TY  - JOUR
AU  - Popovac, Aleksandra
AU  - Mladenović, Irena
AU  - Krunić, Jelena
AU  - Trifković, Branka
AU  - Todorović, Ana
AU  - Milašin, Jelena
AU  - Despotović, Nebojša
AU  - Stančić, Ivica
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2517
AB  - Compromised dentition has been suggested to pose a significant risk factor for dementia. It was mainly investigated through insufficient tooth number, disregarding contact between opposing teeth (dental occlusion). The epsilon 4 allele of apolipoprotein (APOE4) is the primary genetic marker for the late onset of Alzheimer's disease (AD). However, APOE4 and dental occlusion have not yet been investigated as possible associated risk factors for AD. The study was aimed to examine the impact of dental status and different APOE gene variants on AD occurrence. Secondly, sociodemographic variables were investigated as factors potentially associated with AD. The case-control study included two groups: 116 patients with AD (according to the NINDS-ADRDA criteria) and 63 controls (Mini-Mental State Examination scores >= 24). The analysis of APOE gene polymorphism was conducted through PCR reaction. Dental examination included recording of number of teeth, presence of fixed or removable dentures, and number of functional tooth units (FTU). Regression analysis was used to investigate the joint effect of the clinical and genetic variables on AD. Results showed that patients with AD were more often carriers of epsilon 3/epsilon 4 genotype and epsilon 4 allele, had lower number of teeth and FTU, and were less likely to be married, live in home, and had less chronic diseases, compared to the controls. Regression analysis showed that presence of APOE4 allele and the number of total FTU remained associated with AD, even when adjusted for age, sex, and level of education. In conclusion, deficient dental occlusion and presence of APOE4 may independently increase risk for AD.
PB  - Ios Press, Amsterdam
T2  - Journal of Alzheimers Disease
T1  - Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease
VL  - 74
IS  - 3
SP  - 797
EP  - 802
DO  - 10.3233/JAD-191283
ER  - 

@article{
author = "Popovac, Aleksandra and Mladenović, Irena and Krunić, Jelena and Trifković, Branka and Todorović, Ana and Milašin, Jelena and Despotović, Nebojša and Stančić, Ivica",
year = "2020",
abstract = "Compromised dentition has been suggested to pose a significant risk factor for dementia. It was mainly investigated through insufficient tooth number, disregarding contact between opposing teeth (dental occlusion). The epsilon 4 allele of apolipoprotein (APOE4) is the primary genetic marker for the late onset of Alzheimer's disease (AD). However, APOE4 and dental occlusion have not yet been investigated as possible associated risk factors for AD. The study was aimed to examine the impact of dental status and different APOE gene variants on AD occurrence. Secondly, sociodemographic variables were investigated as factors potentially associated with AD. The case-control study included two groups: 116 patients with AD (according to the NINDS-ADRDA criteria) and 63 controls (Mini-Mental State Examination scores >= 24). The analysis of APOE gene polymorphism was conducted through PCR reaction. Dental examination included recording of number of teeth, presence of fixed or removable dentures, and number of functional tooth units (FTU). Regression analysis was used to investigate the joint effect of the clinical and genetic variables on AD. Results showed that patients with AD were more often carriers of epsilon 3/epsilon 4 genotype and epsilon 4 allele, had lower number of teeth and FTU, and were less likely to be married, live in home, and had less chronic diseases, compared to the controls. Regression analysis showed that presence of APOE4 allele and the number of total FTU remained associated with AD, even when adjusted for age, sex, and level of education. In conclusion, deficient dental occlusion and presence of APOE4 may independently increase risk for AD.",
publisher = "Ios Press, Amsterdam",
journal = "Journal of Alzheimers Disease",
title = "Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease",
volume = "74",
number = "3",
pages = "797-802",
doi = "10.3233/JAD-191283"
}

Popovac, A., Mladenović, I., Krunić, J., Trifković, B., Todorović, A., Milašin, J., Despotović, N.,& Stančić, I.. (2020). Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease. in Journal of Alzheimers Disease
Ios Press, Amsterdam., 74(3), 797-802.
https://doi.org/10.3233/JAD-191283

Popovac A, Mladenović I, Krunić J, Trifković B, Todorović A, Milašin J, Despotović N, Stančić I. Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease. in Journal of Alzheimers Disease. 2020;74(3):797-802.
doi:10.3233/JAD-191283 .

Popovac, Aleksandra, Mladenović, Irena, Krunić, Jelena, Trifković, Branka, Todorović, Ana, Milašin, Jelena, Despotović, Nebojša, Stančić, Ivica, "Apolipoprotein epsilon 4 Allele and Dental Occlusion Deficiency as Risk Factors for Alzheimer's Disease" in Journal of Alzheimers Disease, 74, no. 3 (2020):797-802,
https://doi.org/10.3233/JAD-191283 . .

TY  - JOUR
AU  - Radović, Igor
AU  - Stojanović, Nikola
AU  - Krunić, Jelena
AU  - Davidović, Lado
AU  - Lečić, Jelena
AU  - Jokanović, Vukoman
AU  - Živković, Slavoljub
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2430
AB  - Introduction Materials used for root canal obturation and root perforation are expected to have, in addition to preventing apical, lateral and coronary leakage, antimicrobial effects on microorganisms that are not accessible to chemomechanical instrumentation and intra-canal medications. The aim of this study was to evaluate the antimicrobial effect of a novel calcium aluminate-based endodontic nanostructured biomaterial (ALBO-MCCA) using agar diffusion test. Material and methods the two materials were tested in the study. The nanostructured calcium aluminate was synthesized by the hydrothermal sol-gel method from individual components of calcium aluminate (CaOxAl2 O3 ), calcite (CaCO3 ) and barium sulfate (BaSO4 ) as radiocontrast agent in the ratio of 2:2:1 according to V. Jokanovic's recipe. The other used material was calcium silicate MTA Angelus (Londrina, Brazil). The antimicrobial effect was assessed using agar diffusion test. Standard strains of Enterococcus faecalis, Escherichia coli, Staphylococcus aureus, cultured on blood Mueller-Hinton agar and Candida albicans cultivated on Sabouraud Dextrose Agar, were used as test microorganisms. Results the best antimicrobial effect after 24 h both materials showed against S. aureus. The mean values of the growth inhibition zone for ALBO MCCA were 5.7 ± 0.25 mm and MTA 6.2 ± 0.4 mm. The ALBO MCCA material showed slightly stronger antibacterial effect against E. coli compared to MTA (p  lt  0.05), whereas none of the materials showed antibacterial effect against E. faecalis. Conclusion the ALBO MCCA material showed certain antibacterial effect on Escherichia coli, Staphylococcus aureus and Candida albicans that was comparable to antibacterial effect of MTA.
AB  - Uvod Od materijala koji se koriste za opturaciju kanala korena i perforacija na korenu se očekuje da pored sprečavanja apikalnog, lateralnog i koronarnog curenja, poseduju i antimikrobno delovanje na mikroorganizme, koji nisu dostupni hemomehaničkoj obradi i intrakanalnim medikamentima. Cilj ovog istraživanja je bio da se testom difuzije u agaru proceni antimikrobni efekat novog endodontskog nanostrukturnog biomaterijala na bazi kalcijum-aluminata (ALBO-MCCA). Materijal i metode U istraživanju su korišćena dva materijala. Nanostrukturni kalcijum-aluminat je sintetisan hidrotermalnom sol-gel metodom od pojedinačnih komponenata kalcijum-aluminata (CaO·Al2 O3 ), kalcita (CaCO3 ) i barijum-sulfata (BaSO4 ) kao rendgen-kontrastnog sredstva u odnosu 2 : 2 : 1 prema recepturi V. Jokanovića. Drugi korišćeni materijal je kalcijum-silikatni MTA Angelus (Londrina, Brazil). Antimikrobni efekat je ispitivan testom difuzije u agaru. Kao test mikroorganizmi korišćeni su standardni sojevi Enterococcus faecalis, Escherichia coli, Staphylococcus aureus, koji su kultivisani na krvnom agaru MuellerHinton, dok je C. albicans kultivisana na agaru Sabouraud Dextrose. Rezultati Najbolji antimikrobni efekat nakon 24 h oba materijala su pokazala prema bakteriji S. aureus. Izmerene prosečne vrednosti zone inhibicije rasta iznosile su kod ALBO-MCCA (5,7 ± 0,25 mm), odnosno kod MTA (6,2 ± 0,4 mm). Materijal ALBO-MCCA je pokazao nešto veći antibakterijski efekat prema bakteriji E. coli u odnosu na MTA (p  lt  0,05), dok prema bakteriji E. faecalis nijedan materijal nije ispoljio antibakterijski efekat. Zaključak Materijal ALBO-MCCA je ispoljio određeni antibakterijski efekat na bakterije Escherichia coli, Staphylococcus aureus i Candida albicans komparabilan sa antibakterijskim efektom MTA.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Antibacterial activity of newly synthesized endodontic nanomaterial based on calcium aluminate
T1  - Antimikrobna aktivnost novosintetisanog endodontskog nanomaterijala na bazi kalcijum-aluminata
VL  - 66
IS  - 3
SP  - 113
EP  - 119
DO  - 10.2478/sdj-2019-0012
ER  - 

