@article{
author = "Martinović, Brankica and Ivanović, Mirjana and Milojković, Zoraida and Mladenović, Raša",
year = "2015",
abstract = "Background/Aim. Hypomineralization of molars and incisors (molar-incisor hypomineralization - MIH) is defined as enamel hypomineralization of systemic origin of one or more of the four first permanent molars, which may be associated with changes in the maxillary, and less frequently in the permanent mandibular incisors. The aim of this study was to investigate the mineral content in hypomineralized teeth as a contribution to under-standing the origin of these changes, which will be important for effective restorative approach. Methods. A total of 10 extracted first permanent molars diagnosed with MIH were used in the study as the experimental group, and intact first premolars extracted for orthodontic reasons were used as the control group. A certain surface of hypomineralized and healthy enamel and dentin was analyzed using a scanning electron microscope equipped with an energydispersive spectrometer (SEM/EDS). Results. By conducting quantitative chemical analysis of the distribution of the basic chemical elements, it was found that the concentration of calcium (Ca) and phosphorus (P) was significantly higher in healthy enamel (Ca = 28.80 wt%, and P = 15.05 wt%) compared to hypomineralized enamel (Ca = 27.60 wt% and P = 14.32 wt%). Carbon (C) concentration was statistically significantly higher in hypomineralized enamel (C = 11.70 wt%) compared to healthy enamel (C = 10.94 wt%). Hypomineralized and healthy enamel did not differ significantly regarding the ratio of calcium and phosphorus concentrations whereas the ratio of calcium and carbon concentrations was statistically significantly higher in healthy enamel compared to hypomineralized enamel. Conclusion. Concentration of the main chemical elements, primarily calcium and phosphorus, is significantly reduced in hypomineralized enamel whereas carbon concentration is increased compared to healthy enamel., Uvod/Cilj. Hipomineralizacija molara i sekutića (molar-incisor hipomineralisation - MIH) definiše se kao hipomineralizacija sistemskog porekla jednog ili više od četri prva stalna molara, koja može biti udružena sa promenama na maksilarnim, a nešto ređe na mandibularnim sekutićima. Cilj ovog rada bio je da se istraži mineralni sadržaj hipomineralizovanih zuba kao doprinos razumevanju nastanka ovih promena, što će biti od značaja za efikasniji restaurativni pristup. Metode. U istraživanju je korišćeno 10 izvađenih prvih stalnih molara sa dijagnozom MIH, kao eksperimentalna grupa, a kao kontrolna grupa zuba korišćeni su prvi intaktni premolari izvađeni iz ortodonskih razloga. Određena površina hipomineralizovane i zdrave gleđi i dentina analizirana je pomoću elektronskog mikroskopa opremljenog energetskim disperzionim spektrometrom (SEM/EDS). Rezultati. Kvantitativnom hemijskom analizom raspodele osnovnih hemijskih elemenata, utvrđeno je da je koncentracija kalcijuma (Ca) i fosfora (P) bila statistički značajno veća u zdravoj gleđi (Ca = 28,80% tež. i P = 15,05% tež) u odnosu na hipomineralzovanu gleđ (Ca = 27,60% tež. i P = 14.32% tež). Koncentracija ugljenika (C) bila je statistički značajno veća u hipomineralizovanoj gleđi (C = 11,70% tež) u odnosu na zdravu gleđ (C = 10,94% tež). Zdrava i hipomineralizovana gleđ nisu se statistički značajno razlikovale u odnosu koncentracija kalcijuma i fosfora, dok je odnos koncentracija kalcijuma i ugljenika statistički bio značajno veći u zdravoj gleđi u odnosu na hipomineralizovanu gleđ. Zaključak. Koncentracija osnovnih hemijskih elemenata, pre svega kalcijuma i fosfora, značajno je snižena u hipomineralizovanoj gleđi, a koncentracija ugljenika povišena u poređenju sa zdravom gleđi.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Analysis of the mineral composition of hypomineralized first permanent molars, Analiza mineralnog sastava hipomineralizovanih prvih stalnih molara",
volume = "72",
number = "10",
pages = "864-869",
doi = "10.2298/vsp140310071m"
}
