TY  - ADVS
AU  - Milić, Marija
AU  - Toljić, Boško
PY  - 2021
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2558
AB  - Dondersov i Hamburgeov model služe za demonstraciju uloge dijafragme, odnosno međurebarnih mišića u disanju. Ovaj video zapis sadrži postupak rada na modelima i animacije kojima se opisuju fizički principi važni za njihovo razumevanje.
T1  - Dondersov i Hamburgeov model
UR  - https://hdl.handle.net/21.15107/rcub_smile_2558
ER  - 

@misc{
author = "Milić, Marija and Toljić, Boško",
year = "2021",
abstract = "Dondersov i Hamburgeov model služe za demonstraciju uloge dijafragme, odnosno međurebarnih mišića u disanju. Ovaj video zapis sadrži postupak rada na modelima i animacije kojima se opisuju fizički principi važni za njihovo razumevanje.",
title = "Dondersov i Hamburgeov model",
url = "https://hdl.handle.net/21.15107/rcub_smile_2558"
}

Milić, M.,& Toljić, B.. (2021). Dondersov i Hamburgeov model. .
https://hdl.handle.net/21.15107/rcub_smile_2558

Milić M, Toljić B. Dondersov i Hamburgeov model. 2021;.
https://hdl.handle.net/21.15107/rcub_smile_2558 .

Milić, Marija, Toljić, Boško, "Dondersov i Hamburgeov model" (2021),
https://hdl.handle.net/21.15107/rcub_smile_2558 .

TY  - ADVS
AU  - Milić, Marija
AU  - Toljić, Boško
PY  - 2021
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2553
AB  - Video prikazuje postupak određivanja kiselosti želudačnog soka metodom neutralizacije pomoću rastvora natrijum-hidroksida. Metod omogućava određivanje kiselosti koja potiče od slobodne, vezane i ukupne hlorovodonične kiseline, kao i kiselosti koje su poreklom od drugih kiselih materija.
T1  - Određivanje kiselosti želudačnog soka
UR  - https://hdl.handle.net/21.15107/rcub_smile_2553
ER  - 

@misc{
author = "Milić, Marija and Toljić, Boško",
year = "2021",
abstract = "Video prikazuje postupak određivanja kiselosti želudačnog soka metodom neutralizacije pomoću rastvora natrijum-hidroksida. Metod omogućava određivanje kiselosti koja potiče od slobodne, vezane i ukupne hlorovodonične kiseline, kao i kiselosti koje su poreklom od drugih kiselih materija.",
title = "Određivanje kiselosti želudačnog soka",
url = "https://hdl.handle.net/21.15107/rcub_smile_2553"
}

Milić, M.,& Toljić, B.. (2021). Određivanje kiselosti želudačnog soka. .
https://hdl.handle.net/21.15107/rcub_smile_2553

Milić M, Toljić B. Određivanje kiselosti želudačnog soka. 2021;.
https://hdl.handle.net/21.15107/rcub_smile_2553 .

Milić, Marija, Toljić, Boško, "Određivanje kiselosti želudačnog soka" (2021),
https://hdl.handle.net/21.15107/rcub_smile_2553 .

TY  - JOUR
AU  - Jurišić, Tamara
AU  - Milić, Marija
AU  - Todorović, Vladimir S.
AU  - Živković, Marko
AU  - Jurišić, Milan
AU  - Milić-Lemić, Aleksandra
AU  - Tihaček-Šojić, Ljiljana
AU  - Brković, Božidar
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2497
AB  - Background/Aim. Alveolar ridge dimensional alterations following tooth extraction in the anterior maxilla often result in an inadequate bone volume for a correct implant placement. In order to obtain optimal bone volume various bone graft substitutes have become commercially available and widely used for socket grafting. The aim of this study was to examine and compare long-term clinical outcomes of dental implant therapy in the maxillary esthetic zone, after socket grafting with beta-tricalcium phosphate (TCP) combined with collagen type I, either with or without barrier membrane and flap surgery, after a 12-month follow-up. Methods. Twenty healthy patients were allocated to either C group (beta-TCP and type I collagen without mucoperiosteal flap coverage) or C+M group (beta-TCP and type I collagen barrier membrane with mucoperiosteal flap coverage). Following clinical parameters were assessed: implant stability (evaluated by a resonance frequency analysis - RFA), periimplant soft tissue stability (sulcus bleeding index - SBI, Mombelli sulcus bleeding index - MBI, periimplant sulcus depth, keratinized gingiva width, gingival level) and marginal bone level at the retroalveolar radiograms. Results. Within C+M group, RFA values significantly increased 12 weeks after implant installation compared to primary RFA values. Comparison between investigated groups showed a significantly reduced keratinized gingiva width in the C+M group compared to the C group after 3, 6, 9 and 12 months. Comparison between groups revealed significantly lower gingival level values in the C+M group at 9th and 12th month when compared to the C group. Conclusion. Implant treatment in the anterior maxilla could be effective when using a 9 months alveolar ridge preservation healing with combined treatment with beta-tricalcium phosphate and type I collagen, with regard to the peri-implant soft and hard tissue stability.
AB  - Uvod/Cilj. Posle ekstrakcije zuba, dimenzionalne promene alveolarnog grebena u estetskoj regiji gornje vilice za posledicu često imaju nedovoljnu količinu kosti za ugradnju zubnih implanata. U vezi sa tim, primenjuju se različiti koštani zamenici sa ciljem očuvanja dimenzija alveolarnog grebena posle ekstrakcije zuba. Cilj rada bio je da se, posle prezervacije alveolarnog grebena beta-trikalcijum fosfatom (TCP) sa kolagenom tip 1, sa barijernom membranom i mukoperiostalnim režnjem i bez nje, ispitaju i uporede klinički ishodi zarastanja posle ugradnje zubnih implanata u estetskoj regiji gornje vilice, tokom jednogodišnjeg perioda praćenja. Metode. Dvadeset zdravih bolesnika podeljeno je u dve grupe: C (beta TCP/kolagen tip 1 bez barijerne membrane i mukoperiostalnog režnja) i C+M (beta TCP/kolagen tip 1 sa barijernom membranom i mukoperiostalnim režnjem). Praćeni su uobičajeni klinički parametri ishoda terapije: implantna stabilnost (analiza rezonantne frekvence), stanje mekih tkiva (indeks krvarenja, plak indeks, širina pripojne mukoze, recesija gingive) i nivo periimplantnog koštanog tkiva na retroalveolarnom radiogramu. Rezultati. U C+M grupi, implantna stabilnost posle 12 nedelja bila je značajno veća u odnosu na primarnu stabilnost. U C+M grupi, širina keratinizovane gingive bila je značajno manja posle 3, 6, 9 i 12 meseci u odnosu na C grupu. Recesija gingive bila je značajno veća u C+M grupi u odnosu na C grupu posle 9 i 12 meseci. Zaključak. Razmatrajući stabilnost mekog i tvrdog periimplantnog tkiva, terapija zubnim implantima može biti uspešna prilikom ugradnje u estetskoj regiji gornje vilice.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Peri-implant soft and hard tissue condition after alveolar ridge preservation with beta-tricalcium phosphate/type I collagen in the maxillary esthetic zone: A 1-year follow-up study
T1  - Stanje tvrdog i mekog periimplantnog tkiva u estetskoj regiji gornje vilice posle prezervacije alveolarnog grebena beta-trikalcijum fosfatom sa kolagenom tip I - studija sa jednogodišnjim periodom praćenja
VL  - 77
IS  - 1
SP  - 22
EP  - 28
DO  - 10.2298/VSP180128047J
ER  - 

@article{
author = "Jurišić, Tamara and Milić, Marija and Todorović, Vladimir S. and Živković, Marko and Jurišić, Milan and Milić-Lemić, Aleksandra and Tihaček-Šojić, Ljiljana and Brković, Božidar",
year = "2020",
abstract = "Background/Aim. Alveolar ridge dimensional alterations following tooth extraction in the anterior maxilla often result in an inadequate bone volume for a correct implant placement. In order to obtain optimal bone volume various bone graft substitutes have become commercially available and widely used for socket grafting. The aim of this study was to examine and compare long-term clinical outcomes of dental implant therapy in the maxillary esthetic zone, after socket grafting with beta-tricalcium phosphate (TCP) combined with collagen type I, either with or without barrier membrane and flap surgery, after a 12-month follow-up. Methods. Twenty healthy patients were allocated to either C group (beta-TCP and type I collagen without mucoperiosteal flap coverage) or C+M group (beta-TCP and type I collagen barrier membrane with mucoperiosteal flap coverage). Following clinical parameters were assessed: implant stability (evaluated by a resonance frequency analysis - RFA), periimplant soft tissue stability (sulcus bleeding index - SBI, Mombelli sulcus bleeding index - MBI, periimplant sulcus depth, keratinized gingiva width, gingival level) and marginal bone level at the retroalveolar radiograms. Results. Within C+M group, RFA values significantly increased 12 weeks after implant installation compared to primary RFA values. Comparison between investigated groups showed a significantly reduced keratinized gingiva width in the C+M group compared to the C group after 3, 6, 9 and 12 months. Comparison between groups revealed significantly lower gingival level values in the C+M group at 9th and 12th month when compared to the C group. Conclusion. Implant treatment in the anterior maxilla could be effective when using a 9 months alveolar ridge preservation healing with combined treatment with beta-tricalcium phosphate and type I collagen, with regard to the peri-implant soft and hard tissue stability., Uvod/Cilj. Posle ekstrakcije zuba, dimenzionalne promene alveolarnog grebena u estetskoj regiji gornje vilice za posledicu često imaju nedovoljnu količinu kosti za ugradnju zubnih implanata. U vezi sa tim, primenjuju se različiti koštani zamenici sa ciljem očuvanja dimenzija alveolarnog grebena posle ekstrakcije zuba. Cilj rada bio je da se, posle prezervacije alveolarnog grebena beta-trikalcijum fosfatom (TCP) sa kolagenom tip 1, sa barijernom membranom i mukoperiostalnim režnjem i bez nje, ispitaju i uporede klinički ishodi zarastanja posle ugradnje zubnih implanata u estetskoj regiji gornje vilice, tokom jednogodišnjeg perioda praćenja. Metode. Dvadeset zdravih bolesnika podeljeno je u dve grupe: C (beta TCP/kolagen tip 1 bez barijerne membrane i mukoperiostalnog režnja) i C+M (beta TCP/kolagen tip 1 sa barijernom membranom i mukoperiostalnim režnjem). Praćeni su uobičajeni klinički parametri ishoda terapije: implantna stabilnost (analiza rezonantne frekvence), stanje mekih tkiva (indeks krvarenja, plak indeks, širina pripojne mukoze, recesija gingive) i nivo periimplantnog koštanog tkiva na retroalveolarnom radiogramu. Rezultati. U C+M grupi, implantna stabilnost posle 12 nedelja bila je značajno veća u odnosu na primarnu stabilnost. U C+M grupi, širina keratinizovane gingive bila je značajno manja posle 3, 6, 9 i 12 meseci u odnosu na C grupu. Recesija gingive bila je značajno veća u C+M grupi u odnosu na C grupu posle 9 i 12 meseci. Zaključak. Razmatrajući stabilnost mekog i tvrdog periimplantnog tkiva, terapija zubnim implantima može biti uspešna prilikom ugradnje u estetskoj regiji gornje vilice.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Peri-implant soft and hard tissue condition after alveolar ridge preservation with beta-tricalcium phosphate/type I collagen in the maxillary esthetic zone: A 1-year follow-up study, Stanje tvrdog i mekog periimplantnog tkiva u estetskoj regiji gornje vilice posle prezervacije alveolarnog grebena beta-trikalcijum fosfatom sa kolagenom tip I - studija sa jednogodišnjim periodom praćenja",
volume = "77",
number = "1",
pages = "22-28",
doi = "10.2298/VSP180128047J"
}