@article{
author = "Radović, Igor and Stojanović, Nikola and Krunić, Jelena and Davidović, Lado and Lečić, Jelena and Jokanović, Vukoman and Živković, Slavoljub",
year = "2019",
abstract = "Introduction Materials used for root canal obturation and root perforation are expected to have, in addition to preventing apical, lateral and coronary leakage, antimicrobial effects on microorganisms that are not accessible to chemomechanical instrumentation and intra-canal medications. The aim of this study was to evaluate the antimicrobial effect of a novel calcium aluminate-based endodontic nanostructured biomaterial (ALBO-MCCA) using agar diffusion test. Material and methods the two materials were tested in the study. The nanostructured calcium aluminate was synthesized by the hydrothermal sol-gel method from individual components of calcium aluminate (CaOxAl2 O3 ), calcite (CaCO3 ) and barium sulfate (BaSO4 ) as radiocontrast agent in the ratio of 2:2:1 according to V. Jokanovic's recipe. The other used material was calcium silicate MTA Angelus (Londrina, Brazil). The antimicrobial effect was assessed using agar diffusion test. Standard strains of Enterococcus faecalis, Escherichia coli, Staphylococcus aureus, cultured on blood Mueller-Hinton agar and Candida albicans cultivated on Sabouraud Dextrose Agar, were used as test microorganisms. Results the best antimicrobial effect after 24 h both materials showed against S. aureus. The mean values of the growth inhibition zone for ALBO MCCA were 5.7 ± 0.25 mm and MTA 6.2 ± 0.4 mm. The ALBO MCCA material showed slightly stronger antibacterial effect against E. coli compared to MTA (p  lt  0.05), whereas none of the materials showed antibacterial effect against E. faecalis. Conclusion the ALBO MCCA material showed certain antibacterial effect on Escherichia coli, Staphylococcus aureus and Candida albicans that was comparable to antibacterial effect of MTA., Uvod Od materijala koji se koriste za opturaciju kanala korena i perforacija na korenu se očekuje da pored sprečavanja apikalnog, lateralnog i koronarnog curenja, poseduju i antimikrobno delovanje na mikroorganizme, koji nisu dostupni hemomehaničkoj obradi i intrakanalnim medikamentima. Cilj ovog istraživanja je bio da se testom difuzije u agaru proceni antimikrobni efekat novog endodontskog nanostrukturnog biomaterijala na bazi kalcijum-aluminata (ALBO-MCCA). Materijal i metode U istraživanju su korišćena dva materijala. Nanostrukturni kalcijum-aluminat je sintetisan hidrotermalnom sol-gel metodom od pojedinačnih komponenata kalcijum-aluminata (CaO·Al2 O3 ), kalcita (CaCO3 ) i barijum-sulfata (BaSO4 ) kao rendgen-kontrastnog sredstva u odnosu 2 : 2 : 1 prema recepturi V. Jokanovića. Drugi korišćeni materijal je kalcijum-silikatni MTA Angelus (Londrina, Brazil). Antimikrobni efekat je ispitivan testom difuzije u agaru. Kao test mikroorganizmi korišćeni su standardni sojevi Enterococcus faecalis, Escherichia coli, Staphylococcus aureus, koji su kultivisani na krvnom agaru MuellerHinton, dok je C. albicans kultivisana na agaru Sabouraud Dextrose. Rezultati Najbolji antimikrobni efekat nakon 24 h oba materijala su pokazala prema bakteriji S. aureus. Izmerene prosečne vrednosti zone inhibicije rasta iznosile su kod ALBO-MCCA (5,7 ± 0,25 mm), odnosno kod MTA (6,2 ± 0,4 mm). Materijal ALBO-MCCA je pokazao nešto veći antibakterijski efekat prema bakteriji E. coli u odnosu na MTA (p  lt  0,05), dok prema bakteriji E. faecalis nijedan materijal nije ispoljio antibakterijski efekat. Zaključak Materijal ALBO-MCCA je ispoljio određeni antibakterijski efekat na bakterije Escherichia coli, Staphylococcus aureus i Candida albicans komparabilan sa antibakterijskim efektom MTA.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Antibacterial activity of newly synthesized endodontic nanomaterial based on calcium aluminate, Antimikrobna aktivnost novosintetisanog endodontskog nanomaterijala na bazi kalcijum-aluminata",
volume = "66",
number = "3",
pages = "113-119",
doi = "10.2478/sdj-2019-0012"
}

Radović, I., Stojanović, N., Krunić, J., Davidović, L., Lečić, J., Jokanović, V.,& Živković, S.. (2019). Antibacterial activity of newly synthesized endodontic nanomaterial based on calcium aluminate. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 66(3), 113-119.
https://doi.org/10.2478/sdj-2019-0012

Radović I, Stojanović N, Krunić J, Davidović L, Lečić J, Jokanović V, Živković S. Antibacterial activity of newly synthesized endodontic nanomaterial based on calcium aluminate. in Stomatološki glasnik Srbije. 2019;66(3):113-119.
doi:10.2478/sdj-2019-0012 .

Radović, Igor, Stojanović, Nikola, Krunić, Jelena, Davidović, Lado, Lečić, Jelena, Jokanović, Vukoman, Živković, Slavoljub, "Antibacterial activity of newly synthesized endodontic nanomaterial based on calcium aluminate" in Stomatološki glasnik Srbije, 66, no. 3 (2019):113-119,
https://doi.org/10.2478/sdj-2019-0012 . .

TY  - JOUR
AU  - Zuza, Aleksandra
AU  - Racić, Maja
AU  - Ivković, Nedeljka
AU  - Krunić, Jelena
AU  - Stojanović, Nikola
AU  - Božović, Đorđe
AU  - Banković-Lazarević, Dušica
AU  - Vujašković, Mirjana
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2394
AB  - Introduction As non-carious cervical lesions (NCCLs) may compromise aesthetics and function, knowledge of their aetiological covariables enhances management of clinical complaints and success of restorative treatments. Aims The primary aim of this study was to assess the presence of NCCLs among the general population of the Republic of Srpska, Bosnia and Herzegovina and the potential association with patient-related risk factors. Methods A prevalence study of NCCLs included 738 respondents from eight towns/municipalities. Two dental practitioners examined all respondents. NCCLs were diagnosed according to the Smith and Knight tooth wear index, measured using a Williams periodontal probe. Data regarding risk factors were obtained through a structured questionnaire. Multivariate logistic regression was used to analyse the association of risk factors and the occurrence of NCCLs. Results Non-carious cervical lesions were diagnosed in 384 (52%) respondents. Multivariate regression analysis showed that several variables were independently associated with the risk of developing NCCLs, including frequent consumption of acid food (P = 0.001), frequent consumption of acid drinks (P = 0.001), retaining drink in the mouth (P = 0.001), alcohol consumption (P = 0.030), bruxism (P = 0.018) and gastro-oesophageal reflux (P = 0.023). First mandibular premolars were the most affected teeth (left: 46.0%; right: 44.0%), followed by the second right maxillary premolars (37.3%), second left maxillary premolars (33.6%) and finally by the first right maxillary premolars (34.0%). Conclusion The results of the current study suggest that NCCLs occur frequently and have a multifactorial aetiology. The lowest prevalence was recorded among individuals younger than 20 years of age. As the majority of risk factors are modifiable, regular dental care could lead to the early detection of NCCLs.
PB  - Wiley, Hoboken
T2  - International Dental Journal
T1  - Prevalence of non-carious cervical lesions among the general population of the Republic of Srpska, Bosnia and Herzegovina
VL  - 69
IS  - 4
SP  - 281
EP  - 288
DO  - 10.1111/idj.12462
ER  - 

