TY  - JOUR
AU  - Marković, Aleksa
AU  - Mišić, Tijana
AU  - Calvo Guirado, Jose Luis
AU  - Delgado-Ruiz, Rafael
AU  - Janjić, Bojan
AU  - Abboud, Marcus
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2126
AB  - Purpose: To evaluate stability and success rate of hydrophilic nanostructured implants placed via osteotome sinus floor elevation (OSFE) without grafting material or using beta-tricalcium phosphate (beta-TCP), deproteinized bovine bone (DBB), or their combination, and also to assess three-dimensional volumetric stability of endo-sinus bone gained in the aforementioned conditions. Materials and Methods: OSFE with simultaneous implant placement (10-mm long SLActive-BL (R), Straumann, Basel, Switzerland) was performed. Grafting materials were randomly allocated to implant sites, whereas one site was left without graft. Implant stability was measured by resonance frequency analysis over 6 months. Implant success was evaluated after 2 years of loading. Volume of new endo-sinus bone was calculated from CBCT images using 3D Slicer (R) software. Results: A total of 180 implants were inserted into posterior maxilla of 45 patients with 6.59 +/- 0.45 mm of residual bone height, and all remained successful after 2 years. Implant stability steadily increased during healing, without significant difference between groups (p =.658). After 2 years, endo-sinus bone significantly shrank (p  lt .001) in all groups (DBB: 66.34%; beta-TCP: 61.44%; new bone formed from coagulum: 53.02%; beta-TCP + DBB: 33.47%). Conclusions: Endo-sinus bone gained after OSFE inevitably and significantly shrinks regardless of whether grafting material is applied or not. Grafting material offers no significant advantage to stability nor clinical success of hydrophilic and nanostructured implants placed simultaneously with OSFE.
PB  - Wiley, Hoboken
T2  - Clinical Implant Dentistry & Related Research
T1  - Two-Center Prospective, Randomized, Clinical, and Radiographic Study Comparing Osteotome Sinus Floor Elevation with or without Bone Graft and Simultaneous Implant Placement
VL  - 18
IS  - 5
SP  - 873
EP  - 882
DO  - 10.1111/cid.12373
ER  - 

@article{
author = "Marković, Aleksa and Mišić, Tijana and Calvo Guirado, Jose Luis and Delgado-Ruiz, Rafael and Janjić, Bojan and Abboud, Marcus",
year = "2016",
abstract = "Purpose: To evaluate stability and success rate of hydrophilic nanostructured implants placed via osteotome sinus floor elevation (OSFE) without grafting material or using beta-tricalcium phosphate (beta-TCP), deproteinized bovine bone (DBB), or their combination, and also to assess three-dimensional volumetric stability of endo-sinus bone gained in the aforementioned conditions. Materials and Methods: OSFE with simultaneous implant placement (10-mm long SLActive-BL (R), Straumann, Basel, Switzerland) was performed. Grafting materials were randomly allocated to implant sites, whereas one site was left without graft. Implant stability was measured by resonance frequency analysis over 6 months. Implant success was evaluated after 2 years of loading. Volume of new endo-sinus bone was calculated from CBCT images using 3D Slicer (R) software. Results: A total of 180 implants were inserted into posterior maxilla of 45 patients with 6.59 +/- 0.45 mm of residual bone height, and all remained successful after 2 years. Implant stability steadily increased during healing, without significant difference between groups (p =.658). After 2 years, endo-sinus bone significantly shrank (p  lt .001) in all groups (DBB: 66.34%; beta-TCP: 61.44%; new bone formed from coagulum: 53.02%; beta-TCP + DBB: 33.47%). Conclusions: Endo-sinus bone gained after OSFE inevitably and significantly shrinks regardless of whether grafting material is applied or not. Grafting material offers no significant advantage to stability nor clinical success of hydrophilic and nanostructured implants placed simultaneously with OSFE.",
publisher = "Wiley, Hoboken",
journal = "Clinical Implant Dentistry & Related Research",
title = "Two-Center Prospective, Randomized, Clinical, and Radiographic Study Comparing Osteotome Sinus Floor Elevation with or without Bone Graft and Simultaneous Implant Placement",
volume = "18",
number = "5",
pages = "873-882",
doi = "10.1111/cid.12373"
}

Marković, A., Mišić, T., Calvo Guirado, J. L., Delgado-Ruiz, R., Janjić, B.,& Abboud, M.. (2016). Two-Center Prospective, Randomized, Clinical, and Radiographic Study Comparing Osteotome Sinus Floor Elevation with or without Bone Graft and Simultaneous Implant Placement. in Clinical Implant Dentistry & Related Research
Wiley, Hoboken., 18(5), 873-882.
https://doi.org/10.1111/cid.12373

Marković A, Mišić T, Calvo Guirado JL, Delgado-Ruiz R, Janjić B, Abboud M. Two-Center Prospective, Randomized, Clinical, and Radiographic Study Comparing Osteotome Sinus Floor Elevation with or without Bone Graft and Simultaneous Implant Placement. in Clinical Implant Dentistry & Related Research. 2016;18(5):873-882.
doi:10.1111/cid.12373 .

Marković, Aleksa, Mišić, Tijana, Calvo Guirado, Jose Luis, Delgado-Ruiz, Rafael, Janjić, Bojan, Abboud, Marcus, "Two-Center Prospective, Randomized, Clinical, and Radiographic Study Comparing Osteotome Sinus Floor Elevation with or without Bone Graft and Simultaneous Implant Placement" in Clinical Implant Dentistry & Related Research, 18, no. 5 (2016):873-882,
https://doi.org/10.1111/cid.12373 . .

TY  - JOUR
AU  - Marković, Aleksa
AU  - Lazić, Zoran
AU  - Mišić, Tijana
AU  - Šćepanović, Miodrag
AU  - Todorović, Aleksandar
AU  - Thakare, Kaustubh
AU  - Janjić, Bojan
AU  - Vlahović, Zoran
AU  - Glišić, Mirko
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2081
AB  - Background/Aim. During drilling implant sites, mechanical energy is converted into thermal one resulting in transient rise in temperature of surrounding bone. The temperature of 47°C exeeding one minute impairs osseointegration, compromises mechanical properties of the local bone and could cause early implant failure. This in vitro study aimed to assess the effect of surgical drill guide and temperature of irrigans on thermal changes of the local bone during drilling implant sites, and to test the influence of irrigans temperature on the temperature of surgical drill guide. Methods. A total of 48 specimens obtained from bovine ribs were randomly allocated to four experimental conditions according to the 2 x 2 factorial design: drill guide (with or without) and saline (at 25°C or 5°C). Real-time infrared thermography was used as a method for temperature measurement. The primary outcome was bone temperature change during drilling implant sites measured at 3 osteotomy depths, whereas the second one was change in the temperature of the drill guide. Data were analyzed by Brunner and Langer nonparametric analysis and Wilcoxon test. Results. The effect of drill guide on the changes of bone temperature was significant at the entrance of osteotomy, whereas the effect of saline temperature was significant at all osteotomy levels (p  lt  0.001). No significant interaction was found (p > 0.05). Guided surgery and irrigation with saline at 25°C were associated with the highest bone temperature increase. Increase in drill guide temperature was significantly higher when saline at 25°C was used (p  lt  0.001). Conclusion. Guided implant site preparation generates higher temperature of the local bone than conventional drilling, not exceeding the threshold for thermal bone necrosis. Although saline at room temperature provides sufficient heat control during drilling, cooled saline is more effective regardless the use of surgical drill guide.
AB  - Uvod/Cilj. Tokom preparacije ležišta za implantat mehanička energija pretvara se u toplotnu, što dovodi do prolaznog povišenja temperature okolne kosti. Temperatura od 47°C tokom više od jednog minuta narušava oseointegraciju, mehaničke osobine lokalne kosti i može dovesti do ranog neuspeha implantata. Cilj ove in vitro studije bio je da se ispita uticaj hirurškog stenta i temperature irigansa na termičke promene u kosti tokom preparacije ležišta za implantat, kao i uticaj temperature irigansa na temperaturu hirurškog stenta. Metode. Ukupno 48 uzoraka dobijenih od goveđih rebara bilo je podeljeno metodom slučajnog izbora u četiri grupe prema 2 x 2 faktorskom dizajnu: prisustvo hirurškog stenta (da/ne) i temperatura fiziološkog rastvora (25°C/5°C). Temperatura je merena infracrvenom termografijom u realnom vremenu. Primarni ishod bio je promena temperature kosti tokom preparacije ležišta implantata merena na tri dubine ležišta, a sekundarni ishod promena temperature hirurškog stenta. Podaci su analizirani Bruner-Langer neparametrijskom analizom i Vilkoksonovim testom. Rezultati. Uticaj hirurškog stenta na promenutemperature kosti bio je značajan na ulazu u ležište za implantat, dok je uticaj temperature irigansa bio značajan na svim dubinama ležišta (p  lt  0,001). Međusobni uticaj ispitivanih faktora nije bio značajan (p > 0,05). Upotreba hirurškog stenta i ispiranje fiziološkim rastvorom temperature 25°C bili su praćeni najvišim porastom temperature kosti. Porast temperature hirurškog stenta bio je značajno viši kada je korišćeno ispiranje na temperaturi od 25°C (p  lt  0,001). Zaključak. Tokom kontrolisane preparacije ležišta za implantat došlo je do većeg zagrevanja kosti u poređenju sa standardnom preparacijom, ne premašujući temperaturu kritičnu za termičku nekrozu kosti. Iako ispiranje na sobnoj temperaturi obezbeđuje dovoljno hlađenja kosti tokom preparacije ležišta za implantat, ohlađeni rastvor za ispiranje je efikasniji bez obzira na primenu hirurškog stenta.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Effect of surgical drill guide and irrigans temperature on thermal bone changes during drilling implant sites: Thermographic analysis on bovine ribs
T1  - Uticaj hirurškog stenta i temperature irigansa na termičke promene u kosti tokom preparacije ležišta implantata - termografska analiza na goveđim rebrima
VL  - 73
IS  - 8
SP  - 744
EP  - 750
DO  - 10.2298/VSP141208041M
ER  - 

