TY  - JOUR
AU  - Brajović, Gavrilo
AU  - Stefanović, Gordana
AU  - Ilić, Vesna
AU  - Petrović, Sonja
AU  - Stefanović, Neda
AU  - Nikolić-Jakoba, Nataša
AU  - Milošević-Jovčić, Nadežda
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1563
AB  - Background: Fibronectin (FN) can bind to immunoglobulins (Ig), influencing both the normal clearance and abnormal deposition of circulating immune complexes. This study focuses on the possible interaction between FN and IgG present in gingival crevicular fluid (GCF) of periodontitis patients and periodontally healthy controls, with the aim to determine whether such interaction may be connected with the glycosylation profile of IgG and, thus, consequentional in accumulation of proinflammatory IgG in periodontal pockets. Methods: The study included 30 patients with initial or advanced periodontitis, and 13 periodontally healthy subjects. GCF IgG was purified and analyzed for the presence of FN and its fragments and for galactose expression. Results: IgG isolated from GCF contained FN, which was bound to the IgG heavy chains. IgG from GCF of advanced periodontitis patients contained high levels of hypogalactosylated IgG, and bound more FN than IgG from GCF of the other two groups, which contained low levels of this glycoform. FN was in a degraded form in GCF from all studied patients, and a fragment of 48- to 53-kDa molecular mass seemed to be the sole one linked to IgG. Conclusions: IgG and the FN fragment of 48 to 53 kDa in GCF of periodontitis patients and periodontally healthy subjects are physically connected. This fragment was linked to the heavy chains of IgG and the reaction seemed to be particularly intensive with IgG from advanced periodontitis, which contained significantly less galactose in its sugar chains. J Periodontol 2010;81:1472-1480.
PB  - Wiley, Hoboken
T2  - Journal of Periodontology
T1  - Association of Fibronectin With Hypogalactosylated Immunoglobulin G in Gingival Crevicular Fluid in Periodontitis
VL  - 81
IS  - 10
SP  - 1472
EP  - 1480
DO  - 10.1902/jop.2010.100053
ER  - 

@article{
author = "Brajović, Gavrilo and Stefanović, Gordana and Ilić, Vesna and Petrović, Sonja and Stefanović, Neda and Nikolić-Jakoba, Nataša and Milošević-Jovčić, Nadežda",
year = "2010",
abstract = "Background: Fibronectin (FN) can bind to immunoglobulins (Ig), influencing both the normal clearance and abnormal deposition of circulating immune complexes. This study focuses on the possible interaction between FN and IgG present in gingival crevicular fluid (GCF) of periodontitis patients and periodontally healthy controls, with the aim to determine whether such interaction may be connected with the glycosylation profile of IgG and, thus, consequentional in accumulation of proinflammatory IgG in periodontal pockets. Methods: The study included 30 patients with initial or advanced periodontitis, and 13 periodontally healthy subjects. GCF IgG was purified and analyzed for the presence of FN and its fragments and for galactose expression. Results: IgG isolated from GCF contained FN, which was bound to the IgG heavy chains. IgG from GCF of advanced periodontitis patients contained high levels of hypogalactosylated IgG, and bound more FN than IgG from GCF of the other two groups, which contained low levels of this glycoform. FN was in a degraded form in GCF from all studied patients, and a fragment of 48- to 53-kDa molecular mass seemed to be the sole one linked to IgG. Conclusions: IgG and the FN fragment of 48 to 53 kDa in GCF of periodontitis patients and periodontally healthy subjects are physically connected. This fragment was linked to the heavy chains of IgG and the reaction seemed to be particularly intensive with IgG from advanced periodontitis, which contained significantly less galactose in its sugar chains. J Periodontol 2010;81:1472-1480.",
publisher = "Wiley, Hoboken",
journal = "Journal of Periodontology",
title = "Association of Fibronectin With Hypogalactosylated Immunoglobulin G in Gingival Crevicular Fluid in Periodontitis",
volume = "81",
number = "10",
pages = "1472-1480",
doi = "10.1902/jop.2010.100053"
}

Brajović, G., Stefanović, G., Ilić, V., Petrović, S., Stefanović, N., Nikolić-Jakoba, N.,& Milošević-Jovčić, N.. (2010). Association of Fibronectin With Hypogalactosylated Immunoglobulin G in Gingival Crevicular Fluid in Periodontitis. in Journal of Periodontology
Wiley, Hoboken., 81(10), 1472-1480.
https://doi.org/10.1902/jop.2010.100053

Brajović G, Stefanović G, Ilić V, Petrović S, Stefanović N, Nikolić-Jakoba N, Milošević-Jovčić N. Association of Fibronectin With Hypogalactosylated Immunoglobulin G in Gingival Crevicular Fluid in Periodontitis. in Journal of Periodontology. 2010;81(10):1472-1480.
doi:10.1902/jop.2010.100053 .

Brajović, Gavrilo, Stefanović, Gordana, Ilić, Vesna, Petrović, Sonja, Stefanović, Neda, Nikolić-Jakoba, Nataša, Milošević-Jovčić, Nadežda, "Association of Fibronectin With Hypogalactosylated Immunoglobulin G in Gingival Crevicular Fluid in Periodontitis" in Journal of Periodontology, 81, no. 10 (2010):1472-1480,
https://doi.org/10.1902/jop.2010.100053 . .