@article{
author = "Zuza, Aleksandra and Racić, Maja and Ivković, Nedeljka and Krunić, Jelena and Stojanović, Nikola and Božović, Đorđe and Banković-Lazarević, Dušica and Vujašković, Mirjana",
year = "2019",
abstract = "Introduction As non-carious cervical lesions (NCCLs) may compromise aesthetics and function, knowledge of their aetiological covariables enhances management of clinical complaints and success of restorative treatments. Aims The primary aim of this study was to assess the presence of NCCLs among the general population of the Republic of Srpska, Bosnia and Herzegovina and the potential association with patient-related risk factors. Methods A prevalence study of NCCLs included 738 respondents from eight towns/municipalities. Two dental practitioners examined all respondents. NCCLs were diagnosed according to the Smith and Knight tooth wear index, measured using a Williams periodontal probe. Data regarding risk factors were obtained through a structured questionnaire. Multivariate logistic regression was used to analyse the association of risk factors and the occurrence of NCCLs. Results Non-carious cervical lesions were diagnosed in 384 (52%) respondents. Multivariate regression analysis showed that several variables were independently associated with the risk of developing NCCLs, including frequent consumption of acid food (P = 0.001), frequent consumption of acid drinks (P = 0.001), retaining drink in the mouth (P = 0.001), alcohol consumption (P = 0.030), bruxism (P = 0.018) and gastro-oesophageal reflux (P = 0.023). First mandibular premolars were the most affected teeth (left: 46.0%; right: 44.0%), followed by the second right maxillary premolars (37.3%), second left maxillary premolars (33.6%) and finally by the first right maxillary premolars (34.0%). Conclusion The results of the current study suggest that NCCLs occur frequently and have a multifactorial aetiology. The lowest prevalence was recorded among individuals younger than 20 years of age. As the majority of risk factors are modifiable, regular dental care could lead to the early detection of NCCLs.",
publisher = "Wiley, Hoboken",
journal = "International Dental Journal",
title = "Prevalence of non-carious cervical lesions among the general population of the Republic of Srpska, Bosnia and Herzegovina",
volume = "69",
number = "4",
pages = "281-288",
doi = "10.1111/idj.12462"
}

Zuza, A., Racić, M., Ivković, N., Krunić, J., Stojanović, N., Božović, Đ., Banković-Lazarević, D.,& Vujašković, M.. (2019). Prevalence of non-carious cervical lesions among the general population of the Republic of Srpska, Bosnia and Herzegovina. in International Dental Journal
Wiley, Hoboken., 69(4), 281-288.
https://doi.org/10.1111/idj.12462

Zuza A, Racić M, Ivković N, Krunić J, Stojanović N, Božović Đ, Banković-Lazarević D, Vujašković M. Prevalence of non-carious cervical lesions among the general population of the Republic of Srpska, Bosnia and Herzegovina. in International Dental Journal. 2019;69(4):281-288.
doi:10.1111/idj.12462 .

Zuza, Aleksandra, Racić, Maja, Ivković, Nedeljka, Krunić, Jelena, Stojanović, Nikola, Božović, Đorđe, Banković-Lazarević, Dušica, Vujašković, Mirjana, "Prevalence of non-carious cervical lesions among the general population of the Republic of Srpska, Bosnia and Herzegovina" in International Dental Journal, 69, no. 4 (2019):281-288,
https://doi.org/10.1111/idj.12462 . .

TY  - JOUR
AU  - Krunić, Jelena
AU  - Stojanović, Nikola
AU  - Đukić, Ljiljana
AU  - Roganović, Jelena
AU  - Popović, Branka
AU  - Simić, Ivana
AU  - Stojić, Dragica
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2465
AB  - ObjectivesTo evaluate local effect of gaseous ozone on bacteria in deep carious lesions after incomplete caries removal, using chlorhexidine as control, and to investigate its effect on pulp vascular endothelial growth factor (VEGF), neuronal nitric oxide synthase (nNOS), and superoxide dismutase (SOD).Materials and methodsAntibacterial effect was evaluated in 48 teeth with diagnosed deep carious lesion. After incomplete caries removal, teeth were randomly allocated into two groups regarding the cavity disinfectant used: ozone (open system) or 2% chlorhexidine. Dentin samples were analyzed for the presence of total bacteria and Lactobacillus spp. by real-time quantitative polymerase chain reaction. For evaluation of ozone effect on dental pulp, 38 intact permanent teeth indicated for pulp removal/tooth extraction were included. After cavity preparation, teeth were randomly allocated into two groups: ozone group and control group. VEGF/nNOS level and SOD activity in dental pulp were determined by enzyme-linked immunosorbent assay and spectrophotometric method, respectively.ResultsOzone application decreased number of total bacteria (p=0.001) and Lactobacillus spp. (p lt 0.001), similarly to chlorhexidine. The VEGF (p lt 0.001) and nNOS (p=0.012) levels in dental pulp after ozone application were higher, while SOD activity was lower (p=0.001) comparing to those in control pulp.ConclusionsAntibacterial effect of ozone on residual bacteria after incomplete caries removal was similar to that of 2% chlorhexidine. Effect of ozone on pulp VEGF, nNOS, and SOD indicated its biocompatibility.Clinical relevanceOzone appears as effective and biocompatible cavity disinfectant in treatment of deep carious lesions by incomplete caries removal technique.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Clinical antibacterial effectiveness and biocompatibility of gaseous ozone after incomplete caries removal
VL  - 23
IS  - 2
SP  - 785
EP  - 792
DO  - 10.1007/s00784-018-2495-x
ER  - 

@article{
author = "Krunić, Jelena and Stojanović, Nikola and Đukić, Ljiljana and Roganović, Jelena and Popović, Branka and Simić, Ivana and Stojić, Dragica",
year = "2019",
abstract = "ObjectivesTo evaluate local effect of gaseous ozone on bacteria in deep carious lesions after incomplete caries removal, using chlorhexidine as control, and to investigate its effect on pulp vascular endothelial growth factor (VEGF), neuronal nitric oxide synthase (nNOS), and superoxide dismutase (SOD).Materials and methodsAntibacterial effect was evaluated in 48 teeth with diagnosed deep carious lesion. After incomplete caries removal, teeth were randomly allocated into two groups regarding the cavity disinfectant used: ozone (open system) or 2% chlorhexidine. Dentin samples were analyzed for the presence of total bacteria and Lactobacillus spp. by real-time quantitative polymerase chain reaction. For evaluation of ozone effect on dental pulp, 38 intact permanent teeth indicated for pulp removal/tooth extraction were included. After cavity preparation, teeth were randomly allocated into two groups: ozone group and control group. VEGF/nNOS level and SOD activity in dental pulp were determined by enzyme-linked immunosorbent assay and spectrophotometric method, respectively.ResultsOzone application decreased number of total bacteria (p=0.001) and Lactobacillus spp. (p lt 0.001), similarly to chlorhexidine. The VEGF (p lt 0.001) and nNOS (p=0.012) levels in dental pulp after ozone application were higher, while SOD activity was lower (p=0.001) comparing to those in control pulp.ConclusionsAntibacterial effect of ozone on residual bacteria after incomplete caries removal was similar to that of 2% chlorhexidine. Effect of ozone on pulp VEGF, nNOS, and SOD indicated its biocompatibility.Clinical relevanceOzone appears as effective and biocompatible cavity disinfectant in treatment of deep carious lesions by incomplete caries removal technique.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Clinical antibacterial effectiveness and biocompatibility of gaseous ozone after incomplete caries removal",
volume = "23",
number = "2",
pages = "785-792",
doi = "10.1007/s00784-018-2495-x"
}

Krunić, J., Stojanović, N., Đukić, L., Roganović, J., Popović, B., Simić, I.,& Stojić, D.. (2019). Clinical antibacterial effectiveness and biocompatibility of gaseous ozone after incomplete caries removal. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 23(2), 785-792.
https://doi.org/10.1007/s00784-018-2495-x

Krunić J, Stojanović N, Đukić L, Roganović J, Popović B, Simić I, Stojić D. Clinical antibacterial effectiveness and biocompatibility of gaseous ozone after incomplete caries removal. in Clinical Oral Investigations. 2019;23(2):785-792.
doi:10.1007/s00784-018-2495-x .

