Nedić, Milica

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Therapeutic efficacy of connective tissue autotransplants with periosteum and platelet rich plasma in the management of gingival recession

Jovičić, Bojan; Lazić, Zoran; Nedić, Milica; Matijević, Stevo; Špadijer-Gostović, Aleksandra

(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2013)

TY  - JOUR
AU  - Jovičić, Bojan
AU  - Lazić, Zoran
AU  - Nedić, Milica
AU  - Matijević, Stevo
AU  - Špadijer-Gostović, Aleksandra
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1781
AB  - Background/Aim. Gingival recession progression in clinical practaice has influenced the development of various surgical procedures and techniques for solving esthetic imperfections and subjective difficulties coused by gingival recession. The aim of this study was to verify efficacy of surgical procedures and to compare both of surgical procedures through the keratinized tissue width. Methods. The study included 20 teeth with gingival recesion, Müller class I and II. Ten teeth with gingival recession were treated with connective tissue autotransplants with periosteum in combination with coronary guided surgical flap (CTG group). On the contralateral side 10 teeth with gingival recession were treated with the same surgical procedures but in combination with platelet-rich plasma (CTGPRP group). We measured the keratinized tissue width. For statistical significance we used the Student's t-test. Results. The study reveled a statistical significance in reducing vertical deepress of recession by both used treatments. Root deepness in CTG and CTG-PRP group was 90% and 93.5%, respectively. With both surgical techniques we achieved larger zone of keratinized gingiva but with a wide zone of keratinized tissue in CTG - the PRP group. Conclusion. The concept regeneration technique with PRP and with the stimulating influence of platele activated growth factors results in the regeneration of deep periodontal tissue as an important prerequisite for the successful treatment of gingival recession.
AB  - Uvod/Cilj. Sve veća zastupljenost gingivalnih recesija u svakodnevnoj kliničkoj praksi uslovila je zahteve za što efikasnijim rekonstruktivnim hirurškim procedurama, u cilju rešavanja estetskih nedostataka i subjektivnih tegoba usled povlačenja gingive. Cilj rada bio je da se uporedi efikasnost lečenja autotransplantatom vezivnog tkiva (ATVT) sa periostom i plazme obogaćene trombocitima (PRP) sa ATVT sa periostom, ali bez PRP, na širinu keratinizirane gingive. Metode. Studijama je bilo obuhvaćeno 20 zuba sa recesijama gingive klase I i II prema Mülleru. U toku terapije 10 recesija lečeno je ATVT sa periostom u kombinaciji sa koronarno pomerenim režnjima (ATVT grupa). Na kontralateralnoj strani, isti broj recesija lečen je ATVT uz koronarno pomeren režanj i uz primenu PRP (PRP + ATVT grupa). Od kliničkih parametara praćena je širina keratinizovane gingive kao pokazatelj pokrenutih regenerativnih procesa. U statističkoj obradi rezultata korišćen je Studentov t-test. Rezultati. Analizom kliničkih parametara ustanovljeno je statistički značajno proširenje zone keratinizirane gingive, što je od izuzetnog značaja za regeneraciju s tim što je proširenje bilo izraženije u ATVT + PRP grupi. Procentualno gledano, prekrivenost korena u ATVT grupi iznosila je 90%, a u ATVT + PRP grupi 93,5%. Zaključak. Primenom koncepta aktivne regeneracije odnosno primenom PRP i stimulativnim dejstvom aktiviranih faktora rasta iz trombocita, postiže se regeneracija dubljeg periodontalnog tkiva što je bitan preduslov za uspešno zbrinjavanje recesije gingive.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Therapeutic efficacy of connective tissue autotransplants with periosteum and platelet rich plasma in the management of gingival recession
T1  - Terapijski efekat plazme obogaćene trombocitima i autotransplantata vezivnog tkiva sa periostom u zbrinjavanju gingivalnih recesija
VL  - 70
IS  - 7
SP  - 664
EP  - 669
DO  - 10.2298/VSP1307664J
ER  - 
@article{
author = "Jovičić, Bojan and Lazić, Zoran and Nedić, Milica and Matijević, Stevo and Špadijer-Gostović, Aleksandra",
year = "2013",
