TY  - JOUR
AU  - Tatić, Zoran
AU  - Stamatović, Novak
AU  - Bubalo, Marija
AU  - Jančić, Snežana
AU  - Račić, Alek
AU  - Miković, Nikola
AU  - Tatić, Natalija
AU  - Rakić, Mia
PY  - 2010
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1540
AB  - Background/Aim. Filling a bone defect with bone substitution materials is a therapy of choice, but the infiltration of connective tissue from the mucoperiostal flap may compromise a healing of bone substitutions with bony wall defects. Application of membrane as a barrier is indicated as a solution to this problem. The aim of this study was to show a pathohistological view of bone regeneration and the significance of human resorbable demineralized membrane (HRDM), 200 μ thick in bone regeneration regarding mandibular defects in an experiment on dogs. Methods. The experiment was performed on six dogs. Bone defects were created in all six dogs on the right side of the mandible after the elevation of the mucoperiostal flap. One defect was filled with human deproteinised bone (HDB), and in between HDB and soft tissue RHDM of 200 μ thick was placed. In the second defect, used as a control one, only HDB without RHDM was placed. Two dogs were sacrificed two months after the surgery, another two dogs four months after the surgery and the last two dogs six months after the surgery. After that, samples of bone tissue were taken for histopathological analysis. Results. In all the six dogs with defects treated with HDB and RHDM the level of bone regeneration was much higher in comparison with the control defects without RHDM. Conclusion. Membrane, as a cover of bony defect, is useful and benefits bone regeneration. Bony defects covered with RHDM show better bony healing despite the fact that bone regeneration was not fully complete for as long as six months after the RHDM implantation.
AB  - Uvod/Cilj. Popunjavanje koštanih defekata zamenicima kosti je terapija izbora, ali prorastanje vezivnog tkiva iz mukoperiostalnog režnja može kompromitovati sam proces zarastanja zamenika kosti sa zidovima koštanih defekata. U cilju rešavanja ovog problema indikovana je primena membrane kao barijere. Cilj ove studije bio je da se prikaže patohistološki izgled koštane regeneracije i značaj resorptivne demineralizovane membrane humanog porekla (RHDM), debljine 200 mikrona, u regeneraciji kosti kod mandibularnih defekata u eksperimentu rađenom na psima. Metode. Eksperiment je vršen na šest pasa kojima je sa desne strane donje vilice, po podizanju mukoperiostalnog režnja, pravljen koštani defekt. U jedan defekt stavljana je humana deproteinizovana kost (HDK), a između nje i mekotkivnog dela stavljana je RHDM debljine 200 mikrona. U drugi defekt, koji je služio kao kontrola, stavljena je samo HDK, bez RHDM. Dva psa žrtvovana su dva meseca nakon hirurške intervencije, dva posle četiri meseca, a preostala dva šest meseci nakon hirurške intervencije. Nakon žrtvovanja uzimani su isečci za patohistološku analizu. Rezultati. Kod svih šest pasa kod kojih je u koštani defekt ugrađena HDK i RHDM stepen koštane regeneracije bio je daleko veći u odnosu na kontrolne defekte bez RHDM. Zaključak. Membrana, kao pokrivač koštanog defekta, podesna je i poboljšava koštanu regeneraciju. Koštani defekti prekriveni RHDM pokazali su značajno bolje koštano zarastanje, mada koštana regeneracija nije bila potpuna ni šest meseci nakon njene ugradnje.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Histopathological evaluation of bone regeneration using human resorbable demineralized membrane
T1  - Uticaj resorptivne membrane humanog porekla na regeneraciju koštanog tkiva - patohistološka studija
VL  - 67
IS  - 6
SP  - 480
EP  - 486
DO  - 10.2298/VSP1006480T
ER  - 

