TY  - JOUR
AU  - Jekić, B.
AU  - Novaković, I.
AU  - Luković, L
AU  - Kuzmanović, M
AU  - Popović, Branka
AU  - Milašin, Jelena
AU  - Bunjevacki, G
AU  - Damnjanović, Tatjana
AU  - Cvjetičanin, S
AU  - Bunjevački, Vera
PY  - 2006
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1314
AB  - Myelodysplastic syndromes (MDS) are rare disorders in children. Molecular mechanisims underlying MDS in children are not yet completely understood. Considering the role of FMS and TP53 gene mutations in adult MDS patients, we analyzed nnutations of these genes in a cohort of 35 children with MDS. Single-strand conformation polymorphism polymerase chain reaction analysis performed on FMS codon 969 and TP53 exons 5-9 showed no mutations in the analyzed sequences. Our results Suggest that molecular mechanisms of MDS evolution in children are different from those in adults.
PB  - Elsevier Science Inc, New York
T2  - Cancer Genetics & Cytogenetics
T1  - Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome
VL  - 166
IS  - 2
SP  - 163
EP  - 165
DO  - 10.1016/j.cancergencyto.2005.11.003
ER  - 

@article{
author = "Jekić, B. and Novaković, I. and Luković, L and Kuzmanović, M and Popović, Branka and Milašin, Jelena and Bunjevacki, G and Damnjanović, Tatjana and Cvjetičanin, S and Bunjevački, Vera",
year = "2006",
abstract = "Myelodysplastic syndromes (MDS) are rare disorders in children. Molecular mechanisims underlying MDS in children are not yet completely understood. Considering the role of FMS and TP53 gene mutations in adult MDS patients, we analyzed nnutations of these genes in a cohort of 35 children with MDS. Single-strand conformation polymorphism polymerase chain reaction analysis performed on FMS codon 969 and TP53 exons 5-9 showed no mutations in the analyzed sequences. Our results Suggest that molecular mechanisms of MDS evolution in children are different from those in adults.",
publisher = "Elsevier Science Inc, New York",
journal = "Cancer Genetics & Cytogenetics",
title = "Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome",
volume = "166",
number = "2",
pages = "163-165",
doi = "10.1016/j.cancergencyto.2005.11.003"
}

Jekić, B., Novaković, I., Luković, L., Kuzmanović, M., Popović, B., Milašin, J., Bunjevacki, G., Damnjanović, T., Cvjetičanin, S.,& Bunjevački, V.. (2006). Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome. in Cancer Genetics & Cytogenetics
Elsevier Science Inc, New York., 166(2), 163-165.
https://doi.org/10.1016/j.cancergencyto.2005.11.003

Jekić B, Novaković I, Luković L, Kuzmanović M, Popović B, Milašin J, Bunjevacki G, Damnjanović T, Cvjetičanin S, Bunjevački V. Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome. in Cancer Genetics & Cytogenetics. 2006;166(2):163-165.
doi:10.1016/j.cancergencyto.2005.11.003 .

Jekić, B., Novaković, I., Luković, L, Kuzmanović, M, Popović, Branka, Milašin, Jelena, Bunjevacki, G, Damnjanović, Tatjana, Cvjetičanin, S, Bunjevački, Vera, "Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome" in Cancer Genetics & Cytogenetics, 166, no. 2 (2006):163-165,
https://doi.org/10.1016/j.cancergencyto.2005.11.003 . .

TY  - JOUR
AU  - Jekić, B.
AU  - Novaković, I.
AU  - Luković, L
AU  - Kuzmanović, M
AU  - Popović, Branka
AU  - Pastar, I
AU  - Milašin, Jelena
AU  - Bunjevacki, G
AU  - Bunjevački, Vera
PY  - 2004
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1224
AB  - In children, myelodysplastic syndromes (MDS) represent less then 10% of all hematological malignancies; consequently, molecular genetic studies dealing with this group of patients are scarce. We have analyzed 35 archival bone marrow samples of children with MDS for the presence of mutations in the first and second exons of the NRAS and KRAS2 genes. Mutations were detected with single-strand conformation polymorphism analysis in three patients. One patient harbored a mutation in the second exon of NRAS and two patients in the second exon of KRAS2. Sequencing was performed in two samples and novel mutations were found in both. One patient had a missense mutation in codon 45 of NRAS; the other had a silent mutation in codon 53 and a missense mutation in codon 55 of KRAS2.
PB  - Elsevier Science Inc, New York
T2  - Cancer Genetics & Cytogenetics
T1  - Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes
VL  - 154
IS  - 2
SP  - 180
EP  - 182
DO  - 10.1016/j.cancergencyto.2004.02.025
ER  - 

@article{
author = "Jekić, B. and Novaković, I. and Luković, L and Kuzmanović, M and Popović, Branka and Pastar, I and Milašin, Jelena and Bunjevacki, G and Bunjevački, Vera",
year = "2004",
abstract = "In children, myelodysplastic syndromes (MDS) represent less then 10% of all hematological malignancies; consequently, molecular genetic studies dealing with this group of patients are scarce. We have analyzed 35 archival bone marrow samples of children with MDS for the presence of mutations in the first and second exons of the NRAS and KRAS2 genes. Mutations were detected with single-strand conformation polymorphism analysis in three patients. One patient harbored a mutation in the second exon of NRAS and two patients in the second exon of KRAS2. Sequencing was performed in two samples and novel mutations were found in both. One patient had a missense mutation in codon 45 of NRAS; the other had a silent mutation in codon 53 and a missense mutation in codon 55 of KRAS2.",
publisher = "Elsevier Science Inc, New York",
journal = "Cancer Genetics & Cytogenetics",
title = "Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes",
volume = "154",
number = "2",
pages = "180-182",
doi = "10.1016/j.cancergencyto.2004.02.025"
}

Jekić, B., Novaković, I., Luković, L., Kuzmanović, M., Popović, B., Pastar, I., Milašin, J., Bunjevacki, G.,& Bunjevački, V.. (2004). Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes. in Cancer Genetics & Cytogenetics
Elsevier Science Inc, New York., 154(2), 180-182.
https://doi.org/10.1016/j.cancergencyto.2004.02.025

Jekić B, Novaković I, Luković L, Kuzmanović M, Popović B, Pastar I, Milašin J, Bunjevacki G, Bunjevački V. Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes. in Cancer Genetics & Cytogenetics. 2004;154(2):180-182.
doi:10.1016/j.cancergencyto.2004.02.025 .

Jekić, B., Novaković, I., Luković, L, Kuzmanović, M, Popović, Branka, Pastar, I, Milašin, Jelena, Bunjevacki, G, Bunjevački, Vera, "Low frequency of NRAS and KRAS2 gene mutations in childhood myelodysplastic syndromes" in Cancer Genetics & Cytogenetics, 154, no. 2 (2004):180-182,
https://doi.org/10.1016/j.cancergencyto.2004.02.025 . .