abstract = "Background/Aim. Gingival recession progression in clinical practaice has influenced the development of various surgical procedures and techniques for solving esthetic imperfections and subjective difficulties coused by gingival recession. The aim of this study was to verify efficacy of surgical procedures and to compare both of surgical procedures through the keratinized tissue width. Methods. The study included 20 teeth with gingival recesion, Müller class I and II. Ten teeth with gingival recession were treated with connective tissue autotransplants with periosteum in combination with coronary guided surgical flap (CTG group). On the contralateral side 10 teeth with gingival recession were treated with the same surgical procedures but in combination with platelet-rich plasma (CTGPRP group). We measured the keratinized tissue width. For statistical significance we used the Student's t-test. Results. The study reveled a statistical significance in reducing vertical deepress of recession by both used treatments. Root deepness in CTG and CTG-PRP group was 90% and 93.5%, respectively. With both surgical techniques we achieved larger zone of keratinized gingiva but with a wide zone of keratinized tissue in CTG - the PRP group. Conclusion. The concept regeneration technique with PRP and with the stimulating influence of platele activated growth factors results in the regeneration of deep periodontal tissue as an important prerequisite for the successful treatment of gingival recession., Uvod/Cilj. Sve veća zastupljenost gingivalnih recesija u svakodnevnoj kliničkoj praksi uslovila je zahteve za što efikasnijim rekonstruktivnim hirurškim procedurama, u cilju rešavanja estetskih nedostataka i subjektivnih tegoba usled povlačenja gingive. Cilj rada bio je da se uporedi efikasnost lečenja autotransplantatom vezivnog tkiva (ATVT) sa periostom i plazme obogaćene trombocitima (PRP) sa ATVT sa periostom, ali bez PRP, na širinu keratinizirane gingive. Metode. Studijama je bilo obuhvaćeno 20 zuba sa recesijama gingive klase I i II prema Mülleru. U toku terapije 10 recesija lečeno je ATVT sa periostom u kombinaciji sa koronarno pomerenim režnjima (ATVT grupa). Na kontralateralnoj strani, isti broj recesija lečen je ATVT uz koronarno pomeren režanj i uz primenu PRP (PRP + ATVT grupa). Od kliničkih parametara praćena je širina keratinizovane gingive kao pokazatelj pokrenutih regenerativnih procesa. U statističkoj obradi rezultata korišćen je Studentov t-test. Rezultati. Analizom kliničkih parametara ustanovljeno je statistički značajno proširenje zone keratinizirane gingive, što je od izuzetnog značaja za regeneraciju s tim što je proširenje bilo izraženije u ATVT + PRP grupi. Procentualno gledano, prekrivenost korena u ATVT grupi iznosila je 90%, a u ATVT + PRP grupi 93,5%. Zaključak. Primenom koncepta aktivne regeneracije odnosno primenom PRP i stimulativnim dejstvom aktiviranih faktora rasta iz trombocita, postiže se regeneracija dubljeg periodontalnog tkiva što je bitan preduslov za uspešno zbrinjavanje recesije gingive.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Therapeutic efficacy of connective tissue autotransplants with periosteum and platelet rich plasma in the management of gingival recession, Terapijski efekat plazme obogaćene trombocitima i autotransplantata vezivnog tkiva sa periostom u zbrinjavanju gingivalnih recesija",
volume = "70",
number = "7",
pages = "664-669",
doi = "10.2298/VSP1307664J"
}
Jovičić, B., Lazić, Z., Nedić, M., Matijević, S.,& Špadijer-Gostović, A.. (2013). Therapeutic efficacy of connective tissue autotransplants with periosteum and platelet rich plasma in the management of gingival recession. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 70(7), 664-669.
https://doi.org/10.2298/VSP1307664J
Jovičić B, Lazić Z, Nedić M, Matijević S, Špadijer-Gostović A. Therapeutic efficacy of connective tissue autotransplants with periosteum and platelet rich plasma in the management of gingival recession. in Vojnosanitetski pregled. 2013;70(7):664-669.
doi:10.2298/VSP1307664J .
Jovičić, Bojan, Lazić, Zoran, Nedić, Milica, Matijević, Stevo, Špadijer-Gostović, Aleksandra, "Therapeutic efficacy of connective tissue autotransplants with periosteum and platelet rich plasma in the management of gingival recession" in Vojnosanitetski pregled, 70, no. 7 (2013):664-669,
https://doi.org/10.2298/VSP1307664J . .
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Regenerative surgical procedures in therapy of periodontal osseous defects