TY  - ADVS
AU  - Stefanović, Gordana
AU  - Kršljak, Elena
PY  - 2007
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2563
AB  - Video prikazuje eksperimente kojima se dokazuju osobine spinalnih refleksa: refleksno vreme, iradijacija refleksa i prostorna i vremenska sumacija refleksa.
T1  - Osobine spinalnih refleksa
UR  - https://hdl.handle.net/21.15107/rcub_smile_2563
ER  - 

@misc{
author = "Stefanović, Gordana and Kršljak, Elena",
year = "2007",
abstract = "Video prikazuje eksperimente kojima se dokazuju osobine spinalnih refleksa: refleksno vreme, iradijacija refleksa i prostorna i vremenska sumacija refleksa.",
title = "Osobine spinalnih refleksa",
url = "https://hdl.handle.net/21.15107/rcub_smile_2563"
}

Stefanović, G.,& Kršljak, E.. (2007). Osobine spinalnih refleksa. .
https://hdl.handle.net/21.15107/rcub_smile_2563

Stefanović G, Kršljak E. Osobine spinalnih refleksa. 2007;.
https://hdl.handle.net/21.15107/rcub_smile_2563 .

Stefanović, Gordana, Kršljak, Elena, "Osobine spinalnih refleksa" (2007),
https://hdl.handle.net/21.15107/rcub_smile_2563 .

TY  - JOUR
AU  - Ilić, Vesna
AU  - Milošević-Jovčić, Nadežda
AU  - Marković, D.
AU  - Petrović, S.
AU  - Stefanović, Gordana
PY  - 2007
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1346
AB  - The association between a particular Gm haplotype and susceptibility to multiple myeloma (MM) is not clear. The reason is probably because no investigations have so far been carried out on the relationship between the Gm haplotype, which represents the inherited combination of IgG Gm allotypes, and the Gm allotype expressed at the IgG paraprotein (M-component), which reflects the enhanced gene expression within the haplotype in MM. We studied the incidence of Gm allotypic markers present in IgG subclasses in the serum from 52 patients with MM and in parallel with the isolated IgG paraproteins. The results showed that 84.6% of the patients were heterozygous for haplotypes Gm(a; z; n-; g;)/Gm(f; n+/n-; b1; b0; b5) and 15.3% were homozygous for Gm(f; n/n-; b1; b0; b5), while no homozygous Gm(a; z; n-; g) individuals were found among the studied patients. The incidence of these combinations in the healthy population in Serbia is 34%, 66% and  lt  1%, respectively. Subjects with Gm(a; z; n-; g)/Gm(f; n+/n-; b1; b0; b5) combination are over 10 times [odds ratio (OR) = 10.69; 95% confidence interval 1.67-68] as likely to be affected by the disease as the subjects with homozygous Gm(f; n+/n-; b1; b0; b5) combination (OR = 0.35, 95% confidence interval 0.06-2.23). However, despite the Gm heterozygosity, most of the Gm(a; z; n-; g;)/Gm(f; n+/n-; b1; b0; b5) positive patients with MM (86.3%) had IgG paraprotein with the allotypic marker from the Gm(f; n+/n-; b1; b0; b5) haplotype. Together with patients homozygous for this haplotype, the relative number of patients with serum IgG paraprotein carrying allotypic marker from the Gm(f; n/n-; b1; b0; b5) haplotype was 88.5%. These results suggest that the development of an M-component could be related to a disturbance on chromosome 14q32 carrying the Gm (f; n+/n-; b1; b0; b5) set of genes.
PB  - Wiley, Hoboken
T2  - International Journal of Immunogenetics
T1  - A biased Gm haplotype and Gm paraprotein allotype in multiple myeloma suggests a role for the Gm system in myeloma development
VL  - 34
IS  - 2
SP  - 119
EP  - 125
DO  - 10.1111/j.1744-313X.2007.00673.x
ER  - 

@article{
author = "Ilić, Vesna and Milošević-Jovčić, Nadežda and Marković, D. and Petrović, S. and Stefanović, Gordana",
year = "2007",
abstract = "The association between a particular Gm haplotype and susceptibility to multiple myeloma (MM) is not clear. The reason is probably because no investigations have so far been carried out on the relationship between the Gm haplotype, which represents the inherited combination of IgG Gm allotypes, and the Gm allotype expressed at the IgG paraprotein (M-component), which reflects the enhanced gene expression within the haplotype in MM. We studied the incidence of Gm allotypic markers present in IgG subclasses in the serum from 52 patients with MM and in parallel with the isolated IgG paraproteins. The results showed that 84.6% of the patients were heterozygous for haplotypes Gm(a; z; n-; g;)/Gm(f; n+/n-; b1; b0; b5) and 15.3% were homozygous for Gm(f; n/n-; b1; b0; b5), while no homozygous Gm(a; z; n-; g) individuals were found among the studied patients. The incidence of these combinations in the healthy population in Serbia is 34%, 66% and  lt  1%, respectively. Subjects with Gm(a; z; n-; g)/Gm(f; n+/n-; b1; b0; b5) combination are over 10 times [odds ratio (OR) = 10.69; 95% confidence interval 1.67-68] as likely to be affected by the disease as the subjects with homozygous Gm(f; n+/n-; b1; b0; b5) combination (OR = 0.35, 95% confidence interval 0.06-2.23). However, despite the Gm heterozygosity, most of the Gm(a; z; n-; g;)/Gm(f; n+/n-; b1; b0; b5) positive patients with MM (86.3%) had IgG paraprotein with the allotypic marker from the Gm(f; n+/n-; b1; b0; b5) haplotype. Together with patients homozygous for this haplotype, the relative number of patients with serum IgG paraprotein carrying allotypic marker from the Gm(f; n/n-; b1; b0; b5) haplotype was 88.5%. These results suggest that the development of an M-component could be related to a disturbance on chromosome 14q32 carrying the Gm (f; n+/n-; b1; b0; b5) set of genes.",
publisher = "Wiley, Hoboken",
journal = "International Journal of Immunogenetics",
title = "A biased Gm haplotype and Gm paraprotein allotype in multiple myeloma suggests a role for the Gm system in myeloma development",
volume = "34",
number = "2",
pages = "119-125",
doi = "10.1111/j.1744-313X.2007.00673.x"
}

Ilić, V., Milošević-Jovčić, N., Marković, D., Petrović, S.,& Stefanović, G.. (2007). A biased Gm haplotype and Gm paraprotein allotype in multiple myeloma suggests a role for the Gm system in myeloma development. in International Journal of Immunogenetics
Wiley, Hoboken., 34(2), 119-125.
https://doi.org/10.1111/j.1744-313X.2007.00673.x

Ilić V, Milošević-Jovčić N, Marković D, Petrović S, Stefanović G. A biased Gm haplotype and Gm paraprotein allotype in multiple myeloma suggests a role for the Gm system in myeloma development. in International Journal of Immunogenetics. 2007;34(2):119-125.
doi:10.1111/j.1744-313X.2007.00673.x .

