TY  - JOUR
AU  - Petrović, Vanja
AU  - Danilović, Vesna
AU  - Marković, Dejan
AU  - Čakić, Saša
AU  - Krstić, N.
AU  - Marković, Danica
PY  - 2009
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1479
AB  - There are very few data about the effects of endogenous growth factors in vital pulp therapy, and still they are often controversial. This study was undertaken with the aim to evaluate the effects of platelet rich plasma (PRP) in conjugation with hydroxyapatite (HAP), as pulp capping materials, on root and periodontium formation. Eight young monkeys (Cercopithecus Aethiops) with permanent dentition and incomplete root formation were involved in this study. After pulpotomy, the pulp lesion was capped with calcium hydroxide (control), HAP (experimental) or HAP in conjugation with PRP (experimental). Six moths later, the animals were sacrificed, the tissue was removed en block, and prepared for histological analysis in a routine way. The results of histological analysis revealed that the healing process, characterized by dentin bridge formation, maintained morphological and functional integrity of dental pulp and complete formation of dental root and surrounding periodontium. The inflammatory reaction was scored as mild to moderate, in almost all samples in all groups, suggesting the biocompatibility of the used materials. Materials used in this study are convenient as capping agents, contributing in maintaining the integrity of the pulp tissue and facilitating root and periodontium formation. According to histological data it could be suggested that hydroxyapatite in conjugation with endogenous growth factors, represent a superior alternative to other materials used in this study.
AB  - Podaci iz literature o primeni faktora rasta u vitalnoj terapiji pulpe su oskudni i često kontraverzni. Cilj našeg rada je bio da se ispita uticaj plazme bogate trombocitima u kombinaciji sa hidroksiapatitom, kao materijala za direktno prekrivanje pulpe, na završetak rasta korena i formiranje okolnog parodoncijuma. Istraživanje je sprovedeno na osam mladih majmuna (Cercopithecus aethiops), sa stalnom denticijom i nezavršenim rastom korena. Nakon pulpotomije, pulpna lezija je prekrivena kalcijum hidroksidom (kontolna grupa), hidroksiapatitom (eksperimentalna grupa I) ili hidroksiapatitom u kombinaciji sa plazmom bogatom trombocitima (eksperimentalna grupa II). Šest meseci kasnije životinje su žrtvovane, a uzeto tkivo pripremljeno je za histološku analizu. Rezultati histološke analize ukazali su da je zarastanje bilo karakterisano stvaranjem mineralizovanog dentinskog mostića, uz očuvanje morfološkog i funkcionalnog integriteta pulpe i završetak rasta korena i okolnog parodoncijuma u uzorcima svih ispitivanih grupa. Zapaljenska reakcija je gotovo u svim ispitivnim uzorcima bila ocenjena kao blaga ili umerena, što govori u prilog biokompatibilnosti primenjenih materijala. Na osnovu dobijenih rezultata može se reći da su svi primenjeni materijali pogodni za direktno prekrivanje pulpe, da doprinose očuvanju integriteta pulpe i ubrzavaju završetak rasta korena i formiranje apikalnog parodoncijuma, s tim što hidroksipatit u kombinaciji sa endogenim faktorima rasta predstavlja superiorniju alternativu u odnosu na druge materijale korišćene u ovoj studiji.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys
T1  - Uticaj hidroksiapatita i plazme bogate trombocitima na proces apeksogeneze kod majmuna
VL  - 59
IS  - 2-3
SP  - 277
EP  - 289
DO  - 10.2298/AVB0903277P
ER  - 

