TY  - JOUR
AU  - Kadović, Jana
AU  - Novaković, Nada
AU  - Vučković, Mila
AU  - Đorđević, Vladan
AU  - Petrović, Vanja
AU  - Stojčev-Stajčić, Ljiljana
AU  - Čakić, Saša
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2447
AB  - Background/Aim. Knowledge of numerous variations in anatomical features of furcation area is a prerequisite for the achievement of more predictable results in the therapy of multi-rooted teeth with furcation involvement (FI). The aim of the study was to evaluate the morphological characteristics of extracted molars of adult population in Belgrade, Serbia. Methods. In total, 468 extracted first and second molars, both mandibular and maxillary, were measured. The values of root trunk lengths and root lengths, diameter of furcation entrances (FE), distance between the roots and depth of root concavity were analysed. Results. The maxillary first molars had significantly higher root trunk lengths values than the second molars. As for the mandibular molars, FE was smaller than 1 mm. The distance between the roots was more than 2 mm at the third level of measurement. Conclusion. The buccal FE of maxillary molars was the lowest. The root concavity of the second mandibular molars was higher from the lingual aspect.
AB  - Uvod/Cilj. Poznavanje mnogobrojnih varijacija anatomskih karakteristika furkacija (furkacionih regija) je preduslov za postizanje predvidivih rezultata terapije furkacionih defekata višekorenih zuba. Cilj ovog istraživanja je bio procena morfološke karakteristike izvađenih zuba adultne populacije u Beogradu. Metode. Merenja su vršena na ukupno 468 izvađenih prvih i drugih molara i gornje i donje vilice. Analizirane su izmerene vrednosti dužine korenskog stabla i dužine korenova, prečnik ulaza u furkaciju, odstojanje između korenova i dubina korenskog konkaviteta. Rezultati. Prvi gornji molari su imali signifikantno veće vrednosti dužine korenskog stabla od drugih gornjih molara. Kod donjih molara, prečnik ulaska u furkaciju bio je manji od 1 mm. Na trećem nivou merenja, odstojanje između korenova imalo je vrednost veću od 2 mm. Zaključak. Prečnik ulaska u furkaciju sa bukalne strane gornjih molara bio je najmanji. Dubina korenskog konkaviteta drugih donjih molara bila je veća sa lingvalne strane.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study
T1  - Anatomske karakteristike furkacija i korenova višekorenih zuba - epidemiološka studija
VL  - 76
IS  - 8
SP  - 761
EP  - 771
DO  - 10.2298/VSP170308149K
ER  - 

@article{
author = "Kadović, Jana and Novaković, Nada and Vučković, Mila and Đorđević, Vladan and Petrović, Vanja and Stojčev-Stajčić, Ljiljana and Čakić, Saša",
year = "2019",
abstract = "Background/Aim. Knowledge of numerous variations in anatomical features of furcation area is a prerequisite for the achievement of more predictable results in the therapy of multi-rooted teeth with furcation involvement (FI). The aim of the study was to evaluate the morphological characteristics of extracted molars of adult population in Belgrade, Serbia. Methods. In total, 468 extracted first and second molars, both mandibular and maxillary, were measured. The values of root trunk lengths and root lengths, diameter of furcation entrances (FE), distance between the roots and depth of root concavity were analysed. Results. The maxillary first molars had significantly higher root trunk lengths values than the second molars. As for the mandibular molars, FE was smaller than 1 mm. The distance between the roots was more than 2 mm at the third level of measurement. Conclusion. The buccal FE of maxillary molars was the lowest. The root concavity of the second mandibular molars was higher from the lingual aspect., Uvod/Cilj. Poznavanje mnogobrojnih varijacija anatomskih karakteristika furkacija (furkacionih regija) je preduslov za postizanje predvidivih rezultata terapije furkacionih defekata višekorenih zuba. Cilj ovog istraživanja je bio procena morfološke karakteristike izvađenih zuba adultne populacije u Beogradu. Metode. Merenja su vršena na ukupno 468 izvađenih prvih i drugih molara i gornje i donje vilice. Analizirane su izmerene vrednosti dužine korenskog stabla i dužine korenova, prečnik ulaza u furkaciju, odstojanje između korenova i dubina korenskog konkaviteta. Rezultati. Prvi gornji molari su imali signifikantno veće vrednosti dužine korenskog stabla od drugih gornjih molara. Kod donjih molara, prečnik ulaska u furkaciju bio je manji od 1 mm. Na trećem nivou merenja, odstojanje između korenova imalo je vrednost veću od 2 mm. Zaključak. Prečnik ulaska u furkaciju sa bukalne strane gornjih molara bio je najmanji. Dubina korenskog konkaviteta drugih donjih molara bila je veća sa lingvalne strane.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study, Anatomske karakteristike furkacija i korenova višekorenih zuba - epidemiološka studija",
volume = "76",
number = "8",
pages = "761-771",
doi = "10.2298/VSP170308149K"
}

Kadović, J., Novaković, N., Vučković, M., Đorđević, V., Petrović, V., Stojčev-Stajčić, L.,& Čakić, S.. (2019). Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(8), 761-771.
https://doi.org/10.2298/VSP170308149K

Kadović J, Novaković N, Vučković M, Đorđević V, Petrović V, Stojčev-Stajčić L, Čakić S. Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study. in Vojnosanitetski pregled. 2019;76(8):761-771.
doi:10.2298/VSP170308149K .

Kadović, Jana, Novaković, Nada, Vučković, Mila, Đorđević, Vladan, Petrović, Vanja, Stojčev-Stajčić, Ljiljana, Čakić, Saša, "Anatomical characteristics of the furcation area and root surfaces of multi-rooted teeth: Epidemiological study" in Vojnosanitetski pregled, 76, no. 8 (2019):761-771,
https://doi.org/10.2298/VSP170308149K . .

TY  - JOUR
AU  - Đorđević, Vladan
AU  - Vučković, Mila
AU  - Joksimović, Ena
AU  - Asotić, Amina
AU  - Stašević, Milena
AU  - Asotić, Jasminka
AU  - Petrović, Vanja
AU  - Stašević-Karličić, Ivana
PY  - 2019
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2429
AB  - Introduction Patients with schizophrenia are likely to constitute a high-risk group of individuals with respect to prevalence of oral diseases and they require special attention. Factors like nature of psychiatric disorders, length of stay and oral-side effects of psychotropic medications have been noted as contributors to poor oral health among institutionalized chronic psychiatric patients. Methods This cross-sectional study comprised 190 inpatients with schizophrenia at the Dr Laza Lazarevic Clinic for Mental Disorders in Belgrade, and 190 mentally healthy patients at the Clinic for Periodontology and Oral Medicine, School of Dental Medicine, University of Belgrade. A questionnaire was designed for the purpose of this research with the aim of recording information on demographic data (age and sex), unhealthy habits (tobacco smoking, alcohol consumption and drug abuse), and data about the existence of any oral symptom and/or sings related to oral soft tissue pathology. All participants were subjected to targeted clinical examinations. Results All study group patients were receiving psychotropic medications (mean number 4.18 ± 1.14; from 1 to 7 medications). The study group patients had a total of 272 symptoms and 121 signs of oral disorders; which was almost four times higher for symptoms and even nine times higher for signs of oral disorders than in the control group. Conclusion Schizophrenia as a mental disorder does not directly affect the condition of oral health of this group of psychiatric patients, but indirectly - reducing their motivation and awareness of the importance of oral health, which is particularly emphasized in hospital conditions.
AB  - Uvod Hospitalizovani bolesnici sa shizofrenijom mogu da predstavljaju visoko rizičnu grupu osoba sa aspekta prevalencije oralnih oboljenja, te zahtevaju posebnu pažnju. Faktori poput prirode psihijatrijske bolesti, dužine hospitalizacije i neželjenih efekata psihotropnih medikamenata utiču na loše oralno zdravlje hospitalizovanih hroničnih psihijatrijskih bolesnika. Metode Ova studija preseka obuhvatila je 190 bolesnika sa shizofrenijom hospitalizovanih u Klinici za psihijatrijske bolesti "Dr Laza Lazarević" u Beogradu i 190 mentalno zdravih bolesnika Klinike za paradontologiju i oralnu medicinu Stomatološkog fakulteta Univerziteta u Beogradu. U svrhu ovog istraživanja dizajniran je upitnik sa ciljem beleženja demografskih podataka (starost i pol), loših navika (pušenje duvana, konzumiranje alkohola i zloupotreba droga) i podataka o postojanju bilo kojeg oralnog simptoma i/ili znaka koji se odnosi na patologiju mekih tkiva usne duplje. Svi učesnici bili su podvrgnuti ciljanim kliničkim pregledima. Rezultati Svi bolesnici iz studijske grupe primali su psihotropne lekove (srednja vrednost 4,18 ± 1,14, od jednog do sedam lekova). Bolesnici studijske grupe imali su ukupno 272 oralna simptoma i 121 znak oralnih oboljenja, što je skoro četiri puta više za oralne simptome, a čak i devet puta više za znake oralnih poremećaja nego u kontrolnoj grupi. Zaključak Shizofrenija kao mentalni poremećaj ne utiče direktno na stanje oralnog zdravlja ove grupe psihijatrijskih bolesnika, već indirektno - smanjujući im motivaciju i svest o značaju oralnog zdravlja, posebno u bolničkim uslovima.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia
T1  - Procena simptoma i znakova oralnih mekotkivnih poremećaja kod hospitalizovanih bolesnika sa shizofrenijom
VL  - 147
IS  - 5-6
SP  - 276
EP  - 280
DO  - 10.2298/SARH190311042D
ER  - 

@article{
author = "Đorđević, Vladan and Vučković, Mila and Joksimović, Ena and Asotić, Amina and Stašević, Milena and Asotić, Jasminka and Petrović, Vanja and Stašević-Karličić, Ivana",
year = "2019",
abstract = "Introduction Patients with schizophrenia are likely to constitute a high-risk group of individuals with respect to prevalence of oral diseases and they require special attention. Factors like nature of psychiatric disorders, length of stay and oral-side effects of psychotropic medications have been noted as contributors to poor oral health among institutionalized chronic psychiatric patients. Methods This cross-sectional study comprised 190 inpatients with schizophrenia at the Dr Laza Lazarevic Clinic for Mental Disorders in Belgrade, and 190 mentally healthy patients at the Clinic for Periodontology and Oral Medicine, School of Dental Medicine, University of Belgrade. A questionnaire was designed for the purpose of this research with the aim of recording information on demographic data (age and sex), unhealthy habits (tobacco smoking, alcohol consumption and drug abuse), and data about the existence of any oral symptom and/or sings related to oral soft tissue pathology. All participants were subjected to targeted clinical examinations. Results All study group patients were receiving psychotropic medications (mean number 4.18 ± 1.14; from 1 to 7 medications). The study group patients had a total of 272 symptoms and 121 signs of oral disorders; which was almost four times higher for symptoms and even nine times higher for signs of oral disorders than in the control group. Conclusion Schizophrenia as a mental disorder does not directly affect the condition of oral health of this group of psychiatric patients, but indirectly - reducing their motivation and awareness of the importance of oral health, which is particularly emphasized in hospital conditions., Uvod Hospitalizovani bolesnici sa shizofrenijom mogu da predstavljaju visoko rizičnu grupu osoba sa aspekta prevalencije oralnih oboljenja, te zahtevaju posebnu pažnju. Faktori poput prirode psihijatrijske bolesti, dužine hospitalizacije i neželjenih efekata psihotropnih medikamenata utiču na loše oralno zdravlje hospitalizovanih hroničnih psihijatrijskih bolesnika. Metode Ova studija preseka obuhvatila je 190 bolesnika sa shizofrenijom hospitalizovanih u Klinici za psihijatrijske bolesti "Dr Laza Lazarević" u Beogradu i 190 mentalno zdravih bolesnika Klinike za paradontologiju i oralnu medicinu Stomatološkog fakulteta Univerziteta u Beogradu. U svrhu ovog istraživanja dizajniran je upitnik sa ciljem beleženja demografskih podataka (starost i pol), loših navika (pušenje duvana, konzumiranje alkohola i zloupotreba droga) i podataka o postojanju bilo kojeg oralnog simptoma i/ili znaka koji se odnosi na patologiju mekih tkiva usne duplje. Svi učesnici bili su podvrgnuti ciljanim kliničkim pregledima. Rezultati Svi bolesnici iz studijske grupe primali su psihotropne lekove (srednja vrednost 4,18 ± 1,14, od jednog do sedam lekova). Bolesnici studijske grupe imali su ukupno 272 oralna simptoma i 121 znak oralnih oboljenja, što je skoro četiri puta više za oralne simptome, a čak i devet puta više za znake oralnih poremećaja nego u kontrolnoj grupi. Zaključak Shizofrenija kao mentalni poremećaj ne utiče direktno na stanje oralnog zdravlja ove grupe psihijatrijskih bolesnika, već indirektno - smanjujući im motivaciju i svest o značaju oralnog zdravlja, posebno u bolničkim uslovima.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia, Procena simptoma i znakova oralnih mekotkivnih poremećaja kod hospitalizovanih bolesnika sa shizofrenijom",
volume = "147",
number = "5-6",
pages = "276-280",
doi = "10.2298/SARH190311042D"
}

Đorđević, V., Vučković, M., Joksimović, E., Asotić, A., Stašević, M., Asotić, J., Petrović, V.,& Stašević-Karličić, I.. (2019). Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 147(5-6), 276-280.
https://doi.org/10.2298/SARH190311042D

Đorđević V, Vučković M, Joksimović E, Asotić A, Stašević M, Asotić J, Petrović V, Stašević-Karličić I. Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia. in Srpski arhiv za celokupno lekarstvo. 2019;147(5-6):276-280.
doi:10.2298/SARH190311042D .

Đorđević, Vladan, Vučković, Mila, Joksimović, Ena, Asotić, Amina, Stašević, Milena, Asotić, Jasminka, Petrović, Vanja, Stašević-Karličić, Ivana, "Evaluation of symptoms and sings of oral soft tissue disorders among inpatients with schizophrenia" in Srpski arhiv za celokupno lekarstvo, 147, no. 5-6 (2019):276-280,
https://doi.org/10.2298/SARH190311042D . .