@article{
author = "Marković, Aleksa and Lazić, Zoran and Mišić, Tijana and Šćepanović, Miodrag and Todorović, Aleksandar and Thakare, Kaustubh and Janjić, Bojan and Vlahović, Zoran and Glišić, Mirko",
year = "2016",
abstract = "Background/Aim. During drilling implant sites, mechanical energy is converted into thermal one resulting in transient rise in temperature of surrounding bone. The temperature of 47°C exeeding one minute impairs osseointegration, compromises mechanical properties of the local bone and could cause early implant failure. This in vitro study aimed to assess the effect of surgical drill guide and temperature of irrigans on thermal changes of the local bone during drilling implant sites, and to test the influence of irrigans temperature on the temperature of surgical drill guide. Methods. A total of 48 specimens obtained from bovine ribs were randomly allocated to four experimental conditions according to the 2 x 2 factorial design: drill guide (with or without) and saline (at 25°C or 5°C). Real-time infrared thermography was used as a method for temperature measurement. The primary outcome was bone temperature change during drilling implant sites measured at 3 osteotomy depths, whereas the second one was change in the temperature of the drill guide. Data were analyzed by Brunner and Langer nonparametric analysis and Wilcoxon test. Results. The effect of drill guide on the changes of bone temperature was significant at the entrance of osteotomy, whereas the effect of saline temperature was significant at all osteotomy levels (p  lt  0.001). No significant interaction was found (p > 0.05). Guided surgery and irrigation with saline at 25°C were associated with the highest bone temperature increase. Increase in drill guide temperature was significantly higher when saline at 25°C was used (p  lt  0.001). Conclusion. Guided implant site preparation generates higher temperature of the local bone than conventional drilling, not exceeding the threshold for thermal bone necrosis. Although saline at room temperature provides sufficient heat control during drilling, cooled saline is more effective regardless the use of surgical drill guide., Uvod/Cilj. Tokom preparacije ležišta za implantat mehanička energija pretvara se u toplotnu, što dovodi do prolaznog povišenja temperature okolne kosti. Temperatura od 47°C tokom više od jednog minuta narušava oseointegraciju, mehaničke osobine lokalne kosti i može dovesti do ranog neuspeha implantata. Cilj ove in vitro studije bio je da se ispita uticaj hirurškog stenta i temperature irigansa na termičke promene u kosti tokom preparacije ležišta za implantat, kao i uticaj temperature irigansa na temperaturu hirurškog stenta. Metode. Ukupno 48 uzoraka dobijenih od goveđih rebara bilo je podeljeno metodom slučajnog izbora u četiri grupe prema 2 x 2 faktorskom dizajnu: prisustvo hirurškog stenta (da/ne) i temperatura fiziološkog rastvora (25°C/5°C). Temperatura je merena infracrvenom termografijom u realnom vremenu. Primarni ishod bio je promena temperature kosti tokom preparacije ležišta implantata merena na tri dubine ležišta, a sekundarni ishod promena temperature hirurškog stenta. Podaci su analizirani Bruner-Langer neparametrijskom analizom i Vilkoksonovim testom. Rezultati. Uticaj hirurškog stenta na promenutemperature kosti bio je značajan na ulazu u ležište za implantat, dok je uticaj temperature irigansa bio značajan na svim dubinama ležišta (p  lt  0,001). Međusobni uticaj ispitivanih faktora nije bio značajan (p > 0,05). Upotreba hirurškog stenta i ispiranje fiziološkim rastvorom temperature 25°C bili su praćeni najvišim porastom temperature kosti. Porast temperature hirurškog stenta bio je značajno viši kada je korišćeno ispiranje na temperaturi od 25°C (p  lt  0,001). Zaključak. Tokom kontrolisane preparacije ležišta za implantat došlo je do većeg zagrevanja kosti u poređenju sa standardnom preparacijom, ne premašujući temperaturu kritičnu za termičku nekrozu kosti. Iako ispiranje na sobnoj temperaturi obezbeđuje dovoljno hlađenja kosti tokom preparacije ležišta za implantat, ohlađeni rastvor za ispiranje je efikasniji bez obzira na primenu hirurškog stenta.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Effect of surgical drill guide and irrigans temperature on thermal bone changes during drilling implant sites: Thermographic analysis on bovine ribs, Uticaj hirurškog stenta i temperature irigansa na termičke promene u kosti tokom preparacije ležišta implantata - termografska analiza na goveđim rebrima",
volume = "73",
number = "8",
pages = "744-750",
doi = "10.2298/VSP141208041M"
}

Marković, A., Lazić, Z., Mišić, T., Šćepanović, M., Todorović, A., Thakare, K., Janjić, B., Vlahović, Z.,& Glišić, M.. (2016). Effect of surgical drill guide and irrigans temperature on thermal bone changes during drilling implant sites: Thermographic analysis on bovine ribs. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 73(8), 744-750.
https://doi.org/10.2298/VSP141208041M

Marković A, Lazić Z, Mišić T, Šćepanović M, Todorović A, Thakare K, Janjić B, Vlahović Z, Glišić M. Effect of surgical drill guide and irrigans temperature on thermal bone changes during drilling implant sites: Thermographic analysis on bovine ribs. in Vojnosanitetski pregled. 2016;73(8):744-750.
doi:10.2298/VSP141208041M .

Marković, Aleksa, Lazić, Zoran, Mišić, Tijana, Šćepanović, Miodrag, Todorović, Aleksandar, Thakare, Kaustubh, Janjić, Bojan, Vlahović, Zoran, Glišić, Mirko, "Effect of surgical drill guide and irrigans temperature on thermal bone changes during drilling implant sites: Thermographic analysis on bovine ribs" in Vojnosanitetski pregled, 73, no. 8 (2016):744-750,
https://doi.org/10.2298/VSP141208041M . .

TY  - JOUR
AU  - Marković, Aleksa
AU  - Mišić, Tijana
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2070
AB  - Implant placement in the esthetic zone is a complex procedure and requires a restoration-driven approach. Proper selection of patients and implant together with individual assessment of the risk of esthetic complications are very important. Correct 3D-implant positioning and sufficient bone volume should provide long-term esthetic and function. Esthetic region is a zone in which expectations and possibilities collide. Clinician should bring the important decision on the appropriate time of implant placement. Immediate implant placement is particularly challenging in the esthetic zone. Patient desire for reduced treatment time should be weighed against the possible risk factors. Protocol of immediate implant placement in conditions of unfavourable gingival biotypes, the lack of bone or soft tissue in patients with a high smile line lead to esthetic failure which is very important in the esthetic region.
PB  - Udruženje stomatologa Balkana
T2  - Balkan Journal of Dental Medicine
T1  - Implant therapy in the esthetic zone-surgical considerations
VL  - 20
IS  - 2
SP  - 83
EP  - 88
DO  - 10.1515/bjdm-2016-0013
ER  - 

@article{
author = "Marković, Aleksa and Mišić, Tijana",
year = "2016",
abstract = "Implant placement in the esthetic zone is a complex procedure and requires a restoration-driven approach. Proper selection of patients and implant together with individual assessment of the risk of esthetic complications are very important. Correct 3D-implant positioning and sufficient bone volume should provide long-term esthetic and function. Esthetic region is a zone in which expectations and possibilities collide. Clinician should bring the important decision on the appropriate time of implant placement. Immediate implant placement is particularly challenging in the esthetic zone. Patient desire for reduced treatment time should be weighed against the possible risk factors. Protocol of immediate implant placement in conditions of unfavourable gingival biotypes, the lack of bone or soft tissue in patients with a high smile line lead to esthetic failure which is very important in the esthetic region.",
publisher = "Udruženje stomatologa Balkana",
journal = "Balkan Journal of Dental Medicine",
title = "Implant therapy in the esthetic zone-surgical considerations",
volume = "20",
number = "2",
pages = "83-88",
doi = "10.1515/bjdm-2016-0013"
}

Marković, A.,& Mišić, T.. (2016). Implant therapy in the esthetic zone-surgical considerations. in Balkan Journal of Dental Medicine
Udruženje stomatologa Balkana., 20(2), 83-88.
https://doi.org/10.1515/bjdm-2016-0013

Marković A, Mišić T. Implant therapy in the esthetic zone-surgical considerations. in Balkan Journal of Dental Medicine. 2016;20(2):83-88.
doi:10.1515/bjdm-2016-0013 .

Marković, Aleksa, Mišić, Tijana, "Implant therapy in the esthetic zone-surgical considerations" in Balkan Journal of Dental Medicine, 20, no. 2 (2016):83-88,
https://doi.org/10.1515/bjdm-2016-0013 . .

TY  - JOUR
AU  - Marković, Aleksa
AU  - Čolić, Snježana
AU  - Šćepanović, Miodrag
AU  - Mišić, Tijana
AU  - Đinić, Ana
AU  - Bhusal, Dinesh Sharma
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2014
AB  - PurposesThe primary aim of the study was to investigate a 1-year success rate of early-loaded bone level implants with a chemically modified sand-blasted, large grit, acid-etched surface (SLActive (R), Institut Straumann AG, Basel, Switzerland) in the posterior maxilla. Secondary objectives included stability of these implants and peri-implant bone level. Materials and MethodsBone level (R) implants (Institut Straumann AG) inserted into premolar and/or molar maxillary sites were loaded after 6 weeks of healing. The implants were monitored for 1 year using the following outcome measures: implant success, primary and secondary stability, and peri-implant bone level. ResultsOut of 37 implants placed in 13 patients, 36 reached sufficient stability and were early loaded, whereas one underwent a delayed loading protocol. One-year success rate of early-loaded implants was 100%. Implant stability at baseline was 71.75. 6 to be steadily increased thereafter up to 1 year (80.3 +/- 3.3), except at 2 weeks when a nonsignificant decrease was noticed (71.9 +/- 3.9). Continuous and significant bone loss was observed, reaching 0.4 +/- 0.1mm in the first postoperative year. ConclusionBone level implants with the SLActive surface placed into low-density bone and loaded after 6 weeks of healing can predictably achieve and maintain a successful tissue integration.
PB  - Wiley-Blackwell, Hoboken
T2  - Clinical Implant Dentistry & Related Research
T1  - A 1-Year Prospective Clinical and Radiographic Study of Early-Loaded Bone Level Implants in the Posterior Maxilla
VL  - 17
IS  - 5
SP  - 1004
EP  - 1013
DO  - 10.1111/cid.12201
ER  - 