Jurišić, T., Milić, M., Todorović, V. S., Živković, M., Jurišić, M., Milić-Lemić, A., Tihaček-Šojić, L.,& Brković, B.. (2020). Peri-implant soft and hard tissue condition after alveolar ridge preservation with beta-tricalcium phosphate/type I collagen in the maxillary esthetic zone: A 1-year follow-up study. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 77(1), 22-28.
https://doi.org/10.2298/VSP180128047J

Jurišić T, Milić M, Todorović VS, Živković M, Jurišić M, Milić-Lemić A, Tihaček-Šojić L, Brković B. Peri-implant soft and hard tissue condition after alveolar ridge preservation with beta-tricalcium phosphate/type I collagen in the maxillary esthetic zone: A 1-year follow-up study. in Vojnosanitetski pregled. 2020;77(1):22-28.
doi:10.2298/VSP180128047J .

Jurišić, Tamara, Milić, Marija, Todorović, Vladimir S., Živković, Marko, Jurišić, Milan, Milić-Lemić, Aleksandra, Tihaček-Šojić, Ljiljana, Brković, Božidar, "Peri-implant soft and hard tissue condition after alveolar ridge preservation with beta-tricalcium phosphate/type I collagen in the maxillary esthetic zone: A 1-year follow-up study" in Vojnosanitetski pregled, 77, no. 1 (2020):22-28,
https://doi.org/10.2298/VSP180128047J . .

TY  - JOUR
AU  - Vučetić, Milan
AU  - Roganović, Jelena
AU  - Freilich, M.
AU  - Shafer, D.
AU  - Milić, Marija
AU  - Đukić, Ljiljana
AU  - Petrović, Nina
AU  - Marković, Evgenija
AU  - Marković, Aleksa
AU  - Brković, Božidar
PY  - 2020
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2481
AB  - Objective: To evaluate an association between bone levels of inflammation/oxidative stress mediators and postoperative discomfort after third molar conventional or piezosurgery. Material and methods: Twenty-six subjects with bilaterally impacted mandibular third molars, who underwent either piezo or conventional surgery, were included in a split-mouth design study. MicroRNA-21 (miR-21) expression, interleukin-1 beta (IL-1β), and vascular endothelial growth factor (VEGF) proteins, as well as superoxide dismutase (SOD) activity in alveolar bone, were evaluated. Pain intensity, the first pain appearance, analgesic first use and total dose taken, trismus, and swelling were clinically recorded. Results: MiR-21 expression was higher while VEGF protein was lower in piezosurgery vs. conventional groups. The differences in IL-1β protein and SOD activity were not significant between groups. The pain intensity on the first day was significantly decreased in piezosurgery group. The first pain appearance and the first analgesic taken were reported sooner in conventional vs. piezosurgical group. Significantly pronounced trismus on the third day following conventional surgery was found. In conventional group, significantly increased trismus was observed on the third compared to the first postoperative day. MiR-21 showed significant correlation with the first pain appearance. Conclusion: Delayed onset of less pronounced postoperative pain after piezosurgical vs. conventional extraction of impacted lower third molar was significantly associated with expression of bone miR-21. Clinical relevance: Alveolar bone miR-21 may reflect surgical stress and is associated with third molar postoperative pain onset.
PB  - Springer
T2  - Clinical Oral Investigations
T1  - Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort
DO  - 10.1007/s00784-020-03366-6
ER  - 

@article{
author = "Vučetić, Milan and Roganović, Jelena and Freilich, M. and Shafer, D. and Milić, Marija and Đukić, Ljiljana and Petrović, Nina and Marković, Evgenija and Marković, Aleksa and Brković, Božidar",
year = "2020",
abstract = "Objective: To evaluate an association between bone levels of inflammation/oxidative stress mediators and postoperative discomfort after third molar conventional or piezosurgery. Material and methods: Twenty-six subjects with bilaterally impacted mandibular third molars, who underwent either piezo or conventional surgery, were included in a split-mouth design study. MicroRNA-21 (miR-21) expression, interleukin-1 beta (IL-1β), and vascular endothelial growth factor (VEGF) proteins, as well as superoxide dismutase (SOD) activity in alveolar bone, were evaluated. Pain intensity, the first pain appearance, analgesic first use and total dose taken, trismus, and swelling were clinically recorded. Results: MiR-21 expression was higher while VEGF protein was lower in piezosurgery vs. conventional groups. The differences in IL-1β protein and SOD activity were not significant between groups. The pain intensity on the first day was significantly decreased in piezosurgery group. The first pain appearance and the first analgesic taken were reported sooner in conventional vs. piezosurgical group. Significantly pronounced trismus on the third day following conventional surgery was found. In conventional group, significantly increased trismus was observed on the third compared to the first postoperative day. MiR-21 showed significant correlation with the first pain appearance. Conclusion: Delayed onset of less pronounced postoperative pain after piezosurgical vs. conventional extraction of impacted lower third molar was significantly associated with expression of bone miR-21. Clinical relevance: Alveolar bone miR-21 may reflect surgical stress and is associated with third molar postoperative pain onset.",
publisher = "Springer",
journal = "Clinical Oral Investigations",
title = "Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort",
doi = "10.1007/s00784-020-03366-6"
}

Vučetić, M., Roganović, J., Freilich, M., Shafer, D., Milić, M., Đukić, L., Petrović, N., Marković, E., Marković, A.,& Brković, B.. (2020). Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort. in Clinical Oral Investigations
Springer..
https://doi.org/10.1007/s00784-020-03366-6

Vučetić M, Roganović J, Freilich M, Shafer D, Milić M, Đukić L, Petrović N, Marković E, Marković A, Brković B. Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort. in Clinical Oral Investigations. 2020;.
doi:10.1007/s00784-020-03366-6 .

Vučetić, Milan, Roganović, Jelena, Freilich, M., Shafer, D., Milić, Marija, Đukić, Ljiljana, Petrović, Nina, Marković, Evgenija, Marković, Aleksa, Brković, Božidar, "Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort" in Clinical Oral Investigations (2020),
https://doi.org/10.1007/s00784-020-03366-6 . .

TY  - JOUR
AU  - Ćetković, Dejan
AU  - Milić, Marija
AU  - Biočanin, Vladimir
AU  - Brajić, Ivana
AU  - Ćalasan, Dejan
AU  - Radović, Katarina
AU  - Živković, Rade
AU  - Brković, Božidar
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2448
AB  - Bacground/Aim. The efficient dental anesthesia, which is related to the clinically adequate depth, duration and the width of anesthetic field, is an important prerequisite for successful dental treatment. The aim of this study was to investigate and compare the pulpal anesthesia and cardiovascular parameters after the anterior middle superior alveolar (AMSA) nerve block with 4% articaine with epinephrine administered by conventional cartridge-syringe and computer-controlled local anesthetic delivery system (CCLADS). Methods. This controlled double-blind cross-over randomized clinical study included 38 healthy volunteers. Efficacy of pulpal anesthesia after the AMSA nerve block was evaluated by measuring a success rate, onset and duration of pulpal anesthesia, using an electrical pulp tester. The parameters of cardiovascular function (systolic and diastolic blood pressure, heart rate) were monitored noninvasively. Results. Successful pulpal anesthesia of all tested teeth was obtained in 57.9% participants with CCLADS and in 44.7% participants with conventional syringe. The onset time was not significantly different between two investigated groups. The pulpal anesthesia duration was not significantly different neither within nor between investigated groups. The systolic and diastolic blood pressures were significantly decreased in both investigated groups, in comparison with the baseline values. Heart rate significantly decreased within CCLADS from 10th to 30th minute when compared to baseline. Conclusion. The efficacy of pulpal anesthesia and safety of cardiovascular profile of 0.6 mL of articaine with epinephrine (1:100.000) delivered with CCLADS were improved in comparison to the conventional syringe delivery. Significant changes of cardiovascular function were not observed.
AB  - Uvod/Cilj. Efikasna zubna anestezija u pogledu klinički adekvatne dubine, trajanja i širine anestetičkog polja je važan preduslov za uspešno zubno lečenje. Cilj rada bio je ispitivanje i upoređivanje parametra anestezije zubne pulpe i kardiovaskularnih parametra posle gornje prednje i srednje alveolarne (AMSA) sprovodne anestezije postignute 4% artikainom sa epinefrinom, primenom standardne karpulbrizgalice i kompjuterski kontrolisanog sistema za primenu anestetičkog rastvora (CCLADS). Metode. U ovom randomizovanom, prospektivnom, kontrolisanom, dvostruko slepom ukrštenom kliničkom istraživanju učestvovalo je 38 ispitanika. Kvalitet anestezije zubne pulpe posle AMSA anestezije praćen je na osnovu uspešnosti, latentnog perioda i trajanja anestezije zubne pulpe, primenom električnog pulp-testera. Parametri kardiovaskularne funkcije (sistolni i dijastolni krvni pritisak, srčana frekvencija) praćeni su neinvazivno, primenom aparata za monitoring. Rezultati. Uspešna anestezija zubne pulpe svih ispitivanih zuba bila je prisutna kod 57,9% ispitanika posle kod CCLADS i kod 44,7% ispitanika posle primene standardne karpul-brizgalice. Latentni period i trajanje anestezije zubne pulpe nisu se značajno razlikovali između ispitivanih grupa. Sistolni i dijastolni pritisak bili su značajno sniženi u praćenim vremenskim intervalima u odnosu na početne vrednosti. Srčana frekvencija je bila značajno snižena kod CCLADS grupe od 10 do 30 minuta u odnosu na početne vrednosti. Zaključak. Kontrolisanom kompjuterizovanom primenom (CCLADS) 0,6 mL 4% artikaina sa epinefrinom (1:100,000) za AMSA sprovodnu anesteziju, postignut je bolji kvalitet anestezije zubne pulpe u odnosu na primenu artikaina sa epinefrinom standardnom karpul brizgalicom. Nisu uočene bitne promene funkcija kardiovaskularnog sistema.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study
T1  - Efikasnost i sigurnost 4% artikaina sa epinefrinom za gornji prednji i srednji alveolarni nervni blok primenom kompjuterski kontrolisanog sistema i standardnog pristupa za primenu anestetičkog rastvora - prospektivna, randomizovana, kontrolisana, dvosturko slepa, ukrštena klinička studija
VL  - 76
IS  - 10
SP  - 1045
EP  - 1053
DO  - 10.2298/VSP170511013C
ER  - 