Krunić, Jelena, Stojanović, Nikola, Đukić, Ljiljana, Roganović, Jelena, Popović, Branka, Simić, Ivana, Stojić, Dragica, "Clinical antibacterial effectiveness and biocompatibility of gaseous ozone after incomplete caries removal" in Clinical Oral Investigations, 23, no. 2 (2019):785-792,
https://doi.org/10.1007/s00784-018-2495-x . .

TY  - JOUR
AU  - Stojanović, Nikola
AU  - Krunić, Jelena
AU  - Mladenović, Irena
AU  - Stojanović, Zorica
AU  - Apostolska, Sonja
AU  - Živković, Slavoljub
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2354
AB  - Introduction/Objective The aim of this study was to determine clinical and radiographic periapical healing of teeth with apical periodontitis treated with different formulations of calcium hydroxide (CH) - paste (CH-paste) and gutta-percha points (CH-GP) - as well as those of chlorhexidine (CHX) - gel (CHXgel) and gutta-percha points (CHX-GP) -12 months after therapy. Methods Eighty patients with chronic apical periodontitis were randomly allocated to four treatment groups according to the intracanal medicament used: CH-paste, CH-GP, CHX-gel, and CHX-GP group. Seventy-eight patients were analyzed clinically and radiographically 12 months postoperatively. The periapical index (PAI) was used for the radiographic evaluation of treatment. Results Overall outcome was classified according to radiographic evaluation only, since clinical success was observed in all the patients. In all the groups, significant reduction in PAI scores was observed (p  lt  0.001). The proportions of healed teeth (PAI ≤ 2) were 73.7%, 60%, 68.4%, and 65% in CH-paste, CH-GP, CHX-gel and CHX-GP group, respectively, with no significant differences between the groups. Conclusion The results suggest that there are no differences between investigated CH- and CHX-delivery systems regarding treatment outcome of teeth with apical periodontitis.
AB  - Uvod/Cilj Cilj ovog istraživanja je bio da se ispita klinički i radiografski ishod lečenja zuba sa apeksnim periodontitisom 12 meseci posle završene terapije i primene različitih oblika kalcijum-hidroksida (KH): pasta (KH-pasta) i gutaperka poeni (KH-GP) i hlorheksidina (HH): gel (HH-gel) i gutaperka poeni (HH-GP). Metode Randomizovano je 80 ispitanika sa hroničnim periapeksnim lezijama u četiri grupe na osnovu vrste korišćenog interseansnog medikamenta: KH-pasta, KH-GP, HH-gel i HH-GP. Dvanaest meseci posle završenog lečenja pregledano je 78 ispitanika i urađeni su retroalveolarni snimci. Za procenu radiografskog uspeha lečenja korišćen je periapikalni indeks (PI). Rezultati Ishod lečenja je klasifikovan na osnovu radiološkog nalaza jer je kod svih ispitanika zabeležen klinički uspeh lečenja. U svim ispitivanim grupama je zabeleženo značajno smanjenje vrednosti PI (p  lt  0,001). Izlečenje (PI ≤ 2) uočeno je kod 73,3% zuba u grupi KH-pasta, 60% u KH-GP grupi, 68,4% u grupi HH-gel i kod 65% zuba u grupi HH-GP, pri čemu razlike između grupa nisu bile statistički značajne. Zaključak Rezultati ovog istraživanja pokazuju da ne postoji razlika u ishodu lečenja zuba sa apeksnim periodontitisom posle primene ispitivanih oblika KH i HH.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis
T1  - Uticaj različitih oblika kalcijum-hidroksida i hlorheksidina kao interseansnih medikamenata na ishod endodontskog lečenja zuba sa hroničnim periapeksnim lezijama
VL  - 146
IS  - 3-4
SP  - 143
EP  - 148
DO  - 10.2298/SARH170221139S
ER  - 

@article{
author = "Stojanović, Nikola and Krunić, Jelena and Mladenović, Irena and Stojanović, Zorica and Apostolska, Sonja and Živković, Slavoljub",
year = "2018",
abstract = "Introduction/Objective The aim of this study was to determine clinical and radiographic periapical healing of teeth with apical periodontitis treated with different formulations of calcium hydroxide (CH) - paste (CH-paste) and gutta-percha points (CH-GP) - as well as those of chlorhexidine (CHX) - gel (CHXgel) and gutta-percha points (CHX-GP) -12 months after therapy. Methods Eighty patients with chronic apical periodontitis were randomly allocated to four treatment groups according to the intracanal medicament used: CH-paste, CH-GP, CHX-gel, and CHX-GP group. Seventy-eight patients were analyzed clinically and radiographically 12 months postoperatively. The periapical index (PAI) was used for the radiographic evaluation of treatment. Results Overall outcome was classified according to radiographic evaluation only, since clinical success was observed in all the patients. In all the groups, significant reduction in PAI scores was observed (p  lt  0.001). The proportions of healed teeth (PAI ≤ 2) were 73.7%, 60%, 68.4%, and 65% in CH-paste, CH-GP, CHX-gel and CHX-GP group, respectively, with no significant differences between the groups. Conclusion The results suggest that there are no differences between investigated CH- and CHX-delivery systems regarding treatment outcome of teeth with apical periodontitis., Uvod/Cilj Cilj ovog istraživanja je bio da se ispita klinički i radiografski ishod lečenja zuba sa apeksnim periodontitisom 12 meseci posle završene terapije i primene različitih oblika kalcijum-hidroksida (KH): pasta (KH-pasta) i gutaperka poeni (KH-GP) i hlorheksidina (HH): gel (HH-gel) i gutaperka poeni (HH-GP). Metode Randomizovano je 80 ispitanika sa hroničnim periapeksnim lezijama u četiri grupe na osnovu vrste korišćenog interseansnog medikamenta: KH-pasta, KH-GP, HH-gel i HH-GP. Dvanaest meseci posle završenog lečenja pregledano je 78 ispitanika i urađeni su retroalveolarni snimci. Za procenu radiografskog uspeha lečenja korišćen je periapikalni indeks (PI). Rezultati Ishod lečenja je klasifikovan na osnovu radiološkog nalaza jer je kod svih ispitanika zabeležen klinički uspeh lečenja. U svim ispitivanim grupama je zabeleženo značajno smanjenje vrednosti PI (p  lt  0,001). Izlečenje (PI ≤ 2) uočeno je kod 73,3% zuba u grupi KH-pasta, 60% u KH-GP grupi, 68,4% u grupi HH-gel i kod 65% zuba u grupi HH-GP, pri čemu razlike između grupa nisu bile statistički značajne. Zaključak Rezultati ovog istraživanja pokazuju da ne postoji razlika u ishodu lečenja zuba sa apeksnim periodontitisom posle primene ispitivanih oblika KH i HH.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis, Uticaj različitih oblika kalcijum-hidroksida i hlorheksidina kao interseansnih medikamenata na ishod endodontskog lečenja zuba sa hroničnim periapeksnim lezijama",
volume = "146",
number = "3-4",
pages = "143-148",
doi = "10.2298/SARH170221139S"
}

Stojanović, N., Krunić, J., Mladenović, I., Stojanović, Z., Apostolska, S.,& Živković, S.. (2018). Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 146(3-4), 143-148.
https://doi.org/10.2298/SARH170221139S

Stojanović N, Krunić J, Mladenović I, Stojanović Z, Apostolska S, Živković S. Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis. in Srpski arhiv za celokupno lekarstvo. 2018;146(3-4):143-148.
doi:10.2298/SARH170221139S .

Stojanović, Nikola, Krunić, Jelena, Mladenović, Irena, Stojanović, Zorica, Apostolska, Sonja, Živković, Slavoljub, "Influence of different forms of calcium hydroxide and chlorhexidine intracanal medicaments on the outcome of endodontic treatment of teeth with chronic apical periodontitis" in Srpski arhiv za celokupno lekarstvo, 146, no. 3-4 (2018):143-148,
https://doi.org/10.2298/SARH170221139S . .

