@article{
author = "Marković-Vasiljković, Biljana and Antić, Svetlana and Jelovac, Drago",
year = "2023",
abstract = "Background/Aim. The depth of invasion of oral cavity car cinoma (OCC) and the nodal involvement define the treat ment selection, outcome, and prognosis of the disease. In de termining the stage of OCC, the most widely applied methods
are computerized tomography (CT) and magnetic resonance
imaging (MRI), whose limitations can be overcome to some
extent by using intraoral ultrasound (IOUS). The aim of the
study was to evaluate the imaging presentation of early-stage
OCC, determine the depth of invasion (DOI) and the greatest
diameter (GD) of the tumor using the IOUS and CT meth ods, and compare them with histopathological (HP) findings.
Methods. The study was designed as a prospective one, with
a time limitation of three months. Eleven patients with clinical
early-stage OCC underwent a native CT examination of the
head and neck as well as a contrast-enhanced phase, and then
IOUS of the lesion was performed. Using both methods, DOI
and GD values were measured, and the values were correlated
with HP findings. The analysis of the obtained data was per formed using the statistical package SPSS 22 and Pearson cor relation coefficient. Results. A significant correlation (p =
0.001) was established between the DOI values measured by
IOUS and CT examination with the measurements obtained
by HP processing. On the other hand, by comparing the GD
measured on IOUS and CT examination, no correlation was
established with the HP report. Conclusion. Measurements
of DOI obtained by IOUS significantly correlated with those
in the HP report, while overcoming the limitations of the CT
method in the evaluation of small-sized tumors and tumors
that cannot be shown due to artifacts., Uvod/Cilj. Dubina invazije karcinoma usne duplje i zah-vaćenost regionalnih limfnih čvorova definišu terapijski modalitet, ishod lečenja i prognozu bolesti. U određivanju stadijuma karcinoma usne duplje, najšire primenjivane metode su kompjuterizovana tomografija (KT) i magnetna rezonanca (MR), čija ograničenja se donekle mogu prevazići upotrebom intraoralnog ultrazvuka (IOUZ). Cilj rada bio je da se proceni vizuelni prikaz karcinoma usne duplje ranog stadijuma, odredi dubina invazije (DI) i najveći dijametar tumora (NDT) metodama IOUZ i KT, a zatim da se uporede sa histopatološkim (HP) nalazom. Metode. Studija je dizajnirana kao prospektivna sa vremenskim ograničen-jem od tri meseca. Kod 11 bolesnika sa ranim kliničkim sta-dijumom karcinoma usne duplje, urađen je nativni i postkontrastni pregled glave i vrata pomoću KT, a potom pregled lezije metodom IOUZ. Koristeći obe metode me-rene su vrednosti DI i NDT, koje su potom korelisane sa HP nalazom. Analiza dobijenih podataka izvršena je upo-trebom statističkog paketa SPSS 22 i Pearson-ovog koeficijenta korelacije. Rezultati. Ustanovljena je značajna korelacija (p = 0,001) između vrednosti DI izmerenih pomoću metoda IOUZ i KT, sa merama dobijenim HP ob-radom. Sa druge strane, upoređivanjem vrednosti za NDT izmerenih na IOUZ i KT pregledu, nije ustanovljena korel-acija sa HP izveštajem. Zaključak. Mere DI dobijene metodom IOUZ značajno su korelisale sa onim u HP izveštaju, uz prevazilaženje ograničenja KT metode u evaluaciji tumora malih dimenzija i tumora koji se zbog artefakata ne mogu prikazati.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Comparative assessment of the depth of invasion of early-stage oral cavity carcinomas based on intraoral ultrasound and computerized tomography findings, Komparativna procena dubine invazije tumora usne duplje u ranom stadijumu na osnovu nalaza intraoralnog ultrazvuka i kompjuterizovane tomografije",
volume = "80",
number = "11",
pages = "921-926",
doi = "10.2298/VSP221202048M"
}