Zelić, Obrad; Aleksić, Zoran; Nedić, Milica; Crvenica, Đorđije

(Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad, 2003)

TY  - JOUR
AU  - Zelić, Obrad
AU  - Aleksić, Zoran
AU  - Nedić, Milica
AU  - Crvenica, Đorđije
PY  - 2003
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1192
AB  - The purpose of this study was to evaluate the effectiveness of a combination of new surgical procedures as a part of regenerative therapy of intrabony defects in humans and compare it to an open flap debridement technique (OFD). The results of this study indicate that the combination technique including bovine porous bone mineral, guided tissue regeneration and growth factor provide better clinical resolution of intrabony defects than treatment with OFD. Results achieved using this experimental technique are also clinically significant since they resulted in pocket reduction and clinical attachment improvement of severe lesions to maintainable levels by supportive periodontal therapy.
AB  - Cilj savremenih principa terapije obolelog parodoncijuma je regeneracija pripojnog aparata i kompletna rekontrukcija parodontalnih tkiva. To se pre svega odnosi na formiranje novog cementa, nove alveolarne kosti i funkcionalnog periodoncijuma na delu korena zuba koji je bio izložen patogenim efektima dentalnog plaka. Sve ove procedure pokazale su izvanredne kliničke rezultate u terapiji različitih oblika koštanih defekata parodoncijuma. To bi značilo da se u skoroj budućnosti mogu očekivati takvi materijali, koji će proces regeneracije tkiva parodoncijuma učiniti stvarnim i mogućim.
PB  - Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad
T2  - Stomatološki informator
T1  - Regenerative surgical procedures in therapy of periodontal osseous defects
T1  - Primena regenerativnih zahvata u terapiji obolelih od paradontopatija
VL  - 9
IS  - 12
SP  - 43
EP  - 50
UR  - https://hdl.handle.net/21.15107/rcub_smile_1192
ER  - 
@article{
author = "Zelić, Obrad and Aleksić, Zoran and Nedić, Milica and Crvenica, Đorđije",
year = "2003",
abstract = "The purpose of this study was to evaluate the effectiveness of a combination of new surgical procedures as a part of regenerative therapy of intrabony defects in humans and compare it to an open flap debridement technique (OFD). The results of this study indicate that the combination technique including bovine porous bone mineral, guided tissue regeneration and growth factor provide better clinical resolution of intrabony defects than treatment with OFD. Results achieved using this experimental technique are also clinically significant since they resulted in pocket reduction and clinical attachment improvement of severe lesions to maintainable levels by supportive periodontal therapy., Cilj savremenih principa terapije obolelog parodoncijuma je regeneracija pripojnog aparata i kompletna rekontrukcija parodontalnih tkiva. To se pre svega odnosi na formiranje novog cementa, nove alveolarne kosti i funkcionalnog periodoncijuma na delu korena zuba koji je bio izložen patogenim efektima dentalnog plaka. Sve ove procedure pokazale su izvanredne kliničke rezultate u terapiji različitih oblika koštanih defekata parodoncijuma. To bi značilo da se u skoroj budućnosti mogu očekivati takvi materijali, koji će proces regeneracije tkiva parodoncijuma učiniti stvarnim i mogućim.",
publisher = "Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad",
journal = "Stomatološki informator",
title = "Regenerative surgical procedures in therapy of periodontal osseous defects, Primena regenerativnih zahvata u terapiji obolelih od paradontopatija",
volume = "9",
number = "12",
pages = "43-50",
url = "https://hdl.handle.net/21.15107/rcub_smile_1192"
}
Zelić, O., Aleksić, Z., Nedić, M.,& Crvenica, Đ.. (2003). Regenerative surgical procedures in therapy of periodontal osseous defects. in Stomatološki informator
Društvo lekara Vojvodine Srpskog lekarskog društva, Novi Sad., 9(12), 43-50.
https://hdl.handle.net/21.15107/rcub_smile_1192
Zelić O, Aleksić Z, Nedić M, Crvenica Đ. Regenerative surgical procedures in therapy of periodontal osseous defects. in Stomatološki informator. 2003;9(12):43-50.
https://hdl.handle.net/21.15107/rcub_smile_1192 .
Zelić, Obrad, Aleksić, Zoran, Nedić, Milica, Crvenica, Đorđije, "Regenerative surgical procedures in therapy of periodontal osseous defects" in Stomatološki informator, 9, no. 12 (2003):43-50,
https://hdl.handle.net/21.15107/rcub_smile_1192 .