@article{
author = "Petrović, Vanja and Danilović, Vesna and Marković, Dejan and Čakić, Saša and Krstić, N. and Marković, Danica",
year = "2009",
abstract = "There are very few data about the effects of endogenous growth factors in vital pulp therapy, and still they are often controversial. This study was undertaken with the aim to evaluate the effects of platelet rich plasma (PRP) in conjugation with hydroxyapatite (HAP), as pulp capping materials, on root and periodontium formation. Eight young monkeys (Cercopithecus Aethiops) with permanent dentition and incomplete root formation were involved in this study. After pulpotomy, the pulp lesion was capped with calcium hydroxide (control), HAP (experimental) or HAP in conjugation with PRP (experimental). Six moths later, the animals were sacrificed, the tissue was removed en block, and prepared for histological analysis in a routine way. The results of histological analysis revealed that the healing process, characterized by dentin bridge formation, maintained morphological and functional integrity of dental pulp and complete formation of dental root and surrounding periodontium. The inflammatory reaction was scored as mild to moderate, in almost all samples in all groups, suggesting the biocompatibility of the used materials. Materials used in this study are convenient as capping agents, contributing in maintaining the integrity of the pulp tissue and facilitating root and periodontium formation. According to histological data it could be suggested that hydroxyapatite in conjugation with endogenous growth factors, represent a superior alternative to other materials used in this study., Podaci iz literature o primeni faktora rasta u vitalnoj terapiji pulpe su oskudni i često kontraverzni. Cilj našeg rada je bio da se ispita uticaj plazme bogate trombocitima u kombinaciji sa hidroksiapatitom, kao materijala za direktno prekrivanje pulpe, na završetak rasta korena i formiranje okolnog parodoncijuma. Istraživanje je sprovedeno na osam mladih majmuna (Cercopithecus aethiops), sa stalnom denticijom i nezavršenim rastom korena. Nakon pulpotomije, pulpna lezija je prekrivena kalcijum hidroksidom (kontolna grupa), hidroksiapatitom (eksperimentalna grupa I) ili hidroksiapatitom u kombinaciji sa plazmom bogatom trombocitima (eksperimentalna grupa II). Šest meseci kasnije životinje su žrtvovane, a uzeto tkivo pripremljeno je za histološku analizu. Rezultati histološke analize ukazali su da je zarastanje bilo karakterisano stvaranjem mineralizovanog dentinskog mostića, uz očuvanje morfološkog i funkcionalnog integriteta pulpe i završetak rasta korena i okolnog parodoncijuma u uzorcima svih ispitivanih grupa. Zapaljenska reakcija je gotovo u svim ispitivnim uzorcima bila ocenjena kao blaga ili umerena, što govori u prilog biokompatibilnosti primenjenih materijala. Na osnovu dobijenih rezultata može se reći da su svi primenjeni materijali pogodni za direktno prekrivanje pulpe, da doprinose očuvanju integriteta pulpe i ubrzavaju završetak rasta korena i formiranje apikalnog parodoncijuma, s tim što hidroksipatit u kombinaciji sa endogenim faktorima rasta predstavlja superiorniju alternativu u odnosu na druge materijale korišćene u ovoj studiji.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys, Uticaj hidroksiapatita i plazme bogate trombocitima na proces apeksogeneze kod majmuna",
volume = "59",
number = "2-3",
pages = "277-289",
doi = "10.2298/AVB0903277P"
}

Petrović, V., Danilović, V., Marković, D., Čakić, S., Krstić, N.,& Marković, D.. (2009). The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 59(2-3), 277-289.
https://doi.org/10.2298/AVB0903277P

Petrović V, Danilović V, Marković D, Čakić S, Krstić N, Marković D. The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys. in Acta veterinaria. 2009;59(2-3):277-289.
doi:10.2298/AVB0903277P .

Petrović, Vanja, Danilović, Vesna, Marković, Dejan, Čakić, Saša, Krstić, N., Marković, Danica, "The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys" in Acta veterinaria, 59, no. 2-3 (2009):277-289,
https://doi.org/10.2298/AVB0903277P . .