Ilić, Vesna, Milošević-Jovčić, Nadežda, Marković, D., Petrović, S., Stefanović, Gordana, "A biased Gm haplotype and Gm paraprotein allotype in multiple myeloma suggests a role for the Gm system in myeloma development" in International Journal of Immunogenetics, 34, no. 2 (2007):119-125,
https://doi.org/10.1111/j.1744-313X.2007.00673.x . .

TY  - ADVS
AU  - Kršljak, Elena
AU  - Stefanović, Gordana
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2548
AB  - Video prikazuje uticaj opterećenja mišića na snagu mišićne kontrakcije.
T1  - Uticaj opterećenja na snagu mišićne kontrakcije
UR  - https://hdl.handle.net/21.15107/rcub_smile_2548
ER  - 

@misc{
author = "Kršljak, Elena and Stefanović, Gordana",
year = "2006",
abstract = "Video prikazuje uticaj opterećenja mišića na snagu mišićne kontrakcije.",
title = "Uticaj opterećenja na snagu mišićne kontrakcije",
url = "https://hdl.handle.net/21.15107/rcub_smile_2548"
}

Kršljak, E.,& Stefanović, G.. (2006). Uticaj opterećenja na snagu mišićne kontrakcije. .
https://hdl.handle.net/21.15107/rcub_smile_2548

Kršljak E, Stefanović G. Uticaj opterećenja na snagu mišićne kontrakcije. 2006;.
https://hdl.handle.net/21.15107/rcub_smile_2548 .

Kršljak, Elena, Stefanović, Gordana, "Uticaj opterećenja na snagu mišićne kontrakcije" (2006),
https://hdl.handle.net/21.15107/rcub_smile_2548 .

TY  - ADVS
AU  - Kršljak, Elena
AU  - Stefanović, Gordana
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2556
AB  - Video prikazuje uticaj frekvencije supraliminalnih nadražaja na nastanak proste i složenih mišićnih kontrakcija (tetanusa).
T1  - Prosta i složena mišićna kontrakcija
UR  - https://hdl.handle.net/21.15107/rcub_smile_2556
ER  - 

@misc{
author = "Kršljak, Elena and Stefanović, Gordana",
year = "2006",
abstract = "Video prikazuje uticaj frekvencije supraliminalnih nadražaja na nastanak proste i složenih mišićnih kontrakcija (tetanusa).",
title = "Prosta i složena mišićna kontrakcija",
url = "https://hdl.handle.net/21.15107/rcub_smile_2556"
}

Kršljak, E.,& Stefanović, G.. (2006). Prosta i složena mišićna kontrakcija. .
https://hdl.handle.net/21.15107/rcub_smile_2556

Kršljak E, Stefanović G. Prosta i složena mišićna kontrakcija. 2006;.
https://hdl.handle.net/21.15107/rcub_smile_2556 .

Kršljak, Elena, Stefanović, Gordana, "Prosta i složena mišićna kontrakcija" (2006),
https://hdl.handle.net/21.15107/rcub_smile_2556 .

TY  - ADVS
AU  - Kršljak, Elena
AU  - Stefanović, Gordana
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2559
AB  - Video prikazuje postupak određivanja minimalnog (pražnog) nadražaja potrebnog za kontrakciju nervno-mišićnog preparata (galvanoskopske noge). U drugom delu video zapisa demonstriran je uticaj primene stimulusa većeg intenziteta na kontrakciju galvanoskopske noge. Video materijal prate odgovarajuće animacije.
T1  - Određivanje praga nadražaja i gradacija mišićnog odgovora
UR  - https://hdl.handle.net/21.15107/rcub_smile_2559
ER  - 

@misc{
author = "Kršljak, Elena and Stefanović, Gordana",
year = "2006",
abstract = "Video prikazuje postupak određivanja minimalnog (pražnog) nadražaja potrebnog za kontrakciju nervno-mišićnog preparata (galvanoskopske noge). U drugom delu video zapisa demonstriran je uticaj primene stimulusa većeg intenziteta na kontrakciju galvanoskopske noge. Video materijal prate odgovarajuće animacije.",
title = "Određivanje praga nadražaja i gradacija mišićnog odgovora",
url = "https://hdl.handle.net/21.15107/rcub_smile_2559"
}

Kršljak, E.,& Stefanović, G.. (2006). Određivanje praga nadražaja i gradacija mišićnog odgovora. .
https://hdl.handle.net/21.15107/rcub_smile_2559

Kršljak E, Stefanović G. Određivanje praga nadražaja i gradacija mišićnog odgovora. 2006;.
https://hdl.handle.net/21.15107/rcub_smile_2559 .

Kršljak, Elena, Stefanović, Gordana, "Određivanje praga nadražaja i gradacija mišićnog odgovora" (2006),
https://hdl.handle.net/21.15107/rcub_smile_2559 .