TY  - JOUR
AU  - Pejčić, Nataša
AU  - Petrović, Vanja
AU  - Marković, Dejan
AU  - Miličić, Biljana
AU  - Ilic-Dimitrijević, Ivana
AU  - Perunović, Neda
AU  - Čakić, Saša
PY  - 2017
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2205
AB  - BACKGROUND: Dentists have a high prevalence of musculoskeletal (MS) pain, which is the most common symptom associated with work-related musculoskeletal disorders (WMSDs). To overcome this problem, identification of the risk factors and preventive measures for MS pain are of paramount importance to dentists in order to improve their quality of life and work. OBJECTIVES: The aims of this study were to recognize the risk factors for MS pain and their impact on dental work, as well as to identify preventive measures of MS pain among dentists. METHODS: Self-reporting questionnaire consisting of 78 questions was exclusively developed for the study and sent to 500 working active dentists in Serbia. RESULTS: Response rate was 71.2% (356 dentists). The prevalence of MS pain was 82.6% among dentists. The main risk factors for MS pain were advanced age, female dentists, presence of chronic diseases, long working hours, and high frequency of treated patients. The most effective preventive measures in preventing MS pain were massage treatments and physical activities. Followed by use of ergonomically designed equipment, correct and dynamic working positions, and an adequate workflow organization. CONCLUSION: The risk factors for MS pain and their impact on dental work should widely be disseminated among dentists. Importantly, proper implementation in everyday life of adequate preventive measures is essential for preventing MS pain and development of WMSDs.
PB  - Ios Press, Amsterdam
T2  - Work - A Journal of Prevention Assessment & Rehabilitation
T1  - Assessment of risk factors and preventive measures and their relations to work-related musculoskeletal pain among dentists
VL  - 57
IS  - 4
SP  - 573
EP  - 593
DO  - 10.3233/WOR-172588
ER  - 

@article{
author = "Pejčić, Nataša and Petrović, Vanja and Marković, Dejan and Miličić, Biljana and Ilic-Dimitrijević, Ivana and Perunović, Neda and Čakić, Saša",
year = "2017",
abstract = "BACKGROUND: Dentists have a high prevalence of musculoskeletal (MS) pain, which is the most common symptom associated with work-related musculoskeletal disorders (WMSDs). To overcome this problem, identification of the risk factors and preventive measures for MS pain are of paramount importance to dentists in order to improve their quality of life and work. OBJECTIVES: The aims of this study were to recognize the risk factors for MS pain and their impact on dental work, as well as to identify preventive measures of MS pain among dentists. METHODS: Self-reporting questionnaire consisting of 78 questions was exclusively developed for the study and sent to 500 working active dentists in Serbia. RESULTS: Response rate was 71.2% (356 dentists). The prevalence of MS pain was 82.6% among dentists. The main risk factors for MS pain were advanced age, female dentists, presence of chronic diseases, long working hours, and high frequency of treated patients. The most effective preventive measures in preventing MS pain were massage treatments and physical activities. Followed by use of ergonomically designed equipment, correct and dynamic working positions, and an adequate workflow organization. CONCLUSION: The risk factors for MS pain and their impact on dental work should widely be disseminated among dentists. Importantly, proper implementation in everyday life of adequate preventive measures is essential for preventing MS pain and development of WMSDs.",
publisher = "Ios Press, Amsterdam",
journal = "Work - A Journal of Prevention Assessment & Rehabilitation",
title = "Assessment of risk factors and preventive measures and their relations to work-related musculoskeletal pain among dentists",
volume = "57",
number = "4",
pages = "573-593",
doi = "10.3233/WOR-172588"
}

Pejčić, N., Petrović, V., Marković, D., Miličić, B., Ilic-Dimitrijević, I., Perunović, N.,& Čakić, S.. (2017). Assessment of risk factors and preventive measures and their relations to work-related musculoskeletal pain among dentists. in Work - A Journal of Prevention Assessment & Rehabilitation
Ios Press, Amsterdam., 57(4), 573-593.
https://doi.org/10.3233/WOR-172588

Pejčić N, Petrović V, Marković D, Miličić B, Ilic-Dimitrijević I, Perunović N, Čakić S. Assessment of risk factors and preventive measures and their relations to work-related musculoskeletal pain among dentists. in Work - A Journal of Prevention Assessment & Rehabilitation. 2017;57(4):573-593.
doi:10.3233/WOR-172588 .

Pejčić, Nataša, Petrović, Vanja, Marković, Dejan, Miličić, Biljana, Ilic-Dimitrijević, Ivana, Perunović, Neda, Čakić, Saša, "Assessment of risk factors and preventive measures and their relations to work-related musculoskeletal pain among dentists" in Work - A Journal of Prevention Assessment & Rehabilitation, 57, no. 4 (2017):573-593,
https://doi.org/10.3233/WOR-172588 . .

TY  - JOUR
AU  - Petrović, Vanja
AU  - Pejčić, Nataša
AU  - Bulat, Petar
AU  - Đurić-Jovičić, Milica
AU  - Miljković, Nadica
AU  - Marković, Dejan
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2176
AB  - Aim: The purpose was to assess ergonomic risk level in dentistry, which may contribute to manifestation of musculoskeletal disorders (MSD). Methods and Materials: The study included ten dentists, postgraduate students, mean age (33 ± 3.4). Participants were asked to perform typical dental examination in standing and sitting positions. The surface electromyography (EMG) was recorded during dental work from both left and right shoulder muscles: descendent trapezius muscle (T); back muscles: erector spinae muscle (ES); and neck muscles: sternocleidomastoid muscle (SCM) and splenius capitis muscle (SC). Results: High muscles forces, greater than 21% of the maximal voluntary contraction (MVC), which could be indicative of high risk, particularly occurred in muscles SC on both sides of the body in the sitting position. The medium risk level occurred in the same muscles on both sides in standing position. Left and right T muscles were under medium ergonomic risk level in both, sitting and standing working positions. SCM muscles on the left and right side of the body in both working positions were under low risk level, lower than 10% of the MVC. In sitting position, medium risk level occurred in ES muscles on both body sides, while in standing position the risk was low. Conclusion: Dentists are exposed to ergonomic risk. By combining both sitting and standing position the risk can be reduced.
PB  - Udruženje stomatologa Balkana
T2  - Balkan Journal of Dental Medicine
T1  - Evaluation of ergonomic risks during dental work
VL  - 20
IS  - 1
SP  - 33
EP  - 39
DO  - 10.1515/bjdm-2016-0005
ER  - 

@article{
author = "Petrović, Vanja and Pejčić, Nataša and Bulat, Petar and Đurić-Jovičić, Milica and Miljković, Nadica and Marković, Dejan",
year = "2016",
abstract = "Aim: The purpose was to assess ergonomic risk level in dentistry, which may contribute to manifestation of musculoskeletal disorders (MSD). Methods and Materials: The study included ten dentists, postgraduate students, mean age (33 ± 3.4). Participants were asked to perform typical dental examination in standing and sitting positions. The surface electromyography (EMG) was recorded during dental work from both left and right shoulder muscles: descendent trapezius muscle (T); back muscles: erector spinae muscle (ES); and neck muscles: sternocleidomastoid muscle (SCM) and splenius capitis muscle (SC). Results: High muscles forces, greater than 21% of the maximal voluntary contraction (MVC), which could be indicative of high risk, particularly occurred in muscles SC on both sides of the body in the sitting position. The medium risk level occurred in the same muscles on both sides in standing position. Left and right T muscles were under medium ergonomic risk level in both, sitting and standing working positions. SCM muscles on the left and right side of the body in both working positions were under low risk level, lower than 10% of the MVC. In sitting position, medium risk level occurred in ES muscles on both body sides, while in standing position the risk was low. Conclusion: Dentists are exposed to ergonomic risk. By combining both sitting and standing position the risk can be reduced.",
publisher = "Udruženje stomatologa Balkana",
journal = "Balkan Journal of Dental Medicine",
title = "Evaluation of ergonomic risks during dental work",
volume = "20",
number = "1",
pages = "33-39",
doi = "10.1515/bjdm-2016-0005"
}

Petrović, V., Pejčić, N., Bulat, P., Đurić-Jovičić, M., Miljković, N.,& Marković, D.. (2016). Evaluation of ergonomic risks during dental work. in Balkan Journal of Dental Medicine
Udruženje stomatologa Balkana., 20(1), 33-39.
https://doi.org/10.1515/bjdm-2016-0005

Petrović V, Pejčić N, Bulat P, Đurić-Jovičić M, Miljković N, Marković D. Evaluation of ergonomic risks during dental work. in Balkan Journal of Dental Medicine. 2016;20(1):33-39.
doi:10.1515/bjdm-2016-0005 .

Petrović, Vanja, Pejčić, Nataša, Bulat, Petar, Đurić-Jovičić, Milica, Miljković, Nadica, Marković, Dejan, "Evaluation of ergonomic risks during dental work" in Balkan Journal of Dental Medicine, 20, no. 1 (2016):33-39,
https://doi.org/10.1515/bjdm-2016-0005 . .

TY  - JOUR
AU  - Pejčić, Nataša
AU  - Đurić-Jovičić, Milica
AU  - Miljković, Nadica
AU  - Popović, Dejan B.
AU  - Petrović, Vanja
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2160
AB  - Introduction Adequate working posture is important for overall health. Inappropriate posture may increase fatigue, decrease efficiency, and eventually lead to injuries. Objective The purpose was to examine posture positions used during dentistry work. Methods In order to quantify different posture positions, we recorded muscle activity and positions of body segments. The position (inclination) data of the back was used to assess two postures: sitting and standing during standard dental interventions. Results During standard interventions, whether sitting or standing, a tilt of less than 20 degrees was most prevalent in the forward and lateral flexion directions. Amplitude of electromyography signals corresponding to the level of muscle activity were higher in sitting compared with the electromyography in standing position for all muscle groups on the left and right side of the body. Significant difference between muscle activity in two working postures was evident in splenius capitis muscle on the left (p = 0.032), on the right side of the body (p = 0.049) and in muscle activity of mastoid muscle on the left side (p = 0.029). Conclusion These findings show that risk for increased fatigue and possible injures can be reduced by combining the sitting and standing occupational postures.
AB  - Uvod Neadekvatan radni položaj tokom rada stomatologa dovodi do povećanog zamora, smanjuje efikasnost i jedan je od vodećih faktora za razvoj povreda na radu među stomatolozima. Ciljevi rada Cilj rada je bio ispitati različite položaje stomatologa tokom kliničkog rada i dati preporuke za poboljšanje radne pozicije. Metode rada Površinskom elektromiografijom (EMG) registrovana je mišićna aktivnost, kao i stepen nagiba tela tokom uobičajnog stomatološkog rada prilikom rada na terapeutskoj stolici i u stajaćem položaju. Rezultati Nagib manji od 20 stepeni bio je izmeren tokom većeg dela kliničkog rada stomatologa u obe radne pozicije. Povećanje mišićne aktivnosti uočeno je prilikom rada u sedećem položaju kod svih ispitivanih mišića. Statistički značajna razlika uočena je kod M. splenius capitisa sa leve (p = 0,032) i sa desne strane (p = 0,049), dok je kod M. sternocleidomastoideusa postojala samo na levoj strani tela (p = 0,029). Zaključak Da bi se smanjio zamor i rizik za nastanak mišićno-skeletnih oboljenja, preporučuje se da stomatolozi tokom kliničkog rada kombinuju sedeći i stajaći radni položaj.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Posture in dentists: Sitting vs. standing positions during dentistry work: An EMG study
T1  - Elektromiografska studija posturalnog položaja tela tokom rada kod stomatologa - poređenje sedećeg i stajaćeg položaja tokom stomatološkog rada
VL  - 144
IS  - 3-4
SP  - 181
EP  - 187
DO  - 10.2298/sarh1604181P
ER  - 

@article{
author = "Pejčić, Nataša and Đurić-Jovičić, Milica and Miljković, Nadica and Popović, Dejan B. and Petrović, Vanja",
year = "2016",
abstract = "Introduction Adequate working posture is important for overall health. Inappropriate posture may increase fatigue, decrease efficiency, and eventually lead to injuries. Objective The purpose was to examine posture positions used during dentistry work. Methods In order to quantify different posture positions, we recorded muscle activity and positions of body segments. The position (inclination) data of the back was used to assess two postures: sitting and standing during standard dental interventions. Results During standard interventions, whether sitting or standing, a tilt of less than 20 degrees was most prevalent in the forward and lateral flexion directions. Amplitude of electromyography signals corresponding to the level of muscle activity were higher in sitting compared with the electromyography in standing position for all muscle groups on the left and right side of the body. Significant difference between muscle activity in two working postures was evident in splenius capitis muscle on the left (p = 0.032), on the right side of the body (p = 0.049) and in muscle activity of mastoid muscle on the left side (p = 0.029). Conclusion These findings show that risk for increased fatigue and possible injures can be reduced by combining the sitting and standing occupational postures., Uvod Neadekvatan radni položaj tokom rada stomatologa dovodi do povećanog zamora, smanjuje efikasnost i jedan je od vodećih faktora za razvoj povreda na radu među stomatolozima. Ciljevi rada Cilj rada je bio ispitati različite položaje stomatologa tokom kliničkog rada i dati preporuke za poboljšanje radne pozicije. Metode rada Površinskom elektromiografijom (EMG) registrovana je mišićna aktivnost, kao i stepen nagiba tela tokom uobičajnog stomatološkog rada prilikom rada na terapeutskoj stolici i u stajaćem položaju. Rezultati Nagib manji od 20 stepeni bio je izmeren tokom većeg dela kliničkog rada stomatologa u obe radne pozicije. Povećanje mišićne aktivnosti uočeno je prilikom rada u sedećem položaju kod svih ispitivanih mišića. Statistički značajna razlika uočena je kod M. splenius capitisa sa leve (p = 0,032) i sa desne strane (p = 0,049), dok je kod M. sternocleidomastoideusa postojala samo na levoj strani tela (p = 0,029). Zaključak Da bi se smanjio zamor i rizik za nastanak mišićno-skeletnih oboljenja, preporučuje se da stomatolozi tokom kliničkog rada kombinuju sedeći i stajaći radni položaj.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Posture in dentists: Sitting vs. standing positions during dentistry work: An EMG study, Elektromiografska studija posturalnog položaja tela tokom rada kod stomatologa - poređenje sedećeg i stajaćeg položaja tokom stomatološkog rada",
volume = "144",
number = "3-4",
pages = "181-187",
doi = "10.2298/sarh1604181P"
}

Pejčić, N., Đurić-Jovičić, M., Miljković, N., Popović, D. B.,& Petrović, V.. (2016). Posture in dentists: Sitting vs. standing positions during dentistry work: An EMG study. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 144(3-4), 181-187.
https://doi.org/10.2298/sarh1604181P

Pejčić N, Đurić-Jovičić M, Miljković N, Popović DB, Petrović V. Posture in dentists: Sitting vs. standing positions during dentistry work: An EMG study. in Srpski arhiv za celokupno lekarstvo. 2016;144(3-4):181-187.
doi:10.2298/sarh1604181P .