Primena transplantata periosta u terapiji infrakoštanih defekata parodoncijuma

Nedić, Milica

(Univerzitet u Beogradu, Stomatološki fakultet, 1996)

TY  - THES
AU  - Nedić, Milica
PY  - 1996
UR  - https://plus.sr.cobiss.net/opac7/bib/13436943
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/320
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Primena transplantata periosta u terapiji infrakoštanih defekata parodoncijuma
UR  - https://hdl.handle.net/21.15107/rcub_smile_320
ER  - 
@phdthesis{
author = "Nedić, Milica",
year = "1996",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Primena transplantata periosta u terapiji infrakoštanih defekata parodoncijuma",
url = "https://hdl.handle.net/21.15107/rcub_smile_320"
}
Nedić, M.. (1996). Primena transplantata periosta u terapiji infrakoštanih defekata parodoncijuma. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_320
Nedić M. Primena transplantata periosta u terapiji infrakoštanih defekata parodoncijuma. 1996;.
https://hdl.handle.net/21.15107/rcub_smile_320 .
Nedić, Milica, "Primena transplantata periosta u terapiji infrakoštanih defekata parodoncijuma" (1996),
https://hdl.handle.net/21.15107/rcub_smile_320 .

Eksperimentalna i klinička ispitivanja primene biokeramičkih materijala u lečenju obolelih od parodontopatija

Nedić, Milica

(Univerzitet u Beogradu, Stomatološki fakultet, 1993)

TY  - THES
AU  - Nedić, Milica
PY  - 1993
UR  - https://plus.sr.cobiss.net/opac7/bib/1024049550
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/296
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Eksperimentalna i klinička ispitivanja primene biokeramičkih materijala u lečenju obolelih od parodontopatija
UR  - https://hdl.handle.net/21.15107/rcub_smile_296
ER  - 
@mastersthesis{
author = "Nedić, Milica",
year = "1993",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Eksperimentalna i klinička ispitivanja primene biokeramičkih materijala u lečenju obolelih od parodontopatija",
url = "https://hdl.handle.net/21.15107/rcub_smile_296"
}
Nedić, M.. (1993). Eksperimentalna i klinička ispitivanja primene biokeramičkih materijala u lečenju obolelih od parodontopatija. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_296
Nedić M. Eksperimentalna i klinička ispitivanja primene biokeramičkih materijala u lečenju obolelih od parodontopatija. 1993;.
https://hdl.handle.net/21.15107/rcub_smile_296 .
Nedić, Milica, "Eksperimentalna i klinička ispitivanja primene biokeramičkih materijala u lečenju obolelih od parodontopatija" (1993),
https://hdl.handle.net/21.15107/rcub_smile_296 .