TY  - ADVS
AU  - Stefanović, Gordana
AU  - Kršljak, Elena
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2565
AB  - Video prikazuje eksperimente kojima se ispituje uticaj temperature na rad žabljeg srca i dokazuje
automatizam srčanog rada.
T1  - Fiziologija srca
UR  - https://hdl.handle.net/21.15107/rcub_smile_2565
ER  - 

@misc{
author = "Stefanović, Gordana and Kršljak, Elena",
year = "2006",
abstract = "Video prikazuje eksperimente kojima se ispituje uticaj temperature na rad žabljeg srca i dokazuje
automatizam srčanog rada.",
title = "Fiziologija srca",
url = "https://hdl.handle.net/21.15107/rcub_smile_2565"
}

Stefanović, G.,& Kršljak, E.. (2006). Fiziologija srca. .
https://hdl.handle.net/21.15107/rcub_smile_2565

Stefanović G, Kršljak E. Fiziologija srca. 2006;.
https://hdl.handle.net/21.15107/rcub_smile_2565 .

Stefanović, Gordana, Kršljak, Elena, "Fiziologija srca" (2006),
https://hdl.handle.net/21.15107/rcub_smile_2565 .

TY  - ADVS
AU  - Kršljak, Elena
AU  - Stefanović, Gordana
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2540
AB  - Video prikazuje eksperiment kojim se ispituje biološki integritet nerva kao i načine na koji se on može uništiti.
T1  - Biološki integritet nerva
UR  - https://hdl.handle.net/21.15107/rcub_smile_2540
ER  - 

@misc{
author = "Kršljak, Elena and Stefanović, Gordana",
year = "2006",
abstract = "Video prikazuje eksperiment kojim se ispituje biološki integritet nerva kao i načine na koji se on može uništiti.",
title = "Biološki integritet nerva",
url = "https://hdl.handle.net/21.15107/rcub_smile_2540"
}

Kršljak, E.,& Stefanović, G.. (2006). Biološki integritet nerva. .
https://hdl.handle.net/21.15107/rcub_smile_2540

Kršljak E, Stefanović G. Biološki integritet nerva. 2006;.
https://hdl.handle.net/21.15107/rcub_smile_2540 .

Kršljak, Elena, Stefanović, Gordana, "Biološki integritet nerva" (2006),
https://hdl.handle.net/21.15107/rcub_smile_2540 .

TY  - JOUR
AU  - Stefanović, Gordana
AU  - Marković, Dragana
AU  - Ilić, Vesna
AU  - Brajović, Gavrilo
AU  - Petrović, Sonja
AU  - Milošević-Jovčić, Nadežda
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1318
AB  - Background: Altered glycosylation of immunoglobulin G (IgG) has been found to affect certain immunological activities of IgG and to correlate with increased inflammation in various disease states. This work deals with the changes in distribution and galactosylation of IgG subclasses present in saliva and gingival crevicular fluid (GCF) of patients with initial and advanced periodontitis and of normal controls. Methods: IgG subclasses were quantified by dot-blot assay, and the degrees of expression of galactose in the total IgG and its individual subclasses were estimated by lectin immunoblot assay after sodium dodecyl sulfate - polyacrylamide gel electrophoresis (SDS-PAGE) separation of IgG and by capture enzyme-linked immunosorbent assay (ELISA), using biotinylated Ricinus communis (RCA-1) and Bandeiraea simplicifolia (BS-II) lectins. Results: The distribution of IgG subclasses in both fluids was found to differ in periodontal patients compared to normal controls. In the periodontitis saliva and GCF, the IgG2 subclass dominated quantitatively, regardless of periodontal status. However, galactose was found to be expressed in IgG heavy chains in normal controls and patients with initial periodontitis but not, or at barely detectable levels, in advanced periodontitis. Conclusion: The results suggest that the shift toward hypo-galactosylated glycoforms may occur during the process of inflammation of the gingiva.
PB  - Amer Acad Periodontology, Chicago
T2  - Journal of Periodontology
T1  - Hypogalactosylation of salivary and gingival fluid immunoglobulin G in patients with advanced periodontitis
VL  - 77
IS  - 11
SP  - 1887
EP  - 1893
DO  - 10.1902/jop.2006.060049
ER  - 

@article{
author = "Stefanović, Gordana and Marković, Dragana and Ilić, Vesna and Brajović, Gavrilo and Petrović, Sonja and Milošević-Jovčić, Nadežda",
year = "2006",
abstract = "Background: Altered glycosylation of immunoglobulin G (IgG) has been found to affect certain immunological activities of IgG and to correlate with increased inflammation in various disease states. This work deals with the changes in distribution and galactosylation of IgG subclasses present in saliva and gingival crevicular fluid (GCF) of patients with initial and advanced periodontitis and of normal controls. Methods: IgG subclasses were quantified by dot-blot assay, and the degrees of expression of galactose in the total IgG and its individual subclasses were estimated by lectin immunoblot assay after sodium dodecyl sulfate - polyacrylamide gel electrophoresis (SDS-PAGE) separation of IgG and by capture enzyme-linked immunosorbent assay (ELISA), using biotinylated Ricinus communis (RCA-1) and Bandeiraea simplicifolia (BS-II) lectins. Results: The distribution of IgG subclasses in both fluids was found to differ in periodontal patients compared to normal controls. In the periodontitis saliva and GCF, the IgG2 subclass dominated quantitatively, regardless of periodontal status. However, galactose was found to be expressed in IgG heavy chains in normal controls and patients with initial periodontitis but not, or at barely detectable levels, in advanced periodontitis. Conclusion: The results suggest that the shift toward hypo-galactosylated glycoforms may occur during the process of inflammation of the gingiva.",
publisher = "Amer Acad Periodontology, Chicago",
journal = "Journal of Periodontology",
title = "Hypogalactosylation of salivary and gingival fluid immunoglobulin G in patients with advanced periodontitis",
volume = "77",
number = "11",
pages = "1887-1893",
doi = "10.1902/jop.2006.060049"
}

Stefanović, G., Marković, D., Ilić, V., Brajović, G., Petrović, S.,& Milošević-Jovčić, N.. (2006). Hypogalactosylation of salivary and gingival fluid immunoglobulin G in patients with advanced periodontitis. in Journal of Periodontology
Amer Acad Periodontology, Chicago., 77(11), 1887-1893.
https://doi.org/10.1902/jop.2006.060049

Stefanović G, Marković D, Ilić V, Brajović G, Petrović S, Milošević-Jovčić N. Hypogalactosylation of salivary and gingival fluid immunoglobulin G in patients with advanced periodontitis. in Journal of Periodontology. 2006;77(11):1887-1893.
doi:10.1902/jop.2006.060049 .