Pejčić, Nataša, Đurić-Jovičić, Milica, Miljković, Nadica, Popović, Dejan B., Petrović, Vanja, "Posture in dentists: Sitting vs. standing positions during dentistry work: An EMG study" in Srpski arhiv za celokupno lekarstvo, 144, no. 3-4 (2016):181-187,
https://doi.org/10.2298/sarh1604181P . .

TY  - JOUR
AU  - Lečić, Jelena
AU  - Čakić, Saša
AU  - Janjic-Pavlović, Ognjenka
AU  - Cicmil, Ana
AU  - Vukotić, Olivera
AU  - Petrović, Vanja
AU  - Cicmil, Smiljka
PY  - 2016
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2087
AB  - Objective: The aim of this study was to evaluate clinical efficacy of different chlorhexidine gluconate (CHX) preparations applied subgingivally as an adjunct to scaling and root planing (SRP).Material and methods: A total of 120 periodontal pockets was included in this randomized, controlled, split mouth designed study. According to protocols used in treatment, periodontal pockets were assigned to experimental and control groups as follows: CHX solution as an addition to SRP versus control SRP group; CHX gel as an addition to SRP versus control SRP; CHX chip as an addition to SRP versus control SRP group. Following clinical parameters were recorded at baseline, one and three months after the baseline: plaque index (PI), probing pocket depth (PPD), bleeding index (BI) and clinical attachment level (CAL).Results: The most significant improvements were found concerning PI in CHX solution with SRP and CHX gel with SRP groups over controls at one month recall, as well as concerning BI and PPD in CHX chip with SRP group over SRP alone at three-month recall.Conclusion: Results of this study favour combination therapy using CHX chip as an adjunct to SRP due to greater improvements in BI and PPD compared to those obtained by SRP alone in the treatment of chronic periodontitis.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Acta Odontologica Scandinavica
T1  - Different methods for subgingival application of chlorhexidine in the treatment of patients with chronic periodontitis
VL  - 74
IS  - 6
SP  - 502
EP  - 507
DO  - 10.1080/00016357.2016.1206964
ER  - 

@article{
author = "Lečić, Jelena and Čakić, Saša and Janjic-Pavlović, Ognjenka and Cicmil, Ana and Vukotić, Olivera and Petrović, Vanja and Cicmil, Smiljka",
year = "2016",
abstract = "Objective: The aim of this study was to evaluate clinical efficacy of different chlorhexidine gluconate (CHX) preparations applied subgingivally as an adjunct to scaling and root planing (SRP).Material and methods: A total of 120 periodontal pockets was included in this randomized, controlled, split mouth designed study. According to protocols used in treatment, periodontal pockets were assigned to experimental and control groups as follows: CHX solution as an addition to SRP versus control SRP group; CHX gel as an addition to SRP versus control SRP; CHX chip as an addition to SRP versus control SRP group. Following clinical parameters were recorded at baseline, one and three months after the baseline: plaque index (PI), probing pocket depth (PPD), bleeding index (BI) and clinical attachment level (CAL).Results: The most significant improvements were found concerning PI in CHX solution with SRP and CHX gel with SRP groups over controls at one month recall, as well as concerning BI and PPD in CHX chip with SRP group over SRP alone at three-month recall.Conclusion: Results of this study favour combination therapy using CHX chip as an adjunct to SRP due to greater improvements in BI and PPD compared to those obtained by SRP alone in the treatment of chronic periodontitis.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Acta Odontologica Scandinavica",
title = "Different methods for subgingival application of chlorhexidine in the treatment of patients with chronic periodontitis",
volume = "74",
number = "6",
pages = "502-507",
doi = "10.1080/00016357.2016.1206964"
}

Lečić, J., Čakić, S., Janjic-Pavlović, O., Cicmil, A., Vukotić, O., Petrović, V.,& Cicmil, S.. (2016). Different methods for subgingival application of chlorhexidine in the treatment of patients with chronic periodontitis. in Acta Odontologica Scandinavica
Taylor & Francis Ltd, Abingdon., 74(6), 502-507.
https://doi.org/10.1080/00016357.2016.1206964

Lečić J, Čakić S, Janjic-Pavlović O, Cicmil A, Vukotić O, Petrović V, Cicmil S. Different methods for subgingival application of chlorhexidine in the treatment of patients with chronic periodontitis. in Acta Odontologica Scandinavica. 2016;74(6):502-507.
doi:10.1080/00016357.2016.1206964 .

Lečić, Jelena, Čakić, Saša, Janjic-Pavlović, Ognjenka, Cicmil, Ana, Vukotić, Olivera, Petrović, Vanja, Cicmil, Smiljka, "Different methods for subgingival application of chlorhexidine in the treatment of patients with chronic periodontitis" in Acta Odontologica Scandinavica, 74, no. 6 (2016):502-507,
https://doi.org/10.1080/00016357.2016.1206964 . .

TY  - JOUR
AU  - Marković, Dejan
AU  - Perić, Tamara
AU  - Sovtić, Aleksandar
AU  - Minić, Predrag
AU  - Petrović, Vanja
PY  - 2015
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/2053
AB  - Introduction It has been suggested that asthmatic patients may have a higher risk for oral diseases, both as a result of the medical condition and effects of medications. Objective The aim of the study was to determine the oral health status of children with asthma and to evaluate the oral health parameters according to the medications and severity of the disease. Methods The study group consisted of 158 children with asthma and 100 healthy control subjects aged 2-18 years. The diagnosis of dental caries was performed using the Decayed, Missing, and Filled Teeth (DMFT/dmft) criteria. The oral hygiene, periodontal status and gingival health were assessed with the Simplified Oral Hygiene Index (Greene-Vermillion), Community Periodontal Index of Treatment Needs and Gingival Index (Loe-Silness), respectively. Results Thirty (19%) patients with asthma and 43 (43%) healthy children were caries-free (p lt 0.001). There were no significant differences between asthmatic and control children in caries experience (for children with asthma mean DMFT=2.1±}1.8, mean dmft=4.2±}3.3; for healthy children mean DMFT=2.5±}0.9, mean dmft=5.2±}1.3). Level of asthma control did not have influence on dental health, while dose of inhaled corticosteroid had impact on primary dentition. Periodontal status and gingival health did not differ between asthmatic and control children. However, children with asthma had poorer oral hygiene (p lt 0.001). Conclusion Results of the study do not show a relationship between asthma and oral diseases. However, further improvement could be made in educating children and parents on the importance of good oral hygiene and prevention of oral diseases.
AB  - Uvod Stavovi o oralnom zdravlju dece obolele od astme još nisu usaglašeni, a mogući nepovoljni uticaji lekova koji se koriste u lečenju nisu potpuno definisani. Cilj rada Cilj rada je bio da se utvrdi stanje oralnog zdravlja dece obolele od astme i ispita povezanost primene lekova i stepena kontrole bolesti na pojavu oralnih oboljenja kod ove dece. Metode rada U istraživanje je uključeno 158 dece obolele od astme i 100 zdrave dece uzrasta 2-18 godina kod koje je analizirano stanje oralnog zdravlja. Ispitani su: zastupljenost oboljenja zuba (indeks KEP/kep), stanje gingive (Loe-Silnesov gingivalni indeks), zastupljenost parodontalnih oboljenja (zajednički parodontalni indeks) i nivo oralne higijene (Grin-Vermilionov indeks). Rezultati Tridesetoro dece obolele od astme (19,0%) i 43 zdrave dece (43,0%) imalo je sve zdrave zube (p lt 0,001). Prosečna zastupljenost karijesa kod zdravih ispitanika(prosečna vrednost indeksa KEP bila je 2,5±}0,9, a indeksa kep 5,2±}1,3) i dece obolele od astme (prosečna vrednost indeksa KEP bila je 2,1±}1,8, a indeksa kep 4,2±}3,3) bila je bez značajne razlike. Stepen kontrole astme nije uticao na zdravlje zuba, dok je doza inhalacionih kortikosteroida pokazala uticaj u mlečnoj denticiji. Parodontalni status i zdravlje gingive nisu se razlikovali između dece obolele od astme i zdravih ispitanika. Deca obolela od astme imala su značajno lošiju higijenu usta i zuba (p lt 0,001). Zaključak Rezultati istraživanja ne ukazuju na povezanost astme i oralnih oboljenja kod dece. Loša higijena usta i zuba kod dece obolele od astme ukazuje na potrebu dodatne edukacije i primene posebnih programa prevencije, kako bi se rizici za nastanak ovih oboljenja sveli na najmanju meru.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Oral health in children with asthma
T1  - Stanje oralnog zdravlja kod dece obolele od astme
VL  - 143
IS  - 9-10
SP  - 539
EP  - 544
DO  - 10.2298/SARH1510539M
ER  - 

@article{
author = "Marković, Dejan and Perić, Tamara and Sovtić, Aleksandar and Minić, Predrag and Petrović, Vanja",
year = "2015",
abstract = "Introduction It has been suggested that asthmatic patients may have a higher risk for oral diseases, both as a result of the medical condition and effects of medications. Objective The aim of the study was to determine the oral health status of children with asthma and to evaluate the oral health parameters according to the medications and severity of the disease. Methods The study group consisted of 158 children with asthma and 100 healthy control subjects aged 2-18 years. The diagnosis of dental caries was performed using the Decayed, Missing, and Filled Teeth (DMFT/dmft) criteria. The oral hygiene, periodontal status and gingival health were assessed with the Simplified Oral Hygiene Index (Greene-Vermillion), Community Periodontal Index of Treatment Needs and Gingival Index (Loe-Silness), respectively. Results Thirty (19%) patients with asthma and 43 (43%) healthy children were caries-free (p lt 0.001). There were no significant differences between asthmatic and control children in caries experience (for children with asthma mean DMFT=2.1±}1.8, mean dmft=4.2±}3.3; for healthy children mean DMFT=2.5±}0.9, mean dmft=5.2±}1.3). Level of asthma control did not have influence on dental health, while dose of inhaled corticosteroid had impact on primary dentition. Periodontal status and gingival health did not differ between asthmatic and control children. However, children with asthma had poorer oral hygiene (p lt 0.001). Conclusion Results of the study do not show a relationship between asthma and oral diseases. However, further improvement could be made in educating children and parents on the importance of good oral hygiene and prevention of oral diseases., Uvod Stavovi o oralnom zdravlju dece obolele od astme još nisu usaglašeni, a mogući nepovoljni uticaji lekova koji se koriste u lečenju nisu potpuno definisani. Cilj rada Cilj rada je bio da se utvrdi stanje oralnog zdravlja dece obolele od astme i ispita povezanost primene lekova i stepena kontrole bolesti na pojavu oralnih oboljenja kod ove dece. Metode rada U istraživanje je uključeno 158 dece obolele od astme i 100 zdrave dece uzrasta 2-18 godina kod koje je analizirano stanje oralnog zdravlja. Ispitani su: zastupljenost oboljenja zuba (indeks KEP/kep), stanje gingive (Loe-Silnesov gingivalni indeks), zastupljenost parodontalnih oboljenja (zajednički parodontalni indeks) i nivo oralne higijene (Grin-Vermilionov indeks). Rezultati Tridesetoro dece obolele od astme (19,0%) i 43 zdrave dece (43,0%) imalo je sve zdrave zube (p lt 0,001). Prosečna zastupljenost karijesa kod zdravih ispitanika(prosečna vrednost indeksa KEP bila je 2,5±}0,9, a indeksa kep 5,2±}1,3) i dece obolele od astme (prosečna vrednost indeksa KEP bila je 2,1±}1,8, a indeksa kep 4,2±}3,3) bila je bez značajne razlike. Stepen kontrole astme nije uticao na zdravlje zuba, dok je doza inhalacionih kortikosteroida pokazala uticaj u mlečnoj denticiji. Parodontalni status i zdravlje gingive nisu se razlikovali između dece obolele od astme i zdravih ispitanika. Deca obolela od astme imala su značajno lošiju higijenu usta i zuba (p lt 0,001). Zaključak Rezultati istraživanja ne ukazuju na povezanost astme i oralnih oboljenja kod dece. Loša higijena usta i zuba kod dece obolele od astme ukazuje na potrebu dodatne edukacije i primene posebnih programa prevencije, kako bi se rizici za nastanak ovih oboljenja sveli na najmanju meru.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Oral health in children with asthma, Stanje oralnog zdravlja kod dece obolele od astme",
volume = "143",
number = "9-10",
pages = "539-544",
doi = "10.2298/SARH1510539M"
}

Marković, D., Perić, T., Sovtić, A., Minić, P.,& Petrović, V.. (2015). Oral health in children with asthma. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 143(9-10), 539-544.
https://doi.org/10.2298/SARH1510539M

Marković D, Perić T, Sovtić A, Minić P, Petrović V. Oral health in children with asthma. in Srpski arhiv za celokupno lekarstvo. 2015;143(9-10):539-544.
doi:10.2298/SARH1510539M .

Marković, Dejan, Perić, Tamara, Sovtić, Aleksandar, Minić, Predrag, Petrović, Vanja, "Oral health in children with asthma" in Srpski arhiv za celokupno lekarstvo, 143, no. 9-10 (2015):539-544,
https://doi.org/10.2298/SARH1510539M . .