@article{
author = "Marković, Aleksa and Čolić, Snježana and Šćepanović, Miodrag and Mišić, Tijana and Đinić, Ana and Bhusal, Dinesh Sharma",
year = "2015",
abstract = "PurposesThe primary aim of the study was to investigate a 1-year success rate of early-loaded bone level implants with a chemically modified sand-blasted, large grit, acid-etched surface (SLActive (R), Institut Straumann AG, Basel, Switzerland) in the posterior maxilla. Secondary objectives included stability of these implants and peri-implant bone level. Materials and MethodsBone level (R) implants (Institut Straumann AG) inserted into premolar and/or molar maxillary sites were loaded after 6 weeks of healing. The implants were monitored for 1 year using the following outcome measures: implant success, primary and secondary stability, and peri-implant bone level. ResultsOut of 37 implants placed in 13 patients, 36 reached sufficient stability and were early loaded, whereas one underwent a delayed loading protocol. One-year success rate of early-loaded implants was 100%. Implant stability at baseline was 71.75. 6 to be steadily increased thereafter up to 1 year (80.3 +/- 3.3), except at 2 weeks when a nonsignificant decrease was noticed (71.9 +/- 3.9). Continuous and significant bone loss was observed, reaching 0.4 +/- 0.1mm in the first postoperative year. ConclusionBone level implants with the SLActive surface placed into low-density bone and loaded after 6 weeks of healing can predictably achieve and maintain a successful tissue integration.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Clinical Implant Dentistry & Related Research",
title = "A 1-Year Prospective Clinical and Radiographic Study of Early-Loaded Bone Level Implants in the Posterior Maxilla",
volume = "17",
number = "5",
pages = "1004-1013",
doi = "10.1111/cid.12201"
}

Marković, A., Čolić, S., Šćepanović, M., Mišić, T., Đinić, A.,& Bhusal, D. S.. (2015). A 1-Year Prospective Clinical and Radiographic Study of Early-Loaded Bone Level Implants in the Posterior Maxilla. in Clinical Implant Dentistry & Related Research
Wiley-Blackwell, Hoboken., 17(5), 1004-1013.
https://doi.org/10.1111/cid.12201

Marković A, Čolić S, Šćepanović M, Mišić T, Đinić A, Bhusal DS. A 1-Year Prospective Clinical and Radiographic Study of Early-Loaded Bone Level Implants in the Posterior Maxilla. in Clinical Implant Dentistry & Related Research. 2015;17(5):1004-1013.
doi:10.1111/cid.12201 .

Marković, Aleksa, Čolić, Snježana, Šćepanović, Miodrag, Mišić, Tijana, Đinić, Ana, Bhusal, Dinesh Sharma, "A 1-Year Prospective Clinical and Radiographic Study of Early-Loaded Bone Level Implants in the Posterior Maxilla" in Clinical Implant Dentistry & Related Research, 17, no. 5 (2015):1004-1013,
https://doi.org/10.1111/cid.12201 . .

TY  - JOUR
AU  - Šćepanović, Miodrag
AU  - Todorović, Aleksandar
AU  - Marković, Aleksa
AU  - Patrnogić, Vesna
AU  - Miličić, Biljana
AU  - Moufti, Adel M.
AU  - Mišić, Tijana
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2048
AB  - Aim: This 1-year cohort study investigated stability and pen-implant marginal bone level of immediately loaded mini dental implants used to retain overdentures. Materials and methods: Each of 30 edentulous patients received 4 mini dental implants (1.8 mm x 13 mm) in the interforaminal mandibular region. The implants were immediately loaded with pre-made overdentures. Outcome measures included implant stability and bone resorption. Implant stability was measured using the Periotest Classic (R) device immediately after placement and on the 3rd and 6th weeks and the 4th, 6th and 12th months postoperatively. The pen-implant marginal bone level (PIBL) was evaluated at the implant's mesial and distal sides from the polished platform to the marginal crest. Radiographs were taken using a tailored film holder to reproducibly position the X-ray tube at the 6th week, 4th and 12th months postoperatively. Results: The primary stability (Periotest value, PTV) measured -0.27 +/- 3.41 on a scale of -8 to + 50 (lower PTV reflects higher stability). The secondary stability decreased significantly until week 6 (mean PTV = 7.61 +/- 7.05) then increased significantly reaching (PTV = 6.17 +/- 6.15) at 12 months. The mean PIBL measured 0.40 mm after 1 year of functional loading, with no statistically significant differences at the various follow-ups (p = 0.218). Conclusions: Mini dental implants placed into the interforaminal region could achieve a favorable primary stability for immediate loading. The follow-up Periotest values fluctuated, apparently reflecting the dynamics of bone remodeling, with the implants remaining clinically stable (98.3%) after 1 year of function. The 1-year bone resorption around immediately loaded MDIs is within the clinically acceptable range for standard implants.
PB  - Elsevier Gmbh, Urban & Fischer Verlag, Jena
T2  - Annals of Anatomy - Anatomischer Anzeiger
T1  - Immediately loaded mini dental implants as overdenture retainers: 1-Year cohort study of implant stability and peri-implant marginal bone level
VL  - 199
SP  - 85
EP  - 91
DO  - 10.1016/j.aanat.2013.12.005
ER  - 

@article{
author = "Šćepanović, Miodrag and Todorović, Aleksandar and Marković, Aleksa and Patrnogić, Vesna and Miličić, Biljana and Moufti, Adel M. and Mišić, Tijana",
year = "2015",
abstract = "Aim: This 1-year cohort study investigated stability and pen-implant marginal bone level of immediately loaded mini dental implants used to retain overdentures. Materials and methods: Each of 30 edentulous patients received 4 mini dental implants (1.8 mm x 13 mm) in the interforaminal mandibular region. The implants were immediately loaded with pre-made overdentures. Outcome measures included implant stability and bone resorption. Implant stability was measured using the Periotest Classic (R) device immediately after placement and on the 3rd and 6th weeks and the 4th, 6th and 12th months postoperatively. The pen-implant marginal bone level (PIBL) was evaluated at the implant's mesial and distal sides from the polished platform to the marginal crest. Radiographs were taken using a tailored film holder to reproducibly position the X-ray tube at the 6th week, 4th and 12th months postoperatively. Results: The primary stability (Periotest value, PTV) measured -0.27 +/- 3.41 on a scale of -8 to + 50 (lower PTV reflects higher stability). The secondary stability decreased significantly until week 6 (mean PTV = 7.61 +/- 7.05) then increased significantly reaching (PTV = 6.17 +/- 6.15) at 12 months. The mean PIBL measured 0.40 mm after 1 year of functional loading, with no statistically significant differences at the various follow-ups (p = 0.218). Conclusions: Mini dental implants placed into the interforaminal region could achieve a favorable primary stability for immediate loading. The follow-up Periotest values fluctuated, apparently reflecting the dynamics of bone remodeling, with the implants remaining clinically stable (98.3%) after 1 year of function. The 1-year bone resorption around immediately loaded MDIs is within the clinically acceptable range for standard implants.",
publisher = "Elsevier Gmbh, Urban & Fischer Verlag, Jena",
journal = "Annals of Anatomy - Anatomischer Anzeiger",
title = "Immediately loaded mini dental implants as overdenture retainers: 1-Year cohort study of implant stability and peri-implant marginal bone level",
volume = "199",
pages = "85-91",
doi = "10.1016/j.aanat.2013.12.005"
}

Šćepanović, M., Todorović, A., Marković, A., Patrnogić, V., Miličić, B., Moufti, A. M.,& Mišić, T.. (2015). Immediately loaded mini dental implants as overdenture retainers: 1-Year cohort study of implant stability and peri-implant marginal bone level. in Annals of Anatomy - Anatomischer Anzeiger
Elsevier Gmbh, Urban & Fischer Verlag, Jena., 199, 85-91.
https://doi.org/10.1016/j.aanat.2013.12.005

Šćepanović M, Todorović A, Marković A, Patrnogić V, Miličić B, Moufti AM, Mišić T. Immediately loaded mini dental implants as overdenture retainers: 1-Year cohort study of implant stability and peri-implant marginal bone level. in Annals of Anatomy - Anatomischer Anzeiger. 2015;199:85-91.
doi:10.1016/j.aanat.2013.12.005 .

Šćepanović, Miodrag, Todorović, Aleksandar, Marković, Aleksa, Patrnogić, Vesna, Miličić, Biljana, Moufti, Adel M., Mišić, Tijana, "Immediately loaded mini dental implants as overdenture retainers: 1-Year cohort study of implant stability and peri-implant marginal bone level" in Annals of Anatomy - Anatomischer Anzeiger, 199 (2015):85-91,
https://doi.org/10.1016/j.aanat.2013.12.005 . .

TY  - JOUR
AU  - Lazić, Zoran
AU  - Golubović, Mileta
AU  - Marković, Aleksa
AU  - Šćepanović, Miodrag
AU  - Mišić, Tijana
AU  - Vlahović, Zoran
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1964
AB  - AimThe aim of this experimental study is to compare the effect of mini-incision flapless versus flap technique of implant placement on the amount of vascular structures and blood vessel elements in peri-implant soft tissue, using immunohistochemical analysis. MethodThe experiment was conducted on five domestic pigs. Each animal received six implants in mandible according to the split-mouth design. On one randomly chosen jaw side, mini-incision flapless surgery was performed, whereas on the opposite jaw side, flap was raised. After 3months of implant healing through submerged approach, the experimental animals were sacrificed and samples for immunohistochemical analyses were taken from the buccal side of peri-implant mucosa next to the neck of implants, from three levels. The study outcome was the presence of vascular structures and elements of the blood vessels in the peri-implant mucosa per microscopic field, estimated through ordinal scores from 0 to 2. Effects of surgical approach, site of implantation, and their interaction on vascular scores of peri-implant mucosa were assessed by Brunner and Langer nonparametric analysis of longitudinal data. ResultsStatistically significant effect of surgical approach on vascularity of peri-implant mucosa has been revealed in the second mucosal layer, where flapless approach provided higher vascularity compared with flap approach (P=0.002). In the remaining two layers, surgical approach did not affect mucosal vascularity significantly (layer 1: P=0.071; layer 3: P=0.433). ConclusionThe flapless surgical implant placement approach using mini-incision provides better vascularization of peri-implant mucosa after 3months of healing compared with flap surgery.
PB  - Wiley-Blackwell, Hoboken
T2  - Clinical Oral Implants Research
T1  - Immunohistochemical analysis of blood vessels in peri-implant mucosa: a comparison between mini-incision flapless and flap surgeries in domestic pigs
VL  - 26
IS  - 7
SP  - 775
EP  - 779
DO  - 10.1111/clr.12337
ER  - 