TY  - JOUR
AU  - Petrović, Vanja
AU  - Marković, Dejan
AU  - Čakić, Saša
AU  - Krstić, N.
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1400
AB  - Management of the affected pulp in teeth with incomplete root formation is still an issue. Calcium hydroxide and other materials have been employed for this purpose to a greater or lesser success. Bioceramic materials are in the last decades well established in a number of different medical fields. Having its constituents the same as those of the unorganic portion of bone tissue, hydroxiapatite (HAP), one of the two forms of calcium-phosphate ceramics, is already accepted in endodontic treatment of teeth with completed root formation. The aim of this study was to examine apexogenesis in teeth with immature roots, following the use of HAP on their affected pulp. Examination was performed on eight young monkeys (Cercopithecus Aethiops) with incomplete root development. The 100 μm synthetic HAP material was applied on 32 teeth divided into two groups of 16 teeth each. In one group teeth underwent pulpotomy, in the other high pulpotomy. Evaluation of root growth was recorded from radiographs (pre-treatment, 3 and 12 months following treatment) and by Demjrian's scale for dental maturity and tooth age determination. On the basis of radiographic analysis, immature teeth with affected pulp treated with HAP, both with pulpotomy and high pulpotomy, reached the same stage of root development as control teeth in 50% of cases at 3-months radiographic assessment. After 12 months all tested teeth had the same rate of root development as control teeth, except for 1 of 8 with high pulpotomy. Dentinal bridge was radiographically visible in 50% and 87.5% of pulpotomized teeth after 3 and 12 months, respectively. Neither obliteration of the root canal, presence of denticles nor the presence of deformities in the periapical region were found in any of the observed teeth.
AB  - Lečenja aficirane pulpe zuba sa nezavršenim rastom korena je još uvek predmet stručnih i naučnih rasprava, između ostalog i zbog neželjenih efekata tradicionalnih preparata na bazi kalcijum hidroksida. Biokeramički materijali se već nekoliko decenija primenjuju u različitim granama medicine, a hidroksiapatit, kao jedna od dve forme kalcijum-fosfatne keramike, ima gotovo istovetan sastav kao neorganski deo kosti, pa je već prihvaćen u endodontskom lečenju zuba sa završ enim rastom korena. Cilj ovog rada je bio da se ispita uticaj hidroksiapatita na apeksogenezu u zuba sa nezavršenim rastom korena i aficiranom pulpom. Ispitivanjem je bilo obuhvaćeno na osam mladih majmuna Cercopithecus Aethiops sa nezavršenim rastom korena zuba. Sintetički hidroksiapatit, veličine čestica od 100 μm je primenjen na trideset dva zuba, podeljenih u dve jednake grupe kod kojih je všena apulpotomija, odnosno visoka pulpotomija. Rendgenološ ka evaluacija rasta korena zuba je vršena pre terapije, kao i tri i dvanaest mesici posle primene HAP, a na osnovu Demjrianove skale za određivanje zrelosti zuba. Na osnovu rendgenološke analize posle 3 meseca je nađeno da je brzina razvoja korena kako pulpotomisanih, tako i visoko pulpotomisanih zuba kod kojih je primenjen HAP bila u 50% slučajeva ista kao kod kontrolnih zuba. Posle 12 meseci stepen razvoja korena zuba je u svih ispitivanih zuba (osim kod jednog od osam zuba sa izvršenom visokom pulpotomijom) bio isti kao u kontrolnih zuba. Dentinski most je bio vidljiv radiološkom analizom u 50% odnosno 87,5% eksperimentalnih zuba posle 3, odnosno posle 12 meseci. Ni u jednom pregledanom zubu rendgenološki nije uočena obliteracija kanala korena, kao ni dentikli ni deformiteti u periapeksnom predelu.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys
T1  - Uticaj hidroksiapatita na apeksogenezu u majmuna - klinička studija
VL  - 58
IS  - 4
SP  - 395
EP  - 409
DO  - 10.2298/AVB0804395P
ER  - 