TY  - JOUR
AU  - Petrović, Vanja
AU  - Pejčić, Nataša
AU  - Čakić, Saša
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1823
AB  - Background. Traumatic injuries of permanent teeth with incomplete root formation are frequent during childhood. Adequate therapy is important for the further destiny of teeth with damaged pulp. Objectives. To evaluate the effect of pulpotomy and high pulpotomy on the pulp and on root development, and the effect of platelet rich plasma (PRP) with hydroxyapatite (HAP) as a carrier and hydroxyapatite alone on apexogenesis. Material and Methods. The study included eight monkeys (Cercopithecus aethiops) in which high pulpotomies were performed on the mandibular lateral incisors and canines, and pulpotomies were performed on the mandibular central incisors and premolars. The materials used in the study were commercial HAP (Apatec (R), Stomygen) and PR? (prepared at the Torlak Institute of Immunology and Virology, Belgrade, Serbia). Histological and radiological evaluations were done six months after the treatment. Results. Considering the differences between HAP+PRP treated teeth in the pulpotomy group and teeth in the high pulpotomy group, two times more root growth retardation was observed in the high pulpotomy group. In the high pulpotomy group, root growth retardation was less common in HAP+PRP treated teeth (42.9%) than in HAP treated teeth (50%). In the pulpotomy group, retardation of root development was also less common in HAP+PRP treated teeth (25%) compared to HAP treated teeth (50%). There were differences between the pulpotomy and high pulpotomy groups, but without statistical significance. Conclusions. The application of endogenous growth factors in conjunction with the preservation of dental pulp vitality can result in a good outcome for pulp therapy of injured teeth, which means successfully completed apexogenesis
T2  - Advances in Clinical & Experimental Medicine
T1  - The Influence of Different Therapeutic Modalities and Platelet Rich Plasma on Apexogenesis - a Preliminary Study in Monkeys
VL  - 22
IS  - 4
SP  - 469
EP  - 479
UR  - https://hdl.handle.net/21.15107/rcub_smile_1823
ER  - 

@article{
author = "Petrović, Vanja and Pejčić, Nataša and Čakić, Saša",
year = "2013",
abstract = "Background. Traumatic injuries of permanent teeth with incomplete root formation are frequent during childhood. Adequate therapy is important for the further destiny of teeth with damaged pulp. Objectives. To evaluate the effect of pulpotomy and high pulpotomy on the pulp and on root development, and the effect of platelet rich plasma (PRP) with hydroxyapatite (HAP) as a carrier and hydroxyapatite alone on apexogenesis. Material and Methods. The study included eight monkeys (Cercopithecus aethiops) in which high pulpotomies were performed on the mandibular lateral incisors and canines, and pulpotomies were performed on the mandibular central incisors and premolars. The materials used in the study were commercial HAP (Apatec (R), Stomygen) and PR? (prepared at the Torlak Institute of Immunology and Virology, Belgrade, Serbia). Histological and radiological evaluations were done six months after the treatment. Results. Considering the differences between HAP+PRP treated teeth in the pulpotomy group and teeth in the high pulpotomy group, two times more root growth retardation was observed in the high pulpotomy group. In the high pulpotomy group, root growth retardation was less common in HAP+PRP treated teeth (42.9%) than in HAP treated teeth (50%). In the pulpotomy group, retardation of root development was also less common in HAP+PRP treated teeth (25%) compared to HAP treated teeth (50%). There were differences between the pulpotomy and high pulpotomy groups, but without statistical significance. Conclusions. The application of endogenous growth factors in conjunction with the preservation of dental pulp vitality can result in a good outcome for pulp therapy of injured teeth, which means successfully completed apexogenesis",
journal = "Advances in Clinical & Experimental Medicine",
title = "The Influence of Different Therapeutic Modalities and Platelet Rich Plasma on Apexogenesis - a Preliminary Study in Monkeys",
volume = "22",
number = "4",
pages = "469-479",
url = "https://hdl.handle.net/21.15107/rcub_smile_1823"
}

Petrović, V., Pejčić, N.,& Čakić, S.. (2013). The Influence of Different Therapeutic Modalities and Platelet Rich Plasma on Apexogenesis - a Preliminary Study in Monkeys. in Advances in Clinical & Experimental Medicine, 22(4), 469-479.
https://hdl.handle.net/21.15107/rcub_smile_1823

Petrović V, Pejčić N, Čakić S. The Influence of Different Therapeutic Modalities and Platelet Rich Plasma on Apexogenesis - a Preliminary Study in Monkeys. in Advances in Clinical & Experimental Medicine. 2013;22(4):469-479.
https://hdl.handle.net/21.15107/rcub_smile_1823 .

Petrović, Vanja, Pejčić, Nataša, Čakić, Saša, "The Influence of Different Therapeutic Modalities and Platelet Rich Plasma on Apexogenesis - a Preliminary Study in Monkeys" in Advances in Clinical & Experimental Medicine, 22, no. 4 (2013):469-479,
https://hdl.handle.net/21.15107/rcub_smile_1823 .

TY  - JOUR
AU  - Novaković, Nada
AU  - Čakić, Saša
AU  - Todorović, Tatjana
AU  - Anđelski-Radičević, Biljana
AU  - Dožić, Ivan
AU  - Petrović, Vanja
AU  - Perunović, Neda
AU  - Špadijer-Gostović, Aleksandra
AU  - Kadović-Sretenović, Jana
AU  - Čolak, Emina
PY  - 2013
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1796
AB  - Introduction. Oxidative stress and antioxidants play an important role in the pathogenesis of inflammatory disease, including chronic periodontitis (CP). Saliva contains enzymatic (glutathione peroxidase - GPx, superoxide dismutase - SOD, etc.) and non-enzymatic (albumin - ALB, uric acid - UA, glutathione, etc.) antioxidants. Objective. The aims of this study were to investigate: a) level of SOD, GPx, UA, ALB and total antioxidative status (TAS) of saliva in CP patients before and after non-surgical treatment, and b) correlations between clinical periodontal parameters and levels of salivary antioxidants. Methods. Saliva was collected from 21 CP patients before and after non-surgical treatment. The condition of periodontium was assessed by plaque index, gingival index, bleeding on probing, probing depth and clinical attachment loss. Level of investigated antioxidants (except GPx) and TAS was determined using colorimetric method and commercial kits. GPx activity was determined using UV method and commercial kits. Results. After the treatment significant increase of UA, ALB, Gpx, TAS was detected (p lt 0.01) and decrease of SOD activity (p>0.05). A significant correlation was observed between GPx and PI (r=0.575, p=0.008), SOD and GI (r=0.525, p=0.017) before therapy, and SOD and bleeding on probing (BP) (r=0.59, p=0.006), TAS and BP (r=0.453, p=0.045) after therapy. Conclusion. These data suggest that levels of salivary antioxidants generally increase after non-surgical periodontal treatment. Correlation between some clinical periodontal parameters and level of salivary antioxidants was found.
AB  - Uvod. Oksidativni stres i antioksidansi igraju važnu ulogu u patogenezi zapaljenjskih oboljenja, uključujući i hroničnu parodontopatiju. Pljuvačka sadrži enzimske antioksidanse, kao što su glutation-peroksidaza (GPx) i superoksid-dismutaza (SOD), i neenzimske antioksidanse, poput albumina (ALB), mokraćne kiseline (UA), glutationa itd. Cilj rada. Cilj istraživanja bio je da se ispitaju nivoi SOD, GPx, UA i ALB i utvrdi ukupan antioksidantni status pljuvačke (TAS) kod osoba s hroničnom parodontopatijom pre i posle kauzalne terapije, te ustanove korelacije između kliničkih pokazatelja stanja parodoncijuma i nivoa antioksidansa u pljuvački. Metode rada. Pljuvačka je sakupljena od 21 pacijenta s hroničnom parodontopatijom pre i posle kauzalne terapije. Stanje parodoncijuma je procenjivano pomoću: plak-indeksa (PI), gingivalnog indeksa (GI), indeksa krvarenja gingive (BP), dubine parodontalnog džepa i nivoa pripojnog epitela. Nivo ispitivanih antioksidansa (osim GPx) i TAS određivan je pomoću kolorimetrijske metode i komercijalnih reagensa. GPx je određivan primenom UV metode i komercijalnih reagensa. Rezultati. Nakon terapije ustanovljeni su značajno povećanje koncentracije UA, GPx i TAS (p lt 0,01) i smanjenje aktivnosti SOD (p>0,05). Primećena je i značajna korelacija između GPx i PI (r=0,575; p=0,008), te SOD i GI (r=0,525; p=0,017) pre terapije, odnosno SOD i BP (r=0,59; p=0,006), kao i TAS i BP (r=0,453; p=0,045) posle nje. Zaključak. Dobijeni nalazi pokazuju da se nivoi antioksidansa u pljuvački povećavaju nakon kauzalne terapije parodontopatije. Uočene su pozitivne korelacije između kliničkih pokazatelja stanja parodoncijuma i ispitivanih koncentracija antioksidansa u pljuvački.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Antioxidative status of saliva before and after non-surgical periodontal treatment
T1  - Antioksidantni status pljuvačke pre i posle kauzalne terapije parodontopatije
VL  - 141
IS  - 3-4
SP  - 163
EP  - 168
DO  - 10.2298/SARH1304163N
ER  - 

@article{
author = "Novaković, Nada and Čakić, Saša and Todorović, Tatjana and Anđelski-Radičević, Biljana and Dožić, Ivan and Petrović, Vanja and Perunović, Neda and Špadijer-Gostović, Aleksandra and Kadović-Sretenović, Jana and Čolak, Emina",
year = "2013",
abstract = "Introduction. Oxidative stress and antioxidants play an important role in the pathogenesis of inflammatory disease, including chronic periodontitis (CP). Saliva contains enzymatic (glutathione peroxidase - GPx, superoxide dismutase - SOD, etc.) and non-enzymatic (albumin - ALB, uric acid - UA, glutathione, etc.) antioxidants. Objective. The aims of this study were to investigate: a) level of SOD, GPx, UA, ALB and total antioxidative status (TAS) of saliva in CP patients before and after non-surgical treatment, and b) correlations between clinical periodontal parameters and levels of salivary antioxidants. Methods. Saliva was collected from 21 CP patients before and after non-surgical treatment. The condition of periodontium was assessed by plaque index, gingival index, bleeding on probing, probing depth and clinical attachment loss. Level of investigated antioxidants (except GPx) and TAS was determined using colorimetric method and commercial kits. GPx activity was determined using UV method and commercial kits. Results. After the treatment significant increase of UA, ALB, Gpx, TAS was detected (p lt 0.01) and decrease of SOD activity (p>0.05). A significant correlation was observed between GPx and PI (r=0.575, p=0.008), SOD and GI (r=0.525, p=0.017) before therapy, and SOD and bleeding on probing (BP) (r=0.59, p=0.006), TAS and BP (r=0.453, p=0.045) after therapy. Conclusion. These data suggest that levels of salivary antioxidants generally increase after non-surgical periodontal treatment. Correlation between some clinical periodontal parameters and level of salivary antioxidants was found., Uvod. Oksidativni stres i antioksidansi igraju važnu ulogu u patogenezi zapaljenjskih oboljenja, uključujući i hroničnu parodontopatiju. Pljuvačka sadrži enzimske antioksidanse, kao što su glutation-peroksidaza (GPx) i superoksid-dismutaza (SOD), i neenzimske antioksidanse, poput albumina (ALB), mokraćne kiseline (UA), glutationa itd. Cilj rada. Cilj istraživanja bio je da se ispitaju nivoi SOD, GPx, UA i ALB i utvrdi ukupan antioksidantni status pljuvačke (TAS) kod osoba s hroničnom parodontopatijom pre i posle kauzalne terapije, te ustanove korelacije između kliničkih pokazatelja stanja parodoncijuma i nivoa antioksidansa u pljuvački. Metode rada. Pljuvačka je sakupljena od 21 pacijenta s hroničnom parodontopatijom pre i posle kauzalne terapije. Stanje parodoncijuma je procenjivano pomoću: plak-indeksa (PI), gingivalnog indeksa (GI), indeksa krvarenja gingive (BP), dubine parodontalnog džepa i nivoa pripojnog epitela. Nivo ispitivanih antioksidansa (osim GPx) i TAS određivan je pomoću kolorimetrijske metode i komercijalnih reagensa. GPx je određivan primenom UV metode i komercijalnih reagensa. Rezultati. Nakon terapije ustanovljeni su značajno povećanje koncentracije UA, GPx i TAS (p lt 0,01) i smanjenje aktivnosti SOD (p>0,05). Primećena je i značajna korelacija između GPx i PI (r=0,575; p=0,008), te SOD i GI (r=0,525; p=0,017) pre terapije, odnosno SOD i BP (r=0,59; p=0,006), kao i TAS i BP (r=0,453; p=0,045) posle nje. Zaključak. Dobijeni nalazi pokazuju da se nivoi antioksidansa u pljuvački povećavaju nakon kauzalne terapije parodontopatije. Uočene su pozitivne korelacije između kliničkih pokazatelja stanja parodoncijuma i ispitivanih koncentracija antioksidansa u pljuvački.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Antioxidative status of saliva before and after non-surgical periodontal treatment, Antioksidantni status pljuvačke pre i posle kauzalne terapije parodontopatije",
volume = "141",
number = "3-4",
pages = "163-168",
doi = "10.2298/SARH1304163N"
}

Novaković, N., Čakić, S., Todorović, T., Anđelski-Radičević, B., Dožić, I., Petrović, V., Perunović, N., Špadijer-Gostović, A., Kadović-Sretenović, J.,& Čolak, E.. (2013). Antioxidative status of saliva before and after non-surgical periodontal treatment. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 141(3-4), 163-168.
https://doi.org/10.2298/SARH1304163N

Novaković N, Čakić S, Todorović T, Anđelski-Radičević B, Dožić I, Petrović V, Perunović N, Špadijer-Gostović A, Kadović-Sretenović J, Čolak E. Antioxidative status of saliva before and after non-surgical periodontal treatment. in Srpski arhiv za celokupno lekarstvo. 2013;141(3-4):163-168.
doi:10.2298/SARH1304163N .

Novaković, Nada, Čakić, Saša, Todorović, Tatjana, Anđelski-Radičević, Biljana, Dožić, Ivan, Petrović, Vanja, Perunović, Neda, Špadijer-Gostović, Aleksandra, Kadović-Sretenović, Jana, Čolak, Emina, "Antioxidative status of saliva before and after non-surgical periodontal treatment" in Srpski arhiv za celokupno lekarstvo, 141, no. 3-4 (2013):163-168,
https://doi.org/10.2298/SARH1304163N . .