Stefanović, Gordana, Marković, Dragana, Ilić, Vesna, Brajović, Gavrilo, Petrović, Sonja, Milošević-Jovčić, Nadežda, "Hypogalactosylation of salivary and gingival fluid immunoglobulin G in patients with advanced periodontitis" in Journal of Periodontology, 77, no. 11 (2006):1887-1893,
https://doi.org/10.1902/jop.2006.060049 . .

TY  - JOUR
AU  - Stefanović, Gordana
AU  - Ćirić, Dragana
AU  - Ilić, Vesna
AU  - Brajović, Gavrilo
AU  - Petrović, Sonja
AU  - Milošević, Dragan
AU  - Milošević-Jovčić, Nadežda
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1310
AB  - Changed glycosylation of immunoglobulin G (IgG), above all, the expression of thermal galactose, influence to numerous functions of those immunoglobulin and correlate with the inflammatory level in a number of diseases. Aim: This work analyses the distribution of IgG subclasses and the content of thermal galactose in them, in saliva and gingival fluid of the patients with periodontal disease and different gum inflammatory level. Materials and methods: It was used saliva and gingival fluid of 30 adults with clinical picture of periodontal disease and 20 persons with healthy periodontium. The qualification of IgG was done by “dot-blot” procedure and the, and thermal galactose was determined by lectin immunoblot procedure. Results: The division of IgG subclasses in both fluids was different in the patients with periodontal disease and in control samples. In saliva and gingival fluid of the diseased quantitatively dominated IgG2 subclasses, independently from periodontal status. In IgG of both fluids, thermal galactose was exprimated at the healthy periodontium persons (control) and with the person with initial periodontal disease, while at the person with increased periodontal disease the expression of this saccharide wasn’t registered in neither of fluids. Conclusion: The results showed that there is a shift towards hypogalactosyled IgG glikoforms during the process of gum inflammation at the periodontal disease patients.
AB  - Promenjena glikozilacija imunoglobulina G (IgG), pre svega ekspresija terminalne galaktoze, utiče na brojne funkcije ovih imunoglobulina i korelira sa stepenom zapaljenja u mnogim bolestima. Cilj rada: U ovom radu analizirana je distribucija IgG podklasa i sadržaj terminalne galaktoze u njima, u pljuvačci i gingivalnoj tečnosti bolesnika sa parodontopatijom različitog stepena inflamacije gingive. Materijal i metod: Kao materijal u ispitivanjima korišćena je gingivalna tečnost i pljuvačka 30 odraslih osoba sa kliničkom dijagnozom parodontopatija i 20 osoba sa zdravim parodoncijumom. Kvantifikacija IgG urađena je “dot-blot” postupkom, a određivanje terminalne galaktoze lektinskim imunoblot postupkom. Rezultati: Raspodela IgG podklasa u obe tečnosti se razlikovala kod parodontopatija i u kontrolnim uzorcima. I u pljuvačci i u gingivalnoj tečnosti obolelih, kvantitativno je dominirala IgG2 podklasa, nezavisno od parodontalnog statusa. U IgG obe oralne tečnosti terminalna galaktoza je bila eksprimirana kod osoba sa zdravim parodoncijumom (kontrola) i kod osoba sa početnom (inicijalnom) parodontopatijom, dok kod osoba sa uznapredovalom parodontopatijom ekspresija ovog šećera nije registrovana ni u jednoj od ove dve tečnosti. Zaključak: Rezultati ovih istraživanja ukazuju da postoji pomeranje prema hipogalaktozilovanim IgG glikoformama tokom procesa inflamacije gingive u obolelih od parodontopatije.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Hypogalactosylation of immunoglobulin G (IgG) of gingival fluid and saliva at the patient with periodontal disease
T1  - Hipogalaktozilacija imunoglobulina G (IgG) gingivalne tečnosti i pljuvačke u obolelih od parodontopatije
VL  - 53
IS  - 1
SP  - 7
EP  - 16
DO  - 10.2298/SGS0601007S
ER  - 