@article{
author = "Ćetković, Dejan and Milić, Marija and Biočanin, Vladimir and Brajić, Ivana and Ćalasan, Dejan and Radović, Katarina and Živković, Rade and Brković, Božidar",
year = "2019",
abstract = "Bacground/Aim. The efficient dental anesthesia, which is related to the clinically adequate depth, duration and the width of anesthetic field, is an important prerequisite for successful dental treatment. The aim of this study was to investigate and compare the pulpal anesthesia and cardiovascular parameters after the anterior middle superior alveolar (AMSA) nerve block with 4% articaine with epinephrine administered by conventional cartridge-syringe and computer-controlled local anesthetic delivery system (CCLADS). Methods. This controlled double-blind cross-over randomized clinical study included 38 healthy volunteers. Efficacy of pulpal anesthesia after the AMSA nerve block was evaluated by measuring a success rate, onset and duration of pulpal anesthesia, using an electrical pulp tester. The parameters of cardiovascular function (systolic and diastolic blood pressure, heart rate) were monitored noninvasively. Results. Successful pulpal anesthesia of all tested teeth was obtained in 57.9% participants with CCLADS and in 44.7% participants with conventional syringe. The onset time was not significantly different between two investigated groups. The pulpal anesthesia duration was not significantly different neither within nor between investigated groups. The systolic and diastolic blood pressures were significantly decreased in both investigated groups, in comparison with the baseline values. Heart rate significantly decreased within CCLADS from 10th to 30th minute when compared to baseline. Conclusion. The efficacy of pulpal anesthesia and safety of cardiovascular profile of 0.6 mL of articaine with epinephrine (1:100.000) delivered with CCLADS were improved in comparison to the conventional syringe delivery. Significant changes of cardiovascular function were not observed., Uvod/Cilj. Efikasna zubna anestezija u pogledu klinički adekvatne dubine, trajanja i širine anestetičkog polja je važan preduslov za uspešno zubno lečenje. Cilj rada bio je ispitivanje i upoređivanje parametra anestezije zubne pulpe i kardiovaskularnih parametra posle gornje prednje i srednje alveolarne (AMSA) sprovodne anestezije postignute 4% artikainom sa epinefrinom, primenom standardne karpulbrizgalice i kompjuterski kontrolisanog sistema za primenu anestetičkog rastvora (CCLADS). Metode. U ovom randomizovanom, prospektivnom, kontrolisanom, dvostruko slepom ukrštenom kliničkom istraživanju učestvovalo je 38 ispitanika. Kvalitet anestezije zubne pulpe posle AMSA anestezije praćen je na osnovu uspešnosti, latentnog perioda i trajanja anestezije zubne pulpe, primenom električnog pulp-testera. Parametri kardiovaskularne funkcije (sistolni i dijastolni krvni pritisak, srčana frekvencija) praćeni su neinvazivno, primenom aparata za monitoring. Rezultati. Uspešna anestezija zubne pulpe svih ispitivanih zuba bila je prisutna kod 57,9% ispitanika posle kod CCLADS i kod 44,7% ispitanika posle primene standardne karpul-brizgalice. Latentni period i trajanje anestezije zubne pulpe nisu se značajno razlikovali između ispitivanih grupa. Sistolni i dijastolni pritisak bili su značajno sniženi u praćenim vremenskim intervalima u odnosu na početne vrednosti. Srčana frekvencija je bila značajno snižena kod CCLADS grupe od 10 do 30 minuta u odnosu na početne vrednosti. Zaključak. Kontrolisanom kompjuterizovanom primenom (CCLADS) 0,6 mL 4% artikaina sa epinefrinom (1:100,000) za AMSA sprovodnu anesteziju, postignut je bolji kvalitet anestezije zubne pulpe u odnosu na primenu artikaina sa epinefrinom standardnom karpul brizgalicom. Nisu uočene bitne promene funkcija kardiovaskularnog sistema.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study, Efikasnost i sigurnost 4% artikaina sa epinefrinom za gornji prednji i srednji alveolarni nervni blok primenom kompjuterski kontrolisanog sistema i standardnog pristupa za primenu anestetičkog rastvora - prospektivna, randomizovana, kontrolisana, dvosturko slepa, ukrštena klinička studija",
volume = "76",
number = "10",
pages = "1045-1053",
doi = "10.2298/VSP170511013C"
}

Ćetković, D., Milić, M., Biočanin, V., Brajić, I., Ćalasan, D., Radović, K., Živković, R.,& Brković, B.. (2019). Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(10), 1045-1053.
https://doi.org/10.2298/VSP170511013C

Ćetković D, Milić M, Biočanin V, Brajić I, Ćalasan D, Radović K, Živković R, Brković B. Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study. in Vojnosanitetski pregled. 2019;76(10):1045-1053.
doi:10.2298/VSP170511013C .

Ćetković, Dejan, Milić, Marija, Biočanin, Vladimir, Brajić, Ivana, Ćalasan, Dejan, Radović, Katarina, Živković, Rade, Brković, Božidar, "Efficacy and safety of 4% articaine with epinephrine for the anterior middle superior alveolar nerve block comparing to the computer controlled and conventional anesthetic delivery: Prospective, randomized, cross-over clinical study" in Vojnosanitetski pregled, 76, no. 10 (2019):1045-1053,
https://doi.org/10.2298/VSP170511013C . .

TY  - JOUR
AU  - Todorović, Vladimir S.
AU  - Milić, Marija
AU  - Vasović, Miroslav
AU  - Nikolić, Živorad
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2349
AB  - Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease with a variety of oral manifestations (dry mouth, reduced salivary flow, painful mucosal lesions and restricted mouth opening, impaired oral hygiene maintenance), as well as possible far-reaching systemic implications. In the context of SLE, oral rehabilitation with dental implants might be the most appropriate solution. However, a lack of available literature, as well as the absence of treatment protocols, often leads to unsatisfactory management of these patients. The aim of this paper was to describe oral rehabilitation of a patient with SLE using dental implants and fixed dentures in both jaws. Case outline A 66-year-old female patient, who had suffered from SLE for over 30 years, was referred for oral rehabilitation as her chief complaints related to the existing mobile partial dentures in the jaws and poor chewing ability. Proposed oral rehabilitation with fixed dentures supported by six dental implants in the maxilla and four dental implants in the mandible, as well as prosthetic restoration of the mandibular teeth, was accepted by the patient. During the follow-up period of three years, no biological complications were observed related to the performed treatment. Conclusion Dental implants might be the most suitable treatment modality for oral rehabilitation of patients suffering from SLE.
AB  - Uvod Sistemski eritematozni lupus (SLE) jeste hronično autoimuno oboljenje sa različitim sistemskim i oralnim manifestacijama (kserostomija, bolne sluzokožne lezije i bolno otvaranje usta, otežano sprovođenje adekvatne oralne higijene), kao i mogućim sistemskim komplikacijama. Oralna rehabilitacija bolesnika sa SLE fiksnim zubnim nadoknadama nošenim zubnim implantatima može predstavljati najprikladniji vid terapije. Međutim, usled ograničenih informacija iz dostupne literature, kao i nedostatka terapijskih protokola, i danas se u praksi ovi bolesnici neadekvatno protetski zbrinjavaju mobilnim nadoknadama. Cilj ovog rada je bio da prikaže bolesnicu obolelu od SLE koja je zbrinuta fiksnim zubnim nadoknadama nošenim zubnim implantatima u obe vilice. Prikaz bolesnika Žena, 66 godina stara, sa evolucijom SLE od 30 godina, upućena je na oralnu rehabilitaciju zbog problema sa mobilnim parcijalnim protezama obe vilice i nemogućnosti žvakanja. Prihvatila je preporučenu oralnu rehabilitaciju sa šest dentalnih implantata u gornjoj i četiri u donjoj vilici. Tokom perioda praćenja od tri godine nisu uočene biološke komplikacije. Zaključak Terapija zubnim implantatima se može smatrati najboljim terapijskim modalitetom u oralnoj rehabilitaciji bolesnika obolelih od SLE.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Oral rehabilitation of a patient with systemic lupus erythematosus using implant-supported fixed dentures: A case report with review of important considerations
T1  - Oralna rehabilitacija bolesnika sa sistemskim eritematoznim lupusom fiksnim zubnim nadoknadama na zubnim implantatima - prikaz slučaja i pregled značajnih saznanja
VL  - 146
IS  - 9-10
SP  - 567
EP  - 571
DO  - 10.2298/SARH170912209T
ER  - 

@article{
author = "Todorović, Vladimir S. and Milić, Marija and Vasović, Miroslav and Nikolić, Živorad",
year = "2018",
abstract = "Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease with a variety of oral manifestations (dry mouth, reduced salivary flow, painful mucosal lesions and restricted mouth opening, impaired oral hygiene maintenance), as well as possible far-reaching systemic implications. In the context of SLE, oral rehabilitation with dental implants might be the most appropriate solution. However, a lack of available literature, as well as the absence of treatment protocols, often leads to unsatisfactory management of these patients. The aim of this paper was to describe oral rehabilitation of a patient with SLE using dental implants and fixed dentures in both jaws. Case outline A 66-year-old female patient, who had suffered from SLE for over 30 years, was referred for oral rehabilitation as her chief complaints related to the existing mobile partial dentures in the jaws and poor chewing ability. Proposed oral rehabilitation with fixed dentures supported by six dental implants in the maxilla and four dental implants in the mandible, as well as prosthetic restoration of the mandibular teeth, was accepted by the patient. During the follow-up period of three years, no biological complications were observed related to the performed treatment. Conclusion Dental implants might be the most suitable treatment modality for oral rehabilitation of patients suffering from SLE., Uvod Sistemski eritematozni lupus (SLE) jeste hronično autoimuno oboljenje sa različitim sistemskim i oralnim manifestacijama (kserostomija, bolne sluzokožne lezije i bolno otvaranje usta, otežano sprovođenje adekvatne oralne higijene), kao i mogućim sistemskim komplikacijama. Oralna rehabilitacija bolesnika sa SLE fiksnim zubnim nadoknadama nošenim zubnim implantatima može predstavljati najprikladniji vid terapije. Međutim, usled ograničenih informacija iz dostupne literature, kao i nedostatka terapijskih protokola, i danas se u praksi ovi bolesnici neadekvatno protetski zbrinjavaju mobilnim nadoknadama. Cilj ovog rada je bio da prikaže bolesnicu obolelu od SLE koja je zbrinuta fiksnim zubnim nadoknadama nošenim zubnim implantatima u obe vilice. Prikaz bolesnika Žena, 66 godina stara, sa evolucijom SLE od 30 godina, upućena je na oralnu rehabilitaciju zbog problema sa mobilnim parcijalnim protezama obe vilice i nemogućnosti žvakanja. Prihvatila je preporučenu oralnu rehabilitaciju sa šest dentalnih implantata u gornjoj i četiri u donjoj vilici. Tokom perioda praćenja od tri godine nisu uočene biološke komplikacije. Zaključak Terapija zubnim implantatima se može smatrati najboljim terapijskim modalitetom u oralnoj rehabilitaciji bolesnika obolelih od SLE.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Oral rehabilitation of a patient with systemic lupus erythematosus using implant-supported fixed dentures: A case report with review of important considerations, Oralna rehabilitacija bolesnika sa sistemskim eritematoznim lupusom fiksnim zubnim nadoknadama na zubnim implantatima - prikaz slučaja i pregled značajnih saznanja",
volume = "146",
number = "9-10",
pages = "567-571",
doi = "10.2298/SARH170912209T"
}

Todorović, V. S., Milić, M., Vasović, M.,& Nikolić, Ž.. (2018). Oral rehabilitation of a patient with systemic lupus erythematosus using implant-supported fixed dentures: A case report with review of important considerations. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 146(9-10), 567-571.
https://doi.org/10.2298/SARH170912209T

Todorović VS, Milić M, Vasović M, Nikolić Ž. Oral rehabilitation of a patient with systemic lupus erythematosus using implant-supported fixed dentures: A case report with review of important considerations. in Srpski arhiv za celokupno lekarstvo. 2018;146(9-10):567-571.
doi:10.2298/SARH170912209T .