@article{
author = "Tatić, Zoran and Stamatović, Novak and Bubalo, Marija and Jančić, Snežana and Račić, Alek and Miković, Nikola and Tatić, Natalija and Rakić, Mia",
year = "2010",
abstract = "Background/Aim. Filling a bone defect with bone substitution materials is a therapy of choice, but the infiltration of connective tissue from the mucoperiostal flap may compromise a healing of bone substitutions with bony wall defects. Application of membrane as a barrier is indicated as a solution to this problem. The aim of this study was to show a pathohistological view of bone regeneration and the significance of human resorbable demineralized membrane (HRDM), 200 μ thick in bone regeneration regarding mandibular defects in an experiment on dogs. Methods. The experiment was performed on six dogs. Bone defects were created in all six dogs on the right side of the mandible after the elevation of the mucoperiostal flap. One defect was filled with human deproteinised bone (HDB), and in between HDB and soft tissue RHDM of 200 μ thick was placed. In the second defect, used as a control one, only HDB without RHDM was placed. Two dogs were sacrificed two months after the surgery, another two dogs four months after the surgery and the last two dogs six months after the surgery. After that, samples of bone tissue were taken for histopathological analysis. Results. In all the six dogs with defects treated with HDB and RHDM the level of bone regeneration was much higher in comparison with the control defects without RHDM. Conclusion. Membrane, as a cover of bony defect, is useful and benefits bone regeneration. Bony defects covered with RHDM show better bony healing despite the fact that bone regeneration was not fully complete for as long as six months after the RHDM implantation., Uvod/Cilj. Popunjavanje koštanih defekata zamenicima kosti je terapija izbora, ali prorastanje vezivnog tkiva iz mukoperiostalnog režnja može kompromitovati sam proces zarastanja zamenika kosti sa zidovima koštanih defekata. U cilju rešavanja ovog problema indikovana je primena membrane kao barijere. Cilj ove studije bio je da se prikaže patohistološki izgled koštane regeneracije i značaj resorptivne demineralizovane membrane humanog porekla (RHDM), debljine 200 mikrona, u regeneraciji kosti kod mandibularnih defekata u eksperimentu rađenom na psima. Metode. Eksperiment je vršen na šest pasa kojima je sa desne strane donje vilice, po podizanju mukoperiostalnog režnja, pravljen koštani defekt. U jedan defekt stavljana je humana deproteinizovana kost (HDK), a između nje i mekotkivnog dela stavljana je RHDM debljine 200 mikrona. U drugi defekt, koji je služio kao kontrola, stavljena je samo HDK, bez RHDM. Dva psa žrtvovana su dva meseca nakon hirurške intervencije, dva posle četiri meseca, a preostala dva šest meseci nakon hirurške intervencije. Nakon žrtvovanja uzimani su isečci za patohistološku analizu. Rezultati. Kod svih šest pasa kod kojih je u koštani defekt ugrađena HDK i RHDM stepen koštane regeneracije bio je daleko veći u odnosu na kontrolne defekte bez RHDM. Zaključak. Membrana, kao pokrivač koštanog defekta, podesna je i poboljšava koštanu regeneraciju. Koštani defekti prekriveni RHDM pokazali su značajno bolje koštano zarastanje, mada koštana regeneracija nije bila potpuna ni šest meseci nakon njene ugradnje.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Histopathological evaluation of bone regeneration using human resorbable demineralized membrane, Uticaj resorptivne membrane humanog porekla na regeneraciju koštanog tkiva - patohistološka studija",
volume = "67",
number = "6",
pages = "480-486",
doi = "10.2298/VSP1006480T"
}

Tatić, Z., Stamatović, N., Bubalo, M., Jančić, S., Račić, A., Miković, N., Tatić, N.,& Rakić, M.. (2010). Histopathological evaluation of bone regeneration using human resorbable demineralized membrane. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 67(6), 480-486.
https://doi.org/10.2298/VSP1006480T

Tatić Z, Stamatović N, Bubalo M, Jančić S, Račić A, Miković N, Tatić N, Rakić M. Histopathological evaluation of bone regeneration using human resorbable demineralized membrane. in Vojnosanitetski pregled. 2010;67(6):480-486.
doi:10.2298/VSP1006480T .

Tatić, Zoran, Stamatović, Novak, Bubalo, Marija, Jančić, Snežana, Račić, Alek, Miković, Nikola, Tatić, Natalija, Rakić, Mia, "Histopathological evaluation of bone regeneration using human resorbable demineralized membrane" in Vojnosanitetski pregled, 67, no. 6 (2010):480-486,
https://doi.org/10.2298/VSP1006480T . .