@article{
author = "Lazić, Zoran and Golubović, Mileta and Marković, Aleksa and Šćepanović, Miodrag and Mišić, Tijana and Vlahović, Zoran",
year = "2015",
abstract = "AimThe aim of this experimental study is to compare the effect of mini-incision flapless versus flap technique of implant placement on the amount of vascular structures and blood vessel elements in peri-implant soft tissue, using immunohistochemical analysis. MethodThe experiment was conducted on five domestic pigs. Each animal received six implants in mandible according to the split-mouth design. On one randomly chosen jaw side, mini-incision flapless surgery was performed, whereas on the opposite jaw side, flap was raised. After 3months of implant healing through submerged approach, the experimental animals were sacrificed and samples for immunohistochemical analyses were taken from the buccal side of peri-implant mucosa next to the neck of implants, from three levels. The study outcome was the presence of vascular structures and elements of the blood vessels in the peri-implant mucosa per microscopic field, estimated through ordinal scores from 0 to 2. Effects of surgical approach, site of implantation, and their interaction on vascular scores of peri-implant mucosa were assessed by Brunner and Langer nonparametric analysis of longitudinal data. ResultsStatistically significant effect of surgical approach on vascularity of peri-implant mucosa has been revealed in the second mucosal layer, where flapless approach provided higher vascularity compared with flap approach (P=0.002). In the remaining two layers, surgical approach did not affect mucosal vascularity significantly (layer 1: P=0.071; layer 3: P=0.433). ConclusionThe flapless surgical implant placement approach using mini-incision provides better vascularization of peri-implant mucosa after 3months of healing compared with flap surgery.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Clinical Oral Implants Research",
title = "Immunohistochemical analysis of blood vessels in peri-implant mucosa: a comparison between mini-incision flapless and flap surgeries in domestic pigs",
volume = "26",
number = "7",
pages = "775-779",
doi = "10.1111/clr.12337"
}

Lazić, Z., Golubović, M., Marković, A., Šćepanović, M., Mišić, T.,& Vlahović, Z.. (2015). Immunohistochemical analysis of blood vessels in peri-implant mucosa: a comparison between mini-incision flapless and flap surgeries in domestic pigs. in Clinical Oral Implants Research
Wiley-Blackwell, Hoboken., 26(7), 775-779.
https://doi.org/10.1111/clr.12337

Lazić Z, Golubović M, Marković A, Šćepanović M, Mišić T, Vlahović Z. Immunohistochemical analysis of blood vessels in peri-implant mucosa: a comparison between mini-incision flapless and flap surgeries in domestic pigs. in Clinical Oral Implants Research. 2015;26(7):775-779.
doi:10.1111/clr.12337 .

Lazić, Zoran, Golubović, Mileta, Marković, Aleksa, Šćepanović, Miodrag, Mišić, Tijana, Vlahović, Zoran, "Immunohistochemical analysis of blood vessels in peri-implant mucosa: a comparison between mini-incision flapless and flap surgeries in domestic pigs" in Clinical Oral Implants Research, 26, no. 7 (2015):775-779,
https://doi.org/10.1111/clr.12337 . .

TY  - JOUR
AU  - Marković, Aleksa
AU  - Mišić, Tijana
AU  - Mancić, Dragan
AU  - Jovanović, Igor
AU  - Šćepanović, Miodrag
AU  - Jezdić, Zoran
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1877
AB  - Objectives: To compare the effect of two surgical techniques, lateral condensation and bone drilling, on changes in temperature of the adjacent low-density bone during implant placement into posterior maxilla and to investigate the influence of the host factors - age, gender, region of implantation, bone density, and thickness of the cortical bone at the recipient sites. Material and methods: Local bone temperature was measured thermographically during implant placement into posterior maxilla following lateral bone condensing (test group) or bone drilling (controls). The main study outcomes were baseline bone temperature prior to implantation and maximum bone temperature recorded during implantation. Early implant success was evaluated after 6 months of healing. Results: A total of 40 implants were randomly allocated to test and control groups and placed into maxillary premolar and/or molar region of 18 participants of both genders and average age of 51.74 years. All recorded bone temperatures were below the threshold for thermal necrosis. Although both groups showed significant increase in bone temperature during implant placement procedure (P  lt = 0.0005), it was significantly higher for bone condensing compared with drilling (P  lt = 0.0005; 3.79 +/- 1.54 degrees C; 1.91 +/- 0.70 degrees C respectively). No host factor was singled out as a significant predictor of bone temperature changes, although trend of higher increase was observed in young patients, regardless of gender, during implant placement procedure into maxillary first premolar region with bone density type 3 and cortical layer thicker than 1 mm. Early implant success rate after 6 months follow-up was 100%. Conclusion: Although both surgical techniques, bone condensing and bone drilling, can be considered safe regarding their thermal effect on the bone of posterior maxilla, bone drilling is associated with fewer local bone heating during implantation. Host factors do not affect the bone thermal changes significantly.
PB  - Wiley, Hoboken
T2  - Clinical Oral Implants Research
T1  - Real-time thermographic analysis of low-density bone during implant placement: a randomized parallel-group clinical study comparing lateral condensation with bone drilling surgical technique
VL  - 25
IS  - 8
SP  - 910
EP  - 918
DO  - 10.1111/clr.12191
ER  - 

@article{
author = "Marković, Aleksa and Mišić, Tijana and Mancić, Dragan and Jovanović, Igor and Šćepanović, Miodrag and Jezdić, Zoran",
year = "2014",
abstract = "Objectives: To compare the effect of two surgical techniques, lateral condensation and bone drilling, on changes in temperature of the adjacent low-density bone during implant placement into posterior maxilla and to investigate the influence of the host factors - age, gender, region of implantation, bone density, and thickness of the cortical bone at the recipient sites. Material and methods: Local bone temperature was measured thermographically during implant placement into posterior maxilla following lateral bone condensing (test group) or bone drilling (controls). The main study outcomes were baseline bone temperature prior to implantation and maximum bone temperature recorded during implantation. Early implant success was evaluated after 6 months of healing. Results: A total of 40 implants were randomly allocated to test and control groups and placed into maxillary premolar and/or molar region of 18 participants of both genders and average age of 51.74 years. All recorded bone temperatures were below the threshold for thermal necrosis. Although both groups showed significant increase in bone temperature during implant placement procedure (P  lt = 0.0005), it was significantly higher for bone condensing compared with drilling (P  lt = 0.0005; 3.79 +/- 1.54 degrees C; 1.91 +/- 0.70 degrees C respectively). No host factor was singled out as a significant predictor of bone temperature changes, although trend of higher increase was observed in young patients, regardless of gender, during implant placement procedure into maxillary first premolar region with bone density type 3 and cortical layer thicker than 1 mm. Early implant success rate after 6 months follow-up was 100%. Conclusion: Although both surgical techniques, bone condensing and bone drilling, can be considered safe regarding their thermal effect on the bone of posterior maxilla, bone drilling is associated with fewer local bone heating during implantation. Host factors do not affect the bone thermal changes significantly.",
publisher = "Wiley, Hoboken",
journal = "Clinical Oral Implants Research",
title = "Real-time thermographic analysis of low-density bone during implant placement: a randomized parallel-group clinical study comparing lateral condensation with bone drilling surgical technique",
volume = "25",
number = "8",
pages = "910-918",
doi = "10.1111/clr.12191"
}

Marković, A., Mišić, T., Mancić, D., Jovanović, I., Šćepanović, M.,& Jezdić, Z.. (2014). Real-time thermographic analysis of low-density bone during implant placement: a randomized parallel-group clinical study comparing lateral condensation with bone drilling surgical technique. in Clinical Oral Implants Research
Wiley, Hoboken., 25(8), 910-918.
https://doi.org/10.1111/clr.12191

Marković A, Mišić T, Mancić D, Jovanović I, Šćepanović M, Jezdić Z. Real-time thermographic analysis of low-density bone during implant placement: a randomized parallel-group clinical study comparing lateral condensation with bone drilling surgical technique. in Clinical Oral Implants Research. 2014;25(8):910-918.
doi:10.1111/clr.12191 .

Marković, Aleksa, Mišić, Tijana, Mancić, Dragan, Jovanović, Igor, Šćepanović, Miodrag, Jezdić, Zoran, "Real-time thermographic analysis of low-density bone during implant placement: a randomized parallel-group clinical study comparing lateral condensation with bone drilling surgical technique" in Clinical Oral Implants Research, 25, no. 8 (2014):910-918,
https://doi.org/10.1111/clr.12191 . .