Todorović, Vladimir S., Milić, Marija, Vasović, Miroslav, Nikolić, Živorad, "Oral rehabilitation of a patient with systemic lupus erythematosus using implant-supported fixed dentures: A case report with review of important considerations" in Srpski arhiv za celokupno lekarstvo, 146, no. 9-10 (2018):567-571,
https://doi.org/10.2298/SARH170912209T . .

TY  - JOUR
AU  - Biočanin, Vladimir
AU  - Antonijević, Đorđe
AU  - Poštić, Srđan
AU  - Ilić, Dragan
AU  - Vuković, Zorica
AU  - Milić, Marija
AU  - Fan, Yifang
AU  - Li, Zhiyu
AU  - Brković, Božidar
AU  - Durić, Marija
PY  - 2018
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2289
AB  - Introduction: The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Methods: Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro computed tomographic (mu CT) imaging. Extracted upper human incisors were retrofilled, and mu CT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). Results: No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ([10 +/- 30] x 10(-3) mm(3)). Conclusions: Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface.
PB  - Elsevier Science Inc, New York
T2  - Journal of Endodontics
T1  - Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin
VL  - 44
IS  - 5
SP  - 816
EP  - 821
DO  - 10.1016/j.joen.2017.09.022
ER  - 

@article{
author = "Biočanin, Vladimir and Antonijević, Đorđe and Poštić, Srđan and Ilić, Dragan and Vuković, Zorica and Milić, Marija and Fan, Yifang and Li, Zhiyu and Brković, Božidar and Durić, Marija",
year = "2018",
abstract = "Introduction: The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggregate (MTA+; Cerkamed Company, Stalowa Wola, Poland), and glass ionomer cement (Fuji IX; GC Corporation, Tokyo, Japan). Methods: Materials' wettability was calculated concerning the contact angles of the cements measured using a glycerol drop. Cements' porosity was determined using mercury intrusion porosimetry and micro computed tomographic (mu CT) imaging. Extracted upper human incisors were retrofilled, and mu CT analysis was applied to calculate the volume of the gap between the retrograde filling material and root canal dentin. Experiments were performed before and after soaking the materials in simulated body fluid (SBF). Results: No statistically significant differences were found among the contact angles of the studied materials after being soaked in SBF. The material with the lowest nanoporosity (Fuji IX: 2.99% and 4.17% before and after SBF, respectively) showed the highest values of microporosity (4.2% and 3.1% before and after SBF, respectively). Biodentine had the lowest value of microporosity (1.2% and 0.8% before and after SBF, respectively) and the lowest value of microgap to the root canal wall ([10 +/- 30] x 10(-3) mm(3)). Conclusions: Biodentine and MTA possess certain advantages over Fuji IX for hermetic obturation of retrograde root canals. Biodentine shows a tendency toward the lowest marginal gap at the cement-to-dentin interface.",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Endodontics",
title = "Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin",
volume = "44",
number = "5",
pages = "816-821",
doi = "10.1016/j.joen.2017.09.022"
}

Biočanin, V., Antonijević, Đ., Poštić, S., Ilić, D., Vuković, Z., Milić, M., Fan, Y., Li, Z., Brković, B.,& Durić, M.. (2018). Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin. in Journal of Endodontics
Elsevier Science Inc, New York., 44(5), 816-821.
https://doi.org/10.1016/j.joen.2017.09.022

Biočanin V, Antonijević Đ, Poštić S, Ilić D, Vuković Z, Milić M, Fan Y, Li Z, Brković B, Durić M. Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin. in Journal of Endodontics. 2018;44(5):816-821.
doi:10.1016/j.joen.2017.09.022 .

Biočanin, Vladimir, Antonijević, Đorđe, Poštić, Srđan, Ilić, Dragan, Vuković, Zorica, Milić, Marija, Fan, Yifang, Li, Zhiyu, Brković, Božidar, Durić, Marija, "Marginal Gaps between 2 Calcium Silicate and Glass lonomer Cements and Apical Root Dentin" in Journal of Endodontics, 44, no. 5 (2018):816-821,
https://doi.org/10.1016/j.joen.2017.09.022 . .

TY  - THES
AU  - Milić, Marija
PY  - 2017
UR  - https://plus.sr.cobiss.net/opac7/bib/1024317838
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/729
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Agresivne parodontopatije
UR  - https://hdl.handle.net/21.15107/rcub_smile_729
ER  - 

@misc{
author = "Milić, Marija",
year = "2017",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Agresivne parodontopatije",
url = "https://hdl.handle.net/21.15107/rcub_smile_729"
}

Milić, M.. (2017). Agresivne parodontopatije. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_729

Milić M. Agresivne parodontopatije. 2017;.
https://hdl.handle.net/21.15107/rcub_smile_729 .

Milić, Marija, "Agresivne parodontopatije" (2017),
https://hdl.handle.net/21.15107/rcub_smile_729 .

TY  - JOUR
AU  - Brković, Božidar
AU  - Andrić, Miroslav
AU  - Ćalasan, Dejan
AU  - Milić, Marija
AU  - Stepić, Jelena
AU  - Vučetić, Milan
AU  - Brajković, Denis
AU  - Todorović, Ljubomir
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2241
AB  - The purpose of this study was to investigate postoperative analgesic effect of ropivacaine administered as main or supplemental injection for the inferior alveolar nerve block (IANB) in patients undergoing lower third molar surgery. The double-blind randomized study comprised 72 healthy patients. All patients received two blocks, the IANB for surgical procedure + IANB after surgery for postoperative pain control, and were divided into three groups: (1) 2 % lidocaine/epinephrine + 1 % ropivacaine, (2) 2 % lidocaine/epinephrine + saline, and (3) 1 % ropivacaine + saline. The occurrence of postoperative pain, pain intensity and analgesic requirements were recorded. Data were statistically analyzed using chi-square, Fisher, and Kruskal-Wallis tests and analysis of variance (ANOVA) with Bonferroni and Tukey correction. Ropivacaine was more successful than lidocaine/epinephrine in obtaining duration of postoperative analgesia, reduction of pain, and analgesic requirements whether ropivacaine was used for surgical block or administered as a supplemental injection after surgery. Ropivacaine (1 %, 2 ml) resulted in effective postoperative analgesia after lower third molar surgery. Since pain control related to third molar surgery requires the effective surgical anesthesia and postoperative analgesia, the use of 1 % ropivacaine could be clinically relevant in a selection of appropriate pain control regimen for both surgical procedure and early postsurgical treatment.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study
VL  - 21
IS  - 3
SP  - 779
EP  - 785
DO  - 10.1007/s00784-016-1831-2
ER  - 

@article{
author = "Brković, Božidar and Andrić, Miroslav and Ćalasan, Dejan and Milić, Marija and Stepić, Jelena and Vučetić, Milan and Brajković, Denis and Todorović, Ljubomir",
year = "2017",
abstract = "The purpose of this study was to investigate postoperative analgesic effect of ropivacaine administered as main or supplemental injection for the inferior alveolar nerve block (IANB) in patients undergoing lower third molar surgery. The double-blind randomized study comprised 72 healthy patients. All patients received two blocks, the IANB for surgical procedure + IANB after surgery for postoperative pain control, and were divided into three groups: (1) 2 % lidocaine/epinephrine + 1 % ropivacaine, (2) 2 % lidocaine/epinephrine + saline, and (3) 1 % ropivacaine + saline. The occurrence of postoperative pain, pain intensity and analgesic requirements were recorded. Data were statistically analyzed using chi-square, Fisher, and Kruskal-Wallis tests and analysis of variance (ANOVA) with Bonferroni and Tukey correction. Ropivacaine was more successful than lidocaine/epinephrine in obtaining duration of postoperative analgesia, reduction of pain, and analgesic requirements whether ropivacaine was used for surgical block or administered as a supplemental injection after surgery. Ropivacaine (1 %, 2 ml) resulted in effective postoperative analgesia after lower third molar surgery. Since pain control related to third molar surgery requires the effective surgical anesthesia and postoperative analgesia, the use of 1 % ropivacaine could be clinically relevant in a selection of appropriate pain control regimen for both surgical procedure and early postsurgical treatment.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study",
volume = "21",
number = "3",
pages = "779-785",
doi = "10.1007/s00784-016-1831-2"
}

Brković, B., Andrić, M., Ćalasan, D., Milić, M., Stepić, J., Vučetić, M., Brajković, D.,& Todorović, L.. (2017). Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 21(3), 779-785.
https://doi.org/10.1007/s00784-016-1831-2

Brković B, Andrić M, Ćalasan D, Milić M, Stepić J, Vučetić M, Brajković D, Todorović L. Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study. in Clinical Oral Investigations. 2017;21(3):779-785.
doi:10.1007/s00784-016-1831-2 .

Brković, Božidar, Andrić, Miroslav, Ćalasan, Dejan, Milić, Marija, Stepić, Jelena, Vučetić, Milan, Brajković, Denis, Todorović, Ljubomir, "Efficacy and safety of 1% ropivacaine for postoperative analgesia after lower third molar surgery: a prospective, randomized, double-blinded clinical study" in Clinical Oral Investigations, 21, no. 3 (2017):779-785,
https://doi.org/10.1007/s00784-016-1831-2 . .