TY  - JOUR
AU  - Petrović, Vanja
AU  - Pejčić, Nataša
AU  - Rakić, Mia
AU  - Leković, Vojislav
AU  - Vasić, Una
AU  - Stojić, Ž.
PY  - 2012
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1707
AB  - Platelet-reach plasma (PRP) is an attractive tool in regenerative medicine due to its ability to stimulate proliferation and differentiation of stem cells. Since dental pulp derived stem cells are recognized as central in apexogenesis, the aim of the study was to evaluate radiologically and histologically effects of PRP on apexogenesis in teeth with immature roots. The study included eight monkeys (Cercopithecus Aethiops) divided in two equal groups for evaluation 3 and 12 months after treatment. All participants obtained the same treatment including pulpotomy and after-treatment with: hydroxiapatite (HA)-incisor and HA+canine PRP. Radiological evaluation was performed using the long cone paralleling technique for recording of defined parameters and histological evaluation was performed using tissue removed en block for the observation of parameters related to apexogenesis. The results obtained radiologically and histologically have shown increase in bridge formation in HA+PRP (75%) group after 3 months comparing to HA group (50%). Contrary to that, after 12 months there were no significant differences between groups. The root delay was not registered in the HA+PRP group contrary to HA group where it was registered in 25% after 12 months. Results of the study suggest that PRP is a powerful tool for intensive and rapid apexogenesis since it offers clear and comprehensive results (mostly in the first three months) which are early radiologically visible without any failure in the proposed requests.
AB  - Primena plazme bogate trombocitima (PRP) predstavlja atraktivnu metodu u savremenoj regenerativnoj medicini zbog toga što ona ima sposobnost da stimuliš e proliferaciju i diferencijaciju stem ćelija. Kako su stem ćelije poreklom od dentalne pulpe definisane kao glavne u procesu apeksogeneze, cilj ove studije je bio da radiološki i histološki evaluira efekat PRP na apeksogenezu zuba sa nedovrš enim rastom korena. Studija je obuhvatila 8 majmuna (Cercopithecus Aethiops) koji su bili podeljeni u dve jednake grupe za evaluiranje, 3 i 12 meseci nakon terapije. Sve životinje su bile podvrgnute istom tretmanu uključujući pulpotomiju i tretman: hidroksiapatitom (HA) - sekutići i HA+PRP - očnjaci. Radiološka evaluacija je urađena određivanjem zadatih parametara na radiogramima dobijenim paralelnom tehnikom dugog konusa, a histološka analiza je sprovedena analiziranjem parametara svojstvenih apeksogenezi u preparatima uzetim 'en blok' tehnikom. Dobijeni rezultati su radiološki i histološki za dentinski most posle 3 meseca ukazali na porast u grupi HA+PRP (75%) u poređenju sa HA grupom (50%). Nasuprot tome, posle 12 meseci nije bilo razlike među grupama. Zaostatak u razvoju korena nije utvrđen u HA+PRP grupi za razliku od HA grupe gde je utvrđen zaostatak u 25% slučajeva. Rezultati studije navode na zaključak da je PRP moćno sredstvo za brzu i intezivnu apeksogenezu zbog toga što daje jasne i sveobuhvatne rezultate (najviše u prva tri meseca), koji su radiološki rano vidljivi.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - Effects of the platelet rich plasma on apexogenesis in young monkeys: Radiological and hystologycal evaluation
T1  - Efekti plazme bogate trombocitima na apeksogenezu kod mladih majmuna - radiološka i histološka evaluacija
VL  - 62
IS  - 1
SP  - 39
EP  - 52
DO  - 10.2298/AVB1201039P
ER  - 

@article{
author = "Petrović, Vanja and Pejčić, Nataša and Rakić, Mia and Leković, Vojislav and Vasić, Una and Stojić, Ž.",
year = "2012",
abstract = "Platelet-reach plasma (PRP) is an attractive tool in regenerative medicine due to its ability to stimulate proliferation and differentiation of stem cells. Since dental pulp derived stem cells are recognized as central in apexogenesis, the aim of the study was to evaluate radiologically and histologically effects of PRP on apexogenesis in teeth with immature roots. The study included eight monkeys (Cercopithecus Aethiops) divided in two equal groups for evaluation 3 and 12 months after treatment. All participants obtained the same treatment including pulpotomy and after-treatment with: hydroxiapatite (HA)-incisor and HA+canine PRP. Radiological evaluation was performed using the long cone paralleling technique for recording of defined parameters and histological evaluation was performed using tissue removed en block for the observation of parameters related to apexogenesis. The results obtained radiologically and histologically have shown increase in bridge formation in HA+PRP (75%) group after 3 months comparing to HA group (50%). Contrary to that, after 12 months there were no significant differences between groups. The root delay was not registered in the HA+PRP group contrary to HA group where it was registered in 25% after 12 months. Results of the study suggest that PRP is a powerful tool for intensive and rapid apexogenesis since it offers clear and comprehensive results (mostly in the first three months) which are early radiologically visible without any failure in the proposed requests., Primena plazme bogate trombocitima (PRP) predstavlja atraktivnu metodu u savremenoj regenerativnoj medicini zbog toga što ona ima sposobnost da stimuliš e proliferaciju i diferencijaciju stem ćelija. Kako su stem ćelije poreklom od dentalne pulpe definisane kao glavne u procesu apeksogeneze, cilj ove studije je bio da radiološki i histološki evaluira efekat PRP na apeksogenezu zuba sa nedovrš enim rastom korena. Studija je obuhvatila 8 majmuna (Cercopithecus Aethiops) koji su bili podeljeni u dve jednake grupe za evaluiranje, 3 i 12 meseci nakon terapije. Sve životinje su bile podvrgnute istom tretmanu uključujući pulpotomiju i tretman: hidroksiapatitom (HA) - sekutići i HA+PRP - očnjaci. Radiološka evaluacija je urađena određivanjem zadatih parametara na radiogramima dobijenim paralelnom tehnikom dugog konusa, a histološka analiza je sprovedena analiziranjem parametara svojstvenih apeksogenezi u preparatima uzetim 'en blok' tehnikom. Dobijeni rezultati su radiološki i histološki za dentinski most posle 3 meseca ukazali na porast u grupi HA+PRP (75%) u poređenju sa HA grupom (50%). Nasuprot tome, posle 12 meseci nije bilo razlike među grupama. Zaostatak u razvoju korena nije utvrđen u HA+PRP grupi za razliku od HA grupe gde je utvrđen zaostatak u 25% slučajeva. Rezultati studije navode na zaključak da je PRP moćno sredstvo za brzu i intezivnu apeksogenezu zbog toga što daje jasne i sveobuhvatne rezultate (najviše u prva tri meseca), koji su radiološki rano vidljivi.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "Effects of the platelet rich plasma on apexogenesis in young monkeys: Radiological and hystologycal evaluation, Efekti plazme bogate trombocitima na apeksogenezu kod mladih majmuna - radiološka i histološka evaluacija",
volume = "62",
number = "1",
pages = "39-52",
doi = "10.2298/AVB1201039P"
}

Petrović, V., Pejčić, N., Rakić, M., Leković, V., Vasić, U.,& Stojić, Ž.. (2012). Effects of the platelet rich plasma on apexogenesis in young monkeys: Radiological and hystologycal evaluation. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 62(1), 39-52.
https://doi.org/10.2298/AVB1201039P

Petrović V, Pejčić N, Rakić M, Leković V, Vasić U, Stojić Ž. Effects of the platelet rich plasma on apexogenesis in young monkeys: Radiological and hystologycal evaluation. in Acta veterinaria. 2012;62(1):39-52.
doi:10.2298/AVB1201039P .

Petrović, Vanja, Pejčić, Nataša, Rakić, Mia, Leković, Vojislav, Vasić, Una, Stojić, Ž., "Effects of the platelet rich plasma on apexogenesis in young monkeys: Radiological and hystologycal evaluation" in Acta veterinaria, 62, no. 1 (2012):39-52,
https://doi.org/10.2298/AVB1201039P . .

TY  - JOUR
AU  - Petrović, Vanja
AU  - Danilović, Vesna
AU  - Marković, Dejan
AU  - Čakić, Saša
AU  - Krstić, N.
AU  - Marković, Danica
PY  - 2009
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1479
AB  - There are very few data about the effects of endogenous growth factors in vital pulp therapy, and still they are often controversial. This study was undertaken with the aim to evaluate the effects of platelet rich plasma (PRP) in conjugation with hydroxyapatite (HAP), as pulp capping materials, on root and periodontium formation. Eight young monkeys (Cercopithecus Aethiops) with permanent dentition and incomplete root formation were involved in this study. After pulpotomy, the pulp lesion was capped with calcium hydroxide (control), HAP (experimental) or HAP in conjugation with PRP (experimental). Six moths later, the animals were sacrificed, the tissue was removed en block, and prepared for histological analysis in a routine way. The results of histological analysis revealed that the healing process, characterized by dentin bridge formation, maintained morphological and functional integrity of dental pulp and complete formation of dental root and surrounding periodontium. The inflammatory reaction was scored as mild to moderate, in almost all samples in all groups, suggesting the biocompatibility of the used materials. Materials used in this study are convenient as capping agents, contributing in maintaining the integrity of the pulp tissue and facilitating root and periodontium formation. According to histological data it could be suggested that hydroxyapatite in conjugation with endogenous growth factors, represent a superior alternative to other materials used in this study.
AB  - Podaci iz literature o primeni faktora rasta u vitalnoj terapiji pulpe su oskudni i često kontraverzni. Cilj našeg rada je bio da se ispita uticaj plazme bogate trombocitima u kombinaciji sa hidroksiapatitom, kao materijala za direktno prekrivanje pulpe, na završetak rasta korena i formiranje okolnog parodoncijuma. Istraživanje je sprovedeno na osam mladih majmuna (Cercopithecus aethiops), sa stalnom denticijom i nezavršenim rastom korena. Nakon pulpotomije, pulpna lezija je prekrivena kalcijum hidroksidom (kontolna grupa), hidroksiapatitom (eksperimentalna grupa I) ili hidroksiapatitom u kombinaciji sa plazmom bogatom trombocitima (eksperimentalna grupa II). Šest meseci kasnije životinje su žrtvovane, a uzeto tkivo pripremljeno je za histološku analizu. Rezultati histološke analize ukazali su da je zarastanje bilo karakterisano stvaranjem mineralizovanog dentinskog mostića, uz očuvanje morfološkog i funkcionalnog integriteta pulpe i završetak rasta korena i okolnog parodoncijuma u uzorcima svih ispitivanih grupa. Zapaljenska reakcija je gotovo u svim ispitivnim uzorcima bila ocenjena kao blaga ili umerena, što govori u prilog biokompatibilnosti primenjenih materijala. Na osnovu dobijenih rezultata može se reći da su svi primenjeni materijali pogodni za direktno prekrivanje pulpe, da doprinose očuvanju integriteta pulpe i ubrzavaju završetak rasta korena i formiranje apikalnog parodoncijuma, s tim što hidroksipatit u kombinaciji sa endogenim faktorima rasta predstavlja superiorniju alternativu u odnosu na druge materijale korišćene u ovoj studiji.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys
T1  - Uticaj hidroksiapatita i plazme bogate trombocitima na proces apeksogeneze kod majmuna
VL  - 59
IS  - 2-3
SP  - 277
EP  - 289
DO  - 10.2298/AVB0903277P
ER  - 

@article{
author = "Petrović, Vanja and Danilović, Vesna and Marković, Dejan and Čakić, Saša and Krstić, N. and Marković, Danica",
year = "2009",
abstract = "There are very few data about the effects of endogenous growth factors in vital pulp therapy, and still they are often controversial. This study was undertaken with the aim to evaluate the effects of platelet rich plasma (PRP) in conjugation with hydroxyapatite (HAP), as pulp capping materials, on root and periodontium formation. Eight young monkeys (Cercopithecus Aethiops) with permanent dentition and incomplete root formation were involved in this study. After pulpotomy, the pulp lesion was capped with calcium hydroxide (control), HAP (experimental) or HAP in conjugation with PRP (experimental). Six moths later, the animals were sacrificed, the tissue was removed en block, and prepared for histological analysis in a routine way. The results of histological analysis revealed that the healing process, characterized by dentin bridge formation, maintained morphological and functional integrity of dental pulp and complete formation of dental root and surrounding periodontium. The inflammatory reaction was scored as mild to moderate, in almost all samples in all groups, suggesting the biocompatibility of the used materials. Materials used in this study are convenient as capping agents, contributing in maintaining the integrity of the pulp tissue and facilitating root and periodontium formation. According to histological data it could be suggested that hydroxyapatite in conjugation with endogenous growth factors, represent a superior alternative to other materials used in this study., Podaci iz literature o primeni faktora rasta u vitalnoj terapiji pulpe su oskudni i često kontraverzni. Cilj našeg rada je bio da se ispita uticaj plazme bogate trombocitima u kombinaciji sa hidroksiapatitom, kao materijala za direktno prekrivanje pulpe, na završetak rasta korena i formiranje okolnog parodoncijuma. Istraživanje je sprovedeno na osam mladih majmuna (Cercopithecus aethiops), sa stalnom denticijom i nezavršenim rastom korena. Nakon pulpotomije, pulpna lezija je prekrivena kalcijum hidroksidom (kontolna grupa), hidroksiapatitom (eksperimentalna grupa I) ili hidroksiapatitom u kombinaciji sa plazmom bogatom trombocitima (eksperimentalna grupa II). Šest meseci kasnije životinje su žrtvovane, a uzeto tkivo pripremljeno je za histološku analizu. Rezultati histološke analize ukazali su da je zarastanje bilo karakterisano stvaranjem mineralizovanog dentinskog mostića, uz očuvanje morfološkog i funkcionalnog integriteta pulpe i završetak rasta korena i okolnog parodoncijuma u uzorcima svih ispitivanih grupa. Zapaljenska reakcija je gotovo u svim ispitivnim uzorcima bila ocenjena kao blaga ili umerena, što govori u prilog biokompatibilnosti primenjenih materijala. Na osnovu dobijenih rezultata može se reći da su svi primenjeni materijali pogodni za direktno prekrivanje pulpe, da doprinose očuvanju integriteta pulpe i ubrzavaju završetak rasta korena i formiranje apikalnog parodoncijuma, s tim što hidroksipatit u kombinaciji sa endogenim faktorima rasta predstavlja superiorniju alternativu u odnosu na druge materijale korišćene u ovoj studiji.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys, Uticaj hidroksiapatita i plazme bogate trombocitima na proces apeksogeneze kod majmuna",
volume = "59",
number = "2-3",
pages = "277-289",
doi = "10.2298/AVB0903277P"
}

Petrović, V., Danilović, V., Marković, D., Čakić, S., Krstić, N.,& Marković, D.. (2009). The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 59(2-3), 277-289.
https://doi.org/10.2298/AVB0903277P

Petrović V, Danilović V, Marković D, Čakić S, Krstić N, Marković D. The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys. in Acta veterinaria. 2009;59(2-3):277-289.
doi:10.2298/AVB0903277P .

Petrović, Vanja, Danilović, Vesna, Marković, Dejan, Čakić, Saša, Krstić, N., Marković, Danica, "The effects of hydroxyapatite and platelet rich plasma on apexogenesis in monkeys" in Acta veterinaria, 59, no. 2-3 (2009):277-289,
https://doi.org/10.2298/AVB0903277P . .