TY  - JOUR
AU  - Stojanović, Nikola
AU  - Krunić, Jelena
AU  - Popović, Branka
AU  - Stojičić, Sonja
AU  - Živković, Slavoljub
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1912
AB  - Introduction Because apical periodontitis is recognizably an infectious disease, elimination or reduction of intracanal bacteria is of utmost importance for optimum treatment outcome. Objective The prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals was studied Also, the effect of endodontic therapy by using intracanal medicaments, calcium hydroxide paste (CH) or gutta-percha points containing calcium hydroxide (CH-GP) or chlorhexidine (CHX-GP) on these microorganisms was assessed by polymerase chain reaction (PCR) assay. Methods Fifty-one patients with chronic apical periodontitis were randomly allocated in one of the following groups according to the intracanal medicament used: CH, CH-GP and CHX-GP group. Bacterial samples were taken upon access (S1), after chemomechanical instrumentation (S2) and after 15-day medication (S3). PCR assay was used to detect the presence of selected bacteria. Results E. faecalis was detected in 49% (25/51) and P. gingivalis in 17.6% (9/51) of the samples. Samples which showed no bacterial presence at S1 were excluded from further analysis. Overall analysis of all 29 samples revealed significant differences between S1 and S2 (p lt 0.001), S2 and S3 (p lt 0.05), and S1 and S3 (p lt 0.001). When distinction was made between the intracanal medications, there was a significant difference in the number of PCR positive samples between S1 and S2, S1 and S3, but not between S2 and S3 samples. Conclusion E. faecalis is more prevalent than P. gingivalis in primary endodontic infection. Intracanal medication in conduction with instrumentation and irrigation efficiently eliminates E. faecalis and P. gingivalis from infected root canals.
AB  - Uvod Budući da je apeksni parodontitis oboljenje koje nastaje usled postojanja infekcije, za postizanje optimalnog ishoda lečenja najznačajnije je uklanjanje bakterija iz kanala korena zuba ili barem smanjenje njihovog broja. Cilj rada Cilj ovog rada je bio da se ispita prevalencija bakterija Enterococcus faecalis i Porphyromonas gingivalis u inficiranim kanalima korena zuba i ustanovi efekat endodontskog lečenja primenom intrakanalnih medikamenata - kalcijum-hidroksidne suspenzije (CH), gutaperka-poena na bazi kalcijum-hidroksida (CH-GP) ili gutaperka-poena na bazi hlorheksidina (CHX-GP) - na ove mikroorganizme metodom lančane reakcije polimerizacije (PCR). Metode rada Istraživanjem je obuhvaćena 51 osoba koja je imala zub s hroničnim apeksnim parodontitisom. Ispitanici su metodom slučajnog uzorka svrstani u tri grupe u zavisnosti od vrste primenjenog intrakanalnog medikamenta (CH, CH-GP i CHX-GP). Bakterijski uzorci iz kanala korena sakupljani su pri inicijalnom ulasku u kanal korena (S1), posle hemomehaničke obrade (S2) i posle petnaestodnevnog lečenja (S3). PCR analiza je korišćena za određivanje prisustva ispitivanih bakterija. Rezultati E. faecalis je izolovan iz 25 (49%) uzoraka, a P. gingivalis iz devet (17,6%). Uzorci u kojima nisu nađene bakterije u S1 fazi isključeni su iz dalje analize. Analiza svih 29 uzoraka je ukazala na statistički značajnu razliku između S1 i S2 uzoraka (p lt 0,001), S2 i S3 (p lt 0,05) i S1 i S3 (p lt 0,001). Kada se uzme u obzir vrsta intrakanalnog medikamenta, statistički značajna razlika u broju PCR-pozitivnih uzoraka zabeležena je između S1 i S2, S1 i S3, ali ne i između S2 i S3. Zaključak U primarnoj endodontskoj infekciji E. faecalis se češće javlja od P. gingivalis. Intrakanalna medikacija zajedno s instrumentacijom i irigacijom efikasno uklanja E. faecalis i P. gingivalis iz inficiranih kanala korena.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study
T1  - Prevalencija bakterija Enterococcus faecalis i Porphyromonas gingivalis u inficiranim kanalima korena zuba i njihova osetljivost na endodontsko lečenje - molekularna studija
VL  - 142
IS  - 9-10
SP  - 535
EP  - 541
DO  - 10.2298/SARH1410535S
ER  - 

@article{
author = "Stojanović, Nikola and Krunić, Jelena and Popović, Branka and Stojičić, Sonja and Živković, Slavoljub",
year = "2014",
abstract = "Introduction Because apical periodontitis is recognizably an infectious disease, elimination or reduction of intracanal bacteria is of utmost importance for optimum treatment outcome. Objective The prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals was studied Also, the effect of endodontic therapy by using intracanal medicaments, calcium hydroxide paste (CH) or gutta-percha points containing calcium hydroxide (CH-GP) or chlorhexidine (CHX-GP) on these microorganisms was assessed by polymerase chain reaction (PCR) assay. Methods Fifty-one patients with chronic apical periodontitis were randomly allocated in one of the following groups according to the intracanal medicament used: CH, CH-GP and CHX-GP group. Bacterial samples were taken upon access (S1), after chemomechanical instrumentation (S2) and after 15-day medication (S3). PCR assay was used to detect the presence of selected bacteria. Results E. faecalis was detected in 49% (25/51) and P. gingivalis in 17.6% (9/51) of the samples. Samples which showed no bacterial presence at S1 were excluded from further analysis. Overall analysis of all 29 samples revealed significant differences between S1 and S2 (p lt 0.001), S2 and S3 (p lt 0.05), and S1 and S3 (p lt 0.001). When distinction was made between the intracanal medications, there was a significant difference in the number of PCR positive samples between S1 and S2, S1 and S3, but not between S2 and S3 samples. Conclusion E. faecalis is more prevalent than P. gingivalis in primary endodontic infection. Intracanal medication in conduction with instrumentation and irrigation efficiently eliminates E. faecalis and P. gingivalis from infected root canals., Uvod Budući da je apeksni parodontitis oboljenje koje nastaje usled postojanja infekcije, za postizanje optimalnog ishoda lečenja najznačajnije je uklanjanje bakterija iz kanala korena zuba ili barem smanjenje njihovog broja. Cilj rada Cilj ovog rada je bio da se ispita prevalencija bakterija Enterococcus faecalis i Porphyromonas gingivalis u inficiranim kanalima korena zuba i ustanovi efekat endodontskog lečenja primenom intrakanalnih medikamenata - kalcijum-hidroksidne suspenzije (CH), gutaperka-poena na bazi kalcijum-hidroksida (CH-GP) ili gutaperka-poena na bazi hlorheksidina (CHX-GP) - na ove mikroorganizme metodom lančane reakcije polimerizacije (PCR). Metode rada Istraživanjem je obuhvaćena 51 osoba koja je imala zub s hroničnim apeksnim parodontitisom. Ispitanici su metodom slučajnog uzorka svrstani u tri grupe u zavisnosti od vrste primenjenog intrakanalnog medikamenta (CH, CH-GP i CHX-GP). Bakterijski uzorci iz kanala korena sakupljani su pri inicijalnom ulasku u kanal korena (S1), posle hemomehaničke obrade (S2) i posle petnaestodnevnog lečenja (S3). PCR analiza je korišćena za određivanje prisustva ispitivanih bakterija. Rezultati E. faecalis je izolovan iz 25 (49%) uzoraka, a P. gingivalis iz devet (17,6%). Uzorci u kojima nisu nađene bakterije u S1 fazi isključeni su iz dalje analize. Analiza svih 29 uzoraka je ukazala na statistički značajnu razliku između S1 i S2 uzoraka (p lt 0,001), S2 i S3 (p lt 0,05) i S1 i S3 (p lt 0,001). Kada se uzme u obzir vrsta intrakanalnog medikamenta, statistički značajna razlika u broju PCR-pozitivnih uzoraka zabeležena je između S1 i S2, S1 i S3, ali ne i između S2 i S3. Zaključak U primarnoj endodontskoj infekciji E. faecalis se češće javlja od P. gingivalis. Intrakanalna medikacija zajedno s instrumentacijom i irigacijom efikasno uklanja E. faecalis i P. gingivalis iz inficiranih kanala korena.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study, Prevalencija bakterija Enterococcus faecalis i Porphyromonas gingivalis u inficiranim kanalima korena zuba i njihova osetljivost na endodontsko lečenje - molekularna studija",
volume = "142",
number = "9-10",
pages = "535-541",
doi = "10.2298/SARH1410535S"
}

Stojanović, N., Krunić, J., Popović, B., Stojičić, S.,& Živković, S.. (2014). Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 142(9-10), 535-541.
https://doi.org/10.2298/SARH1410535S

Stojanović N, Krunić J, Popović B, Stojičić S, Živković S. Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study. in Srpski arhiv za celokupno lekarstvo. 2014;142(9-10):535-541.
doi:10.2298/SARH1410535S .