TY  - JOUR
AU  - Delgado-Ruiz, Rafael
AU  - Marković, Aleksa
AU  - Calvo Guirado, Jose Luis
AU  - Lazić, Zoran
AU  - Piattelli, Adriano
AU  - Boticelli, Daniele
AU  - Maté-Sánchez, José Eduardo
AU  - Negri, Bruno
AU  - Ramírez-Fernández, María Piedad
AU  - Mišić, Tijana
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1900
AB  - Background/Aim. The modification of implant surfaces could affect mechanical implant stability as well as dynamics and quality of peri-implant bone healing. The aim of this 3-month experimental study in dogs was to investigate implant stability, marginal bone levels and bone tissue response to zirconia dental implants with two laser-micro-grooved intraosseous surfaces in comparison with nongrooved sandblasted zirconia and sandblasted, high-temperature etched titanium implants. Methods. Implant surface characterization was performed using optical interferometric profilometry and energy dispersive X-ray spectroscopy. A total of 96 implants (4 mm in diameter and 10 mm in length) were inserted randomly in both sides of the lower jaw of 12 Fox Hound dogs divided into groups of 24 each: the control (titanium), the group A (sandblasted zirconia), the group B (sandblasted zirconia plus microgrooved neck) and the group C (sandblasted zirconia plus all microgrooved). All the implants were immediately loaded. Insertion torque, periotest values, radiographic crestal bone level and removal torque were recorded during the 3-month follow-up. Qualitative scanning electon microscope (SEM) analysis of the bone-implant interfaces of each group was performed. Results. Insertion torque values were higher in the group C and control implants (p  lt  0.05). Periotest values increased in all the periods in proportion to the extent of microgrooving as follows: the group C > the control > the group B > the group A (p  lt  0.05). Radiographic measurements showed minimal crestal bone loss at 3 months for microgrooved zirconia implants (groups C and B) and control implants compared with the group A implants (p  lt  0.05). The removal torque values increased with time for all the groups as follows: the group C > the control > the group B > the group A (p  lt  0.05). SEM showed that implant surfaces of the groups B and C had an extra bone growth inside the microgrooves that corresponded to the shape and direction of the microgrooves. Conclusion. The addition of microgrooves to the entire intraosseous surface of zirconia dental implants enhances primary and secondary implant stability, promotes bone tissue in growth and preserves crestal bone levels.
AB  - Uvod/Cilj. Modifikacija površine implantata može uticati na njegovu mehaničku stabilnost kao i na dinamiku i kvalitet periimplantatnog koštanog zarastanja. Cilj ove tromesečne eksperimentalne studije na psima bio je da se ispita stabilnost implantata, nivo marginalne kosti i odgovor koštanog tkiva na cirkonijum endoosealne implantate sa dve intraosealne površine mikrostrukturirane laserom u poređenju sa peskiranim cirkonijum implantatima čija površina nije mikrostrukturirana kao i sa titanijum implantatima čije su površine peskirane i nagrižene visokom temperaturom. Metode. Karakterizacija površine implantata učinjena je optičkom interferometrijskom profilometrijom i analizom energetskog spektra pri difrakciji X-zračenja. Ukupno 96 implantata (prečnika 4 mm i dužine 10 mm) ugrađeno je nasumično i obostrano u donju vilicu kod 12 pasa (lisičara) i podeljeno u četiri grupe po 24: kontrolna (titanijum implantati); grupa A (peskirani cirkonijum implantati); grupa B (peskirani cirkonijum implantati sa mikrokanalima u koronarnoj trećini); grupa C (peskirani cirkonijum implantati sa mikrokanalima duž cele površine). Svi implantati su odmah opterećeni. Meren je obrtni momenat pri ugradnji implantata, vrednosti periotesta, radiografski nivo marginalne kosti i obrtni moment za uklanjanje implantata tokom tromesečnog perioda praćenja. Međuspoj kosti i implantata iz svake grupe ispitivan je kvalitativnom skenirajućom elektronskom mikroskopijom (SEM). Rezultati. Veći obrtni momenat zabeležen je pri ugradnji implantata kod grupe C i kontrolne grupe (p  lt  0,05). U ispitivanom vremenskom periodu, vrednosti periotesta uvećavale su se srazmerno obimu mikrostrukturiranja površine i to: grupa C > kontrolna grupa > grupa B > grupa A (p  lt  0,05). Radiografskom analizom utvrđen je minimalni gubitak marginalne kosti u trećem mesecu praćenja oko cirkonijum implantata sa mikrokanalima (grupa B i C) i kontrola u poređenju sa implantatima grupe A (p  lt  0,05). Vrednosti obrtnog momenta za uklanjanje implantata vremenom su se uvećavale u svim grupama na sledeći način: grupa C > kontrolna grupa > grupa B > grupa A (p  lt  0,05). Kod implantatnih površina grupa B i C, SEM je pokazala dodatni rast koštanog tkiva unutar mikrokanala koji odgovara njihovom obliku i pravcu. Zaključak. Formiranje mikrokanala duž cele intraosealne površine cirkonijum endoosealnih implantata povećava primarnu i sekundarnu implantatnu stabilnost, podstiče urastanje koštanog tkiva i održava nivo marginalne kosti.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Implant stability and marginal bone level of microgrooved zirconia dental implants: A 3-month experimental study on dogs
T1  - Implantatna stabilnost i nivo marginalne kosti kod cirkonijum endoosealnih implantata sa mikrostrukturiranom površinom - tromesečna eksperimentalna studija na psima
VL  - 71
IS  - 5
SP  - 451
EP  - 461
DO  - 10.2298/VSP121003034D
ER  - 

@article{
author = "Delgado-Ruiz, Rafael and Marković, Aleksa and Calvo Guirado, Jose Luis and Lazić, Zoran and Piattelli, Adriano and Boticelli, Daniele and Maté-Sánchez, José Eduardo and Negri, Bruno and Ramírez-Fernández, María Piedad and Mišić, Tijana",
year = "2014",
abstract = "Background/Aim. The modification of implant surfaces could affect mechanical implant stability as well as dynamics and quality of peri-implant bone healing. The aim of this 3-month experimental study in dogs was to investigate implant stability, marginal bone levels and bone tissue response to zirconia dental implants with two laser-micro-grooved intraosseous surfaces in comparison with nongrooved sandblasted zirconia and sandblasted, high-temperature etched titanium implants. Methods. Implant surface characterization was performed using optical interferometric profilometry and energy dispersive X-ray spectroscopy. A total of 96 implants (4 mm in diameter and 10 mm in length) were inserted randomly in both sides of the lower jaw of 12 Fox Hound dogs divided into groups of 24 each: the control (titanium), the group A (sandblasted zirconia), the group B (sandblasted zirconia plus microgrooved neck) and the group C (sandblasted zirconia plus all microgrooved). All the implants were immediately loaded. Insertion torque, periotest values, radiographic crestal bone level and removal torque were recorded during the 3-month follow-up. Qualitative scanning electon microscope (SEM) analysis of the bone-implant interfaces of each group was performed. Results. Insertion torque values were higher in the group C and control implants (p  lt  0.05). Periotest values increased in all the periods in proportion to the extent of microgrooving as follows: the group C > the control > the group B > the group A (p  lt  0.05). Radiographic measurements showed minimal crestal bone loss at 3 months for microgrooved zirconia implants (groups C and B) and control implants compared with the group A implants (p  lt  0.05). The removal torque values increased with time for all the groups as follows: the group C > the control > the group B > the group A (p  lt  0.05). SEM showed that implant surfaces of the groups B and C had an extra bone growth inside the microgrooves that corresponded to the shape and direction of the microgrooves. Conclusion. The addition of microgrooves to the entire intraosseous surface of zirconia dental implants enhances primary and secondary implant stability, promotes bone tissue in growth and preserves crestal bone levels., Uvod/Cilj. Modifikacija površine implantata može uticati na njegovu mehaničku stabilnost kao i na dinamiku i kvalitet periimplantatnog koštanog zarastanja. Cilj ove tromesečne eksperimentalne studije na psima bio je da se ispita stabilnost implantata, nivo marginalne kosti i odgovor koštanog tkiva na cirkonijum endoosealne implantate sa dve intraosealne površine mikrostrukturirane laserom u poređenju sa peskiranim cirkonijum implantatima čija površina nije mikrostrukturirana kao i sa titanijum implantatima čije su površine peskirane i nagrižene visokom temperaturom. Metode. Karakterizacija površine implantata učinjena je optičkom interferometrijskom profilometrijom i analizom energetskog spektra pri difrakciji X-zračenja. Ukupno 96 implantata (prečnika 4 mm i dužine 10 mm) ugrađeno je nasumično i obostrano u donju vilicu kod 12 pasa (lisičara) i podeljeno u četiri grupe po 24: kontrolna (titanijum implantati); grupa A (peskirani cirkonijum implantati); grupa B (peskirani cirkonijum implantati sa mikrokanalima u koronarnoj trećini); grupa C (peskirani cirkonijum implantati sa mikrokanalima duž cele površine). Svi implantati su odmah opterećeni. Meren je obrtni momenat pri ugradnji implantata, vrednosti periotesta, radiografski nivo marginalne kosti i obrtni moment za uklanjanje implantata tokom tromesečnog perioda praćenja. Međuspoj kosti i implantata iz svake grupe ispitivan je kvalitativnom skenirajućom elektronskom mikroskopijom (SEM). Rezultati. Veći obrtni momenat zabeležen je pri ugradnji implantata kod grupe C i kontrolne grupe (p  lt  0,05). U ispitivanom vremenskom periodu, vrednosti periotesta uvećavale su se srazmerno obimu mikrostrukturiranja površine i to: grupa C > kontrolna grupa > grupa B > grupa A (p  lt  0,05). Radiografskom analizom utvrđen je minimalni gubitak marginalne kosti u trećem mesecu praćenja oko cirkonijum implantata sa mikrokanalima (grupa B i C) i kontrola u poređenju sa implantatima grupe A (p  lt  0,05). Vrednosti obrtnog momenta za uklanjanje implantata vremenom su se uvećavale u svim grupama na sledeći način: grupa C > kontrolna grupa > grupa B > grupa A (p  lt  0,05). Kod implantatnih površina grupa B i C, SEM je pokazala dodatni rast koštanog tkiva unutar mikrokanala koji odgovara njihovom obliku i pravcu. Zaključak. Formiranje mikrokanala duž cele intraosealne površine cirkonijum endoosealnih implantata povećava primarnu i sekundarnu implantatnu stabilnost, podstiče urastanje koštanog tkiva i održava nivo marginalne kosti.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Implant stability and marginal bone level of microgrooved zirconia dental implants: A 3-month experimental study on dogs, Implantatna stabilnost i nivo marginalne kosti kod cirkonijum endoosealnih implantata sa mikrostrukturiranom površinom - tromesečna eksperimentalna studija na psima",
volume = "71",
number = "5",
pages = "451-461",
doi = "10.2298/VSP121003034D"
}

Delgado-Ruiz, R., Marković, A., Calvo Guirado, J. L., Lazić, Z., Piattelli, A., Boticelli, D., Maté-Sánchez, J. E., Negri, B., Ramírez-Fernández, M. P.,& Mišić, T.. (2014). Implant stability and marginal bone level of microgrooved zirconia dental implants: A 3-month experimental study on dogs. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 71(5), 451-461.
https://doi.org/10.2298/VSP121003034D

Delgado-Ruiz R, Marković A, Calvo Guirado JL, Lazić Z, Piattelli A, Boticelli D, Maté-Sánchez JE, Negri B, Ramírez-Fernández MP, Mišić T. Implant stability and marginal bone level of microgrooved zirconia dental implants: A 3-month experimental study on dogs. in Vojnosanitetski pregled. 2014;71(5):451-461.
doi:10.2298/VSP121003034D .

Delgado-Ruiz, Rafael, Marković, Aleksa, Calvo Guirado, Jose Luis, Lazić, Zoran, Piattelli, Adriano, Boticelli, Daniele, Maté-Sánchez, José Eduardo, Negri, Bruno, Ramírez-Fernández, María Piedad, Mišić, Tijana, "Implant stability and marginal bone level of microgrooved zirconia dental implants: A 3-month experimental study on dogs" in Vojnosanitetski pregled, 71, no. 5 (2014):451-461,
https://doi.org/10.2298/VSP121003034D . .