TY  - JOUR
AU  - Nedeljković, Nenad
AU  - Stamenković, Zorana
AU  - Tatić, Zoran
AU  - Račić, Alek
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1269
AB  - Backgraund/Aim. To assess the possibility of the eruption of the lower third molar on the basis of the measured parameters: retromolar space, mesiodistal crown width of a molar and the third molar angulation. Methods. The investigation included 104 patients both sexes (43 boys, and 61 girls), 16 to 25 years old (meanage, 18 years). It was performed using the orthopanthomographic radiographs analysis of those patients. Each radiograph was covered by tracing paper, and the contoures of the followiny anatomic details were drawn: a) the crown and root contours of third molars, upper and lower central incisors, distal molars in occlusion, anterior edge of ramus mandible, b) lines: 1. the occlusal plane, 2. the line of retromolar space, 3. the mesiodistal crown width of third molar, 4. the axial shaft of the third molar and the distal angle between occlusal plane and the axial shaft of the third molar. The values were measured with an orthodontic caliper: the diameter of retromolar space, diameter of mesiodistal width, the value of distal angle between occlusal plane and axial shaft of molar. Results. A favourable angulation of the lower third molar (more than 60°) was found in, boys (left 27.90%, right 32.55%), girls (left 39.34%, right 37.77%). A favourable relationship between the diameters of mesiodistal width of the third molar and retromolar space was found in, boys, (left 13.59%, right 16.27%), girls, (left 8.19%, right 14.75%). A favorable relationship between the diameters of mesiodistal width of the third molar and the retromolar space and the angulation was found in boys, (left 9.30%, right 11.62%), girls, (left 6.56%, right 9.83%). Conclusion. There was not any statistically significant difference found between the relation of the retromolar value, third molar mesiodistal diameter, or of the third molar angulation to the left and the right side nor of their mutual relations in comparing boys and girls. A favorable prognosis was found in 9.33% of the patients.
AB  - Uvod/Cilj. Ovo istraživanje imalo je za cilj procenu mogućnosti nicanja donjeg trećeg molara na osnovu izmerenih parametara: retromolarnog prostora, meziodistalnog promera umnjaka i inklinacije umnjaka. Metode. Istraživanjem je obuhvaćeno 104 ispitanika (43 dečaka i 61 devojčica) oba pola, starosti 16−25 godina. Istraživanje se zasnivalo na ortopantomografskoj analizi. Na svaki ortopantomografski snimak zalepljen je paus papir i ucrtavane su konture anatomskih detalja: a) konture krunice i korena umnjaka, centralnih gornjih i donjih inciziva, poslednjih molara u okluziji, prednje ivice ramusa mandibule, b) linije: okluzalna ravan, linija retromolarnog prostora, meziodistalni promer krunice umnjaka, aksijalna osovina umnjaka i spoljašnji ugao između okluzalne ravni i aksijalne osovine umnjaka. Merene su vrednosti: veličina retromolarnog prostora, meziodistalni promer umnjaka, vrednost spoljašnjeg ugla između aksijalne osovine umnjaka i okluzalne ravni. Rezultati. Istraživanjem je ustanovljena povoljna inklinacija donjih umnjaka (više od 60°) kod dečaka − levo 27,90%, desno 32,55%; kod devojčica − levo 39,34%, desno 37,77%. Povoljan odnos meziodistalnog promera i retromolarnog prostora nađen je kod dečaka − levo 13,59%, desno 16,27%; kod devojčica − levo 8,19%, desno 14,75%. Povoljan odnos meziodistalnog promera, retromolarnog prostora i inklinacije nađen je kod dečaka − levo 9,30%, desno 11,62%; kod devojčica − levo 6,56%, desno 9,83%. Zaključak. Nije utvrđena statistički značajna razlika u odnosu veličine retromolarnog prostora, veličine meziodistalnog promera, stepena inklinacije umnjaka leve i desne strane, kao i njihovih odnosa upoređivanjem dečaka i devojčica. Povoljna prognoza nicanja donjih trećih molara nađena je kod 9,33% ispitanika.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Possibilty of the lower third molar eruption: Radiographic analysis
T1  - Mogućnost erupcije donjeg trećeg molara - radiografska analiza
VL  - 63
IS  - 2
SP  - 159
EP  - 162
DO  - 10.2298/VSP0602159N
ER  - 