@article{
author = "Petrović, Vanja and Marković, Dejan and Čakić, Saša and Krstić, N.",
year = "2008",
abstract = "Management of the affected pulp in teeth with incomplete root formation is still an issue. Calcium hydroxide and other materials have been employed for this purpose to a greater or lesser success. Bioceramic materials are in the last decades well established in a number of different medical fields. Having its constituents the same as those of the unorganic portion of bone tissue, hydroxiapatite (HAP), one of the two forms of calcium-phosphate ceramics, is already accepted in endodontic treatment of teeth with completed root formation. The aim of this study was to examine apexogenesis in teeth with immature roots, following the use of HAP on their affected pulp. Examination was performed on eight young monkeys (Cercopithecus Aethiops) with incomplete root development. The 100 μm synthetic HAP material was applied on 32 teeth divided into two groups of 16 teeth each. In one group teeth underwent pulpotomy, in the other high pulpotomy. Evaluation of root growth was recorded from radiographs (pre-treatment, 3 and 12 months following treatment) and by Demjrian's scale for dental maturity and tooth age determination. On the basis of radiographic analysis, immature teeth with affected pulp treated with HAP, both with pulpotomy and high pulpotomy, reached the same stage of root development as control teeth in 50% of cases at 3-months radiographic assessment. After 12 months all tested teeth had the same rate of root development as control teeth, except for 1 of 8 with high pulpotomy. Dentinal bridge was radiographically visible in 50% and 87.5% of pulpotomized teeth after 3 and 12 months, respectively. Neither obliteration of the root canal, presence of denticles nor the presence of deformities in the periapical region were found in any of the observed teeth., Lečenja aficirane pulpe zuba sa nezavršenim rastom korena je još uvek predmet stručnih i naučnih rasprava, između ostalog i zbog neželjenih efekata tradicionalnih preparata na bazi kalcijum hidroksida. Biokeramički materijali se već nekoliko decenija primenjuju u različitim granama medicine, a hidroksiapatit, kao jedna od dve forme kalcijum-fosfatne keramike, ima gotovo istovetan sastav kao neorganski deo kosti, pa je već prihvaćen u endodontskom lečenju zuba sa završ enim rastom korena. Cilj ovog rada je bio da se ispita uticaj hidroksiapatita na apeksogenezu u zuba sa nezavršenim rastom korena i aficiranom pulpom. Ispitivanjem je bilo obuhvaćeno na osam mladih majmuna Cercopithecus Aethiops sa nezavršenim rastom korena zuba. Sintetički hidroksiapatit, veličine čestica od 100 μm je primenjen na trideset dva zuba, podeljenih u dve jednake grupe kod kojih je všena apulpotomija, odnosno visoka pulpotomija. Rendgenološ ka evaluacija rasta korena zuba je vršena pre terapije, kao i tri i dvanaest mesici posle primene HAP, a na osnovu Demjrianove skale za određivanje zrelosti zuba. Na osnovu rendgenološke analize posle 3 meseca je nađeno da je brzina razvoja korena kako pulpotomisanih, tako i visoko pulpotomisanih zuba kod kojih je primenjen HAP bila u 50% slučajeva ista kao kod kontrolnih zuba. Posle 12 meseci stepen razvoja korena zuba je u svih ispitivanih zuba (osim kod jednog od osam zuba sa izvršenom visokom pulpotomijom) bio isti kao u kontrolnih zuba. Dentinski most je bio vidljiv radiološkom analizom u 50% odnosno 87,5% eksperimentalnih zuba posle 3, odnosno posle 12 meseci. Ni u jednom pregledanom zubu rendgenološki nije uočena obliteracija kanala korena, kao ni dentikli ni deformiteti u periapeksnom predelu.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys, Uticaj hidroksiapatita na apeksogenezu u majmuna - klinička studija",
volume = "58",
number = "4",
pages = "395-409",
doi = "10.2298/AVB0804395P"
}

Petrović, V., Marković, D., Čakić, S.,& Krstić, N.. (2008). Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 58(4), 395-409.
https://doi.org/10.2298/AVB0804395P

Petrović V, Marković D, Čakić S, Krstić N. Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys. in Acta veterinaria. 2008;58(4):395-409.
doi:10.2298/AVB0804395P .

Petrović, Vanja, Marković, Dejan, Čakić, Saša, Krstić, N., "Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys" in Acta veterinaria, 58, no. 4 (2008):395-409,
https://doi.org/10.2298/AVB0804395P . .