TY  - JOUR
AU  - Marković, Aleksa
AU  - Mišić, Tijana
AU  - Miličić, Biljana
AU  - Calvo Guirado, Jose Luis
AU  - Aleksić, Zoran
AU  - Đinić, Ana
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1830
AB  - Objectives The study aimed to investigate the effect of surgical technique, implant macrodesign and insertion torque on bone temperature changes during implant placement. Material and methods In the in vitro study, 144 self-tapping (blueSKY (R) 4x10mm; Bredent) and 144 non-self-tapping (Standard implant (R) 4.1x10mm; Straumann) were placed in osteotomies prepared in pig ribs by lateral bone condensing or bone drilling techniques. The maximum insertion torque values of 30, 35 and 40Ncm were used. Real-time bone temperature measurement during implant placement was performed by three thermocouples positioned vertically, in tripod configuration around every osteotomy, at a distance of 5mm from it and at depths of 1, 5 and 10mm. Data were analysed using Kruskal-Wallis, Mann-Whitney U-tests and Regression analysis. Results Significant predictor of bone temperature at the osteotomy depth of 1mm was insertion torque (P=0.003) and at the depth of 10-mm implant macrodesign (P=0.029), while no significant predictor at depth of 5mm was identified (0.05). Higher insertion torque values as well as non-self-tapping implant macrodesign were related to higher temperatures. Implant placement in sites prepared by bone drilling induced significantly higher temperature increase (P=0.021) compared with bone condensing sites at the depth of 5mm, while no significant difference was recorded at other depths. Compared with 30Ncm, insertion torque values of 35 and 40Ncm produced significantly higher temperature increase (P=0.005; P=0.003, respectively) at the depth of 1mm. There was no significant difference in temperature change induced by 35 and 40Ncm, neither by implant macrodesign at all investigated depths (0.05). Conclusions Placement of self-tapping implants with low insertion torque into sites prepared by lateral bone condensing technique might be advantageous in terms of thermal effect on bone.
PB  - Wiley-Blackwell, Hoboken
T2  - Clinical Oral Implants Research
T1  - Heat generation during implant placement in low-density bone: effect of surgical technique, insertion torque and implant macro design
VL  - 24
IS  - 7
SP  - 798
EP  - 805
DO  - 10.1111/j.1600-0501.2012.02460.x
ER  - 

@article{
author = "Marković, Aleksa and Mišić, Tijana and Miličić, Biljana and Calvo Guirado, Jose Luis and Aleksić, Zoran and Đinić, Ana",
year = "2013",
abstract = "Objectives The study aimed to investigate the effect of surgical technique, implant macrodesign and insertion torque on bone temperature changes during implant placement. Material and methods In the in vitro study, 144 self-tapping (blueSKY (R) 4x10mm; Bredent) and 144 non-self-tapping (Standard implant (R) 4.1x10mm; Straumann) were placed in osteotomies prepared in pig ribs by lateral bone condensing or bone drilling techniques. The maximum insertion torque values of 30, 35 and 40Ncm were used. Real-time bone temperature measurement during implant placement was performed by three thermocouples positioned vertically, in tripod configuration around every osteotomy, at a distance of 5mm from it and at depths of 1, 5 and 10mm. Data were analysed using Kruskal-Wallis, Mann-Whitney U-tests and Regression analysis. Results Significant predictor of bone temperature at the osteotomy depth of 1mm was insertion torque (P=0.003) and at the depth of 10-mm implant macrodesign (P=0.029), while no significant predictor at depth of 5mm was identified (0.05). Higher insertion torque values as well as non-self-tapping implant macrodesign were related to higher temperatures. Implant placement in sites prepared by bone drilling induced significantly higher temperature increase (P=0.021) compared with bone condensing sites at the depth of 5mm, while no significant difference was recorded at other depths. Compared with 30Ncm, insertion torque values of 35 and 40Ncm produced significantly higher temperature increase (P=0.005; P=0.003, respectively) at the depth of 1mm. There was no significant difference in temperature change induced by 35 and 40Ncm, neither by implant macrodesign at all investigated depths (0.05). Conclusions Placement of self-tapping implants with low insertion torque into sites prepared by lateral bone condensing technique might be advantageous in terms of thermal effect on bone.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Clinical Oral Implants Research",
title = "Heat generation during implant placement in low-density bone: effect of surgical technique, insertion torque and implant macro design",
volume = "24",
number = "7",
pages = "798-805",
doi = "10.1111/j.1600-0501.2012.02460.x"
}

Marković, A., Mišić, T., Miličić, B., Calvo Guirado, J. L., Aleksić, Z.,& Đinić, A.. (2013). Heat generation during implant placement in low-density bone: effect of surgical technique, insertion torque and implant macro design. in Clinical Oral Implants Research
Wiley-Blackwell, Hoboken., 24(7), 798-805.
https://doi.org/10.1111/j.1600-0501.2012.02460.x

Marković A, Mišić T, Miličić B, Calvo Guirado JL, Aleksić Z, Đinić A. Heat generation during implant placement in low-density bone: effect of surgical technique, insertion torque and implant macro design. in Clinical Oral Implants Research. 2013;24(7):798-805.
doi:10.1111/j.1600-0501.2012.02460.x .

Marković, Aleksa, Mišić, Tijana, Miličić, Biljana, Calvo Guirado, Jose Luis, Aleksić, Zoran, Đinić, Ana, "Heat generation during implant placement in low-density bone: effect of surgical technique, insertion torque and implant macro design" in Clinical Oral Implants Research, 24, no. 7 (2013):798-805,
https://doi.org/10.1111/j.1600-0501.2012.02460.x . .

TY  - JOUR
AU  - Marković, Aleksa
AU  - Luis Calvo-Guirado, Jose
AU  - Lazić, Zoran
AU  - Gomez-Moreno, Gerardo
AU  - Ćalasan, Dejan
AU  - Guardia, Javier
AU  - Čolić, Snježana
AU  - Aguilar-Salvatierra, Antonio
AU  - Gačić, Bojan
AU  - Delgado-Ruiz, Rafael
AU  - Janjić, Bojan
AU  - Mišić, Tijana
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1816
AB  - Purpose: The aim of this study was to investigate the relationship between surgical techniques and implant macro-design (self-tapping/non-self-tapping) for the optimization of implant stability in the low-density bone present in the posterior maxilla using resonance frequency analysis (RFA). Materials and Methods: A total of 102 implants were studied. Fifty-six self-tapping BlueSkyBredent (R) (Bredent GmbH &, Senden, Germany) and 56 non-self-tapping Standard Plus Straumann (R) (Institut Straumann AG (R), Waldenburg, Switzerland) were placed in the posterior segment of the maxilla. Implants of both types were placed in sites prepared with either lateral bone-condensing or with bone-drilling techniques. Implant stability measurements were performed using RFA immediately after implant placement and weekly during a 12-week follow-up period. Results: Both types of implants placed after bone condensing achieved significantly higher stability immediately after surgery, as well as during the entire 12-week observation period compared with those placed following bone drilling. After bone condensation, there were no significant differences in primary stability or in implant stability after the first week between both implant types. From 2 to 12 postoperative weeks, significantly higher stability was shown by self-tapping implants. After bone drilling, self-tapping implants achieved significantly higher stability than non-self-tapping implants during the entire follow-up period. Conclusions: The outcomes of the present study indicate that bone drilling is not an effective technique for improving implant stability and, following this technique, the use of self-tapping implants is highly recommended. Implant stability optimization in the soft bone can be achieved by lateral bone-condensing technique, regardless of implant macro-design.
PB  - Wiley, Hoboken
T2  - Clinical Implant Dentistry & Related Research
T1  - Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study
VL  - 15
IS  - 3
SP  - 341
EP  - 349
DO  - 10.1111/j.1708-8208.2011.00415.x
ER  - 

@article{
author = "Marković, Aleksa and Luis Calvo-Guirado, Jose and Lazić, Zoran and Gomez-Moreno, Gerardo and Ćalasan, Dejan and Guardia, Javier and Čolić, Snježana and Aguilar-Salvatierra, Antonio and Gačić, Bojan and Delgado-Ruiz, Rafael and Janjić, Bojan and Mišić, Tijana",
year = "2013",
abstract = "Purpose: The aim of this study was to investigate the relationship between surgical techniques and implant macro-design (self-tapping/non-self-tapping) for the optimization of implant stability in the low-density bone present in the posterior maxilla using resonance frequency analysis (RFA). Materials and Methods: A total of 102 implants were studied. Fifty-six self-tapping BlueSkyBredent (R) (Bredent GmbH &, Senden, Germany) and 56 non-self-tapping Standard Plus Straumann (R) (Institut Straumann AG (R), Waldenburg, Switzerland) were placed in the posterior segment of the maxilla. Implants of both types were placed in sites prepared with either lateral bone-condensing or with bone-drilling techniques. Implant stability measurements were performed using RFA immediately after implant placement and weekly during a 12-week follow-up period. Results: Both types of implants placed after bone condensing achieved significantly higher stability immediately after surgery, as well as during the entire 12-week observation period compared with those placed following bone drilling. After bone condensation, there were no significant differences in primary stability or in implant stability after the first week between both implant types. From 2 to 12 postoperative weeks, significantly higher stability was shown by self-tapping implants. After bone drilling, self-tapping implants achieved significantly higher stability than non-self-tapping implants during the entire follow-up period. Conclusions: The outcomes of the present study indicate that bone drilling is not an effective technique for improving implant stability and, following this technique, the use of self-tapping implants is highly recommended. Implant stability optimization in the soft bone can be achieved by lateral bone-condensing technique, regardless of implant macro-design.",
publisher = "Wiley, Hoboken",
journal = "Clinical Implant Dentistry & Related Research",
title = "Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study",
volume = "15",
number = "3",
pages = "341-349",
doi = "10.1111/j.1708-8208.2011.00415.x"
}

Marković, A., Luis Calvo-Guirado, J., Lazić, Z., Gomez-Moreno, G., Ćalasan, D., Guardia, J., Čolić, S., Aguilar-Salvatierra, A., Gačić, B., Delgado-Ruiz, R., Janjić, B.,& Mišić, T.. (2013). Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study. in Clinical Implant Dentistry & Related Research
Wiley, Hoboken., 15(3), 341-349.
https://doi.org/10.1111/j.1708-8208.2011.00415.x

Marković A, Luis Calvo-Guirado J, Lazić Z, Gomez-Moreno G, Ćalasan D, Guardia J, Čolić S, Aguilar-Salvatierra A, Gačić B, Delgado-Ruiz R, Janjić B, Mišić T. Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study. in Clinical Implant Dentistry & Related Research. 2013;15(3):341-349.
doi:10.1111/j.1708-8208.2011.00415.x .