Stojanović, Nikola, Krunić, Jelena, Popović, Branka, Stojičić, Sonja, Živković, Slavoljub, "Prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals and their susceptibility to endodontic treatment procedures: A molecular study" in Srpski arhiv za celokupno lekarstvo, 142, no. 9-10 (2014):535-541,
https://doi.org/10.2298/SARH1410535S . .

TY  - JOUR
AU  - Davidović, Lado
AU  - Stojanović, Nikola
AU  - Krunić, Jelena
AU  - Živković, Slavoljub
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1810
AB  - Introduction. Lack of proper adhesion is one of the most common problems in modern restorative dentistry and the main cause of the occurrence of microcracks at the interface between materials and hard dental tissue. The aim of this study was to assess the quality of bond between two types of glass-ionomer cement (GIC) class V restorations and hard dental tissues by SEM. Materials and Methods. This clinical study included 20 intact teeth (premolars and molars) recently extracted for orthodontic reasons in patients of both genders and different ages. Class V cavity with rounded walls was prepared on vestibular and oral surfaces of all teeth (3x2x2 mm). Conventional GIC Fuji II was applied on vestibular surface of teeth whereas on oral surface resin-reinforced glass ionomer Fuji II LC was placed. The bond between fillings and hard dental tissue was assessed by SEM. Results. Both materials showed microcracks, however, microleakage was lower with Fuji II LC than with Fuji II. Microcracks were observed in 65% of cases (13 restorations) restored with GIC Fuji II and 35% (7 fillings) restored with GIC Fuji II LC. The size of microcracks for Fuji II LC was 9 μm while this value for Fuji II was 17 μm. The difference was statistically significant. Conclusion. Better bond between material and hard dental tissue was achieved with the material of new generation, resin modified GIC.
AB  - Uvod. Nedostatak odgovarajuće adhezivnosti je jedan od najčešćih problema u savremenoj restaurativnoj stomatologiji i glavni uzrok nastanka mikropukotine na spoju materijala i tvrdih zubnih tkiva. Cilj ovog rada je bio da se SEM (skening-elektronska mikroskopija) analizom proveri kvalitet veze dve vrste glasjonomercementnih (GJC) restauracija za tvrda zubna tkiva kod kaviteta V klase. Materijal i metode rada. Kliničko istraživanje je obuhvatilo 20 sveže ekstrahovanih intaktnih zuba (premolari i molari), odstranjenih iz ortodontskih razloga kod pacijenata oba pola i različite starosti. Na svim zubima su sa vestibularne i oralne strane urađene jednopovršinske preparacije V klase adhezivnog tipa sa zaobljenim zidovima kaviteta (dimenzija 3×2×2 mm). Sa vestibularne strane primenjen je klasični GJC Fuji II, a sa oralne smolom ojačani GJC Fuji II LC. Kvalitet veze između ispuna i zubnih tkiva je procenjivan SEM analizom. Rezultati. Dobijeni nalazi su pokazali da je kod oba materijala zabeležena mikropukotina i da je stepen mikrocurenja kod Fuji II LC bio manji nego kod Fuji II. Kod zuba restaurisanih sa GJC Fuji II mikropukotina je uočena u 65% slučajeva (13 ispuna), a kod zuba restaurisanih sa GJC Fuji II LC u 35% slučajeva (sedam ispuna). SEM analizom je utvrđena srednja vrednost mikropukotine za Fuji II LC od 9 µm, dok je ova vrednost za Fuji II bila 17 µm. Razlika je bila statistički značajna. Zaključak. Na osnovu rezultata istraživanja može se zaključiti da je bolji kvalitet veze ostvaren primenom materijala novije generacije, odnosno primenom GJC modifikovanih smolom.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Scanning electron microscopy analysis of adhesive bond of glass-ionomer cement restorations
T1  - SEM analiza kvaliteta adhezivne veze glasjonomercementnih restauracija
VL  - 60
IS  - 2
SP  - 85
EP  - 92
DO  - 10.2298/SGS1302085D
ER  - 

@article{
author = "Davidović, Lado and Stojanović, Nikola and Krunić, Jelena and Živković, Slavoljub",
year = "2013",
abstract = "Introduction. Lack of proper adhesion is one of the most common problems in modern restorative dentistry and the main cause of the occurrence of microcracks at the interface between materials and hard dental tissue. The aim of this study was to assess the quality of bond between two types of glass-ionomer cement (GIC) class V restorations and hard dental tissues by SEM. Materials and Methods. This clinical study included 20 intact teeth (premolars and molars) recently extracted for orthodontic reasons in patients of both genders and different ages. Class V cavity with rounded walls was prepared on vestibular and oral surfaces of all teeth (3x2x2 mm). Conventional GIC Fuji II was applied on vestibular surface of teeth whereas on oral surface resin-reinforced glass ionomer Fuji II LC was placed. The bond between fillings and hard dental tissue was assessed by SEM. Results. Both materials showed microcracks, however, microleakage was lower with Fuji II LC than with Fuji II. Microcracks were observed in 65% of cases (13 restorations) restored with GIC Fuji II and 35% (7 fillings) restored with GIC Fuji II LC. The size of microcracks for Fuji II LC was 9 μm while this value for Fuji II was 17 μm. The difference was statistically significant. Conclusion. Better bond between material and hard dental tissue was achieved with the material of new generation, resin modified GIC., Uvod. Nedostatak odgovarajuće adhezivnosti je jedan od najčešćih problema u savremenoj restaurativnoj stomatologiji i glavni uzrok nastanka mikropukotine na spoju materijala i tvrdih zubnih tkiva. Cilj ovog rada je bio da se SEM (skening-elektronska mikroskopija) analizom proveri kvalitet veze dve vrste glasjonomercementnih (GJC) restauracija za tvrda zubna tkiva kod kaviteta V klase. Materijal i metode rada. Kliničko istraživanje je obuhvatilo 20 sveže ekstrahovanih intaktnih zuba (premolari i molari), odstranjenih iz ortodontskih razloga kod pacijenata oba pola i različite starosti. Na svim zubima su sa vestibularne i oralne strane urađene jednopovršinske preparacije V klase adhezivnog tipa sa zaobljenim zidovima kaviteta (dimenzija 3×2×2 mm). Sa vestibularne strane primenjen je klasični GJC Fuji II, a sa oralne smolom ojačani GJC Fuji II LC. Kvalitet veze između ispuna i zubnih tkiva je procenjivan SEM analizom. Rezultati. Dobijeni nalazi su pokazali da je kod oba materijala zabeležena mikropukotina i da je stepen mikrocurenja kod Fuji II LC bio manji nego kod Fuji II. Kod zuba restaurisanih sa GJC Fuji II mikropukotina je uočena u 65% slučajeva (13 ispuna), a kod zuba restaurisanih sa GJC Fuji II LC u 35% slučajeva (sedam ispuna). SEM analizom je utvrđena srednja vrednost mikropukotine za Fuji II LC od 9 µm, dok je ova vrednost za Fuji II bila 17 µm. Razlika je bila statistički značajna. Zaključak. Na osnovu rezultata istraživanja može se zaključiti da je bolji kvalitet veze ostvaren primenom materijala novije generacije, odnosno primenom GJC modifikovanih smolom.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Scanning electron microscopy analysis of adhesive bond of glass-ionomer cement restorations, SEM analiza kvaliteta adhezivne veze glasjonomercementnih restauracija",
volume = "60",
number = "2",
pages = "85-92",
doi = "10.2298/SGS1302085D"
}

Davidović, L., Stojanović, N., Krunić, J.,& Živković, S.. (2013). Scanning electron microscopy analysis of adhesive bond of glass-ionomer cement restorations. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 60(2), 85-92.
https://doi.org/10.2298/SGS1302085D

Davidović L, Stojanović N, Krunić J, Živković S. Scanning electron microscopy analysis of adhesive bond of glass-ionomer cement restorations. in Stomatološki glasnik Srbije. 2013;60(2):85-92.
doi:10.2298/SGS1302085D .