@article{
author = "Stefanović, Gordana and Ćirić, Dragana and Ilić, Vesna and Brajović, Gavrilo and Petrović, Sonja and Milošević, Dragan and Milošević-Jovčić, Nadežda",
year = "2006",
abstract = "Changed glycosylation of immunoglobulin G (IgG), above all, the expression of thermal galactose, influence to numerous functions of those immunoglobulin and correlate with the inflammatory level in a number of diseases. Aim: This work analyses the distribution of IgG subclasses and the content of thermal galactose in them, in saliva and gingival fluid of the patients with periodontal disease and different gum inflammatory level. Materials and methods: It was used saliva and gingival fluid of 30 adults with clinical picture of periodontal disease and 20 persons with healthy periodontium. The qualification of IgG was done by “dot-blot” procedure and the, and thermal galactose was determined by lectin immunoblot procedure. Results: The division of IgG subclasses in both fluids was different in the patients with periodontal disease and in control samples. In saliva and gingival fluid of the diseased quantitatively dominated IgG2 subclasses, independently from periodontal status. In IgG of both fluids, thermal galactose was exprimated at the healthy periodontium persons (control) and with the person with initial periodontal disease, while at the person with increased periodontal disease the expression of this saccharide wasn’t registered in neither of fluids. Conclusion: The results showed that there is a shift towards hypogalactosyled IgG glikoforms during the process of gum inflammation at the periodontal disease patients., Promenjena glikozilacija imunoglobulina G (IgG), pre svega ekspresija terminalne galaktoze, utiče na brojne funkcije ovih imunoglobulina i korelira sa stepenom zapaljenja u mnogim bolestima. Cilj rada: U ovom radu analizirana je distribucija IgG podklasa i sadržaj terminalne galaktoze u njima, u pljuvačci i gingivalnoj tečnosti bolesnika sa parodontopatijom različitog stepena inflamacije gingive. Materijal i metod: Kao materijal u ispitivanjima korišćena je gingivalna tečnost i pljuvačka 30 odraslih osoba sa kliničkom dijagnozom parodontopatija i 20 osoba sa zdravim parodoncijumom. Kvantifikacija IgG urađena je “dot-blot” postupkom, a određivanje terminalne galaktoze lektinskim imunoblot postupkom. Rezultati: Raspodela IgG podklasa u obe tečnosti se razlikovala kod parodontopatija i u kontrolnim uzorcima. I u pljuvačci i u gingivalnoj tečnosti obolelih, kvantitativno je dominirala IgG2 podklasa, nezavisno od parodontalnog statusa. U IgG obe oralne tečnosti terminalna galaktoza je bila eksprimirana kod osoba sa zdravim parodoncijumom (kontrola) i kod osoba sa početnom (inicijalnom) parodontopatijom, dok kod osoba sa uznapredovalom parodontopatijom ekspresija ovog šećera nije registrovana ni u jednoj od ove dve tečnosti. Zaključak: Rezultati ovih istraživanja ukazuju da postoji pomeranje prema hipogalaktozilovanim IgG glikoformama tokom procesa inflamacije gingive u obolelih od parodontopatije.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Hypogalactosylation of immunoglobulin G (IgG) of gingival fluid and saliva at the patient with periodontal disease, Hipogalaktozilacija imunoglobulina G (IgG) gingivalne tečnosti i pljuvačke u obolelih od parodontopatije",
volume = "53",
number = "1",
pages = "7-16",
doi = "10.2298/SGS0601007S"
}

Stefanović, G., Ćirić, D., Ilić, V., Brajović, G., Petrović, S., Milošević, D.,& Milošević-Jovčić, N.. (2006). Hypogalactosylation of immunoglobulin G (IgG) of gingival fluid and saliva at the patient with periodontal disease. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 53(1), 7-16.
https://doi.org/10.2298/SGS0601007S

Stefanović G, Ćirić D, Ilić V, Brajović G, Petrović S, Milošević D, Milošević-Jovčić N. Hypogalactosylation of immunoglobulin G (IgG) of gingival fluid and saliva at the patient with periodontal disease. in Stomatološki glasnik Srbije. 2006;53(1):7-16.
doi:10.2298/SGS0601007S .

Stefanović, Gordana, Ćirić, Dragana, Ilić, Vesna, Brajović, Gavrilo, Petrović, Sonja, Milošević, Dragan, Milošević-Jovčić, Nadežda, "Hypogalactosylation of immunoglobulin G (IgG) of gingival fluid and saliva at the patient with periodontal disease" in Stomatološki glasnik Srbije, 53, no. 1 (2006):7-16,
https://doi.org/10.2298/SGS0601007S . .

TY  - JOUR
AU  - Todorović, Tatjana
AU  - Dožić, Ivan
AU  - Pavlica, Dušan
AU  - Marković, Dejan
AU  - Ivanović, Mirjana
AU  - Brajović, Gavrilo
AU  - Stefanović, Gordana
AU  - Mirković, Silvija
AU  - Anđelski, Biljana
PY  - 2005
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1233
AB  - Saliva is a secretion of the salivary and mucous glands and is of major importance in the maintainance of oral health. Over the last few decades, saliva has been evaluated as a diagnostic fluid in medicine for determining systemic disease markers as well as for monitoring numerous drugs, narcotics, and hormones. The biochemical analysis of saliva is particularly important in dentistry. The estimation of the risk of appearance and diagnosis of disease, monitoring of disease progression, evaluation of therapy efficacy for caries, periodontitis, premalignant and malignant oral lesions, as well as infectious diseases of the oral cavity, can be assessed by analyzing different constituent: of saliva, individuals at risk of caries can be identified using test: that determine saliva flow rate, saliva buffer capacity, and colonization of the oral cavity by cariogenic bacteria. Today, these rapid and simple diagnostic tests are used routinely in caries risk determination. The study and use of saliva-based diagnostics have increased over the last few decades. Clinical testing of saliva shows much promise. However, there is a need for much additional research in this area, before the true clinical value of saliva as a diagnostic fluid in dentistry can be determined.
AB  - Pljuvačka je sekret pljuvačnih i mukoznih žlezda koji je značajan za održavanje oralnog zdravlja. Poslednjih decenija sve više se razmatra mogućnost njene primene kao zamena krvi, odnosno krvnom serumu i plazme, radi dokazivanja pokazatelja sistemskih oboljenja, kao i za nadgledanje primene lekova, droga i hormona. Analiziranje biohemijskog sastava pljuvačke posebno je značajno u stomatologiji za procenu rizika nastanka, praćenja toka bolesti i kontrole rezultata primenjenog lečenja zubnog karijesa, parodontopatije, oralnih karcinoma i infektivnih oboljenja usne duplje. U proceni rizika nastanka karijesa na zubima rutinski se izvode ispitivanja kojima se određuju količina izlučene pljuvačke, njen puferski kapacitet i stepen kolonizacije usne duplje kariogenim vrstama bakterija. Jednostavnost izvođenja ovih ispitivanja omogućava da ih u stomatološkoj ordinaciji primenjuje lekar praktičar, što predstavlja veliku pomoć u proceni rizika za nastanak zubnog karijesa. Zbog bliskog kontakta s oralnim tkivima, pljuvačka sadrži brojne biohemijske pokazatelje patoloških procesa lokalizovanih u ovim tkivima (enzimi, imunoglobulini, ostali proteini, fenotipski pokazatelji). Ispitivanje pomenutih pokazatelja je značajno kao dopuna kliničkom dijagnostikovanju ukoliko ono ne pruža dovoljno informacija.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Use of saliva as a diagnostic fluid in dentistry
T1  - Mogućnosti upotrebe pljuvačke kao dijagnostičke tečnosti u stomatologiji
VL  - 133
IS  - 7-8
SP  - 372
EP  - 378
DO  - 10.2298/SARH0508372T
ER  - 