Marković, Aleksa, Luis Calvo-Guirado, Jose, Lazić, Zoran, Gomez-Moreno, Gerardo, Ćalasan, Dejan, Guardia, Javier, Čolić, Snježana, Aguilar-Salvatierra, Antonio, Gačić, Bojan, Delgado-Ruiz, Rafael, Janjić, Bojan, Mišić, Tijana, "Evaluation of Primary Stability of Self-Tapping and Non-Self-Tapping Dental Implants. A 12-Week Clinical Study" in Clinical Implant Dentistry & Related Research, 15, no. 3 (2013):341-349,
https://doi.org/10.1111/j.1708-8208.2011.00415.x . .

TY  - JOUR
AU  - Šćepanović, Miodrag
AU  - Luis Calvo-Guirado, Jose
AU  - Marković, Aleksa
AU  - Delgado-Ruiz, Rafael
AU  - Todorović, Aleksandar
AU  - Miličić, Biljana
AU  - Mišić, Tijana
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1687
AB  - Aim: The aim of this 1-year prospective cohort study was to evaluate the outcomes and complications of immediately loaded mini dental implants used for stabilizing mandibular overdentures in edentulous patients wearing conventional complete dentures. Materials and methods: Thirty patients received mandibular conventional complete dentures that were subsequently retained by 4 immediately loaded mini dental implants placed in the interforaminal region. Overdenture success, implant success and biological and prosthetic complications were evaluated after the first year of service. Quality of life using the Oral Heath Impact Profile (OHIP)-EDENT test, satisfaction with dental prosthesis and chewing efficiency using questionnaires and a Visual Analogue Scale (VAS) were evaluated twice: after they had received mandibular complete dentures, and again after they had received mandibular overdentures. Results: After 1 year, no overdenture failed and 2 implants did not osseointegrate, resulting in a 98.3% success rate for loaded implants and 95.9% for total implants used (3 out of 123 were not loaded due to fracture). A flap surgical approach was performed in 7 patients, 3 implants fractured during insertion, 3 overdentures fractured, occlusion balancing was necessary for 11 dentures and relining for 8. Implant rehabilitation provided significant improvement in quality of life, stability, comfort, chewing and speaking ability while no significant differences were found in quality of maintenance of hygiene and for aesthetics. Conclusions: Mini dental implant retained overdentures can be a successful therapeutic procedure for treating mandibular edentulism that improves quality of life, patient satisfaction and chewing ability in patients wearing maxillary dentures. Longer follow-ups are needed to validate this therapy in the medium and long-term.
PB  - Quintessence Publishing Co., Ltd
T2  - European Journal of Oral Implantology
T1  - A 1-year prospective cohort study on mandibular overdentures retained by mini dental implants
VL  - 5
IS  - 4
SP  - 367
EP  - 379
UR  - https://hdl.handle.net/21.15107/rcub_smile_1687
ER  - 

@article{
author = "Šćepanović, Miodrag and Luis Calvo-Guirado, Jose and Marković, Aleksa and Delgado-Ruiz, Rafael and Todorović, Aleksandar and Miličić, Biljana and Mišić, Tijana",
year = "2012",
abstract = "Aim: The aim of this 1-year prospective cohort study was to evaluate the outcomes and complications of immediately loaded mini dental implants used for stabilizing mandibular overdentures in edentulous patients wearing conventional complete dentures. Materials and methods: Thirty patients received mandibular conventional complete dentures that were subsequently retained by 4 immediately loaded mini dental implants placed in the interforaminal region. Overdenture success, implant success and biological and prosthetic complications were evaluated after the first year of service. Quality of life using the Oral Heath Impact Profile (OHIP)-EDENT test, satisfaction with dental prosthesis and chewing efficiency using questionnaires and a Visual Analogue Scale (VAS) were evaluated twice: after they had received mandibular complete dentures, and again after they had received mandibular overdentures. Results: After 1 year, no overdenture failed and 2 implants did not osseointegrate, resulting in a 98.3% success rate for loaded implants and 95.9% for total implants used (3 out of 123 were not loaded due to fracture). A flap surgical approach was performed in 7 patients, 3 implants fractured during insertion, 3 overdentures fractured, occlusion balancing was necessary for 11 dentures and relining for 8. Implant rehabilitation provided significant improvement in quality of life, stability, comfort, chewing and speaking ability while no significant differences were found in quality of maintenance of hygiene and for aesthetics. Conclusions: Mini dental implant retained overdentures can be a successful therapeutic procedure for treating mandibular edentulism that improves quality of life, patient satisfaction and chewing ability in patients wearing maxillary dentures. Longer follow-ups are needed to validate this therapy in the medium and long-term.",
publisher = "Quintessence Publishing Co., Ltd",
journal = "European Journal of Oral Implantology",
title = "A 1-year prospective cohort study on mandibular overdentures retained by mini dental implants",
volume = "5",
number = "4",
pages = "367-379",
url = "https://hdl.handle.net/21.15107/rcub_smile_1687"
}

Šćepanović, M., Luis Calvo-Guirado, J., Marković, A., Delgado-Ruiz, R., Todorović, A., Miličić, B.,& Mišić, T.. (2012). A 1-year prospective cohort study on mandibular overdentures retained by mini dental implants. in European Journal of Oral Implantology
Quintessence Publishing Co., Ltd., 5(4), 367-379.
https://hdl.handle.net/21.15107/rcub_smile_1687

Šćepanović M, Luis Calvo-Guirado J, Marković A, Delgado-Ruiz R, Todorović A, Miličić B, Mišić T. A 1-year prospective cohort study on mandibular overdentures retained by mini dental implants. in European Journal of Oral Implantology. 2012;5(4):367-379.
https://hdl.handle.net/21.15107/rcub_smile_1687 .

Šćepanović, Miodrag, Luis Calvo-Guirado, Jose, Marković, Aleksa, Delgado-Ruiz, Rafael, Todorović, Aleksandar, Miličić, Biljana, Mišić, Tijana, "A 1-year prospective cohort study on mandibular overdentures retained by mini dental implants" in European Journal of Oral Implantology, 5, no. 4 (2012):367-379,
https://hdl.handle.net/21.15107/rcub_smile_1687 .

TY  - THES
AU  - Mišić, Tijana
PY  - 2012
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=1626
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:9134/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=45155599
UR  - http://nardus.mpn.gov.rs/123456789/2701
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/951
AB  - The posterior maxilla consists of low density bone in which primary stability of the implant which is necessary for unobstructed healing is difficult to obtain. In order to achieve good implant primary stability, the placement of self tapping implants after lateral bone condensing is recommended. During surgical implant procedures, friction heat is generated in the implant site. Bone temperature of 47°C lasting for 1 min destroys the regenerative potential of the bone tissue, causes resorption of the bone and diminishes the mechanic features which can result in early failure of implant therapy. The prevention of excessive heating of the bone tissue during implant site preparation and implant placement is a key requirement for successful osseointegration. The aims of the dissertation are: 1. To compare the bone thermal changes in lateral bone condensing and bone drilling technique. 2. To examine the effect of the temperature of the saline solution for cooling the bone during implant site preparation and implant placement. 3. To compare the bone thermal changes during implant placement after lateral bone condensing technique and bone drilling technique. 4. To compare the bone thermal changes during implant placement using Insertion torque value of 30, 35, 40 Ncm. 5. To compare the bone thermal changes during placement of self tapping and non self tapping implants. 6. To examine the influence of age and gender of the patients on the bone thermal change during implant placement. 7. To examine the influence of bone density at the recipient site as well as region of the implantation on the bone thermal changes during implant placement. In order to study and examine the influence of surgical technique on the temperature of the low density bone in implant site preparation and implant placement, experimental and clinical research has been conducted. In the experimental study as a bone model, a pig rib was used with uniform thickness of the cortical layer of 2mm. The temperature was measured using 3 thermocouples placed in distance of 0,5mm from the implant site, with vertical depth of 1mm, 5mm, 10mm. Two sets of experiments have been conducted. In the first set of experiments, the effect o surgical technique on the bone thermal change was examined during implant site preparation in which lateral bone condensing technique (experimental group) and standard bone drilling technique ( control group ) were compared. Implant site preparation was conducted without irrigation, with irrigation using room temperature saline solution and saline solution of 5 °C. The second set of experiments were conducted with the aim of examining the effect of surgical technique (lateral bone condensing technique and bone drilling) on bone temperature during implant site preparation and implant placement. In the randomized, controlled clinical study, 14 patients were included of both gender (8 women and 6 men) and average age 51.3 ( from 30 to 63), in whose posterior maxilla a total of 30 implants were placed: 15 after lateral bone condensing (study group) and 15 after bone drilling ( control group )...
AB  - Bočni segment gornje vilice čini kost male gustine u kojoj je teško postići primarnu stabilnost implantata neophodnu za neomeano zarastanje...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Experimental and clinical study of effect of surgical technique on temperature of low density bone during implant site preparation and implant placement
T1  - Eksperimentalno i kliničko ispitivanje uticaja hirurške tehnike na temperaturu kosti male gustine tokom preparacije ležišta i ugradnje implantata
UR  - https://hdl.handle.net/21.15107/rcub_nardus_2701
ER  - 