TY  - THES
AU  - Milić, Marija
PY  - 2016
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=4677
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:14868/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=48769807
UR  - http://nardus.mpn.gov.rs/123456789/7721
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/994
AB  - Introduction Patients with diabetes mellitus (DM) type 2 are at increased risk for performance of regional anaesthesia, due to macrovascular and microvascular complications of DM, including changes in small blood vessels of peripheral nerves (diabetic neuropathy). Results of experimental studies show that local anesthetics, even in clinically applicable concentrations, cause more pronounced damage to the nerves in the presence of DM, with clinically observable changes in parameters of regional anaesthesia. Neuropathic and microangiopathic changes caused by DM are also observed in the oral cavity tissues of DM patients. To date, there are no available data on efficacy and safety of intraoral local anaestehsia in patients with DM. Aims The aims of this doctoral dissertation were to test and compare efficacy and safety of intraoral local anaesthesia obtained with 2% lidocaine with clonidine (15 mcg / ml) (LC) and 2% lidocaine with epinephrine (1:80 000) (LE) in healthy and DM type 2 participants, by assessing the parameters of pulpal and soft tissues anaesthesia, pulpal blood flow, parameters of postoperative analgesia, presence of local side effects, as well as parameters of cardiovascular functions in the settings with and without oral surgical procedure. Material and method This prospective, double blind, randomized, controlled clinical study was performed in two parts. One part of the study included 36 healthy (ASA I) i 36 DM tip 2 participants (ASA II i ASA III), who received tested anaesthetic solutions (LC i LE) for maxillary infiltration anestehesia, in cross over-manner with washout period of 14 days, in the setting without oral surgical procedure. Tested parameters were: pulpal blood flow, parameters of pulpal anaesthesia and cardiovascular functions. Following part of the study involved 106 healthy (ASA I) i 127 DM tip 2 patients (ASA II i ASA III), divided into 8 groups according to health status, anaesthesia technique (infiltration, block) and tested anesthetic solution (LC, LE). In this study population the tested parameters were: soft tissue anaesthesia, postoperative analgesia, local side effects and cardiovascular parameters after infiltration and block application of either LC or LE, for extraction of single-rooted teeth in upper and lower jaw. Pulpal blood flow of maxillary central incisors was measured by laser Dopler flowmetry prior to, as well as 5, 10, 15, 30, 45 and 60 minutes after maxillary infiltration anaesthesia...
AB  - Uvod Pacijenti sa dijabetes melitusom (DM), zbog pratećih makrovaskularnih i mikrovaskularnih komplikacija osnovnog oboljenja, koje zahvataju i periferne nerve (dijabetična neuropatija), predstavljaju pacijente rizika za primenu regionalne anestezije. Pokazano je u eksperimentalnim uslovima da lokalni anestetici, u klinički primenljivim koncentracijama, izazivaju veća oštećenja na nervima izmenjenim dijabetičnom neuropatijom, što se u kliničkim uslovima manifestuje promenjenim parametrima regionalne anestezije. Promene koje DM izaziva na krvnim sudovima i nervima su zapažene i u tkivima i organima orofacijalne regije. Za sada nema podataka o parametrima i bezbednosti primene intraoralne lokalne anestezije u uslovima DM. Ciljevi Ovo istraživanje je imalo za ciljeve da ispita i uporedi efikasnost i bezbednost intraoralne lokalne anestezije postignute primenom 2% lidokaina sa klonidinom (15 mcg / ml) (LC) i 2% lidokaina sa epinefrinom (1:80 000) (LE) kod zdravih i ispitanika sa DM tip 2, praćenjem kliničkih parametara anestezije zubne pulpe i mekih tkiva, protoka krvi kroz zubnu pulpu, parametara postoperativne analgezije, učestalosti lokalnih neželjenih efekata, kao i parametara kardiovaskularne funkcije u uslovima sa i bez oralnohirurške intervencije. Materijal i metod Ova prospektivna, dvostruko slepa, randomizovana, kontrolisana klinička studija je izvedena u dva dela. U jednom delu studije učestvovalo je 36 zdravih (ASA I) i 36 ispitanika sa DM tip 2 (ASA II i ASA III), koji su u ukrštenom dizajnu istraživanja bez oralnohirurške intervencije, u razmaku od 14 dana dobili ispitivane anestetičke rastvore (LC i LE) za maksilarnu infiltracionu anesteziju, pri čemu su ispitivani protok krvi kroz zubnu pulpu maksilarnih centralnih sekutića, kao i parametri anestezije zubne pulpe i kardiovaskularne funkcije. U drugom delu studije učestvovalo je 106 zdravih (ASA I) i 127 ispitanika sa DM tip 2 (ASA II i ASA III), koji su prema zdravstvenom statusu, tehnici anestezije (infiltraciona, sprovodna) i vrsti anestetičkog rastvora (LC, LE) podeljeni u 8 grupa...
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Efficacy and safety of lidocaine with clonidine for intraoral local anaesthesia in patients with diabetes mellitus type 2
T1  - Efikasnost i bezbednost intraoralne lokalne anestezije primenom lidokaina sa klonidinom kod pacijenata sa dijabetes melitusom tip 2
UR  - https://hdl.handle.net/21.15107/rcub_nardus_7721
ER  - 

@phdthesis{
author = "Milić, Marija",
year = "2016",
abstract = "Introduction Patients with diabetes mellitus (DM) type 2 are at increased risk for performance of regional anaesthesia, due to macrovascular and microvascular complications of DM, including changes in small blood vessels of peripheral nerves (diabetic neuropathy). Results of experimental studies show that local anesthetics, even in clinically applicable concentrations, cause more pronounced damage to the nerves in the presence of DM, with clinically observable changes in parameters of regional anaesthesia. Neuropathic and microangiopathic changes caused by DM are also observed in the oral cavity tissues of DM patients. To date, there are no available data on efficacy and safety of intraoral local anaestehsia in patients with DM. Aims The aims of this doctoral dissertation were to test and compare efficacy and safety of intraoral local anaesthesia obtained with 2% lidocaine with clonidine (15 mcg / ml) (LC) and 2% lidocaine with epinephrine (1:80 000) (LE) in healthy and DM type 2 participants, by assessing the parameters of pulpal and soft tissues anaesthesia, pulpal blood flow, parameters of postoperative analgesia, presence of local side effects, as well as parameters of cardiovascular functions in the settings with and without oral surgical procedure. Material and method This prospective, double blind, randomized, controlled clinical study was performed in two parts. One part of the study included 36 healthy (ASA I) i 36 DM tip 2 participants (ASA II i ASA III), who received tested anaesthetic solutions (LC i LE) for maxillary infiltration anestehesia, in cross over-manner with washout period of 14 days, in the setting without oral surgical procedure. Tested parameters were: pulpal blood flow, parameters of pulpal anaesthesia and cardiovascular functions. Following part of the study involved 106 healthy (ASA I) i 127 DM tip 2 patients (ASA II i ASA III), divided into 8 groups according to health status, anaesthesia technique (infiltration, block) and tested anesthetic solution (LC, LE). In this study population the tested parameters were: soft tissue anaesthesia, postoperative analgesia, local side effects and cardiovascular parameters after infiltration and block application of either LC or LE, for extraction of single-rooted teeth in upper and lower jaw. Pulpal blood flow of maxillary central incisors was measured by laser Dopler flowmetry prior to, as well as 5, 10, 15, 30, 45 and 60 minutes after maxillary infiltration anaesthesia..., Uvod Pacijenti sa dijabetes melitusom (DM), zbog pratećih makrovaskularnih i mikrovaskularnih komplikacija osnovnog oboljenja, koje zahvataju i periferne nerve (dijabetična neuropatija), predstavljaju pacijente rizika za primenu regionalne anestezije. Pokazano je u eksperimentalnim uslovima da lokalni anestetici, u klinički primenljivim koncentracijama, izazivaju veća oštećenja na nervima izmenjenim dijabetičnom neuropatijom, što se u kliničkim uslovima manifestuje promenjenim parametrima regionalne anestezije. Promene koje DM izaziva na krvnim sudovima i nervima su zapažene i u tkivima i organima orofacijalne regije. Za sada nema podataka o parametrima i bezbednosti primene intraoralne lokalne anestezije u uslovima DM. Ciljevi Ovo istraživanje je imalo za ciljeve da ispita i uporedi efikasnost i bezbednost intraoralne lokalne anestezije postignute primenom 2% lidokaina sa klonidinom (15 mcg / ml) (LC) i 2% lidokaina sa epinefrinom (1:80 000) (LE) kod zdravih i ispitanika sa DM tip 2, praćenjem kliničkih parametara anestezije zubne pulpe i mekih tkiva, protoka krvi kroz zubnu pulpu, parametara postoperativne analgezije, učestalosti lokalnih neželjenih efekata, kao i parametara kardiovaskularne funkcije u uslovima sa i bez oralnohirurške intervencije. Materijal i metod Ova prospektivna, dvostruko slepa, randomizovana, kontrolisana klinička studija je izvedena u dva dela. U jednom delu studije učestvovalo je 36 zdravih (ASA I) i 36 ispitanika sa DM tip 2 (ASA II i ASA III), koji su u ukrštenom dizajnu istraživanja bez oralnohirurške intervencije, u razmaku od 14 dana dobili ispitivane anestetičke rastvore (LC i LE) za maksilarnu infiltracionu anesteziju, pri čemu su ispitivani protok krvi kroz zubnu pulpu maksilarnih centralnih sekutića, kao i parametri anestezije zubne pulpe i kardiovaskularne funkcije. U drugom delu studije učestvovalo je 106 zdravih (ASA I) i 127 ispitanika sa DM tip 2 (ASA II i ASA III), koji su prema zdravstvenom statusu, tehnici anestezije (infiltraciona, sprovodna) i vrsti anestetičkog rastvora (LC, LE) podeljeni u 8 grupa...",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Efficacy and safety of lidocaine with clonidine for intraoral local anaesthesia in patients with diabetes mellitus type 2, Efikasnost i bezbednost intraoralne lokalne anestezije primenom lidokaina sa klonidinom kod pacijenata sa dijabetes melitusom tip 2",
url = "https://hdl.handle.net/21.15107/rcub_nardus_7721"
}

Milić, M.. (2016). Efficacy and safety of lidocaine with clonidine for intraoral local anaesthesia in patients with diabetes mellitus type 2. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_nardus_7721

Milić M. Efficacy and safety of lidocaine with clonidine for intraoral local anaesthesia in patients with diabetes mellitus type 2. 2016;.
https://hdl.handle.net/21.15107/rcub_nardus_7721 .

Milić, Marija, "Efficacy and safety of lidocaine with clonidine for intraoral local anaesthesia in patients with diabetes mellitus type 2" (2016),
https://hdl.handle.net/21.15107/rcub_nardus_7721 .