TY  - JOUR
AU  - Marković, Dejan
AU  - Petrović, Vanja
AU  - Krstić, N.
AU  - Lazarević-Macanović, Mirjana
AU  - Nikolić, Zorana
PY  - 2007
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1321
AB  - The treatment of pulp in teeth with incomplete apex formation is still a clinical challenge. In addition to the most widely used medication for this purpose, calcium hydroxide, other materials have also been tested. Following the use of synthetic biomaterials for restoring bone tissue, and considering their recognized biocompatibility and bioconductivity, our intention was to explore the possibility of using synthetic biomaterials in the endodontic treatment of permanent teeth with incomplete apex formation. The aim of this study was to observe the effectiveness of hydroxyapatite in apexogenesis of young permanent teeth. In this study a 100 µm synthetic hydroxyapatite material, Beohap (HAP) powder, was applied to 24 teeth in 3 dogs of 5.5 months of age, after incomplete root development was established on radiographs. The treated teeth were radiographed monthly and the radiographs compared with those of the corresponding teeth on the other side of the jaw until completion of apex growth. The tested teeth were divided into three groups according to the method of treatment: the first was direct pulp capping, the second was amputation of the pulp at the enamelcement junction and the third was high amputation at the radiographically identified point of root growth. On the basis of radiographic analysis, apex formation was successful in all test groups, with no significant differences between the three groups and the controls (Fisher's and χ 2 test). Deformities of the root apex were observed in two teeth (25%) in the third group.
AB  - Tretman pulpe u vreme kada još uvek traje rast i razvoj korena predstavlja i dalje klinički izazov. Pored kalcijum hidroksida, najčešće i najduže upotrebljavanog medikamenta u ovakvim slučajevima, svakodnevno se testiraju i mnogi drugi materijali. Nakon što su se sintetski biomaterijali pokazali uspešnim u restauraciji koštnog tkiva uz njihovu priznatu biokompatibilnost i biokonduktivnost, naša namera je bila da istražimo mogućnost primene hidroksiapatita kao sintetskog biomaterijala u endodontskom tretmanu zuba sa nezavršenim rastom korena. U ovom istraživanju primenjen je Beohap, sintetski hidroksiapatit, prosečne veličine čestica =100 µm, aplikovan na 24 zuba sa nezavršenim rastom korena kod tri psa uzrasta 5,5 meseci. Uzrorci su kontrolisani radiografski i poređeni sa kontralateralnim netretiranim zubima do završetka rasta korena. Tretirani zubi su podeljeni u tri grupe: u prvoj je urađeno direktno prekrivanje pulpe, u drugoj je pulpa uklonjena do cementno-gleđne granice, a u trećoj je pulpa uklonjena do radiografski vidljivog vrha korena. Na osnovu analize rendgen filmova utvrđeno je da je formiranje vrha korena bilo završeno u sve tri grupe bez statističkih značajnosti razlika (Fisher's i χ 2 testovi) Deformiteti vrha korena uočeni su u 2 uzorka u trećoj grupi (25%).
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - Radiological assessment of apex formation following use of hydroxyapatite
T1  - Rendgenološka procena apeksogeneze nakon primene hidroksiapatita
VL  - 57
IS  - 2-3
SP  - 275
EP  - 287
DO  - 10.2298/AVB0703275M
ER  - 

@article{
author = "Marković, Dejan and Petrović, Vanja and Krstić, N. and Lazarević-Macanović, Mirjana and Nikolić, Zorana",
year = "2007",
abstract = "The treatment of pulp in teeth with incomplete apex formation is still a clinical challenge. In addition to the most widely used medication for this purpose, calcium hydroxide, other materials have also been tested. Following the use of synthetic biomaterials for restoring bone tissue, and considering their recognized biocompatibility and bioconductivity, our intention was to explore the possibility of using synthetic biomaterials in the endodontic treatment of permanent teeth with incomplete apex formation. The aim of this study was to observe the effectiveness of hydroxyapatite in apexogenesis of young permanent teeth. In this study a 100 µm synthetic hydroxyapatite material, Beohap (HAP) powder, was applied to 24 teeth in 3 dogs of 5.5 months of age, after incomplete root development was established on radiographs. The treated teeth were radiographed monthly and the radiographs compared with those of the corresponding teeth on the other side of the jaw until completion of apex growth. The tested teeth were divided into three groups according to the method of treatment: the first was direct pulp capping, the second was amputation of the pulp at the enamelcement junction and the third was high amputation at the radiographically identified point of root growth. On the basis of radiographic analysis, apex formation was successful in all test groups, with no significant differences between the three groups and the controls (Fisher's and χ 2 test). Deformities of the root apex were observed in two teeth (25%) in the third group., Tretman pulpe u vreme kada još uvek traje rast i razvoj korena predstavlja i dalje klinički izazov. Pored kalcijum hidroksida, najčešće i najduže upotrebljavanog medikamenta u ovakvim slučajevima, svakodnevno se testiraju i mnogi drugi materijali. Nakon što su se sintetski biomaterijali pokazali uspešnim u restauraciji koštnog tkiva uz njihovu priznatu biokompatibilnost i biokonduktivnost, naša namera je bila da istražimo mogućnost primene hidroksiapatita kao sintetskog biomaterijala u endodontskom tretmanu zuba sa nezavršenim rastom korena. U ovom istraživanju primenjen je Beohap, sintetski hidroksiapatit, prosečne veličine čestica =100 µm, aplikovan na 24 zuba sa nezavršenim rastom korena kod tri psa uzrasta 5,5 meseci. Uzrorci su kontrolisani radiografski i poređeni sa kontralateralnim netretiranim zubima do završetka rasta korena. Tretirani zubi su podeljeni u tri grupe: u prvoj je urađeno direktno prekrivanje pulpe, u drugoj je pulpa uklonjena do cementno-gleđne granice, a u trećoj je pulpa uklonjena do radiografski vidljivog vrha korena. Na osnovu analize rendgen filmova utvrđeno je da je formiranje vrha korena bilo završeno u sve tri grupe bez statističkih značajnosti razlika (Fisher's i χ 2 testovi) Deformiteti vrha korena uočeni su u 2 uzorka u trećoj grupi (25%).",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "Radiological assessment of apex formation following use of hydroxyapatite, Rendgenološka procena apeksogeneze nakon primene hidroksiapatita",
volume = "57",
number = "2-3",
pages = "275-287",
doi = "10.2298/AVB0703275M"
}