@phdthesis{
author = "Mišić, Tijana",
year = "2012",
abstract = "The posterior maxilla consists of low density bone in which primary stability of the implant which is necessary for unobstructed healing is difficult to obtain. In order to achieve good implant primary stability, the placement of self tapping implants after lateral bone condensing is recommended. During surgical implant procedures, friction heat is generated in the implant site. Bone temperature of 47°C lasting for 1 min destroys the regenerative potential of the bone tissue, causes resorption of the bone and diminishes the mechanic features which can result in early failure of implant therapy. The prevention of excessive heating of the bone tissue during implant site preparation and implant placement is a key requirement for successful osseointegration. The aims of the dissertation are: 1. To compare the bone thermal changes in lateral bone condensing and bone drilling technique. 2. To examine the effect of the temperature of the saline solution for cooling the bone during implant site preparation and implant placement. 3. To compare the bone thermal changes during implant placement after lateral bone condensing technique and bone drilling technique. 4. To compare the bone thermal changes during implant placement using Insertion torque value of 30, 35, 40 Ncm. 5. To compare the bone thermal changes during placement of self tapping and non self tapping implants. 6. To examine the influence of age and gender of the patients on the bone thermal change during implant placement. 7. To examine the influence of bone density at the recipient site as well as region of the implantation on the bone thermal changes during implant placement. In order to study and examine the influence of surgical technique on the temperature of the low density bone in implant site preparation and implant placement, experimental and clinical research has been conducted. In the experimental study as a bone model, a pig rib was used with uniform thickness of the cortical layer of 2mm. The temperature was measured using 3 thermocouples placed in distance of 0,5mm from the implant site, with vertical depth of 1mm, 5mm, 10mm. Two sets of experiments have been conducted. In the first set of experiments, the effect o surgical technique on the bone thermal change was examined during implant site preparation in which lateral bone condensing technique (experimental group) and standard bone drilling technique ( control group ) were compared. Implant site preparation was conducted without irrigation, with irrigation using room temperature saline solution and saline solution of 5 °C. The second set of experiments were conducted with the aim of examining the effect of surgical technique (lateral bone condensing technique and bone drilling) on bone temperature during implant site preparation and implant placement. In the randomized, controlled clinical study, 14 patients were included of both gender (8 women and 6 men) and average age 51.3 ( from 30 to 63), in whose posterior maxilla a total of 30 implants were placed: 15 after lateral bone condensing (study group) and 15 after bone drilling ( control group )..., Bočni segment gornje vilice čini kost male gustine u kojoj je teško postići primarnu stabilnost implantata neophodnu za neomeano zarastanje...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Experimental and clinical study of effect of surgical technique on temperature of low density bone during implant site preparation and implant placement, Eksperimentalno i kliničko ispitivanje uticaja hirurške tehnike na temperaturu kosti male gustine tokom preparacije ležišta i ugradnje implantata",
url = "https://hdl.handle.net/21.15107/rcub_nardus_2701"
}

Mišić, T.. (2012). Experimental and clinical study of effect of surgical technique on temperature of low density bone during implant site preparation and implant placement. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_2701

Mišić T. Experimental and clinical study of effect of surgical technique on temperature of low density bone during implant site preparation and implant placement. 2012;.
https://hdl.handle.net/21.15107/rcub_nardus_2701 .

Mišić, Tijana, "Experimental and clinical study of effect of surgical technique on temperature of low density bone during implant site preparation and implant placement" (2012),
https://hdl.handle.net/21.15107/rcub_nardus_2701 .

TY  - JOUR
AU  - Mišić, Tijana
AU  - Marković, Aleksa
AU  - Todorović, Aleksandar
AU  - Čolić, Snježana
AU  - Šćepanović, Miodrag
AU  - Miličić, Biljana
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1621
AB  - Objective. The aim of this study was to compare changes in temperature of the surrounding bone at various osteotomy depths during implant site preparation by bone condensing and by bone drilling as well as the dynamics of their change. Study design. In the present "in vitro" study, pig ribs with uniform thickness of cortical bone of 2 mm were used. Lateral bone-condensing (experimental group) and bone-drilling techniques (control group) were performed. Temperature changes were recorded at a distance of 0.5 mm from the final test osteotomy by 3 thermocouples at the depths of 1, 5, and 10 mm in tripod configuration. Data were collected from 48 measurements, 24 for each group. Results. Significantly higher mean temperature increase at the depth of 5 mm was observed during bone drilling compared with bone condensing, whereas for the depths of 1 and 10 mm differences were not significant between the 2 surgical techniques. During bone condensing, the mean temperature rise was continuously decreasing with increasing depth of osteotomies, whereas during bone drilling the mean temperature rise was first increased and reached a peak at the depth of 5 mm and then began to decrease with increasing depth of the osteotomies. Conclusions. The bone-condensing technique applied in the jaw bone class D4 offers an advantage over bone drilling because it generates a significantly smaller amount of heat. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 28-33)
PB  - Mosby-Elsevier, New York
T2  - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
T1  - An in vitro study of temperature changes in type 4 bone during implant placement: bone condensing versus bone drilling
VL  - 112
IS  - 1
SP  - 28
EP  - 33
DO  - 10.1016/j.tripleo.2010.08.010
ER  - 

@article{
author = "Mišić, Tijana and Marković, Aleksa and Todorović, Aleksandar and Čolić, Snježana and Šćepanović, Miodrag and Miličić, Biljana",
year = "2011",
abstract = "Objective. The aim of this study was to compare changes in temperature of the surrounding bone at various osteotomy depths during implant site preparation by bone condensing and by bone drilling as well as the dynamics of their change. Study design. In the present "in vitro" study, pig ribs with uniform thickness of cortical bone of 2 mm were used. Lateral bone-condensing (experimental group) and bone-drilling techniques (control group) were performed. Temperature changes were recorded at a distance of 0.5 mm from the final test osteotomy by 3 thermocouples at the depths of 1, 5, and 10 mm in tripod configuration. Data were collected from 48 measurements, 24 for each group. Results. Significantly higher mean temperature increase at the depth of 5 mm was observed during bone drilling compared with bone condensing, whereas for the depths of 1 and 10 mm differences were not significant between the 2 surgical techniques. During bone condensing, the mean temperature rise was continuously decreasing with increasing depth of osteotomies, whereas during bone drilling the mean temperature rise was first increased and reached a peak at the depth of 5 mm and then began to decrease with increasing depth of the osteotomies. Conclusions. The bone-condensing technique applied in the jaw bone class D4 offers an advantage over bone drilling because it generates a significantly smaller amount of heat. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 28-33)",
publisher = "Mosby-Elsevier, New York",
journal = "Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology",
title = "An in vitro study of temperature changes in type 4 bone during implant placement: bone condensing versus bone drilling",
volume = "112",
number = "1",
pages = "28-33",
doi = "10.1016/j.tripleo.2010.08.010"
}

Mišić, T., Marković, A., Todorović, A., Čolić, S., Šćepanović, M.,& Miličić, B.. (2011). An in vitro study of temperature changes in type 4 bone during implant placement: bone condensing versus bone drilling. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
Mosby-Elsevier, New York., 112(1), 28-33.
https://doi.org/10.1016/j.tripleo.2010.08.010

Mišić T, Marković A, Todorović A, Čolić S, Šćepanović M, Miličić B. An in vitro study of temperature changes in type 4 bone during implant placement: bone condensing versus bone drilling. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology. 2011;112(1):28-33.
doi:10.1016/j.tripleo.2010.08.010 .

Mišić, Tijana, Marković, Aleksa, Todorović, Aleksandar, Čolić, Snježana, Šćepanović, Miodrag, Miličić, Biljana, "An in vitro study of temperature changes in type 4 bone during implant placement: bone condensing versus bone drilling" in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology, 112, no. 1 (2011):28-33,
https://doi.org/10.1016/j.tripleo.2010.08.010 . .

TY  - JOUR
AU  - Marković, Aleksa
AU  - Ćalasan, Dejan
AU  - Čolić, Snježana
AU  - Stojčev-Stajčić, Ljiljana
AU  - Janjić, Bojan
AU  - Mišić, Tijana
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1612
AB  - Objective. The aim of this clinical trial was to compare primary and secondary stability of implants placed by bone condensing versus the standard drilling technique in the posterior edentulous maxilla. Study design. Forty-eight SLA Straumann implants 4.1 x 10 mm (Institut Straumann AG, Waldenburg, Switzerland) were placed into edentulous maxillary posterior region in the same positions bilaterally, using the bone condensation technique for one and the standard technique for the other side. Implant stability measurements were performed immediately after implant placement, as well as every week for the next 6 weeks by use of resonance frequency analysis (RFA). Data were analyzed using Mann-Whitney U and Wilcoxon tests. Results. After bone condensing, significantly higher implant stability was recorded immediately after surgery as well as during the whole observation period of 6 weeks compared with bone-drilling technique (Mann-Whitney U test, P  lt  .000). Conclusions. The bone-condensing technique can be recommended as an alternate surgical approach for implant site preparation in reduced bone density to achieve greater implant stability in the posterior maxilla. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 557-563)
PB  - Mosby-Elsevier, New York
T2  - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
T1  - Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study
VL  - 112
IS  - 5
SP  - 557
EP  - 563
DO  - 10.1016/j.tripleo.2010.11.010
ER  - 

@article{
author = "Marković, Aleksa and Ćalasan, Dejan and Čolić, Snježana and Stojčev-Stajčić, Ljiljana and Janjić, Bojan and Mišić, Tijana",
year = "2011",
abstract = "Objective. The aim of this clinical trial was to compare primary and secondary stability of implants placed by bone condensing versus the standard drilling technique in the posterior edentulous maxilla. Study design. Forty-eight SLA Straumann implants 4.1 x 10 mm (Institut Straumann AG, Waldenburg, Switzerland) were placed into edentulous maxillary posterior region in the same positions bilaterally, using the bone condensation technique for one and the standard technique for the other side. Implant stability measurements were performed immediately after implant placement, as well as every week for the next 6 weeks by use of resonance frequency analysis (RFA). Data were analyzed using Mann-Whitney U and Wilcoxon tests. Results. After bone condensing, significantly higher implant stability was recorded immediately after surgery as well as during the whole observation period of 6 weeks compared with bone-drilling technique (Mann-Whitney U test, P  lt  .000). Conclusions. The bone-condensing technique can be recommended as an alternate surgical approach for implant site preparation in reduced bone density to achieve greater implant stability in the posterior maxilla. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 557-563)",
publisher = "Mosby-Elsevier, New York",
journal = "Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology",
title = "Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study",
volume = "112",
number = "5",
pages = "557-563",
doi = "10.1016/j.tripleo.2010.11.010"
}

Marković, A., Ćalasan, D., Čolić, S., Stojčev-Stajčić, L., Janjić, B.,& Mišić, T.. (2011). Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology
Mosby-Elsevier, New York., 112(5), 557-563.
https://doi.org/10.1016/j.tripleo.2010.11.010

Marković A, Ćalasan D, Čolić S, Stojčev-Stajčić L, Janjić B, Mišić T. Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study. in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology. 2011;112(5):557-563.
doi:10.1016/j.tripleo.2010.11.010 .

Marković, Aleksa, Ćalasan, Dejan, Čolić, Snježana, Stojčev-Stajčić, Ljiljana, Janjić, Bojan, Mišić, Tijana, "Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study" in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontology, 112, no. 5 (2011):557-563,
https://doi.org/10.1016/j.tripleo.2010.11.010 . .