@article{
author = "Nedeljković, Nenad and Stamenković, Zorana and Tatić, Zoran and Račić, Alek",
year = "2006",
abstract = "Backgraund/Aim. To assess the possibility of the eruption of the lower third molar on the basis of the measured parameters: retromolar space, mesiodistal crown width of a molar and the third molar angulation. Methods. The investigation included 104 patients both sexes (43 boys, and 61 girls), 16 to 25 years old (meanage, 18 years). It was performed using the orthopanthomographic radiographs analysis of those patients. Each radiograph was covered by tracing paper, and the contoures of the followiny anatomic details were drawn: a) the crown and root contours of third molars, upper and lower central incisors, distal molars in occlusion, anterior edge of ramus mandible, b) lines: 1. the occlusal plane, 2. the line of retromolar space, 3. the mesiodistal crown width of third molar, 4. the axial shaft of the third molar and the distal angle between occlusal plane and the axial shaft of the third molar. The values were measured with an orthodontic caliper: the diameter of retromolar space, diameter of mesiodistal width, the value of distal angle between occlusal plane and axial shaft of molar. Results. A favourable angulation of the lower third molar (more than 60°) was found in, boys (left 27.90%, right 32.55%), girls (left 39.34%, right 37.77%). A favourable relationship between the diameters of mesiodistal width of the third molar and retromolar space was found in, boys, (left 13.59%, right 16.27%), girls, (left 8.19%, right 14.75%). A favorable relationship between the diameters of mesiodistal width of the third molar and the retromolar space and the angulation was found in boys, (left 9.30%, right 11.62%), girls, (left 6.56%, right 9.83%). Conclusion. There was not any statistically significant difference found between the relation of the retromolar value, third molar mesiodistal diameter, or of the third molar angulation to the left and the right side nor of their mutual relations in comparing boys and girls. A favorable prognosis was found in 9.33% of the patients., Uvod/Cilj. Ovo istraživanje imalo je za cilj procenu mogućnosti nicanja donjeg trećeg molara na osnovu izmerenih parametara: retromolarnog prostora, meziodistalnog promera umnjaka i inklinacije umnjaka. Metode. Istraživanjem je obuhvaćeno 104 ispitanika (43 dečaka i 61 devojčica) oba pola, starosti 16−25 godina. Istraživanje se zasnivalo na ortopantomografskoj analizi. Na svaki ortopantomografski snimak zalepljen je paus papir i ucrtavane su konture anatomskih detalja: a) konture krunice i korena umnjaka, centralnih gornjih i donjih inciziva, poslednjih molara u okluziji, prednje ivice ramusa mandibule, b) linije: okluzalna ravan, linija retromolarnog prostora, meziodistalni promer krunice umnjaka, aksijalna osovina umnjaka i spoljašnji ugao između okluzalne ravni i aksijalne osovine umnjaka. Merene su vrednosti: veličina retromolarnog prostora, meziodistalni promer umnjaka, vrednost spoljašnjeg ugla između aksijalne osovine umnjaka i okluzalne ravni. Rezultati. Istraživanjem je ustanovljena povoljna inklinacija donjih umnjaka (više od 60°) kod dečaka − levo 27,90%, desno 32,55%; kod devojčica − levo 39,34%, desno 37,77%. Povoljan odnos meziodistalnog promera i retromolarnog prostora nađen je kod dečaka − levo 13,59%, desno 16,27%; kod devojčica − levo 8,19%, desno 14,75%. Povoljan odnos meziodistalnog promera, retromolarnog prostora i inklinacije nađen je kod dečaka − levo 9,30%, desno 11,62%; kod devojčica − levo 6,56%, desno 9,83%. Zaključak. Nije utvrđena statistički značajna razlika u odnosu veličine retromolarnog prostora, veličine meziodistalnog promera, stepena inklinacije umnjaka leve i desne strane, kao i njihovih odnosa upoređivanjem dečaka i devojčica. Povoljna prognoza nicanja donjih trećih molara nađena je kod 9,33% ispitanika.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Possibilty of the lower third molar eruption: Radiographic analysis, Mogućnost erupcije donjeg trećeg molara - radiografska analiza",
volume = "63",
number = "2",
pages = "159-162",
doi = "10.2298/VSP0602159N"
}

Nedeljković, N., Stamenković, Z., Tatić, Z.,& Račić, A.. (2006). Possibilty of the lower third molar eruption: Radiographic analysis. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 63(2), 159-162.
https://doi.org/10.2298/VSP0602159N

Nedeljković N, Stamenković Z, Tatić Z, Račić A. Possibilty of the lower third molar eruption: Radiographic analysis. in Vojnosanitetski pregled. 2006;63(2):159-162.
doi:10.2298/VSP0602159N .

Nedeljković, Nenad, Stamenković, Zorana, Tatić, Zoran, Račić, Alek, "Possibilty of the lower third molar eruption: Radiographic analysis" in Vojnosanitetski pregled, 63, no. 2 (2006):159-162,
https://doi.org/10.2298/VSP0602159N . .