires for this study. In the clinical examination there were investigated and recorded parameters of oral health status: dental status, oral hygiene status, condition of the gingiva and condition of oral mucosa...
AB  - Epidermolysis bullosa (EB) je nasledna multisistemska, genetički i klinički heterogena grupa bolesti koju karakteriše izuzetna osetljivost kože i sluzokoža, na kojima se bule i erozije javljaju nakon slabe mehaničke traume. Pacijenti oboleli od epidermolysis bullosa dystrophica (DEB) predstavljaju visko rizičnu grupu pacijenata za nastanak karijesa i parodontalnih oboljenja zbog loše oralne higijene, posebnog režima ishrane i izmenjene funkcije usne duplje (bule i erozije po sluzokoži, mikrostomija, ankiloglosija, smanjen vestibulum, odsustvo jezičnih papila i palatinalnih plika i hipoplazija gleđi). Cilj ove studije je bio da se utvrdi nivo znanja i mišljenja roditelja o primeni preventivnih mera u stomatologiji i kvalitetu stomatološke zaštite obolele dece, zatim da se ispita da li postoje statistički značajne razlike u vrednostima parametara stanja oralnog zdravlja izmedju dece obolele od DEB i zdrave kontrolne grupe i zatim ispitati da li se stanje oralnog zdravlja dece obolele od DEB može statistički značajno poboljšati kontinuiranom i redovnom primenom stomatoloških preventivnih i profilaktičkih mera. Materijal i metode: Istraživanje je sprovedeno na Klinici za dečju i preventivnu stomatologiju, Stomatološkog fakulteta, Univerziteta u Beogradu. U okviru studije pregledana su 24 pacijenta (8 (33.0%) ženskog i 16 (67.0%) muškog pola) obolela od epidermolysis bullosa dystrophica (4 (16.7%) je imalo dominantan, a 20 (83.3%) recesivan oblik distrofične bulozne epidermolize) koji žive na teritoriji Srbije i koji su na roditeljskom staranju. Kontrolnu grupu predstavljao je isti broj zdrave dece odgovarajudeg pola i uzrasta (±6meseci), koji su odabirani po principu individualnog mečovanja. Nivo znanja i mišljenje roditelja o stomatološkoj zaštiti obolele dece je dobijen popunjavanjem specijalno dizajniranih anketnih upitnika. Na kliničkom pregledu ispitivani su i zabeleženi parametri stanja oralnog zdravlja: stanje zuba, stanje oralne higijene, stanje gingive i stanje oralne sluzokože. Preventivne i profilaktičke mere bile su sprovedene kroz 3 kontrolna pregleda, na 6 meseci, u periodu od godinu i po dana i zabeležene u stomatološki karton pacijenta...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - The possibilites of prevention of oral diseases in children with epidermolysis bullosa dystrophica
T1  - Mogućnosti prevencije oralnih oboljenja kod dece obolele od epidermolysis bullosa dystrophica
UR  - https://hdl.handle.net/21.15107/rcub_nardus_11272
ER  - 