Marković, D., Petrović, V., Krstić, N., Lazarević-Macanović, M.,& Nikolić, Z.. (2007). Radiological assessment of apex formation following use of hydroxyapatite. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 57(2-3), 275-287.
https://doi.org/10.2298/AVB0703275M

Marković D, Petrović V, Krstić N, Lazarević-Macanović M, Nikolić Z. Radiological assessment of apex formation following use of hydroxyapatite. in Acta veterinaria. 2007;57(2-3):275-287.
doi:10.2298/AVB0703275M .

Marković, Dejan, Petrović, Vanja, Krstić, N., Lazarević-Macanović, Mirjana, Nikolić, Zorana, "Radiological assessment of apex formation following use of hydroxyapatite" in Acta veterinaria, 57, no. 2-3 (2007):275-287,
https://doi.org/10.2298/AVB0703275M . .

TY  - JOUR
AU  - Krstić, N
AU  - Milosavljević, Željko
AU  - Nikolić, Predrag
AU  - Janković-Zagorcić, A
PY  - 1999
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1102
AB  - Viscerocranium condition and development teleroentgen analyses have been avoided for quite a long time, mostly due to the technical impossibility of proper fixation of animals during recording and numerous differences in defining reference proints for linear and angular measurements. Since the available literature offeredus such field data only from research on monkeys, and since there is no ideal standard for the German shepherd dog breed but only numerous variations, we have attemated to standardize elements (points) which relate the skeleton structure and teeth to other cranium bone elements. A total of 15 German shepherd dogs, 12 months old and of body mass 25-30 kilograma, was examined and the results of teleroentgen analyses were checked on skull preparations after killing the animals. The most important radiocraniommetric points on the profile x-ray of a 12 months old German shepherd dog which could be used as reference parameters in the teleroentgenogram analyses are Nasion - N, Spina nasalis anterior - SnA, point A, Prosthion - Pr, Infradentale - Id, Pogonion - Pg, Gnathion - Gn, Menton - Mn, point Sella - S, Basion - Ba, Spina nasalis posterior - SnP, Porion -Po, Orbitale - Or, Gonion - Go, Articulare - Ar and Condylion - Co. Dog head point H and point Iv were taken as typical points for the mesocephal type of dog without analogy with human medicine. Studying the x-rays in sagittal or frontal dog head projection,. we determined the most important radiocraniometric points of importance for the formulation of regular interrelationships of certain regions of the neuroviscerocranium: Zygion - Zy, Eurion - Eu, Ectomaxillare - Em, Ectomalare - ecm, points Eim, fin, and the points Ecm, Ecp, Ecl and En were characteristic only for veterinary radiocraniometry. The following soft tissue points were detemined after analysis of the dog head skin profile by the radiocephalometric method. Glabela -G, Nasion - Na', Pronasale - Prn', Labrale superior - Ls', Labrale inferior - Li', Supramentale - Sm', Pogonion - Pg', Gnathion - Gn', and the following points were derived for the first time without any analogy with human radiocephalometry: Dorsum - D', Prosthion - Pr', Menthon - M' and the point in the Iv' vasorum incisure. The derived radiocephalometric points on the dog head frontal x-ray were: Zygion - Zy'. Eurion - Eu', ectomalare - ecm; point en' and Rostrum - R'.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria
T1  - Roentgen-craniometric and roentgen-cephalometric analysis of points on the German shepherd dog breed
VL  - 49
IS  - 2-3
SP  - 185
EP  - 198
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_117
ER  - 