@article{
author = "Todorović, Tatjana and Dožić, Ivan and Pavlica, Dušan and Marković, Dejan and Ivanović, Mirjana and Brajović, Gavrilo and Stefanović, Gordana and Mirković, Silvija and Anđelski, Biljana",
year = "2005",
abstract = "Saliva is a secretion of the salivary and mucous glands and is of major importance in the maintainance of oral health. Over the last few decades, saliva has been evaluated as a diagnostic fluid in medicine for determining systemic disease markers as well as for monitoring numerous drugs, narcotics, and hormones. The biochemical analysis of saliva is particularly important in dentistry. The estimation of the risk of appearance and diagnosis of disease, monitoring of disease progression, evaluation of therapy efficacy for caries, periodontitis, premalignant and malignant oral lesions, as well as infectious diseases of the oral cavity, can be assessed by analyzing different constituent: of saliva, individuals at risk of caries can be identified using test: that determine saliva flow rate, saliva buffer capacity, and colonization of the oral cavity by cariogenic bacteria. Today, these rapid and simple diagnostic tests are used routinely in caries risk determination. The study and use of saliva-based diagnostics have increased over the last few decades. Clinical testing of saliva shows much promise. However, there is a need for much additional research in this area, before the true clinical value of saliva as a diagnostic fluid in dentistry can be determined., Pljuvačka je sekret pljuvačnih i mukoznih žlezda koji je značajan za održavanje oralnog zdravlja. Poslednjih decenija sve više se razmatra mogućnost njene primene kao zamena krvi, odnosno krvnom serumu i plazme, radi dokazivanja pokazatelja sistemskih oboljenja, kao i za nadgledanje primene lekova, droga i hormona. Analiziranje biohemijskog sastava pljuvačke posebno je značajno u stomatologiji za procenu rizika nastanka, praćenja toka bolesti i kontrole rezultata primenjenog lečenja zubnog karijesa, parodontopatije, oralnih karcinoma i infektivnih oboljenja usne duplje. U proceni rizika nastanka karijesa na zubima rutinski se izvode ispitivanja kojima se određuju količina izlučene pljuvačke, njen puferski kapacitet i stepen kolonizacije usne duplje kariogenim vrstama bakterija. Jednostavnost izvođenja ovih ispitivanja omogućava da ih u stomatološkoj ordinaciji primenjuje lekar praktičar, što predstavlja veliku pomoć u proceni rizika za nastanak zubnog karijesa. Zbog bliskog kontakta s oralnim tkivima, pljuvačka sadrži brojne biohemijske pokazatelje patoloških procesa lokalizovanih u ovim tkivima (enzimi, imunoglobulini, ostali proteini, fenotipski pokazatelji). Ispitivanje pomenutih pokazatelja je značajno kao dopuna kliničkom dijagnostikovanju ukoliko ono ne pruža dovoljno informacija.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Use of saliva as a diagnostic fluid in dentistry, Mogućnosti upotrebe pljuvačke kao dijagnostičke tečnosti u stomatologiji",
volume = "133",
number = "7-8",
pages = "372-378",
doi = "10.2298/SARH0508372T"
}

Todorović, T., Dožić, I., Pavlica, D., Marković, D., Ivanović, M., Brajović, G., Stefanović, G., Mirković, S.,& Anđelski, B.. (2005). Use of saliva as a diagnostic fluid in dentistry. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 133(7-8), 372-378.
https://doi.org/10.2298/SARH0508372T

Todorović T, Dožić I, Pavlica D, Marković D, Ivanović M, Brajović G, Stefanović G, Mirković S, Anđelski B. Use of saliva as a diagnostic fluid in dentistry. in Srpski arhiv za celokupno lekarstvo. 2005;133(7-8):372-378.
doi:10.2298/SARH0508372T .

Todorović, Tatjana, Dožić, Ivan, Pavlica, Dušan, Marković, Dejan, Ivanović, Mirjana, Brajović, Gavrilo, Stefanović, Gordana, Mirković, Silvija, Anđelski, Biljana, "Use of saliva as a diagnostic fluid in dentistry" in Srpski arhiv za celokupno lekarstvo, 133, no. 7-8 (2005):372-378,
https://doi.org/10.2298/SARH0508372T . .

