TY  - JOUR
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Evica
AU  - Mandinić, Zoran
AU  - Curcić, Marijana
AU  - Cupic-Miladinović, Dejana
AU  - Antonijević, Biljana
AU  - Matović, Vesna
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2414
AB  - Background/Aim. Fluoride has beneficial effect on dental caries prevention and enables high hardness of enamel. However, fluoride intake above optimal levels can have adverse effects on teeth and bones, especially in young children during the period of intense growth and teeth development. The aim of this study was to assess fluoride intake from water and toothpaste among 3-year-old children in Belgrade, Serbia, in the municipalities of Vracar and Novi Beograd. Methods. A questionnaire for the parents (n = 40) was used to provide information on the water consumption (tap and/or bottled water) and the brand of toothpaste used by children as well as the frequency of tooth brushing and the amount of toothpaste during brushing. Fluoride concentrations in water and toothpaste samples were determined electrochemically by using fluoride-selective electrode. Fluoride intake was estimated through a mathematical model commonly used by the U.S. Environmental Protection Agency. Results. The obtained results indicate no significant difference in daily fluoride intake through drinking water and tooth-paste in 3-year-old children in Vracar (n = 19) compared to Novi Beograd (n = 21) (p > 0.05). However, all estimated fluoride levels (0.089-0.625 mg/day) are significantly lower than the optimal daily intake level for caries protection (0.7 mg/day for children up to 4 years, FNB-USA National Institute of Medicine) and two to six times lower than tolerable upper fluoride level for the children of same age (1.3 mg/day, FNB-USA National Institute of Medicine). Furthermore, calculated daily fluoride intake per kilogram body weight confirm very low fluoride intake by water and toothpaste in children of investigated municipalities in Belgrade, being significantly below the recommended an adequate intake (0.05 mg/kg/day, EFSA). Conclusion. This preliminary study has shown that daily fluoride intake in 3-year-olds is lower than tolerable upper fluoride level, even not sufficient for the prevention of dental caries.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia
VL  - 76
IS  - 6
SP  - 607
EP  - 614
DO  - 10.2298/VSP170721136D
ER  - 

@article{
author = "Đukić-Ćosić, Danijela and Antonijević, Evica and Mandinić, Zoran and Curcić, Marijana and Cupic-Miladinović, Dejana and Antonijević, Biljana and Matović, Vesna",
year = "2019",
abstract = "Background/Aim. Fluoride has beneficial effect on dental caries prevention and enables high hardness of enamel. However, fluoride intake above optimal levels can have adverse effects on teeth and bones, especially in young children during the period of intense growth and teeth development. The aim of this study was to assess fluoride intake from water and toothpaste among 3-year-old children in Belgrade, Serbia, in the municipalities of Vracar and Novi Beograd. Methods. A questionnaire for the parents (n = 40) was used to provide information on the water consumption (tap and/or bottled water) and the brand of toothpaste used by children as well as the frequency of tooth brushing and the amount of toothpaste during brushing. Fluoride concentrations in water and toothpaste samples were determined electrochemically by using fluoride-selective electrode. Fluoride intake was estimated through a mathematical model commonly used by the U.S. Environmental Protection Agency. Results. The obtained results indicate no significant difference in daily fluoride intake through drinking water and tooth-paste in 3-year-old children in Vracar (n = 19) compared to Novi Beograd (n = 21) (p > 0.05). However, all estimated fluoride levels (0.089-0.625 mg/day) are significantly lower than the optimal daily intake level for caries protection (0.7 mg/day for children up to 4 years, FNB-USA National Institute of Medicine) and two to six times lower than tolerable upper fluoride level for the children of same age (1.3 mg/day, FNB-USA National Institute of Medicine). Furthermore, calculated daily fluoride intake per kilogram body weight confirm very low fluoride intake by water and toothpaste in children of investigated municipalities in Belgrade, being significantly below the recommended an adequate intake (0.05 mg/kg/day, EFSA). Conclusion. This preliminary study has shown that daily fluoride intake in 3-year-olds is lower than tolerable upper fluoride level, even not sufficient for the prevention of dental caries.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia",
volume = "76",
number = "6",
pages = "607-614",
doi = "10.2298/VSP170721136D"
}

Đukić-Ćosić, D., Antonijević, E., Mandinić, Z., Curcić, M., Cupic-Miladinović, D., Antonijević, B.,& Matović, V.. (2019). Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(6), 607-614.
https://doi.org/10.2298/VSP170721136D

Đukić-Ćosić D, Antonijević E, Mandinić Z, Curcić M, Cupic-Miladinović D, Antonijević B, Matović V. Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia. in Vojnosanitetski pregled. 2019;76(6):607-614.
doi:10.2298/VSP170721136D .

Đukić-Ćosić, Danijela, Antonijević, Evica, Mandinić, Zoran, Curcić, Marijana, Cupic-Miladinović, Dejana, Antonijević, Biljana, Matović, Vesna, "Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: preliminary results in Belgrade, Republic of Serbia" in Vojnosanitetski pregled, 76, no. 6 (2019):607-614,
https://doi.org/10.2298/VSP170721136D . .