Davidović, Lado, Stojanović, Nikola, Krunić, Jelena, Živković, Slavoljub, "Scanning electron microscopy analysis of adhesive bond of glass-ionomer cement restorations" in Stomatološki glasnik Srbije, 60, no. 2 (2013):85-92,
https://doi.org/10.2298/SGS1302085D . .

TY  - JOUR
AU  - Kulić, Ljiljana
AU  - Nogo-Živanović, Dajana
AU  - Krunić, Jelena
AU  - Vujašković, Mirjana
AU  - Stojanović, Nikola
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1675
AB  - Introduction. The main goal of obturation is prevention of reinfection of the root canal system and consequently appearance of periapical lesion. Epidemiological studies have confirmed high prevalence of periapical lesions in endodontically treated teeth with inadequate root canal fillings. The aim of this study was to assess the quality of root canal fillings in teeth treated at students' practical sessions. Iatrogenic errors during endodontic interventions were also assessed. Methods. Two hundred dental records of the patients treated by students in the study program Dentistry at the School of Medicine in Foca during the academic year 2010/2011 were randomly chosen. The length and homogeneity of the fillings or the presence of iatrogenic errors were recorded. A root canal filling was considered adequate if it had correct length and homogeneity in the absence of iatrogenic errors. Two students' curricula V1 and V2 were evaluated for the treatment outcome. Results. Out of 128 endodontically treated teeth, adequate length of the canal filling to the physiological apex was observed in 57% of teeth, homogeneity in 78.9%, while both of these criteria were satisfied in 66 teeth (51.6%). Better quality of root canal fillings was achieved by students of the study curricula V2 and the difference between these two programs was significant (p lt 0.05). Better quality of root canal fillings in both study programs was recorded for incisors and canines as compared to premolars. Conclusion. The quality of endodontic treatment performed by students was considered adequate in 51.6% of cases. The type of curriculum for endodontic course had a significant impact on the quality of endodontic treatment performed by students.
AB  - Uvod. Opturacija kanala korena zuba vrši se radi prevencije ponovne infekcije kanalnog sistema i obezbeđivanja uslova za efikasno ozdravljenje periapeksnog tkiva. Epidemiološke studije su ukazale na visoku stopu prevalencije periapeksnih promena kod endodontski lečenih zuba sa neodgovarajućim punjenjem kanala. Cilj rada bio je da se proveri kvalitet punjenja kanala korena endodontski lečenih zuba na studentskim vežbama i ustanove lekarske greške nastale tokom endodontske intervencije. Materijal i metode rada. Za potrebe istraživanja metodom slučajnog uzorka odabrano je 200 kartona pacijenata kojima je vršen endodontski tretman na studentskim vežbama koje su u okviru studijskog programa Stomatologija izvođene na Medicinskom fakultetu u Foči tokom 2010/2011. školske godine. Parametri posmatranja bili su dužina i homogenost punjenja kanala i postojanje lekarskih grešaka tokom zahvata. Adekvatnim se smatralo punjenje kanala koje ima odgovarajuću dužinu i homogenost i bez lekarskih grešaka. Analizirana su dva studentska programa iz oblasti endodoncije (V1 i V2) i utvrđen ishod lečenja obolelih zuba. Rezultati. Od 128 endodontski lečenih zuba, odgovarajuća dužina punjenja kanala do fiziološkog suženja utvrđena je u 57% uzoraka, homogenost u 78,9% uzoraka, dok su oba ova kriterijuma bila zadovoljena kod ukupno 66 zuba (51,6%). Kvalitetnije punjenje kanala korena uradili su studenti programa V2, a razlika između dva studentska programa bila je statistički značajna (p lt 0,05). Kvalitetna opturacija kanala u oba studijska programa zabeležena je kod sekutića i očnjaka u odnosu na premolare. Zaključak. Kvalitet endodontskog lečenja na studentskim vežbama bio je odgovarajući u nešto više od polovine slučajeva. Kurikulum iz oblasti endodoncije ima značajan uticaj na kvalitet endodontskog lečenja na studentskim vežbama.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Radiological assessment of the quality of root canal fillings in teeth endodontically treated at students' practical sessions
T1  - Radiološka procena kvaliteta punjenja kanala korena endodontski lečenih zuba na studentskim vežbama
VL  - 58
IS  - 3
SP  - 139
EP  - 146
DO  - 10.2298/SGS1103139K
ER  - 

@article{
author = "Kulić, Ljiljana and Nogo-Živanović, Dajana and Krunić, Jelena and Vujašković, Mirjana and Stojanović, Nikola",
year = "2011",
abstract = "Introduction. The main goal of obturation is prevention of reinfection of the root canal system and consequently appearance of periapical lesion. Epidemiological studies have confirmed high prevalence of periapical lesions in endodontically treated teeth with inadequate root canal fillings. The aim of this study was to assess the quality of root canal fillings in teeth treated at students' practical sessions. Iatrogenic errors during endodontic interventions were also assessed. Methods. Two hundred dental records of the patients treated by students in the study program Dentistry at the School of Medicine in Foca during the academic year 2010/2011 were randomly chosen. The length and homogeneity of the fillings or the presence of iatrogenic errors were recorded. A root canal filling was considered adequate if it had correct length and homogeneity in the absence of iatrogenic errors. Two students' curricula V1 and V2 were evaluated for the treatment outcome. Results. Out of 128 endodontically treated teeth, adequate length of the canal filling to the physiological apex was observed in 57% of teeth, homogeneity in 78.9%, while both of these criteria were satisfied in 66 teeth (51.6%). Better quality of root canal fillings was achieved by students of the study curricula V2 and the difference between these two programs was significant (p lt 0.05). Better quality of root canal fillings in both study programs was recorded for incisors and canines as compared to premolars. Conclusion. The quality of endodontic treatment performed by students was considered adequate in 51.6% of cases. The type of curriculum for endodontic course had a significant impact on the quality of endodontic treatment performed by students., Uvod. Opturacija kanala korena zuba vrši se radi prevencije ponovne infekcije kanalnog sistema i obezbeđivanja uslova za efikasno ozdravljenje periapeksnog tkiva. Epidemiološke studije su ukazale na visoku stopu prevalencije periapeksnih promena kod endodontski lečenih zuba sa neodgovarajućim punjenjem kanala. Cilj rada bio je da se proveri kvalitet punjenja kanala korena endodontski lečenih zuba na studentskim vežbama i ustanove lekarske greške nastale tokom endodontske intervencije. Materijal i metode rada. Za potrebe istraživanja metodom slučajnog uzorka odabrano je 200 kartona pacijenata kojima je vršen endodontski tretman na studentskim vežbama koje su u okviru studijskog programa Stomatologija izvođene na Medicinskom fakultetu u Foči tokom 2010/2011. školske godine. Parametri posmatranja bili su dužina i homogenost punjenja kanala i postojanje lekarskih grešaka tokom zahvata. Adekvatnim se smatralo punjenje kanala koje ima odgovarajuću dužinu i homogenost i bez lekarskih grešaka. Analizirana su dva studentska programa iz oblasti endodoncije (V1 i V2) i utvrđen ishod lečenja obolelih zuba. Rezultati. Od 128 endodontski lečenih zuba, odgovarajuća dužina punjenja kanala do fiziološkog suženja utvrđena je u 57% uzoraka, homogenost u 78,9% uzoraka, dok su oba ova kriterijuma bila zadovoljena kod ukupno 66 zuba (51,6%). Kvalitetnije punjenje kanala korena uradili su studenti programa V2, a razlika između dva studentska programa bila je statistički značajna (p lt 0,05). Kvalitetna opturacija kanala u oba studijska programa zabeležena je kod sekutića i očnjaka u odnosu na premolare. Zaključak. Kvalitet endodontskog lečenja na studentskim vežbama bio je odgovarajući u nešto više od polovine slučajeva. Kurikulum iz oblasti endodoncije ima značajan uticaj na kvalitet endodontskog lečenja na studentskim vežbama.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Radiological assessment of the quality of root canal fillings in teeth endodontically treated at students' practical sessions, Radiološka procena kvaliteta punjenja kanala korena endodontski lečenih zuba na studentskim vežbama",
volume = "58",
number = "3",
pages = "139-146",
doi = "10.2298/SGS1103139K"
}

Kulić, L., Nogo-Živanović, D., Krunić, J., Vujašković, M.,& Stojanović, N.. (2011). Radiological assessment of the quality of root canal fillings in teeth endodontically treated at students' practical sessions. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 58(3), 139-146.
https://doi.org/10.2298/SGS1103139K

Kulić L, Nogo-Živanović D, Krunić J, Vujašković M, Stojanović N. Radiological assessment of the quality of root canal fillings in teeth endodontically treated at students' practical sessions. in Stomatološki glasnik Srbije. 2011;58(3):139-146.
doi:10.2298/SGS1103139K .

