TY  - JOUR
AU  - Kovačević, Bojan
AU  - Ignjatović, M.
AU  - Ćuk, Vladimir
AU  - Živaljević, Vladan
AU  - Paunović, Ivan
PY  - 2011
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1662
AB  - Background : Hypocalcemia is the most common postoperative complication after total thyroidectomy. The aim of this prospective study was to determine biochemical parameters in the early postoperative period that could identify patients with significantly increased risk of symptomatic hypocalcemia development. Methods : The study included 100 individuals undergoing total thyroidectomy from January to May 2009. In all patients PTH, calcium, inorganic phosphate, magnesium, and albumin levels were measured immediately preoperatively, 30 minutes postoperatively and every morning for the following five days. Results : Clinically significant hypocalcemia was observed in 19% of all cases. Fall of the iPTH values by more than 88% from preoperative values, 30 min after completion of the surgery, showed 100% sensitivity and 100% specificity for the occurrence of symptomatic hypocalcemia. Conclusions : According to our results immediate postoperative measurement of the iPTH may be considered as a useful method to predict with high certainty which patients will need calcium supplementation, and to separate them from patients who can be safely and early discharged.
PB  - Acta Medical Belgica, Brussels
T2  - Acta Chirurgica Belgica
T1  - Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy
VL  - 111
IS  - 5
SP  - 303
EP  - 307
DO  - 10.1080/00015458.2011.11680758
ER  - 

@article{
author = "Kovačević, Bojan and Ignjatović, M. and Ćuk, Vladimir and Živaljević, Vladan and Paunović, Ivan",
year = "2011",
abstract = "Background : Hypocalcemia is the most common postoperative complication after total thyroidectomy. The aim of this prospective study was to determine biochemical parameters in the early postoperative period that could identify patients with significantly increased risk of symptomatic hypocalcemia development. Methods : The study included 100 individuals undergoing total thyroidectomy from January to May 2009. In all patients PTH, calcium, inorganic phosphate, magnesium, and albumin levels were measured immediately preoperatively, 30 minutes postoperatively and every morning for the following five days. Results : Clinically significant hypocalcemia was observed in 19% of all cases. Fall of the iPTH values by more than 88% from preoperative values, 30 min after completion of the surgery, showed 100% sensitivity and 100% specificity for the occurrence of symptomatic hypocalcemia. Conclusions : According to our results immediate postoperative measurement of the iPTH may be considered as a useful method to predict with high certainty which patients will need calcium supplementation, and to separate them from patients who can be safely and early discharged.",
publisher = "Acta Medical Belgica, Brussels",
journal = "Acta Chirurgica Belgica",
title = "Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy",
volume = "111",
number = "5",
pages = "303-307",
doi = "10.1080/00015458.2011.11680758"
}

Kovačević, B., Ignjatović, M., Ćuk, V., Živaljević, V.,& Paunović, I.. (2011). Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy. in Acta Chirurgica Belgica
Acta Medical Belgica, Brussels., 111(5), 303-307.
https://doi.org/10.1080/00015458.2011.11680758

Kovačević B, Ignjatović M, Ćuk V, Živaljević V, Paunović I. Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy. in Acta Chirurgica Belgica. 2011;111(5):303-307.
doi:10.1080/00015458.2011.11680758 .

Kovačević, Bojan, Ignjatović, M., Ćuk, Vladimir, Živaljević, Vladan, Paunović, Ivan, "Early Prediction of Symptomatic Hypocalcemia after Total Thyroidectomy" in Acta Chirurgica Belgica, 111, no. 5 (2011):303-307,
https://doi.org/10.1080/00015458.2011.11680758 . .