TY  - JOUR
AU  - Luković, Natalija
AU  - Zelić, Obrad
AU  - Čakić, Saša
AU  - Petrović, Vanja
PY  - 2009
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1461
AB  - Introduction. The primary goal of bone regeneration procedures with application of various regenerative biologic agents and biomaterials is to facilitate the formation of periodontal tissues lost as a result of periodontitis. Objective. The aim of the study was to compare clinical outcome of the guided tissue regeneration (GTR) treatment with the use of β-tricalcium phosphate and with bovine bone matrix in human deep intra-osseous defects. Methods. Twenty-one systemically healthy subjects with moderate to advanced periodontitis, between 30 and 56 years of age, 11 females and 10 males, were selected. Patients having two similar inter-proximal defects with pocket probing depths following initial therapy greater than 5 mm were recruited for the study. Experimental sites were grafted with pure β-tricalcium phosphate biomaterial (Cerasorb®) and a biomembrane, while control sites were treated with bovine-bone hydroxiapatite xenograft (Bio-oss®) and a biomembrane. Immediately before surgery and 12 months after surgery, pocket probing depth (PPD), epithelial attachment level (EAL) and gingival recession (GR) were evaluated. Results. In the experimental group PPD amounted to 6.76±0.83 mm before surgery, and decreased significantly to 2.67±0.48 mm 12 months following surgery, while in the control group PPD significantly decreased from 7.14±0.65 mm presurgically to 2.85±0.57 mm postsurgically. After one year, EAL gain was 2.76±0.99 mm in the experimental group, and 3.24±0.16 mm in the control group. After twelve months postoperatively GR amounted to 1.33±0.79 mm in the experimental group and to 1.05±0.80 mm in the control group. No statistically significant differences for PPD reduction, EAL gain and GR increase were detected between the groups. Conclusion. Results from the present study indicate that GTR treatment of deep intra-osseous defects with Bio-oss® and Cerasorb® resulted in clinically and statistically significant improvement of EAL gain and PPD reduction. A GR was slightly increased, with no statistical significance.
AB  - Uvod. Za regeneraciju tkiva koje je izgubljeno tokom parodontopatije koriste se razni biološki i sintetski materijali s različitim uspehom. Oni se najčešće primenjuju za obnavljanje pripojnog epitela i gubljenje alveolarne kosti u dubokim infrakoštanim oštećenjima. Cilj rada. Cilj rada je bio da se ispita značaj primene beta trikalcijum-fosfata i hidroksiapatita u lečenju dubokih infrakoštanih oštećenja. Metode rada. U istraživanje je uključena dvadeset i jedna zdrava osoba (11 žena i 10 muškaraca) starosti 30-45 godina kod koje je dijagnostikovana parodontopatija. Kod svih ispitanika ustanovljena su dva slična oštećenja sa dubinom sondiranja džepa od preko 5 mm. Tzv. eksperimentalna strana je tretirana čistim beta trikalcijum-fosfatnim biomaterijalom (Cerasorb®) i biomembranom, dok je tzv. kontrolna strana tretirana hidroksiapatitnim goveđim koštanim ksenograftom (Bio-oss®) i biomembranom. Dubina sondiranja džepa, nivo pripojenog epitela i recesija gingive su zabeleženi neposredno pre intervencije i 12 meseci kasnije. Rezultati. U eksperimentalnoj grupi dubina sondiranja džepa je bila 6,76±0,83 mm pre intervencije, a značajno manja nakon 12 meseci (2,76±0,48 mm). U kontrolnoj grupi ona je bila 7,14±0,65 mm pre intervencije, a značajno manja na kontrolnom pregledu (2,85±0,57 mm). Posle godinu dana nivo pripojenog epitela se povećao 2,76±0,99 mm u eksperimentalnoj grupi, odnosno 3,24±0,16 mm u kontrolnoj. Dvanaest meseci nakon intervencije recesija gingive bila je 1,33±0,79 mm u eksperimentalnoj, odnosno 1,05±0,80 mm u kontrolnoj grupi. Nisu zabeležene statistički značajne razlike u vrednosti dubine sondiranja džepa, nivou pripojenog epitela i recesiji gingive između kontrolne i eksperimentalne grupe. Zaključak. Tretman dubokih infrakoštanih oštećenja beta trikalcijum-fosfatom i hidroksiapatitom dao je dobre kliničke rezultate, budući da se značajno smanjila dubina oštećenja, a nivo pripojenog epitela podigao. Recesija gingive se umanjila, ali bez statistički značajne razlike.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - The use of beta-tricalcium phosphate and bovine bone matrix in the guided tissue regeneration treatment of deep infra-bony defects
T1  - Primena beta trikalcijum-fosfata i goveđeg koštanog matriksa u vođenoj regeneraciji dubokih infrakoštanih parodontalnih oštećenja
VL  - 137
IS  - 11-12
SP  - 607
EP  - 612
DO  - 10.2298/SARH0912607L
ER  - 

@article{
author = "Luković, Natalija and Zelić, Obrad and Čakić, Saša and Petrović, Vanja",
year = "2009",
abstract = "Introduction. The primary goal of bone regeneration procedures with application of various regenerative biologic agents and biomaterials is to facilitate the formation of periodontal tissues lost as a result of periodontitis. Objective. The aim of the study was to compare clinical outcome of the guided tissue regeneration (GTR) treatment with the use of β-tricalcium phosphate and with bovine bone matrix in human deep intra-osseous defects. Methods. Twenty-one systemically healthy subjects with moderate to advanced periodontitis, between 30 and 56 years of age, 11 females and 10 males, were selected. Patients having two similar inter-proximal defects with pocket probing depths following initial therapy greater than 5 mm were recruited for the study. Experimental sites were grafted with pure β-tricalcium phosphate biomaterial (Cerasorb®) and a biomembrane, while control sites were treated with bovine-bone hydroxiapatite xenograft (Bio-oss®) and a biomembrane. Immediately before surgery and 12 months after surgery, pocket probing depth (PPD), epithelial attachment level (EAL) and gingival recession (GR) were evaluated. Results. In the experimental group PPD amounted to 6.76±0.83 mm before surgery, and decreased significantly to 2.67±0.48 mm 12 months following surgery, while in the control group PPD significantly decreased from 7.14±0.65 mm presurgically to 2.85±0.57 mm postsurgically. After one year, EAL gain was 2.76±0.99 mm in the experimental group, and 3.24±0.16 mm in the control group. After twelve months postoperatively GR amounted to 1.33±0.79 mm in the experimental group and to 1.05±0.80 mm in the control group. No statistically significant differences for PPD reduction, EAL gain and GR increase were detected between the groups. Conclusion. Results from the present study indicate that GTR treatment of deep intra-osseous defects with Bio-oss® and Cerasorb® resulted in clinically and statistically significant improvement of EAL gain and PPD reduction. A GR was slightly increased, with no statistical significance., Uvod. Za regeneraciju tkiva koje je izgubljeno tokom parodontopatije koriste se razni biološki i sintetski materijali s različitim uspehom. Oni se najčešće primenjuju za obnavljanje pripojnog epitela i gubljenje alveolarne kosti u dubokim infrakoštanim oštećenjima. Cilj rada. Cilj rada je bio da se ispita značaj primene beta trikalcijum-fosfata i hidroksiapatita u lečenju dubokih infrakoštanih oštećenja. Metode rada. U istraživanje je uključena dvadeset i jedna zdrava osoba (11 žena i 10 muškaraca) starosti 30-45 godina kod koje je dijagnostikovana parodontopatija. Kod svih ispitanika ustanovljena su dva slična oštećenja sa dubinom sondiranja džepa od preko 5 mm. Tzv. eksperimentalna strana je tretirana čistim beta trikalcijum-fosfatnim biomaterijalom (Cerasorb®) i biomembranom, dok je tzv. kontrolna strana tretirana hidroksiapatitnim goveđim koštanim ksenograftom (Bio-oss®) i biomembranom. Dubina sondiranja džepa, nivo pripojenog epitela i recesija gingive su zabeleženi neposredno pre intervencije i 12 meseci kasnije. Rezultati. U eksperimentalnoj grupi dubina sondiranja džepa je bila 6,76±0,83 mm pre intervencije, a značajno manja nakon 12 meseci (2,76±0,48 mm). U kontrolnoj grupi ona je bila 7,14±0,65 mm pre intervencije, a značajno manja na kontrolnom pregledu (2,85±0,57 mm). Posle godinu dana nivo pripojenog epitela se povećao 2,76±0,99 mm u eksperimentalnoj grupi, odnosno 3,24±0,16 mm u kontrolnoj. Dvanaest meseci nakon intervencije recesija gingive bila je 1,33±0,79 mm u eksperimentalnoj, odnosno 1,05±0,80 mm u kontrolnoj grupi. Nisu zabeležene statistički značajne razlike u vrednosti dubine sondiranja džepa, nivou pripojenog epitela i recesiji gingive između kontrolne i eksperimentalne grupe. Zaključak. Tretman dubokih infrakoštanih oštećenja beta trikalcijum-fosfatom i hidroksiapatitom dao je dobre kliničke rezultate, budući da se značajno smanjila dubina oštećenja, a nivo pripojenog epitela podigao. Recesija gingive se umanjila, ali bez statistički značajne razlike.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "The use of beta-tricalcium phosphate and bovine bone matrix in the guided tissue regeneration treatment of deep infra-bony defects, Primena beta trikalcijum-fosfata i goveđeg koštanog matriksa u vođenoj regeneraciji dubokih infrakoštanih parodontalnih oštećenja",
volume = "137",
number = "11-12",
pages = "607-612",
doi = "10.2298/SARH0912607L"
}

Luković, N., Zelić, O., Čakić, S.,& Petrović, V.. (2009). The use of beta-tricalcium phosphate and bovine bone matrix in the guided tissue regeneration treatment of deep infra-bony defects. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 137(11-12), 607-612.
https://doi.org/10.2298/SARH0912607L

Luković N, Zelić O, Čakić S, Petrović V. The use of beta-tricalcium phosphate and bovine bone matrix in the guided tissue regeneration treatment of deep infra-bony defects. in Srpski arhiv za celokupno lekarstvo. 2009;137(11-12):607-612.
doi:10.2298/SARH0912607L .

Luković, Natalija, Zelić, Obrad, Čakić, Saša, Petrović, Vanja, "The use of beta-tricalcium phosphate and bovine bone matrix in the guided tissue regeneration treatment of deep infra-bony defects" in Srpski arhiv za celokupno lekarstvo, 137, no. 11-12 (2009):607-612,
https://doi.org/10.2298/SARH0912607L . .

TY  - JOUR
AU  - Danilović, Vesna
AU  - Petrović, Vanja
AU  - Marković, Dejan
AU  - Aleksić, Zoran
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1451
AB  - Background/Aim. There are very few data about the effects of endogenous growth factors in vital pulp therapy, and still they are often controversial. The aim of the study was to evaluate the effects of platelet rich plasma (PRP) in conjugation with hydroxyapatite (HAP), as pulp capping materials, to root and periodontium formation. Methods. Eight young monkeys (Cercopithecus Aethiops) with permanent dentition and incomplete root formation were involved in this study. After pulpotomy, the pulp lesion was capped with calcium hydroxide (control), hydroxyapatite (experimental group I) or hydroxyapatite in conjugation with PRP (experimental group II). Six months later, the animals were sacrificed, the tissue was removed en block, and prepared for the histological analysis in a routine way. Results. The results of the histological analysis revealed that healing process was characterised by dentin bridge formation, maintained morphological and functional integrity of dental pulp and complete formation of dental root and surrounding periodontium. The inflammatory reaction was scored as mild to moderate, in almost all the samples in all groups, suggesting the biocompatibility of the used materials. Conclusion. Materials used in this study are convenient as capping agents, contributing maintaining the integrity of the pulp tissue and facilitating root and periodontium formation. According to histological data it could be suggested that hydroxyapatite in conjugation with endogenous growth factors, represents superior alternative to other materials used in this study.
AB  - Uvod/Cilj. Podaci o primeni endogenih faktora rasta u terapiji vitalne pulpe zuba sa nezavršenim rastom korena su veoma oskudni i često kontraverzni. Cilj ovog rada bio je da se ispita uticaj plazme bogate trombocitima (PRP) u kombinaciji sa hidroksiapatitom (HAP), kao materijala za direktno prekrivanje pulpe, na završetak rasta korena i formiranje okolnog parodoncijuma. Metode. Istraživanje je obavljeno na osam mladih majmuna Cercopithecus Aethiops. Sve životinje imale su zube stalne denticije, sa nezavršenim rastom korena. Nakon trepanacije pulpnog prostora, pulpa je uklonjena do nivoa gleđnocementnog spoja, a lezija u pulpi prekrivena je kalcijum hidroksidom (kontrolna grupa), hidroksiapatitom (eksperimentna grupa I) i hidroksiapatitom u kombinaciji sa autogenim PRP faktorom (eksperimentna grupa II). Šest meseci nakon amputacije pulpe, životinje su žrtvovane, a tkivo za histološku analizu uzeto je u obliku blok sekcije i pripremljeno za mikroskopsku analizu. Rezultati. Zarastanje rane u pulpno-dentinskom kompleksu u obe eksperimentne i u kontrolnoj grupi bilo je karakterisano stvaranjem dentinskog mostića procesom reparativne dentinogeneze, očuvanjem morfološkog i funkcijskog integriteta pulpe, kao i završetkom rasta korena i stvaranjem okolnog parodoncijuma. U većini uzoraka obe grupe, zapaljenska reakcija ocenjena je kao blaga do umerena, što govori u prilog biokompatibilnosti primenjenih materijala. Zaključak. Svi primenjeni materijali pogodni su za direktno prekrivanje pulpe, doprinose očuvanju njenog morfološkog i funkcionalnog integriteta i omogućavaju završetak rasta korena i formiranje okolnog parodoncijuma. Ipak, povoljniji rezultati dobijeni su u grupi koja je tretirana HAP/PRP, pa se može reći da HAP obogaćen endogenim faktorima rasta predstavlja superiorniju alternativu u odnosu na ostale materijale primenjene u ovoj studiji.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Histological evaluation of platelet rich plasma and hydroxiapatite in apexogenesis: Study on experimental animals
T1  - Histološka evaluacija efekata plazme bogate trombocitima i hidroksiapatita u procesu apeksogeneze - studija na eksperimentnim životinjama
VL  - 65
IS  - 2
SP  - 128
EP  - 134
DO  - 10.2298/VSP0802128D
ER  - 