TY  - JOUR
AU  - Antonijević, Evica
AU  - Mandinić, Zoran
AU  - Curcić, Marijana
AU  - Đukić-Ćosić, Danijela
AU  - Milicević, Nemanja
AU  - Ivanović, Mirjana
AU  - Carević, Momir
AU  - Antonijević, Biljana
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2170
AB  - This study explores relation between dental fluorosis occurrence in schoolchildren, residents of Ritopek, a small local community near Belgrade, and fluoride exposure via drinking water. Additionally, fluoride levels were determined in children's urine and hair samples, and efforts were made to correlate them with dental fluorosis. Dental fluorosis and caries prevalence were examined in a total of 52 schoolchildren aged 7-15 years (29 boys and 23 girls). Fluoride levels in three types of samples were analyzed using composite fluoride ion-selective electrode. Results showed high prevalence of dental fluorosis (34.6 %) and low prevalence of dental caries (23.1 %, mean DMFT 0.96) among children exposed to wide range of water fluoride levels (0.11-4.14 mg/L, n = 27). About 11 % of water samples exceeded 1.5 mg/L, a drinking-water quality guideline value for fluoride given by the World Health Organization (2006). Fluoride levels in urine and hair samples ranged between 0.07-2.59 (n = 48) and 1.07-19.83 mg/L (n = 33), respectively. Severity of dental fluorosis was positively and linearly correlated with fluoride levels in drinking water (r = 0.79). Fluoride levels in urine and hair were strongly and positively correlated with levels in drinking water (r = 0.92 and 0.94, respectively). Fluoride levels in hair samples appeared to be a potentially promising biomarker of fluoride intake via drinking water on one hand, and severity of dental fluorosis on the other hand. Based on community fluorosis index value of 0.58, dental fluorosis revealed in Ritopek can be considered as "borderline" public health issue.
PB  - Springer, Dordrecht
T2  - Environmental Geochemistry & Health
T1  - 'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren
VL  - 38
IS  - 3
SP  - 885
EP  - 896
DO  - 10.1007/s10653-015-9769-x
ER  - 

@article{
author = "Antonijević, Evica and Mandinić, Zoran and Curcić, Marijana and Đukić-Ćosić, Danijela and Milicević, Nemanja and Ivanović, Mirjana and Carević, Momir and Antonijević, Biljana",
year = "2016",
abstract = "This study explores relation between dental fluorosis occurrence in schoolchildren, residents of Ritopek, a small local community near Belgrade, and fluoride exposure via drinking water. Additionally, fluoride levels were determined in children's urine and hair samples, and efforts were made to correlate them with dental fluorosis. Dental fluorosis and caries prevalence were examined in a total of 52 schoolchildren aged 7-15 years (29 boys and 23 girls). Fluoride levels in three types of samples were analyzed using composite fluoride ion-selective electrode. Results showed high prevalence of dental fluorosis (34.6 %) and low prevalence of dental caries (23.1 %, mean DMFT 0.96) among children exposed to wide range of water fluoride levels (0.11-4.14 mg/L, n = 27). About 11 % of water samples exceeded 1.5 mg/L, a drinking-water quality guideline value for fluoride given by the World Health Organization (2006). Fluoride levels in urine and hair samples ranged between 0.07-2.59 (n = 48) and 1.07-19.83 mg/L (n = 33), respectively. Severity of dental fluorosis was positively and linearly correlated with fluoride levels in drinking water (r = 0.79). Fluoride levels in urine and hair were strongly and positively correlated with levels in drinking water (r = 0.92 and 0.94, respectively). Fluoride levels in hair samples appeared to be a potentially promising biomarker of fluoride intake via drinking water on one hand, and severity of dental fluorosis on the other hand. Based on community fluorosis index value of 0.58, dental fluorosis revealed in Ritopek can be considered as "borderline" public health issue.",
publisher = "Springer, Dordrecht",
journal = "Environmental Geochemistry & Health",
title = "'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren",
volume = "38",
number = "3",
pages = "885-896",
doi = "10.1007/s10653-015-9769-x"
}

Antonijević, E., Mandinić, Z., Curcić, M., Đukić-Ćosić, D., Milicević, N., Ivanović, M., Carević, M.,& Antonijević, B.. (2016). 'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren. in Environmental Geochemistry & Health
Springer, Dordrecht., 38(3), 885-896.
https://doi.org/10.1007/s10653-015-9769-x

Antonijević E, Mandinić Z, Curcić M, Đukić-Ćosić D, Milicević N, Ivanović M, Carević M, Antonijević B. 'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren. in Environmental Geochemistry & Health. 2016;38(3):885-896.
doi:10.1007/s10653-015-9769-x .

Antonijević, Evica, Mandinić, Zoran, Curcić, Marijana, Đukić-Ćosić, Danijela, Milicević, Nemanja, Ivanović, Mirjana, Carević, Momir, Antonijević, Biljana, "'Borderline' fluorotic region in Serbia: correlations among fluoride in drinking water, biomarkers of exposure and dental fluorosis in schoolchildren" in Environmental Geochemistry & Health, 38, no. 3 (2016):885-896,
https://doi.org/10.1007/s10653-015-9769-x . .