@phdthesis{
author = "Čolović, Aleksandra",
year = "2017",
abstract = "Epidermolysis bullosa (EB) is a genetic multisystem, genetically and clinically heterogeneous group of diseases characterized by extreme sensitivity of the skin and mucous membranes, where blisters and erosions occur after minor mechanical trauma. Patients suffering from epidermolysis bullosa dystrophica (DEB) are highly-risk group of patients for caries and periodontal diseases due to poor oral hygiene, specific diet and changed function of the oral cavity (blisters and erosions on mucousa, microstomia, ankyloglossia, loss of the vestibular space, absence of lingual papillae and palatal folds and enamel hypoplasia). The aim of this study was to determine the level of knowledge and opinions of parents about the implementation of preventive measures and quality of dental care of affected children, then to examine whether there are statistically significant differences in the parameters of oral health status among children with DEB and healthy control group and then to examine whether the oral health status of children with DEB may significantly improve with the continuous and regular use of dental preventive and prophylactic measures. Materials and Methods: This study was conducted at the Clinic for Pediatric and Preventive Dentistry at School of Dental Medicine at the University of Belgrade. Participants of this study included a group of 24 patients (8 (33.0%) female and 16 (67.0%) male sex) suffering from epidermolysis bullosa dystrophica (4 (16.7%) had dominant, and 20 (83.3%) recessive type of epidermolysis bullosa dystrophica) who live on the territory of Serbia and who are in parental custody. Healthy controls were correspondingly matched individually by sex and age (±6 months). The level of knowledge and opinion of parents about the quality of dental care of affected children was obtained by filling a specifically designed questionnaires for this study. In the clinical examination there were investigated and recorded parameters of oral health status: dental status, oral hygiene status, condition of the gingiva and condition of oral mucosa..., Epidermolysis bullosa (EB) je nasledna multisistemska, genetički i klinički heterogena grupa bolesti koju karakteriše izuzetna osetljivost kože i sluzokoža, na kojima se bule i erozije javljaju nakon slabe mehaničke traume. Pacijenti oboleli od epidermolysis bullosa dystrophica (DEB) predstavljaju visko rizičnu grupu pacijenata za nastanak karijesa i parodontalnih oboljenja zbog loše oralne higijene, posebnog režima ishrane i izmenjene funkcije usne duplje (bule i erozije po sluzokoži, mikrostomija, ankiloglosija, smanjen vestibulum, odsustvo jezičnih papila i palatinalnih plika i hipoplazija gleđi). Cilj ove studije je bio da se utvrdi nivo znanja i mišljenja roditelja o primeni preventivnih mera u stomatologiji i kvalitetu stomatološke zaštite obolele dece, zatim da se ispita da li postoje statistički značajne razlike u vrednostima parametara stanja oralnog zdravlja izmedju dece obolele od DEB i zdrave kontrolne grupe i zatim ispitati da li se stanje oralnog zdravlja dece obolele od DEB može statistički značajno poboljšati kontinuiranom i redovnom primenom stomatoloških preventivnih i profilaktičkih mera. Materijal i metode: Istraživanje je sprovedeno na Klinici za dečju i preventivnu stomatologiju, Stomatološkog fakulteta, Univerziteta u Beogradu. U okviru studije pregledana su 24 pacijenta (8 (33.0%) ženskog i 16 (67.0%) muškog pola) obolela od epidermolysis bullosa dystrophica (4 (16.7%) je imalo dominantan, a 20 (83.3%) recesivan oblik distrofične bulozne epidermolize) koji žive na teritoriji Srbije i koji su na roditeljskom staranju. Kontrolnu grupu predstavljao je isti broj zdrave dece odgovarajudeg pola i uzrasta (±6meseci), koji su odabirani po principu individualnog mečovanja. Nivo znanja i mišljenje roditelja o stomatološkoj zaštiti obolele dece je dobijen popunjavanjem specijalno dizajniranih anketnih upitnika. Na kliničkom pregledu ispitivani su i zabeleženi parametri stanja oralnog zdravlja: stanje zuba, stanje oralne higijene, stanje gingive i stanje oralne sluzokože. Preventivne i profilaktičke mere bile su sprovedene kroz 3 kontrolna pregleda, na 6 meseci, u periodu od godinu i po dana i zabeležene u stomatološki karton pacijenta...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "The possibilites of prevention of oral diseases in children with epidermolysis bullosa dystrophica, Mogućnosti prevencije oralnih oboljenja kod dece obolele od epidermolysis bullosa dystrophica",
url = "https://hdl.handle.net/21.15107/rcub_nardus_11272"
}

Čolović, A.. (2017). The possibilites of prevention of oral diseases in children with epidermolysis bullosa dystrophica. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_11272

Čolović A. The possibilites of prevention of oral diseases in children with epidermolysis bullosa dystrophica. 2017;.
https://hdl.handle.net/21.15107/rcub_nardus_11272 .

Čolović, Aleksandra, "The possibilites of prevention of oral diseases in children with epidermolysis bullosa dystrophica" (2017),
https://hdl.handle.net/21.15107/rcub_nardus_11272 .