Kulić, Ljiljana, Nogo-Živanović, Dajana, Krunić, Jelena, Vujašković, Mirjana, Stojanović, Nikola, "Radiological assessment of the quality of root canal fillings in teeth endodontically treated at students' practical sessions" in Stomatološki glasnik Srbije, 58, no. 3 (2011):139-146,
https://doi.org/10.2298/SGS1103139K . .

TY  - JOUR
AU  - Cicmil, Smiljka
AU  - Stojanović, Nikola
AU  - Krunić, Jelena
AU  - Vukotić, Olivera
AU  - Čakić, Saša
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1548
AB  - Introduction. It has been known that periodontitis is one of the most common oral diseases in patients having diabetes mellitus (DM). The aim of this study was to examine the influence of glycosylated hemoglobin (HbA1c) level and the level of oral hygiene on periodontal status of patients suffering from DM. Material and Methods. The research included 50 people with type 2 DM randomly selected. Based on values of HbA1c, patients were divided into two groups: well controlled DM (HbA1c≤8.5%) and poorly controlled DM (HbA1c>8.5%). Patients with poorly and well controlled DM were further grouped into subgroups depending on the level of oral hygiene. For each patient, during the clinical examination, periodontal parameters were determined: plaque index (PI), sulcus bleeding index (SBI), the level of junctional epithelium (LJE) and periodontal pocket depth (PPD). Results. The results showed that patients with well controlled disease and good oral hygiene had lower values of the examined periodontal parameters (SBI and PPD) then patients with poorly controlled DM and worse oral hygiene (p lt 0.01 for SBI, p lt 0.05 for PPD). Conclusion. The results of this study indicate the important role of oral hygiene for periodontal status of patients with DM.
AB  - Uvod. Parodontopatija je jedno od najčešćih oboljenja oralne regije kod osoba obolelih od dijabetes melitusa (DM). Cilj ovog istraživanja je bio da se ispita uticaj nivoa glikoziliranog hemoglobina (HbA1c) i stepena oralne higijene na stanje parodoncijuma bolesnika sa DM. Materijal i metode rada. Ispitano je 50 osoba sa DM tip 2 koje su odabrane metodom slučajnog uzorka. Na osnovu vrednosti HbA1c, ispitanici su svrstani u dve grupe: prvu grupu su činili bolesnici koji su dobro kontrolisali DM (HbA1c≤8,5%), a drugu bolesnici s loše kontrolisanim DM (HbA1c>8,5%). Ispitanici dve grupe su dalje podeljeni u podgrupe u zavisnosti od stepena oralne higijene. Svakom bolesniku su prilikom kliničkog pregleda određene vrednosti parodontalnih parametara: plak-indeksa (PI), indeksa krvarenja gingive (IKG), nivoa pripojnog epitela (NPE) i dubine parodontalnog džepa (DPDŽ). Rezultati. Dobijeni rezultati su pokazali da su kod bolesnika sa dobro kontrolisanim oboljenjem i dobrom oralnom higijenom vrednosti ispitivanih parodontalnih parametara (IKG i NPE) niže nego kod bolesnika s loše kontrolisanim DM i lošijom oralnom higijenom (p lt 0,01 za IKG; p lt 0,05 za NPE). Zaključak. Rezultati ovog istraživanja ukazuju na značajnu ulogu oralne higijene na stanje parodoncijuma osoba sa DM.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Periodontal status in patients suffering from diabetes mellitus in relations to glycosylated hemoglobin level and the level of oral hygiene
T1  - Stanje parodoncijuma osoba obolelih od dijabetes melitusa u odnosu na nivo glikoziliranog hemoglobina i oralnu higijenu
VL  - 57
IS  - 3
SP  - 129
EP  - 133
DO  - 10.2298/SGS1003129C
ER  - 

@article{
author = "Cicmil, Smiljka and Stojanović, Nikola and Krunić, Jelena and Vukotić, Olivera and Čakić, Saša",
year = "2010",
abstract = "Introduction. It has been known that periodontitis is one of the most common oral diseases in patients having diabetes mellitus (DM). The aim of this study was to examine the influence of glycosylated hemoglobin (HbA1c) level and the level of oral hygiene on periodontal status of patients suffering from DM. Material and Methods. The research included 50 people with type 2 DM randomly selected. Based on values of HbA1c, patients were divided into two groups: well controlled DM (HbA1c≤8.5%) and poorly controlled DM (HbA1c>8.5%). Patients with poorly and well controlled DM were further grouped into subgroups depending on the level of oral hygiene. For each patient, during the clinical examination, periodontal parameters were determined: plaque index (PI), sulcus bleeding index (SBI), the level of junctional epithelium (LJE) and periodontal pocket depth (PPD). Results. The results showed that patients with well controlled disease and good oral hygiene had lower values of the examined periodontal parameters (SBI and PPD) then patients with poorly controlled DM and worse oral hygiene (p lt 0.01 for SBI, p lt 0.05 for PPD). Conclusion. The results of this study indicate the important role of oral hygiene for periodontal status of patients with DM., Uvod. Parodontopatija je jedno od najčešćih oboljenja oralne regije kod osoba obolelih od dijabetes melitusa (DM). Cilj ovog istraživanja je bio da se ispita uticaj nivoa glikoziliranog hemoglobina (HbA1c) i stepena oralne higijene na stanje parodoncijuma bolesnika sa DM. Materijal i metode rada. Ispitano je 50 osoba sa DM tip 2 koje su odabrane metodom slučajnog uzorka. Na osnovu vrednosti HbA1c, ispitanici su svrstani u dve grupe: prvu grupu su činili bolesnici koji su dobro kontrolisali DM (HbA1c≤8,5%), a drugu bolesnici s loše kontrolisanim DM (HbA1c>8,5%). Ispitanici dve grupe su dalje podeljeni u podgrupe u zavisnosti od stepena oralne higijene. Svakom bolesniku su prilikom kliničkog pregleda određene vrednosti parodontalnih parametara: plak-indeksa (PI), indeksa krvarenja gingive (IKG), nivoa pripojnog epitela (NPE) i dubine parodontalnog džepa (DPDŽ). Rezultati. Dobijeni rezultati su pokazali da su kod bolesnika sa dobro kontrolisanim oboljenjem i dobrom oralnom higijenom vrednosti ispitivanih parodontalnih parametara (IKG i NPE) niže nego kod bolesnika s loše kontrolisanim DM i lošijom oralnom higijenom (p lt 0,01 za IKG; p lt 0,05 za NPE). Zaključak. Rezultati ovog istraživanja ukazuju na značajnu ulogu oralne higijene na stanje parodoncijuma osoba sa DM.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Periodontal status in patients suffering from diabetes mellitus in relations to glycosylated hemoglobin level and the level of oral hygiene, Stanje parodoncijuma osoba obolelih od dijabetes melitusa u odnosu na nivo glikoziliranog hemoglobina i oralnu higijenu",
volume = "57",
number = "3",
pages = "129-133",
doi = "10.2298/SGS1003129C"
}

Cicmil, S., Stojanović, N., Krunić, J., Vukotić, O.,& Čakić, S.. (2010). Periodontal status in patients suffering from diabetes mellitus in relations to glycosylated hemoglobin level and the level of oral hygiene. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 57(3), 129-133.
https://doi.org/10.2298/SGS1003129C

Cicmil S, Stojanović N, Krunić J, Vukotić O, Čakić S. Periodontal status in patients suffering from diabetes mellitus in relations to glycosylated hemoglobin level and the level of oral hygiene. in Stomatološki glasnik Srbije. 2010;57(3):129-133.
doi:10.2298/SGS1003129C .

Cicmil, Smiljka, Stojanović, Nikola, Krunić, Jelena, Vukotić, Olivera, Čakić, Saša, "Periodontal status in patients suffering from diabetes mellitus in relations to glycosylated hemoglobin level and the level of oral hygiene" in Stomatološki glasnik Srbije, 57, no. 3 (2010):129-133,
https://doi.org/10.2298/SGS1003129C . .