TY  - JOUR
AU  - Anđelković, I.
AU  - Stefanović, Gordana
AU  - Kršljak, Elena
AU  - Janković, V
AU  - Bosnić, O
AU  - Durić, D
AU  - Kojić, Z
AU  - Rosić, M
PY  - 1996
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1074
PB  - Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd
T2  - Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry
T1  - The influence of aging on serum levels of rabbits lipoproteins in experimental atherosclerosis
VL  - 15
IS  - 4
SP  - 279
EP  - 280
UR  - https://hdl.handle.net/21.15107/rcub_smile_1074
ER  - 

@article{
author = "Anđelković, I. and Stefanović, Gordana and Kršljak, Elena and Janković, V and Bosnić, O and Durić, D and Kojić, Z and Rosić, M",
year = "1996",
publisher = "Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd",
journal = "Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry",
title = "The influence of aging on serum levels of rabbits lipoproteins in experimental atherosclerosis",
volume = "15",
number = "4",
pages = "279-280",
url = "https://hdl.handle.net/21.15107/rcub_smile_1074"
}

Anđelković, I., Stefanović, G., Kršljak, E., Janković, V., Bosnić, O., Durić, D., Kojić, Z.,& Rosić, M.. (1996). The influence of aging on serum levels of rabbits lipoproteins in experimental atherosclerosis. in Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry
Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd., 15(4), 279-280.
https://hdl.handle.net/21.15107/rcub_smile_1074

Anđelković I, Stefanović G, Kršljak E, Janković V, Bosnić O, Durić D, Kojić Z, Rosić M. The influence of aging on serum levels of rabbits lipoproteins in experimental atherosclerosis. in Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry. 1996;15(4):279-280.
https://hdl.handle.net/21.15107/rcub_smile_1074 .

Anđelković, I., Stefanović, Gordana, Kršljak, Elena, Janković, V, Bosnić, O, Durić, D, Kojić, Z, Rosić, M, "The influence of aging on serum levels of rabbits lipoproteins in experimental atherosclerosis" in Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry, 15, no. 4 (1996):279-280,
https://hdl.handle.net/21.15107/rcub_smile_1074 .

TY  - JOUR
AU  - Rosić, M
AU  - Pantović, S.
AU  - Lucić, S
AU  - Kostić, G
AU  - Stefanović, Gordana
AU  - Kršljak, Elena
AU  - Anđelković, I.
PY  - 1996
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1072
PB  - Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd
T2  - Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry
T1  - Histamine concentration in children suffering from allergic asthma
VL  - 15
IS  - 4
SP  - 237
EP  - 237
UR  - https://hdl.handle.net/21.15107/rcub_smile_1072
ER  - 

@article{
author = "Rosić, M and Pantović, S. and Lucić, S and Kostić, G and Stefanović, Gordana and Kršljak, Elena and Anđelković, I.",
year = "1996",
publisher = "Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd",
journal = "Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry",
title = "Histamine concentration in children suffering from allergic asthma",
volume = "15",
number = "4",
pages = "237-237",
url = "https://hdl.handle.net/21.15107/rcub_smile_1072"
}

Rosić, M., Pantović, S., Lucić, S., Kostić, G., Stefanović, G., Kršljak, E.,& Anđelković, I.. (1996). Histamine concentration in children suffering from allergic asthma. in Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry
Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd., 15(4), 237-237.
https://hdl.handle.net/21.15107/rcub_smile_1072

Rosić M, Pantović S, Lucić S, Kostić G, Stefanović G, Kršljak E, Anđelković I. Histamine concentration in children suffering from allergic asthma. in Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry. 1996;15(4):237-237.
https://hdl.handle.net/21.15107/rcub_smile_1072 .

Rosić, M, Pantović, S., Lucić, S, Kostić, G, Stefanović, Gordana, Kršljak, Elena, Anđelković, I., "Histamine concentration in children suffering from allergic asthma" in Jugoslovenska Medicinska Biohemija - Yugoslav Medical Biochemistry, 15, no. 4 (1996):237-237,
https://hdl.handle.net/21.15107/rcub_smile_1072 .

TY  - THES
AU  - Stefanović, Gordana
PY  - 1987
UR  - https://plus.sr.cobiss.net/opac7/bib/2577679
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/221
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Fizičkohemijske i imunohemijske osobine proteina zubne plake
UR  - https://hdl.handle.net/21.15107/rcub_smile_221
ER  - 

@phdthesis{
author = "Stefanović, Gordana",
year = "1987",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Fizičkohemijske i imunohemijske osobine proteina zubne plake",
url = "https://hdl.handle.net/21.15107/rcub_smile_221"
}

Stefanović, G.. (1987). Fizičkohemijske i imunohemijske osobine proteina zubne plake. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_221

Stefanović G. Fizičkohemijske i imunohemijske osobine proteina zubne plake. 1987;.
https://hdl.handle.net/21.15107/rcub_smile_221 .

Stefanović, Gordana, "Fizičkohemijske i imunohemijske osobine proteina zubne plake" (1987),
https://hdl.handle.net/21.15107/rcub_smile_221 .

TY  - THES
AU  - Stefanović, Gordana
PY  - 1980
UR  - https://plus.sr.cobiss.net/opac7/bib/1024078478
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/125
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Identifikacija i proučavanje serumskih i sekretornih komponenata parotidne pljuvačke
UR  - https://hdl.handle.net/21.15107/rcub_smile_125
ER  - 

@mastersthesis{
author = "Stefanović, Gordana",
year = "1980",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Identifikacija i proučavanje serumskih i sekretornih komponenata parotidne pljuvačke",
url = "https://hdl.handle.net/21.15107/rcub_smile_125"
}

Stefanović, G.. (1980). Identifikacija i proučavanje serumskih i sekretornih komponenata parotidne pljuvačke. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_125

Stefanović G. Identifikacija i proučavanje serumskih i sekretornih komponenata parotidne pljuvačke. 1980;.
https://hdl.handle.net/21.15107/rcub_smile_125 .

Stefanović, Gordana, "Identifikacija i proučavanje serumskih i sekretornih komponenata parotidne pljuvačke" (1980),
https://hdl.handle.net/21.15107/rcub_smile_125 .