TY  - JOUR
AU  - Milić, Marija
AU  - Brković, Božidar
AU  - Kršljak, Elena
AU  - Stojić, Dragica
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2179
AB  - The pulpal anesthetic and cardiovascular parameters obtained by 2 % lidocaine with epinephrine (LE; 1:80,000) or clonidine (LC; 15 mcg/ml) were studied in diabetes mellitus (DM) type 2 and healthy volunteers (72), after maxillary infiltration anesthesia. Onset and duration of pulpal anesthesia were measured by electric pulp tester; vasoconstrictive effect of used local anesthetic mixtures by laser Doppler flowmetry (LDF) through pulpal blood flow (PBF); systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were registered by electrocardiogram monitoring. Onset of pulpal anesthesia was shorter for LC than for LE in healthy, while it was not different in diabetic participants; duration of pulpal anesthesia was significantly longer in type 2 diabetic participants, regardless of used anesthetic mixture. Significant reduction of PBF with LE was observed during 45 min in healthy and 60 min in diabetic participants, while with LC such reduction was observed during 45 min in both groups. LE caused a significant increase of SBP in the 5th and 15th minutes in diabetic versus healthy participants, while LC decreased SBP from the 10th to 60th minutes in healthy versus diabetic participants. DM type 2 influences duration of maxillary infiltration anesthesia obtained with LE and LC, and systolic blood pressure during LE anesthesia. The obtained results provide elements for future protocols concerning intraoral local anesthesia in DM type 2 patients.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers
VL  - 20
IS  - 6
SP  - 1283
EP  - 1293
DO  - 10.1007/s00784-015-1610-5
ER  - 

@article{
author = "Milić, Marija and Brković, Božidar and Kršljak, Elena and Stojić, Dragica",
year = "2016",
abstract = "The pulpal anesthetic and cardiovascular parameters obtained by 2 % lidocaine with epinephrine (LE; 1:80,000) or clonidine (LC; 15 mcg/ml) were studied in diabetes mellitus (DM) type 2 and healthy volunteers (72), after maxillary infiltration anesthesia. Onset and duration of pulpal anesthesia were measured by electric pulp tester; vasoconstrictive effect of used local anesthetic mixtures by laser Doppler flowmetry (LDF) through pulpal blood flow (PBF); systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were registered by electrocardiogram monitoring. Onset of pulpal anesthesia was shorter for LC than for LE in healthy, while it was not different in diabetic participants; duration of pulpal anesthesia was significantly longer in type 2 diabetic participants, regardless of used anesthetic mixture. Significant reduction of PBF with LE was observed during 45 min in healthy and 60 min in diabetic participants, while with LC such reduction was observed during 45 min in both groups. LE caused a significant increase of SBP in the 5th and 15th minutes in diabetic versus healthy participants, while LC decreased SBP from the 10th to 60th minutes in healthy versus diabetic participants. DM type 2 influences duration of maxillary infiltration anesthesia obtained with LE and LC, and systolic blood pressure during LE anesthesia. The obtained results provide elements for future protocols concerning intraoral local anesthesia in DM type 2 patients.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers",
volume = "20",
number = "6",
pages = "1283-1293",
doi = "10.1007/s00784-015-1610-5"
}

Milić, M., Brković, B., Kršljak, E.,& Stojić, D.. (2016). Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 20(6), 1283-1293.
https://doi.org/10.1007/s00784-015-1610-5

Milić M, Brković B, Kršljak E, Stojić D. Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers. in Clinical Oral Investigations. 2016;20(6):1283-1293.
doi:10.1007/s00784-015-1610-5 .

Milić, Marija, Brković, Božidar, Kršljak, Elena, Stojić, Dragica, "Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers" in Clinical Oral Investigations, 20, no. 6 (2016):1283-1293,
https://doi.org/10.1007/s00784-015-1610-5 . .

TY  - JOUR
AU  - Milić, Marija
AU  - Brković, Božidar
AU  - Kršljak, Elena
AU  - Stojić, Dragica
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2149
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers (vol 20, pg 1283, 2016)
VL  - 20
IS  - 6
SP  - 1295
EP  - 1296
DO  - 10.1007/s00784-015-1628-8
ER  - 

@article{
author = "Milić, Marija and Brković, Božidar and Kršljak, Elena and Stojić, Dragica",
year = "2016",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers (vol 20, pg 1283, 2016)",
volume = "20",
number = "6",
pages = "1295-1296",
doi = "10.1007/s00784-015-1628-8"
}

Milić, M., Brković, B., Kršljak, E.,& Stojić, D.. (2016). Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers (vol 20, pg 1283, 2016). in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 20(6), 1295-1296.
https://doi.org/10.1007/s00784-015-1628-8

Milić M, Brković B, Kršljak E, Stojić D. Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers (vol 20, pg 1283, 2016). in Clinical Oral Investigations. 2016;20(6):1295-1296.
doi:10.1007/s00784-015-1628-8 .

Milić, Marija, Brković, Božidar, Kršljak, Elena, Stojić, Dragica, "Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers (vol 20, pg 1283, 2016)" in Clinical Oral Investigations, 20, no. 6 (2016):1295-1296,
https://doi.org/10.1007/s00784-015-1628-8 . .

TY  - JOUR
AU  - Biočanin, Vladimir
AU  - Milić, Marija
AU  - Vučetić, Milan
AU  - Baćević, Miljana
AU  - Vasović, Dina
AU  - Živadinović, Milka
AU  - Ćetković, Dejan
AU  - Ćalasan, Dejan
AU  - Brković, Božidar
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2073
AB  - Introduction. The material used for root-end filling has to be biocompatible with adjacent periapical tissue and to stimulate its regenerative processes. Tricalcium silicate cement (TSC), as a new dental material, shows good sealing properties with dentin, high compression strengths and better marginal adaptation than commonly used root-end filling materials. Although optimal postoperative healing of periapical tissues is mainly influenced by characteristics of end-root material used, it could sometimes be affected by the influence of systemic diseases, such as diabetes mellitus (DM). Case report. We presented apical healing of the upper central incisor, retrofilled with TSC, in a diabetic patient (type 2 DM) with peripheral neuropathy. Standard root-end resection of upper central incisor was accompanied by retropreparation using ultrasonic retrotips to the depth of 3 mm and retrofilling with TSC. Postoperatively, the surgical wound healed uneventfully. However, the patient reported undefined dull pain in the operated area that could possibly be attributed to undiagnosed intraoral diabetic peripheral neuropathy, what was evaluated clinically. Conclusion. Although TSC presents a suitable material for apical root-end filling in the treatment of chronic periradicular lesions a possible presence of systemic diseases, like type 2 DM, has to be considered in the treatment outcome estimation.
AB  - Uvod. Materijal koji se koristi za retrogradnu opturaciju kanala korena trebalo bi da bude biokompatibilan sa okolnim periapeksnim tkivom i da stimuliše procese njegove regeneracije. Trikalcijum silikatni cement (TSC), kao novi dentalni materijal, pokazuje dobro zaptivanje, visoku kompresivnu snagu i bolju ivičnu adaptaciju u odnosu na standardno korišćene materijale za retroopturaciju. Iako postoperativno zarastanje periapikalnog tkiva najviše zavisi od karakteristika materijala za retroopturaciju, ponekad na uspeh zarastanja može uticati i prisustvo neke sistemske bolesti kao što je dijabetes melitus (DM). Prikaz bolesnika. Prikazali smo apikalno zarastanje u predelu gornjeg centralnog sekutića, nakon retroopturacije sa TSC, kod bolesnika sa DM tipa 2 i prisutnom perifernom neuropatijom. Standardna resekcija korena gornjeg centralnog sekutića bila je urađena retropreparacijom ultrazvučnim nastavcima do dubine od 3 mm i retrogradnom opturacijom sa TSC. Zarastanje postoperativne regije bilo je u fiziološkim granicama. Bolesnik se, međutim, žalio na nedefinisan, tup bol u predelu operisane regije koji je verovatno bio povezan sa nedijagnostikovanom intraoralnom dijabetičnom perifernom neuropatijom, što je potvrđeno kliničkim nalazom. Zaključak. Iako TSC predstavlja pogodan materijal za retrogradnu opturaciju kanala korena zuba u lečenju hroničnih periradikularnih lezija, u proceni ishoda lečenja treba imati u vidu i moguće prisustvo perifernih manfestacija sistemskih bolesti kao što je DM tipa 2.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report
T1  - Punjenje kanala korena cementom na bazi trikalcijum-silikata kod bolesnika sa dijabetesom melitusom
VL  - 73
IS  - 12
SP  - 1173
EP  - 1177
DO  - 10.2298/VSP150606137B
ER  - 

@article{
author = "Biočanin, Vladimir and Milić, Marija and Vučetić, Milan and Baćević, Miljana and Vasović, Dina and Živadinović, Milka and Ćetković, Dejan and Ćalasan, Dejan and Brković, Božidar",
year = "2016",
abstract = "Introduction. The material used for root-end filling has to be biocompatible with adjacent periapical tissue and to stimulate its regenerative processes. Tricalcium silicate cement (TSC), as a new dental material, shows good sealing properties with dentin, high compression strengths and better marginal adaptation than commonly used root-end filling materials. Although optimal postoperative healing of periapical tissues is mainly influenced by characteristics of end-root material used, it could sometimes be affected by the influence of systemic diseases, such as diabetes mellitus (DM). Case report. We presented apical healing of the upper central incisor, retrofilled with TSC, in a diabetic patient (type 2 DM) with peripheral neuropathy. Standard root-end resection of upper central incisor was accompanied by retropreparation using ultrasonic retrotips to the depth of 3 mm and retrofilling with TSC. Postoperatively, the surgical wound healed uneventfully. However, the patient reported undefined dull pain in the operated area that could possibly be attributed to undiagnosed intraoral diabetic peripheral neuropathy, what was evaluated clinically. Conclusion. Although TSC presents a suitable material for apical root-end filling in the treatment of chronic periradicular lesions a possible presence of systemic diseases, like type 2 DM, has to be considered in the treatment outcome estimation., Uvod. Materijal koji se koristi za retrogradnu opturaciju kanala korena trebalo bi da bude biokompatibilan sa okolnim periapeksnim tkivom i da stimuliše procese njegove regeneracije. Trikalcijum silikatni cement (TSC), kao novi dentalni materijal, pokazuje dobro zaptivanje, visoku kompresivnu snagu i bolju ivičnu adaptaciju u odnosu na standardno korišćene materijale za retroopturaciju. Iako postoperativno zarastanje periapikalnog tkiva najviše zavisi od karakteristika materijala za retroopturaciju, ponekad na uspeh zarastanja može uticati i prisustvo neke sistemske bolesti kao što je dijabetes melitus (DM). Prikaz bolesnika. Prikazali smo apikalno zarastanje u predelu gornjeg centralnog sekutića, nakon retroopturacije sa TSC, kod bolesnika sa DM tipa 2 i prisutnom perifernom neuropatijom. Standardna resekcija korena gornjeg centralnog sekutića bila je urađena retropreparacijom ultrazvučnim nastavcima do dubine od 3 mm i retrogradnom opturacijom sa TSC. Zarastanje postoperativne regije bilo je u fiziološkim granicama. Bolesnik se, međutim, žalio na nedefinisan, tup bol u predelu operisane regije koji je verovatno bio povezan sa nedijagnostikovanom intraoralnom dijabetičnom perifernom neuropatijom, što je potvrđeno kliničkim nalazom. Zaključak. Iako TSC predstavlja pogodan materijal za retrogradnu opturaciju kanala korena zuba u lečenju hroničnih periradikularnih lezija, u proceni ishoda lečenja treba imati u vidu i moguće prisustvo perifernih manfestacija sistemskih bolesti kao što je DM tipa 2.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report, Punjenje kanala korena cementom na bazi trikalcijum-silikata kod bolesnika sa dijabetesom melitusom",
volume = "73",
number = "12",
pages = "1173-1177",
doi = "10.2298/VSP150606137B"
}

Biočanin, V., Milić, M., Vučetić, M., Baćević, M., Vasović, D., Živadinović, M., Ćetković, D., Ćalasan, D.,& Brković, B.. (2016). Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 73(12), 1173-1177.
https://doi.org/10.2298/VSP150606137B

Biočanin V, Milić M, Vučetić M, Baćević M, Vasović D, Živadinović M, Ćetković D, Ćalasan D, Brković B. Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report. in Vojnosanitetski pregled. 2016;73(12):1173-1177.
doi:10.2298/VSP150606137B .