@article{
author = "Danilović, Vesna and Petrović, Vanja and Marković, Dejan and Aleksić, Zoran",
year = "2008",
abstract = "Background/Aim. There are very few data about the effects of endogenous growth factors in vital pulp therapy, and still they are often controversial. The aim of the study was to evaluate the effects of platelet rich plasma (PRP) in conjugation with hydroxyapatite (HAP), as pulp capping materials, to root and periodontium formation. Methods. Eight young monkeys (Cercopithecus Aethiops) with permanent dentition and incomplete root formation were involved in this study. After pulpotomy, the pulp lesion was capped with calcium hydroxide (control), hydroxyapatite (experimental group I) or hydroxyapatite in conjugation with PRP (experimental group II). Six months later, the animals were sacrificed, the tissue was removed en block, and prepared for the histological analysis in a routine way. Results. The results of the histological analysis revealed that healing process was characterised by dentin bridge formation, maintained morphological and functional integrity of dental pulp and complete formation of dental root and surrounding periodontium. The inflammatory reaction was scored as mild to moderate, in almost all the samples in all groups, suggesting the biocompatibility of the used materials. Conclusion. Materials used in this study are convenient as capping agents, contributing maintaining the integrity of the pulp tissue and facilitating root and periodontium formation. According to histological data it could be suggested that hydroxyapatite in conjugation with endogenous growth factors, represents superior alternative to other materials used in this study., Uvod/Cilj. Podaci o primeni endogenih faktora rasta u terapiji vitalne pulpe zuba sa nezavršenim rastom korena su veoma oskudni i često kontraverzni. Cilj ovog rada bio je da se ispita uticaj plazme bogate trombocitima (PRP) u kombinaciji sa hidroksiapatitom (HAP), kao materijala za direktno prekrivanje pulpe, na završetak rasta korena i formiranje okolnog parodoncijuma. Metode. Istraživanje je obavljeno na osam mladih majmuna Cercopithecus Aethiops. Sve životinje imale su zube stalne denticije, sa nezavršenim rastom korena. Nakon trepanacije pulpnog prostora, pulpa je uklonjena do nivoa gleđnocementnog spoja, a lezija u pulpi prekrivena je kalcijum hidroksidom (kontrolna grupa), hidroksiapatitom (eksperimentna grupa I) i hidroksiapatitom u kombinaciji sa autogenim PRP faktorom (eksperimentna grupa II). Šest meseci nakon amputacije pulpe, životinje su žrtvovane, a tkivo za histološku analizu uzeto je u obliku blok sekcije i pripremljeno za mikroskopsku analizu. Rezultati. Zarastanje rane u pulpno-dentinskom kompleksu u obe eksperimentne i u kontrolnoj grupi bilo je karakterisano stvaranjem dentinskog mostića procesom reparativne dentinogeneze, očuvanjem morfološkog i funkcijskog integriteta pulpe, kao i završetkom rasta korena i stvaranjem okolnog parodoncijuma. U većini uzoraka obe grupe, zapaljenska reakcija ocenjena je kao blaga do umerena, što govori u prilog biokompatibilnosti primenjenih materijala. Zaključak. Svi primenjeni materijali pogodni su za direktno prekrivanje pulpe, doprinose očuvanju njenog morfološkog i funkcionalnog integriteta i omogućavaju završetak rasta korena i formiranje okolnog parodoncijuma. Ipak, povoljniji rezultati dobijeni su u grupi koja je tretirana HAP/PRP, pa se može reći da HAP obogaćen endogenim faktorima rasta predstavlja superiorniju alternativu u odnosu na ostale materijale primenjene u ovoj studiji.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Histological evaluation of platelet rich plasma and hydroxiapatite in apexogenesis: Study on experimental animals, Histološka evaluacija efekata plazme bogate trombocitima i hidroksiapatita u procesu apeksogeneze - studija na eksperimentnim životinjama",
volume = "65",
number = "2",
pages = "128-134",
doi = "10.2298/VSP0802128D"
}

Danilović, V., Petrović, V., Marković, D.,& Aleksić, Z.. (2008). Histological evaluation of platelet rich plasma and hydroxiapatite in apexogenesis: Study on experimental animals. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 65(2), 128-134.
https://doi.org/10.2298/VSP0802128D

Danilović V, Petrović V, Marković D, Aleksić Z. Histological evaluation of platelet rich plasma and hydroxiapatite in apexogenesis: Study on experimental animals. in Vojnosanitetski pregled. 2008;65(2):128-134.
doi:10.2298/VSP0802128D .

Danilović, Vesna, Petrović, Vanja, Marković, Dejan, Aleksić, Zoran, "Histological evaluation of platelet rich plasma and hydroxiapatite in apexogenesis: Study on experimental animals" in Vojnosanitetski pregled, 65, no. 2 (2008):128-134,
https://doi.org/10.2298/VSP0802128D . .

TY  - JOUR
AU  - Petrović, Vanja
AU  - Marković, Dejan
AU  - Čakić, Saša
AU  - Krstić, N.
PY  - 2008
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1400
AB  - Management of the affected pulp in teeth with incomplete root formation is still an issue. Calcium hydroxide and other materials have been employed for this purpose to a greater or lesser success. Bioceramic materials are in the last decades well established in a number of different medical fields. Having its constituents the same as those of the unorganic portion of bone tissue, hydroxiapatite (HAP), one of the two forms of calcium-phosphate ceramics, is already accepted in endodontic treatment of teeth with completed root formation. The aim of this study was to examine apexogenesis in teeth with immature roots, following the use of HAP on their affected pulp. Examination was performed on eight young monkeys (Cercopithecus Aethiops) with incomplete root development. The 100 μm synthetic HAP material was applied on 32 teeth divided into two groups of 16 teeth each. In one group teeth underwent pulpotomy, in the other high pulpotomy. Evaluation of root growth was recorded from radiographs (pre-treatment, 3 and 12 months following treatment) and by Demjrian's scale for dental maturity and tooth age determination. On the basis of radiographic analysis, immature teeth with affected pulp treated with HAP, both with pulpotomy and high pulpotomy, reached the same stage of root development as control teeth in 50% of cases at 3-months radiographic assessment. After 12 months all tested teeth had the same rate of root development as control teeth, except for 1 of 8 with high pulpotomy. Dentinal bridge was radiographically visible in 50% and 87.5% of pulpotomized teeth after 3 and 12 months, respectively. Neither obliteration of the root canal, presence of denticles nor the presence of deformities in the periapical region were found in any of the observed teeth.
AB  - Lečenja aficirane pulpe zuba sa nezavršenim rastom korena je još uvek predmet stručnih i naučnih rasprava, između ostalog i zbog neželjenih efekata tradicionalnih preparata na bazi kalcijum hidroksida. Biokeramički materijali se već nekoliko decenija primenjuju u različitim granama medicine, a hidroksiapatit, kao jedna od dve forme kalcijum-fosfatne keramike, ima gotovo istovetan sastav kao neorganski deo kosti, pa je već prihvaćen u endodontskom lečenju zuba sa završ enim rastom korena. Cilj ovog rada je bio da se ispita uticaj hidroksiapatita na apeksogenezu u zuba sa nezavršenim rastom korena i aficiranom pulpom. Ispitivanjem je bilo obuhvaćeno na osam mladih majmuna Cercopithecus Aethiops sa nezavršenim rastom korena zuba. Sintetički hidroksiapatit, veličine čestica od 100 μm je primenjen na trideset dva zuba, podeljenih u dve jednake grupe kod kojih je všena apulpotomija, odnosno visoka pulpotomija. Rendgenološ ka evaluacija rasta korena zuba je vršena pre terapije, kao i tri i dvanaest mesici posle primene HAP, a na osnovu Demjrianove skale za određivanje zrelosti zuba. Na osnovu rendgenološke analize posle 3 meseca je nađeno da je brzina razvoja korena kako pulpotomisanih, tako i visoko pulpotomisanih zuba kod kojih je primenjen HAP bila u 50% slučajeva ista kao kod kontrolnih zuba. Posle 12 meseci stepen razvoja korena zuba je u svih ispitivanih zuba (osim kod jednog od osam zuba sa izvršenom visokom pulpotomijom) bio isti kao u kontrolnih zuba. Dentinski most je bio vidljiv radiološkom analizom u 50% odnosno 87,5% eksperimentalnih zuba posle 3, odnosno posle 12 meseci. Ni u jednom pregledanom zubu rendgenološki nije uočena obliteracija kanala korena, kao ni dentikli ni deformiteti u periapeksnom predelu.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys
T1  - Uticaj hidroksiapatita na apeksogenezu u majmuna - klinička studija
VL  - 58
IS  - 4
SP  - 395
EP  - 409
DO  - 10.2298/AVB0804395P
ER  - 

@article{
author = "Petrović, Vanja and Marković, Dejan and Čakić, Saša and Krstić, N.",
year = "2008",
abstract = "Management of the affected pulp in teeth with incomplete root formation is still an issue. Calcium hydroxide and other materials have been employed for this purpose to a greater or lesser success. Bioceramic materials are in the last decades well established in a number of different medical fields. Having its constituents the same as those of the unorganic portion of bone tissue, hydroxiapatite (HAP), one of the two forms of calcium-phosphate ceramics, is already accepted in endodontic treatment of teeth with completed root formation. The aim of this study was to examine apexogenesis in teeth with immature roots, following the use of HAP on their affected pulp. Examination was performed on eight young monkeys (Cercopithecus Aethiops) with incomplete root development. The 100 μm synthetic HAP material was applied on 32 teeth divided into two groups of 16 teeth each. In one group teeth underwent pulpotomy, in the other high pulpotomy. Evaluation of root growth was recorded from radiographs (pre-treatment, 3 and 12 months following treatment) and by Demjrian's scale for dental maturity and tooth age determination. On the basis of radiographic analysis, immature teeth with affected pulp treated with HAP, both with pulpotomy and high pulpotomy, reached the same stage of root development as control teeth in 50% of cases at 3-months radiographic assessment. After 12 months all tested teeth had the same rate of root development as control teeth, except for 1 of 8 with high pulpotomy. Dentinal bridge was radiographically visible in 50% and 87.5% of pulpotomized teeth after 3 and 12 months, respectively. Neither obliteration of the root canal, presence of denticles nor the presence of deformities in the periapical region were found in any of the observed teeth., Lečenja aficirane pulpe zuba sa nezavršenim rastom korena je još uvek predmet stručnih i naučnih rasprava, između ostalog i zbog neželjenih efekata tradicionalnih preparata na bazi kalcijum hidroksida. Biokeramički materijali se već nekoliko decenija primenjuju u različitim granama medicine, a hidroksiapatit, kao jedna od dve forme kalcijum-fosfatne keramike, ima gotovo istovetan sastav kao neorganski deo kosti, pa je već prihvaćen u endodontskom lečenju zuba sa završ enim rastom korena. Cilj ovog rada je bio da se ispita uticaj hidroksiapatita na apeksogenezu u zuba sa nezavršenim rastom korena i aficiranom pulpom. Ispitivanjem je bilo obuhvaćeno na osam mladih majmuna Cercopithecus Aethiops sa nezavršenim rastom korena zuba. Sintetički hidroksiapatit, veličine čestica od 100 μm je primenjen na trideset dva zuba, podeljenih u dve jednake grupe kod kojih je všena apulpotomija, odnosno visoka pulpotomija. Rendgenološ ka evaluacija rasta korena zuba je vršena pre terapije, kao i tri i dvanaest mesici posle primene HAP, a na osnovu Demjrianove skale za određivanje zrelosti zuba. Na osnovu rendgenološke analize posle 3 meseca je nađeno da je brzina razvoja korena kako pulpotomisanih, tako i visoko pulpotomisanih zuba kod kojih je primenjen HAP bila u 50% slučajeva ista kao kod kontrolnih zuba. Posle 12 meseci stepen razvoja korena zuba je u svih ispitivanih zuba (osim kod jednog od osam zuba sa izvršenom visokom pulpotomijom) bio isti kao u kontrolnih zuba. Dentinski most je bio vidljiv radiološkom analizom u 50% odnosno 87,5% eksperimentalnih zuba posle 3, odnosno posle 12 meseci. Ni u jednom pregledanom zubu rendgenološki nije uočena obliteracija kanala korena, kao ni dentikli ni deformiteti u periapeksnom predelu.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys, Uticaj hidroksiapatita na apeksogenezu u majmuna - klinička studija",
volume = "58",
number = "4",
pages = "395-409",
doi = "10.2298/AVB0804395P"
}

Petrović, V., Marković, D., Čakić, S.,& Krstić, N.. (2008). Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 58(4), 395-409.
https://doi.org/10.2298/AVB0804395P

Petrović V, Marković D, Čakić S, Krstić N. Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys. in Acta veterinaria. 2008;58(4):395-409.
doi:10.2298/AVB0804395P .

Petrović, Vanja, Marković, Dejan, Čakić, Saša, Krstić, N., "Clinical study on the influence of hydroxyapatite on apexogenesis in monkeys" in Acta veterinaria, 58, no. 4 (2008):395-409,
https://doi.org/10.2298/AVB0804395P . .

TY  - THES
AU  - Petrović, Vanja
PY  - 2007
UR  - https://plus.sr.cobiss.net/opac7/bib/33524751
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/448
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Mogućnosti primene hidroksiapatita u apeksogenezi
UR  - https://hdl.handle.net/21.15107/rcub_smile_448
ER  - 

@phdthesis{
author = "Petrović, Vanja",
year = "2007",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Mogućnosti primene hidroksiapatita u apeksogenezi",
url = "https://hdl.handle.net/21.15107/rcub_smile_448"
}

Petrović, V.. (2007). Mogućnosti primene hidroksiapatita u apeksogenezi. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_448

Petrović V. Mogućnosti primene hidroksiapatita u apeksogenezi. 2007;.
https://hdl.handle.net/21.15107/rcub_smile_448 .

Petrović, Vanja, "Mogućnosti primene hidroksiapatita u apeksogenezi" (2007),
https://hdl.handle.net/21.15107/rcub_smile_448 .