@article{
author = "Krstić, N and Milosavljević, Željko and Nikolić, Predrag and Janković-Zagorcić, A",
year = "1999",
abstract = "Viscerocranium condition and development teleroentgen analyses have been avoided for quite a long time, mostly due to the technical impossibility of proper fixation of animals during recording and numerous differences in defining reference proints for linear and angular measurements. Since the available literature offeredus such field data only from research on monkeys, and since there is no ideal standard for the German shepherd dog breed but only numerous variations, we have attemated to standardize elements (points) which relate the skeleton structure and teeth to other cranium bone elements. A total of 15 German shepherd dogs, 12 months old and of body mass 25-30 kilograma, was examined and the results of teleroentgen analyses were checked on skull preparations after killing the animals. The most important radiocraniommetric points on the profile x-ray of a 12 months old German shepherd dog which could be used as reference parameters in the teleroentgenogram analyses are Nasion - N, Spina nasalis anterior - SnA, point A, Prosthion - Pr, Infradentale - Id, Pogonion - Pg, Gnathion - Gn, Menton - Mn, point Sella - S, Basion - Ba, Spina nasalis posterior - SnP, Porion -Po, Orbitale - Or, Gonion - Go, Articulare - Ar and Condylion - Co. Dog head point H and point Iv were taken as typical points for the mesocephal type of dog without analogy with human medicine. Studying the x-rays in sagittal or frontal dog head projection,. we determined the most important radiocraniometric points of importance for the formulation of regular interrelationships of certain regions of the neuroviscerocranium: Zygion - Zy, Eurion - Eu, Ectomaxillare - Em, Ectomalare - ecm, points Eim, fin, and the points Ecm, Ecp, Ecl and En were characteristic only for veterinary radiocraniometry. The following soft tissue points were detemined after analysis of the dog head skin profile by the radiocephalometric method. Glabela -G, Nasion - Na', Pronasale - Prn', Labrale superior - Ls', Labrale inferior - Li', Supramentale - Sm', Pogonion - Pg', Gnathion - Gn', and the following points were derived for the first time without any analogy with human radiocephalometry: Dorsum - D', Prosthion - Pr', Menthon - M' and the point in the Iv' vasorum incisure. The derived radiocephalometric points on the dog head frontal x-ray were: Zygion - Zy'. Eurion - Eu', ectomalare - ecm; point en' and Rostrum - R'.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria",
title = "Roentgen-craniometric and roentgen-cephalometric analysis of points on the German shepherd dog breed",
volume = "49",
number = "2-3",
pages = "185-198",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_117"
}

Krstić, N., Milosavljević, Ž., Nikolić, P.,& Janković-Zagorcić, A.. (1999). Roentgen-craniometric and roentgen-cephalometric analysis of points on the German shepherd dog breed. in Acta Veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 49(2-3), 185-198.
https://hdl.handle.net/21.15107/rcub_veterinar_117

Krstić N, Milosavljević Ž, Nikolić P, Janković-Zagorcić A. Roentgen-craniometric and roentgen-cephalometric analysis of points on the German shepherd dog breed. in Acta Veterinaria. 1999;49(2-3):185-198.
https://hdl.handle.net/21.15107/rcub_veterinar_117 .

Krstić, N, Milosavljević, Željko, Nikolić, Predrag, Janković-Zagorcić, A, "Roentgen-craniometric and roentgen-cephalometric analysis of points on the German shepherd dog breed" in Acta Veterinaria, 49, no. 2-3 (1999):185-198,
https://hdl.handle.net/21.15107/rcub_veterinar_117 .