Biočanin, Vladimir, Milić, Marija, Vučetić, Milan, Baćević, Miljana, Vasović, Dina, Živadinović, Milka, Ćetković, Dejan, Ćalasan, Dejan, Brković, Božidar, "Apical root-end filling with tricalcium silicate-based cement in a patient with diabetes mellitus: A case report" in Vojnosanitetski pregled, 73, no. 12 (2016):1173-1177,
https://doi.org/10.2298/VSP150606137B . .

TY  - JOUR
AU  - Brajković, Denis
AU  - Biočanin, Vladimir
AU  - Milić, Marija
AU  - Vučetić, Milan
AU  - Petrović, Renata
AU  - Brković, Božidar
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2044
AB  - Background/Aim. Surgical extraction of lower third molars is followed by mild or severe postoperative pain which peaks at maximal intensity in the first 12 hours and has a significant impact on a patient's postoperative quality of life. The use of long-acting local anaesthetics is a promising strategy to improve postoperative analgesia. The aim of the present study was to investigate analgesic parameters and patient satisfaction after using 0.5% levobupivacaine (Lbup), 0.5% bupivacaine (Bup) and 2% lidocaine with epinephrine 1:80,000 (Lid + Epi) for an inferior alveolar nerve block following lower third molar surgery. Methods. A total of 102 patients (ASA I) were divided into three groups, each of which received either 3 mL of Lbup, Bup or Lid + Epi. The intensity of postoperative analgesia was measured using a verbal rating scale (VRS). The total amounts of rescue analgesics were recorded on the first and during seven postoperative days. Patients satisfaction was noted using a modified verbal scales. Results. A significantly higher level of postoperative pain was recorded in Lid + Epi group compared to Bup and Lbup groups. No significant differences were seen between Bup and Lbup, but a significant reduction in the need for rescue analgesics was seen postoperatively in both Lbup and Bup (50%) in comparison with Lid + Epi (80%) in the first 24 hours. The same significant trend in rescue analgesic consumption was recorded for seven postoperative days. Patients' overall satisfaction was significantly lower for Lid + Epi (10%) than for Lbup (56%) and Bup (52%). Conclusion. The use of a new and long-acting local anaesthetic 0.5% levobupivacaine is clinically relevant and effective for an inferior alveolar nerve block and postoperative pain control after third molar surgery. In our study Lbup and Bup controlled postoperative pain more efficiently after lower third molar surgery compared to Lid + Epi.
AB  - Uvod/Cilj. Hirurško vađenje donjih impaktiranih umnjaka praćeno je bolom umerenog do jakog intenziteta, sa maksimalnim intenzitetom tokom prvih 12 sati, koji ima značajan uticaj na kvalitet života pacijenata u postoperativnom periodu. Upotreba dugodelujućih lokalnih anestetika predstavlja obećavajuću strategiju za poboljšanje postoperativne analgezije. Cilj ove studije bio je da se ispitaju analgeticki parametri i zadovoljstvo pacijenata postignutom analgezijom u postoperativnom periodu nakon primene 0,5% levobupivakaina (Lbup), 0,5% bupivakaina (Bup) i 2% lidokaina sa epinefrinom (1: 80,000) (Lid + Epi) za sprovodnu anesteziju donjeg alveolarnog nerva prilikom hirurškog vađenja donjih umnjaka. Metode. Ukupno 102 pacijenta (ASA I) bila su podeljena u tri grupe u zavisnosti od primljenog anestetika: 3 mL Lbup, 3 mL Bup ili 3 mL Lid + Epi. Intenzitet postoperativne analgezije registrovan je primenom verbalne rangirajuće skale (VRS). Zabeležena je ukupna količina primenjenih analgetika nakon prvog i sedmog postoperativnog dana. Zadovoljstvo pacijenata ocenjivano je na osnovu modifikovanih verbalnih skala. Rezultati. Značajno jači intenzitet postoperativnog bola zabeležen je u grupi Lid + Epi, u poređenju sa grupama Lbup i Bup. Značajno smanjenje potrebe za analgeticima u postoperativnom periodu zabeleženo u grupama Lbup i Bup (50%) u poređenju sa grupom Lid + Epi (80%) nakon 24 časa. Značajno smanjenje potrebe za postoperativnim analgeticima u grupama Lbup i Bup zabeleženo je i nakon 7 dana. Potpuno zadovoljstvo pacijenata postignutom analgezijom bilo je značajno slabije u grupi Lid + Epi (10%) u poređenju sa grupama Lbup (56%) i Bup (52%). Zaključak. Upotreba novog dugodelujućeg lokalnog anestetika 0,5% levobupivakaina klinički je relevantna i efikasna za sprovodnu anesteziju donjeg alveolarnog nerva i kontrolu postoperativnog bola nakon hirurškog vađenja donjih umnjaka. U našoj studiji Lbup i Bup bili su efikasniji u kontroli postoperativnog bola nakon hirurškog vađenja donjih umnjaka u poređenju sa Lid + Epi.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine
T1  - Kvalitet analgezije nakon hirurškog vađenja donjih umnjaka - randomizovana, duplo slepa studija efikasnosti levobupivakaina, bupivakaina i lidokaina sa adrenalinom
VL  - 72
IS  - 1
SP  - 50
EP  - 56
DO  - 10.2298/VSP1501050B
ER  - 

@article{
author = "Brajković, Denis and Biočanin, Vladimir and Milić, Marija and Vučetić, Milan and Petrović, Renata and Brković, Božidar",
year = "2015",
abstract = "Background/Aim. Surgical extraction of lower third molars is followed by mild or severe postoperative pain which peaks at maximal intensity in the first 12 hours and has a significant impact on a patient's postoperative quality of life. The use of long-acting local anaesthetics is a promising strategy to improve postoperative analgesia. The aim of the present study was to investigate analgesic parameters and patient satisfaction after using 0.5% levobupivacaine (Lbup), 0.5% bupivacaine (Bup) and 2% lidocaine with epinephrine 1:80,000 (Lid + Epi) for an inferior alveolar nerve block following lower third molar surgery. Methods. A total of 102 patients (ASA I) were divided into three groups, each of which received either 3 mL of Lbup, Bup or Lid + Epi. The intensity of postoperative analgesia was measured using a verbal rating scale (VRS). The total amounts of rescue analgesics were recorded on the first and during seven postoperative days. Patients satisfaction was noted using a modified verbal scales. Results. A significantly higher level of postoperative pain was recorded in Lid + Epi group compared to Bup and Lbup groups. No significant differences were seen between Bup and Lbup, but a significant reduction in the need for rescue analgesics was seen postoperatively in both Lbup and Bup (50%) in comparison with Lid + Epi (80%) in the first 24 hours. The same significant trend in rescue analgesic consumption was recorded for seven postoperative days. Patients' overall satisfaction was significantly lower for Lid + Epi (10%) than for Lbup (56%) and Bup (52%). Conclusion. The use of a new and long-acting local anaesthetic 0.5% levobupivacaine is clinically relevant and effective for an inferior alveolar nerve block and postoperative pain control after third molar surgery. In our study Lbup and Bup controlled postoperative pain more efficiently after lower third molar surgery compared to Lid + Epi., Uvod/Cilj. Hirurško vađenje donjih impaktiranih umnjaka praćeno je bolom umerenog do jakog intenziteta, sa maksimalnim intenzitetom tokom prvih 12 sati, koji ima značajan uticaj na kvalitet života pacijenata u postoperativnom periodu. Upotreba dugodelujućih lokalnih anestetika predstavlja obećavajuću strategiju za poboljšanje postoperativne analgezije. Cilj ove studije bio je da se ispitaju analgeticki parametri i zadovoljstvo pacijenata postignutom analgezijom u postoperativnom periodu nakon primene 0,5% levobupivakaina (Lbup), 0,5% bupivakaina (Bup) i 2% lidokaina sa epinefrinom (1: 80,000) (Lid + Epi) za sprovodnu anesteziju donjeg alveolarnog nerva prilikom hirurškog vađenja donjih umnjaka. Metode. Ukupno 102 pacijenta (ASA I) bila su podeljena u tri grupe u zavisnosti od primljenog anestetika: 3 mL Lbup, 3 mL Bup ili 3 mL Lid + Epi. Intenzitet postoperativne analgezije registrovan je primenom verbalne rangirajuće skale (VRS). Zabeležena je ukupna količina primenjenih analgetika nakon prvog i sedmog postoperativnog dana. Zadovoljstvo pacijenata ocenjivano je na osnovu modifikovanih verbalnih skala. Rezultati. Značajno jači intenzitet postoperativnog bola zabeležen je u grupi Lid + Epi, u poređenju sa grupama Lbup i Bup. Značajno smanjenje potrebe za analgeticima u postoperativnom periodu zabeleženo u grupama Lbup i Bup (50%) u poređenju sa grupom Lid + Epi (80%) nakon 24 časa. Značajno smanjenje potrebe za postoperativnim analgeticima u grupama Lbup i Bup zabeleženo je i nakon 7 dana. Potpuno zadovoljstvo pacijenata postignutom analgezijom bilo je značajno slabije u grupi Lid + Epi (10%) u poređenju sa grupama Lbup (56%) i Bup (52%). Zaključak. Upotreba novog dugodelujućeg lokalnog anestetika 0,5% levobupivakaina klinički je relevantna i efikasna za sprovodnu anesteziju donjeg alveolarnog nerva i kontrolu postoperativnog bola nakon hirurškog vađenja donjih umnjaka. U našoj studiji Lbup i Bup bili su efikasniji u kontroli postoperativnog bola nakon hirurškog vađenja donjih umnjaka u poređenju sa Lid + Epi.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine, Kvalitet analgezije nakon hirurškog vađenja donjih umnjaka - randomizovana, duplo slepa studija efikasnosti levobupivakaina, bupivakaina i lidokaina sa adrenalinom",
volume = "72",
number = "1",
pages = "50-56",
doi = "10.2298/VSP1501050B"
}

Brajković, D., Biočanin, V., Milić, M., Vučetić, M., Petrović, R.,& Brković, B.. (2015). Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 72(1), 50-56.
https://doi.org/10.2298/VSP1501050B

Brajković D, Biočanin V, Milić M, Vučetić M, Petrović R, Brković B. Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine. in Vojnosanitetski pregled. 2015;72(1):50-56.
doi:10.2298/VSP1501050B .