TY  - JOUR
AU  - Marković, Dejan
AU  - Petrović, Vanja
AU  - Krstić, N.
AU  - Lazarević-Macanović, Mirjana
AU  - Nikolić, Zorana
PY  - 2007
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1321
AB  - The treatment of pulp in teeth with incomplete apex formation is still a clinical challenge. In addition to the most widely used medication for this purpose, calcium hydroxide, other materials have also been tested. Following the use of synthetic biomaterials for restoring bone tissue, and considering their recognized biocompatibility and bioconductivity, our intention was to explore the possibility of using synthetic biomaterials in the endodontic treatment of permanent teeth with incomplete apex formation. The aim of this study was to observe the effectiveness of hydroxyapatite in apexogenesis of young permanent teeth. In this study a 100 µm synthetic hydroxyapatite material, Beohap (HAP) powder, was applied to 24 teeth in 3 dogs of 5.5 months of age, after incomplete root development was established on radiographs. The treated teeth were radiographed monthly and the radiographs compared with those of the corresponding teeth on the other side of the jaw until completion of apex growth. The tested teeth were divided into three groups according to the method of treatment: the first was direct pulp capping, the second was amputation of the pulp at the enamelcement junction and the third was high amputation at the radiographically identified point of root growth. On the basis of radiographic analysis, apex formation was successful in all test groups, with no significant differences between the three groups and the controls (Fisher's and χ 2 test). Deformities of the root apex were observed in two teeth (25%) in the third group.
AB  - Tretman pulpe u vreme kada još uvek traje rast i razvoj korena predstavlja i dalje klinički izazov. Pored kalcijum hidroksida, najčešće i najduže upotrebljavanog medikamenta u ovakvim slučajevima, svakodnevno se testiraju i mnogi drugi materijali. Nakon što su se sintetski biomaterijali pokazali uspešnim u restauraciji koštnog tkiva uz njihovu priznatu biokompatibilnost i biokonduktivnost, naša namera je bila da istražimo mogućnost primene hidroksiapatita kao sintetskog biomaterijala u endodontskom tretmanu zuba sa nezavršenim rastom korena. U ovom istraživanju primenjen je Beohap, sintetski hidroksiapatit, prosečne veličine čestica =100 µm, aplikovan na 24 zuba sa nezavršenim rastom korena kod tri psa uzrasta 5,5 meseci. Uzrorci su kontrolisani radiografski i poređeni sa kontralateralnim netretiranim zubima do završetka rasta korena. Tretirani zubi su podeljeni u tri grupe: u prvoj je urađeno direktno prekrivanje pulpe, u drugoj je pulpa uklonjena do cementno-gleđne granice, a u trećoj je pulpa uklonjena do radiografski vidljivog vrha korena. Na osnovu analize rendgen filmova utvrđeno je da je formiranje vrha korena bilo završeno u sve tri grupe bez statističkih značajnosti razlika (Fisher's i χ 2 testovi) Deformiteti vrha korena uočeni su u 2 uzorka u trećoj grupi (25%).
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta veterinaria
T1  - Radiological assessment of apex formation following use of hydroxyapatite
T1  - Rendgenološka procena apeksogeneze nakon primene hidroksiapatita
VL  - 57
IS  - 2-3
SP  - 275
EP  - 287
DO  - 10.2298/AVB0703275M
ER  - 

@article{
author = "Marković, Dejan and Petrović, Vanja and Krstić, N. and Lazarević-Macanović, Mirjana and Nikolić, Zorana",
year = "2007",
abstract = "The treatment of pulp in teeth with incomplete apex formation is still a clinical challenge. In addition to the most widely used medication for this purpose, calcium hydroxide, other materials have also been tested. Following the use of synthetic biomaterials for restoring bone tissue, and considering their recognized biocompatibility and bioconductivity, our intention was to explore the possibility of using synthetic biomaterials in the endodontic treatment of permanent teeth with incomplete apex formation. The aim of this study was to observe the effectiveness of hydroxyapatite in apexogenesis of young permanent teeth. In this study a 100 µm synthetic hydroxyapatite material, Beohap (HAP) powder, was applied to 24 teeth in 3 dogs of 5.5 months of age, after incomplete root development was established on radiographs. The treated teeth were radiographed monthly and the radiographs compared with those of the corresponding teeth on the other side of the jaw until completion of apex growth. The tested teeth were divided into three groups according to the method of treatment: the first was direct pulp capping, the second was amputation of the pulp at the enamelcement junction and the third was high amputation at the radiographically identified point of root growth. On the basis of radiographic analysis, apex formation was successful in all test groups, with no significant differences between the three groups and the controls (Fisher's and χ 2 test). Deformities of the root apex were observed in two teeth (25%) in the third group., Tretman pulpe u vreme kada još uvek traje rast i razvoj korena predstavlja i dalje klinički izazov. Pored kalcijum hidroksida, najčešće i najduže upotrebljavanog medikamenta u ovakvim slučajevima, svakodnevno se testiraju i mnogi drugi materijali. Nakon što su se sintetski biomaterijali pokazali uspešnim u restauraciji koštnog tkiva uz njihovu priznatu biokompatibilnost i biokonduktivnost, naša namera je bila da istražimo mogućnost primene hidroksiapatita kao sintetskog biomaterijala u endodontskom tretmanu zuba sa nezavršenim rastom korena. U ovom istraživanju primenjen je Beohap, sintetski hidroksiapatit, prosečne veličine čestica =100 µm, aplikovan na 24 zuba sa nezavršenim rastom korena kod tri psa uzrasta 5,5 meseci. Uzrorci su kontrolisani radiografski i poređeni sa kontralateralnim netretiranim zubima do završetka rasta korena. Tretirani zubi su podeljeni u tri grupe: u prvoj je urađeno direktno prekrivanje pulpe, u drugoj je pulpa uklonjena do cementno-gleđne granice, a u trećoj je pulpa uklonjena do radiografski vidljivog vrha korena. Na osnovu analize rendgen filmova utvrđeno je da je formiranje vrha korena bilo završeno u sve tri grupe bez statističkih značajnosti razlika (Fisher's i χ 2 testovi) Deformiteti vrha korena uočeni su u 2 uzorka u trećoj grupi (25%).",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta veterinaria",
title = "Radiological assessment of apex formation following use of hydroxyapatite, Rendgenološka procena apeksogeneze nakon primene hidroksiapatita",
volume = "57",
number = "2-3",
pages = "275-287",
doi = "10.2298/AVB0703275M"
}

Marković, D., Petrović, V., Krstić, N., Lazarević-Macanović, M.,& Nikolić, Z.. (2007). Radiological assessment of apex formation following use of hydroxyapatite. in Acta veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 57(2-3), 275-287.
https://doi.org/10.2298/AVB0703275M

Marković D, Petrović V, Krstić N, Lazarević-Macanović M, Nikolić Z. Radiological assessment of apex formation following use of hydroxyapatite. in Acta veterinaria. 2007;57(2-3):275-287.
doi:10.2298/AVB0703275M .

Marković, Dejan, Petrović, Vanja, Krstić, N., Lazarević-Macanović, Mirjana, Nikolić, Zorana, "Radiological assessment of apex formation following use of hydroxyapatite" in Acta veterinaria, 57, no. 2-3 (2007):275-287,
https://doi.org/10.2298/AVB0703275M . .

TY  - JOUR
AU  - Petrović, Vanja
AU  - Vulićević, Zoran
AU  - Marković, Dejan
PY  - 2003
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/1162
AB  - Sistemic fluoride ingestion has been found to be more effective in its caries- reducing benefits on the smooth surfaces than on the pit and fissures. A greater vulnerability to pit and fissure caries determines the need for occlusal surface specific protection. The objective of this study was to investigate clinical effectiveness of 5 different composite sealants during an 18- month observation period. Tested materials were: Superlux Seal-opak (composite with filler particles), Superlux Seal-transparent Estiseal and Fissurit (clear), and Fissurit F (composite with fluoride). They were evaluated according to modified Cvar&Ryge criteria for: retention (R), marginal adaptation (MA), marginal discoloration (MD), surface texture (ST), and secondary caries (SC). The materials were applied in 87 children 6-7 years of age, on 215 first permanent molars, two different materials for each patient. The results were tested for statistical significance by .2 and Fisher's T-test. The results showed good clinical performance of all tested materials with no statistically significant differences. High effectiveness in occlusal caries prevention rated from 97,30% for Fissurit F, and 98% for Superlux Sealopak, to 100% for all other tested sealants. Pit and fissure sealing is an effective prophylactic measure which should be part of the preventive program.
AB  - Sistemska primena fluorida značajno je doprinela smanjenju incidence karijesa glatkih površina zuba, ali ne i fisura i jamica. Specifičnost okluzalne morfologije zahteva dodatnu profilaktičku meru u vidu zalivanja fisura i jamica specijalno formulisanim materijalima. Cilj ovoga rada bio je ispitivanje kliničke efikasnosti 5 različitih kompozitnih materijala za zalivanje fisura u opservacionom periodu od 18 meseci. Testirani su sledeći materijali, predstavnici tri podvrste kompozitnih zalivača: Superlux Sealopak, (opakni, sa puniocem); Superlux Seal-transparent, Estiseal, i Fissurit (transparentni) i Fissurit F (sa fluorom). Modifikovanim Cvar&Ryge kriterijumima praćeni su retencija (R), marginalna adaptacija (MA), ivična prebojenost (IP,)površinska hrapavost (PH), i pojava sekundarnog karijesa (SK). U ispitivanje je uključeno 87 dece uzrasta 6-7 godina. Svakom pacijentu su na prve stalne molare aplikovana po dva različita materijala na ukupno 215 zuba. Na kraju opservacionog perioda svi testirani materijali pokazali su dobre kliničke osobine bez značajnosti statističkih razlika testiranih.2 i Fisherovim T-testom i visok stepen zaštite od karijesa (od 97,30% za Fissurit F, 98% za Superlux Seal-opak,do 100% za ostale ispitivane materijale). Zalivanje fisura je efikasna profilaktička mera i treba da bude sastavni deo preventivnog programa.
PB  - Srpsko lekarsko društvo - Stomatološka sekcija, Beograd
T2  - Stomatološki glasnik Srbije
T1  - Clinical evaluation of composite materials for pit and fissure sealing
T1  - Kliničko ispitivanje kompozitnih zalivača fisura
VL  - 50
IS  - 2
SP  - 70
EP  - 75
DO  - 10.2298/SGS0302070P
ER  - 

@article{
author = "Petrović, Vanja and Vulićević, Zoran and Marković, Dejan",
year = "2003",
abstract = "Sistemic fluoride ingestion has been found to be more effective in its caries- reducing benefits on the smooth surfaces than on the pit and fissures. A greater vulnerability to pit and fissure caries determines the need for occlusal surface specific protection. The objective of this study was to investigate clinical effectiveness of 5 different composite sealants during an 18- month observation period. Tested materials were: Superlux Seal-opak (composite with filler particles), Superlux Seal-transparent Estiseal and Fissurit (clear), and Fissurit F (composite with fluoride). They were evaluated according to modified Cvar&Ryge criteria for: retention (R), marginal adaptation (MA), marginal discoloration (MD), surface texture (ST), and secondary caries (SC). The materials were applied in 87 children 6-7 years of age, on 215 first permanent molars, two different materials for each patient. The results were tested for statistical significance by .2 and Fisher's T-test. The results showed good clinical performance of all tested materials with no statistically significant differences. High effectiveness in occlusal caries prevention rated from 97,30% for Fissurit F, and 98% for Superlux Sealopak, to 100% for all other tested sealants. Pit and fissure sealing is an effective prophylactic measure which should be part of the preventive program., Sistemska primena fluorida značajno je doprinela smanjenju incidence karijesa glatkih površina zuba, ali ne i fisura i jamica. Specifičnost okluzalne morfologije zahteva dodatnu profilaktičku meru u vidu zalivanja fisura i jamica specijalno formulisanim materijalima. Cilj ovoga rada bio je ispitivanje kliničke efikasnosti 5 različitih kompozitnih materijala za zalivanje fisura u opservacionom periodu od 18 meseci. Testirani su sledeći materijali, predstavnici tri podvrste kompozitnih zalivača: Superlux Sealopak, (opakni, sa puniocem); Superlux Seal-transparent, Estiseal, i Fissurit (transparentni) i Fissurit F (sa fluorom). Modifikovanim Cvar&Ryge kriterijumima praćeni su retencija (R), marginalna adaptacija (MA), ivična prebojenost (IP,)površinska hrapavost (PH), i pojava sekundarnog karijesa (SK). U ispitivanje je uključeno 87 dece uzrasta 6-7 godina. Svakom pacijentu su na prve stalne molare aplikovana po dva različita materijala na ukupno 215 zuba. Na kraju opservacionog perioda svi testirani materijali pokazali su dobre kliničke osobine bez značajnosti statističkih razlika testiranih.2 i Fisherovim T-testom i visok stepen zaštite od karijesa (od 97,30% za Fissurit F, 98% za Superlux Seal-opak,do 100% za ostale ispitivane materijale). Zalivanje fisura je efikasna profilaktička mera i treba da bude sastavni deo preventivnog programa.",
publisher = "Srpsko lekarsko društvo - Stomatološka sekcija, Beograd",
journal = "Stomatološki glasnik Srbije",
title = "Clinical evaluation of composite materials for pit and fissure sealing, Kliničko ispitivanje kompozitnih zalivača fisura",
volume = "50",
number = "2",
pages = "70-75",
doi = "10.2298/SGS0302070P"
}

Petrović, V., Vulićević, Z.,& Marković, D.. (2003). Clinical evaluation of composite materials for pit and fissure sealing. in Stomatološki glasnik Srbije
Srpsko lekarsko društvo - Stomatološka sekcija, Beograd., 50(2), 70-75.
https://doi.org/10.2298/SGS0302070P

Petrović V, Vulićević Z, Marković D. Clinical evaluation of composite materials for pit and fissure sealing. in Stomatološki glasnik Srbije. 2003;50(2):70-75.
doi:10.2298/SGS0302070P .

Petrović, Vanja, Vulićević, Zoran, Marković, Dejan, "Clinical evaluation of composite materials for pit and fissure sealing" in Stomatološki glasnik Srbije, 50, no. 2 (2003):70-75,
https://doi.org/10.2298/SGS0302070P . .

TY  - THES
AU  - Petrović, Vanja
PY  - 1998
UR  - https://plus.sr.cobiss.net/opac7/bib/1024061326
UR  - https://smile.stomf.bg.ac.rs/handle/123456789/332
PB  - Univerzitet u Beogradu, Stomatološki fakultet
T1  - Kliničko i SEM ispitivanje zalivača fisura
UR  - https://hdl.handle.net/21.15107/rcub_smile_332
ER  - 

@mastersthesis{
author = "Petrović, Vanja",
year = "1998",
publisher = "Univerzitet u Beogradu, Stomatološki fakultet",
title = "Kliničko i SEM ispitivanje zalivača fisura",
url = "https://hdl.handle.net/21.15107/rcub_smile_332"
}

Petrović, V.. (1998). Kliničko i SEM ispitivanje zalivača fisura. 
Univerzitet u Beogradu, Stomatološki fakultet..
https://hdl.handle.net/21.15107/rcub_smile_332

Petrović V. Kliničko i SEM ispitivanje zalivača fisura. 1998;.
https://hdl.handle.net/21.15107/rcub_smile_332 .

Petrović, Vanja, "Kliničko i SEM ispitivanje zalivača fisura" (1998),
https://hdl.handle.net/21.15107/rcub_smile_332 .