Brajković, Denis, Biočanin, Vladimir, Milić, Marija, Vučetić, Milan, Petrović, Renata, Brković, Božidar, "Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine" in Vojnosanitetski pregled, 72, no. 1 (2015):50-56,
https://doi.org/10.2298/VSP1501050B . .

TY  - JOUR
AU  - Brajković, Denis
AU  - Brković, Božidar
AU  - Milić, Marija
AU  - Biočanin, Vladimir
AU  - Kršljak, Elena
AU  - Stojić, Dragica
PY  - 2014
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1857
AB  - The main purpose of this prospective, double-blind, randomized study was to evaluate anaesthetic parameters, postoperative analgesia and vasoactive properties of levobupivacaine and bupivacaine for lower third molar surgery. Sixty patients (ASA I) were scheduled for lower third molar surgery under inferior alveolar nerve block, lingual nerve block and buccal nerve block (mandibular nerve blocks) obtained with 3 ml of 0.5 % levobupivacaine and 3 ml of 0.5 % bupivacaine. Success rate, onset and duration of three nerve bocks were evaluated by electrical pulp testing, pinprick testing and signs of soft tissue anaesthesia (patient-reported numbness). Intensity of intraoperative anaesthesia and postoperative analgesia were measured with visual analogue scale (VAS) and numeric rating scale (NRS). The time of first postoperative pain reported and analgesic consumption were also recorded. The laser Doppler flowmetry was used for the measurement of the first premolar pulpal blood flow. There were no differences between levobupivacaine and bupivacaine regarding the success rate, onset and duration of mandibular nerve blocks as well as intensity of postoperative analgesia and analgesic consumption. Intensity of intraoperative anaesthesia and duration of postoperative analgesia were significantly higher in the levobupivacaine than in the bupivacaine group. Both anaesthetics showed similar biphasic vasoactive effect. Levobupivacaine 0.5 % achieved superiority over bupivacaine 0.5 % in the intensity of intraoperative anaesthesia and duration of postoperative analgesia for lower third molar surgery under the mandibular nerve blocks. It seems that the plain levobupivacaine (0.5 %) could be an effective alternative to plain bupivacaine (0.5 %) in those dental procedures which require profound bone and soft tissue anaesthesia.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Levobupivacaine vs. bupivacaine for third molar surgery: quality of anaesthesia, postoperative analgesia and local vascular effects
VL  - 18
IS  - 5
SP  - 1481
EP  - 1488
DO  - 10.1007/s00784-013-1114-0
ER  - 

@article{
author = "Brajković, Denis and Brković, Božidar and Milić, Marija and Biočanin, Vladimir and Kršljak, Elena and Stojić, Dragica",
year = "2014",
abstract = "The main purpose of this prospective, double-blind, randomized study was to evaluate anaesthetic parameters, postoperative analgesia and vasoactive properties of levobupivacaine and bupivacaine for lower third molar surgery. Sixty patients (ASA I) were scheduled for lower third molar surgery under inferior alveolar nerve block, lingual nerve block and buccal nerve block (mandibular nerve blocks) obtained with 3 ml of 0.5 % levobupivacaine and 3 ml of 0.5 % bupivacaine. Success rate, onset and duration of three nerve bocks were evaluated by electrical pulp testing, pinprick testing and signs of soft tissue anaesthesia (patient-reported numbness). Intensity of intraoperative anaesthesia and postoperative analgesia were measured with visual analogue scale (VAS) and numeric rating scale (NRS). The time of first postoperative pain reported and analgesic consumption were also recorded. The laser Doppler flowmetry was used for the measurement of the first premolar pulpal blood flow. There were no differences between levobupivacaine and bupivacaine regarding the success rate, onset and duration of mandibular nerve blocks as well as intensity of postoperative analgesia and analgesic consumption. Intensity of intraoperative anaesthesia and duration of postoperative analgesia were significantly higher in the levobupivacaine than in the bupivacaine group. Both anaesthetics showed similar biphasic vasoactive effect. Levobupivacaine 0.5 % achieved superiority over bupivacaine 0.5 % in the intensity of intraoperative anaesthesia and duration of postoperative analgesia for lower third molar surgery under the mandibular nerve blocks. It seems that the plain levobupivacaine (0.5 %) could be an effective alternative to plain bupivacaine (0.5 %) in those dental procedures which require profound bone and soft tissue anaesthesia.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Levobupivacaine vs. bupivacaine for third molar surgery: quality of anaesthesia, postoperative analgesia and local vascular effects",
volume = "18",
number = "5",
pages = "1481-1488",
doi = "10.1007/s00784-013-1114-0"
}

Brajković, D., Brković, B., Milić, M., Biočanin, V., Kršljak, E.,& Stojić, D.. (2014). Levobupivacaine vs. bupivacaine for third molar surgery: quality of anaesthesia, postoperative analgesia and local vascular effects. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 18(5), 1481-1488.
https://doi.org/10.1007/s00784-013-1114-0

Brajković D, Brković B, Milić M, Biočanin V, Kršljak E, Stojić D. Levobupivacaine vs. bupivacaine for third molar surgery: quality of anaesthesia, postoperative analgesia and local vascular effects. in Clinical Oral Investigations. 2014;18(5):1481-1488.
doi:10.1007/s00784-013-1114-0 .

Brajković, Denis, Brković, Božidar, Milić, Marija, Biočanin, Vladimir, Kršljak, Elena, Stojić, Dragica, "Levobupivacaine vs. bupivacaine for third molar surgery: quality of anaesthesia, postoperative analgesia and local vascular effects" in Clinical Oral Investigations, 18, no. 5 (2014):1481-1488,
https://doi.org/10.1007/s00784-013-1114-0 . .

TY  - JOUR
AU  - Biočanin, Vladimir
AU  - Milić, Marija
AU  - Brajković, Denis
AU  - Brković, Božidar
AU  - Stojić, Dragica
AU  - Todorović, Ljubomir
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1660
AB  - Objective. The aim of this study was to investigate quality and safety of supplemental intraoral anesthesia - periodontal ligament anaesthesia (PDL) and intraseptal anaesthesia (ISA) after computer-controlled articaine delivery. Method. 54 ASA I volunteers randomly divided into 2 groups participated in this study. 0.4 ml of 4% articaine with 1:100.000 epinephrine were randomly administered with computer-controlled local anaesthetic delivery system on the mesial and distal side of maxillary lateral incisor for ISA or PDL. An electric pulp tester was used to test the pulpal anaesthesia, in 2-minute cycles for 60 minutes. Anaesthesia was considered successful when 2 or more consecutive no-response at 80 readings were obtained. Soft-tissue anaesthesia was measured by pin-prick test. Results. Success rates for ISA and PDL were 77.8% and 55.6% respectively, but difference was not statistically significant (p>0.05). Duration of complete pulpal anaesthesia was significantly longer (p lt 0.05) with the ISA in comparison to the PDL. The width of anesthetizied field was significantly greater (p lt 0.05) with the ISA than with the PDL, both for attached gingiva and oral mucosa. No side effects were recorded during the study. Conclusion. The results of this study indicate that the ISA technique is successful in obtaining complete pulpal anaesthesia of upper lateral incisors and soft-tissue anaesthesia in this area.
PB  - Udruženje stomatologa Balkana
T2  - Balkan Journal of Stomatology
T1  - Efficacy of computer-controlled articaine delivery for supplemental intraoral anaesthesia
VL  - 15
IS  - 1
SP  - 11
EP  - 14
UR  - https://hdl.handle.net/21.15107/rcub_smile_1660
ER  - 

@article{
author = "Biočanin, Vladimir and Milić, Marija and Brajković, Denis and Brković, Božidar and Stojić, Dragica and Todorović, Ljubomir",
year = "2011",
abstract = "Objective. The aim of this study was to investigate quality and safety of supplemental intraoral anesthesia - periodontal ligament anaesthesia (PDL) and intraseptal anaesthesia (ISA) after computer-controlled articaine delivery. Method. 54 ASA I volunteers randomly divided into 2 groups participated in this study. 0.4 ml of 4% articaine with 1:100.000 epinephrine were randomly administered with computer-controlled local anaesthetic delivery system on the mesial and distal side of maxillary lateral incisor for ISA or PDL. An electric pulp tester was used to test the pulpal anaesthesia, in 2-minute cycles for 60 minutes. Anaesthesia was considered successful when 2 or more consecutive no-response at 80 readings were obtained. Soft-tissue anaesthesia was measured by pin-prick test. Results. Success rates for ISA and PDL were 77.8% and 55.6% respectively, but difference was not statistically significant (p>0.05). Duration of complete pulpal anaesthesia was significantly longer (p lt 0.05) with the ISA in comparison to the PDL. The width of anesthetizied field was significantly greater (p lt 0.05) with the ISA than with the PDL, both for attached gingiva and oral mucosa. No side effects were recorded during the study. Conclusion. The results of this study indicate that the ISA technique is successful in obtaining complete pulpal anaesthesia of upper lateral incisors and soft-tissue anaesthesia in this area.",
publisher = "Udruženje stomatologa Balkana",
journal = "Balkan Journal of Stomatology",
title = "Efficacy of computer-controlled articaine delivery for supplemental intraoral anaesthesia",
volume = "15",
number = "1",
pages = "11-14",
url = "https://hdl.handle.net/21.15107/rcub_smile_1660"
}

Biočanin, V., Milić, M., Brajković, D., Brković, B., Stojić, D.,& Todorović, L.. (2011). Efficacy of computer-controlled articaine delivery for supplemental intraoral anaesthesia. in Balkan Journal of Stomatology
Udruženje stomatologa Balkana., 15(1), 11-14.
https://hdl.handle.net/21.15107/rcub_smile_1660

Biočanin V, Milić M, Brajković D, Brković B, Stojić D, Todorović L. Efficacy of computer-controlled articaine delivery for supplemental intraoral anaesthesia. in Balkan Journal of Stomatology. 2011;15(1):11-14.
https://hdl.handle.net/21.15107/rcub_smile_1660 .

Biočanin, Vladimir, Milić, Marija, Brajković, Denis, Brković, Božidar, Stojić, Dragica, Todorović, Ljubomir, "Efficacy of computer-controlled articaine delivery for supplemental intraoral anaesthesia" in Balkan Journal of Stomatology, 15, no. 1 (2011):11-14,
https://hdl.handle.net/21.15107/rcub_smile_1660 .